Base de dados : MEDLINE
Pesquisa : E05.318.740.994.250 [Categoria DeCS]
Referências encontradas : 927 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 93 ir para página                         

  1 / 927 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28359175
[Au] Autor:Eads DA; Hoogland JL
[Ad] Endereço:Department of Biology, Colorado State University, Fort Collins, Colorado 80523. Correspondence should be sent to David A. Eads at: daeads@colostate.edu.
[Ti] Título:Precipitation, Climate Change, and Parasitism of Prairie Dogs by Fleas that Transmit Plague.
[So] Source:J Parasitol;103(4):309-319, 2017 Aug.
[Is] ISSN:1937-2345
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Fleas (Insecta: Siphonaptera) are hematophagous ectoparasites that can reduce the fitness of vertebrate hosts. Laboratory populations of fleas decline under dry conditions, implying that populations of fleas will also decline when precipitation is scarce under natural conditions. If precipitation and hence vegetative production are reduced, however, then herbivorous hosts might suffer declines in body condition and have weakened defenses against fleas, so that fleas will increase in abundance. We tested these competing hypotheses using information from 23 yr of research on 3 species of colonial prairie dogs in the western United States: Gunnison's prairie dog (Cynomys gunnisoni, 1989-1994), Utah prairie dog (Cynomys parvidens, 1996-2005), and white-tailed prairie dog (Cynomys leucurus, 2006-2012). For all 3 species, flea-counts per individual varied inversely with the number of days in the prior growing season with >10 mm of precipitation, an index of the number of precipitation events that might have caused a substantial, prolonged increase in soil moisture and vegetative production. Flea-counts per Utah prairie dog also varied inversely with cumulative precipitation of the prior growing season. Furthermore, flea-counts per Gunnison's and white-tailed prairie dog varied inversely with cumulative precipitation of the just-completed January and February. These results complement research on black-tailed prairie dog (Cynomys ludovicianus) and might have important ramifications for plague, a bacterial disease transmitted by fleas that devastates populations of prairie dogs. In particular, our results might help to explain why, at some colonies, epizootics of plague, which can kill >95% of prairie dogs, are more likely to occur during or shortly after periods of reduced precipitation. Climate change is projected to increase the frequency of droughts in the grasslands of western North America. If so, then climate change might affect the occurrence of plague epizootics among prairie dogs and other mammalian species that associate with them.
[Mh] Termos MeSH primário: Infestações por Pulgas/veterinária
Doenças dos Roedores/parasitologia
Sciuridae/parasitologia
[Mh] Termos MeSH secundário: Distribuição por Idade
Animais
Arizona/epidemiologia
Distribuição Binomial
Mudança Climática
Colorado/epidemiologia
Feminino
Infestações por Pulgas/epidemiologia
Infestações por Pulgas/parasitologia
Modelos Lineares
Masculino
Peste/epidemiologia
Peste/transmissão
Peste/veterinária
Chuvas
Doenças dos Roedores/epidemiologia
Estações do Ano
Distribuição por Sexo
Sifonápteros/classificação
Sifonápteros/microbiologia
Utah/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170818
[Lr] Data última revisão:
170818
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170401
[St] Status:MEDLINE
[do] DOI:10.1645/16-195


  2 / 927 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28257479
[Au] Autor:Aslam M; Arif OH; Jun CH
[Ad] Endereço:Department of Statistics, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia.
[Ti] Título:An attribute control chart for a Weibull distribution under accelerated hybrid censoring.
[So] Source:PLoS One;12(3):e0173406, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:In this article, an attribute control chart has been proposed using the accelerated hybrid censoring logic for the monitoring of defective items whose life follows a Weibull distribution. The product can be tested by introducing the acceleration factor based on different pressurized conditions such as stress, load, strain, temperature, etc. The control limits are derived based on the binomial distribution, but the fraction defective is expressed only through the shape parameter, the acceleration factor and the test duration constant. Tables of the average run lengths have been generated for different process parameters to assess the performance of the proposed control chart. Simulation studies have been performed for the practical use, where the proposed chart is compared with the Shewhart np chart for demonstration of the detection power of a process shift.
[Mh] Termos MeSH primário: Algoritmos
Modelos Teóricos
Semicondutores
[Mh] Termos MeSH secundário: Distribuição Binomial
Controle de Qualidade
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170829
[Lr] Data última revisão:
170829
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170304
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0173406


  3 / 927 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28025767
[Au] Autor:An R; Yang Y; Li K
[Ad] Endereço:Department of Kinesiology and Community Health, College of Applied Health Sciences, University of Illinois at Urbana-Champaign, 1206 South 4th Street, Champaign, IL, 61820, USA. ran5@illinois.edu.
[Ti] Título:Residential Neighborhood Amenities and Physical Activity Among U.S. Children with Special Health Care Needs.
[So] Source:Matern Child Health J;21(5):1026-1036, 2017 May.
[Is] ISSN:1573-6628
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Objectives Children with special health care needs (SHCN) have or are at elevated risk for chronic physical, developmental, behavioral or emotional conditions and therefore require specialized health care services. This study examines the relationship between residential neighborhood amenities and physical activity among U.S. children with SHCN. Methods A nationally representative sample of 113,767 children aged 6-17 years was taken from National Survey of Children's Health (NSCH) 2007-2008 and 2011-2012. Residential neighborhood amenities were defined by parent-reported presence or absence of sidewalks, parks/playgrounds, and recreation center. Physical activity was measured by parent-reported number of physically active days (0-7), defined as 20 min or longer during the past week. Negative binomial regressions were performed to estimate the associations between residential neighborhood amenities and physical activity among U.S. children with and without SHCN, adjusting for various neighborhood (detracting condition and safety) and individual characteristics and NSCH sampling design. Results Approximately 23% of young children aged 6-11 years and adolescents aged 12-17 years had SHCN. Number of weekly physically active days was both 4.8 among young children with and without SHCN, and 3.7 and 4.1 among adolescents with and without SHCN, respectively. Among young children with SHCN, neighborhood availability of a recreation center was associated with increased weekly physically active days by 0.23; whereas among young children without SHCN, number of weekly physically active days was not associated with the availability of any amenity. Among adolescents with SHCN, neighborhood availability of parks/playgrounds was associated with increased weekly physically active days by 0.33, whereas neighborhood availability of sidewalks was associated with reduced weekly physically active days by 0.21. Conversely, among adolescents without SHCN, neighborhood availability of a recreation center was associated with increased weekly physically active days by 0.22. Conclusions for Practice Vulnerable health status and high dependence on health care may prevent children with SHCN from being physically active. Provision of adequate amenities in residential neighborhoods could be essential in promoting physical activity and preventing obesity among children/adolescents with SHCN.
[Mh] Termos MeSH primário: Crianças com Deficiência/estatística & dados numéricos
Planejamento Ambiental/normas
Exercício/psicologia
Parques Recreativos/estatística & dados numéricos
Distribuição Espacial da População/estatística & dados numéricos
[Mh] Termos MeSH secundário: Adolescente
Distribuição Binomial
Centers for Disease Control and Prevention (U.S.)/organização & administração
Criança
Estudos Transversais
Feminino
Acesso aos Serviços de Saúde/estatística & dados numéricos
Seres Humanos
Masculino
Inquéritos e Questionários
Estados Unidos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:171030
[Lr] Data última revisão:
171030
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161228
[St] Status:MEDLINE
[do] DOI:10.1007/s10995-016-2198-3


  4 / 927 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27669702
[Au] Autor:Raidvee A; Lember J; Allik J
[Ad] Endereço:Department of Psychology, University of Tartu, Näituse 2, Tartu, 50409, Estonia. aire.raidvee@ut.ee.
[Ti] Título:Discrimination of numerical proportions: A comparison of binomial and Gaussian models.
[So] Source:Atten Percept Psychophys;79(1):267-282, 2017 Jan.
[Is] ISSN:1943-393X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Observers discriminated the numerical proportion of two sets of elements (N = 9, 13, 33, and 65) that differed either by color or orientation. According to the standard Thurstonian approach, the accuracy of proportion discrimination is determined by irreducible noise in the nervous system that stochastically transforms the number of presented visual elements onto a continuum of psychological states representing numerosity. As an alternative to this customary approach, we propose a Thurstonian-binomial model, which assumes discrete perceptual states, each of which is associated with a certain visual element. It is shown that the probability ß with which each visual element can be noticed and registered by the perceptual system can explain data of numerical proportion discrimination at least as well as the continuous Thurstonian-Gaussian model, and better, if the greater parsimony of the Thurstonian-binomial model is taken into account using AIC model selection. We conclude that Gaussian and binomial models represent two different fundamental principles-internal noise vs. using only a fraction of available information-which are both plausible descriptions of visual perception.
[Mh] Termos MeSH primário: Atenção/fisiologia
Distribuição Binomial
Conceitos Matemáticos
Modelos Teóricos
Distribuição Normal
Percepção Visual/fisiologia
[Mh] Termos MeSH secundário: Adulto
Discriminação (Psicologia)/fisiologia
Feminino
Seres Humanos
Adulto Jovem
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171109
[Lr] Data última revisão:
171109
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160928
[St] Status:MEDLINE
[do] DOI:10.3758/s13414-016-1188-2


  5 / 927 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27999279
[Au] Autor:Liu Y; Astell-Burt T; Liu J; Yin P; Feng X; You J; Page A; Zhou M; Wang L
[Ad] Endereço:National Center for Chronic and Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, China. liuyunning0723@163.com.
[Ti] Título:Spatiotemporal Variations in Lung Cancer Mortality in China between 2006 and 2012: A Multilevel Analysis.
[So] Source:Int J Environ Res Public Health;13(12), 2016 Dec 16.
[Is] ISSN:1660-4601
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:We investigated temporal trends and geographical variations in lung cancer mortality in China from 2006 to 2012. Lung cancer mortality counts for people aged over 40 years were extracted from the China Mortality Surveillance System for 161 disease surveillance points. Negative binomial regression was used to investigate potential spatiotemporal variation and correlations with age, gender, urbanization, and region. Lung cancer mortality increased in China over the study period from 78.77 to 85.63 (1/100,000), with higher mortality rates evident in men compared to women. Median rate ratios (MRRs) indicated important geographical variation in lung cancer mortality between provinces (MRR = 1.622) and counties/districts (MRR = 1.447). On average, lung cancer mortality increased over time and was positively associated with county-level urbanization (relative risk (RR) = 1.15). Lung cancer mortality seemed to decrease in urban and increase in rural areas. Compared to the northwest, mortality was higher in the north (RR = 1.98), east (RR = 1.87), central (RR = 1.87), and northeast (RR = 2.44). Regional differences and county-level urbanization accounted for 49.4% and 8.7% of provincial and county variation, respectively. Reductions in lung cancer mortality in urban areas may reflect improvements in access to preventive healthcare and treatment services. Rising mortality in rural areas may reflect a clustering of risk factors associated with rapid urbanization.
[Mh] Termos MeSH primário: Neoplasias Pulmonares/mortalidade
[Mh] Termos MeSH secundário: Idoso
Distribuição Binomial
China/epidemiologia
Demografia
Feminino
Seres Humanos
Neoplasias Pulmonares/epidemiologia
Masculino
Meia-Idade
Análise Multinível
Vigilância da População
Serviços Preventivos de Saúde
Análise de Regressão
Fatores de Risco
Análise Espaço-Temporal
População Urbana
Urbanização
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170726
[Lr] Data última revisão:
170726
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161222
[St] Status:MEDLINE


  6 / 927 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
[PMID]:27809859
[Au] Autor:Bell N; Repáraz L; Fry WR; Smith RS; Luis A
[Ad] Endereço:College of Nursing, University of South Carolina, 1601 Greene Street, Columbia, SC, 29208, USA. nathaniel@sc.edu.
[Ti] Título:Variation in type and frequency of diagnostic imaging during trauma care across multiple time points by patient insurance type.
[So] Source:BMC Med Imaging;16(1):61, 2016 Nov 03.
[Is] ISSN:1471-2342
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Research has shown that uninsured patients receive fewer radiographic studies during trauma care, but less is known as to whether differences in care are present among other insurance groups or across different time points during hospitalization. Our objective was to examine the number of radiographic studies administered to a cohort of trauma patients over the entire hospital stay as well as during the first 24-hours of care. METHODS: Patient data were obtained from an American College of Surgeons (ACS) verified Level I Trauma Center between January 1, 2011 and December 31, 2012. We used negative binomial regression to construct relative risk (RR) ratios for type and frequency of radiographic imaging received among persons with Medicare, Medicaid, no insurance, or government insurance plans in reference to those with commercial indemnity plans. The analysis was adjusted for patient age, sex, race/ethnicity, injury severity score, injury mechanism, comorbidities, complications, hospital length of stay, and Intensive Care Unit (ICU) admission. RESULTS: A total of 3621 records from surviving patients age > =18 years were assessed. After adjustment for potential confounders, the expected number of radiographic studies decreased by 15 % among Medicare recipients (RR 0.85, 95 % CI 0.78-0.93), 11 % among Medicaid recipients (0.89, 0.81-0.99), 10 % among the uninsured (0.90, 0.85-0.96) and 19 % among government insurance groups (0.81, 0.72-0.90), compared with the reference group. This disparity was observed during the first 24-hours of care among patients with Medicare (0.78, 0.71-0.86) and government insurance plans (0.83, 0.74-0.94). Overall, there were no differences in the number of radiographic studies among the uninsured or among Medicaid patients during the first 24-hours of care compared with the reference group, but differences were observed among the uninsured in a sub-analysis of severely injured patients (ISS > 15). CONCLUSIONS: Both uninsured and insured patients treated at a not-for-profit verified Level I Trauma Center receive fewer radiographic studies than patients with commercial indemnity plans, even after adjusting for clinical and demographic confounders. There is less disparity in care during the first 24-hours, which suggests that patient pathology is the determining factor for radiographic evaluation during the acute care phase. Results from this study offer initial evidence of disparity in diagnostic imaging across multiple insurance groups over different periods of trauma care.
[Mh] Termos MeSH primário: Diagnóstico por Imagem/métodos
Disparidades em Assistência à Saúde
Seguro Saúde/classificação
[Mh] Termos MeSH secundário: Adulto
Idoso
Idoso de 80 Anos ou mais
Distribuição Binomial
Bases de Dados Factuais
Diagnóstico por Imagem/estatística & dados numéricos
Feminino
Disparidades em Assistência à Saúde/etnologia
Disparidades em Assistência à Saúde/estatística & dados numéricos
Hospitalização
Seres Humanos
Masculino
Meia-Idade
Estudos Retrospectivos
Índice de Gravidade de Doença
Centros de Traumatologia
Estados Unidos
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171017
[Lr] Data última revisão:
171017
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161105
[St] Status:MEDLINE


  7 / 927 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
[PMID]:27740539
[Au] Autor:DeFlorio-Barker S; Wade TJ; Turyk M; Dorevitch S
[Ad] Endereço:Division of Environmental and Occupational Health Sciences, School of Public Health, University of Illinois, Chicago, Illinois, USA E-mail: sdeflor2@uic.edu.
[Ti] Título:Water recreation and illness severity.
[So] Source:J Water Health;14(5):713-726, 2016 Oct.
[Is] ISSN:1477-8920
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The health endpoint of prior studies of water recreation has been the occurrence of gastrointestinal (GI) illness. This dichotomous measure fails to take into account the range of symptom severity among those with GI illness, and those who develop GI symptoms but who do not satisfy the definition of GI illness. Data from two US cohort studies were used to assess use of ordinal and semi-continuous measures of GI symptoms, such as duration of GI symptoms and responses to those symptoms such as medication use, interference with daily activities, and utilization of healthcare service. Zero-inflated negative binomial and logistic regression models were used to assess associations between severity and either the degree of water exposure or water quality. Among 37,404 water recreators without baseline GI symptoms, we observed individuals with relatively low severity satisfying the case definition of GI illness, while others with high severity not satisfying that definition. Severity metrics were associated with water exposure. The dichotomous GI illness outcome could be improved by considering symptom severity in future studies. Modeling ordinal and semi-continuous outcomes may improve our understanding of determinants of the burden of illness rather than simply the number of cases of illness attributable to environmental exposures.
[Mh] Termos MeSH primário: Efeitos Psicossociais da Doença
Exposição Ambiental
Gastroenteropatias/epidemiologia
Microbiologia da Água
Qualidade da Água
[Mh] Termos MeSH secundário: Distribuição Binomial
Estudos de Coortes
Gastroenteropatias/microbiologia
Gastroenteropatias/parasitologia
Seres Humanos
Modelos Logísticos
Recreação
Medição de Risco
Estados Unidos/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170117
[Lr] Data última revisão:
170117
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161015
[St] Status:MEDLINE


  8 / 927 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
PubMed Central Texto completo
Texto completo
[PMID]:27639558
[Au] Autor:Zhang C; Cai H; Huang J; Song Y
[Ad] Endereço:School of Computer Science & Engineering, South China University of Technology, Guangzhou, 510006, China.
[Ti] Título:nbCNV: a multi-constrained optimization model for discovering copy number variants in single-cell sequencing data.
[So] Source:BMC Bioinformatics;17:384, 2016 Sep 17.
[Is] ISSN:1471-2105
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Variations in DNA copy number have an important contribution to the development of several diseases, including autism, schizophrenia and cancer. Single-cell sequencing technology allows the dissection of genomic heterogeneity at the single-cell level, thereby providing important evolutionary information about cancer cells. In contrast to traditional bulk sequencing, single-cell sequencing requires the amplification of the whole genome of a single cell to accumulate enough samples for sequencing. However, the amplification process inevitably introduces amplification bias, resulting in an over-dispersing portion of the sequencing data. Recent study has manifested that the over-dispersed portion of the single-cell sequencing data could be well modelled by negative binomial distributions. RESULTS: We developed a read-depth based method, nbCNV to detect the copy number variants (CNVs). The nbCNV method uses two constraints-sparsity and smoothness to fit the CNV patterns under the assumption that the read signals are negatively binomially distributed. The problem of CNV detection was formulated as a quadratic optimization problem, and was solved by an efficient numerical solution based on the classical alternating direction minimization method. CONCLUSIONS: Extensive experiments to compare nbCNV with existing benchmark models were conducted on both simulated data and empirical single-cell sequencing data. The results of those experiments demonstrate that nbCNV achieves superior performance and high robustness for the detection of CNVs in single-cell sequencing data.
[Mh] Termos MeSH primário: Variações do Número de Cópias de DNA/genética
Sequenciamento de Nucleotídeos em Larga Escala/métodos
Análise de Célula Única/métodos
Software
[Mh] Termos MeSH secundário: Distribuição Binomial
Análise por Conglomerados
Simulação por Computador
Seres Humanos
Análise de Sequência de DNA
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170804
[Lr] Data última revisão:
170804
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160919
[St] Status:MEDLINE
[do] DOI:10.1186/s12859-016-1239-7


  9 / 927 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27623864
[Au] Autor:Dong K; Zhao H; Tong T; Wan X
[Ad] Endereço:Department of Mathematics, Hong Kong Baptist University, Kowloon Tong, Hong Kong.
[Ti] Título:NBLDA: negative binomial linear discriminant analysis for RNA-Seq data.
[So] Source:BMC Bioinformatics;17(1):369, 2016 Sep 13.
[Is] ISSN:1471-2105
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: RNA-sequencing (RNA-Seq) has become a powerful technology to characterize gene expression profiles because it is more accurate and comprehensive than microarrays. Although statistical methods that have been developed for microarray data can be applied to RNA-Seq data, they are not ideal due to the discrete nature of RNA-Seq data. The Poisson distribution and negative binomial distribution are commonly used to model count data. Recently, Witten (Annals Appl Stat 5:2493-2518, 2011) proposed a Poisson linear discriminant analysis for RNA-Seq data. The Poisson assumption may not be as appropriate as the negative binomial distribution when biological replicates are available and in the presence of overdispersion (i.e., when the variance is larger than or equal to the mean). However, it is more complicated to model negative binomial variables because they involve a dispersion parameter that needs to be estimated. RESULTS: In this paper, we propose a negative binomial linear discriminant analysis for RNA-Seq data. By Bayes' rule, we construct the classifier by fitting a negative binomial model, and propose some plug-in rules to estimate the unknown parameters in the classifier. The relationship between the negative binomial classifier and the Poisson classifier is explored, with a numerical investigation of the impact of dispersion on the discriminant score. Simulation results show the superiority of our proposed method. We also analyze two real RNA-Seq data sets to demonstrate the advantages of our method in real-world applications. CONCLUSIONS: We have developed a new classifier using the negative binomial model for RNA-seq data classification. Our simulation results show that our proposed classifier has a better performance than existing works. The proposed classifier can serve as an effective tool for classifying RNA-seq data. Based on the comparison results, we have provided some guidelines for scientists to decide which method should be used in the discriminant analysis of RNA-Seq data. R code is available at http://www.comp.hkbu.edu.hk/~xwan/NBLDA.R or https://github.com/yangchadam/NBLDA.
[Mh] Termos MeSH primário: Análise Discriminante
RNA/genética
Análise de Sequência de RNA/métodos
[Mh] Termos MeSH secundário: Teorema de Bayes
Distribuição Binomial
Seres Humanos
Transcriptoma
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
63231-63-0 (RNA)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170724
[Lr] Data última revisão:
170724
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160915
[St] Status:MEDLINE
[do] DOI:10.1186/s12859-016-1208-1


  10 / 927 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27565042
[Au] Autor:Osama A; Sayed T
[Ad] Endereço:Department of Civil Engineering, The University of British Columbia, 6250 Applied Science Lane, Vancouver, BC, V6T 1Z4, Canada. Electronic address: ahmed.osama@eng.asu.edu.eg.
[Ti] Título:Evaluating the impact of bike network indicators on cyclist safety using macro-level collision prediction models.
[So] Source:Accid Anal Prev;97:28-37, 2016 Dec.
[Is] ISSN:1879-2057
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Many cities worldwide are recognizing the important role that cycling plays in creating green and livable communities. However, vulnerable road users such as cyclists are usually subjected to an elevated level of injury risk which discourages many road users to cycle. This paper studies cyclist-vehicle collisions at 134 traffic analysis zones in the city of Vancouver to assess the impact of bike network structure on cyclist safety. Several network indicators were developed using Graph theory and their effect on cyclist safety was investigated. The indicators included measures of connectivity, directness, and topography of the bike network. The study developed several macro-level (zonal) collision prediction models that explicitly incorporated bike network indicators as explanatory variables. As well, the models incorporated the actual cyclist exposure (bike kilometers travelled) as opposed to relying on proxies such as population or bike network length. The macro-level collision prediction models were developed using generalized linear regression and full Bayesian techniques, with and without spatial effects. The models showed that cyclist collisions were positively associated with bike and vehicle exposure. The exponents of the exposure variables were less than one which supports the "safety in numbers" hypothesis. Moreover, the models showed positive associations between cyclist collisions and the bike network connectivity and linearity indicators. In contrast, negative associations were found between cyclist collisions and the bike network continuity and topography indicators. The spatial effects were statistically significant in all of the developed models.
[Mh] Termos MeSH primário: Acidentes de Trânsito/prevenção & controle
Acidentes de Trânsito/estatística & dados numéricos
Ciclismo/estatística & dados numéricos
Segurança/estatística & dados numéricos
[Mh] Termos MeSH secundário: Teorema de Bayes
Ciclismo/lesões
Distribuição Binomial
Colúmbia Britânica
Cidades
Planejamento Ambiental
Seres Humanos
Modelos Lineares
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170117
[Lr] Data última revisão:
170117
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160828
[St] Status:MEDLINE



página 1 de 93 ir para página                         
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde