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Referências encontradas : 40 [refinar]
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Fotocópia
[PMID]:16325836
[Au] Autor:Schellin M; Popp P
[Ad] Endereço:Department of Analytical Chemistry, UFZ-Centre for Environmental Research, Permoserstrasse 15, 04318 Leipzig, Germany. manuela.schellin@ufz.de
[Ti] Título:Miniaturized membrane-assisted solvent extraction combined with gas chromatography/electron-capture detection applied to the analysis of volatile organic compounds.
[So] Source:J Chromatogr A;1103(2):211-8, 2006 Jan 27.
[Is] ISSN:0021-9673
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:A new module of membrane-assisted solvent extraction (MASE) with miniaturized membrane bags was applied to the determination of seven volatile organic compounds (VOCs): chloroform, 1,1,1-trichloroethane, trichloroethylene, 1,1,2-trichloroethane, tetrachloroethene, 1,1,1,2-tetrachloroethane, 1,1,2,2-tetrachloroethane with boiling points between 61 and 147 degrees C in aqueous samples. Different from the known procedure the new, shortened membrane bags were filled with 100 microl of an organic solvent. The membrane bags were placed in a 20 ml headspace vial and filled with 15 ml of the aqueous sample. The vial was transferred into an autosampler where it was stirred for a definite time at elevated temperature. After the extraction, 1 microl of the organic extract was transferred into the spilt/splitless injector of a GC system equipped with an electron-capture detector. This work included optimization of the membrane device, the determination of the optimized extraction conditions such as stirring rate, extraction time and the impact of salt addition. The validation of the method involved repeatability, recovery and detection limit studies, followed of its application towards real water samples. The repeatability, expressed as the relative standard deviation of the peak areas of six extractions was below 10%. The detection limits (LODs) were between 5 ng/l (tetrachloroethene) and 50 ng/l (chloroform). Calibration was performed in a range from 5 ng/l to 150 microg/l, since the concentration in the aqueous samples was expected quite various in this concentration range. Five river water samples of Bitterfeld, Saxony-Anhalt, Germany were analyzed with miniaturized-MASE and the results were compared with those obtained with Headspace-Analysis. The method can be fully automated and moreover, it allows the simultaneous determination of volatile and semi volatile compounds.
[Mh] Termos MeSH primário: Cromatografia Gasosa/métodos
Hidrocarbonetos Clorados/análise
Hipofisectomia Química/métodos
Poluentes Químicos da Água/análise
[Mh] Termos MeSH secundário: Elétrons
Cromatografia Gasosa-Espectrometria de Massas/métodos
Hipofisectomia Química/instrumentação
Membranas Artificiais
Volatilização
[Pt] Tipo de publicação:JOURNAL ARTICLE; VALIDATION STUDIES
[Nm] Nome de substância:
0 (Hydrocarbons, Chlorinated); 0 (Membranes, Artificial); 0 (Water Pollutants, Chemical)
[Em] Mês de entrada:0603
[Cu] Atualização por classe:090115
[Lr] Data última revisão:
090115
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:051206
[St] Status:MEDLINE


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Fotocópia
[PMID]:1721037
[Au] Autor:Morimoto M; Harano K; Hirakawa N; Totoki T
[Ad] Endereço:Department of Anesthesiology, Saga Medical School.
[Ti] Título:Diffusion of alcohol upon application of neuroadenolysis of the pituitary gland (NALP). An experimental study using HRP and WGA-HRP in the cat.
[So] Source:Fukuoka Igaku Zasshi;82(9):475-9, 1991 Sep.
[Is] ISSN:0016-254X
[Cp] País de publicação:Japan
[La] Idioma:eng
[Ab] Resumo:Diffusion of alcohol in neuroadenolysis of pituitary gland (NALP) was observed by injection of horseradish peroxidase (HRP) or wheat germ agglutinin-HRP conjugates (WGA-HRP) into the pituitary of the cat. After small-amount injection of WGA-HRP into the pituitary, WGA-HRP labeling was observed markedly around the third ventricle and the ventral part of the hypothalamus. While, in large-amount injection of WGA-HRP, it extended to all of the ventricular systems and dipped into the substances of the brain and spinal cord through the ependyma. These results suggest that the main site of action for alcohol injected into the pituitary is probably the hypothalamus.
[Mh] Termos MeSH primário: Ventrículos Cerebrais/metabolismo
Peroxidase do Rábano Silvestre/farmacocinética
Hipofisectomia Química
Hipotálamo/metabolismo
[Mh] Termos MeSH secundário: Animais
Gatos
Difusão
Feminino
Peroxidase do Rábano Silvestre/administração & dosagem
Injeções
Masculino
Conjugado Aglutinina do Germe de Trigo-Peroxidase do Rábano Silvestre
Aglutininas do Germe de Trigo/administração & dosagem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate); 0 (Wheat Germ Agglutinins); EC 1.11.1.- (Horseradish Peroxidase)
[Em] Mês de entrada:9201
[Cu] Atualização por classe:031114
[Lr] Data última revisão:
031114
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:910901
[St] Status:MEDLINE


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Fotocópia
[PMID]:1662226
[Au] Autor:Török A; Hamori M; Tinneberg HR; Cledon P; Gagsteiger F; Hanf V
[Ad] Endereço:Department of Obstetrics and Gynaecology, University of Tübingen, FRG.
[Ti] Título:Comparison of the effects of HMG or pure FSH stimulation during suppression with an LHRH agonist analogue.
[So] Source:Hum Reprod;6(7):922-4, 1991 Aug.
[Is] ISSN:0268-1161
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Infertile patients who responded poorly in an in-vitro fertilization programme were treated with human menopausal gonadotrophin (HMG) or with pure follicle stimulating hormone (FSH) during continuous administration of a luteinizing hormone-releasing hormone (LHRH) agonist, to determine whether a low level of LH is required for follicle maturation. No statistically significant differences were detected in the dose of gonadotrophins, duration of treatment, oestradiol and LH levels, numbers of recovered oocytes, transferred embryos or fertilization rates. It is concluded that an absence of low levels of LH does not disturb follicular development in the follicular phase. Based on the low fertilization rates in the present study (0.32 with HMG versus 0.45 with FSH) the authors suggest that, as well as hormonal deficiency, other factors may also influence follicular and early embryonic development.
[Mh] Termos MeSH primário: Hormônio Foliculoestimulante/uso terapêutico
Hormônio Luteinizante/uso terapêutico
Menotropinas/uso terapêutico
Hipófise/fisiologia
Receptores LHRH/efeitos dos fármacos
Superovulação/efeitos dos fármacos
[Mh] Termos MeSH secundário: Estradiol/sangue
Feminino
Seres Humanos
Hipofisectomia Química
Hormônio Luteinizante/sangue
Folículo Ovariano/efeitos dos fármacos
Folículo Ovariano/fisiologia
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Receptors, LHRH); 4TI98Z838E (Estradiol); 61489-71-2 (Menotropins); 9002-67-9 (Luteinizing Hormone); 9002-68-0 (Follicle Stimulating Hormone)
[Em] Mês de entrada:9202
[Cu] Atualização por classe:131121
[Lr] Data última revisão:
131121
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:910801
[St] Status:MEDLINE


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Fotocópia
[PMID]:2382160
[Au] Autor:Jackson JA; Trowbridge A; Smigiel M
[Ad] Endereço:Department of Medicine, Scott and White Clinic, Scott and White Memorial Hospital, Temple, TX 76508.
[Ti] Título:Fatal pulmonary thromboembolism after successful transsphenoidal hypophysectomy for Cushing's disease.
[So] Source:South Med J;83(8):960-2, 1990 Aug.
[Is] ISSN:0038-4348
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:We have reported the case of a 30-year-old woman with Cushing's disease who died of massive pulmonary thromboembolism 5 weeks after successful transsphenoidal hypophysectomy. Glucocorticoid excess appears to cause a hypercoagulable state, and consideration of this thromboembolic propensity and its potential duration after cure is indicated in all patients with Cushing's syndrome during the perioperative period. At the present time, we recommend the routine perioperative use of intermittent pneumatic compression in all patients with Cushing's disease or Cushing's syndrome.
[Mh] Termos MeSH primário: Síndrome de Cushing/cirurgia
Hipofisectomia Química/efeitos adversos
Hipofisectomia/efeitos adversos
Embolia Pulmonar/etiologia
[Mh] Termos MeSH secundário: 17-Hidroxicorticosteroides/urina
Adulto
Síndrome de Cushing/sangue
Síndrome de Cushing/urina
Feminino
Seres Humanos
Hidrocortisona/sangue
Hidrocortisona/urina
Hipofisectomia Química/métodos
Embolia Pulmonar/sangue
Embolia Pulmonar/urina
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (17-Hydroxycorticosteroids); WI4X0X7BPJ (Hydrocortisone)
[Em] Mês de entrada:9009
[Cu] Atualização por classe:131121
[Lr] Data última revisão:
131121
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:900801
[St] Status:MEDLINE


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Fotocópia
[PMID]:2666689
[Au] Autor:Iwasaki T; Hayashi N; Kimura I; Sutoh Y; Nakashima T; Odori T; Ishii Y; Tsubokawa T
[Ti] Título:[Percutaneous ethanol injection of parathyroid adenoma under US guidance].
[So] Source:Rinsho Hoshasen;34(2):261-4, 1989 Feb.
[Is] ISSN:0009-9252
[Cp] País de publicação:Japan
[La] Idioma:jpn
[Ab] Resumo:A patient with post-operative recurrent parathyroid adenoma was treated with percutaneous injection of absolute ethanol under ultrasonographic guidance. Serum calcium and PTH level were both successfully normalized, while recurrent nerve palsy was encountered as side effect. Six months later, she was suffered from hyperparathyroidism again, because of local tumor recurrence. Her recurrent nerve palsy was cured at that time. This technic could be a simple and non-invasive alternative for the conventional surgical procedure, but the indication for larger adenomas like this case should be carefully considered.
[Mh] Termos MeSH primário: Adenoma/terapia
Hipofisectomia Química
Hipofisectomia
Neoplasias das Paratireoides/terapia
[Mh] Termos MeSH secundário: Adulto
Feminino
Seres Humanos
Recidiva Local de Neoplasia/terapia
Ultrassonografia
[Pt] Tipo de publicação:CASE REPORTS; ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Mês de entrada:8908
[Cu] Atualização por classe:061115
[Lr] Data última revisão:
061115
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:890201
[St] Status:MEDLINE


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Fotocópia
[PMID]:2525653
[Au] Autor:Deckers GH; Schuurs AH
[Ad] Endereço:Biochemical Pharmacology Department, Organon, Scientific Development Group, Oss, The Netherlands.
[Ti] Título:Aromatase inhibition in hypophysectomised female rats: a novel animal model for in vivo screening.
[So] Source:J Steroid Biochem;32(5):625-31, 1989 May.
[Is] ISSN:0022-4731
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:An experimental model for in vivo screening of aromatase inhibitors was developed which overcomes the interference of compounds centrally active via the pituitary-gonad axis. Mature female surgically or chemically hypophysectomised (hypx) rats were treated with the oestrogen precursor dehydroepiandrosterone sulphate (DHEAS), immediately followed by administration of the test compound. During the treatment period vaginal smears were prepared daily. In the hypx rats DHEAS was metabolised to oestrogens, which induced vaginal cornification. By determining oestradiol levels it was shown that the aromatase inhibitors tested antagonised oestrogen synthesis and, as a result, cornification was counteracted. 4-Hydroxyandrostenedione and SH 489 showed equipotent aromatase inhibition, whereas 19-mercapto-androstenedione (ORG 30365) was at least twice as potent as the former compounds. By using various oestrogen precursors the inhibition of the enzyme aromatase was demonstrated. For in vivo screening of compounds on their aromatase inhibiting activity the assay in hypx rats appeared to be very suitable and selective but, because anti-oestrogens also antagonise vaginal cornification, anti-oestrogenic activity has to be excluded.
[Mh] Termos MeSH primário: Inibidores da Aromatase
Hipofisectomia
[Mh] Termos MeSH secundário: Animais
Desidroepiandrosterona/metabolismo
Estradiol/sangue
Estrogênios/biossíntese
Feminino
Hipofisectomia Química
Ovariectomia
Ratos
Vagina/efeitos dos fármacos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Aromatase Inhibitors); 0 (Estrogens); 459AG36T1B (Dehydroepiandrosterone); 4TI98Z838E (Estradiol)
[Em] Mês de entrada:8907
[Cu] Atualização por classe:131121
[Lr] Data última revisão:
131121
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:890501
[St] Status:MEDLINE


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Fotocópia
[PMID]:2498446
[Au] Autor:Remorgida V; Anserini P; Croce S; Costa M; Ferraiolo A; Centonze A; Gaggero G; Capitanio GL
[Ad] Endereço:Department of Obstetrics and Gynecology, University of Genoa, Italy.
[Ti] Título:The duration of pituitary suppression by means of intranasal gonadotropin hormone-releasing hormone analogue administration does not influence the ovarian response to gonadotropin stimulation and success rate in a gamete intrafallopian transfer (GIFT) program.
[So] Source:J In Vitro Fert Embryo Transf;6(2):76-80, 1989 Apr.
[Is] ISSN:0740-7769
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The aim of the study was to compare the ability to prevent endogenous luteinizing hormone interferences, ovarian response, and success rate between two groups of patients undergoing GIFT procedures and treated with the same stimulatory protocol but with a different timing in the administration of the gonadotropin hormone-releasing hormone analogue (GnRH-a). The former underwent a concomitant administration of gonadotropin and analogue; the latter started stimulation only after the achievement of complete hypogonadotropinism. The analogue was always given intranasally and stimulation was identical in the two groups. Our results showed that (1) prevention of premature luteinization is obtained with both approaches and (2) no significant difference in terms of length of stimulation, gonadotropin doses, ovarian response, and success rate was recorded between the two groups.
[Mh] Termos MeSH primário: Busserrelina/farmacologia
Transferência Intrafalopiana de Gameta
Gonadotropinas/farmacologia
Ovário/efeitos dos fármacos
Hipófise/efeitos dos fármacos
[Mh] Termos MeSH secundário: Administração Intranasal
Adulto
Esquema de Medicação
Feminino
Seres Humanos
Hipofisectomia Química
Masculino
Ciclo Menstrual
Meia-Idade
Fatores de Tempo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Gonadotropins); PXW8U3YXDV (Buserelin)
[Em] Mês de entrada:8906
[Cu] Atualização por classe:131121
[Lr] Data última revisão:
131121
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:890401
[St] Status:MEDLINE


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Fotocópia
[PMID]:3659046
[Au] Autor:Thiebault JB; Thurel C; Cunin G; Serie A
[Ad] Endereço:Service de neuro-chirurgie, Hôpital H. Dunant, Paris.
[Ti] Título:The role of neurosurgery in the non-specific treatment of prostatic cancer pain.
[So] Source:Prog Clin Biol Res;243B:493-6, 1987.
[Is] ISSN:0361-7742
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Hipofisectomia Química
Hipofisectomia
Morfina/administração & dosagem
Manejo da Dor
Neoplasias da Próstata/fisiopatologia
Medula Espinal/cirurgia
[Mh] Termos MeSH secundário: Seres Humanos
Injeções Intraventriculares
Masculino
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
76I7G6D29C (Morphine)
[Em] Mês de entrada:8711
[Cu] Atualização por classe:131121
[Lr] Data última revisão:
131121
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:870101
[St] Status:MEDLINE


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Fotocópia
[PMID]:3644858
[Au] Autor:Waldman SD; Feldstein GS; Allen ML
[Ti] Título:Neuroadenolysis of the pituitary: description of a modified technique.
[So] Source:J Pain Symptom Manage;2(1):45-9, 1987.
[Is] ISSN:0885-3924
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Etanol/administração & dosagem
Hipofisectomia Química/métodos
Hipofisectomia/métodos
Dor Intratável/terapia
[Mh] Termos MeSH secundário: Idoso
Neoplasias da Mama/fisiopatologia
Feminino
Seres Humanos
Masculino
Meia-Idade
Hipófise/fisiopatologia
Neoplasias da Próstata/fisiopatologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
3K9958V90M (Ethanol)
[Em] Mês de entrada:8705
[Cu] Atualização por classe:171114
[Lr] Data última revisão:
171114
[Sb] Subgrupo de revista:N
[Da] Data de entrada para processamento:870101
[St] Status:MEDLINE


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Fotocópia
[PMID]:3446826
[Au] Autor:Fujita T
[Ti] Título:[Present status of neuroadenolysis of the pituitary gland (NALP) for the relief of terminal cancer pain in Japan].
[So] Source:Masui;36(11):1696-705, 1987 Nov.
[Is] ISSN:0021-4892
[Cp] País de publicação:Japan
[La] Idioma:jpn
[Mh] Termos MeSH primário: Hipofisectomia Química/métodos
Hipofisectomia/métodos
Neoplasias/complicações
Dor Intratável/terapia
[Mh] Termos MeSH secundário: Feminino
Masculino
[Pt] Tipo de publicação:ENGLISH ABSTRACT; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:8805
[Cu] Atualização por classe:061115
[Lr] Data última revisão:
061115
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:871101
[St] Status:MEDLINE



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