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[PMID]:28468202
[Au] Autor:Findik Y; Baykul T; Aydin MA; Altuntas S; Demirekin ZB
[Ad] Endereço:*Department of Oral and Maxillofacial Surgery †Department of Plastic and Reconstructive Surgery ‡Department of Prosthodontics, Faculty of Dentistry, Süleyman Demirel University, Isparta, Turkey.
[Ti] Título:Rehabilitation of the Work Accident-Related Traumatic Mandible With Iliac Free Flap, Distraction Osteogenesis, and Dental Implants.
[So] Source:J Craniofac Surg;28(3):e238-e239, 2017 May.
[Is] ISSN:1536-3732
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Mandibular bone defects due to extensive trauma impair occlusion and affect the aesthetics of facial contouring, making it difficult to obtain a satisfactory outcome. Distraction osteogenesis and free flap is an effective and aesthetic treatment option for rehabilating these defects. In this clinical report, the authors present rehabilitation of a wide mandibular traumatic defect due to a work-related accident with iliac free flap, distraction osteogenesis, and dental implants.
[Mh] Termos MeSH primário: Acidentes de Trabalho
Implantes Dentários
Retalhos de Tecido Biológico
Traumatismos Mandibulares/reabilitação
Traumatismos Mandibulares/cirurgia
Osteogênese por Distração
[Mh] Termos MeSH secundário: Adulto
Transplante Ósseo
Implantação Dentária Endo-Óssea
Seres Humanos
Masculino
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Dental Implants)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180205
[Lr] Data última revisão:
180205
[Sb] Subgrupo de revista:D
[Da] Data de entrada para processamento:170505
[St] Status:MEDLINE
[do] DOI:10.1097/SCS.0000000000003466


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[PMID]:28468145
[Au] Autor:McMillan K; Lloyd M; Evans M; White N; Nishikawa H; Rodrigues D; Sharp M; Noons P; Solanki G; Dover S
[Ad] Endereço:Birmingham Children's Hospital, Birmingham, UK.
[Ti] Título:Experiences in Performing Posterior Calvarial Distraction.
[So] Source:J Craniofac Surg;28(3):664-669, 2017 May.
[Is] ISSN:1536-3732
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The use of posterior calvarial distraction (PCD) for the management of craniosynostosis is well recognized. The advantages of using this technique include increased cranial volume, decreased intracranial pressure, relief of posterior fossa crowding, improved cerebrospinal fluid (CSF) circulation at the cranio-cervical junction with cessation, and possible resolution of syrinx.The authors retrospectively review their first 50 patients who have undergone PCD under the senior author's care in our unit.The demographics, diagnoses, intraoperative approach with techniques in distractor placement and outcomes of each patient were obtained through an electronic craniofacial database and written patient records. Analysis of complication rates (bleeding, distraction problems, CSF leaks, and infection) was included.A total of 31 boys and 19 girls underwent the procedure between October 2006 and September 2015 with a median age was 17.7 months (range 4 months to 19 years). Of those 50 children, 34 of the cohort were proven to be syndromic by genetic testing.The median length of inpatient stay was 9.4 days (range 3-43 days). Average distraction distance was 24 mm.Complications including CSF leaks, bleeding, distractor problems, and severe complications (recorded in 3 patients) are discussed. Our overall complication rate was 50%.Favorable outcomes included resolution of Chiari, syrinx, and raised intracranial pressure in the majority of patients where distraction was successful.The authors recommend that PCD should be considered the primary treatment for increasing calvarial volume. The authors discuss our experiences and technical innovations over the past decade.
[Mh] Termos MeSH primário: Fossa Craniana Posterior/cirurgia
Craniossinostoses/cirurgia
Osteogênese por Distração/métodos
Crânio/cirurgia
[Mh] Termos MeSH secundário: Adolescente
Vazamento de Líquido Cefalorraquidiano/etiologia
Rinorreia de Líquido Cefalorraquidiano/etiologia
Criança
Pré-Escolar
Feminino
Seguimentos
Seres Humanos
Lactente
Hipertensão Intracraniana/etiologia
Masculino
Estudos Retrospectivos
Síndrome
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180126
[Lr] Data última revisão:
180126
[Sb] Subgrupo de revista:D
[Da] Data de entrada para processamento:170505
[St] Status:MEDLINE
[do] DOI:10.1097/SCS.0000000000003458


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[PMID]:29228043
[Au] Autor:Meyers N; Schülke J; Ignatius A; Claes L
[Ad] Endereço:Institute of Orthopedic Research and Biomechanics, Center of Musculoskeletal Research Ulm, University Hospital Ulm, Ulm, Baden-Württemberg, Germany.
[Ti] Título:Novel systems for the application of isolated tensile, compressive, and shearing stimulation of distraction callus tissue.
[So] Source:PLoS One;12(12):e0189432, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Distraction osteogenesis is a procedure widely used for the correction of large bone defects. However, a high complication rate persists, likely due to insufficient stability during maturation. Numerical fracture healing models predict bone regeneration under different mechanical conditions allowing fixation stiffness optimization. However, most models apply a linear elastic material law inappropriate for the transient stresses/strains present during limb lengthening or segment transport. They are also often validated using in vivo osteotomy models lacking precise mechanical regulation due to the unavoidable stimulation of secondary interfragmentary motion during ambulation under finitely stiff fixation. Therefore, in order to create a robust numerical model of distraction osteogenesis, it is necessary to both characterize the new tissue's viscoelasticity during distraction and determine the influence of strictly isolated stimulation in each loading mode (tension, compression, and shear) to account for potential differences in mechanical and histological response. AIM: Two electromechanical fixators with integrated load cells were designed to precisely perform and monitor in vivo lateral distraction and isolated stimulation in sheep tibiae using a mobile, hydroxyapatite-coated titanium plate. The novel surgical procedure circumvents osteotomy, eliminating the undesirable and unquantifiable mechanical stimulation during ambulation. METHODS: After a 10-day post-surgery latency period, two 0.275 mm distraction steps were performed daily for 10 days. The load cell collected data before, during, and after each distraction step and was terminated after no less than one minute from the time of distraction. A 7-day consolidation period separated the distraction phase and 18-day stimulation phase. Stimulation was carried out in isolated tension, compression, or shear while recording force/time data. Each stimulation session consisted of 120 cycles with a magnitude of either 0.1 mm or 0.6 mm in the tension and compression groups and 1.0 mm in the shear group. The animals were euthanized after a 3-day holding period following stimulation. RESULTS: Our initial results show that the tissue progressively stiffens and maintains an increasingly large residual traction. The force curves during compressive stimulation show a progressive drift from compression toward tension. We hypothesize that this behavior may be due to the preferential flow of fluid outward from the tissue and a greater resistance to reabsorption during the plate's return to the starting position.
[Mh] Termos MeSH primário: Osteogênese por Distração
Estresse Mecânico
[Mh] Termos MeSH secundário: Animais
Ovinos
Software
[Pt] Tipo de publicação:JOURNAL ARTICLE; VALIDATION STUDIES
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180104
[Lr] Data última revisão:
180104
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171212
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0189432


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[PMID]:29182122
[Au] Autor:Castelein S; Docquier PL
[Ti] Título:Complications associated with bone lengthening of the lower limb by callotasis.
[So] Source:Acta Orthop Belg;82(4):806-813, 2016 Dec.
[Is] ISSN:0001-6462
[Cp] País de publicação:Belgium
[La] Idioma:eng
[Ab] Resumo:The present study aims to assess the incidence of complications related to bone lengthening procedures and to identify factors that may predict these complications. We retrospectively studied 51 lengthening procedures in 39 patients (mean age 13 years) from 2001 to 2015. A circular external fixator was used in 37 procedures and a monolateral fixator in 14 procedures. Duration of distraction, fixator's time, days of treatment, lengthening percentage, bone healing index, distraction regenerate length, distraction index, risk factors and complications were evaluated. The mean follow-up was 5 years. Complications occurred in 84 % of the procedures. Duration of distraction, fixator's time, days of treatment and distraction regenerate length were predictors of complications. Close follow-up is necessary during distraction and healing period and after fixator removal.
[Mh] Termos MeSH primário: Desigualdade de Membros Inferiores/cirurgia
Osteogênese por Distração/métodos
Complicações Pós-Operatórias/epidemiologia
Infecções Relacionadas à Prótese/epidemiologia
Infecção da Ferida Cirúrgica/epidemiologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Pinos Ortopédicos
Criança
Pré-Escolar
Depressão/epidemiologia
Fixadores Externos
Feminino
Seguimentos
Seres Humanos
Incidência
Lactente
Masculino
Pneumonia/epidemiologia
Estudos Retrospectivos
Fatores de Risco
Estresse Psicológico/epidemiologia
Fatores de Tempo
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171228
[Lr] Data última revisão:
171228
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171129
[St] Status:MEDLINE


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[PMID]:29212690
[Au] Autor:Ahmad A; Subramanian T; Panteliadis P; Wilson-Macdonald J; Rothenfluh DA; Nnadi C
[Ad] Endereço:Oxford University Hospitals NHS Trust, Windmill Road, Headington, Oxford, UK.
[Ti] Título:Quantifying the 'law of diminishing returns' in magnetically controlled growing rods.
[So] Source:Bone Joint J;99-B(12):1658-1664, 2017 Dec.
[Is] ISSN:2049-4408
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:AIMS: Magnetically controlled growing rods (MCGRs) allow non-invasive correction of the spinal deformity in the treatment of early-onset scoliosis. Conventional growing rod systems (CGRS) need repeated surgical distractions: these are associated with the effect of the 'law of diminishing returns'. The primary aim of this study was to quantify this effect in MCGRs over sequential distractions. PATIENTS AND METHODS: A total of 35 patients with a maximum follow-up of 57 months were included in the study. There were 17 boys and 18 girls with a mean age of 7.4 years (2 to 14). True Distraction (TD) was determined by measuring the expansion gap on fluoroscopy. This was compared with Intended Distraction (ID) and expressed as the 'T/I' ratio. The T/I ratio and the Cobb angle were calculated at several time points during follow-up. RESULTS: The mean follow-up was 30 months (6 to 57). There was a significant decrease in the mean T/I ratio over time (convex rod at 3 months 0.81, sd 0.58 51 months 0.17, sd 0.16, p = 0.0001; concave rod at 3 months 0.93, sd 0.67 51 months 0.18, sd 0.15, p = 0.0001). A linear decline of the mean T/I ratios was noted for both convex rods (r = 0.90, p = 0.004) and concave rods (r = 0.81, p = 0.015) over 51 months. At the 24-month follow-up stage, there was a significant negative correlation between the mean T/I ratio of the concave rod with weight (r = -0.59, p = 0.01), age (r = -0.59, p = 0.01), and BMI of the child (r = -0.54, p = 0.01). CONCLUSIONS: The 'law of diminishing returns' is also seen after serial distraction using MCGR. Compared to previously published data for CGRS, there is a gradual linear decline rather than a rapid initial decline in lengthening. In older, heavier children a reduced distraction ratio in the concave rod of the MCGR device is noted over time. Cite this article: 2017;99-B:1658-64.
[Mh] Termos MeSH primário: Procedimentos Cirúrgicos Minimamente Invasivos/instrumentação
Osteogênese por Distração/instrumentação
Reoperação/métodos
Escoliose/cirurgia
Fusão Vertebral/instrumentação
Coluna Vertebral/crescimento & desenvolvimento
[Mh] Termos MeSH secundário: Adolescente
Pinos Ortopédicos
Criança
Pré-Escolar
Feminino
Seguimentos
Seres Humanos
Imãs
Masculino
Osteogênese por Distração/métodos
Estudos Prospectivos
Escoliose/diagnóstico por imagem
Escoliose/fisiopatologia
Fusão Vertebral/métodos
Coluna Vertebral/diagnóstico por imagem
Coluna Vertebral/cirurgia
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE; OBSERVATIONAL STUDY
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171213
[Lr] Data última revisão:
171213
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171208
[St] Status:MEDLINE
[do] DOI:10.1302/0301-620X.99B12.BJJ-2017-0402.R2


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[PMID]:28962738
[Au] Autor:Suttorp CM; Desmedt DJS; Maal TJJ; Breuning KH
[Ad] Endereço:Department of Orthodontics and Craniofacial Biology, Radboud University Medical Centre, Nijmegen, The Netherlands.
[Ti] Título:Facial improvement after mandibular midline distraction and surgically assisted rapid maxillary expansion.
[So] Source:Am J Orthod Dentofacial Orthop;152(4):523-542, 2017 Oct.
[Is] ISSN:1097-6752
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:This case report describes the retreatment of a 49-year-old woman with severe crowding in the mandibular incisor region and tapered maxillary and mandibular arches. Treatment consisted of mandibular midline distraction and surgically assisted rapid maxillary expansion to increase arch length. The need for proper presurgical orthodontics is described, and the complications during treatment are discussed. The results of treatment, including the superimposition of 3-dimensional facial scans, are presented. The treatment approach we used is typically indicated for patients with previous extractions of all first premolars who develop significant crowding after treatment. Surgical planning in 3 dimensions and the use of a 3-dimensional designed surgical osteotomy guiding wafer should improve the predictability of this treatment approach.
[Mh] Termos MeSH primário: Estética Dentária
Face
Má Oclusão/cirurgia
Mandíbula/cirurgia
Osteogênese por Distração/métodos
Técnica de Expansão Palatina
[Mh] Termos MeSH secundário: Feminino
Seres Humanos
Meia-Idade
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171019
[Lr] Data última revisão:
171019
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:171001
[St] Status:MEDLINE


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[PMID]:28760282
[Au] Autor:Kurt G; Iseri H; Kisnisçi R; Özkaynak Ö
[Ad] Endereço:Department of Orthodontics, Faculty of Dentistry, Yeni Yuzyil University, Istanbul, Turkey. Electronic address: gokmenkurt@hotmail.com.
[Ti] Título:Rate of tooth movement and dentoskeletal effects of rapid canine retraction by dentoalveolar distraction osteogenesis: A prospective study.
[So] Source:Am J Orthod Dentofacial Orthop;152(2):204-213, 2017 Aug.
[Is] ISSN:1097-6752
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: The purpose of this study was to test the null hypothesis that duration of orthodontic treatment can be significantly reduced by accelerating canine retraction using dentoalveolar distraction (DAD). METHODS: Thirty-six maxillary canines of 19 patients comprised the DAD group, and 28 canines of 14 patients were included in the distalization group (DG). The initial mean ages were 15.8 ± 1.96 years for the DAD group and 16.02 ± 2.8 years for the DG. A custom-made, rigid, tooth-borne intraoral distraction device was used for the DAD group, and intraoral elastics were applied for canine distalization in the DG. Six skeletal and 11 dental variables were measured for the cephalometric evaluation. RESULTS: Canine retraction was 7.9 ± 1.49 mm in 11.8 ± 1.3 days and canine distal tipping was 11.48° ± 4.37° after DAD; the canines were distalized 5.29 ± 2.01 mm and tipped 13.64° ± 9.54° in 200 ± 57 days in the DG. The rates of posterior canine movement were 0.67 ± 0.14 mm per day after DAD and 0.03 ± 0.01 mm per day in the DG. No significant first molar anchorage loss was observed after DAD, although the DG showed some vertical and sagittal first molar movement. CONCLUSIONS: We failed to reject the null hypothesis. DAD can reduce the duration of orthodontic treatment time by accelerating canine retraction in extraction patients without undesirable side effects.
[Mh] Termos MeSH primário: Dente Canino
Má Oclusão/terapia
Osteogênese por Distração
Técnicas de Movimentação Dentária
[Mh] Termos MeSH secundário: Adolescente
Cefalometria
Feminino
Seres Humanos
Masculino
Procedimentos de Ancoragem Ortodôntica/instrumentação
Procedimentos de Ancoragem Ortodôntica/métodos
Braquetes Ortodônticos
Osteogênese por Distração/métodos
Estudos Prospectivos
Radiografia Panorâmica
Fatores de Tempo
Migração de Dente
Técnicas de Movimentação Dentária/instrumentação
Técnicas de Movimentação Dentária/métodos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170821
[Lr] Data última revisão:
170821
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:170802
[St] Status:MEDLINE


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[PMID]:28760270
[Au] Autor:Verma S; Singh S; Singh SP
[Ad] Endereço:Chandigarh, India.
[Ti] Título:Transport distraction osteogenesis combined with orthodontic treatment.
[So] Source:Am J Orthod Dentofacial Orthop;152(2):144, 2017 08.
[Is] ISSN:1097-6752
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Maxila
Osteogênese por Distração
[Mh] Termos MeSH secundário: Seres Humanos
Mandíbula
Procedimentos de Ancoragem Ortodôntica
[Pt] Tipo de publicação:LETTER; COMMENT
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170810
[Lr] Data última revisão:
170810
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:170802
[St] Status:MEDLINE


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[PMID]:28738191
[Au] Autor:Zhao K; Wang F; Huang W; Wang X; Wu Y
[Ad] Endereço:Graduate Student, Department of Oral Implantology and Department of Oral Craniomaxillofacial Surgery, Ninth People's Hospital Affiliated with Shanghai Jiao Tong University, School of Medicine, Shanghai, China.
[Ti] Título:Comparison of Dental Implant Performance Following Vertical Alveolar Bone Augmentation With Alveolar Distraction Osteogenesis or Autogenous Onlay Bone Grafts: A Retrospective Cohort Study.
[So] Source:J Oral Maxillofac Surg;75(10):2099-2114, 2017 Oct.
[Is] ISSN:1531-5053
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PURPOSE: The aim of this retrospective study was to compare the performance of implants placed after alveolar distraction osteogenesis (ADO) or autogenous onlay bone grafting (AOBG) based on implant survival, peri-implant bone resorption, and clinical parameters. MATERIALS AND METHODS: From February 2008 to July 2012, 17 patients (6 women and 11 men) with implant placement after ADO (group 1, n = 8) or AOBG (group 2, n = 9) were included in this retrospective study. In all, 37 implants were placed in group 1 and 22 implants were placed in group 2. Implant survival rate, peri-implant bone resorption, probe depth (PD), modified plaque index (mPI), and modified sulcus bleeding index (mSBI) were analyzed to evaluate implant prognosis. RESULTS: Successful reconstruction of vertical alveolar defects and uneventful implant placement were achieved in all patients in the 2 groups. After a mean follow-up of 47.9 ± 13.3 months, implant survival was 97.3% (36 of 37) in group 1 and 95.5% (21 of 22) in group 2. No statistically relevant differences were observed. Peri-implant bone resorption was 1.29 ± 0.59 mm in group 1, which was slightly higher than 1.24 ± 0.87 mm in group 2 at last follow-up. The difference was not statistically relevant. Favorable peri-implant conditions were indicated by PD, mPI, and mSBI in the 2 groups. CONCLUSIONS: ADO and AOBG can be used for correction of vertical alveolar defects with a reliable implant prognosis. Comparably high implant survival rates and favorable peri-implant conditions were attained.
[Mh] Termos MeSH primário: Aumento do Rebordo Alveolar/métodos
Transplante Ósseo
Implantação Dentária Endo-Óssea/métodos
Implantes Dentários
Osteogênese por Distração
[Mh] Termos MeSH secundário: Adolescente
Adulto
Estudos de Coortes
Feminino
Seres Humanos
Masculino
Meia-Idade
Falha de Prótese
Estudos Retrospectivos
Adulto Jovem
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Dental Implants)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171012
[Lr] Data última revisão:
171012
[Sb] Subgrupo de revista:AIM; D; IM
[Da] Data de entrada para processamento:170725
[St] Status:MEDLINE


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[PMID]:28688869
[Au] Autor:Wu CC; Sakahara D; Imai K
[Ad] Endereço:Craniofacial Center, Division of Plastic and Reconstructive Surgery, Department of Surgery, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, Taiwan.
[Ti] Título:Ankylosis of temporomandibular joints after mandibular distraction osteogenesis in patients with Nager syndrome: Report of two cases and literature review.
[So] Source:J Plast Reconstr Aesthet Surg;70(10):1449-1456, 2017 Oct.
[Is] ISSN:1878-0539
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Nager syndrome, also known as Nager acrofacial dysostosis, was first described by Nager and de Reynier in 1948. The patients commonly present with micrognathia, and a preventive tracheostomy is necessary when there are symptoms of upper airway obstruction. Mandibular distraction osteogenesis is considered as an effective procedure, which not only improves micrognathia but also minimizes the chances of tracheostomy. However, mandibular distraction osteogenesis has some complications such as relapse, teeth injury, infection, and injury of the temporomandibular joints (TMJs). In this study, the author reported two patients with Nager syndrome who suffered from ankylosis of TMJs after mandibular distraction osteogenesis. In addition, a comprehensive literature review of post-distraction ankylosis of TMJs in patients with Nager syndrome was performed. Few studies demonstrated the condition of TMJs after mandibular distraction osteogenesis, and three studies were identified from the review. One study reported ankylosis of bilateral coronoid processes, in which coronoidectomies were necessary. Another study reported the use of prostheses to replace the ankylosed joints in a patient who had undergone many surgeries of the joints, such as gap arthroplasties, reconstructions with costochondral grafts, etc. One other study raised the concept of unloading the condyles during the mandibular distraction to prevent subsequent ankylosis. It seems that multiple factors are related to the ankylosis of TMJs after mandibular distraction osteogenesis in patients with Nager syndrome. Prevention of post-distraction ankylosis of the joints is important because the treatment is difficult and not always effective. We should conduct more studies about protection of the joints during mandibular distraction in the future.
[Mh] Termos MeSH primário: Disostose Mandibulofacial/complicações
Micrognatismo
Osteogênese por Distração/efeitos adversos
Articulação Temporomandibular
[Mh] Termos MeSH secundário: Adolescente
Anquilose/etiologia
Criança
Feminino
Seres Humanos
Masculino
Mandíbula/cirurgia
Micrognatismo/etiologia
Micrognatismo/cirurgia
Osteogênese por Distração/métodos
Reoperação/métodos
Articulação Temporomandibular/diagnóstico por imagem
Articulação Temporomandibular/patologia
Articulação Temporomandibular/fisiopatologia
Resultado do Tratamento
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170928
[Lr] Data última revisão:
170928
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170710
[St] Status:MEDLINE



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