Base de dados : MEDLINE
Pesquisa : E04.936.450.825.249 [Categoria DeCS]
Referências encontradas : 380 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 38 ir para página                         

  1 / 380 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29280879
[Au] Autor:Plana NM; Kimberly LL; Parent B; Khouri KS; Diaz-Siso JR; Fryml EM; Motosko CC; Ceradini DJ; Caplan A; Rodriguez ED
[Ad] Endereço:New York, N.Y. From the Hansjörg Wyss Department of Plastic Surgery and the Division of Medical Ethics, New York University Langone Medical Center.
[Ti] Título:The Public Face of Transplantation: The Potential of Education to Expand the Face Donor Pool.
[So] Source:Plast Reconstr Surg;141(1):176-185, 2018 01.
[Is] ISSN:1529-4242
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Despite the growing success of facial transplantation, organ donor shortages remain challenging. Educational health campaigns can effectively inform the general public and institute behavioral modifications. A brief educational introduction to facial transplantation may positively influence the public's position on facial donation. METHODS: The authors anonymously surveyed 300 participants, gathering basic demographic information, donor registration status, awareness of facial transplantation, and willingness to donate solid organs and facial allografts. Two-hundred of these participants were presented an educational video and subsequently resurveyed on facial donation. Factorial parametric analyses were performed to compare exposure responses before and after watching video exposure. RESULTS: Among participants completing the survey alone (control group), 49 percent were registered donors, 78 percent reported willingness to donate solid organs, and 52 percent reported willingness to donate facial allograft. Of participants who watched the video (video group) 52 percent were registered; 69 and 51 percent were willing to donate solid organs and face, respectively. Following educational intervention, 69 percent of participants in the video group reported willingness to donate facial tissue, an 18 percent increase (p < 0.05), that equated to those willing to donate solid organs. The greatest increase was observed among younger participants (23 percent); women (22 percent); Jewish (22 percent), Catholic (22 percent), and black/African American (25 percent) participants; and respondents holding a higher degree. No significant differences according to gender or ethnicity were observed. CONCLUSION: Educational interventions hold much promise for increasing the general public's awareness of facial transplantation and willingness to participate in donation of facial allografts.
[Mh] Termos MeSH primário: Transplante de Face/psicologia
Educação em Saúde/métodos
Conhecimentos, Atitudes e Prática em Saúde
Doadores de Tecidos/psicologia
Obtenção de Tecidos e Órgãos/métodos
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Idoso de 80 Anos ou mais
Feminino
Seres Humanos
Masculino
Meia-Idade
Cidade de Nova Iorque
Inquéritos e Questionários
Gravação em Vídeo
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; VIDEO-AUDIO MEDIA
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180112
[Lr] Data última revisão:
180112
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171228
[St] Status:MEDLINE
[do] DOI:10.1097/PRS.0000000000003954


  2 / 380 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28742686
[Au] Autor:Duisit J; Maistriaux L; Taddeo A; Orlando G; Joris V; Coche E; Behets C; Lerut J; Dessy C; Cossu G; Vögelin E; Rieben R; Gianello P; Lengelé B
[Ad] Endereço:*Pole of Morphology, Institute of Experimental and Clinical Research, Université catholique de Louvain, Brussels, Belgium †Pole of Experimental Surgery and Transplantation, Institute of Experimental and Clinical Research, Université catholique de Louvain, Brussels, Belgium ‡Department of Plastic and Reconstructive Surgery, Cliniques Universitaires Saint-Luc, Université catholique de Louvain, Brussels, Belgium §Department for Biomedical Research, University of Bern, Bern, Switzerland ¶Department of Surgery, Section of Transplantation, Wake Forest School of Medicine, Winston-Salem, NC ||Pole of Pharmacology and Therapeutic, Institute of Experimental and Clinical Research, Université catholique de Louvain, Brussels, Belgium **Department of Medical Imaging, Cliniques Universitaires Saint-Luc, Université catholique de Louvain, Brussels, Belgium ††Division of Cell Matrix Biology and Regenerative Medicine, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK ‡‡Department of Plastic, Reconstructive and Hand Surgery, Inselspital, University Hospital of Bern, Bern, Switzerland.
[Ti] Título:Bioengineering a Human Face Graft: The Matrix of Identity.
[So] Source:Ann Surg;266(5):754-764, 2017 11.
[Is] ISSN:1528-1140
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: During the last decade, face allotransplantation has been shown to be a revolutionary reconstructive procedure for severe disfigurements. However, offer to patients remains limited due to lifelong immunosuppression. To move forward in the field, a new pathway in tissue engineering is proposed. BACKGROUND: Our previously reported technique of matrix production of a porcine auricular subunit graft has been translated to a human face model. METHODS: 5 partial and 1 total face grafts were procured from human fresh cadavers. After arterial cannulation, the specimens were perfused using a combined detergent/polar solvent decellularization protocol. Preservation of vascular patency was assessed by imaging, cell and antigen removal by DNA quantification and histology. The main extracellular matrix proteins and associated cytokines were evaluated. Lip scaffolds were cultivated with dermal, muscle progenitor and endothelial cells, either on discs or in a bioreactor. RESULTS: Decellularization was successful in all facial grafts within 12 days revealing acellular scaffolds with full preservation of innate morphology. Imaging demonstrated a preservation of the entire vascular tree patency. Removal of cells and antigens was confirmed by reduction of DNA and antigen markers negativation. Microscopic evaluation revealed preservation of tissue structures as well as of major proteins. Seeded cells were viable and well distributed within all scaffolds. CONCLUSIONS: Complex acellular facial scaffolds were obtained, preserving simultaneously a cell-friendly extracellular matrix and a perfusable vascular tree. This step will enable further engineering of postmortem facial grafts, thereby offering new perspectives in composite tissue allotransplantation.
[Mh] Termos MeSH primário: Transplante de Face
Engenharia Tecidual/métodos
[Mh] Termos MeSH secundário: Biomarcadores/metabolismo
Reatores Biológicos
Citocinas/metabolismo
Matriz Extracelular/metabolismo
Seres Humanos
Imuno-Histoquímica
Técnicas In Vitro
Peptídeos e Proteínas de Sinalização Intercelular/metabolismo
Perfusão/métodos
Reperfusão/métodos
Tecidos Suporte
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Biomarkers); 0 (Cytokines); 0 (Intercellular Signaling Peptides and Proteins)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171214
[Lr] Data última revisão:
171214
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170726
[St] Status:MEDLINE
[do] DOI:10.1097/SLA.0000000000002396


  3 / 380 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28662790
[Au] Autor:Sweeney N; Allen K; Miller B; Nolan T; Sheerin K
[Ti] Título:Perioperative Nursing Management of Donor and Recipient Patients Undergoing Face Transplantation.
[So] Source:AORN J;106(1):8-19, 2017 Jul.
[Is] ISSN:1878-0369
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Individuals with debilitating facial injuries and deformities have achieved significant improvement of aesthetic form and function after undergoing a face transplantation. The involvement of surgical technologists and perioperative nurses in the care of the recipient and donor plays a critical role in the success of these procedures. There are unique challenges that staff members may be presented with when caring for a donor and recipient undergoing a face transplantation, including less comfort with and knowledge of the surgical procedure and instrumentation, an increased amount of equipment and personnel in the OR, donor and recipient admission and discharge care, and increased shift length. At New York University Langone Medical Center, New York, we have developed a comprehensive process to prepare staff members to care for patients undergoing face transplantation.
[Mh] Termos MeSH primário: Transplante de Face/enfermagem
Assistência Perioperatória/enfermagem
Enfermagem Perioperatória
Doadores de Tecidos
[Mh] Termos MeSH secundário: Seres Humanos
Salas Cirúrgicas/organização & administração
Alta do Paciente
Transplante Homólogo/enfermagem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171020
[Lr] Data última revisão:
171020
[Sb] Subgrupo de revista:IM; N
[Da] Data de entrada para processamento:170701
[St] Status:MEDLINE


  4 / 380 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28654604
[Au] Autor:Plana NM; Diaz-Siso JR; Rodriguez ED
[Ad] Endereço:New York, N.Y. From the Hansjörg Wyss Department of Plastic Surgery, New York University Langone Medical Center.
[Ti] Título:Discussion: First Lower Two-Thirds Osteomyocutaneous Facial Allograft Perfused by a Unilateral Facial Artery: Outcomes and Vascularization at 1 Year after Transplantation.
[So] Source:Plast Reconstr Surg;140(1):168-169, 2017 07.
[Is] ISSN:1529-4242
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Aloenxertos
Transplante de Face
[Mh] Termos MeSH secundário: Artérias
Face
Seres Humanos
Retalhos Cirúrgicos
Transplante Homólogo
[Pt] Tipo de publicação:JOURNAL ARTICLE; COMMENT
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170810
[Lr] Data última revisão:
170810
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170628
[St] Status:MEDLINE
[do] DOI:10.1097/PRS.0000000000003287


  5 / 380 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28351610
[Au] Autor:De Letter M; Vanhoutte S; Aerts A; Santens P; Vermeersch H; Roche N; Stillaert F; Blondeel P; Van Lierde K
[Ad] Endereço:Department of Speech, Language and Hearing Sciences, Ghent University, Belgium; Department of Neurology, Ghent University Hospital, Belgium. Electronic address: miet.deletter@ugent.be.
[Ti] Título:Facial nerve regeneration after facial allotransplantation: A longitudinal clinical and electromyographic follow-up of lip movements during speech.
[So] Source:J Plast Reconstr Aesthet Surg;70(6):729-733, 2017 Jun.
[Is] ISSN:1878-0539
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: Facial allotransplantation constitutes a reconstructive option after extensive damage to facial structures. Functional recovery has been reported but remains an issue. CASE REPORT - METHODS: A patient underwent facial allotransplantation after a ballistic injury with extensive facial tissue damage. Speech motor function was sequentially assessed clinically, along with repeated electromyography of lip movements during a follow-up of 3 years. RESULTS: Facial nerve recovery could be demonstrated within the first month, followed by a gradual increase in electromyographic amplitude and decrease in reaction times. These were accompanied by gradual improvement of clinical assessments. CONCLUSIONS: Axonal recovery starts early after transplantation. Electromyographic testing is sensitive in demonstrating this early recovery, which ultimately results in clinical improvements.
[Mh] Termos MeSH primário: Nervo Facial/fisiologia
Nervo Facial/cirurgia
Transplante de Face
Lábio/fisiologia
Regeneração Nervosa
Fala/fisiologia
[Mh] Termos MeSH secundário: Eletromiografia
Eletrofisiologia
Seres Humanos
Masculino
Meia-Idade
Movimento
Tempo de Reação
Recuperação de Função Fisiológica
Inteligibilidade da Fala/fisiologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170803
[Lr] Data última revisão:
170803
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170330
[St] Status:MEDLINE


  6 / 380 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28340666
[Au] Autor:Suchyta M; Mardini S
[Ad] Endereço:Division of Plastic and Reconstructive Surgery, Mayo Clinic, MA1244W, 200 First Street Southwest, Rochester, MN 55905, USA.
[Ti] Título:Innovations and Future Directions in Head and Neck Microsurgical Reconstruction.
[So] Source:Clin Plast Surg;44(2):325-344, 2017 Apr.
[Is] ISSN:1558-0504
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Head and neck reconstructive microsurgery is constantly innovating because of a combination of multidisciplinary advances. This article examines recent innovations that have affected the field as well as presenting research leading to future advancement. Innovations include the use of virtual surgical planning and three-dimensional printing in craniofacial reconstruction, advances in intraoperative navigation and imaging, as well as postoperative monitoring, development of minimally invasive reconstructive microsurgery techniques, integration of regenerative medicine and stem cell biology with reconstruction, and the dramatic advancement of face transplant.
[Mh] Termos MeSH primário: Microcirurgia/métodos
Procedimentos Cirúrgicos Reconstrutivos/métodos
[Mh] Termos MeSH secundário: Transplante de Face
Seres Humanos
Cirurgia Assistida por Computador
Retalhos Cirúrgicos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170613
[Lr] Data última revisão:
170613
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170326
[St] Status:MEDLINE


  7 / 380 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28303433
[Au] Autor:Siemionow M
[Ad] Endereço:Department of Orthopaedics, University of Illinois at Chicago, Chicago, USA. siemiom@uic.edu.
[Ti] Título:The decade of face transplant outcomes.
[So] Source:J Mater Sci Mater Med;28(5):64, 2017 May.
[Is] ISSN:1573-4838
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:At the 10th year anniversary of the first face transplantation, 37 patients worldwide, were the recipients of faces coming from human donors. Five patients died due to complications, noncompliance with immunosuppressive medications and development of cancer. Despite the initial debates and ethical concerns, face transplantation became a clinical reality with satisfactory functional outcomes. The areas of controversy still include the impact of life-long immunosuppression on otherwise healthy patients as well as the selection process of face transplant candidates. Other concerns include financial support for this new generation of transplants as well as social re-integration and patients return to work after face transplantation. Based on over 20 years of research experience in the field of vascularized composite allotransplantation (VCA), and clinical experience as a leading surgeon of the US first face transplantation, this review will summarize the well-known facts as well as unexpected outcomes and challenges of face transplantation.
[Mh] Termos MeSH primário: Transplante de Face
[Mh] Termos MeSH secundário: Transplante de Face/efeitos adversos
Transplante de Face/métodos
Transplante de Face/reabilitação
Seres Humanos
Imunossupressão
Seleção de Pacientes
Complicações Pós-Operatórias/etiologia
Resultado do Tratamento
Alotransplante de Tecidos Compostos Vascularizados
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1708
[Cu] Atualização por classe:171021
[Lr] Data última revisão:
171021
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170318
[St] Status:MEDLINE
[do] DOI:10.1007/s10856-017-5873-z


  8 / 380 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28234853
[Au] Autor:Plana NM; Diaz-Siso JR; Rodriguez ED
[Ad] Endereço:From the Hansjörg Wyss Department of Plastic Surgery, New York University Langone Medical Center.
[Ti] Título:Discussion: Watershed Areas in Face Transplantation.
[So] Source:Plast Reconstr Surg;139(3):722-723, 2017 03.
[Is] ISSN:1529-4242
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Transplante de Face
[Mh] Termos MeSH secundário: Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE; COMMENT
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170810
[Lr] Data última revisão:
170810
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170225
[St] Status:MEDLINE
[do] DOI:10.1097/PRS.0000000000003131


  9 / 380 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28234852
[Au] Autor:Bassiri Gharb B; Frautschi RS; Halasa BC; Doumit GD; Djohan RS; Bernard SL; Gastman BR; Siemionow MZ; Papay FA; Rampazzo A
[Ad] Endereço:Cleveland, Ohio; and Chicago, Ill. From the Department of Plastic Surgery, Cleveland Clinic; and the Department of Orthopaedics, University of Illinois.
[Ti] Título:Watershed Areas in Face Transplantation.
[So] Source:Plast Reconstr Surg;139(3):711-721, 2017 Mar.
[Is] ISSN:1529-4242
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The maxillary artery has traditionally been considered the main blood supply of the facial skeleton. However, the deep and concealed location makes the harvest of facial allografts based on this artery challenging, giving preference to the facial artery. There is growing evidence that the junction between the hard and soft palate may represent a watershed area in facial artery-based allografts. The aim of this study was to review the occurrence of partial allograft necrosis and modify the available craniofacial techniques, allowing for a reliable harvest of maxillary artery-based facial allografts. METHODS: PubMed/MEDLINE databases were searched for articles presenting allograft perfusion details and the occurrence of partial flap necrosis. Next, 25 fresh cadaver heads were used: eight allografts were harvested by means of a traditional Le Fort III approach, in six the maxillary artery was injected with latex, in three cadaver heads lead oxide gel was injected in the maxillary artery, and eight full facial allografts were harvested through a modified approach. RESULTS: Seven patients developed palatal fistulas or palatal necrosis (41 percent) when allograft was perfused through the facial artery. The traditional Le Fort III approach demonstrated consistent injury to maxillary artery/branches. The modified approach allowed for preservation of the maxillary artery under direct vision. CONCLUSIONS: Current facial transplantation outcomes indicate that facial artery-based allografts containing Le Fort III bony components can experience compromised palate perfusion. The described modified Le Fort III approach allowed safe dissection of the maxillary artery, preserving the arterial blood supply to the facial skeleton. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, V.
[Mh] Termos MeSH primário: Face/irrigação sanguínea
Transplante de Face/métodos
[Mh] Termos MeSH secundário: Adulto
Cadáver
Feminino
Seres Humanos
Masculino
Artéria Maxilar
Meia-Idade
Veias
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170809
[Lr] Data última revisão:
170809
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170225
[St] Status:MEDLINE
[do] DOI:10.1097/PRS.0000000000003130


  10 / 380 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
[PMID]:28138125
[Au] Autor:Krakowczyk L; Maciejewski A; Szymczyk C; Oles K; Póltorak S
[Ad] Endereço:Department of Oncological and Reconstructive Surgery, Cancer Center, Institute of Maria Sklodowska-Curie in Gliwice, Gliwice, Poland.
[Ti] Título:Face Transplant in an Advanced Neurofibromatosis Type 1 Patient.
[So] Source:Ann Transplant;22:53-57, 2017 Jan 31.
[Is] ISSN:2329-0358
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND The human face is a one-of-a-kind structure with unique morphology, complexity, and function, in which different subunits are not even similar to other parts of the body. Therefore, extended complex deficits of the face are usually difficult to reconstruct, and autologous tissue restoration is generally not able to give a satisfactory aesthetic and functional outcome. The main goal of face allotransplantation is to restore symmetry, contour, and appearance as well as function of the face, especially control of orbicularis oculi and oris muscle physiology. We present the case of a total face transplant in an advanced neurofibromatosis type 1 patient - the second face transplant in Poland. CASE REPORT The recipient was a 28-year-old female with neurofibromatosis type I limited to the head region. During 24 years she underwent more than 35 surgical procedures, but for the last 3 years a significant decrease of her functionality and appearance was observed, including serious problems with speech, eating, and vision. In December 2013 she was qualified for a face transplant procedure. When the donor was found, she was matched on several clinical and biochemical characteristics including negative T and B cell cross-matching. Similarly, the transplantation procedure was done using two connected operating rooms; in the first, the donor's face was harvested, and in the second, the recipient's face was prepared - the tumor mass was resected and vascular and nervous structures were prepared. Due to the extension and complexity of the potential defect, more than 75% of head soft tissues were harvested including both auriculae, left and right eyelids, and scalp down to the occipital lower line. CONCLUSIONS Our case showed that neurofibromatosis is a real indication for a face transplantation procedure. Also, the results of rehabilitation, quality of life, motor and sensory recovery, and physiological status were comparable, showing that face transplantation based on careful selection of recipients and procedure planning is a real alternative, allowing achievement of excellent results that are far away from the outcomes of conventional reconstructions.
[Mh] Termos MeSH primário: Transplante de Face
Neurofibromatose 1/cirurgia
Qualidade de Vida
[Mh] Termos MeSH secundário: Adulto
Feminino
Seres Humanos
Imunossupressores/uso terapêutico
Resultado do Tratamento
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Immunosuppressive Agents)
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170201
[St] Status:MEDLINE



página 1 de 38 ir para página                         
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde