Base de dados : MEDLINE
Pesquisa : E05.540 [Categoria DeCS]
Referências encontradas : 204 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 21 ir para página                         

  1 / 204 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28442907
[Au] Autor:Tang X; Li F; Jia J; Yang C; Liu W; Jin B; Wang X; Gao R; He D; Guo P
[Ad] Endereço:Department of Urology, The First Affiliated Hospital of Xi'an Jiaotong University.
[Ti] Título:Synthesis of magnetic molecularly imprinted polymers with excellent biocompatibility for the selective separation and inhibition of testosterone in prostate cancer cells.
[So] Source:Int J Nanomedicine;12:2979-2993, 2017.
[Is] ISSN:1178-2013
[Cp] País de publicação:New Zealand
[La] Idioma:eng
[Ab] Resumo:PURPOSE: Androgen plays an important role in the progression of prostate cancer. In the present study, novel magnetic molecularly imprinted polymers (MMIPs) with good biocompatibility were produced for the selective separation and inhibition of testosterone in prostate cancer cells. MATERIALS AND METHODS: MMIPs were prepared by using magnetic nanospheres, gelatin, and testosterone as the supporting materials, functional monomer, and the template molecule, respectively. The characterization of the resultant products was investigated by transmission electron microscopy, X-ray diffraction, and vibrating sample magnetometry. To test whether MMIPs can remove testosterone in biologic samples, human LNCaP (androgen-dependent) and C4-2 (androgen-independent) prostate cancer cells were selected as cell models. The translocation of androgen receptor (AR) was detected by immunofluorescence assay, and the expression of PSA mRNA was detected by real-time quantitative polymerase chain reaction analysis. Cell flow cytometry analysis was performed to detect cell cycle arrest. RESULTS: The synthesized nanomaterials (MMIPs) possessed high crystallinity, satisfactory superparamagnetic properties, and uniform imprinted shell, and exhibited high adsorption capacity, fast kinetics, and high selectivity for testosterone. Moreover, the obtained imprinted nanomaterials could selectively enrich and detect testosterone in the LNCaP cell samples as a solid-phase extractant coupled with high-performance liquid chromatography. In addition, the MMIPs could freely enter prostate cancer cells and suppress the translocation of AR into the cell nucleus. We further found that MMIPs inhibited upregulation of AR downstream target genes in LNCaP and C4-2 cells; also, MMIPs inhibited cell growth and induced obvious cell cycle arrest in androgen-dependent LNCaP cells, but had no obvious effect on androgen-independent C4-2 cells. CONCLUSION: Our results indicate that the obtained imprinted nanomaterials can specifically and effectively bind testosterone and recover it from prostate cancer cells. Moreover, the MMIPs can freely enter prostate cancer cells and block the activation of testosterone-AR pathway. Thus, the MMIPs may be a new option for antiandrogen therapy in prostate cancer.
[Mh] Termos MeSH primário: Impressão Molecular/métodos
Polímeros/farmacologia
Neoplasias da Próstata/metabolismo
Testosterona/isolamento & purificação
[Mh] Termos MeSH secundário: Adsorção
Materiais Biocompatíveis
Linhagem Celular Tumoral
Cromatografia Líquida de Alta Pressão
Compostos Ferrosos/química
Seres Humanos
Magnetismo
Magnetometria/métodos
Masculino
Microscopia Eletrônica de Transmissão
Polímeros/química
Neoplasias da Próstata/tratamento farmacológico
Extração em Fase Sólida
Testosterona/metabolismo
Difração de Raios X
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Biocompatible Materials); 0 (Ferrous Compounds); 0 (Polymers); 3XMK78S47O (Testosterone); G7036X8B5H (ferrous oxide)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170814
[Lr] Data última revisão:
170814
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170427
[St] Status:MEDLINE
[do] DOI:10.2147/IJN.S133009


  2 / 204 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28327191
[Au] Autor:Próspero AG; Quini CC; Bakuzis AF; Fidelis-de-Oliveira P; Moretto GM; Mello FP; Calabresi MF; Matos RV; Zandoná EA; Zufelato N; Oliveira RB; Miranda JR
[Ad] Endereço:Biosciences Institute of Botucatu, São Paulo State University, Botucatu, São Paulo, Brazil.
[Ti] Título:Real-time in vivo monitoring of magnetic nanoparticles in the bloodstream by AC biosusceptometry.
[So] Source:J Nanobiotechnology;15(1):22, 2017 Mar 21.
[Is] ISSN:1477-3155
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: We introduce and demonstrate that the AC biosusceptometry (ACB) technique enables real-time monitoring of magnetic nanoparticles (MNPs) in the bloodstream. We present an ACB system as a simple, portable, versatile, non-invasive, and accessible tool to study pharmacokinetic parameters of MNPs, such as circulation time, in real time. We synthesized and monitored manganese doped iron oxide nanoparticles in the bloodstream of Wistar rats using two different injection protocols. Aiming towards a translational approach, we also simultaneously evaluated cardiovascular parameters, including mean arterial pressure, heart rate, and episodes of arrhythmia in order to secure the well-being of all animals. RESULTS: We found that serial injections increased the circulation time compared with single injections. Immediately after each injection, we observed a transitory drop in arterial pressure, a small drop in heart rate, and no episodes of arrhythmia. Although some cardiovascular effects were observed, they were transitory and easily recovered in both protocols. CONCLUSIONS: These results indicate that the ACB system may be a valuable tool for in vivo, real-time MNP monitoring that allows associations with other techniques, such as pulsatile arterial pressure and electrocardiogram recordings, helping ensuring the protocol safety, which is a fundamental step towards clinical applications.
[Mh] Termos MeSH primário: Tempo de Circulação Sanguínea
Compostos Férricos/sangue
Nanopartículas de Magnetita/química
Magnetometria/métodos
[Mh] Termos MeSH secundário: Animais
Arritmias Cardíacas/induzido quimicamente
Pressão Sanguínea
Eletrocardiografia
Compostos Férricos/farmacocinética
Frequência Cardíaca
Magnetismo
Masculino
Tamanho da Partícula
Ratos
Ratos Wistar
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Ferric Compounds); 0 (Magnetite Nanoparticles); 1K09F3G675 (ferric oxide)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170512
[Lr] Data última revisão:
170512
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170323
[St] Status:MEDLINE
[do] DOI:10.1186/s12951-017-0257-6


  3 / 204 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28316987
[Au] Autor:Liu Y; Wang Y; Yan M; Huang J
[Ad] Endereço:School of Basic Medical Sciences, Xinxiang Medical University, Jinsui Avenue 601, Xinxiang, Henan 453003, China; Henan Collaborative Innovation Center of Molecular Diagnostics and Laboratory Medicine, Jinsui Avenue 601, Xinxiang, Henan 453003, China.
[Ti] Título:Selective Removal of Hemoglobin from Blood Using Hierarchical Copper Shells Anchored to Magnetic Nanoparticles.
[So] Source:Biomed Res Int;2017:7309481, 2017.
[Is] ISSN:2314-6141
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Hierarchical copper shells anchored on magnetic nanoparticles were designed and fabricated to selectively deplete hemoglobin from human blood by immobilized metal affinity chromatography. Briefly, CoFe O nanoparticles coated with polyacrylic acid were first synthesized by a one-pot solvothermal method. Hierarchical copper shells were then deposited by immobilizing Cu on nanoparticles and subsequently by reducing between the solid CoFe O @COOH and copper solution with NaBH . The resulting nanoparticles were characterized by scanning electron microscopy, transmission electron microscopy, Fourier transform infrared spectrometry, X-ray photoelectron spectroscopy, and vibrating sample magnetometry. The particles were also tested against purified bovine hemoglobin over a range of pH, contact time, and initial protein concentration. Hemoglobin adsorption followed pseudo-second-order kinetics and reached equilibrium in 90 min. Isothermal data also fit the Langmuir model well, with calculated maximum adsorption capacity 666 mg g . Due to the high density of Cu on the shell, the nanoparticles efficiently and selectively deplete hemoglobin from human blood. Taken together, the results demonstrate that the particles with hierarchical copper shells effectively remove abundant, histidine-rich proteins, such as hemoglobin from human blood, and thereby minimize interference in diagnostic and other assays.
[Mh] Termos MeSH primário: Cobre/química
Hemoglobinas/análise
Hemoglobinas/isolamento & purificação
Nanopartículas de Magnetita/química
[Mh] Termos MeSH secundário: Resinas Acrílicas/química
Adsorção
Animais
Bovinos
Histidina/química
Seres Humanos
Concentração de Íons de Hidrogênio
Cinética
Magnetismo
Magnetometria
Microscopia Eletrônica de Varredura
Microscopia Eletrônica de Transmissão
Nanocompostos/química
Espectroscopia Fotoeletrônica
Proteínas/química
Espectrofotometria Ultravioleta
Espectroscopia de Infravermelho com Transformada de Fourier
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Acrylic Resins); 0 (Hemoglobins); 0 (Magnetite Nanoparticles); 0 (Proteins); 0 (histidine-rich proteins); 4Q93RCW27E (carbopol 940); 4QD397987E (Histidine); 789U1901C5 (Copper)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170417
[Lr] Data última revisão:
170417
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170321
[St] Status:MEDLINE
[do] DOI:10.1155/2017/7309481


  4 / 204 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28249829
[Au] Autor:Jost GF; Walti J; Mariani L; Schaeren S; Cattin P
[Ad] Endereço:Department of Spine Surgery, University Hospital Basel, Basel, Switzerland. Electronic address: gregory.jost@icloud.com.
[Ti] Título:Inertial Measurement Unit-Assisted Implantation of Thoracic, Lumbar, and Sacral Pedicle Screws Improves Precision of a Freehand Technique.
[So] Source:World Neurosurg;103:11-18, 2017 Jul.
[Is] ISSN:1878-8769
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: A method applying inertial measurement units (IMUs) was developed to implant pedicle screws in the thoracic and lumbosacral spine. This was compared with a freehand technique. METHODS: The study was done on 9 human cadavers. For each cadaver, a preoperative computed tomography (CT) scan was performed to measure the axial and sagittal tilt angles of the screw trajectories from T1 to S1. After the entry points were defined on the exposed spine, the IMU-equipped pedicle finder and screwdriver were used to reproduce these tilt angles and implant half of the screws. The other half was implanted with a freehand technique. Fluoroscopy was not used. The screw trajectories were analyzed on postoperative CTs. RESULTS: A hundred and sixty-two screws were placed with use of the IMUs and 162 screws were implanted by freehand. The IMU-guided technique matched the planned trajectories significantly better than the freehand technique (axial tilt P < 0.001, sagittal tilt P < 0.001). With IMU assistance, the mean offsets between the planned and postoperatively measured tilt angles of the screws were 3.3 degrees ± 3.5 degrees for the axial plane (median 2 degrees, range 0-23 degrees) and 3.4 degrees ± 3 degrees for the sagittal plane (median 3 degrees, range 0-13 degrees). For the freehand technique, the mean offsets between the planned and postoperatively measured tilt angles of the screws were 5.6 degrees ± 4.5 degrees for the axial plane (median 5 degrees, range 0-31 degrees) and 6.7 degrees ± 5.4 degrees for the sagittal plane (median 6 degrees, range 0-33 degrees). CONCLUSIONS: IMU-assisted implantation of pedicle screws may enhance the performance of a freehand technique in the thoracic and lumbosacral spine.
[Mh] Termos MeSH primário: Vértebras Lombares/cirurgia
Parafusos Pediculares
Sacro/cirurgia
Equipamentos Cirúrgicos
Vértebras Torácicas/cirurgia
[Mh] Termos MeSH secundário: Aceleração
Acelerometria/instrumentação
Idoso
Idoso de 80 Anos ou mais
Cadáver
Feminino
Seres Humanos
Imagem Tridimensional
Vértebras Lombares/diagnóstico por imagem
Magnetometria/instrumentação
Masculino
Meia-Idade
Rotação
Sacro/diagnóstico por imagem
Vértebras Torácicas/diagnóstico por imagem
Tomografia Computadorizada por Raios X
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170925
[Lr] Data última revisão:
170925
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170303
[St] Status:MEDLINE


  5 / 204 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27992324
[Au] Autor:Sargolzaei S; Elahi H; Sokoloff A; Ghovanloo M
[Ti] Título:A Dual-Mode Magnetic-Acoustic System for Monitoring Fluid Intake Behavior in Animals.
[So] Source:IEEE Trans Biomed Eng;64(9):2090-2097, 2017 Sep.
[Is] ISSN:1558-2531
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:We have developed an unobtrusive magnetic-acoustic fluid intake monitoring (MAFIM) system using a conventional stainless-steel roller-ball nipple to measure licking and drinking behavior in animals. Movements of a small permanent magnetic tracer attached to stainless-steel roller balls that operate as a tongue-actuated valve are sensed by a pair of three-axial magnetometers, and transformed into a time-series indicating the status of the ball (up or down), using a Gaussian mixture model based data-driven classifier. The sounds produced by the rise and fall of the roller balls are also recorded and classified to substantiate the magnetic data by an independent modality for a more robust solution. The operation of the magnetic and acoustic sensors is controlled by an embedded system, communicating via Universal Serial Bus (USB) with a custom-designed user interface, running on a PC. The MAFIM system has been tested in vivo with minipigs, accurately measuring various drinking parameters and licking patterns without constraints imposed by current lick monitoring systems, such as nipple access, animal-nipple contact, animal training, and complex parameter settings.
[Mh] Termos MeSH primário: Comportamento de Ingestão de Líquido/fisiologia
Ingestão de Líquidos/fisiologia
Comportamento Alimentar/fisiologia
Magnetometria/instrumentação
Sistemas Microeletromecânicos/instrumentação
Espectrografia do Som/instrumentação
[Mh] Termos MeSH secundário: Acústica/instrumentação
Animais
Desenho de Equipamento
Análise de Falha de Equipamento
Reprodutibilidade dos Testes
Sensibilidade e Especificidade
Suínos
Porco Miniatura
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171024
[Lr] Data última revisão:
171024
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161220
[St] Status:MEDLINE
[do] DOI:10.1109/TBME.2016.2638545


  6 / 204 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27891637
[Au] Autor:Eswaran H; Escalona-Vargas D; Bolin EH; Wilson JD; Lowery CL
[Ad] Endereço:Department of Obstetrics and Gynecology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
[Ti] Título:Fetal magnetocardiography using optically pumped magnetometers: a more adaptable and less expensive alternative?
[So] Source:Prenat Diagn;37(2):193-196, 2017 Feb.
[Is] ISSN:1097-0223
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Fetal magnetocardiography provides the requisite precision for diagnostic measurement of electrophysiological events in the fetal heart. Despite its significant benefits, this technique with current cryogenic based sensors has been limited to few centers, due to high cost of maintenance. In this study, we show that a less expensive non-cryogenic alternative, optically pumped magnetometers, can provide similar electrophysiological and quantitative characteristics when subjected to direct comparison with the current technology. Further research can potentially increase its clinical use for fetal magnetocardiography. © 2016 John Wiley & Sons, Ltd.
[Mh] Termos MeSH primário: Coração Fetal/diagnóstico por imagem
Magnetocardiografia/instrumentação
Magnetocardiografia/métodos
Diagnóstico Pré-Natal
[Mh] Termos MeSH secundário: Análise Custo-Benefício
Estudos de Viabilidade
Feminino
Seres Humanos
Magnetocardiografia/economia
Magnetometria/economia
Magnetometria/instrumentação
Magnetometria/métodos
Óptica e Fotônica/instrumentação
Gravidez
Terceiro Trimestre da Gravidez
Diagnóstico Pré-Natal/economia
Diagnóstico Pré-Natal/instrumentação
Diagnóstico Pré-Natal/métodos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170926
[Lr] Data última revisão:
170926
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161129
[St] Status:MEDLINE
[do] DOI:10.1002/pd.4976


  7 / 204 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27217073
[Au] Autor:Milosevic I; Motte L; Aoun B; Li T; Ren Y; Sun C; Saboungi ML
[Ad] Endereço:Powder Technology Laboratory, Ecole Polytechnique Federale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland.
[Ti] Título:Effects of coating spherical iron oxide nanoparticles.
[So] Source:Biochim Biophys Acta;1861(1 Pt B):3621-3626, 2017 01.
[Is] ISSN:0006-3002
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:We investigate the effect of several coatings applied in biomedical applications to iron oxide nanoparticles on the size, structure and composition of the particles. The four structural techniques employed - TEM, DLS, VSM, SAXS and EXAFS - show no significant effects of the coatings on the spherical shape of the bare nanoparticles, the average sizes or the local order around the Fe atoms. The NPs coated with hydroxylmethylene bisphosphonate or catechol have a lower proportion of magnetite than the bare and citrated ones, raising the question whether the former are responsible for increasing the valence state of the oxide on the NP surfaces and lowering the overall proportion of magnetite in the particles. VSM measurements show that these two coatings lead to a slightly higher saturation magnetization than the citrate. This article is part of a Special Issue entitled "Science for Life" Guest Editor: Dr. Austen Angell, Dr. Salvatore Magazù and Dr. Federica Migliardo.
[Mh] Termos MeSH primário: Materiais Revestidos Biocompatíveis/química
Compostos Férricos/química
Nanopartículas/química
[Mh] Termos MeSH secundário: Difusão Dinâmica da Luz
Hidrodinâmica
Concentração de Íons de Hidrogênio
Magnetometria
Nanopartículas/ultraestrutura
Tamanho da Partícula
Espalhamento a Baixo Ângulo
Espectroscopia de Infravermelho com Transformada de Fourier
Eletricidade Estática
Espectroscopia por Absorção de Raios X
Difração de Raios X
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Coated Materials, Biocompatible); 0 (Ferric Compounds); 1K09F3G675 (ferric oxide)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170613
[Lr] Data última revisão:
170613
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160525
[St] Status:MEDLINE


  8 / 204 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28269056
[Au] Autor:Mlynczak M; Berka M; Niewiadomski W; Cybulski G
[Ti] Título:Body position classification for cardiorespiratory measurement.
[So] Source:Conf Proc IEEE Eng Med Biol Soc;2016:3515-3518, 2016 08.
[Is] ISSN:1557-170X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Heart activity, or at least heart rate variability, is associated with body position. Our previous studies have confirmed that impedance pneumography may be used to record respiratory function, but the calibration coefficients for this method depend on position. Data were collected from 24 students (12 male, 12 female), who alternated positions between lying (on front, back, and right side), sitting and standing. Signals from an attached iPhone's internal sensors (accelerometer, gyroscope, magnetometer) were recorded and attitude relative to gravity was calculated. The signals were subsequently segmented and marked. Five algorithms were trained and cross-validated for different sensor combinations. Without differentiation of sitting and standing, 100% accuracy was achieved using all algorithms. The classifier best differentiating these two states was based on random forests, with overall accuracy of 90%. Simple methods based on a proposed hybrid classifier were tested for online measurement without the need for signal segmentation, with 99% accuracy. The prospect of the algorithms' use in long-term studies (particularly cardiorespiratory monitoring) was assessed.
[Mh] Termos MeSH primário: Algoritmos
Postura/fisiologia
[Mh] Termos MeSH secundário: Acelerometria/instrumentação
Acelerometria/métodos
Calibragem
Feminino
Determinação da Frequência Cardíaca
Seres Humanos
Magnetometria/instrumentação
Magnetometria/métodos
Masculino
Processamento de Sinais Assistido por Computador
Smartphone
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1706
[Cu] Atualização por classe:171121
[Lr] Data última revisão:
171121
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170309
[St] Status:MEDLINE
[do] DOI:10.1109/EMBC.2016.7591486


  9 / 204 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28269024
[Au] Autor:Tadayon P; Felderhoff T; Knopp A; Staude G
[Ti] Título:Fusion of inertial and magnetic sensors for 3D position and orientation estimation.
[So] Source:Conf Proc IEEE Eng Med Biol Soc;2016:3362-3365, 2016 08.
[Is] ISSN:1557-170X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:This paper presents a new method for 3D position and orientation estimation based on the magnetic field generated by a single coil and the fusion of low power magnetometers and inertial sensors. The fixed spatial relationship between the sensors is exploited to solve the ambiguity problem that occurs when only a single coil is employed. In this context a new positioning algorithm is developed and verified by simulations. Using a single coil instead of three coils as common in conventional magnetic field based systems brings a benefit both regarding power consumption and construction size. Moreover, as the proposed system requires no line of sight between source and sensors, it is ideally suited for portable, location-independent applications such as the mobile assessment of a persons' head to torso posture and movement e.g. for the purpose of examining causes for chronic pain in the cervical spine area under conditions of daily life.
[Mh] Termos MeSH primário: Magnetometria/métodos
Postura/fisiologia
[Mh] Termos MeSH secundário: Algoritmos
Simulação por Computador
Cabeça
Seres Humanos
Campos Magnéticos
Magnetometria/instrumentação
Monitorização Fisiológica/instrumentação
Monitorização Fisiológica/métodos
Movimento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1707
[Cu] Atualização por classe:171121
[Lr] Data última revisão:
171121
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170309
[St] Status:MEDLINE
[do] DOI:10.1109/EMBC.2016.7591448


  10 / 204 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27890536
[Au] Autor:Crabolu M; Pani D; Raffo L; Cereatti A
[Ad] Endereço:Department of Electrical and Electronic Engineering, University of Cagliari, Piazza d'Armi, 09123 Cagliari, Italy. Electronic address: michele.crabolu@diee.unica.it.
[Ti] Título:Estimation of the center of rotation using wearable magneto-inertial sensors.
[So] Source:J Biomech;49(16):3928-3933, 2016 Dec 08.
[Is] ISSN:1873-2380
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Determining the center of rotation (CoR) of joints is fundamental to the field of human movement analysis. CoR can be determined using a magneto-inertial measurement unit (MIMU) using a functional approach requiring a calibration exercise. We systematically investigated the influence of different experimental conditions that can affect precision and accuracy while estimating the CoR, such as (a) angular joint velocity, (b) distance between the MIMU and the CoR, (c) type of the joint motion implemented, (d) amplitude of the angular range of motion, (e) model of the MIMU used for data recording, (f) amplitude of additive noise on inertial signals, and (g) amplitude of the errors in the MIMU orientation. The evaluation process was articulated at three levels: assessment through experiments using a mechanical device, mathematical simulation, and an analytical propagation model of the noise. The results reveal that joint angular velocity significantly impacted CoR identification, and hence, slow joint movement should be avoided. An accurate estimation of the MIMU orientation is also fundamental for accurately subtracting the contribution owing to gravity to obtain the coordinate acceleration. The unit should be preferably attached close to the CoR, but both type and range of motion do not appear to be critical. When the proposed methodology is correctly implemented, error in the CoR estimates is expected to be <3mm (best estimates=2±0.5mm). The findings of the present study foster the need to further investigate this methodology for application in human subjects.
[Mh] Termos MeSH primário: Movimento
[Mh] Termos MeSH secundário: Algoritmos
Fenômenos Biomecânicos
Calibragem
Seres Humanos
Articulações/fisiologia
Magnetometria
Modelos Biológicos
Orientação
Exame Físico/métodos
Postura
Amplitude de Movimento Articular
Razão Sinal-Ruído
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171010
[Lr] Data última revisão:
171010
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161129
[St] Status:MEDLINE



página 1 de 21 ir para página                         
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde