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[PMID]:28421456
[Au] Autor:Laing P; Pham T; Taylor LJ; Fang J
[Ad] Endereço:Department of Gastroenterology and Hepatology, University of Utah, Salt Lake City, UT, USA.
[Ti] Título:Filling the Void: A Review of Intragastric Balloons for Obesity.
[So] Source:Dig Dis Sci;62(6):1399-1408, 2017 Jun.
[Is] ISSN:1573-2568
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Endoscopic bariatric therapies are predicted to become much more widely used in North America for obese patients who are not candidates for bariatric surgery. Of all the endoscopic bariatric therapies, intragastric balloons (IGBs) have the greatest amount of clinical experience and published data supporting their use. Three IGBs are FDA approved and are now commercially available in the USA (Orbera, ReShape Duo, and Obalon) with others likely soon to follow. They are generally indicated for patients whose BMI ranges from 30 to 40 mg/kg and who have failed to lose weight with diet and exercise. IGBs have been shown to be safe, effective, and relatively straightforward to place and remove. Accommodative symptoms commonly occur within the initial weeks post-placement; however, major complications are rare. Gastric ulceration can occur in up to 10% of patients, while balloon deflation with migration and bowel obstruction occurs in <1% of patients. The effectiveness of the Orbera and ReShape Duo IGBs ranges from 25 to 50% EWL (excess weight loss) after 6 months of therapy. The use of IGBs is likely to grow dramatically in the USA, and gastroenterologists and endoscopists should be familiar with their indications/contraindications, efficacy, placement/removal, and complications.
[Mh] Termos MeSH primário: Bariatria/instrumentação
Balão Gástrico
Obesidade/terapia
[Mh] Termos MeSH secundário: Bariatria/efeitos adversos
Contraindicações
Balão Gástrico/efeitos adversos
Seres Humanos
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1708
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170420
[St] Status:MEDLINE
[do] DOI:10.1007/s10620-017-4566-2


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[PMID]:28249576
[Au] Autor:Padwal RS; Klarenbach S; Sharma AM; Fradette M; Jelinski SE; Edwards A; Majumdar SR
[Ad] Endereço:Department of Medicine, University of Alberta, Edmonton, Alberta, Canada. rpadwal@ualberta.ca.
[Ti] Título:The evaluating self-management and educational support in severely obese patients awaiting multidisciplinary bariatric care (EVOLUTION) trial: principal results.
[So] Source:BMC Med;15(1):46, 2017 Mar 02.
[Is] ISSN:1741-7015
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: In Canada, demand for multidisciplinary bariatric (obesity) care far outstrips capacity. Consequently, prolonged wait times exist that contribute to substantial health impairments. A supportive, educational, self-management intervention (with in-person and web-based versions) for patients wait-listed for bariatric care has already been implemented in Northern and Central Alberta, Canada, but its effectiveness is unknown. The objective of this trial is to evaluate the clinical and economic outcomes of two self-management programs of varying intensity that are currently in use. METHODS: We conducted a pragmatic, prospective, parallel-arm, randomized controlled trial of 651 wait-listed patients from two regional bariatric programs. Patients were randomized to (1) an in-person, group-based intervention (13 sessions; n = 215) or (2) a web-based intervention (13 modules; n = 225) or (3) control group (printed educational materials; n = 211). After randomization, subjects had 3 months to review the content assigned to them (the intervention period) prior to bariatric clinic entry. The primary outcome was the proportion of patients achieving 5% weight loss at 9 months. Intention-to-treat two-way comparisons were performed and adjusted for baseline age, sex, site and body mass index. RESULTS: At baseline, mean age was 40.4 ± 9.8 years, mean weight was 134.7 ± 25.2 kg, mean body mass index was 47.7 ± 7.0 kg/m and 83% of participants were female. A total of 463 patients (71%) completed 9 months follow-up. At least 5% weight loss was achieved by 24.2% of those in the in-person strategy, 24.9% for the web-based strategy and 21.3% for controls (adjusted p value = 0.26 for in-person vs. controls, 0.28 for web-based vs. controls, 0.96 for in-person vs. web-based). Absolute and relative (% of baseline) mean weight reductions were 3.7 ± 7.1 kg (2.7 ± 5.4%) for in-person strategy, 2.8 ± 6.7 kg (2.0 ± 4.8%) for web-based and 2.9 ± 8.8 kg (1.9 ± 5.9%) for controls (p > 0.05 for all comparisons). No between-group differences were apparent for any clinical or humanistic secondary outcomes. Total annual costs in Canadian dollars were estimated at $477,000.00 for the in-person strategy, $9456.78 for the web-based strategy and $2270.31 for provision of printed materials. DISCUSSION: Two different self-management interventions were no more effective and were more costly than providing printed education materials to severely obese patients. Our findings underscore the need to develop more potent interventions and the importance of comprehensively evaluating self-management strategies before widespread implementation. TRIAL REGISTRATION: ClinicalTrials.gov, NCT01860131 . Registered 17 May 2013.
[Mh] Termos MeSH primário: Bariatria/métodos
Obesidade
Educação de Pacientes como Assunto/métodos
Autocuidado/métodos
[Mh] Termos MeSH secundário: Adulto
Bariatria/economia
Canadá
Feminino
Seres Humanos
Masculino
Meia-Idade
Educação de Pacientes como Assunto/economia
Estudos Prospectivos
Autocuidado/economia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170602
[Lr] Data última revisão:
170602
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170303
[St] Status:MEDLINE
[do] DOI:10.1186/s12916-017-0808-6


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[PMID]:28249286
[Au] Autor:Patton A; Khan FH; Kohli R
[Ad] Endereço:Ohio University College of Osteopathic Medicine, Athens, Ohio, USA.
[Ti] Título:Impact of Fibroblast Growth Factors 19 and 21 in Bariatric Metabolism.
[So] Source:Dig Dis;35(3):191-196, 2017.
[Is] ISSN:1421-9875
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Bariatric surgery is a popular and effective therapeutic intervention for obesity, which is an abnormal health condition that is prevalent worldwide. Metabolic improvements that precede weight loss after bariatric surgery may be mediated, in part, through the fibroblast growth factor (FGF) 15/19 and FGF21 signaling pathways. Both FGF15/19 and FGF21 are hormone-like members of the FGF family and exert their metabolic effects in an endocrine manner. Enhanced bile acid recycling after bariatric surgery leads to increased circulating levels of FGF15/19 in the distal small intestine. Synthesis of FGF21 is upregulated predominately in the fasting state through peroxisome proliferator-activated receptor pathways and to a lesser extent by FGF15/19. Key Messages: The biological functions of FGF15/19 and FGF21 are diverse and complicated. The tissue targeted effects of FGF15/19 and FGF21 of importance after bariatric surgery include the regulation of hepatic bile acid biosynthesis and ketogenesis as well as thermogenesis in adipose tissue, respectively. Furthermore, FGF15/19 and FGF21 function to regulate carbohydrate and lipid metabolism. CONCLUSION: The long-term effects of bariatric surgery on weight loss are undisputable. However, the mechanism for improvements in glucose and lipid homeostasis observed shortly after bariatric surgery is less understood. This review article attempts to describe the known metabolic effects of FGF15/19 and FGF21 that may potentiate these improvements after bariatric surgery.
[Mh] Termos MeSH primário: Bariatria
Fatores de Crescimento de Fibroblastos/metabolismo
Obesidade/metabolismo
[Mh] Termos MeSH secundário: Animais
Ácidos e Sais Biliares/metabolismo
Encéfalo/metabolismo
Seres Humanos
Fígado/metabolismo
Transdução de Sinais
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Bile Acids and Salts); 62031-54-3 (Fibroblast Growth Factors)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170501
[Lr] Data última revisão:
170501
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170302
[St] Status:MEDLINE
[do] DOI:10.1159/000450910


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[PMID]:28184958
[Au] Autor:Kim JM; Kim MD; Han K; Muqmiroh L; Kim SU; Kim GM; Kwon J; Park SI; Won JY; Lee DY
[Ad] Endereço:Department of Radiology, Research Institute of Radiological Science, Severance Hospital, Yonsei University College of Medicine, 50 Yonsei-ro, Shinchon-dong, Seodaemun-gu, Seoul, 120-752, Republic of Korea.
[Ti] Título:Bariatric Arterial Embolization with Non-spherical Polyvinyl Alcohol Particles for Ghrelin Suppression in a Swine Model.
[So] Source:Cardiovasc Intervent Radiol;40(5):744-749, 2017 May.
[Is] ISSN:1432-086X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PURPOSE: To evaluate the effect of bariatric arterial embolization (BAE) with non-spherical polyvinyl alcohol (PVA) particles on systemic ghrelin levels, weight change, and gastric ulceration risk in a swine model. MATERIALS AND METHODS: From March 2014 to February 2015, ten healthy swine were used in the study (mean weight 31.5 kg; range 24.0-41.5 kg). The animals were randomly assigned to two groups: the embolized group (n = 5) in which BAE was performed and the control group (n = 5). In the embolized group, BAE was performed by selectively infusing 150-250 or 50-150 µm PVA into the gastric arteries that supplied the fundus of the stomach. In the control group, a sham procedure was performed with saline infusion. Plasma ghrelin levels were prospectively obtained at baseline and every 2 weeks thereafter. Endoscopy was performed 3 weeks after BAE to see whether any gastric ulcer occurred. To determine the durability of the occluded arteries, repeated celiac trunk angiography was performed 8 weeks after BAE. Then, all the swine were killed and necropsies were performed. RESULTS: The mean post-procedure ghrelin value decreased by 370.0 pg/mL in the embolized group at week 3 (mean 536.0 ± 334.3 pg/mL) and week 5 (mean 515.0 ± 150.0 pg/mL, p < 0.05) relative to baseline (880.0 ± 559.5 pg/mL), respectively, but ghrelin levels were not significantly decreased between the embolized and control groups. There was a significant body weight change as follows: 35.1 ± 9.5 to 46.6 ± 15.7 kg and 31.8 ± 5.8 to 41.2 ± 6.6 kg at baseline and endpoint in the control and embolized groups, respectively (p < 0.05). However, the difference between groups was not significant at endpoint. In the embolized group, ulcerations were identified in three animals (60%) and the recanalization of the embolized arteries was noted on follow-up angiography in three animals (60%), respectively. CONCLUSION: BAE with PVA particles can transiently suppress ghrelin levels in embolized animals, but levels are not significantly different compared to controls. Stomach ulcerations were identified in 60% of the embolized animals.
[Mh] Termos MeSH primário: Bariatria
Embolização Terapêutica/métodos
Grelina/sangue
Álcool de Polivinil/administração & dosagem
Estômago/irrigação sanguínea
Estômago/metabolismo
[Mh] Termos MeSH secundário: Angiografia
Animais
Peso Corporal
Embolização Terapêutica/efeitos adversos
Modelos Animais
Estômago/diagnóstico por imagem
Úlcera Gástrica/etiologia
Suínos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Ghrelin); 9002-89-5 (Polyvinyl Alcohol)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170601
[Lr] Data última revisão:
170601
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170211
[St] Status:MEDLINE
[do] DOI:10.1007/s00270-017-1600-x


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[PMID]:27860058
[Au] Autor:Tarrant M; Khan SS; Farrow CV; Shah P; Daly M; Kos K
[Ad] Endereço:University of Exeter Medical School, University of Exeter, UK.
[Ti] Título:Patient experiences of a bariatric group programme for managing obesity: A qualitative interview study.
[So] Source:Br J Health Psychol;22(1):77-93, 2017 Feb.
[Is] ISSN:2044-8287
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: People with obesity experience a range of physical and psychological ill-health outcomes. This study examined patients' experiences of a group-based programme for the management of morbid obesity delivered within the UK National Health Service. The focus of the study was on the emerging dynamic of the group and patients' perceptions of its impact on health outcomes. DESIGN: A qualitative interview study was conducted and involved patients recruited from a Tier 3 bariatric service in South West England. Verbatim transcripts were analysed using thematic analysis. METHODS: Twenty patients (12 females) with a BMI ≥ 35 kg/m participated in a semi-structured one-to-one interview. Participants had been registered with the bariatric service for at least 6 months. None of the participants had had bariatric surgery. RESULTS: Most participants felt that they had benefited from participating in the group programme and talked about the group as a resource for lifestyle change. Participants' narratives centred on the emergence of a sense of self based upon their participation in the group: establishing psychological connections to other patients, or shared social identity, was regarded as a key mechanism through which the programme's educational material was accessed, and underpinned the experience of social support within the group. Through interaction with other patients, involving the sharing of personal experiences and challenges, participants came to experience their weight 'problem' through a collective lens that they felt empowered them to initiate and sustain individual lifestyle change. DISCUSSION: Bariatric care groups have the potential to support lifestyle change and weight loss and may help address the psychological needs of patients. Nurturing a sense of shared social identity amongst patients with morbid obesity should be a core aim of the care pathway and may provide the foundation for successful translation of dietetic content in group programmes. Statement of contribution What is already known on this subject? Services for people with obesity who require specialist care are often supported by group-based bariatric programmes. There are no specific guidelines for the organization of bariatric groups beyond the recommendation for lifestyle interventions delivered by a multidisciplinary care team. Research with other health conditions suggests that the psychological connections formed between participants in bariatric programmes may play an important role in structuring programme effectiveness. What does this study add? Establishing psychological connections with other patients underpins bariatric patients' group experience. Shared social identity structures behaviour change in patients on bariatric programmes. Nurturing shared social identity should be a core aim of the bariatric care pathway.
[Mh] Termos MeSH primário: Obesidade Mórbida/terapia
Apoio Social
Programas de Redução de Peso
[Mh] Termos MeSH secundário: Adulto
Idoso
Atitude Frente à Saúde
Bariatria
Dietoterapia
Inglaterra
Feminino
Seres Humanos
Masculino
Meia-Idade
Entrevista Motivacional
Educação de Pacientes como Assunto
Psicoterapia de Grupo
Pesquisa Qualitativa
Identificação Social
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170306
[Lr] Data última revisão:
170306
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161119
[St] Status:MEDLINE
[do] DOI:10.1111/bjhp.12218


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[PMID]:27633198
[Au] Autor:Wiggermann N
[Ad] Endereço:Hill-Rom, Batesville, IN, USA. Electronic address: neal.wiggermann@hill-rom.com.
[Ti] Título:Effect of a powered drive on pushing and pulling forces when transporting bariatric hospital beds.
[So] Source:Appl Ergon;58:59-65, 2017 Jan.
[Is] ISSN:1872-9126
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Powered drives designed to assist with moving hospital beds are commercially available but no studies have evaluated whether they reduce the push and pull forces likely contributing to injury in caregivers. This study measured hand forces of 10 caregivers maneuvering a manual and powered bariatric bed through simulated hospital environments (hallway, elevator, and ramp). Peak push and pull forces exceeded previously established psychophysical limits for all activities with the manual bed. For the powered bed, peak forces were significantly (p < 0.05) lower for all tasks, and below psychophysical limits. Powered drive reduced peak forces between 38% (maneuvering into elevator) and 94% (descending ramp). Powered drive also reduced stopping distance by 55%. When maneuvering, the integral of hand force was 34% lower with powered drive, but average forces during straight-line pushing did not differ between beds. Powered drive may reduce the risk of injury or the number of caregivers needed for transport.
[Mh] Termos MeSH primário: Bariatria/instrumentação
Leitos
Saúde do Trabalhador
Traumatismos Ocupacionais/prevenção & controle
Esforço Físico
[Mh] Termos MeSH secundário: Aceleração
Desaceleração
Desenho de Equipamento
Feminino
Seres Humanos
Masculino
Movimento
Recursos Humanos em Hospital
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170910
[Lr] Data última revisão:
170910
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160917
[St] Status:MEDLINE


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[PMID]:28030944
[Au] Autor:Szeliga J; Kupczyk W; Kupczyk K; Chojnowski J; Jackowski M; Ponikowska I
[Ad] Endereço:Department of General, Gastroenterological and Oncological Surgery, Collegium Medicum, Nicolaus Copernicus University, Torun, Poland.
[Ti] Título:Withdrawal from bariatric treatment - an analysis under various demographic conditions.
[So] Source:Ann Agric Environ Med;23(4):688-691, 2016 12 23.
[Is] ISSN:1898-2263
[Cp] País de publicação:Poland
[La] Idioma:eng
[Ab] Resumo:Poland is high on a list of countries affected by epidemics of obesity, a problem that has especially suddenly increased in the post-transformation period. MATERIALS AND METHOD: Documentation of 115 subsequent patients diagnosed with grade 3 obesity, considered eligible for surgical treatment, was analysed since 2015. A subgroup of 68 patients was selected from this group and the included patients who decided to cancel their treatment at various stages. Their history since presentation at the obesity treatment centre, BMI with its history, age, education and place of residence were analysed, followed by a telephone survey. 42 patients were finally contacted. Special attention was placed on the analysis of patients taking into account their place of residence. Patients were divided into inhabitants of rural and urban areas. RESULTS: In the study group of 68 patients, 19 (27.9%) were inhabitants of rural areas and 49 (72.1%) of urban areas. Women accounted for 67.6%, and men for 32.4%. The mean age of patients when they presented for treatment was 43 years. On average, men presented 5 years later compared to women. The mean BMI on qualification for treatment of obesity was 47.6 kg/m . The mean BMI max - 49.6 kg/m . There were no differences regarding education in both populations. Despite the lack of differences regarding changes in the BMI since withdrawal from treatment, as many as 63% of patients from rural areas reached the BMI max in this time. CONCLUSIONS: There were demographic differences between the degree of obesity observed among patients receiving bariatric treatment, and inhabitants of urban areas were favoured. Patients from rural areas who withdrew from bariatric treatment and were left without medical care significantly more often achieved their maximum body weight, when compared to those living in urban areas. The active participation of physicians, both specialists and general practitioners, in the life of obese patients is imperative.
[Mh] Termos MeSH primário: Bariatria/utilização
Obesidade/terapia
[Mh] Termos MeSH secundário: Adulto
Feminino
Seres Humanos
Masculino
Meia-Idade
Polônia
População Rural
Fatores Socioeconômicos
População Urbana
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170113
[Lr] Data última revisão:
170113
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161230
[St] Status:MEDLINE
[do] DOI:10.5604/12321966.1226867


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[PMID]:27571593
[Ti] Título:French comment on article: Trans-fistulary endoscopic drainage for post-bariatric abdominal collections communicating with the upper gastrointestinal tract.
[So] Source:Endoscopy;48(9):873-4, 2016 09.
[Is] ISSN:1438-8812
[Cp] País de publicação:Germany
[La] Idioma:eng
[Mh] Termos MeSH primário: Drenagem
Trato Gastrointestinal Superior
[Mh] Termos MeSH secundário: Abdome
Bariatria
Endoscopia
Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE; COMMENT
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170904
[Lr] Data última revisão:
170904
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160830
[St] Status:MEDLINE
[do] DOI:10.1055/s-0042-113567


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[PMID]:27352868
[Au] Autor:Gulland A
[Ad] Endereço:London.
[Ti] Título:Sixty seconds on . . . AspireAssist.
[So] Source:BMJ;353:i3540, 2016 Jun 28.
[Is] ISSN:1756-1833
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Bariatria/métodos
Terapia Nutricional
Obesidade/terapia
[Mh] Termos MeSH secundário: Seres Humanos
Terapia Nutricional/instrumentação
Terapia Nutricional/métodos
[Pt] Tipo de publicação:NEWS
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:160630
[St] Status:MEDLINE
[do] DOI:10.1136/bmj.i3540


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[PMID]:27234860
[Au] Autor:Kielczewska M; Szymczyk J; Leszczynski R; Blaszczyk J
[Ad] Endereço:Baltic Center of Plastic Surgery in Kolobrzeg, Poland.
[Ti] Título:[The effect of high-frequency current and ultrasonic wave on selected parameters of fat tissue].
[Ti] Título:Wplyw pradu wielkiej czestotliwosci i fali ultradzwiekowej na wybrane parametry gospodarki tluszczowej..
[So] Source:Pol Merkur Lekarski;40(239):298-300, 2016 May.
[Is] ISSN:1426-9686
[Cp] País de publicação:Poland
[La] Idioma:pol
[Ab] Resumo:UNLABELLED: Obesity and struggle with its consequences, also aesthetic type resulted in the growing development of methods of body shaping, contouring shapes, increasing skin firmness and skin tightening. The reason is the increasing in recent years, public demand, especially in developed countries. Development of aesthetic dermatology is driven by the search for therapeutic options with minimal invasiveness, enabling the reduction of excess body fat, to obtain a slim figure and reduce the laxity of the skin without the need for surgery. Current high frequency sound wave is an alternative method of treatment for patients with less severe defects. The continuous development of new technologies in the future will improve treatments for increasing the effectiveness and consistency of the results, while maintaining a favorable profile of the associated side effects. AIM: The aim of the study was to evaluate the behavior of the selected parameters of fat tissue in patients undergoing fat reduction BTL Exilis device. MATERIALS AND METHODS: The study included a 50-member group of women who are patients of the Specialist Clinic Al-Med in Kolobrzeg. Test was performed twice blood biochemical parameters before the first day of treatment and ten days after the fourth treatment. RESULTS: The results showed no statistical significance of the blood biochemical parameters in all subjects such as total cholesterol, LDL cholesterol, HDL cholesterol, triglycerides, and the activity of enzymes AST and ALT. CONCLUSIONS: No changes in biochemical parameters of lipid organism in the group of patients indicate the safety of therapy carried out by means of a device emitting high-frequency power and ultrasound. The treatment was evaluated by respondents as effective.
[Mh] Termos MeSH primário: Tecido Adiposo
Bariatria
Terapia por Estimulação Elétrica
Obesidade/terapia
Terapia por Ultrassom
[Mh] Termos MeSH secundário: Adulto
Alanina Transaminase/sangue
Aspartato Aminotransferases/sangue
Colesterol/sangue
Feminino
Seres Humanos
Obesidade/sangue
Triglicerídeos/sangue
[Pt] Tipo de publicação:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Triglycerides); 97C5T2UQ7J (Cholesterol); EC 2.6.1.1 (Aspartate Aminotransferases); EC 2.6.1.2 (Alanine Transaminase)
[Em] Mês de entrada:1608
[Cu] Atualização por classe:160528
[Lr] Data última revisão:
160528
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160529
[St] Status:MEDLINE



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