Base de dados : MEDLINE
Pesquisa : E04.540.450 [Categoria DeCS]
Referências encontradas : 1069 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 107 ir para página                         

  1 / 1069 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28470642
[Au] Autor:Hammer A; Wolfensberger TJ
[Ad] Endereço:Jules Gonin Eye Hospital, University of Lausanne, Lausanne, Switzerland.
[Ti] Título:Iris Clip Lens Implantation with Novel Approach for Aphakia After Previous Filtration Surgery.
[Ti] Título:Irisfixierte Linsenimplantation nach Filtrationschirurgie..
[So] Source:Klin Monbl Augenheilkd;234(4):432-435, 2017 Apr.
[Is] ISSN:1439-3999
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:To present a novel and simplified surgical technique of Artisan lens implantation for intraocular lens luxation and aphakia in glaucoma patients with previous superior filtration surgery. Analysis of 12 patients with a history of previous superior filtration surgery for glaucoma, who underwent artisan lens implantation. To allow lens manipulation and implantation without alteration of the filtration bleb, the main sclerocorneal incision was performed laterally and the Artisan lens was held in place for enclavation of the iris stroma via a superior corneal incision without disturbing the filtration bleb. Mean pre-operative visual acuity was 0.54 ± 0.85 LogMAR, and intraocular pressure (IOP) was 15.8 ± 7.7 mmHg. At the end of follow-up (11.6 ± 8.1 months), visual acuity had improved to 0.32 ± 0.57 LogMAR and intraocular pressure was 14.7 ± 5.4 mmHg. No disturbance of the filtration bleb was observed. Artisan lens implantation can be performed successfully via a combined lateral and superior approach despite the presence of a filtration bleb at the 12 o'clock position.
[Mh] Termos MeSH primário: Afacia/terapia
Cirurgia Filtrante/instrumentação
Cirurgia Filtrante/métodos
Implante de Lente Intraocular/instrumentação
Implante de Lente Intraocular/métodos
Lentes Intraoculares
[Mh] Termos MeSH secundário: Idoso
Idoso de 80 Anos ou mais
Afacia/diagnóstico
Terapia Combinada/instrumentação
Terapia Combinada/métodos
Feminino
Seres Humanos
Iris/cirurgia
Masculino
Resultado do Tratamento
Acuidade Visual
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180228
[Lr] Data última revisão:
180228
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170505
[St] Status:MEDLINE
[do] DOI:10.1055/s-0043-104430


  2 / 1069 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28449300
[Au] Autor:Seuthe AM; Januschowski K; Mariacher S; Ebner M; Opitz N; Szurman P; Boden K
[Ad] Endereço:Knappschaft Eye Clinic Sulzbach, Knappschaft Hospital Saar, Sulzbach, Germany.
[Ti] Título:The effect of canaloplasty with suprachoroidal drainage combined with cataract surgery - 1-year results.
[So] Source:Acta Ophthalmol;96(1):e74-e78, 2018 Feb.
[Is] ISSN:1755-3768
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:PURPOSE: The purpose of this study was to investigate the safety and efficacy of phacocanaloplasty with suprachoroidal drainage (PCscD) and to compare its intraocular pressure (IOP)-lowering and drug-sparing effect to canaloplasty with suprachoroidal drainage (CscD). METHODS: The study retrospective interventional study included patients with open-angle glaucoma or secondary forms of glaucoma who underwent either CscD or PCscD between the year 2011 and 2014 in Knappschaft Eye Clinic Sulzbach. Primary end-points were IOP reduction and the number of IOP-lowering medication after 12 months. Secondary end-points were intraoperative and postoperative complications. RESULTS: A total of 328 eyes were included, 193 were treated with CscD and 135 underwent PCscD. Canaloplasty with scD achieved an IOP reduction of 37.0% (from 20.9 ± 3.6 mmHg to 13.2 ± 2.6 mmHg) after 1 year, whereas PCscD showed a significant higher reduction of 47.4% (from 23.2 ± 5.1 mmHg to 12.2 ± 1.7 mmHg). Reduction in IOP-lowering medication was higher after PCscD (from 3.6 ± 0.6 to 0.2 ± 0.5) than after CscD (from 3.5 ± 0.8 to 0.7 ± 1.0). Twelve months after surgery 55.5% in the CscD group and 80.2% in the PCscD group were free of IOP-lowering medication. In both groups, no severe or sight-threatening complications occurred. CONCLUSION: Combining cataract surgery and CscD achieves a higher IOP reduction, and patients postoperatively need less IOP-lowering medication than after CscD alone.
[Mh] Termos MeSH primário: Catarata/complicações
Cirurgia Filtrante/métodos
Glaucoma de Ângulo Aberto/cirurgia
Pressão Intraocular
Facoemulsificação/métodos
Acuidade Visual
[Mh] Termos MeSH secundário: Idoso
Corioide
Feminino
Seguimentos
Glaucoma de Ângulo Aberto/complicações
Glaucoma de Ângulo Aberto/fisiopatologia
Seres Humanos
Masculino
Estudos Retrospectivos
Fatores de Tempo
Tonometria Ocular
Resultado do Tratamento
[Pt] Tipo de publicação:CLINICAL STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180209
[Lr] Data última revisão:
180209
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170428
[St] Status:MEDLINE
[do] DOI:10.1111/aos.13393


  3 / 1069 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28448670
[Au] Autor:Futakuchi A; Inoue T; Fujimoto T; Kuroda U; Inoue-Mochita M; Takahashi E; Ohira S; Tanihara H
[Ad] Endereço:Department of Ophthalmology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
[Ti] Título:Molecular Mechanisms Underlying the Filtration Bleb-Maintaining Effects of Suberoylanilide Hydroxamic Acid (SAHA).
[So] Source:Invest Ophthalmol Vis Sci;58(4):2421-2429, 2017 04 01.
[Is] ISSN:1552-5783
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Purpose: Suberoylanilide hydroxamic acid (SAHA) has been shown to support the maintenance of experimental filtration blebs in animal models. This study was performed to investigate the molecular mechanisms underlying the bleb-maintaining effects of SAHA in modulating wound healing activities of conjunctival fibroblasts. Methods: Human conjunctival fibroblasts (HConFs) were pretreated with SAHA before treatment with TGF-ß2. Microarray-based screening was used to investigate the gene expression profiles. Gene ontology (GO) analysis was conducted to categorize the gene functions. The expression of TGF-ß-induced signaling molecules, α-smooth muscle actin, and extracellular matrix (ECM) proteins were evaluated by Western blot analyses. Multiplex immunoassay was performed to evaluate supernatant cytokine concentrations. Tube formation assay was used to evaluate angiogenesis using human umbilical vein endothelial cells. Results: GO analysis showed that SAHA, in the presence of TGF-ß2, induced changes in expression of genes involved in the TGF-ß receptor signaling pathway, cell proliferation, extracellular matrix organization, inflammatory responses, and angiogenesis. Subsequent in vitro experiments showed that SAHA partly inhibited the phosphorylation of Smad2, Smad3, and Akt. SAHA pretreatment potently suppressed TGF-ß2-driven cell proliferation, myofibroblast differentiation, contraction, ECM production, and angiogenic cytokine expression. The supernatant of HConFs treated with SAHA inhibited tube formation. Conclusions: SAHA has been shown to suppress angiogenesis and activation of conjunctival fibroblasts partly via inhibition of Smad and non-Smad TGF-ß signaling. This in vitro study provides new evidence for the molecular basis of the potential bleb-maintaining effects of SAHA, a novel candidate drug in modulating scar formation after glaucoma filtration surgery.
[Mh] Termos MeSH primário: Inibidores da Angiogênese/farmacologia
Túnica Conjuntiva/efeitos dos fármacos
Fibroblastos/efeitos dos fármacos
Inibidores de Histona Desacetilases/farmacocinética
Ácidos Hidroxâmicos/farmacologia
[Mh] Termos MeSH secundário: Vesícula/metabolismo
Movimento Celular/efeitos dos fármacos
Proliferação Celular/efeitos dos fármacos
Células Cultivadas
Colágeno Tipo I/metabolismo
Túnica Conjuntiva/citologia
Citocinas/metabolismo
Proteínas da Matriz Extracelular/metabolismo
Fibroblastos/metabolismo
Cirurgia Filtrante
Perfilação da Expressão Gênica
Seres Humanos
Receptores de Fatores de Crescimento Transformadores beta/metabolismo
Transdução de Sinais/efeitos dos fármacos
Proteínas Smad/metabolismo
Análise Serial de Tecidos
Fator de Crescimento Transformador beta2/farmacologia
Cicatrização/efeitos dos fármacos
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Angiogenesis Inhibitors); 0 (Collagen Type I); 0 (Cytokines); 0 (Extracellular Matrix Proteins); 0 (Histone Deacetylase Inhibitors); 0 (Hydroxamic Acids); 0 (Receptors, Transforming Growth Factor beta); 0 (Smad Proteins); 0 (Transforming Growth Factor beta2); 58IFB293JI (vorinostat)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:180118
[Lr] Data última revisão:
180118
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170428
[St] Status:MEDLINE
[do] DOI:10.1167/iovs.16-21403


  4 / 1069 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28860043
[Au] Autor:Neustein RF; Beck AD
[Ad] Endereço:Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia.
[Ti] Título:Circumferential Trabeculotomy Versus Conventional Angle Surgery: Comparing Long-term Surgical Success and Clinical Outcomes in Children With Primary Congenital Glaucoma.
[So] Source:Am J Ophthalmol;183:17-24, 2017 Nov.
[Is] ISSN:1879-1891
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PURPOSE: This study compares the long-term efficacy of circumferential trabeculotomy to that of conventional angle surgeries in primary congenital glaucoma (PCG), as judged by glaucoma and visual outcomes. DESIGN: Retrospective observational case series. METHODS: Setting: Emory Eye Center, Atlanta, Georgia. STUDY POPULATION: This was a single-institution retrospective study involving children with PCG who underwent circumferential trabeculotomy, standard trabeculotomy, or goniotomy with ≥2-year follow-up. MAIN OUTCOME MEASURES: Postoperative success (intraocular pressure [IOP] < 22 mm Hg ± glaucoma medications, without glaucoma progression/additional IOP-lowering surgery), Snellen-equivalent visual acuity (VA), and IOP at last follow-up. Kaplan-Meier method estimated the probability of glaucoma control vs time postoperatively, and values were compared between angle surgery cohorts using Wilcoxon signed rank tests, Mann-Whitney U tests, and Fisher exact tests. RESULTS: Included were 58 eyes (33 children) after circumferential trabeculotomy and 42 eyes (27 children) after standard trabeculotomy/goniotomy, with mean follow-up of 7.2 ± 4.0 and 8.2 ± 4.5 years, respectively. Postoperative success at last follow-up in the circumferential vs conventional cohorts was 81% (47 of 58 eyes) vs 31% (13 of 42 eyes) (P < .0001). At last follow-up, the circumferential cohort had better median VA than the conventional cohort (20/30 (interquartile range [IQR] 20/25 to 20/70) vs 20/70 (IQR 20/40 to 20/200), P = .009), required fewer glaucoma medications (0.55 ± 1.2 vs 1.61 ± 1.51, P < .0001), had lower IOP in first operated eye (15.2 ± 3.6 vs 18.2 ± 7.0, P = .048), and had comparable incidence of devastating complications (P = .065). CONCLUSIONS: In this retrospective study, circumferential trabeculotomy afforded better long-term success and visual outcomes than conventional angle surgery for children with PCG.
[Mh] Termos MeSH primário: Glaucoma/cirurgia
Pressão Intraocular
Trabeculectomia/métodos
Acuidade Visual
[Mh] Termos MeSH secundário: Feminino
Cirurgia Filtrante/métodos
Seguimentos
Glaucoma/congênito
Glaucoma/fisiopatologia
Gonioscopia
Seres Humanos
Lactente
Masculino
Estudos Retrospectivos
Fatores de Tempo
Resultado do Tratamento
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; OBSERVATIONAL STUDY
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171102
[Lr] Data última revisão:
171102
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170902
[St] Status:MEDLINE


  5 / 1069 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28816817
[Au] Autor:Davo-Cabrera JM; Lanzagorta-Aresti A; Alcocer Yuste P
[Ad] Endereço:Fisabio Oftalmologia Medica, Valencia, Spain.
[Ti] Título:A Novel Surgical Technique for Ahmed Valves in Refractory Glaucoma With Silicone Oil Endotamponade.
[So] Source:J Glaucoma;26(10):e232-e235, 2017 Oct.
[Is] ISSN:1536-481X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PURPOSE: The purpose of the study is to describe a novel technique to implant Ahmed valves in patients with refractory glaucoma because of silicone oil (SO) endotamponade PATIENTS:: Three patients with glaucoma without SO removal were used as an example for this technique. METHODS: Technique report. RESULTS AND CONCLUSIONS: We introduce a standard technique modification for Ahmed valves in patients with SO. This modification consists on locating the Ahmed valve more tangential to the limbus curvature instead of the usual perpendicular position and inserting the tube in the posterior chamber. The tube can be longer and run parallel to pupil. This technique allows use superotemporal quadrant (fewer complications), avoid corneal touch and decrease SO loss through the tube to subconjunctival space.
[Mh] Termos MeSH primário: Tamponamento Interno/efeitos adversos
Cirurgia Filtrante/métodos
Implantes para Drenagem de Glaucoma
Glaucoma/cirurgia
Pressão Intraocular/fisiologia
Óleos de Silicone/efeitos adversos
[Mh] Termos MeSH secundário: Feminino
Glaucoma/fisiopatologia
Seres Humanos
Masculino
Meia-Idade
[Pt] Tipo de publicação:JOURNAL ARTICLE; TECHNICAL REPORT
[Nm] Nome de substância:
0 (Silicone Oils)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171102
[Lr] Data última revisão:
171102
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170818
[St] Status:MEDLINE
[do] DOI:10.1097/IJG.0000000000000737


  6 / 1069 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28784554
[Au] Autor:Grover DS; Flynn WJ; Bashford KP; Lewis RA; Duh YJ; Nangia RS; Niksch B
[Ad] Endereço:Glaucoma Associates of Texas, Dallas, Texas. Electronic address: dgrover@glaucomaassociates.com.
[Ti] Título:Performance and Safety of a New Ab Interno Gelatin Stent in Refractory Glaucoma at 12 Months.
[So] Source:Am J Ophthalmol;183:25-36, 2017 Nov.
[Is] ISSN:1879-1891
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PURPOSE: To evaluate the intraocular pressure (IOP)-lowering performance and safety of an ab interno gelatin stent (XEN 45 Gel Stent, Allergan plc, Irvine, California, USA), a minimally invasive glaucoma surgery device, in refractory glaucoma. DESIGN: Single-arm, open-label, multicenter clinical study. METHODS: Following mitomycin C pretreatment, the stent was placed ab interno in patients who failed prior filtering/cilioablative procedure or had uncontrolled IOP on maximum-tolerated medical therapy, with medicated IOP ≥20 and ≤35 mm Hg and visual field mean deviation ≤-3 dB. Primary performance outcomes: patients (%) achieving ≥20% IOP reduction from baseline on the same or fewer medications and mean IOP change from baseline at month 12. Procedure-related complications and ocular adverse events (AEs) were assessed. RESULTS: Sixty-five patients were implanted (intent-to-treat/safety population). At 12 months, 75.4% (46/61; observed data) reported ≥20% IOP lowering from baseline on the same or fewer medications. Mean IOP change from baseline was -9.1 mm Hg (95% confidence interval [CI]: -10.7, -7.5) (n = 52; observed data) at 12 months, excluding patients with missing data (n = 4) and those requiring a glaucoma-related secondary surgical intervention (n = 9). Mean medication count decreased from 3.5 (baseline) to 1.7 (12 months). No intraoperative complications or unexpected postoperative AEs were reported. Most AEs were mild/moderate; common AEs included needling (without sight-threatening complications), nonpersistent loss of best-corrected visual acuity, and transient hypotony (requiring no surgical intervention). CONCLUSIONS: The gelatin stent reduced IOP and medication use without raising unexpected safety concerns, offering a minimally invasive surgical option for refractory glaucoma patients.
[Mh] Termos MeSH primário: Cirurgia Filtrante/métodos
Gelatina
Implantes para Drenagem de Glaucoma
Glaucoma de Ângulo Aberto/cirurgia
Stents
Campos Visuais/fisiologia
[Mh] Termos MeSH secundário: Idoso
Feminino
Seguimentos
Glaucoma de Ângulo Aberto/diagnóstico
Glaucoma de Ângulo Aberto/fisiopatologia
Gonioscopia
Seres Humanos
Pressão Intraocular
Masculino
Meia-Idade
Estudos Prospectivos
Desenho de Prótese
Fatores de Tempo
Malha Trabecular/patologia
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE; MULTICENTER STUDY; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
9000-70-8 (Gelatin)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171102
[Lr] Data última revisão:
171102
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170809
[St] Status:MEDLINE


  7 / 1069 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28692738
[Au] Autor:Chong RS; Lee YS; Chu SWL; Toh LZ; Wong TTL
[Ad] Endereço:Singapore National Eye Centre, Singapore 2Singapore Eye Research Institute, Singapore 3Duke NUS Graduate Medical School, Singapore.
[Ti] Título:Inhibition of Monocyte Chemoattractant Protein 1 Prevents Conjunctival Fibrosis in an Experimental Model of Glaucoma Filtration Surgery.
[So] Source:Invest Ophthalmol Vis Sci;58(9):3432-3439, 2017 Jul 01.
[Is] ISSN:1552-5783
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Purpose: To evaluate the effect of treatment with monocyte chemoattractant protein-1 receptor inhibitor (MCP-Ri) to maintain bleb survival and prevent fibrosis in an experimental model of glaucoma filtration surgery (GFS). Methods: GFS was performed on one eye of C57/Bl6 mice (n = 36) that was treated with MCP-Ri, mitomycin-C (MMC), or vehicle at the time of surgery. Real-time polymerase chain reaction was used to evaluate conjunctival expression of monocyte chemoattractant protein-1 (MCP-1), TGFB1, TGFB2, collagen 1a1 (Col1a1), sparc (Sparc), and fibronectin at 2 and 7 days following surgery. Anterior segment slit-lamp examination, optical coherence tomography, and confocal microscopy were performed in vivo at day 14. Eyes were processed for immunohistochemical staining of F4/80, a monocyte-macrophage marker, at day 2. In vitro experiments were also performed to compare the effect of MMC, MCP-Ri, and vehicle on the viability of mouse Tenon's fibroblasts. Results: Treatment with MCP-Ri results in a greater reduction in the percentage of F4/80-positive cells in conjunctival blebs and lesser MCP-1 gene expression following experimental GFS than MMC or control. Both MMC and MCP-Ri reduced Col1a1 and Sparc expression, but not fibronectin. TGFB1 decreased with MCP-Ri but not MMC; MMC but not MCP-Ri reduced TGFB2. MMC and MCP-Ri treatment resulted in the preservation of bleb height at day 14, as compared to control. MCP-Ri was less toxic to mouse Tenon's fibroblasts in comparison with MMC. Conclusions: Targeting MCP-1 results in prolonged bleb survival following experimental GFS with less cellular toxicity as compared to MMC. MCP inhibition could provide a safer alternative to conventional antifibrotic adjunctive treatments in GFS.
[Mh] Termos MeSH primário: Antifibrinolíticos/farmacologia
Quimiocina CCL2/antagonistas & inibidores
Túnica Conjuntiva/efeitos dos fármacos
Inibidores Enzimáticos/farmacologia
Fibroblastos/efeitos dos fármacos
Fibrose/prevenção & controle
Implantes para Drenagem de Glaucoma
Glaucoma/tratamento farmacológico
Receptores CCR2/antagonistas & inibidores
[Mh] Termos MeSH secundário: Animais
Sobrevivência Celular/efeitos dos fármacos
Quimiocina CCL2/metabolismo
Colágeno/metabolismo
Modelos Animais de Doenças
Fibronectinas/metabolismo
Cirurgia Filtrante
Glaucoma/cirurgia
Camundongos
Camundongos Endogâmicos C57BL
Mitomicina/farmacocinética
Osteonectina/metabolismo
Fator de Crescimento Transformador beta/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antifibrinolytic Agents); 0 (Chemokine CCL2); 0 (Enzyme Inhibitors); 0 (Fibronectins); 0 (Osteonectin); 0 (Receptors, CCR2); 0 (SPARC protein, mouse); 0 (Transforming Growth Factor beta); 50SG953SK6 (Mitomycin); 9007-34-5 (Collagen)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170714
[Lr] Data última revisão:
170714
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170711
[St] Status:MEDLINE
[do] DOI:10.1167/iovs.17-21480


  8 / 1069 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28692597
[Au] Autor:Vinod K; Gedde SJ; Feuer WJ; Panarelli JF; Chang TC; Chen PP; Parrish RK
[Ad] Endereço:*Department of Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, Icahn School of Medicine, New York, NY †Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, Miami, FL ‡Department of Ophthalmology, University of Washington, Seattle, WA.
[Ti] Título:Practice Preferences for Glaucoma Surgery: A Survey of the American Glaucoma Society.
[So] Source:J Glaucoma;26(8):687-693, 2017 Aug.
[Is] ISSN:1536-481X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PURPOSE: The purpose of this study is to assess surgical practice patterns among the American Glaucoma Society (AGS) membership. METHODS: An anonymous online survey evaluating the use of glaucoma surgeries in various clinical settings was redistributed to AGS members. Survey responses were compared with prior results from 1996, 2002, and 2008 to determine shifts in surgical practice patterns. Questions were added to assess the preferred approach to primary incisional glaucoma surgery and phacoemulsification combined with glaucoma surgery. RESULTS: A total of 252 of 1091 (23%) subscribers to the AGS-net participated in the survey. Percentage use (mean±SD) of trabeculectomy with mitomycin C (MMC), glaucoma drainage device (GDD), and minimally invasive glaucoma surgery (MIGS) as an initial surgery in patients with primary open angle glaucoma was 59%±30%, 23%±23%, and 14%±20%, respectively. Phacoemulsification cataract extraction alone was the preferred surgical approach in 44%±32% of patients with primary open angle glaucoma and visually significant cataract, and phacoemulsification cataract extraction was combined with trabeculectomy with MMC in 24%±23%, with MIGS in 22%±27%, and with GDD in 9%±14%. Although trabeculectomy was selected most frequently to surgically manage glaucoma in 8 of 8 clinical settings in 1996, GDD was preferred in 7 of 8 clinical settings in 2016. CONCLUSIONS: The use of GDD has increased and that of trabeculectomy has concurrently decreased over the past 2 decades. Trabeculectomy with MMC is the most popular primary incisional surgery when performed alone or in combination with phacoemulsification cataract extraction. Surgeons frequently manage coexistent cataract and glaucoma with cataract extraction alone, rather than as a combined cataract and glaucoma procedure.
[Mh] Termos MeSH primário: Cirurgia Filtrante/métodos
Glaucoma de Ângulo Aberto/cirurgia
Padrões de Prática Médica/estatística & dados numéricos
[Mh] Termos MeSH secundário: Alquilantes/administração & dosagem
Catarata/complicações
Feminino
Fluoruracila/administração & dosagem
Implantes para Drenagem de Glaucoma
Glaucoma de Ângulo Aberto/complicações
Glaucoma de Ângulo Aberto/fisiopatologia
Seres Humanos
Pressão Intraocular/fisiologia
Masculino
Mitomicina/administração & dosagem
Oftalmologia/organização & administração
Facoemulsificação
Sociedades Médicas/estatística & dados numéricos
Inquéritos e Questionários
Trabeculectomia/métodos
Estados Unidos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Alkylating Agents); 50SG953SK6 (Mitomycin); U3P01618RT (Fluorouracil)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170711
[St] Status:MEDLINE
[do] DOI:10.1097/IJG.0000000000000720


  9 / 1069 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28598961
[Au] Autor:Grover DS; Fellman RL
[Ad] Endereço:Glaucoma Associates of Texas, Dallas, TX.
[Ti] Título:Adjustable Dual Muscle Speculum for Simplified Placement of a 350 Baerveldt Implant.
[So] Source:J Glaucoma;26(7):673-674, 2017 Jul.
[Is] ISSN:1536-481X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The authors have designed a muscle hook speculum that simultaneously allows the surgeon to isolate and expose both rectus muscles (either the superior and temporal or medial and inferior) for ease of placement of a 350-mm Baerveldt implant. This instrument facilitates the exposure and subsequent placement of either a superior-temporal tube or an infero-nasal tube in a more independent manner. By using the dual muscle hook speculum, an individual surgeon, without a glaucoma-trained assistant, can hook typically both the superior and lateral recti muscles while gaining simultaneous exposure of the quadrant. The purpose of this report is to describe the instrument, how it is used, and how it can improve efficiency in the operating room.
[Mh] Termos MeSH primário: Cirurgia Filtrante/instrumentação
Implantes para Drenagem de Glaucoma
Músculos Oculomotores/cirurgia
Implante de Prótese/métodos
[Mh] Termos MeSH secundário: Glaucoma/cirurgia
Seres Humanos
Pressão Intraocular
Instrumentos Cirúrgicos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171024
[Lr] Data última revisão:
171024
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170610
[St] Status:MEDLINE
[do] DOI:10.1097/IJG.0000000000000692


  10 / 1069 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28586797
[Au] Autor:Mastropasqua R; Fasanella V; Brescia L; Oddone F; Mariotti C; Di Staso S; Agnifili L
[Ad] Endereço:Moorfields Eye Hospital, London, United Kingdom.
[Ti] Título:In Vivo Confocal Imaging of the Conjunctiva as a Predictive Tool for the Glaucoma Filtration Surgery Outcome.
[So] Source:Invest Ophthalmol Vis Sci;58(6):BIO114-BIO120, 2017 May 01.
[Is] ISSN:1552-5783
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Purpose: To examine the preoperative conjunctival dendritic cell density (DCD), goblet cell density (GCD), and stromal meshwork reflectivity (SMR) in glaucomatous patients undergoing filtration surgery, using in vivo confocal microscopy (IVCM). Methods: Sixty-six patients were enrolled. At baseline, IVCM was performed at the site planned for surgery, and was repeated after 12 months at bleb site. Surgery was successful when a one-third reduction of baseline IOP was obtained at the last follow-up. The main outcomes were baseline DCD, GCD, and SMR, and 12 months IOP. The relations between baseline confocal parameters and 12 months IOP were analyzed. Results: Filtration surgery was successful in 43 patients (group 1: complete success, 25; group 2: qualified success, 18), and unsuccessful in 23 patients (group 3). Baseline IOP (mm Hg) was 27.6 ± 2.8, 28.8 ± 4.1, and 27.7 ± 3.2 in groups 1 to 3, respectively. Preoperative DCD and SMR were lower in group 1 compared with groups 2 (P < 0.001, P < 0.05), and 3 (P < 0.001); preoperative GCD was higher in group 1 compared with groups 2 and 3 (P < 0.001). DCD and GCD were also different between groups 2 and 3 (P < 0.05, P < 0.001). At 12 months, IOP reduced by 43.3%, 38.4%, and 15.8% in groups 1 to 3. Twelve-month IOP reduction negatively correlated with baseline DCD and SMR (P < 0.001, r = -0.786; P < 0.05, r = -0.618), and positively with GCD (P < 0.001, r = 0.752). Conclusions: Preoperative DCD, GCD, and SMR are parameters correlated with the filtration surgery outcome, with DCD presenting the strongest correlation. IVCM of the conjunctiva may represent an imaging tool to predict the surgical success in glaucoma.
[Mh] Termos MeSH primário: Túnica Conjuntiva/patologia
Cirurgia Filtrante/métodos
Implantes para Drenagem de Glaucoma
Glaucoma/cirurgia
Microscopia Confocal
[Mh] Termos MeSH secundário: Idoso
Estudos de Casos e Controles
Contagem de Células
Túnica Conjuntiva/citologia
Túnica Conjuntiva/diagnóstico por imagem
Técnicas Citológicas
Dendritos/patologia
Feminino
Glaucoma/patologia
Células Caliciformes/patologia
Seres Humanos
Pressão Intraocular
Masculino
Meia-Idade
Valor Preditivo dos Testes
Estudos Prospectivos
Trabeculectomia/métodos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170718
[Lr] Data última revisão:
170718
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170607
[St] Status:MEDLINE
[do] DOI:10.1167/iovs.17-21795



página 1 de 107 ir para página                         
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde