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  1 / 19563 MEDLINE  
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[PMID]:29384600
[Au] Autor:Kondov S; Siepe M; Beyersdorf F; von Samson-Himmelstjern P; Czerny M
[Ad] Endereço:Department of Cardiovascular Surgery, University Heart Center Freiburg, Faculty of Medicine, University of Freiburg, Germany.
[Ti] Título:Thoracoabdominal aortic replacement with a bovine pericardial tube graft for aortobronchial fistulation 10 years after TEVAR.
[So] Source:Multimed Man Cardiothorac Surg;2017, 2017 Dec 20.
[Is] ISSN:1813-9175
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Aortobronchial fistula after thoracic endovascular aortic repair is usually a late complication. It is associated with high mortality and its surgical management is technically challenging. This tutorial illustrates the steps involved in removing an infected stent graft and replacing it with a bovine pericardial tube graft.
[Mh] Termos MeSH primário: Aneurisma da Aorta Torácica/cirurgia
Doenças da Aorta/cirurgia
Implante de Prótese Vascular/efeitos adversos
Fístula Brônquica/cirurgia
Infecções Relacionadas à Prótese/cirurgia
Fístula Vascular/cirurgia
[Mh] Termos MeSH secundário: Animais
Doenças da Aorta/etiologia
Bioprótese
Prótese Vascular/efeitos adversos
Fístula Brônquica/etiologia
Bovinos
Remoção de Dispositivo
Procedimentos Endovasculares/efeitos adversos
Seres Humanos
Pericárdio/transplante
Infecções Relacionadas à Prótese/etiologia
Reoperação
Stents/efeitos adversos
Fístula Vascular/etiologia
[Pt] Tipo de publicação:VIDEO-AUDIO MEDIA
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180201
[St] Status:MEDLINE
[do] DOI:10.1510/mmcts.2017.027


  2 / 19563 MEDLINE  
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[PMID]:28453796
[Au] Autor:Kondov S; Rylski B; Kari FA; Wobser R; Leschka S; Siepe M; Beyersdorf F; Czerny M
[Ad] Endereço:Department of Cardiovascular Surgery, University Heart Center Freiburg-Bad Krozingen, Freiburg, Germany.
[Ti] Título:Descendo-bifemoral bypass grafting and renal artery revascularization to treat complex obliterative arteriopathy.
[So] Source:Interact Cardiovasc Thorac Surg;24(5):655-658, 2017 05 01.
[Is] ISSN:1569-9285
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: Our goal was to describe a new standardized approach in patients with extensive obliterative arteriopathy aimed at distal revascularization and surgical kidney recruitment via descendo-bifemoral bypass grafting and renal artery revascularization. METHODS: Three patients with Leriche's syndrome and either a compromised single kidney or unilateral significant renal artery stenosis were treated with a standardized surgical approach, restoration of distal perfusion via descendo-bifemoral bypass with synchronous ( n = 2) left-sided renal artery revascularization or metachronous ( n = 1) right-sided renal artery revascularization. RESULTS: The intended surgical aim was achieved successfully in all 3 cases. All patients showed a decline in serum creatinine levels. One patient who needed substitution therapy was free from dialysis 3 months after surgery. Additionally, blood pressure management was substantially reduced because uncontrolled peak systolic episodes were no longer observed and pharmacotherapeutic agents could be partially withdrawn. CONCLUSIONS: Distal revascularization and surgical kidney recruitment via descendo-bifemoral bypass and renal artery revascularization is a promising option to treat complex obliterative arteriopathy.
[Mh] Termos MeSH primário: Aorta Abdominal/cirurgia
Implante de Prótese Vascular/métodos
Artéria Femoral/cirurgia
Rim/irrigação sanguínea
Síndrome de Leriche/cirurgia
Obstrução da Artéria Renal/cirurgia
Artéria Renal/cirurgia
[Mh] Termos MeSH secundário: Anastomose Cirúrgica/métodos
Angiografia por Tomografia Computadorizada
Feminino
Seres Humanos
Síndrome de Leriche/complicações
Síndrome de Leriche/diagnóstico
Masculino
Meia-Idade
Obstrução da Artéria Renal/diagnóstico
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170429
[St] Status:MEDLINE
[do] DOI:10.1093/icvts/ivw388


  3 / 19563 MEDLINE  
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[PMID]:29300074
[Au] Autor:Schneider A; Klautz RJM; Hazekamp M
[Ad] Endereço:Department of Cardiothoracic Surgery Leiden University Medical Center Leiden, The Netherlands.
[Ti] Título:The Ross reimplantation technique.
[So] Source:Multimed Man Cardiothorac Surg;2017, 2017 Sep 25.
[Is] ISSN:1813-9175
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Pulmonary autograft replacement of a diseased aortic valve (the Ross procedure) is effective in children, where growth is essential, and in young patients for whom a biological solution is preferred. Long-term outcomes are generally good. However eventual autograft dilatation may necessitate reoperation. In order to diminish the risk of autograft dilatation, several 'wrapping' techniques have been developed. Here, we present our technique of choice: the reimplantation of the pulmonary autograft in a vascular tube graft, scalloping the sinuses of Valsalva. This leaves no bulky tissue inside the vascular tube graft and makes autograft dilatation impossible.
[Mh] Termos MeSH primário: Valva Aórtica/cirurgia
Implante de Prótese de Valva Cardíaca/métodos
[Mh] Termos MeSH secundário: Bioprótese
Implante de Prótese Vascular
Seres Humanos
Reoperação
Reimplante
Seio Aórtico/cirurgia
Transplante Autólogo
[Pt] Tipo de publicação:VIDEO-AUDIO MEDIA
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180302
[Lr] Data última revisão:
180302
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180105
[St] Status:MEDLINE
[do] DOI:10.1510/mmcts.2017.019


  4 / 19563 MEDLINE  
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[PMID]:29390289
[Au] Autor:Wei XQ; Song L; Zhang XS; Wang KY; Wu J
[Ad] Endereço:Interventional Therapy Department, The Second Hospital of Dalian Medical University, Dalian, China.
[Ti] Título:Endovascular stent graft repair of aortogastric fistula caused by peptic ulcer after esophagectomy: A case report.
[So] Source:Medicine (Baltimore);96(50):e8959, 2017 Dec.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RATIONALE: Aortogastric fistula (AGF) is a rare but devastating clinical complication after esophagectomy. In a recent report, nearly all AGF patients died of massive hemorrhage or aspiration of massive hematemesis. Therefore, timely appropriate treatment of AGF remains a challenge.Herein, we report a case of AGF that resulted from peptic ulceration after esophagectomy and was successfully treated with endovascular stent graft placement. PATIENT CONCERNS: A 59-year-old man had undergone video-assisted thoracoscopic esophagectomy for squamous cell carcinoma and esophageal reconstruction using a gastric tube 14 months previously. He suddenly experienced massive hematemesis and unstable circulatory dynamics, Infusion was performed to treat critical hemorrhagic shock but was ineffective. We informed the patient and his family members of the situation, and once written informed consent to treatment was provided, we rushed him to the operating room. DIAGNOSES: Contrast medium permeated into the gastric cavity through a fistula between the abdominal aorta and gastric tube at the 11th thoracic level, Based on this, we made a diagnosis of AGF resulting from a peptic ulcer, and this diagnosis was further confirmed by high pressure angiography combined with computed tomography (CT) imaging. INTERVENTIONS: An endovascular stent graft was placed under the guidance of digital subtraction angiography and followed by antibiotic therapy to prevent infection and proton pump inhibitor therapy to inhibit gastric acid secretion. OUTCOMES: The patient recovered uneventfully after the procedure. Four months after surgery, the patient died of organ failure caused by retroperitoneal lymph node metastasis and multiple intrahepatic metastases, with no postoperative bleeding linked to the endovascular stent graft repair. LESSONS: Our case supports the notion that endovascular stent graft repair is a feasible alternative in treatment of AGF with several advantages in addition to surgical intervention, although more such cases should be collected and analyzed in the future to corroborate our observations.
[Mh] Termos MeSH primário: Doenças da Aorta/terapia
Procedimentos Endovasculares
Esofagectomia
Fístula Gástrica/terapia
Úlcera Péptica/cirurgia
Complicações Pós-Operatórias/terapia
Stents
Fístula Vascular/terapia
[Mh] Termos MeSH secundário: Doenças da Aorta/diagnóstico por imagem
Prótese Vascular
Implante de Prótese Vascular
Extravasamento de Materiais Terapêuticos e Diagnósticos
Evolução Fatal
Fístula Gástrica/diagnóstico por imagem
Seres Humanos
Masculino
Meia-Idade
Complicações Pós-Operatórias/diagnóstico por imagem
Cirurgia Torácica Vídeoassistida
Tomografia Computadorizada por Raios X
Fístula Vascular/diagnóstico por imagem
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180301
[Lr] Data última revisão:
180301
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180203
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000008959


  5 / 19563 MEDLINE  
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[PMID]:29320978
[Au] Autor:Lim CS; Dhutia A; Riga C; Dharmadasa A; Gibbs RGJ; Hamady MS
[Ad] Endereço:1 Regional Vascular Unit, St Mary's Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom.
[Ti] Título:Two-Vessel Branched Stent Graft for Severely Angulated Aortic Arch Aneurysm in a Jehovah's Witness.
[So] Source:Vasc Endovascular Surg;52(2):154-158, 2018 Feb.
[Is] ISSN:1938-9116
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Aneurysmal disease involving the origins of supra aortic vessels often requires complex open and/or endovascular repair that is not only associated with significant risk of mortality and morbidity but also often with perioperative blood loss requiring transfusion. We report a successful repair of a large thoracic aortic aneurysm (TAA) involving the aortic arch with a custom-made Bolton Relay 2-vessel branched thoracic aortic endograft in a 42-year-old Jehovah's Witness who would otherwise be very unlikely to survive an open repair. Branched thoracic aortic endografting offers a potentially safe, minimally invasive, and effective alternative for TAA disease involving the supra-aortic arteries, especially in patients who are at high risk of open surgery.
[Mh] Termos MeSH primário: Aneurisma da Aorta Torácica/cirurgia
Perda Sanguínea Cirúrgica/prevenção & controle
Implante de Prótese Vascular/instrumentação
Prótese Vascular
Procedimentos Endovasculares/instrumentação
Testemunhas de Jeová
Religião e Medicina
Stents
[Mh] Termos MeSH secundário: Adulto
Angiografia Digital
Aneurisma da Aorta Torácica/diagnóstico por imagem
Aortografia/métodos
Transfusão de Sangue
Angiografia por Tomografia Computadorizada
Seres Humanos
Masculino
Desenho de Prótese
Resultado do Tratamento
Recusa do Paciente ao Tratamento
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180228
[Lr] Data última revisão:
180228
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180112
[St] Status:MEDLINE
[do] DOI:10.1177/1538574417747426


  6 / 19563 MEDLINE  
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[PMID]:29246081
[Au] Autor:Garriboli L; Jannello AM
[Ad] Endereço:1 Department of Vascular Surgery, H. Sacro Cuore Don Calabria, Negrar VR, Italy.
[Ti] Título:Uncovered Chimney Stent Graft for Renal Arteries With the Nellix Endovascular Aneurysm Sealing Technique.
[So] Source:Vasc Endovascular Surg;52(2):148-153, 2018 Feb.
[Is] ISSN:1938-9116
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PURPOSE: To describe the application of uncovered chimney stent grafts with the Nellix endovascular aneurysm sealing technique (ChEVAS) for juxtarenal abdominal aortic aneurysms (JAAAs). CASE REPORT: Two patients with JAAA and multiple comorbidities were considered unfit for open surgery and were selected for an endovascular approach. Fenestrated and branched endografts were too expensive, and a chimney endovascular approach was considered inappropriate for the relatively high incidence of proximal type I endoleak and graft migration. ChEVAS was performed successfully with the novel addition of uncovered chimney stents to further reduce costs and possibly improve target vessel patency. JAAA exclusion and visceral vessel patency was confirmed at 18-month follow-up. CONCLUSION: ChEVAS with bare chimney stents is technically less complex, potentially reduces access complications and procedural costs, and may improve long-term patency compared to alternative techniques. Results at 18 months seem promising, but strict follow-up is necessary as the long-term durability is unknown.
[Mh] Termos MeSH primário: Aorta Abdominal/cirurgia
Aneurisma da Aorta Abdominal/cirurgia
Implante de Prótese Vascular/instrumentação
Prótese Vascular
Procedimentos Endovasculares/instrumentação
Artéria Renal/cirurgia
Stents
[Mh] Termos MeSH secundário: Idoso de 80 Anos ou mais
Aorta Abdominal/diagnóstico por imagem
Aneurisma da Aorta Abdominal/diagnóstico por imagem
Aortografia/métodos
Angiografia por Tomografia Computadorizada
Seres Humanos
Masculino
Meia-Idade
Desenho de Prótese
Artéria Renal/diagnóstico por imagem
Resultado do Tratamento
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180228
[Lr] Data última revisão:
180228
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171217
[St] Status:MEDLINE
[do] DOI:10.1177/1538574417747175


  7 / 19563 MEDLINE  
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[PMID]:29237361
[Au] Autor:Rogers MP; Reskin SM; Ubert A; Black MC; Grubb KJ
[Ad] Endereço:1 Department of Cardiovascular and Thoracic Surgery, University of Louisville School of Medicine, Louisville, KY, USA.
[Ti] Título:Hybrid Endovascular Aortic Arch Reconstruction for Acute Aortic Dissection: An Endovascular Bridge Technique for Complex Anatomy.
[So] Source:Vasc Endovascular Surg;52(2):143-147, 2018 Feb.
[Is] ISSN:1938-9116
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Acute type A aortic dissections starting at the arch pose a challenge for cardiac surgeons. Open surgical repair requires deep hypothermic circulatory arrest for arch reconstruction and is associated with significant morbidity and mortality. Hybrid aortic repair techniques, with open arch debranching and thoracic endovascular aortic repair, have been employed in high-risk cases and challenging aortic pathology. Herein, we present a case of a 33-year-old African American male with a history of open thoracoabdominal aortic reconstruction and femoral-femoral artery bypass for a type B dissection who subsequently presented with new-onset chest pain and was found to have a retrograde type A dissection of a bovine arch with multiple dissection flaps and possible contrast extravasation on chest computed tomography. Endovascular reconstruction of the aortic arch using a hybrid technique was utilized and proved to be feasible and further should be considered when complex anatomy limits traditional surgical options.
[Mh] Termos MeSH primário: Aneurisma Dissecante/cirurgia
Aorta Torácica/cirurgia
Aneurisma da Aorta Torácica/cirurgia
Implante de Prótese Vascular/métodos
Procedimentos Endovasculares/métodos
[Mh] Termos MeSH secundário: Doença Aguda
Adulto
Aneurisma Dissecante/diagnóstico por imagem
Aneurisma Dissecante/fisiopatologia
Aorta Torácica/anormalidades
Aorta Torácica/diagnóstico por imagem
Aorta Torácica/fisiopatologia
Aneurisma da Aorta Torácica/diagnóstico por imagem
Aneurisma da Aorta Torácica/fisiopatologia
Aortografia/métodos
Implante de Prótese Vascular/instrumentação
Angiografia por Tomografia Computadorizada
Procedimentos Endovasculares/instrumentação
Hemodinâmica
Seres Humanos
Masculino
Resultado do Tratamento
Ultrassonografia de Intervenção
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180228
[Lr] Data última revisão:
180228
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171215
[St] Status:MEDLINE
[do] DOI:10.1177/1538574417747037


  8 / 19563 MEDLINE  
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[PMID]:29202650
[Au] Autor:Wrede A; Wiberg F; Acosta S
[Ad] Endereço:These authors contributed equally to this work.
[Ti] Título:Increasing the Elective Endovascular to Open Repair Ratio of Popliteal Artery Aneurysm.
[So] Source:Vasc Endovascular Surg;52(2):115-123, 2018 Feb.
[Is] ISSN:1938-9116
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Open repair (OR) for popliteal artery aneurysm (PAA) has recently been challenged by endovascular repair (ER) as the primary choice of treatment. The aim of the present study was to evaluate time trends in treatment modality and compare outcomes between OR and ER among electively operated patients after start of screening in 2010 for abdominal aortic aneurysm (AAA), a disease highly associated with PAA. METHODS: Between January 1, 2009, and April 30, 2017, 102 procedures and 36 acute and 66 elective repairs for PAA were identified. RESULTS: Over time, a trend ( P = .089) for an increasing elective to acute repair ratio of PAA and an increase in elective ER to OR ratio ( P = .003) was found. Among electively repaired PAAs, the ER group was older ( P = .047) and had a higher ankle-brachial index (ABI; P = .044). The ER group had fewer wound infections ( P = .003), fewer major bleeding complications ( P = .046), and shorter in-hospital stay ( P < .001). After 1 year of follow-up, the ER group had a higher rate of major amputations ( P = .037). Amputation-free survival at the end of follow-up did not differ between groups ( P = .68). Among the 17 patients with PAA eligible for AAA screening, 4 (24%) were diagnosed with PAA through the screening program of AAA. CONCLUSION: The epidemiology of elective repair of PAA has changed toward increased ER, although ER showed a higher rate of major amputations at 1 year. Confounding was considerable and a randomized trial is needed for evaluation of the best therapeutic option.
[Mh] Termos MeSH primário: Aneurisma/cirurgia
Implante de Prótese Vascular
Procedimentos Endovasculares
Artéria Poplítea/cirurgia
Veia Safena/transplante
[Mh] Termos MeSH secundário: Idoso
Idoso de 80 Anos ou mais
Amputação
Aneurisma/diagnóstico por imagem
Aneurisma/epidemiologia
Implante de Prótese Vascular/efeitos adversos
Implante de Prótese Vascular/tendências
Procedimentos Cirúrgicos Eletivos
Procedimentos Endovasculares/efeitos adversos
Procedimentos Endovasculares/tendências
Feminino
Seres Humanos
Salvamento de Membro
Masculino
Meia-Idade
Artéria Poplítea/diagnóstico por imagem
Complicações Pós-Operatórias/etiologia
Estudos Retrospectivos
Fatores de Risco
Suécia/epidemiologia
Fatores de Tempo
Resultado do Tratamento
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; OBSERVATIONAL STUDY
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180228
[Lr] Data última revisão:
180228
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171206
[St] Status:MEDLINE
[do] DOI:10.1177/1538574417742762


  9 / 19563 MEDLINE  
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[PMID]:28457427
[Au] Autor:Chong AY; Doyle BJ; Jansen S; Ponosh S; Cisonni J; Sun Z
[Ad] Endereço:Department of Medical Radiation Sciences, Curtin University, Perth, Australia.
[Ti] Título:Blood flow velocity prediction in aorto-iliac stent grafts using computational fluid dynamics and Taguchi method.
[So] Source:Comput Biol Med;84:235-246, 2017 May 01.
[Is] ISSN:1879-0534
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Covered Endovascular Reconstruction of Aortic Bifurcation (CERAB) is a new technique to treat extensive aortoiliac occlusive disease with covered expandable stent grafts to rebuild the aortoiliac bifurcation. Post stenting Doppler ultrasound (DUS) measurement of maximum peak systolic velocity (PSV ) in the stented segment is widely used to determine patency and for follow up surveillance due to the portability, affordability and ease of use. Anecdotally, changes in hemodynamics created by CERAB can lead to falsely high PSV requiring CT angiography (CTA) for further assessment. Therefore, the importance of DUS would be enhanced with a proposed PSV prediction tool to ascertain whether PSV falls within the acceptable range of prediction. We have developed a prediction tool based on idealized models of aortoiliac bifurcations with various infra-renal PSV (PSV ), iliac to aortic area ratios (R) and aortoiliac bifurcation angles (α). Taguchi method with orthogonal arrays (OA) was utilized to minimize the number of Computational Fluid Dynamics (CFD) simulations performed under physiologically realistic conditions. Analysis of Variance (ANOVA) and Multiple Linear Regression (MLR) analyses were performed to assess Goodness of fit and to predict PSV PSV and R were found to contribute 94.06% and 3.36% respectively to PSV . The Goodness of fit based on adjusted R improved from 99.1% to 99.9% based on linear and exponential functions. The PSV predictor based on the exponential model was evaluated with sixteen patient specific cases with a mean prediction error of 9.9% and standard deviation of 6.4%. Eleven out of sixteen cases (69%) in our current retrospective studies would have avoided CTA if the proposed predictor was used to screen out DUS measured PSV with prediction error greater than 15%. The predictor therefore has the potential to be used as a clinical tool to detect PSV more accurately post aortoiliac stenting and might reduce diagnostic errors and avoid unnecessary expense and risk from CTA follow-up imaging.
[Mh] Termos MeSH primário: Aorta Abdominal
Velocidade do Fluxo Sanguíneo/fisiologia
Artéria Ilíaca
Processamento de Imagem Assistida por Computador/métodos
Stents
[Mh] Termos MeSH secundário: Aorta Abdominal/diagnóstico por imagem
Aorta Abdominal/fisiologia
Aorta Abdominal/cirurgia
Implante de Prótese Vascular
Seres Humanos
Artéria Ilíaca/diagnóstico por imagem
Artéria Ilíaca/fisiologia
Artéria Ilíaca/cirurgia
Modelos Estatísticos
Sístole/fisiologia
Ultrassonografia Doppler
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180220
[Lr] Data última revisão:
180220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170502
[St] Status:MEDLINE


  10 / 19563 MEDLINE  
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[PMID]:29211221
[Au] Autor:Yang F; Qiu J; Fu Z; Qiu Y; Luo J; Xiao Q; Cao H
[Ad] Endereço:Institute of Animal Population Health, College of Animal Science and Technology, Jiangxi Agriculture University, Jiangxi, P.R. China.
[Ti] Título:Safety and Feasibility Study of a Novel Stent-Graft for Thoracic Endovascular Aortic Repair: a Canine Model Experiment.
[So] Source:Braz J Cardiovasc Surg;32(5):401-407, 2017 Sep-Oct.
[Is] ISSN:1678-9741
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To evaluate the safety and feasibility of a novel stent-graft for thoracic endovascular aortic repair (TEVAR) in a canine model, 9 adult hybrid dogs were used for the experiment. METHODS: All animals were implanted with a novel thoracic aortic stent-graft via femoral artery. Blood sample was collected at pre-operation and 1, 2, 4, 8 and 12 weeks after implantation for hematological examination. Moreover, tissues from randomly selected 4 dogs were subjected to histopathological analysis with the optical microscope after stent-grafts were implanted for 3, 6, 9, and 12 months respectively. The experimental period lasted for more than 2 years. RESULTS: A total of 9 stent-grafts were successfully implanted in the canine thoracic aortas and no migration or deformation occurred. Related indicators of blood routine, inflammatory factors, and immunology changes were not significantly (P>0.05), except the white blood cell (WBC) counts in the first week. Moreover, abnormal morphology was not found in all thoracic aortas via histopathological examination. Additionally, all stent-grafts were patent and did not migrate, and there was no thrombus in the lumens of stent-grafts. CONCLUSION: The novel thoracic aortic stent-graft made in China was safe and feasible for thoracic endovascular aortic repair in a canine model.
[Mh] Termos MeSH primário: Aorta Torácica/cirurgia
Implante de Prótese Vascular
Procedimentos Endovasculares/instrumentação
Stents
[Mh] Termos MeSH secundário: Animais
Cães
Estudos de Viabilidade
Teste de Materiais
Modelos Animais
Desenho de Prótese
Fatores de Tempo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180216
[Lr] Data última revisão:
180216
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171207
[St] Status:MEDLINE



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BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde