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[PMID]:28416009
[Au] Autor:Mwanza M; Zulu J; Topp SM; Musonda P; Mutale W; Chilengi R
[Ad] Endereço:Centre for Infectious Disease Research in Zambia, Plot No. 5032, Great North Road, P.O. Box 34681, Lusaka, Zambia. moses.mwanza@cidrz.org.
[Ti] Título:Use of Lot quality assurance sampling surveys to evaluate community health worker performance in rural Zambia: a case of Luangwa district.
[So] Source:BMC Health Serv Res;17(1):279, 2017 Apr 17.
[Is] ISSN:1472-6963
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The Better Health Outcomes through Mentoring and Assessment (BHOMA) project is a cluster randomized controlled trial aimed at reducing age-standardized mortality rates in three rural districts through involvement of Community Health Workers (CHWs), Traditional Birth Attendants (TBAs), and Neighborhood Health Committees (NHCs). CHWs conduct quarterly surveys on all households using a questionnaire that captures key health events occurring within their catchment population. In order to validate contact with households, we utilize the Lot Quality Assurance Sampling (LQAS) methodology. In this study, we report experiences of applying the LQAS approach to monitor performance of CHWs in Luangwa District. METHODS: Between April 2011 and December 2013, seven health facilities in Luangwa district were enrolled into the BHOMA project. The health facility catchment areas were divided into 33 geographic zones. Quality assurance was performed each quarter by randomly selecting zones representing about 90% of enrolled catchment areas from which 19 households per zone where also randomly identified. The surveys were conducted by CHW supervisors who had been trained on using the LQAS questionnaire. Information collected included household identity number (ID), whether the CHW visited the household, duration of the most recent visit, and what health information was discussed during the CHW visit. The threshold for success was set at 75% household outreach by CHWs in each zone. RESULTS: There are 4,616 total households in the 33 zones. This yielded a target of 32,212 household visits by community health workers during the 7 survey rounds. Based on the set cutoff point for passing the surveys (at least 75% households confirmed as visited), only one team of CHWs at Luangwa high school failed to reach the target during round 1 of the surveys; all the teams otherwise registered successful visits in all the surveys. CONCLUSIONS: We have employed the LQAS methodology for assurance that quarterly surveys were successfully done. This methodology proved helpful in identifying poorly performing CHWs and could be useful for evaluating CHW performance in other areas. TRIAL REGISTRATION: Identifier: NCT01942278 . Date of Registration: September 2013.
[Mh] Termos MeSH primário: Competência Clínica/normas
Agentes Comunitários de Saúde/normas
Amostragem para Garantia da Qualidade de Lotes/utilização
[Mh] Termos MeSH secundário: Adolescente
Adulto
Características da Família
Feminino
Instalações de Saúde
Seres Humanos
Masculino
Tocologia/normas
Gravidez
Cuidado Pré-Natal/normas
Distribuição Espacial da População
Saúde da População Rural
Inquéritos e Questionários
Adulto Jovem
Zâmbia/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; MULTICENTER STUDY; RANDOMIZED CONTROLLED TRIAL
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170531
[Lr] Data última revisão:
170531
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170419
[St] Status:MEDLINE
[do] DOI:10.1186/s12913-017-2229-9


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[PMID]:28339294
[Au] Autor:van Leth F; den Heijer C; Beerepoot M; Stobberingh E; Geerlings S; Schultsz C
[Ad] Endereço:Department of Global Health, Academic Medical Center, University of Amsterdam, Amsterdam Institute for Global Health & Development, Amsterdam, The Netherlands.
[Ti] Título:Rapid assessment of antimicrobial resistance prevalence using a Lot Quality Assurance sampling approach.
[So] Source:Future Microbiol;12:369-377, 2017 Apr.
[Is] ISSN:1746-0921
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:AIM: Increasing antimicrobial resistance (AMR) requires rapid surveillance tools, such as Lot Quality Assurance Sampling (LQAS). MATERIALS & METHODS: LQAS classifies AMR as high or low based on set parameters. We compared classifications with the underlying true AMR prevalence using data on 1335 Escherichia coli isolates from surveys of community-acquired urinary tract infection in women, by assessing operating curves, sensitivity and specificity. RESULTS: Sensitivity and specificity of any set of LQAS parameters was above 99% and between 79 and 90%, respectively. Operating curves showed high concordance of the LQAS classification with true AMR prevalence estimates. CONCLUSION: LQAS-based AMR surveillance is a feasible approach that provides timely and locally relevant estimates, and the necessary information to formulate and evaluate guidelines for empirical treatment.
[Mh] Termos MeSH primário: Anti-Infecciosos/farmacologia
Farmacorresistência Bacteriana
Escherichia coli/efeitos dos fármacos
[Mh] Termos MeSH secundário: Anti-Infecciosos/uso terapêutico
Métodos Epidemiológicos
Escherichia coli/isolamento & purificação
Infecções por Escherichia coli/tratamento farmacológico
Infecções por Escherichia coli/epidemiologia
Infecções por Escherichia coli/microbiologia
Feminino
Seres Humanos
Amostragem para Garantia da Qualidade de Lotes
Prevalência
Sensibilidade e Especificidade
Infecções Urinárias/tratamento farmacológico
Infecções Urinárias/epidemiologia
Infecções Urinárias/microbiologia
[Pt] Tipo de publicação:EVALUATION STUDIES; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Infective Agents)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170421
[Lr] Data última revisão:
170421
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170325
[St] Status:MEDLINE
[do] DOI:10.2217/fmb-2016-0170


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[PMID]:28099655
[Au] Autor:Arroz JA; Chirrute F; Mendis C; Chande MH; Kollhoff V
[Ad] Endereço:World Vision Mozambique. Malaria Project Global Funded. Maputo, Moçambique.
[Ti] Título:Assessment on the ownership and use of mosquito nets in Mozambique.
[So] Source:Rev Saude Publica;50:67, 2016 Dec 22.
[Is] ISSN:1518-8787
[Cp] País de publicação:Brazil
[La] Idioma:eng; por
[Ab] Resumo:OBJECTIVE: To assess the ownership and use of mosquito nets in 2014, in Mozambique. METHODS: This observational and cross-sectional study assessed, in February and March 2015, 69 districts (nine of 11 provinces of Mozambique) that have benefited from the mass distribution of mosquito nets. The Lot Quality Assurance Sampling methodology was used. Each locality was denominated supervision area. The Lot Quality Assurance Sampling opts for a minimum of 19 households (in this case, we decided for a minimum of 100 households per district) from each supervision area to assess an indicator (in this case, two indicators were assessed: ownership and use of mosquito nets). Two questions guided the research: a) received a mosquito net; b) used a mosquito net the night before. RESULTS: A total of 6,725 households were assessed. Eighty three percent of them had received mosquito nets in the campaign. Of the 6,232 respondents, 82.0% said they used mosquito nets the night before. The districts of the provinces with low coverage of ownership and use were Tete (69.5% and 60.0%, respectively), Zambezia (79.0% and 60.0%, respectively), and Gaza (81.6% and 70.7%, respectively). The largest coverage of ownership and use were observed in the districts of Nampula (96.7% and 93.8%, respectively) and Niassa (86.0% and 85.4% respectively). CONCLUSIONS: In the districts assessed, the progression of ownership and use of mosquito nets is satisfactory. Nampula and Niassa are the only provinces where ownership and use are at desired levels. OBJECTIVO: Avaliar a posse e o uso das redes mosquiteiras no ano de 2014 em Moçambique. MÉTODOS: Este estudo observacional transversal avaliou, em fevereiro e março de 2015, 68 distritos (nove das 11 províncias de Moçambique) que se beneficiaram da distribuição de redes em massa. Usou-se a metodologia Lot Quality Assurance Sampling. Cada localidade foi designada de área de supervisão. O Lot Quality Assurance Sampling opta por um mínimo de 19 agregados familiares (neste caso decidiu-se um mínimo de 100 agregados familiares por distrito) de cada área de supervisão, a fim de avaliar um indicador (neste caso dois indicadores foram avaliados: posse e uso de redes mosquiteiras). Duas perguntas nortearam a pesquisa: a) recebeu rede; b) usou rede na noite anterior. RESULTADOS: Foram avaliados 6.725 agregados familiares . Desses, 83,0% tinham recebido redes na campanha. Dos 6.232 inqueridos, 82,0% disseram que usaram na noite anterior. As províncias com distritos com menores coberturas de posse e uso foram Tete (69,5% e 60,0%, respectivamente), Zambézia (79,0% e 60,0%, respectivamente) e Gaza (81,6% e 70,7%, respectivamente). As maiores coberturas de posse e uso foram observadas nos distritos de Nampula (96,7% e 93,8%, respectivamente) e Niassa (86,0% e 85,4%, respectivamente). CONCLUSÕES: Nos distritos avaliados, a progressão para a posse e uso de redes mosquiteiras é satisfatória. Nampula e Niassa são as únicas províncias onde a posse e o uso estão em níveis desejados.
[Mh] Termos MeSH primário: Amostragem para Garantia da Qualidade de Lotes/métodos
Malária/prevenção & controle
Controle de Mosquitos/métodos
Mosquiteiros/utilização
Propriedade/estatística & dados numéricos
[Mh] Termos MeSH secundário: Estudos Transversais
Conhecimentos, Atitudes e Prática em Saúde
Seres Humanos
Mosquiteiros/provisão & distribuição
Moçambique
[Pt] Tipo de publicação:JOURNAL ARTICLE; OBSERVATIONAL STUDY
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170706
[Lr] Data última revisão:
170706
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170119
[St] Status:MEDLINE


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[PMID]:27832211
[Au] Autor:Das A; Mahapatra S; Sai Mala G; Chaudhuri I; Mahapatra T
[Ad] Endereço:CARE India Solutions for Sustainable Development, H No. 14, Patliputra Colony, Patna, Bihar, PIN Code- 800013, India.
[Ti] Título:Association of Frontline Worker-Provided Services with Change in Block-Level Complementary Feeding Indicators: An Ecological Analysis from Bihar, India.
[So] Source:PLoS One;11(11):e0166511, 2016.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Insufficiencies in complementary feeding put infants and young children at increased risk of undernutrition. Till now, most Indian studies have looked at the individual level determinants of complementary feeding practices. We aimed to evaluate the association of frontline worker (FLW) provided nutritional counselling services, with change in community level indicators of complementary feeding practices among 9-11 month old children over time. METHODS: The study data was obtained from five rounds of 'Lot Quality Assurance Sampling' survey in eight districts of Bihar, an impoverished Indian state. The surveys were conducted as evaluation exercises for the 'Integrated Family Health Initiative (IFHI)'-a multi-faceted program aimed at improving the maternal and child health outcomes in Bihar. The main outcome indicators were-current breastfeeding, age-appropriate minimum frequency of semi-solid food, age-appropriate minimum quantity of semi-solid food, initiation of complementary feeding at the right age, and dietary diversity. Repeated measures analysis was performed to determine the association of changes in the outcome indicators with coverage of FLW-provided counselling services. RESULTS: Visits by FLW, advices on age-appropriate frequency and handwashing were significant predictors of receiving age-appropriate frequency of feeding. The determinants of receiving age-appropriate quantity were-advices on age appropriate frequency and advices on handwashing. Receiving food support from AWC and FLW visits were significantly associated with initiating complementary feeding at the right age. CONCLUSIONS: The present study identified the critical elements among the different types of FLW-provided services. The study findings, from an economically and socially underdeveloped region of India, would inform the relevant programs about the nutritional counselling services that need to be emphasized upon for reducing the burden of childhood malnutrition.
[Mh] Termos MeSH primário: Fenômenos Fisiológicos da Nutrição do Lactente
[Mh] Termos MeSH secundário: Dieta
Saúde da Família
Feminino
Seres Humanos
Índia
Lactente
Cuidado do Lactente
Alimentos Infantis
Amostragem para Garantia da Qualidade de Lotes
Necessidades Nutricionais
Fatores Socioeconômicos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170621
[Lr] Data última revisão:
170621
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161111
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0166511


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[PMID]:27757070
[Au] Autor:Pham K; Sharpe EC; Weiss WM; Vu A
[Ad] Endereço:Department of Emergency Medicine, Johns Hopkins School of Medicine, Baltimore, MD USA ; Department of International Health, Center for Refugee and Disaster Response, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD USA.
[Ti] Título:The use of a lot quality assurance sampling methodology to assess and manage primary health interventions in conflict-affected West Darfur, Sudan.
[So] Source:Popul Health Metr;14:34, 2016.
[Is] ISSN:1478-7954
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Organizations working in conflict-affected areas have a need to monitor and evaluate their programs, however this is often difficult due to the logistical challenges of conflict areas. Lot quality assurance sampling may be a suitable method of assessing programs in these situations. METHODS: We conducted a secondary data analysis of information collected during Medair's routine program management functions. Medair's service area in West Darfur, Sudan was divided into seven supervisory areas. Using the available population information, a sampling frame was developed and interviews were conducted from randomly selected caretakers of children in each supervisory area every six months over 19 months. A survey instrument with questions related to key indicators for immunizations and maternal, newborn, and child health was used for the interviews. Based on Medair's goals for each indicator, decision rules were calculated for the indicators; these decision rules determined which supervisory areas and indicators performed adequately in each assessment period. Pearson's chi-squared tests, adjusted for the survey design using STATA "svy: tab" commands, were used to detect overall differences in coverage in this analysis. RESULTS: The coverage of tetanus toxoid vaccination among pregnant women increased from 47.2 to 69.7 % ( value = 0.046), and births attended by a skilled health professional increased from 35.7 to 52.7 % ( value = 0.025) from the first to last assessment periods. Measles vaccinations declined from 72.0 to 54.1 % ( value = 0.046). The estimated coverage for the proportion of women receiving a postpartum dose of vitamin A (54.7 to 61.3 %, value = 0.44); pregnant women receiving a clean delivery kit (54.6 to 47.1 %, value = 0.49); and pentavalent vaccinations (49.7 to 42.1 %, value = 0.28) did not significantly change. CONCLUSIONS: Lot quality assurance sampling was a feasible method for Medair staff to evaluate and optimize primary health programs in a conflict-affected area. Medair managers were able to collect, analyze, and disseminate data to staff alongside the routine work of the organization. These results suggest LQAS may be used in other complex humanitarian emergencies in which there are logistical challenges and limited resources.
[Mh] Termos MeSH primário: Conflitos Armados
Amostragem para Garantia da Qualidade de Lotes/métodos
Serviços de Saúde Materno-Infantil
Avaliação de Programas e Projetos de Saúde/métodos
Garantia da Qualidade dos Cuidados de Saúde
Indicadores de Qualidade em Assistência à Saúde
Vacinação
[Mh] Termos MeSH secundário: Adulto
Criança
Parto Obstétrico/métodos
Feminino
Pesquisas sobre Serviços de Saúde
Seres Humanos
Sarampo/prevenção & controle
Gravidez
Complicações na Gravidez/prevenção & controle
Atenção Primária à Saúde
Amostragem
Sudão
Tétano/prevenção & controle
Vitamina A/administração & dosagem
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
11103-57-4 (Vitamin A)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170913
[Lr] Data última revisão:
170913
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161021
[St] Status:MEDLINE


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[PMID]:27534743
[Au] Autor:Beckworth CA; Anguyo R; Kyakulaga FC; Lwanga SK; Valadez JJ
[Ad] Endereço:Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, L3 5QA, United Kingdom. cbeckworth74@gmail.com.
[Ti] Título:Can local staff reliably assess their own programs? A confirmatory test-retest study of Lot Quality Assurance Sampling data collectors in Uganda.
[So] Source:BMC Health Serv Res;16(1):396, 2016 Aug 17.
[Is] ISSN:1472-6963
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Data collection techniques that routinely provide health system information at the local level are in demand and needed. LQAS is intended for use by local health teams to collect data at the district and sub-district levels. Our question is whether local health staff produce biased results as they are responsible for implementing the programs they also assess. METHODS: This test-retest study replicates on a larger scale an earlier LQAS reliability assessment in Uganda. We conducted in two districts an LQAS survey using 15 local health staff as data collectors. A week later, the data collectors swapped districts, where they acted as disinterested non-local data collectors, repeating the LQAS survey with the same respondents. We analysed the resulting two data sets for agreement using Cohens' Kappa. RESULTS: The average Kappa score for the knowledge indicators was k = 0.43 (SD = 0.16) and for practice indicators k = 0.63 (SD = 0.17). These scores show moderate agreement for knowledge indicators and substantial agreement for practice indicators. Analyses confirm that respondents were more knowledgeable on retest; no evidence of bias was found for practice indicators. CONCLUSION: The findings of this study are remarkably similar to those produced in the first reliability study. There is no evidence that using local healthcare staff to collect LQAS data biases data collection in an LQAS study. The bias observed in the knowledge indicators was most likely due to a 'practice effect', whereby respondents increased their knowledge as a result of completing the first survey; no corresponding effect was seen in the practice indicators.
[Mh] Termos MeSH primário: Garantia da Qualidade dos Cuidados de Saúde/métodos
[Mh] Termos MeSH secundário: Viés
Assistência à Saúde/normas
Pessoal de Saúde/normas
Seres Humanos
Amostragem para Garantia da Qualidade de Lotes
Variações Dependentes do Observador
Indicadores de Qualidade em Assistência à Saúde/normas
Reprodutibilidade dos Testes
Amostragem
Inquéritos e Questionários
Uganda
[Pt] Tipo de publicação:JOURNAL ARTICLE; MULTICENTER STUDY
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160819
[St] Status:MEDLINE
[do] DOI:10.1186/s12913-016-1655-4


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[PMID]:27513642
[Au] Autor:Das A; Chatterjee R; Karthick M; Mahapatra T; Chaudhuri I
[Ad] Endereço:CARE India Solutions for Sustainable Development, H No. 14, Patliputra Colony, Patna, Bihar, India.
[Ti] Título:The Influence of Seasonality and Community-Based Health Worker Provided Counselling on Exclusive Breastfeeding - Findings from a Cross-Sectional Survey in India.
[So] Source:PLoS One;11(8):e0161186, 2016.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Exclusive breastfeeding (EBF) during the first six months of life is considered a high impact but low-cost measure for reducing the morbidity and mortality among children. The current study investigated the association of seasonality and frontline worker(FLW) provided counselling with practice of EBF in Bihar, India. METHODS: We used the 'Lot Quality Assurance Sampling' technique to conduct a multi-stage sampling survey in 8 districts of Bihar. Regarding EBF, mothers of 0-5 (completed) months old children were asked if they had given only breastmilk to their children during the previous day, while mothers of 6-8 (completed) months old children were inquired about the total duration of EBF. We tested for association between EBF during the previous day with season of interview and EBF for full 6 months with nursing season. We also assessed if receiving counselling on EBF and complementary feeding had any association with relevant EBF indicators. RESULTS: Among the under-6 month old children, 76% received EBF during the previous day, whereas 92% of 6-8 (completed) months old children reportedly received EBF for the recommended duration. Proportion of 0-5 (completed) month old children receiving only breastmilk (during last 24 hours) decreased significantly with increasing age and with change of season from colder to warmer months. Odds of receiving only breastmilk during the previous day was significantly higher during the winter months (Adjusted odds ratio(AOR) = 1.50; 95% CI = 1.37, 1.63) compared to summer. Also, the children nursed primarily during the winter season had higher odds of receiving EBF for 6 months (AOR = 1.90, 95% CI = 1.43, 2.52) than those with non-winter nursing. Receiving FLW-counselling was positively associated with breastfeeding exclusively, even after adjusting for seasonality and other covariates (AOR = 1.82; 95% CI = 1.67, 1.98). CONCLUSIONS: Seasonality is a significant but non-modifiable risk factor for EBF. However, FLW-counselling was found to increase practice of EBF irrespective of season. Scale-up of FLW-counselling services, with emphasis on summer months and mothers of older infants, can potentially reduce the impact of seasonality on EBF.
[Mh] Termos MeSH primário: Aleitamento Materno/estatística & dados numéricos
Agentes Comunitários de Saúde
Aconselhamento
Conhecimentos, Atitudes e Prática em Saúde
Estações do Ano
[Mh] Termos MeSH secundário: Adulto
Estudos Transversais
Feminino
Seres Humanos
Índia
Lactente
Fenômenos Fisiológicos da Nutrição do Lactente
Recém-Nascido
Amostragem para Garantia da Qualidade de Lotes
Masculino
Inquéritos e Questionários
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170803
[Lr] Data última revisão:
170803
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160812
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0161186


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[PMID]:27504954
[Au] Autor:Lo NC; Coulibaly JT; Bendavid E; N'Goran EK; Utzinger J; Keiser J; Bogoch II; Andrews JR
[Ad] Endereço:Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, California, United States of America.
[Ti] Título:Evaluation of a Urine Pooling Strategy for the Rapid and Cost-Efficient Prevalence Classification of Schistosomiasis.
[So] Source:PLoS Negl Trop Dis;10(8):e0004894, 2016 Aug.
[Is] ISSN:1935-2735
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: A key epidemiologic feature of schistosomiasis is its focal distribution, which has important implications for the spatial targeting of preventive chemotherapy programs. We evaluated the diagnostic accuracy of a urine pooling strategy using a point-of-care circulating cathodic antigen (POC-CCA) cassette test for detection of Schistosoma mansoni, and employed simulation modeling to test the classification accuracy and efficiency of this strategy in determining where preventive chemotherapy is needed in low-endemicity settings. METHODOLOGY: We performed a cross-sectional study involving 114 children aged 6-15 years in six neighborhoods in Azaguié Ahoua, south Côte d'Ivoire to characterize the sensitivity and specificity of the POC-CCA cassette test with urine samples that were tested individually and in pools of 4, 8, and 12. We used a Bayesian latent class model to estimate test characteristics for individual POC-CCA and quadruplicate Kato-Katz thick smears on stool samples. We then developed a microsimulation model and used lot quality assurance sampling to test the performance, number of tests, and total cost per school for each pooled testing strategy to predict the binary need for school-based preventive chemotherapy using a 10% prevalence threshold for treatment. PRINCIPAL FINDINGS: The sensitivity of the urine pooling strategy for S. mansoni diagnosis using pool sizes of 4, 8, and 12 was 85.9%, 79.5%, and 65.4%, respectively, when POC-CCA trace results were considered positive, and 61.5%, 47.4%, and 30.8% when POC-CCA trace results were considered negative. The modeled specificity ranged from 94.0-97.7% for the urine pooling strategies (when POC-CCA trace results were considered negative). The urine pooling strategy, regardless of the pool size, gave comparable and often superior classification performance to stool microscopy for the same number of tests. The urine pooling strategy with a pool size of 4 reduced the number of tests and total cost compared to classical stool microscopy. CONCLUSIONS/SIGNIFICANCE: This study introduces a method for rapid and efficient S. mansoni prevalence estimation through examining pooled urine samples with POC-CCA as an alternative to widely used stool microscopy.
[Mh] Termos MeSH primário: Antígenos de Helmintos/urina
Sistemas Automatizados de Assistência Junto ao Leito
Schistosoma/isolamento & purificação
Esquistossomose/epidemiologia
Urina/parasitologia
[Mh] Termos MeSH secundário: Adolescente
Animais
Teorema de Bayes
Quimioprevenção/instrumentação
Quimioprevenção/métodos
Criança
Costa do Marfim/epidemiologia
Estudos Transversais
Feminino
Seres Humanos
Amostragem para Garantia da Qualidade de Lotes
Masculino
Prevalência
Kit de Reagentes para Diagnóstico/economia
Schistosoma/imunologia
Esquistossomose/classificação
Esquistossomose/parasitologia
Instituições Acadêmicas/economia
Instituições Acadêmicas/estatística & dados numéricos
Sensibilidade e Especificidade
[Pt] Tipo de publicação:EVALUATION STUDIES; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antigens, Helminth); 0 (Reagent Kits, Diagnostic)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170720
[Lr] Data última revisão:
170720
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160810
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pntd.0004894


  9 / 92 MEDLINE  
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[PMID]:27225791
[Au] Autor:Odaga J; Henriksson DK; Nkolo C; Tibeihaho H; Musabe R; Katusiime M; Sinabulya Z; Mucunguzi S; Mbonye AK; Valadez JJ
[Ad] Endereço:Liverpool School of Tropical Medicine, Kampala, Uganda.
[Ti] Título:Empowering districts to target priorities for improving child health service in Uganda using change management and rapid assessment methods.
[So] Source:Glob Health Action;9:30983, 2016.
[Is] ISSN:1654-9880
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Local health system managers in low- and middle-income countries have the responsibility to set health priorities and allocate resources accordingly. Although tools exist to aid this process, they are not widely applied for various reasons including non-availability, poor knowledge of the tools, and poor adaptability into the local context. In Uganda, delivery of basic services is devolved to the District Local Governments through the District Health Teams (DHTs). The Community and District Empowerment for Scale-up (CODES) project aims to provide a set of management tools that aid contextualised priority setting, fund allocation, and problem-solving in a systematic way to improve effective coverage and quality of child survival interventions. DESIGN: Although the various tools have previously been used at the national level, the project aims to combine them in an integral way for implementation at the district level. These tools include Lot Quality Assurance Sampling (LQAS) surveys to generate local evidence, Bottleneck analysis and Causal analysis as analytical tools, Continuous Quality Improvement, and Community Dialogues based on Citizen Report Cards and U reports. The tools enable identification of gaps, prioritisation of possible solutions, and allocation of resources accordingly. This paper presents some of the tools used by the project in five districts in Uganda during the proof-of-concept phase of the project. RESULTS: All five districts were trained and participated in LQAS surveys and readily adopted the tools for priority setting and resource allocation. All districts developed health operational work plans, which were based on the evidence and each of the districts implemented more than three of the priority activities which were included in their work plans. CONCLUSIONS: In the five districts, the CODES project demonstrated that DHTs can adopt and integrate these tools in the planning process by systematically identifying gaps and setting priority interventions for child survival.
[Mh] Termos MeSH primário: Serviços de Saúde da Criança/normas
Assistência à Saúde/organização & administração
Amostragem para Garantia da Qualidade de Lotes/métodos
Inovação Organizacional
Poder (Psicologia)
Melhoria de Qualidade
[Mh] Termos MeSH secundário: Criança
Seres Humanos
Alocação de Recursos
Inquéritos e Questionários
Uganda
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160527
[St] Status:MEDLINE
[do] DOI:10.3402/gha.v9.30983


  10 / 92 MEDLINE  
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[PMID]:27167381
[Au] Autor:Jezmir J; Cohen T; Zignol M; Nyakan E; Hedt-Gauthier BL; Gardner A; Kamle L; Injera W; Carter EJ
[Ad] Endereço:Stanford Medical School, Stanford, California, United States of Amercia.
[Ti] Título:Use of Lot Quality Assurance Sampling to Ascertain Levels of Drug Resistant Tuberculosis in Western Kenya.
[So] Source:PLoS One;11(5):e0154142, 2016.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To classify the prevalence of multi-drug resistant tuberculosis (MDR-TB) in two different geographic settings in western Kenya using the Lot Quality Assurance Sampling (LQAS) methodology. DESIGN: The prevalence of drug resistance was classified among treatment-naïve smear positive TB patients in two settings, one rural and one urban. These regions were classified as having high or low prevalence of MDR-TB according to a static, two-way LQAS sampling plan selected to classify high resistance regions at greater than 5% resistance and low resistance regions at less than 1% resistance. RESULTS: This study classified both the urban and rural settings as having low levels of TB drug resistance. Out of the 105 patients screened in each setting, two patients were diagnosed with MDR-TB in the urban setting and one patient was diagnosed with MDR-TB in the rural setting. An additional 27 patients were diagnosed with a variety of mono- and poly- resistant strains. CONCLUSION: Further drug resistance surveillance using LQAS may help identify the levels and geographical distribution of drug resistance in Kenya and may have applications in other countries in the African Region facing similar resource constraints.
[Mh] Termos MeSH primário: Antituberculosos/uso terapêutico
Farmacorresistência Bacteriana Múltipla
Amostragem para Garantia da Qualidade de Lotes/estatística & dados numéricos
Mycobacterium tuberculosis/efeitos dos fármacos
Tuberculose Resistente a Múltiplos Medicamentos/epidemiologia
Tuberculose Pulmonar/epidemiologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Feminino
Seres Humanos
Isoniazida/uso terapêutico
Quênia/epidemiologia
Masculino
Meia-Idade
Mycobacterium tuberculosis/patogenicidade
Mycobacterium tuberculosis/fisiologia
Prevalência
Rifampina/uso terapêutico
População Rural
Tuberculose Resistente a Múltiplos Medicamentos/diagnóstico
Tuberculose Resistente a Múltiplos Medicamentos/tratamento farmacológico
Tuberculose Pulmonar/diagnóstico
Tuberculose Pulmonar/tratamento farmacológico
População Urbana
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antitubercular Agents); V83O1VOZ8L (Isoniazid); VJT6J7R4TR (Rifampin)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170922
[Lr] Data última revisão:
170922
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160512
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0154142



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