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[PMID]:29320144
[Au] Autor:Lajnert V; Grzic R; Radica N; Snjaric D; Spalj S
[Ti] Título:Translation and validation of the Croatian version of the Oral Impacts on Daily Performances (OIDP) scale.
[So] Source:Vojnosanit Pregl;73(9):811-6, 2016 Sep.
[Is] ISSN:0042-8450
[Cp] País de publicação:Serbia
[La] Idioma:eng
[Ab] Resumo:Background/Aim: Among numerous sociodental indicators the Oral Impacts on Daily Performance (OIPD) is one of the most broadly applied. The aim of this study was to develop and test psychometric properties of a Croatian version of OIDP scale. Methods: The OIDP instrument was translated from English to Croatian in a forward-backward method. The Croatian version was tested for reliability, construct validity and responsiveness on a sample of 702 participants (255 men), aged 18-86 years. Results: Internal consistency of Croatian version of the OIDP was acceptable (alpha = 0.80) and 69.4% of the examinees had oral impacts relating to one or several performances. The most frequently affected performance was eating (53.7%). The test-retest reliability was high (r = 0.99; 95% CI: 0.97-0.99), the mean difference between the OIDP summary scores in two-week interval was not statistically significant. In construct validity testing there was statistically significant correlation between OIDP and self-assessed general and oral health, somatisation, depression and Oral Health Impact Profile ranging from 0.157 to 0.516. Responsiveness was confirmed by a significant reduction of oral impacts on daily performances in subjects before and after treatment of acute dental pain (p < 0.001). Conclusion: The Croatian OIDP index showed good psychometric properties in terms of construct validity, internal consistency, test-retest reliability and responsiveness confirming its appropriateness for use among Croatian population.
[Mh] Termos MeSH primário: Atividades Cotidianas
Avaliação do Impacto na Saúde
Saúde Bucal
Qualidade de Vida
Inquéritos e Questionários
Tradução
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Idoso de 80 Anos ou mais
Croácia
Ingestão de Alimentos
Feminino
Seres Humanos
Masculino
Meia-Idade
Valor Preditivo dos Testes
Psicometria
Reprodutibilidade dos Testes
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; VALIDATION STUDIES
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180213
[Lr] Data última revisão:
180213
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180111
[St] Status:MEDLINE
[do] DOI:10.2298/VSP140829136L


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[PMID]:29182636
[Au] Autor:Hendriksen MAH; Geleijnse JM; van Raaij JMA; Cappuccio FP; Cobiac LC; Scarborough P; Nusselder WJ; Jaccard A; Boshuizen HC
[Ad] Endereço:National Institute for Public Health and the Environment, Bilthoven, the Netherlands.
[Ti] Título:Identification of differences in health impact modelling of salt reduction.
[So] Source:PLoS One;12(11):e0186760, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:We examined whether specific input data and assumptions explain outcome differences in otherwise comparable health impact assessment models. Seven population health models estimating the impact of salt reduction on morbidity and mortality in western populations were compared on four sets of key features, their underlying assumptions and input data. Next, assumptions and input data were varied one by one in a default approach (the DYNAMO-HIA model) to examine how it influences the estimated health impact. Major differences in outcome were related to the size and shape of the dose-response relation between salt and blood pressure and blood pressure and disease. Modifying the effect sizes in the salt to health association resulted in the largest change in health impact estimates (33% lower), whereas other changes had less influence. Differences in health impact assessment model structure and input data may affect the health impact estimate. Therefore, clearly defined assumptions and transparent reporting for different models is crucial. However, the estimated impact of salt reduction was substantial in all of the models used, emphasizing the need for public health actions.
[Mh] Termos MeSH primário: Avaliação do Impacto na Saúde
Cloreto de Sódio na Dieta/administração & dosagem
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Idoso de 80 Anos ou mais
Relação Dose-Resposta a Droga
Feminino
Seres Humanos
Masculino
Meia-Idade
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Sodium Chloride, Dietary)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171226
[Lr] Data última revisão:
171226
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171129
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0186760


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[PMID]:28937960
[Au] Autor:Philippat C; Nakiwala D; Calafat AM; Botton J; De Agostini M; Heude B; Slama R; EDEN Mother­Child Study Group
[Ad] Endereço:Institute for Advanced Biosciences, INSERM U1209, CNRS UMR 5309, University Grenoble Alpes , Grenoble, France.
[Ti] Título:Prenatal Exposure to Nonpersistent Endocrine Disruptors and Behavior in Boys at 3 and 5 Years.
[So] Source:Environ Health Perspect;125(9):097014, 2017 Sep 15.
[Is] ISSN:1552-9924
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Sex-specific associations have been reported between phthalates, bisphenol A (BPA), and child behavior. No data on large study populations are available for other phenols with possible endocrine-disrupting properties. OBJECTIVES: We aimed to study associations between prenatal exposure to phthalates and several phenols on behavior among male infants. METHODS: We quantified 11 phthalate metabolites and nine phenols (four parabens, benzophenone-3, BPA, two dichlorophenols, triclosan) in spot urine samples collected during pregnancy among EDEN cohort mothers who delivered a boy. Mothers completed the Strength and Difficulties Questionnaire (SDQ) when their children were 3.1 (n=529) and 5.6 (n=464) y old. RESULTS: BPA was positively associated with the relationship problems subscale at 3 y [incidence rate ratio (IRR): 1.11; 95% confidence interval (CI): 1.03, 1.20] and the hyperactivity-inattention subscale scores at 5 y (IRR: 1.08; 95% CI: 1.01, 1.14). Mono- -butyl phthalate (MnBP) was positively associated with internalizing behavior, relationship problem, and emotional symptom scores at 3 y. Monobenzyl phthalate (MBzP) was positively associated with internalizing behavior and relationship problems scores at 3 y. After dichotomizing SDQ scores, triclosan tended to be positively associated with emotional symptom subscales at both 3 and 5 y. CONCLUSIONS: The observed associations between BPA, MnBP, and behavior in boys are consistent with previous findings. Further health impact assessment studies based on dose-response functions corrected for exposure misclassification are required to quantify the public health burden possibly entailed by such associations. https://doi.org/10.1289/EHP1314.
[Mh] Termos MeSH primário: Comportamento Infantil/efeitos dos fármacos
Disruptores Endócrinos/urina
Poluentes Ambientais/urina
Ácidos Ftálicos/urina
Efeitos Tardios da Exposição Pré-Natal/epidemiologia
[Mh] Termos MeSH secundário: Criança
Emoções
Disruptores Endócrinos/toxicidade
Poluentes Ambientais/toxicidade
Feminino
Avaliação do Impacto na Saúde
Seres Humanos
Masculino
Ácidos Ftálicos/toxicidade
Gravidez
Efeitos Tardios da Exposição Pré-Natal/urina
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Endocrine Disruptors); 0 (Environmental Pollutants); 0 (Phthalic Acids); 6O7F7IX66E (phthalic acid)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171027
[Lr] Data última revisão:
171027
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170923
[St] Status:MEDLINE
[do] DOI:10.1289/EHP1314


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[PMID]:28640028
[Au] Autor:Guthrie S; Krapels J; Adams A; Alberti P; Bonham A; Garrod B; Esmond S; Scott C; Cochrane G; Wooding S
[Ad] Endereço:S. Guthrie is research leader, RAND Europe, Cambridge, United Kingdom. J. Krapels is senior analyst, RAND Europe, Cambridge, United Kingdom; ORCID: http://orcid.org/0000-0003-0891-6083. A. Adams is director, Center for American Indian and Rural Health Equity, Montana State University, Bozeman, Montana. At the time of the research presented here, she served as director, Collaborative Center for Health Equity, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin. P. Alberti is senior director, Health Equity Research and Policy, Association of American Medical Colleges, Washington, DC. A. Bonham is former chief scientific officer, Association of American Medical Colleges, Washington, DC. B. Garrod is senior analyst, RAND Europe, Cambridge, United Kingdom; ORCID: http://orcid.org/0000-0001-7634-2590. S. Esmond is administrative director, Collaborative Center for Health Equity, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin. C. Scott is health equity outreach specialist, Collaborative Center for Health Equity, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin. G. Cochrane is senior analyst, RAND Europe, Cambridge, United Kingdom. S. Wooding is lead for research and analysis, Centre for Science and Policy, University of Cambridge, Cambridge, United Kingdom; ORCID: http://orcid.org/0000-0002-8036-1054.
[Ti] Título:Assessing and Communicating the Value of Biomedical Research: Results From a Pilot Study.
[So] Source:Acad Med;92(10):1456-1463, 2017 Oct.
[Is] ISSN:1938-808X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PURPOSE: Assessing the impact of research requires an approach that is sensitive both to the context of the research and the perspective of the stakeholders trying to understand its benefits. Here, the authors report on a pilot that applied such an approach to research conducted at the Collaborative Center for Health Equity (CCHE) of the University of Wisconsin School of Medicine and Public Health. METHOD: The pilot assessed the academic impact of CCHE's work; the networks between CCHE and community partners; and the reach of CCHE's programs, including an attempt to estimate return on investment (ROI). Data included bibliometrics, findings from a stakeholder survey and in-depth interviews, and financial figures. RESULTS: The pilot illustrated how CCHE programs increase the capacity of community partners to advocate for their communities and engage with researchers to ensure that research benefits the community. The results illustrate the reach of CCHE's programs into the community. The authors produced an estimate of the ROI for one CCHE program targeting childhood obesity, and values ranged from negative to positive. CONCLUSIONS: The authors experienced challenges using novel assessment techniques at a small scale including the lack of comparator groups and the scarcity of cost data for estimating ROI. This pilot demonstrated the value of research from a variety of perspectives-from academic to community. It illustrates how metrics beyond grant income and publications can capture the outputs of an academic health center in a way that may better align with the aims of the center and stakeholders.
[Mh] Termos MeSH primário: Bibliometria
Pesquisa Biomédica
Relações Comunidade-Instituição
Avaliação do Impacto na Saúde/métodos
Promoção da Saúde/estatística & dados numéricos
[Mh] Termos MeSH secundário: Comportamento Cooperativo
Promoção da Saúde/organização & administração
Seres Humanos
Obesidade Pediátrica
Projetos Piloto
Apoio à Pesquisa como Assunto
Universidades
Wisconsin
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171004
[Lr] Data última revisão:
171004
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170623
[St] Status:MEDLINE
[do] DOI:10.1097/ACM.0000000000001769


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[PMID]:28609433
[Au] Autor:Cherrie JW; Hutchings S; Gorman Ng M; Mistry R; Corden C; Lamb J; Sánchez Jiménez A; Shafrir A; Sobey M; van Tongeren M; Rushton L
[Ad] Endereço:Institute of Occupational Medicine, Research Avenue North, Edinburgh EH14 4AP, UK.
[Ti] Título:Prioritising action on occupational carcinogens in Europe: a socioeconomic and health impact assessment.
[So] Source:Br J Cancer;117(2):274-281, 2017 Jul 11.
[Is] ISSN:1532-1827
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Work-related cancer is an important public health issue with a large financial impact on society. The key European legislative instrument is the Carcinogens and Mutagens Directive (2004/37/EC). In preparation for updating the Directive, the European Commission commissioned a study to provide a socioeconomic, health and environmental impact assessment. METHODS: The evaluation was undertaken for 25 preselected hazardous substances or mixtures. Estimates were made of the number of cases of cancer attributable to workplace exposure, both currently and in the future, with and without any regulatory interventions, and these data were used to estimate the financial health costs and benefits. RESULTS: It was estimated that if no action is taken there will be >700 000 attributable cancer deaths over the next 60 years for the substances assessed. However, there are only seven substances where the data suggest a clear benefit in terms of avoided cancer cases from introducing a binding limit at the levels considered. Overall, the costs of the proposed interventions were very high (up to [euro ]34 000 million) and the associated monetised health benefits were mostly less than the compliance costs. CONCLUSIONS: The strongest cases for the introduction of a limit value are for: respirable crystalline silica, hexavalent chromium, and hardwood dust.
[Mh] Termos MeSH primário: Carcinógenos/toxicidade
Neoplasias/epidemiologia
Exposição Ocupacional/efeitos adversos
Dióxido de Silício/toxicidade
[Mh] Termos MeSH secundário: Cromo/toxicidade
Poeira
Europa (Continente)
Custos de Cuidados de Saúde
Avaliação do Impacto na Saúde/economia
Seres Humanos
Neoplasias/induzido quimicamente
Neoplasias/economia
Neoplasias/patologia
Exposição Ocupacional/economia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Carcinogens); 0 (Dust); 0R0008Q3JB (Chromium); 18540-29-9 (chromium hexavalent ion); 7631-86-9 (Silicon Dioxide)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170614
[St] Status:MEDLINE
[do] DOI:10.1038/bjc.2017.161


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[PMID]:28555396
[Au] Autor:Miri M; Ebrahimi Aval H; Ehrampoush MH; Mohammadi A; Toolabi A; Nikonahad A; Derakhshan Z; Abdollahnejad A
[Ad] Endereço:Department of Environmental Health, School of Public Health, Sabzevar University of Medical Sciences, Sabzevar, Iran. mammadmiry28@gamil.com.
[Ti] Título:Human health impact assessment of exposure to particulate matter: an AirQ software modeling.
[So] Source:Environ Sci Pollut Res Int;24(19):16513-16519, 2017 Jul.
[Is] ISSN:1614-7499
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:The aim of this study was to assess the health impacts related to particulate matter less than 10 µm (PM ) exposure in the city of Yazd, Iran. For this aim, AirQ 2.2.3 software was used to model relationship between short-term exposure to PM and disease cases proposed by the World Health Organization (WHO). The annual mean concentration of PM was 97 µg/m . The maximum concentration value of PM was measured during the summer (731 µg/m ). 4.988% (95%CI: 3.381-6.542%) of the total mortality, 7.3% (95%CI; 4.19-10.21%) of cardiovascular mortality, and 10.21% (95%CI; 4.19-14.89%) of respiratory mortality were related to the PM concentrations. Consequently, the AirQ software can provide valuable information about the importance of air pollution and the substantial impacts of PM on the society for policymakers.
[Mh] Termos MeSH primário: Poluição do Ar/efeitos adversos
Avaliação do Impacto na Saúde
Material Particulado/efeitos adversos
[Mh] Termos MeSH secundário: Poluentes Atmosféricos
Doenças Cardiovasculares/mortalidade
Cidades
Seres Humanos
Irã (Geográfico)
Software
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Air Pollutants); 0 (Particulate Matter)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171109
[Lr] Data última revisão:
171109
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170531
[St] Status:MEDLINE
[do] DOI:10.1007/s11356-017-9189-9


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[PMID]:28490332
[Au] Autor:Elsman EBM; van Nispen RMA; van Rens GHMB
[Ad] Endereço:Department of Ophthalmology, VU University Medical Centre and the Amsterdam Public Health research institute, PO Box 7057, 1007 MB, Amsterdam, The Netherlands. e.elsman@vumc.nl.
[Ti] Título:Feasibility of the Participation and Activity Inventory for Children and Youth (PAI-CY) and Young Adults (PAI-YA) with a visual impairment: a pilot study.
[So] Source:Health Qual Life Outcomes;15(1):98, 2017 May 11.
[Is] ISSN:1477-7525
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Having a visual impairment affects quality of life, daily functioning and participation. To assess rehabilitation needs of visually impaired children and young adults, the Participation and Activity Inventory for Children and Youth (PAI-CY) and Young Adults (PAI-YA) were developed. The PAI-CY comprises four questionnaires for different age categories: 0-2 years, 3-6 years, 7-12 years and 13-17 years. This pilot study assesses the feasibility and acceptability of the PAI-CY and PAI-YA, and the relevance of the content of the questionnaires. METHODS: In addition to the regular admission procedure, the PAI-CY and PAI-YA were completed by 30 participants (six per questionnaire). For the PAI-CY, parents completed the questionnaire online prior to admission. From age 7 years onwards, children completed the questionnaire face-to-face with a rehabilitation professional during the admission procedure. Young adults completed the PAI-YA online. Subsequently, participants and professionals administered an evaluation form. RESULTS: Overall, 85% of the parents rated all aspects of the PAI-CY neutral to positive, whereas 100% of all children and young adults were neutral to positive on all aspects, except for the duration to complete. The main criticism of professionals was that they were unable to identify actual rehabilitation needs using the questionnaires. Minor adjustments were recommended for the content of questions. CONCLUSIONS: Parents, children and young adults were mostly satisfied with the questionnaires, however, professionals suggested some changes. The adaptations made should improve satisfaction with content, clarification of questions, and satisfaction with the questionnaires in compiling a rehabilitation plan. Although face and content validity has been optimized, a larger field study is taking place to further develop and evaluate the questionnaires.
[Mh] Termos MeSH primário: Avaliação do Impacto na Saúde/métodos
Qualidade de Vida
Inquéritos e Questionários
Transtornos da Visão/psicologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Criança
Pré-Escolar
Estudos de Viabilidade
Feminino
Seres Humanos
Masculino
Pais
Projetos Piloto
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; VALIDATION STUDIES
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170830
[Lr] Data última revisão:
170830
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170512
[St] Status:MEDLINE
[do] DOI:10.1186/s12955-017-0677-x


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[PMID]:28410806
[Au] Autor:Yin H; Pizzol M; Xu L
[Ad] Endereço:State Key Laboratory of Environmental Simulation and Pollution Control, School of Environment, Beijing Normal University, No. 19, Xinjiekouwai Street, Haidian District, Beijing 100875, China; Department of Development and Planning, Danish Centre for Environmental Assessment, Aalborg University, Rendsburggade 14, 9000 Aalborg, Denmark.
[Ti] Título:External costs of PM2.5 pollution in Beijing, China: Uncertainty analysis of multiple health impacts and costs.
[So] Source:Environ Pollut;226:356-369, 2017 Jul.
[Is] ISSN:1873-6424
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Some cities in China are facing serious air pollution problems including high concentrations of particles, SO and NO . Exposure to PM2.5, one of the primary air pollutants in many cities in China, is highly correlated with various adverse health impacts and ultimately represents a cost for society. The aim of this study is to assess health impacts and external costs related to PM2.5 pollution in Beijing, China with different baseline concentrations and valuation methods. The idea is to provide a reasonable estimate of the total health impacts and external cost due to PM2.5 pollution, as well as a quantification of the relevant uncertainty. PM2.5 concentrations were retrieved for the entire 2012 period in 16 districts of Beijing. The various PM2.5 related health impacts were identified and classified to avoid double counting. Exposure-response coefficients were then obtained from literature. Both the value of statistical life (VSL) and the amended human capital (AHC) approach were applied for external costs estimation, which could provide the upper and lower bound of the external costs due to PM2.5. To fully understand the uncertainty levels, the external cost distribution was determined via Monte Carlo simulation based on the uncertainty of the parameters such as PM2.5 concentration, exposure-response coefficients, and economic cost per case. The results showed that the external costs were equivalent to around 0.3% (AHC, China's guideline: C = 35 µg/m ) to 0.9% (VSL, WHO guideline: C = 10 µg/m ) of regional GDP depending on the valuation method and on the assumed baseline PM2.5 concentration (C ). Among all the health impacts, the economic loss due to premature deaths accounted for more than 80% of the overall external costs. The results of this study could help policymakers prioritizing the PM2.5 pollution control interventions and internalize the external costs through the application of economic policy instruments.
[Mh] Termos MeSH primário: Poluentes Atmosféricos/análise
Poluição do Ar/economia
Exposição Ambiental/economia
Avaliação do Impacto na Saúde
[Mh] Termos MeSH secundário: Poluição do Ar/análise
Pequim
China
Cidades
Exposição Ambiental/estatística & dados numéricos
Seres Humanos
Material Particulado/análise
Incerteza
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Air Pollutants); 0 (Particulate Matter)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170724
[Lr] Data última revisão:
170724
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170416
[St] Status:MEDLINE


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[PMID]:28399801
[Au] Autor:Weidemann F; Remschmidt C; Buda S; Buchholz U; Ultsch B; Wichmann O
[Ad] Endereço:Immunization Unit, Robert Koch-Institute, Seestr. 10, 13359, Berlin, Germany.
[Ti] Título:Is the impact of childhood influenza vaccination less than expected: a transmission modelling study.
[So] Source:BMC Infect Dis;17(1):258, 2017 Apr 11.
[Is] ISSN:1471-2334
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: To reduce the burden of severe influenza, most industrialized countries target specific risk-groups with influenza vaccines, e.g. the elderly or individuals with comorbidities. Since children are the main spreaders, some countries have recently implemented childhood vaccination programs to reduce overall virus transmission and thereby influenza disease in the whole population. The introduction of childhood vaccination programs was often supported by modelling studies that predicted substantial incidence reductions. We developed a mathematical transmission model to examine the potential impact of childhood influenza vaccination in Germany, while also challenging established modelling assumptions. METHODS: We developed an age-stratified SEIR-type transmission model to reproduce the epidemic influenza seasons between 2003/04 and 2013/14. The model was built upon German population counts, contact patterns, and vaccination history and was fitted to seasonal data on influenza-attributable medically attended acute respiratory infections (I-MAARI) and strain distribution using Bayesian methods. As novelties we (i) implemented a stratified model structure enabling seasonal variability and (ii) deviated from the commonly assumed mass-action-principle by employing a phenomenological transmission rate. RESULTS: According to the model, by vaccinating primarily the elderly over ten seasons 4 million (95% prediction interval: 3.84 - 4.19) I-MAARI were prevented which corresponds to an 8.6% (8.3% - 8.9%) reduction compared to a no-vaccination scenario and a number-needed-to-vaccinate (NNV) to prevent one I-MAARI of 37.1 (35.5 - 38.7). Additional vaccination of 2-10 year-old children at 40% coverage would have led to an overall I-MAARI reduction of 17.8% (17.1 - 18.7%) mostly due to indirect effects with a NNV of 20.7 (19.6 - 21.6). When employing the traditional mass-action-principle, the model predicted a more than 3-fold higher I-MAARI reduction (55.6%) due to childhood vaccination. CONCLUSION: In Germany, the introduction of routine childhood influenza vaccination could considerably reduce I-MAARI among all age-groups and improve the NNV. However, the predicted impact is much lower compared to previous studies, which is primarily caused by our phenomenological approach to modelling influenza virus transmission.
[Mh] Termos MeSH primário: Vacinas contra Influenza/imunologia
Influenza Humana/prevenção & controle
[Mh] Termos MeSH secundário: Doença Aguda
Adulto
Teorema de Bayes
Criança
Pré-Escolar
Feminino
Alemanha/epidemiologia
Avaliação do Impacto na Saúde
Seres Humanos
Incidência
Lactente
Influenza Humana/epidemiologia
Influenza Humana/transmissão
Masculino
Meia-Idade
Modelos Biológicos
Estações do Ano
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Influenza Vaccines)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170628
[Lr] Data última revisão:
170628
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170413
[St] Status:MEDLINE
[do] DOI:10.1186/s12879-017-2344-6


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[PMID]:28379930
[Au] Autor:Bonham AC; Alberti PM
[Ad] Endereço:A.C. Bonham is immediate past chief scientific officer, Association of American Medical Colleges, Washington, DC. P.M. Alberti is senior director, Health Equity Research and Policy, Association of American Medical Colleges, Washington, DC.
[Ti] Título:From Inputs to Impacts: Assessing and Communicating the Full Value of Biomedical Research.
[So] Source:Acad Med;92(10):1375-1377, 2017 Oct.
[Is] ISSN:1938-808X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Assessing and communicating the full value of biomedical research is essential to answer calls from the government and the public demanding accountability for the spending of public funds. In academic settings, however, research success is measured largely in terms of grant funding received or the number of peer-reviewed publications produced. These credible and time-tested metrics miss the full picture of the scientific process, which continues to confer benefits to patients, communities, and the health care system well after an article is published. In this context, in 2012, the Association of American Medical Colleges, in collaboration with RAND Europe, initiated a program to provide resources and guidance for leaders of medical schools and teaching hospitals interested in evaluating-in novel ways complementary to traditional methods-the outcomes and impacts of the research that emanates from their institutions. This Perspective provides context for this initiative and delineates the process through which researchers, evaluation experts, and other stakeholders-including legislators, health system leaders, and community members-identified and vetted novel "metrics that matter" in advance of a pilot test at the University of Wisconsin-Madison, which sought to assess and communicate its community-engaged science and scholarship.
[Mh] Termos MeSH primário: Bibliometria
Pesquisa Biomédica
Avaliação do Impacto na Saúde/métodos
Apoio à Pesquisa como Assunto
Responsabilidade Social
[Mh] Termos MeSH secundário: Comportamento Cooperativo
Europa (Continente)
Seres Humanos
Projetos Piloto
Estados Unidos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171004
[Lr] Data última revisão:
171004
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170406
[St] Status:MEDLINE
[do] DOI:10.1097/ACM.0000000000001639



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