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[PMID]:29431355
[Au] Autor:Aydinov GT; Marchenko BI; Sinelnikova YA
[Ti] Título:[The application of complex assessment of the health status of the population in tasks of the improvement of the socio-hygienic monitoring system].
[So] Source:Gig Sanit;95(10):980-5, 2016.
[Is] ISSN:0016-9900
[Cp] País de publicação:Russia (Federation)
[La] Idioma:rus
[Ab] Resumo:Improvement and unification of information and analytical technologies is the one of the priorities, the solution of which will provide the gain in the efficacy and appropriateness of management decisions, developed preventive and wellness measures. In the article there is explained the use of generalized indices of the real risk as criteria for the comprehensive assessment of the health state of the population at the regional and the municipal levels. The proposed criteria make it possible to increase the objectivity of the assessment of the health state in the sociohygienic monitoring system and in the implementation of the special studies of epidemiological type. There are presented results of a comprehensive assessment of the health state of the population in the cities of Rostov region for the ten-year period and according to socio-hygienic monitoring in 2014 year. In terms of twenty of markers characteristics ofpopulation health there were used indices of the total mortality and morbidity rate. There was executed the complex assessment of the cancer prevalence rate in the urban population on nine priority localizations of the malignant tumors, including stomach, colon, rectum, lungs, skin, mammary gland, corpus uteri, ovary and thyroid gland. There were identified territories of high and elevated real risk to health state of the population. There is presented the result of the application of mathematical modeling used for the assessment and prediction of the impact of environmental factors on the complex assessment of the health staty of the population. Results of research were used for the shaping of information and analytical materials in the Rostov region.
[Mh] Termos MeSH primário: Saúde Pública
Medição de Risco
[Mh] Termos MeSH secundário: Monitoramento Epidemiológico
Nível de Saúde
Seres Humanos
Saúde da População/estatística & dados numéricos
Saúde Pública/métodos
Saúde Pública/normas
Melhoria de Qualidade
Medição de Risco/métodos
Medição de Risco/normas
Federação Russa/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180213
[St] Status:MEDLINE


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[PMID]:28449115
[Au] Autor:Rosenberg ES; Hall EW; Sullivan PS; Sanchez TH; Workowski KA; Ward JW; Holtzman D
[Ad] Endereço:Department of Epidemiology, Emory University Rollins School of Public Health.
[Ti] Título:Estimation of State-Level Prevalence of Hepatitis C Virus Infection, US States and District of Columbia, 2010.
[So] Source:Clin Infect Dis;64(11):1573-1581, 2017 Jun 01.
[Is] ISSN:1537-6591
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Background.: Hepatitis C virus (HCV) infection is the most common chronic blood-borne infection in the United States and a leading cause of morbidity and mortality. Previous analyses of the US National Health and Nutrition Examination Survey (NHANES) indicated approximately 3.6 million noninstitutionalized persons with antibody to HCV (anti-HCV). However, state-level prevalence remains less understood and cannot be estimated reliably from NHANES alone. Methods.: We used 3 publicly available government data sources to estimate anti-HCV prevalence in each US state among noninstitutionalized persons aged ≥18 years. A small-area estimation model combined indirect standardization of NHANES-based prevalence with logistic regression modeling of mortality data, listing acute or chronic HCV infection as a cause of death, from the National Vital Statistics System during 1999-2012. Model results were combined with US Census population sizes to estimate total number and prevalence of persons with antibody to HCV in 2010. Results.: National anti-HCV prevalence was 1.67% (95% confidence interval [CI], 1.53-1.90), or 3 911 800 (95% CI, 3 589 400- 4 447 500) adults in 2010. State-specific prevalence ranged from 0.71% (Illinois) to 3.34% (Oklahoma). The West census region had the highest region-specific prevalence (2.14% [95% CI, 1.96-2.48]); 10 of 13 states had rates above the national average. The South had the highest number of persons with anti-HCV (n = 1561600 [95% CI, 1 427 700-1 768 900]). The Midwest had the lowest region-specific prevalence (1.14% [95% CI, 1.04%-1.30%]). Conclusions.: States in the US West and South have been most impacted by hepatitis C. Estimates of HCV infection burden are essential to guide policy and programs to optimally prevent, detect, and cure infection.
[Mh] Termos MeSH primário: Anticorpos Anti-Hepatite C/sangue
Hepatite C Crônica/epidemiologia
Hepatite C/epidemiologia
[Mh] Termos MeSH secundário: Adulto
Idoso
District of Columbia/epidemiologia
Monitoramento Epidemiológico
Feminino
Hepacivirus/genética
Hepacivirus/imunologia
Hepacivirus/isolamento & purificação
Hepatite C/imunologia
Hepatite C/mortalidade
Hepatite C/virologia
Hepatite C Crônica/virologia
Seres Humanos
Modelos Logísticos
Masculino
Meia-Idade
Inquéritos Nutricionais
Prevalência
RNA Viral/sangue
Fatores de Risco
Estados Unidos/epidemiologia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Hepatitis C Antibodies); 0 (RNA, Viral)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170428
[St] Status:MEDLINE
[do] DOI:10.1093/cid/cix202


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[PMID]:29231629
[Au] Autor:Walberg M; Radtke A
[Ti] Título:Infections in the healthcare service - time for a smart approach.
[Ti] Título:Infeksjoner i helsetjenesten ­ på tide å arbeide smart..
[So] Source:Tidsskr Nor Laegeforen;137(23-24), 2017 12 12.
[Is] ISSN:0807-7096
[Cp] País de publicação:Norway
[La] Idioma:eng; nor
[Mh] Termos MeSH primário: Infecção Hospitalar/epidemiologia
Monitoramento Epidemiológico
Controle de Infecções/normas
[Mh] Termos MeSH secundário: Infecção Hospitalar/prevenção & controle
Seres Humanos
Notificação Compulsória
Noruega/epidemiologia
Prevalência
Garantia da Qualidade dos Cuidados de Saúde
Sistema de Registros
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180306
[Lr] Data última revisão:
180306
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171213
[St] Status:MEDLINE
[do] DOI:10.4045/tidsskr.17.0904


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[PMID]:29424211
[Au] Autor:Rakhmanin YA; Zhuravlev PV; Aleshnya VV; Panasovets OV
[Ti] Título:[Application of the new culture medium for the isolation of Salmonella from water bodies to assess the epidemic safety of water use. Gigiena i Sanitaria (Hygiene and Sanitation, Russian)].
[So] Source:Gig Sanit;95(5):483-90, 2016.
[Is] ISSN:0016-9900
[Cp] País de publicação:Russia (Federation)
[La] Idioma:rus
[Ab] Resumo:There was developed a liquid storage medium for the isolation of bacteria of genus Salmonella from water bodies (The culture medium for the accumulation of Salmonella, ready to use, "RNS"), providing the accumulation of Salmonella from different serogroups, inhibiting the growth of accompanying microflora, allowing to obtain objective information about the extent of bacterial contamination of water bodies. Medium is by nature of a solution for microbiological purposes which is produced by mixing the components with consequentfiltration and sterilization. In an experimental way there were chosen optimal ratios of the nutrient medium ingredients: extract offodder yeast in an amount of 4.55.0 g/l, sodium hydroxide - to 1.3-1.4 g/l, potassium phosphate - 8.6-8.8 g/l. The medium is a sterile, clear liquid, green in color, medium pH is 6.4 to 6.8, amine nitrogen - from 0.05 to 0.1%. Designed medium for accumulation is sensitivity, it ensures the growth of the test strains of salmonella at seeding of single cells in that favorably differs from similar media used in public health practice at the present time. The smallest time for the accumulation of biomass of Salmonella accounts of 6 hours, the optimal time is 24 hours. Incubation of crops is produced at 37 °C. Cultures of Salmonella at seeding in the developed medium retain their biological properties. Developed medium in terms of sensitivity is superior to magnesian and selenite media.
[Mh] Termos MeSH primário: Técnicas Bacteriológicas
Meios de Cultura/farmacologia
Salmonella/isolamento & purificação
[Mh] Termos MeSH secundário: Técnicas Bacteriológicas/instrumentação
Técnicas Bacteriológicas/métodos
Monitoramento Epidemiológico
Seres Humanos
Reprodutibilidade dos Testes
Microbiologia da Água
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Culture Media)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180301
[Lr] Data última revisão:
180301
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180210
[St] Status:MEDLINE


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[PMID]:29385161
[Au] Autor:Zheng H; Woodall WH; Carlson AL; DeLisle S
[Ad] Endereço:Department of Medicine, Veterans Affairs Maryland Health Care System, Baltimore, MD, United States of America.
[Ti] Título:Can long-term historical data from electronic medical records improve surveillance for epidemics of acute respiratory infections? A systematic evaluation.
[So] Source:PLoS One;13(1):e0191324, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: As the deployment of electronic medical records (EMR) expands, so is the availability of long-term datasets that could serve to enhance public health surveillance. We hypothesized that EMR-based surveillance systems that incorporate seasonality and other long-term trends would discover outbreaks of acute respiratory infections (ARI) sooner than systems that only consider the recent past. METHODS: We simulated surveillance systems aimed at discovering modeled influenza outbreaks injected into backgrounds of patients with ARI. Backgrounds of daily case counts were either synthesized or obtained by applying one of three previously validated ARI case-detection algorithms to authentic EMR entries. From the time of outbreak injection, detection statistics were applied daily on paired background+injection and background-only time series. The relationship between the detection delay (the time from injection to the first alarm uniquely found in the background+injection data) and the false-alarm rate (FAR) was determined by systematically varying the statistical alarm threshold. We compared this relationship for outbreak detection methods that utilized either 7 days (early aberrancy reporting system (EARS)) or 2-4 years of past data (seasonal autoregressive integrated moving average (SARIMA) time series modeling). RESULTS: In otherwise identical surveillance systems, SARIMA detected epidemics sooner than EARS at any FAR below 10%. The algorithms used to detect single ARI cases impacted both the feasibility and marginal benefits of SARIMA modeling. Under plausible real-world conditions, SARIMA could reduce detection delay by 5-16 days. It also was more sensitive at detecting the summer wave of the 2009 influenza pandemic. CONCLUSION: Time series modeling of long-term historical EMR data can reduce the time it takes to discover epidemics of ARI. Realistic surveillance simulations may prove invaluable to optimize system design and tuning.
[Mh] Termos MeSH primário: Registros Eletrônicos de Saúde
Monitoramento Epidemiológico
Infecções Respiratórias/epidemiologia
[Mh] Termos MeSH secundário: Doença Aguda/epidemiologia
Seres Humanos
Influenza Humana/epidemiologia
Pandemias
[Pt] Tipo de publicação:EVALUATION STUDIES; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180226
[Lr] Data última revisão:
180226
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180201
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0191324


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[PMID]:29298018
[Au] Autor:Kolesnikov SI; Savilov ED; Savchenkov MF; Leshchenko YA; Malov IV; Anganova EV; Astaf'ev VA; Shugaeva SN
[Ti] Título:Sanitary-Epidemiological Status of Siberian Population (Medico-Demographical and Epidemiological Characteristics).
[So] Source:Vestn Ross Akad Med Nauk;71(6):472-81, 2016.
[Is] ISSN:0869-6047
[Cp] País de publicação:Russia (Federation)
[La] Idioma:eng
[Ab] Resumo:Review on the problem of sanitary-epidemiological welfare of the population in the Siberian Federal District (SFD) was conducted based on literature data and authors own research in the period of 2002−2014. Authors provided broad information on the health and demographic and epidemiological characteristics of SFD population. SFD in comparison with other regions of the Russian Federation overcomes one of the most adverse situations including mortality rates from external causes. SFD population's infectious and somatic morbidity rates were analyzed. Analysis demonstrated that the situation relating to priority epidemiologically and socially important infections (HIV-infection, parenteral viral hepatitis, tuberculosis etc.) on the territory of the SFD remains tense. Authors provided information on the increase in the level of the actual for Siberian regions natural-foci tick-borne infections. Detailed analysis for the environment anthropogenic pollution impact for the epidemic, infectious and vaccine induced processes. Authors suggest that anthropogenic (biological) environmental pollution is one of the most important factors influencing the epidemiological welfare of the Siberian population. A new strategic direction in epidemiological research associated with the problem of comorbid diseases is planned.
[Mh] Termos MeSH primário: Demografia
Monitoramento Epidemiológico
Saúde Pública
[Mh] Termos MeSH secundário: Seres Humanos
Saúde Pública/métodos
Saúde Pública/estatística & dados numéricos
Sibéria/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180220
[Lr] Data última revisão:
180220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180104
[St] Status:MEDLINE


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[PMID]:29204739
[Au] Autor:Kim HK; Kim HJ; Noh JY; Van Phan L; Kim JH; Song D; Na W; Kang A; Nguyen TL; Shin JH; Jeong DG; Yoon SW
[Ad] Endereço:Infectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea.
[Ti] Título:Serological evidence of H5-subtype influenza A virus infection in indigenous avian and mammalian species in Korea.
[So] Source:Arch Virol;163(3):649-657, 2018 Mar.
[Is] ISSN:1432-8798
[Cp] País de publicação:Austria
[La] Idioma:eng
[Ab] Resumo:In Korea, H5-subtype highly pathogenic avian influenza (HPAI) has caused huge economic losses in poultry farms through outbreaks of H5N1 since 2003, H5N8 since 2013 and H5N6 since 2016. Although it was reported that long-distance migratory birds may play a major role in the global spread of avian influenza viruses (AIVs), transmission from such birds to poultry has not been confirmed. Intermediate hosts in the wild also may be a potential factor in viral transmission. Therefore, a total of 367 serum samples from wild animals were collected near major migratory bird habitats from 2011 to 2016 and tested by AIV-specific blocking ELISA and hemagglutination inhibition (HI) test. Two mammalian and eight avian species were seropositive according to the ELISA test. Among these, two mammalian (Hydropotes inermis and Prionailurus bengalensis) and three avian (Aegypius monachus, Cygnus cygnus, and Bubo bubo) species showed high HI titres (> 1,280) against one or two H5-subtype AIVs. As H. inermis (water deer), P. bengalensis (leopard cat), and B. bubo (Eurasian eagle owl) are indigenous animals in Korea, evidence of H5-subtype AIV in these animals implies that continuous monitoring of indigenous animals should be followed to understand interspecies transmission ecology of H5-subtype influenza viruses.
[Mh] Termos MeSH primário: Anticorpos Antivirais/sangue
Vírus da Influenza A Subtipo H5N1/isolamento & purificação
Vírus da Influenza A Subtipo H5N2/isolamento & purificação
Vírus da Influenza A Subtipo H5N8/isolamento & purificação
Influenza Aviária/epidemiologia
Infecções por Orthomyxoviridae/epidemiologia
[Mh] Termos MeSH secundário: Animais
Animais Selvagens/virologia
Aves/virologia
Cervos/virologia
Monitoramento Epidemiológico
Felidae/virologia
Testes de Inibição da Hemaglutinação
Vírus da Influenza A Subtipo H5N1/classificação
Vírus da Influenza A Subtipo H5N1/imunologia
Vírus da Influenza A Subtipo H5N2/classificação
Vírus da Influenza A Subtipo H5N2/imunologia
Vírus da Influenza A Subtipo H5N8/classificação
Vírus da Influenza A Subtipo H5N8/imunologia
Influenza Aviária/sangue
Influenza Aviária/imunologia
Influenza Aviária/virologia
Infecções por Orthomyxoviridae/sangue
Infecções por Orthomyxoviridae/imunologia
Infecções por Orthomyxoviridae/virologia
Filogenia
República da Coreia/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antibodies, Viral)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180220
[Lr] Data última revisão:
180220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171206
[St] Status:MEDLINE
[do] DOI:10.1007/s00705-017-3655-z


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[PMID]:29304039
[Au] Autor:Raftery P; Condell O; Wasunna C; Kpaka J; Zwizwai R; Nuha M; Fallah M; Freeman M; Harris V; Miller M; Baller A; Massaquoi M; Katawera V; Saindon J; Bemah P; Hamblion E; Castle E; Williams D; Gasasira A; Nyenswah T
[Ad] Endereço:EVD Response Team, World Health Organization, Monrovia, Montserrado, Liberia.
[Ti] Título:Establishing Ebola Virus Disease (EVD) diagnostics using GeneXpert technology at a mobile laboratory in Liberia: Impact on outbreak response, case management and laboratory systems strengthening.
[So] Source:PLoS Negl Trop Dis;12(1):e0006135, 2018 01.
[Is] ISSN:1935-2735
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The 2014-16 Ebola Virus Disease (EVD) outbreak in West Africa highlighted the necessity for readily available, accurate and rapid diagnostics. The magnitude of the outbreak and the re-emergence of clusters of EVD cases following the declaration of interrupted transmission in Liberia, reinforced the need for sustained diagnostics to support surveillance and emergency preparedness. We describe implementation of the Xpert Ebola Assay, a rapid molecular diagnostic test run on the GeneXpert platform, at a mobile laboratory in Liberia and the subsequent impact on EVD outbreak response, case management and laboratory system strengthening. During the period of operation, site coordination, management and operational capacity was supported through a successful collaboration between Ministry of Health (MoH), World Health Organization (WHO) and international partners. A team of Liberian laboratory technicians were trained to conduct EVD diagnostics and the laboratory had capacity to test 64-100 blood specimens per day. Establishment of the laboratory significantly increased the daily testing capacity for EVD in Liberia, from 180 to 250 specimens at a time when the effectiveness of the surveillance system was threatened by insufficient diagnostic capacity. During the 18 months of operation, the laboratory tested a total of 9,063 blood specimens, including 21 EVD positives from six confirmed cases during two outbreaks. Following clearance of the significant backlog of untested EVD specimens in November 2015, a new cluster of EVD cases was detected at the laboratory. Collaboration between surveillance and laboratory coordination teams during this and a later outbreak in March 2016, facilitated timely and targeted response interventions. Specimens taken from cases during both outbreaks were analysed at the laboratory with results informing clinical management of patients and discharge decisions. The GeneXpert platform is easy to use, has relatively low running costs and can be integrated into other national diagnostic algorithms. The technology has on average a 2-hour sample-to-result time and allows for single specimen testing to overcome potential delays of batching. This model of a mobile laboratory equipped with Xpert Ebola test, staffed by local laboratory technicians, could serve to strengthen outbreak preparedness and response for future outbreaks of EVD in Liberia and the region.
[Mh] Termos MeSH primário: Surtos de Doenças/prevenção & controle
Monitoramento Epidemiológico
Doença pelo Vírus Ebola/diagnóstico
Doença pelo Vírus Ebola/epidemiologia
Unidades Móveis de Saúde
[Mh] Termos MeSH secundário: Administração de Caso
Ebolavirus/isolamento & purificação
Doença pelo Vírus Ebola/virologia
Seres Humanos
Libéria/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180210
[Lr] Data última revisão:
180210
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180106
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pntd.0006135


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[PMID]:29326249
[Au] Autor:Roberts L
[Ti] Título:In Pakistan, surveillance for polio reveals a paradox.
[So] Source:Science;359(6372):142-143, 2018 Jan 12.
[Is] ISSN:1095-9203
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Monitoramento Epidemiológico
Poliomielite/epidemiologia
Poliovirus/isolamento & purificação
Esgotos/virologia
[Mh] Termos MeSH secundário: Área Programática (Saúde)
Criança
Pré-Escolar
Erradicação de Doenças
Seres Humanos
Programas de Imunização
Lactente
Paquistão/epidemiologia
Paralisia
Poliomielite/imunologia
Poliomielite/prevenção & controle
Poliovirus/imunologia
Poliovirus/fisiologia
Vacinas contra Poliovirus/administração & dosagem
[Pt] Tipo de publicação:NEWS
[Nm] Nome de substância:
0 (Poliovirus Vaccines); 0 (Sewage)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180207
[Lr] Data última revisão:
180207
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180113
[St] Status:MEDLINE
[do] DOI:10.1126/science.359.6372.142


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[PMID]:29297852
[Au] Autor:Korsun N; Angelova S; Trifonova I; Tzotcheva I; Mileva S; Voleva S; Georgieva I; Perenovska P
[Ad] Endereço:1​National Reference Laboratory "Influenza and ARD", National Centre of Infectious and Parasitic Diseases, 44A Stoletov Blvd, 1233 Sofia, Bulgaria.
[Ti] Título:Predominance of influenza A(H3N2) viruses during the 2016/2017 season in Bulgaria.
[So] Source:J Med Microbiol;67(2):228-239, 2018 Feb.
[Is] ISSN:1473-5644
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:PURPOSE: Influenza viruses are characterised by high variability, which makes them able to cause annual epidemics. The aim of this study is to determine the antigenic and genetic characteristics of influenza viruses circulating in Bulgaria during the 2016/2017 season. METHODOLOGY: The detection and typing/subtyping of influenza viruses were performed using real time RT-PCR. Results of antigenic characterisation, phylogenetic and amino acid sequence analyses of representative influenza strains are presented herein. RESULTS: The 2016/2017 season was characterised by an early start, an exclusive dominance of A(H3N2) viruses accounting for 93 % of total influenza virus detections, and a low circulation of A(H1N1)pdm09 (4.2 %) and type B (2.5 %) viruses. The analysed A(H3N2) viruses belonged to subclades 3C.2a (52 %) and 3C.2a1 (48 %); all studied A(H1N1)pdm09 and B/Victoria-lineage viruses belonged to subclades 6B.1 and 1A, respectively. The amino acid sequence analysis of 56 A(H3N2) isolates revealed the presence of substitutions in 18 positions in haemagglutinin (HA) as compared to the A/Hong Kong/4801/2014 vaccine virus, seven of which occurred in four antigenic sites, together with changes in 23 positions in neuraminidase (NA), and a number of substitutions in internal proteins PB2, PB1, PB1-F2, PA, NP and NS1. Despite the many amino acid substitutions, A(H3N2) viruses remained antigenically similar to the vaccine strain. Substitutions in HA and NA sequences of A(H1N1)pdm09 and B/Victoria-lineage strains were also identified, including in antigenic sites. CONCLUSION: The results of this study confirm the genetic variability of circulating influenza viruses, particularly A(H3N2), and the need for continued antigenic and molecular surveillance.
[Mh] Termos MeSH primário: Vírus da Influenza A Subtipo H3N2/isolamento & purificação
Influenza Humana/epidemiologia
Influenza Humana/virologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Substituição de Aminoácidos
Bulgária/epidemiologia
Criança
Pré-Escolar
Monitoramento Epidemiológico
Evolução Molecular
Feminino
Variação Genética
Genoma Viral
Glicoproteínas de Hemaglutininação de Vírus da Influenza/genética
Seres Humanos
Vírus da Influenza A Subtipo H1N1/classificação
Vírus da Influenza A Subtipo H1N1/genética
Vírus da Influenza A Subtipo H1N1/isolamento & purificação
Vírus da Influenza A Subtipo H3N2/classificação
Vírus da Influenza A Subtipo H3N2/genética
Vírus da Influenza A Subtipo H3N2/imunologia
Vírus da Influenza B/classificação
Vírus da Influenza B/genética
Vírus da Influenza B/isolamento & purificação
Masculino
Neuraminidase/genética
Filogenia
RNA Viral/genética
Reação em Cadeia da Polimerase em Tempo Real
Estações do Ano
Análise de Sequência de DNA
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Hemagglutinin Glycoproteins, Influenza Virus); 0 (RNA, Viral); EC 3.2.1.18 (Neuraminidase)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180206
[Lr] Data última revisão:
180206
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180104
[St] Status:MEDLINE
[do] DOI:10.1099/jmm.0.000668



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