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[PMID]:29364944
[Au] Autor:Noyes N; Cho KC; Ravel J; Forney LJ; Abdo Z
[Ad] Endereço:Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, United States of America.
[Ti] Título:Associations between sexual habits, menstrual hygiene practices, demographics and the vaginal microbiome as revealed by Bayesian network analysis.
[So] Source:PLoS One;13(1):e0191625, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The vaginal microbiome plays an influential role in several disease states in reproductive age women, including bacterial vaginosis (BV). While demographic characteristics are associated with differences in vaginal microbiome community structure, little is known about the influence of sexual and hygiene habits. Furthermore, associations between the vaginal microbiome and risk symptoms of bacterial vaginosis have not been fully elucidated. Using Bayesian network (BN) analysis of 16S rRNA gene sequence results, demographic and extensive questionnaire data, we describe both novel and previously documented associations between habits of women and their vaginal microbiome. The BN analysis approach shows promise in uncovering complex associations between disparate data types. Our findings based on this approach support published associations between specific microbiome members (e.g., Eggerthella, Gardnerella, Dialister, Sneathia and Ruminococcaceae), the Nugent score (a BV diagnostic) and vaginal pH (a risk symptom of BV). Additionally, we found that several microbiome members were directly connected to other risk symptoms of BV (such as vaginal discharge, odor, itch, irritation, and yeast infection) including L. jensenii, Corynebacteria, and Proteobacteria. No direct connections were found between the Nugent Score and risk symptoms of BV other than pH, indicating that the Nugent Score may not be the most useful criteria for assessment of clinical BV. We also found that demographics (i.e., age, ethnicity, previous pregnancy) were associated with the presence/absence of specific vaginal microbes. The resulting BN revealed several as-yet undocumented associations between birth control usage, menstrual hygiene practices and specific microbiome members. Many of these complex relationships were not identified using common analytical methods, i.e., ordination and PERMANOVA. While these associations require confirmatory follow-up study, our findings strongly suggest that future studies of the vaginal microbiome and vaginal pathologies should include detailed surveys of participants' sanitary, sexual and birth control habits, as these can act as confounders in the relationship between the microbiome and disease. Although the BN approach is powerful in revealing complex associations within multidimensional datasets, the need in some cases to discretize the data for use in BN analysis can result in loss of information. Future research is required to alleviate such limitations in constructing BN networks. Large sample sizes are also required in order to allow for the incorporation of a large number of variables (nodes) into the BN, particularly when studying associations between metadata and the microbiome. We believe that this approach is of great value, complementing other methods, to further our understanding of complex associations characteristic of microbiome research.
[Mh] Termos MeSH primário: Higiene
Menstruação
Microbiota
Comportamento Sexual
Vagina/microbiologia
[Mh] Termos MeSH secundário: Teorema de Bayes
Feminino
Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180125
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0191625


  2 / 11966 MEDLINE  
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[PMID]:29430892
[Au] Autor:Novikov SM; Fokin MV; Unguryanu TN
[Ti] Título:[Actual problem of methodology and development of evidence-based health risk assessment associated with chemical exposure].
[So] Source:Gig Sanit;95(8):711-6, 2016.
[Is] ISSN:0016-9900
[Cp] País de publicação:Russia (Federation)
[La] Idioma:rus
[Ab] Resumo:Paramount problems of the development of the assessment of population health risks associated with the chemical exposure in Russia are considered on the ground of critical analysis of reports devoted to methodological issues of the risk assessment and guidelines published since 2010. Causes of the lack in progress of risk assessment are discussed. The information of executed research revealed the significant retardation number of Russian publications devoted to the evidence-based health risk assessment compare to worldwide trend. The analysis of publications according to evidence-based health risk assessment in Russia in 1998 - 2012 demonstrated methodical problems to be leading to the underestimation of the real risk to population's health. There are demonstrated directions in the renewal of methodology and practice of hygienic standardization on the basis of the risk assessment. The comparative analysis of values of uncertainty factors (modifying factors, conversion factors) used for extrapolation and accepted in different countries and organizations was made. The system of extrapolation coefficients of DNEL (Derive No-Effect Level) is presented. The leading principles of modern toxicology and risk assessment based on strict scientific proofs are showed. Criteria of evidence-based toxicology and risk assessment are presented.Among actual problems which demand their decision there are considered: the assessment of combined action in regulatory toxicology; expansion of spheres of the application of health risk assessment methodology; the improvement ofpreparation and certification of experts in the field of health risk assessment; need of check of dispersion models and their replacement by more modern models; the improvement of exposure assessment with taking into account the international requirements; the assessment of regional exposure factors; expansion of atmospheric air monitoring in all the large cities of Russia.
[Mh] Termos MeSH primário: Exposição Ambiental
Substâncias Perigosas
Medição de Risco
[Mh] Termos MeSH secundário: Exposição Ambiental/prevenção & controle
Exposição Ambiental/normas
Poluentes Ambientais/análise
Poluentes Ambientais/normas
Prática Clínica Baseada em Evidências
Substâncias Perigosas/análise
Substâncias Perigosas/normas
Seres Humanos
Higiene/normas
Saúde Pública/métodos
Medição de Risco/métodos
Medição de Risco/normas
Federação Russa
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Environmental Pollutants); 0 (Hazardous Substances)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180301
[Lr] Data última revisão:
180301
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180213
[St] Status:MEDLINE


  3 / 11966 MEDLINE  
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[PMID]:29425007
[Au] Autor:Rakitsky VN; Tulakin AV; Sinitskaya TA; Tsyplakova GV; Gorshkova EF; mpleeva GP; Morozova LF; Kozyreva ON; Pivneva OS
[Ti] Título:[The improvement of methodical approaches of hygienic regulation of pesticides in water bodies].
[So] Source:Gig Sanit;95(7):675-8, 2016.
[Is] ISSN:0016-9900
[Cp] País de publicação:Russia (Federation)
[La] Idioma:rus
[Ab] Resumo:The article highlights the methodical features of hygienic regulation of pesticide preparation in water bodies, concretizes and supplements (specified) number of positions of the acting current methodical document on hygienic evaluation of new pesticides. From the position of the comprehensive hygienic standardization there are marked principles of the study of MPC for pesticides in water bodies, there is substantiated the expediency of expanding the arsenal of methods for determination of threshold concentrations of pesticides on the impact on organoleptic properties of water and sanitary regime of reservoirs, shows the role and importance of hydrolysis processes of active ingredients ofpesticides in water, which should be considered in the assessment of the impact of drugs on the processes of self-purification of water bodies.
[Mh] Termos MeSH primário: Higiene/normas
Praguicidas
Poluentes Químicos da Água
[Mh] Termos MeSH secundário: Monitoramento Ambiental/métodos
Monitoramento Ambiental/normas
Seres Humanos
Concentração Máxima Permitida
Praguicidas/análise
Praguicidas/normas
Poluentes Químicos da Água/análise
Poluentes Químicos da Água/normas
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Pesticides); 0 (Water Pollutants, Chemical)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180301
[Lr] Data última revisão:
180301
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180210
[St] Status:MEDLINE


  4 / 11966 MEDLINE  
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[PMID]:29424498
[Au] Autor:Ermakova NA; Melnichenko PI; Prokhorov NI; Timoshenko KT; Matveev AA; Kostina EV; Minnibaev TS
[Ti] Título:[Lifestyle and health of students].
[So] Source:Gig Sanit;95(6):558-63, 2016.
[Is] ISSN:0016-9900
[Cp] País de publicação:Russia (Federation)
[La] Idioma:rus
[Ab] Resumo:The article presents the results of the evaluation of the most significant risk factors related to lifestyle and health of medical students of different courses andfaculties. The obtained data testify that out of the total number of factors that have a significant influence on the formation of bases of student's healthy lifestyle and health, the most typical are the mode of employment, the total workload, material well-being, living conditions of the majority of today's students, as well as the conditions of nutrition, physical activity, the presence or absence of such factors as smoking, frequency of consumption of alcoholic beverages.
[Mh] Termos MeSH primário: Estilo de Vida Saudável
Estudantes/psicologia
Universidades/normas
[Mh] Termos MeSH secundário: Adulto
Feminino
Comportamentos Relacionados com a Saúde
Disparidades nos Níveis de Saúde
Seres Humanos
Higiene/normas
Masculino
Federação Russa/epidemiologia
Fatores Socioeconômicos
Ensino/organização & administração
Ensino/normas
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180301
[Lr] Data última revisão:
180301
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180210
[St] Status:MEDLINE


  5 / 11966 MEDLINE  
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[PMID]:29424212
[Au] Autor:Kuchma VR; Makarova AY
[Ti] Título:[Hygiene of the life activity of children and adolescents is the basis of welfare of young generation of Russians (to the 90th anniversary of the Department of hygiene of education - hygiene of children and adolescents of the Imperial Moscow University - 1st Moscow State University - 1st Moscow State Medical University - Moscow Medical Academy - First Moscow State Medical University named after I.M. Sechenov)].
[So] Source:Gig Sanit;95(5):491-6, 2016.
[Is] ISSN:0016-9900
[Cp] País de publicação:Russia (Federation)
[La] Idioma:rus
[Mh] Termos MeSH primário: Saúde do Adolescente/história
Saúde da Criança/história
Higiene/história
[Mh] Termos MeSH secundário: Adolescente
Aniversários e Eventos Especiais
Criança
Bem-Estar da Criança/história
História do Século XX
História do Século XXI
Seres Humanos
Federação Russa
Universidades/história
[Pt] Tipo de publicação:HISTORICAL ARTICLE; JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180301
[Lr] Data última revisão:
180301
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180210
[St] Status:MEDLINE


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[PMID]:29179846
[Au] Autor:Patry C; Closier S; Lafon É; Carlier-Verhaeghe C; Kerrien A; Bertrand A; Caudron E
[Ad] Endereço:Hôpital Bretonneau, équipe mobile gériatrique externe, 23 rue Joseph de Maistre, 75018, Paris, France.
[Ti] Título:[Supporting people with Diogenes syndrome].
[Ti] Título:Accompagnement des personnes atteintes du syndrome de Diogène..
[So] Source:Rev Infirm;66(236):34-36, 2017 Dec.
[Is] ISSN:1293-8505
[Cp] País de publicação:France
[La] Idioma:fre
[Ab] Resumo:Diogenes syndrome is a chronic condition often affecting elderly people, especially those living in isolation. It is characterised by self-neglect and compulsive hoarding. Medico-social professionals working with people in their home, have reflected on levers to help improve the complex support of these patients.
[Mh] Termos MeSH primário: Colecionismo
Higiene
Isolamento Social
[Mh] Termos MeSH secundário: Idoso
Colecionismo/diagnóstico
Colecionismo/psicologia
Colecionismo/terapia
Seres Humanos
Síndrome
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180301
[Lr] Data última revisão:
180301
[Sb] Subgrupo de revista:N
[Da] Data de entrada para processamento:171129
[St] Status:MEDLINE


  7 / 11966 MEDLINE  
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[PMID]:27774794
[Au] Autor:Seay JS; Mandigo M; Kish J; Menard J; Marsh S; Kobetz E
[Ad] Endereço:a Miller School of Medicine , University of Miami , Miami , FL , USA.
[Ti] Título:Intravaginal practices are associated with greater odds of high-risk HPV infection in Haitian women.
[So] Source:Ethn Health;22(3):257-265, 2017 Jun.
[Is] ISSN:1465-3419
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: Haitian women have the highest incidence of cervical cancer within the Western hemisphere. Intravaginal hygiene practices have been linked with human papilloma virus (HPV) infection and cervical dysplasia. These practices, known as 'twalet deba' in Haitian Creole, are common among Haitian women and are performed with various natural and synthetic agents. As part of a community-based participatory research initiative aimed at reducing cervical cancer disparities in rural Haiti, we explored the use of intravaginal agents and their associations with high-risk HPV infection. DESIGN: Community Health Workers recruited 416 women for cervical self-sampling from two neighborhoods within Thomonde, Haiti. Participants were interviewed regarding intravaginal hygiene practices and completed a cervical self-sampling procedure. Cervical samples were analyzed for the presence of high-risk HPV infection. Associations between each intravaginal agent and high-risk HPV infection were examined via univariate logistic regression analyses, as well as via multivariate analyses controlling for sociodemographic factors and concurrent agent use. RESULTS: Nearly all women (97.1%) performed twalet deba, using a variety of herbal and commercially produced intravaginal agents. Approximately 11% of the participants tested positive for high-risk HPV. Pigeon pea and lime juice were the only agents found to be associated with high-risk HPV in the univariate analyses, with women who used these agents being approximately twice as likely to have high-risk HPV as those who did not. Only pigeon pea remained significantly associated with high-risk HPV after controlling for sociodemographic factors and concurrent agent use. CONCLUSION: Two agents, pigeon pea and lime juice, may contribute to risk for HPV infection in this population. Results suggest that in addition to cervical cancer screening interventions, future preventive initiatives should focus on minimizing risk by advocating for the use of less-toxic twalet deba alternatives.
[Mh] Termos MeSH primário: Conhecimentos, Atitudes e Prática em Saúde/etnologia
Higiene
Infecções por Papillomavirus/etnologia
Ducha Vaginal/efeitos adversos
[Mh] Termos MeSH secundário: Administração Intravaginal
Adulto
Compostos de Alúmen/administração & dosagem
Cajanus
Citrus aurantiifolia
Pesquisa Participativa Baseada na Comunidade
Feminino
Sucos de Frutas e Vegetais
Haiti/epidemiologia
Seres Humanos
Infecções por Papillomavirus/epidemiologia
Infecções por Papillomavirus/virologia
Preparações de Plantas/administração & dosagem
Permanganato de Potássio/administração & dosagem
Fatores de Risco
Sabões/administração & dosagem
Ducha Vaginal/métodos
Saúde da Mulher/etnologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Alum Compounds); 0 (Plant Preparations); 0 (Soaps); 00OT1QX5U4 (Potassium Permanganate); 34S289N54E (aluminum sulfate)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180301
[Lr] Data última revisão:
180301
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161025
[St] Status:MEDLINE
[do] DOI:10.1080/13557858.2016.1246423


  8 / 11966 MEDLINE  
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[PMID]:29393302
[Au] Autor:Rakatansky H
[Ad] Endereço:Clinical Professor of Medicine Emeritus,The Warren Alpert Medical School of Brown University.
[Ti] Título:When the competent patient refuses personal care.
[So] Source:R I Med J (2013);101(1):10-11, 2018 Feb 02.
[Is] ISSN:2327-2228
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:[Full article available at http://rimed.org/rimedicaljournal-2018-02.asp].
[Mh] Termos MeSH primário: Hospitalização
Higiene
Competência Mental
Paraplegia/terapia
Recusa do Paciente ao Tratamento/ética
[Mh] Termos MeSH secundário: Seres Humanos
Masculino
Meia-Idade
Paraplegia/psicologia
Recusa do Paciente ao Tratamento/psicologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180214
[Lr] Data última revisão:
180214
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180203
[St] Status:MEDLINE


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[PMID]:29190837
[Au] Autor:Parrillo A; Feller E
[Ad] Endereço:medical student at The Warren Alpert Medical School of Brown University.
[Ti] Título:Menstrual hygiene plight of homeless women, a public health disgrace.
[So] Source:R I Med J (2013);100(12):14-15, 2017 Dec 01.
[Is] ISSN:2327-2228
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:[Full article available at http://rimed.org/rimedicaljournal-2017-12.asp].
[Mh] Termos MeSH primário: Política de Saúde
Acesso aos Serviços de Saúde
Pessoas em Situação de Rua
Higiene
Produtos de Higiene Menstrual
Saúde Pública
[Mh] Termos MeSH secundário: Feminino
Política de Saúde/economia
Política de Saúde/legislação & jurisprudência
Acesso aos Serviços de Saúde/economia
Acesso aos Serviços de Saúde/legislação & jurisprudência
Seres Humanos
Higiene/economia
Produtos de Higiene Menstrual/economia
Saúde Pública/economia
Saúde Pública/legislação & jurisprudência
Impostos
Estados Unidos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180214
[Lr] Data última revisão:
180214
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171201
[St] Status:MEDLINE


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[PMID]:27775463
[Au] Autor:Mpyet C; Muhammad N; Adamu MD; Muazu H; Umar MM; Goyol M; Onyebuchi U; Chima I; Idris H; William A; Isiyaku S; Nwobi B; Flueckiger RM; Willis R; Pavluck A; Chu BK; Olobio N; Solomon AW
[Ad] Endereço:a Department of Ophthalmology , University of Jos , Jos , Nigeria.
[Ti] Título:Prevalence of Trachoma in Katsina State, Nigeria: Results of 34 District-Level Surveys.
[So] Source:Ophthalmic Epidemiol;23(sup1):55-62, 2016.
[Is] ISSN:1744-5086
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:PURPOSE: To determine the local government area (LGA)-level prevalence of trachoma in all 34 LGAs of Katsina State. METHODS: A population-based prevalence survey was conducted in each LGA of Katsina State, using the Global Trachoma Mapping Project methodology. We used a 3-stage cluster random sampling strategy to select 25 households from each of 25 clusters. We examined all residents of selected households aged 1 year and older for the clinical signs of trachomatous inflammation-follicular (TF), trachomatous inflammation-intense and trichiasis, using the World Health Organization (WHO) simplified grading scheme. RESULTS: We examined 129,281 persons. Six LGAs had a TF prevalence ≥10%, and another six LGAs had a TF prevalence between 5% and 9.9%; all 12 require mass drug administration with azithromycin plus other interventions. The prevalence of trichiasis was ≥1.0% in 13 LGAs, and there is a need to perform trichiasis surgery in over 26,000 persons to reach targets set by the WHO for elimination of trichiasis. CONCLUSION: The prevalence of TF is generally low in Katsina state, but urgent steps must be taken to implement the full SAFE strategy (surgery, antibiotics, facial cleanliness, environmental improvement) in at least 12 LGAs while also stepping up efforts to provide community-based trichiasis surgery throughout the whole state, in order to make trachoma elimination by 2020 a reality.
[Mh] Termos MeSH primário: Tracoma/epidemiologia
Triquíase/epidemiologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Idoso de 80 Anos ou mais
Antibacterianos/uso terapêutico
Criança
Pré-Escolar
Estudos Transversais
Feminino
Inquéritos Epidemiológicos
Seres Humanos
Higiene/normas
Lactente
Recém-Nascido
Masculino
Meia-Idade
Nigéria/epidemiologia
Prevalência
Saneamento/normas
Tracoma/prevenção & controle
Abastecimento de Água/normas
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T; RESEARCH SUPPORT, U.S. GOV'T, NON-P.H.S.
[Nm] Nome de substância:
0 (Anti-Bacterial Agents)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:180123
[Lr] Data última revisão:
180123
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161025
[St] Status:MEDLINE
[do] DOI:10.1080/09286586.2016.1236975



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