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  1 / 1119 MEDLINE  
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[PMID]:28747096
[Au] Autor:Gates MC; Hinds HJ; Dale A
[Ad] Endereço:a Institute of Veterinary, Animal and Biomedical Sciences , Massey University , Private Bag 11-222, Palmerston North 4442 , New Zealand.
[Ti] Título:Preliminary description of aging cats and dogs presented to a New Zealand first-opinion veterinary clinic at end-of-life.
[So] Source:N Z Vet J;65(6):313-317, 2017 Nov.
[Is] ISSN:1176-0710
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:AIMS To conduct a preliminary investigation into the chronic disease conditions and clinical signs present in aging New Zealand companion animals at end-of-life and to describe the timing, circumstances, and manner of death. METHODS The medical records database of a first-opinion, companion animal, veterinary practice in Auckland, New Zealand was searched to identify all canine and feline patients ≥7 years of age that were subjected to euthanasia or cremated in the period between July 2012-June 2014. The free-text medical notes were analysed for information on the circumstances surrounding the death, previous diagnoses of chronic disease conditions, and the presence of clinical signs associated with decreased quality-of-life at the time of euthanasia. RESULTS The median age at death was 15 (max 22) years for the 130 cats and 12 (max 17) years for the 68 dogs in the study sample. Euthanasia at the clinic was carried out for 119/130 (91%) cats and 62/68 (91%) dogs, with the remainder recorded as having an unassisted death. The frequency of deaths was highest during December for both cats and dogs. Cost was mentioned as an issue in the medical records for 39/181 (21.6%) patients that were subjected to euthanasia. At the time of euthanasia, 92/119 (77.3%) cats and 43/62 (69.4%) dogs were recorded as having >1 clinical sign associated with a decreased quality-of-life. Inappetence and non-specific decline were the two most commonly recorded clinical signs for both dogs and cats. Cardiovascular disease (44/130, 34%), renal failure (40/130, 31%), and malignant neoplasia (36/130, 28%) were the most common chronic disease conditions recorded for cats. Degenerative joint disease (22/68, 32%), malignant neoplasia (14/68, 21%), and cardiovascular disease (8/68, 12%) were the most common chronic disease conditions recorded for dogs. CONCLUSIONS AND CLINICAL RELEVANCE These preliminary findings highlight that aging companion animals in New Zealand frequently have chronic disease conditions and clinical signs that may potentially be associated with decreased quality-of-life at the time of death. Further in-depth studies are required to determine whether there is a greater role for veterinarians in counselling owners about end-of-life care and euthanasia decisions.
[Mh] Termos MeSH primário: Envelhecimento/fisiologia
Doenças do Gato/mortalidade
Gatos/fisiologia
Doenças do Cão/mortalidade
Cães/fisiologia
[Mh] Termos MeSH secundário: Animais
Causas de Morte
Eutanásia Animal
Hospitais Veterinários
Nova Zelândia
Médicos Veterinários
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171128
[Lr] Data última revisão:
171128
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170728
[St] Status:MEDLINE
[do] DOI:10.1080/00480169.2017.1360161


  2 / 1119 MEDLINE  
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[PMID]:28717108
[Au] Autor:Nakatsu N; Igarashi Y; Aoshi T; Hamaguchi I; Saito M; Mizukami T; Momose H; Ishii KJ; Yamada H
[Ad] Endereço:Toxicogenomics Informatics Project, National Institute of Biomedical Innovation, Health and Nutrition.
[Ti] Título:Isoflurane is a suitable alternative to ether for anesthetizing rats prior to euthanasia for gene expression analysis.
[So] Source:J Toxicol Sci;42(4):491-497, 2017.
[Is] ISSN:1880-3989
[Cp] País de publicação:Japan
[La] Idioma:eng
[Ab] Resumo:Diethyl ether (ether) had been widely used in Japan for anesthesia, despite its explosive properties and toxicity to both humans and animals. We also had used ether as an anesthetic for euthanizing rats for research in the Toxicogenomics Project (TGP). Because the use of ether for these purposes will likely cease, it is required to select an alternative anesthetic which is validated for consistency with existing TGP data acquired under ether anesthesia. We therefore compared two alternative anesthetic candidates, isoflurane and pentobarbital, with ether in terms of hematological findings, serum biochemical parameters, and gene expressions. As a result, few differences among the three agents were observed. In hematological and serum biochemistry analysis, no significant changes were found. In gene expression analysis, four known genes were extracted as differentially expressed genes in the liver of rats anesthetized with ether, isoflurane, or pentobarbital. However, no significant relationships were detected using gene ontology, pathway, or gene enrichment analyses by DAVID and TargetMine. Surprisingly, although it was expected that the lung would be affected by administration via inhalation, only one differentially expressed gene was extracted in the lung. Taken together, our data indicate that there are no significant differences among ether, isoflurane, and pentobarbital with respect to effects on hematological parameters, serum biochemistry parameters, and gene expression. Based on its smallest affect to existing data and its safety profile for humans and animals, we suggest isoflurane as a suitable alternative anesthetic for use in rat euthanasia in toxicogenomics analysis.
[Mh] Termos MeSH primário: Anestesia
Anestésicos Inalatórios
Éter
Eutanásia Animal
Isoflurano
Ratos Sprague-Dawley/sangue
Ratos Sprague-Dawley/genética
Transcriptoma
[Mh] Termos MeSH secundário: Anestésicos Inalatórios/toxicidade
Animais
Éter/toxicidade
Fígado
Pulmão
Masculino
Pentobarbital
Toxicogenética
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anesthetics, Inhalation); 0F5N573A2Y (Ether); CYS9AKD70P (Isoflurane); I4744080IR (Pentobarbital)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171005
[Lr] Data última revisão:
171005
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170719
[St] Status:MEDLINE
[do] DOI:10.2131/jts.42.491


  3 / 1119 MEDLINE  
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[PMID]:28555953
[Au] Autor:Arbe Montoya AI; Rand JS; Greer RM; Alberthsen C; Vankan D
[Ad] Endereço:School of Veterinary Science, The University of Queensland, Gatton 4343, Queensland, Australia.
[Ti] Título:Relationship between sources of pet acquisition and euthanasia of cats and dogs in an animal shelter: a pilot study.
[So] Source:Aust Vet J;95(6):194-200, 2017 Jun.
[Is] ISSN:1751-0813
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: Approximately 140,000 unwanted dogs and cats are culled in Australia annually. There is a paucity of information linking sources of pet acquisition with subsequent euthanasia, which may inform evidence-based strategies to reduce euthanasia rates. This pilot study aimed to determine whether there is a higher risk of euthanasia related to the source of acquisition for pets surrendered to an animal shelter. METHODS: Data for 5391 dogs and 5581 cats surrendered to one Queensland shelter between January 2006 and December 2009 were analysed. RESULTS: The main sources of acquisition for owner-surrendered dogs were 'shelter' and 'pet shop' and for owner-surrendered cats were 'own litter' and 'shelter'. Euthanasia rates for different sources varied. For adult dogs, acquisition through newspaper advertisements was associated with the highest euthanasia rate. Adult cats obtained as gifts (from friend or family member) had the highest euthanasia rate. For junior cats, the overwhelming source was the owner's own litter (68% of intake) and only kittens acquired as strays were at significantly higher risk of euthanasia. For both dogs and cats, animals acquired from shelters had lower rates of euthanasia than most other sources, which suggests that shelter-sourced animals may be considered a preferred source for pet acquisition to assist in reducing the number of adoptable pets euthanased. CONCLUSION: There was evidence from the study animal shelter that the risk of euthanasia was related to acquisition source. These findings should be confirmed by prospective studies, which should also investigate the interaction between acquisition source and other factors, using larger data sets from a variety of shelters.
[Mh] Termos MeSH primário: Gatos
Comércio/estatística & dados numéricos
Cães
Eutanásia Animal/estatística & dados numéricos
Propriedade/estatística & dados numéricos
[Mh] Termos MeSH secundário: Bem-Estar do Animal
Animais
Cruzamento
Bases de Dados Factuais
Doações
Abrigo para Animais
Jornais como Assunto
Projetos Piloto
Queensland
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171006
[Lr] Data última revisão:
171006
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170531
[St] Status:MEDLINE
[do] DOI:10.1111/avj.12582


  4 / 1119 MEDLINE  
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[PMID]:28555952
[Au] Autor:Degeling C; Fawcett A; Collins T; Hazel S; Johnson J; Lloyd J; Phillips C; Stafford K; Tzioumis V; McGreevy P
[Ad] Endereço:Centre for Values, Ethics and the Law in Medicine, The University of Sydney, New South Wales, Australia.
[Ti] Título:Students' opinions on welfare and ethics issues for companion animals in Australian and New Zealand veterinary schools.
[So] Source:Aust Vet J;95(6):189-193, 2017 Jun.
[Is] ISSN:1751-0813
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To determine what veterinary students in Australia and New Zealand consider important competences in companion animal welfare and ethics (AWE) required on their first day of practice, and to explore how their priorities relate to gender and stage of study. METHODS: Undergraduate students at all veterinary schools in Australia and New Zealand were sent an online survey. A subset of questions required participants to rank the importance of preselected AWE topics pertaining to companion animals. Data were analysed to determine differences in the way students of different gender or academic stage prioritised each of these AWE topics. RESULTS: Of 3220 currently enrolled students, 851 participated in the survey: 79% were female, 17% male, 4% unspecified. Ranking of the AWE topics, from highest to lowest importance, was: neutering, companion animal husbandry, euthanasia, behaviour and training, animal breeding, over-servicing in relation to animal needs and cosmetic surgery. Female students consistently ranked competency in AWE issues surrounding neutering more highly than male students (P = 0.006). Students in senior years of study ranked the importance of competency in animal abuse/hoarding (P = 0.048), shelter medicine (P = 0.012) and animal breeding (P = 0.002) less highly than those in junior years. CONCLUSIONS: Australasian veterinary students placed more importance on competency in AWE issues associated with clinical practice (such as neutering and euthanasia) than on professional behaviours (such as over-servicing and animal breeding). However, we consider that emphasis should still be placed on developing graduate competency in the latter categories to reflect growing societal concerns about companion animal over-supply and inappropriate professional conduct.
[Mh] Termos MeSH primário: Criação de Animais Domésticos
Bem-Estar do Animal
Atitude
Estudantes/psicologia
[Mh] Termos MeSH secundário: Criação de Animais Domésticos/ética
Bem-Estar do Animal/ética
Animais
Austrália
Competência Clínica
Eutanásia Animal
Feminino
Seres Humanos
Internet
Masculino
Nova Zelândia
Animais de Estimação
Faculdades de Medicina Veterinária
Distribuição por Sexo
Esterilização Reprodutiva/psicologia
Esterilização Reprodutiva/veterinária
Inquéritos e Questionários
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171006
[Lr] Data última revisão:
171006
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170531
[St] Status:MEDLINE
[do] DOI:10.1111/avj.12590


  5 / 1119 MEDLINE  
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[PMID]:28535865
[Au] Autor:de Souza Dyer C; Brice AK; Marx JO
[Ad] Endereço:University Laboratory Animal Resources, Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
[Ti] Título:Intraperitoneal Administration of Ethanol as a Means of Euthanasia for Neonatal Mice ( ).
[So] Source:J Am Assoc Lab Anim Sci;56(3):299-306, 2017 May 01.
[Is] ISSN:1559-6109
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The humane euthanasia of animals in research is of paramount importance. Neonatal mice frequently respond differently to euthanasia agents when compared with adults. The AVMA's Guidelines for the Euthanasia of Animals includes intraperitoneal injection of ethanol as "acceptable with conditions," and recent work confirmed that this method is appropriate for euthanizing adult mice, but neonatal mice have not been tested. To explore this method in neonatal mice, mouse pups (C57BL/6 and CD1, 162 total) were injected with 100% ethanol, a pentobarbital-phenytoin combination, or saline at 7, 14, 21, 28, or 35 d of age. Electrocardiograms, respiratory rates, and times to loss of righting reflex and death were recorded. Time to death (TTD) differed significantly between ethanol and pentobarbital-phenytoin at 7, 14, and 21 d and between ethanol groups at 7, 14, and 21 d compared with 35 d. The average TTD (± 1 SD) for ethanol-injected mice were: 7 d, 70.3 ± 39.8 min; 14 d, 51.7 ± 30.5 min; 21 d, 32.3 ± 20.8 min, 28 d, 14.0 ± 15.2; and 35 d, 4.9 ± 1.4. Mean TTD in pentobarbital-phenytoin-injected mice were: 7 d, 2.8 ± 0.4 min; 14 d, 2.9 ± 0.5 min; 21 d, 3.9 ± 1.2 min; 28 d, 3.9 ± 0.7 min; and 35 d, 4.4 ± 0.5. Although TTD did not differ between ethanol and pentobarbital-phenytoin at 28 d of age, the TTD in 3 of 12 mice was longer than 15 min after ethanol administration at this age. Therefore, ethanol should not be used as a method of euthanasia for mice younger than 35 d, because the criteria for humane euthanasia were met only in mice 35 d or older.
[Mh] Termos MeSH primário: Animais Recém-Nascidos
Etanol/administração & dosagem
Eutanásia Animal/métodos
Camundongos
[Mh] Termos MeSH secundário: Bem-Estar do Animal
Animais
Injeções Intraperitoneais
Camundongos Endogâmicos C57BL
Pentobarbital/administração & dosagem
Fenitoína/administração & dosagem
Inconsciência/induzido quimicamente
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
3K9958V90M (Ethanol); 6158TKW0C5 (Phenytoin); I4744080IR (Pentobarbital)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:171101
[Lr] Data última revisão:
171101
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170525
[St] Status:MEDLINE


  6 / 1119 MEDLINE  
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[PMID]:28475485
[Au] Autor:Kaupp G; Mitchell K
[Ad] Endereço:Equine Department, Vetsuisse Faculty, University of Zurich.
[Ti] Título:Ultrasound diagnosis of a diaphragmatic hernia in a 23-year-old Hanoverian gelding.
[So] Source:Schweiz Arch Tierheilkd;159(5):301-304, 2017 May.
[Is] ISSN:0036-7281
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Mh] Termos MeSH primário: Hérnia Diafragmática/veterinária
Doenças dos Cavalos/diagnóstico por imagem
[Mh] Termos MeSH secundário: Dor Abdominal
Animais
Eutanásia Animal
Hérnia Diafragmática/diagnóstico por imagem
Hérnia Diafragmática/fisiopatologia
Doenças dos Cavalos/fisiopatologia
Cavalos
Masculino
Ultrassonografia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170914
[Lr] Data última revisão:
170914
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170506
[St] Status:MEDLINE
[do] DOI:10.17236/sat00117


  7 / 1119 MEDLINE  
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[PMID]:28380586
[Au] Autor:Rault JL; Holyoake T; Coleman G
[Ti] Título:Stockperson attitudes toward pig euthanasia.
[So] Source:J Anim Sci;95(2):949-957, 2017 Feb.
[Is] ISSN:1525-3163
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Euthanasia is a necessary act for any facility keeping live animals. Nevertheless, the crucial role and responsibility of the stockperson in deciding and conducting on-farm euthanasia has been overlooked. Stockperson characteristics and knowledge that lead to appropriate decision-making and the skills to competently perform the procedure remain to be identified. An important component of the stockperson's characteristics that predict behavior is the stockperson's attitudes. This preliminary study investigated the factors that influence stockperson attitudes toward the practice of on-farm euthanasia in the pork industry. A total of 120 stockpeople from 10 Australian pig farms (ranging in size from 50 to 4,754 sows and from 2 to 32 employees) completed a questionnaire based on focus group input to assess their attitudes toward euthanasia and decision processes. Factors identified included stockperson attitudes and attributes (empathy affect, empathy attribution, feeling bad about euthanizing, and negative attitudes to pigs), beliefs about the working environment (perceived time constraints and relying on others), and factors related to decision-making (comfortable with euthanasia, trouble deciding and avoid if possible, confidence, insufficient knowledge, seeking knowledge, and using sources to get advice). Numerous significant correlations were found between these variables. Furthermore, regression analyses showed confidence as the only significant predictor of being comfortable with euthanasia (12.5% of the variance; < 0.001); insufficient knowledge and empathy attribution both as predictors of trouble deciding and avoid if possible (15.1% of the variance; = 0.001 and = 0.032, respectively); and empathy affect, insufficient knowledge, and perceived time constraints as predictors of feeling bad about euthanizing (23.2% of the variance; < 0.001, = 0.006, and = 0.022, respectively). Stockpeople reported seeking more knowledge if they had not euthanized an animal before working with pigs ( = 0.05), and women reported greater difficulty than men in conducting euthanasia ( < 0.01). The findings indicate that euthanasia, which comprises both a decision-making process and the act itself, can adversely affect stockpeople. This preliminary study offers insights for implementation of successful practical and humane pig euthanasia protocols on farm. This will benefit stockperson well-being and animal well-being alike.
[Mh] Termos MeSH primário: Atitude
Eutanásia Animal
Suínos
[Mh] Termos MeSH secundário: Criação de Animais Domésticos/métodos
Animais
Austrália
Coleta de Dados
Emoções
Feminino
Seres Humanos
Masculino
Gravidez
Análise de Regressão
Comportamento Social
Inquéritos e Questionários
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170707
[Lr] Data última revisão:
170707
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170406
[St] Status:MEDLINE
[do] DOI:10.2527/jas.2016.0922


  8 / 1119 MEDLINE  
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[PMID]:28376865
[Au] Autor:Yadav S; Weng HY
[Ad] Endereço:Department of Comparative Pathobiology, Purdue University, 625 Harrison Street, West Lafayette, IN, 47907, USA.
[Ti] Título:Estimating the scale of adverse animal welfare consequences of movement restriction and mitigation strategies in a classical swine fever outbreak.
[So] Source:BMC Vet Res;13(1):83, 2017 Apr 04.
[Is] ISSN:1746-6148
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The study aim was to quantify the impact of movement restriction on the well-being of pigs and the associated mitigation responses during a classical swine fever (CSF) outbreak. We developed a stochastic risk assessment model and incorporated Indiana swine industry statistics to estimate the timing and number of swine premises that would encounter overcrowding or feed interruption resulting from movement restriction. Our model also quantified the amount of on-farm euthanasia and movement of pigs to slaughter plants required to alleviate those conditions. We simulated various single-site (i.e., an outbreak initiated from one location) and multiple-site (i.e., an outbreak initiated from more than one location) outbreak scenarios in Indiana to estimate outputs. RESULTS: The study estimated that 14% of the swine premises in Indiana would encounter overcrowding or feed interruption due to movement restriction implemented during a CSF outbreak. The number of premises that would experience animal welfare conditions was about 2.5 fold of the number of infected premises. On-farm euthanasia needed to be performed on 33% of those swine premises to alleviate adverse animal welfare conditions, and more than 90% of on-farm euthanasia had to be carried out within 2 weeks after the implementation of movement restriction. Conversely, movement of pigs to slaughter plants could alleviate 67% of adverse animal welfare conditions due to movement restriction, and only less than 1% of movement of pigs to slaughter plants had to be initiated in the first 2 weeks of movement restrictions. The risk of secondary outbreaks due to movement of pigs from movement restriction areas to slaughter plants was low and only seven pigs from each shipment needed to be tested for CSF infection to prevent a secondary outbreak. CONCLUSIONS: We found that the scale of adverse animal welfare consequences of movement restriction during a CSF outbreak in Indiana was substantial, and controlled movement of pigs to slaughter plants was an efficient and low-risk alternative mitigation response to on-farm euthanasia. The output estimates generated from this study provide empirical evidence for decision makers to properly incorporate required resources for mitigating adverse animal welfare conditions in CSF outbreak management strategic planning.
[Mh] Termos MeSH primário: Bem-Estar do Animal
Peste Suína Clássica/prevenção & controle
Surtos de Doenças/veterinária
[Mh] Termos MeSH secundário: Matadouros
Criação de Animais Domésticos/métodos
Animais
Controle de Doenças Transmissíveis/métodos
Surtos de Doenças/prevenção & controle
Eutanásia Animal
Indiana/epidemiologia
Medição de Risco
Suínos
Transportes
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170919
[Lr] Data última revisão:
170919
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170406
[St] Status:MEDLINE
[do] DOI:10.1186/s12917-017-1008-5


  9 / 1119 MEDLINE  
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[PMID]:28364832
[Au] Autor:Lynch H; Leonard FC; Walia K; Lawlor PG; Duffy G; Fanning S; Markey BK; Brady C; Gardiner GE; Argüello H
[Ad] Endereço:National Food Research Centre, Teagasc, Ashtown, Dublin, Ireland; UCD Veterinary Sciences Centre, University College Dublin, Dublin, Ireland. Electronic address: Lynchhelen28@gmail.com.
[Ti] Título:Investigation of in-feed organic acids as a low cost strategy to combat Salmonella in grower pigs.
[So] Source:Prev Vet Med;139(Pt A):50-57, 2017 Apr 01.
[Is] ISSN:1873-1716
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Salmonella carriage in pigs is a significant food safety issue. Dietary supplementation with organic acids has previously been shown to reduce shedding and transmission of Salmonella. Therefore, this study aimed to examine the effect of three commercially available organic acid-based products on Salmonella levels in grower pigs, using a model of experimental infection that closely mimics natural exposure to the organism. Seven week old trial pigs (n=40) with a mean weight of 14.7kg were placed in one of four pens with 10 pigs/pen. Pens had previously been contaminated with Salmonella Typhimurium 4,[5],12;i;- via seeder pigs. Trial pigs received one of four diets for 28days: 1, control diet; 2, sodium butyrate supplemented diet; 3, benzoic acid supplemented diet and 4, formic-citric acid supplemented diet. A further 10 pigs were placed in a Salmonella-free pen receiving the control diet. Pigs were weighed and blood sampled on days 0 and 28. Faeces was collected on day 0, 2, 3, 5, 7, 14, 21 and 28 and examined for Salmonella. On day 28, 5 pigs/group were euthanised and ileocaecal lymph nodes (ILN) and caecal contents sampled for culture. The remaining 5 pigs/pen were then fed the control diet and faeces were collected on days 35 and 42. On day 42 pigs were euthanised and ILN and caecal contents tested for Salmonella levels. The trial was repeated once. Within the first two days of exposure to the contaminated environment, 96% (77/80) of pigs became infected. Most pigs shed Salmonella at levels of between 10 -10 CFU/g faeces for at least 7days post-exposure. A significant reduction in Salmonella faecal concentration was observed after supplementation with sodium butyrate (p=0.001) and a formic citric acid blend (p<0.0001). Average daily weight gain (ADWG) was significantly increased in all groups fed the supplemented feed when compared to the positive control group. The use of sodium butyrate or a blend of formic and citric acid in feed could be considered a cost-effective control measure to reduce Salmonella faecal shedding and improve ADWG in Salmonella infected herds.
[Mh] Termos MeSH primário: Ração Animal
Ácido Butírico/administração & dosagem
Ácido Cítrico/administração & dosagem
Formiatos/administração & dosagem
Salmonelose Animal/prevenção & controle
Doenças dos Suínos/prevenção & controle
[Mh] Termos MeSH secundário: Análise de Variância
Animais
Derrame de Bactérias/efeitos dos fármacos
Ácido Benzoico/administração & dosagem
Ceco/microbiologia
Suplementos Nutricionais
Eutanásia Animal
Fezes/microbiologia
Distribuição Aleatória
Salmonelose Animal/sangue
Salmonella typhimurium/isolamento & purificação
Suínos
Doenças dos Suínos/sangue
Doenças dos Suínos/microbiologia
Ganho de Peso
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Formates); 0YIW783RG1 (formic acid); 107-92-6 (Butyric Acid); 2968PHW8QP (Citric Acid); 8SKN0B0MIM (Benzoic Acid)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170821
[Lr] Data última revisão:
170821
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170403
[St] Status:MEDLINE


  10 / 1119 MEDLINE  
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[PMID]:28364828
[Au] Autor:Mõtus K; Reimus K; Orro T; Viltrop A; Emanuelson U
[Ad] Endereço:Institute of Veterinary Medicine and Animal Sciences, Estonian University of Life Sciences, Estonia. Electronic address: Kerli.Motus@emu.ee.
[Ti] Título:On-farm mortality, causes and risk factors in Estonian beef cow-calf herds.
[So] Source:Prev Vet Med;139(Pt A):10-19, 2017 Apr 01.
[Is] ISSN:1873-1716
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:High on-farm mortality is associated with lower financial return of production and poor animal health and welfare. Understanding the reasons for on-farm mortality and related risk factors allows focus on specific prevention measures. This retrospective cohort study used cattle registry data from the years 2013 and 2014, collected from cattle from all Estonian cow-calf beef herds. The dataset contained 78,605 animal records from 1321 farms in total. Including unassisted deaths and euthanasia (2199 in total) the on-farm mortality rate was 2.14 per 100 animal-years. Across all age groups of both sexes the mortality rate (MR) was highest for bull calves up to three months old (MR=7.78 per 100 animal-years, 95% CI 6.97; 8.68) followed by that for heifer calves (MR=6.21 per 100 animal-years, 95% CI 5.49; 7.02). For female cattle the mortality risk declined after three months of age but increased again among animals over 18 months. The reason for death stated by the farmers was analysed for cattle under animal performance testing. Other/unknown reasons, trauma and accidents, as well as metabolic and digestive disorders, formed the three most commonly reported reasons for death in cattle of all age groups. Weibull proportional hazard models with farm frailty effects were applied in three age categories (calves up to three months, youngstock from three to 18 months and cattle aged over 18 months) to identify factors associated with the risk of mortality. Male sex was associated with increased risk of mortality in cattle up to 18 months of age. No difference between breeds was found for cattle up to 18 months of age. Beef cattle breeds rarely represented or dairy breeds (breed category 'Other') had the highest mortality hazard (HR=1.41, 95% CI 1.11; 1.78) compared to Hereford. The hazard of mortality generally increased with herd size for calves, young stock and older bulls. In female cattle over 18 months of age there was no difference in mortality hazard over herd size categories. Herd location was controlled in the models and regional differences in mortality hazard were found. Common to all age groups, calving season was associated with increased risk of mortality.
[Mh] Termos MeSH primário: Doenças dos Bovinos/mortalidade
[Mh] Termos MeSH secundário: Criação de Animais Domésticos
Animais
Bovinos
Doenças dos Bovinos/epidemiologia
Causas de Morte
Estônia/epidemiologia
Eutanásia Animal/estatística & dados numéricos
Fazendas
Feminino
Masculino
Modelos de Riscos Proporcionais
Sistema de Registros
Estudos Retrospectivos
Fatores de Risco
Estações do Ano
Distribuição por Sexo
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170821
[Lr] Data última revisão:
170821
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170403
[St] Status:MEDLINE



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