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  1 / 1847 MEDLINE  
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[PMID]:29267662
[Au] Autor:Santos PSD; Pedrotti D; Braga MM; Rocha RO; Lenzi TL
[Ad] Endereço:Universidade Federal de Santa Maria - UFSM, School of Dentistry, Santa Maria, RS, Brazil.
[Ti] Título:Materials used for indirect pulp treatment in primary teeth: a mixed treatment comparisons meta-analysis.
[So] Source:Braz Oral Res;31:e101, 2017 Dec 18.
[Is] ISSN:1807-3107
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:This study aimed to systematically review the literature to address the question regarding the influence of different materials in the clinical and radiographic success of indirect pulp treatment in primary teeth. A literature search was carried out for articles published prior to January 2017 in PubMed/MEDLINE, CENTRAL, Scopus, TRIP and ClinicalTrials databases; relevant articles included randomized clinical trials that compared materials used for indirect pulp treatment in primary teeth. Two reviewers independently selected the studies and extracted the data. The effects of each material on the outcome (clinical and radiographic failures) were analyzed using a mixed treatment comparisons meta-analysis. The ranking of treatments according to their probability of being the best choice was also calculated. From 1,088 potentially eligible studies, 11 were selected for full-text analysis, and 4 were included in the meta-analysis. In all papers, calcium hydroxide liner was used as the control group versus an adhesive system, resin-modified glass ionomer cement or placebo. The follow-up period ranged from 24 to 48 months, with dropout rates of 0-25.7%. The material type did not significantly affect the risk of failure of the indirect pulp treatment. However, calcium hydroxide presented a higher probability of failure. In conclusion, there is no scientific evidence showing the superiority of any material used for indirect pulp treatment in primary teeth.
[Mh] Termos MeSH primário: Hidróxido de Cálcio/uso terapêutico
Capeamento da Polpa Dentária/métodos
Polpa Dentária/efeitos dos fármacos
Cimentos de Ionômeros de Vidro/uso terapêutico
Guta-Percha/uso terapêutico
Dente Decíduo/efeitos dos fármacos
[Mh] Termos MeSH secundário: Cárie Dentária/terapia
Seres Humanos
Viés de Publicação
Radiografia Dentária
Dente Decíduo/diagnóstico por imagem
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE; META-ANALYSIS; REVIEW
[Nm] Nome de substância:
0 (Glass Ionomer Cements); 9000-32-2 (Gutta-Percha); PF5DZW74VN (Calcium Hydroxide)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:171222
[St] Status:MEDLINE


  2 / 1847 MEDLINE  
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[PMID]:28675004
[Au] Autor:Dingming H; Qian L; Qian L; Ling Y; Xuedong Z
[Ad] Endereço:State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Dept. of Conservative Dentistry and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
[Ti] Título:[Confusion and solution for vital pulp therapy].
[So] Source:Hua Xi Kou Qiang Yi Xue Za Zhi;35(3):227-231, 2017 Jun 01.
[Is] ISSN:1000-1182
[Cp] País de publicação:China
[La] Idioma:chi
[Ab] Resumo:Dental pulp tissue plays a role in forming dentin, providing nutrition, conducting pain, and generating protective responses to environmental stimuli. Bacterial infection is the main cause of pulp disease, where histopathological changes are the histological basis for determining the choice of treatment and the evaluation of therapeutic effect. Thus, particular attention should be given to eliminate infection, as well as preserve and maintain pulpal health in teeth that show reversible or limited pulpal injuries. Vital pulp therapy, especially its indications and prognostic factors, has been a research hotspot that often causes confusion among clinicians. In this paper, we briefly introduce the confusion and solution for vital pulp therapy in terms of indications, pulp condition assessment, infection elimination, and capping material selection. In addition, we develop a clinical pathway and an operation normalization of vital pulp therapy to better perform the therapy.
[Mh] Termos MeSH primário: Doenças da Polpa Dentária
Dentina Secundária
[Mh] Termos MeSH secundário: Assistência Odontológica
Polpa Dentária
Capeamento da Polpa Dentária
Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170807
[Lr] Data última revisão:
170807
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:170705
[St] Status:MEDLINE
[do] DOI:10.7518/hxkq.2017.03.001


  3 / 1847 MEDLINE  
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[PMID]:28571484
[Au] Autor:Collignon AM; Amri N; Lesieur J; Sadoine J; Ribes S; Menashi S; Simon S; Berdal A; Rochefort GY; Chaussain C; Gaucher C
[Ad] Endereço:1 EA 2496 Laboratory Orofacial Pathologies, Imagery and Biotherapies, Dental School and Life imaging Platform (PIV), University Paris Descartes Sorbonne Paris Cité, Montrouge, France.
[Ti] Título:Sclerostin Deficiency Promotes Reparative Dentinogenesis.
[So] Source:J Dent Res;96(7):815-821, 2017 Jul.
[Is] ISSN:1544-0591
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:In humans, the SOST gene encodes sclerostin, an inhibitor of bone growth and remodeling, which also negatively regulates the bone repair process. Sclerostin has also been implicated in tooth formation, but its potential role in pulp healing remains unknown. The aim of this study was to explore the role of sclerostin in reparative dentinogenesis using Sost knockout mice ( Sost ). The pulps of the first maxillary molars were mechanically exposed in 3-mo-old Sost and wild-type (WT) mice ( n = 14 mice per group), capped with mineral trioxide aggregate cement, and the cavities were filled with a bonded composite resin. Reparative dentinogenesis was dynamically followed up by micro-computed tomography and characterized by histological analyses. Presurgical analysis revealed a significantly lower pulp volume in Sost mice compared with WT. At 30 and 49 d postsurgery, a large-forming reparative mineralized bridge, associated with osteopontin-positive mineralization foci, was observed in the Sost pulps, whereas a much smaller bridge was detected in WT. At the longer time points, the bridge, which was associated with dentin sialoprotein-positive cells, had expanded in both groups but remained significantly larger in Sost pulps. Sclerostin expression in the healing WT pulps was detected in the cells neighboring the forming dentin bridge. In vitro, mineralization induced by Sost dental pulp cells (DPCs) was also dramatically enhanced when compared with WT DPCs. These observations were associated with an increased Sost expression in WT cells. Taken together, our data show that sclerostin deficiency hastened reparative dentinogenesis after pulp injury, suggesting that the inhibition of sclerostin may constitute a promising therapeutic strategy for improving the healing of damaged pulps.
[Mh] Termos MeSH primário: Polpa Dentária/citologia
Dentinogênese/genética
Glicoproteínas/genética
[Mh] Termos MeSH secundário: Compostos de Alumínio
Animais
Compostos de Cálcio
Resinas Compostas
Capeamento da Polpa Dentária/métodos
Combinação de Medicamentos
Glicoproteínas/deficiência
Técnicas Imunoenzimáticas
Camundongos
Camundongos Endogâmicos C57BL
Camundongos Knockout
Dente Molar/cirurgia
Óxidos
Reação em Cadeia da Polimerase Via Transcriptase Reversa
Silicatos
Microtomografia por Raio-X
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Aluminum Compounds); 0 (Calcium Compounds); 0 (Composite Resins); 0 (Drug Combinations); 0 (Glycoproteins); 0 (Oxides); 0 (Silicates); 0 (Sost protein, mouse); 0 (mineral trioxide aggregate)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170828
[Lr] Data última revisão:
170828
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:170603
[St] Status:MEDLINE
[do] DOI:10.1177/0022034517698104


  4 / 1847 MEDLINE  
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[PMID]:28410008
[Au] Autor:Bjørndal L; Fransson H; Bruun G; Markvart M; Kjældgaard M; Näsman P; Hedenbjörk-Lager A; Dige I; Thordrup M
[Ad] Endereço:1 Department of Odontology, University of Copenhagen, Copenhagen, Denmark.
[Ti] Título:Randomized Clinical Trials on Deep Carious Lesions: 5-Year Follow-up.
[So] Source:J Dent Res;96(7):747-753, 2017 Jul.
[Is] ISSN:1544-0591
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Deep caries presents a dilemma in terms of which treatment that will render an optimal prognosis by maintaining pulp vitality with absence of apical pathology. Previously, 2 randomized clinical trials were performed testing the short-term effects of stepwise carious tissue removal versus nonselective carious removal to hard dentin with or without pulp exposure. The aim of this article was to report the 5-y outcome on these previously treated patients having radiographically well-defined carious lesions extending into the pulpal quarter of the dentin but with a well-defined radiodense zone between the carious lesion and the pulp. In this long-term study, 239 of 314 (76.2%) patients were analyzed. The stepwise removal group had a significantly higher proportion of success (60.2%) at 5-y follow-up compared with the nonselective carious removal to hard dentin group (46.3%) ( P = 0.031) when pulp exposures per se were included as failures. Pulp exposure rate was significantly lower in the stepwise carious removal group (21.2% vs. 35.5%; P = 0.014). Irrespective of pulp exposure status, the difference (13.3%) was still significant when sustained pulp vitality without apical radiolucency and unbearable pain was considered (95% confidence interval, 3.1-26.3, P = 0.045). After pulp exposure, only 9% ( n = 4) of the analyzed patients were assessed as successful, indicating that the prognosis is highly dubious following conventional pulp-capping procedures (direct pulp capping or partial pulpotomy) in deep carious lesions in adults. In conclusion, the stepwise carious removal group had a significantly higher proportion of pulps with sustained vitality without apical radiolucency versus nonselective carious removal of deep carious lesions in adult teeth at 5-y follow-up ( ClinicalTrials.gov NCT00187837 and NCT00187850).
[Mh] Termos MeSH primário: Cárie Dentária/terapia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Cárie Dentária/diagnóstico por imagem
Capeamento da Polpa Dentária/métodos
Exposição da Polpa Dentária/terapia
Feminino
Seguimentos
Seres Humanos
Masculino
Meia-Idade
Prognóstico
Pulpotomia/métodos
Ensaios Clínicos Controlados Aleatórios como Assunto
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE; MULTICENTER STUDY
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170828
[Lr] Data última revisão:
170828
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:170415
[St] Status:MEDLINE
[do] DOI:10.1177/0022034517702620


  5 / 1847 MEDLINE  
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[PMID]:28253279
[Au] Autor:Liu Q; Ma Y; Wang J; Zhu X; Yang Y; Mei Y
[Ad] Endereço:Key Laboratory of Oral Diseases of Jiangsu Province and Stomatological School of Nanjing Medical University, Nanjing, Jiangsu, China.
[Ti] Título:Demineralized bone matrix used for direct pulp capping in rats.
[So] Source:PLoS One;12(3):e0172693, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: To evaluate the wound healing process following direct pulp capping with demineralized bone matrix (DBM) and calcium hydroxide (Ca(OH)2). METHODS: Fifty 8-weeks-old SPF Wistar male rats were divided into two groups: one was the DBM treated group, and the other was the Ca(OH)2 treated group. Pulpotomy was performed on the maxillary first molar of one side of each rat, and the another side was left as the blank control. Rats were sacrificed after each observation period (1, 3, 7, 14 and 28 days) and specimen slices were made. Hematoxylin-Eosin (HE) staining was used for observing the changes of pulp tissue, and immunohistochemical staining was used for observing the expression of reparative dentinogenesis-related factors runt transcription factor 2 (Runx2), type I collagen (COL I), osteocalcin (OCN) and dentin sialoprotein (DSP). RESULTS: Inflammatory cell infiltration (ICI) and pulp tissue disorganization (PTD) could be observed in both the DBM and Ca(OH)2 groups at all observation periods. The DBM group showed slighter ICI on 1 and 28 days and milder PTD on 28 days, with a significant difference (P<0.05). Reparative dentin formation (RDF) could initially be observed on 14 days postoperatively, and the DBM group showed more regular and thinner RDF with significant differences on 14 and 28 days compared with the Ca(OH)2 group (P<0.05). In both groups, the expression of Runx2, COL I, DSP and OCN were positive. Generally, the expression of these four factors in the DBM group was stronger than the Ca(OH)2 group on the same observation periods. CONCLUSIONS: DBM had the ability of inducing odontoblast differentiation and promoting dentinogenesis. DBM could initiate physiologic wound healing in pulp and had the ability to promote reparative dentin formation. Consequently, DBM may be an acceptable alternative for direct pulp capping.
[Mh] Termos MeSH primário: Osso e Ossos/citologia
Capeamento da Polpa Dentária
Matriz Extracelular/metabolismo
[Mh] Termos MeSH secundário: Animais
Calcificação Fisiológica
Hidróxido de Cálcio/farmacologia
Masculino
Ratos
Ratos Wistar
Cicatrização/efeitos dos fármacos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
PF5DZW74VN (Calcium Hydroxide)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170825
[Lr] Data última revisão:
170825
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170303
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0172693


  6 / 1847 MEDLINE  
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[PMID]:28232937
[Au] Autor:Jun SK; Lee JH; Lee HH
[Ad] Endereço:Department of Biomaterials Science, College of Dentistry, Dankook University, Cheonan, Republic of Korea.
[Ti] Título:The Biomineralization of a Bioactive Glass-Incorporated Light-Curable Pulp Capping Material Using Human Dental Pulp Stem Cells.
[So] Source:Biomed Res Int;2017:2495282, 2017.
[Is] ISSN:2314-6141
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The aim of this study was to investigate the biomineralization of a newly introduced bioactive glass-incorporated light-curable pulp capping material using human dental pulp stem cells (hDPSCs). The product (Bioactive® [BA]) was compared with a conventional calcium hydroxide-incorporated (Dycal [DC]) and a light-curable (Theracal® [TC]) counterpart. Eluates from set specimens were used for investigating the cytotoxicity and biomineralization ability, determined by alkaline phosphatase (ALP) activity and alizarin red staining (ARS). Cations and hydroxide ions in the extracts were measured. An hDPSC viability of less than 70% was observed with 50% diluted extract in all groups and with 25% diluted extract in the DC. Culturing with 12.5% diluted BA extract statistically lowered ALP activity and biomineralization compared to DC ( < 0.05), but TC did not ( > 0.05). Ca (~110 ppm) and hydroxide ions (pH 11) were only detected in DC and TC. Ionic supplement-added BA, which contained similar ion concentrations as TC, showed similar ARS mineralization compared to TC. In conclusion, the BA was similar to, yet more cytotoxic to hDPSCs than, its DC and TC. The BA was considered to stimulate biomineralization similar to DC and TC only when it released a similar amount of Ca and hydroxide ions.
[Mh] Termos MeSH primário: Luzes de Cura Dentária
Materiais Dentários/farmacologia
Capeamento da Polpa Dentária
Polpa Dentária/citologia
Vidro/química
Minerais/química
Células-Tronco/citologia
[Mh] Termos MeSH secundário: Sobrevivência Celular/efeitos dos fármacos
Seres Humanos
Íons
Espectrofotometria Atômica
Células-Tronco/efeitos dos fármacos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Dental Materials); 0 (Ions); 0 (Minerals)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170306
[Lr] Data última revisão:
170306
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170225
[St] Status:MEDLINE
[do] DOI:10.1155/2017/2495282


  7 / 1847 MEDLINE  
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[PMID]:28190811
[Au] Autor:Shinkai K; Taira Y; Kawashima S; Suzuki S; Suzuki M
[Ad] Endereço:Department of Operative Dentistry, The Nippon Dental University School of Life Dentistry at Niigata.
[Ti] Título:Histological evaluation of direct pulp capping with all-in-one adhesives in rat teeth.
[So] Source:Dent Mater J;36(3):348-356, 2017 May 31.
[Is] ISSN:1881-1361
[Cp] País de publicação:Japan
[La] Idioma:eng
[Ab] Resumo:The aim of this study was to histologically evaluate direct pulp capping using different all-in-one adhesives in rat teeth. Five all-in-one adhesives and a control material (MTA) were used. Each material was applied on the exposed pulp, and each cavity was subsequently restored with the resin composite. Rats were sacrificed 14 days after the surgical procedure. Serial stained sections were histologically evaluated for examining pulp tissue disorganization (PTD), inflammatory cell infiltration (ICI), dentin bridge formation (DBF), and bacterial penetration (BP). We found that rat pulps, which were direct capped with all-in-one adhesives, showed various degrees of PTD, ICI, and DBF depending on the material, and that there were no complete dentin bridges. In contrast, rat pulps capped with MTA showed no PTD and ICI, and there were complete dentin bridges in all, but one specimen. No BP was observed in any specimen.
[Mh] Termos MeSH primário: Adesivos
Capeamento da Polpa Dentária
[Mh] Termos MeSH secundário: Animais
Hidróxido de Cálcio
Polpa Dentária
Exposição da Polpa Dentária
Dentina Secundária
Ratos
Cimentos de Resina
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Adhesives); 0 (Resin Cements); PF5DZW74VN (Calcium Hydroxide)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170823
[Lr] Data última revisão:
170823
[Sb] Subgrupo de revista:D
[Da] Data de entrada para processamento:170214
[St] Status:MEDLINE
[do] DOI:10.4012/dmj.2016-148


  8 / 1847 MEDLINE  
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[PMID]:28117776
[Au] Autor:Song M; Kim S; Kim T; Park S; Shin KH; Kang M; Park NH; Kim R
[Ad] Endereço:The Shapiro Family Laboratory of Viral Oncology and Aging Research, The UCLA School of Dentistry.
[Ti] Título:Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice.
[So] Source:J Vis Exp;(119), 2017 Jan 12.
[Is] ISSN:1940-087X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Dental pulp is a vital organ of a tooth fully protected by enamel and dentin. When the pulp is exposed due to cariogenic or iatrogenic injuries, it is often capped with biocompatible materials in order to expedite pulpal wound healing. The ultimate goal is to regenerate reparative dentin, a physical barrier that functions as a "biological seal" and protects the underlying pulp tissue. Although this direct pulp-capping procedure has long been used in dentistry, the underlying molecular mechanism of pulpal wound healing and reparative dentin formation is still poorly understood. To induce reparative dentin, pulp capping has been performed experimentally in large animals, but less so in mice, presumably due to their small sizes and the ensuing technical difficulties. Here, we present a detailed, step-by-step method of performing a pulp-capping procedure in mice, including the preparation of a Class-I-like cavity, the placement of pulp-capping materials, and the restoration procedure using dental composite. Our pulp-capping mouse model will be instrumental in investigating the fundamental molecular mechanisms of pulpal wound healing in the context of reparative dentin in vivo by enabling the use of transgenic or knockout mice that are widely available in the research community.
[Mh] Termos MeSH primário: Capeamento da Polpa Dentária/métodos
Exposição da Polpa Dentária/fisiopatologia
Dentina Secundária/fisiologia
Cicatrização
[Mh] Termos MeSH secundário: Animais
Camundongos
[Pt] Tipo de publicação:JOURNAL ARTICLE; VIDEO-AUDIO MEDIA
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170927
[Lr] Data última revisão:
170927
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170125
[St] Status:MEDLINE
[do] DOI:10.3791/54973


  9 / 1847 MEDLINE  
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[PMID]:27986375
[Au] Autor:Negm AM; Hassanien EE; Abu-Seida AM; Nagy MM
[Ad] Endereço:Department of Endodontic, Faculty of Dentistry, October 6 University, Egypt.
[Ti] Título:Biological evaluation of a new pulp capping material developed from Portland cement.
[So] Source:Exp Toxicol Pathol;69(3):115-122, 2017 Mar 02.
[Is] ISSN:1618-1433
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:This study evaluates the biological properties of a new pulp capping material developed from Portland cement. This study was conducted on 48 teeth in 4 dogs (12 teeth/dog). The dogs were classified into two equal groups (n=24 teeth) according to the evaluation period including: group A (3 weeks) and group B (3 months). Each group was further subdivided into three equal subgroups (n=8 teeth) according to the capping material including: subgroup 1: mineral trioxide aggregate (MTA), subgroup2: Portland cement+10% calcium hydroxide+20% bismuth oxide (Port Cal) and subgroup 3: Portland cement+bismuth oxide. After general anesthesia, a class V buccal cavity was prepared coronal to the gingival margin. After pulp exposure and hemostasis,the capping materials and glass ionomer filling were placed on the exposure sites. All histopathological findings, inflammatory cell count and dentin bridge formation were recorded. Data were analyzed statistically. After 3 months, the histopathological picture of the pulp in subgroup 1 showed normal pulp, continuous odontoblastic layer and complete dentin bridge formation while subgroup 2 showed partial and complete dentin bridge over a normal and necrotic pulps. Subgroup 3 showed loss of normal architecture, areas of necrosis, complete, or incomplete dentin bridge formation, attached and detached pulp stones and fatty degeneration in group B. For group A, MTA subgroup showed the least number of inflammatory cell infiltrate followed by Port Cal subgroup. While subgroup 3 showed the highest number of inflammatory cell infiltrate. For group B, the mean inflammatory cell count increased with the three tested materials with no statistical difference. Regarding dentin bridge formation at group A, no significant differences was found between subgroups, while at group B, MTA subgroup exhibited significantly higher scores than other subgroups. In conclusion, addition of calcium hydroxide to Portland cement improves the dentin bridge formation qualitatively and quantitatively.
[Mh] Termos MeSH primário: Cimentos Dentários/farmacologia
Capeamento da Polpa Dentária/métodos
Agentes de Capeamento da Polpa Dentária e Pulpectomia/farmacologia
[Mh] Termos MeSH secundário: Animais
Modelos Animais de Doenças
Cães
Masculino
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Dental Cements); 0 (Pulp Capping and Pulpectomy Agents)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170321
[Lr] Data última revisão:
170321
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161218
[St] Status:MEDLINE


  10 / 1847 MEDLINE  
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[PMID]:27928102
[Au] Autor:Chen L; Suh BI
[Ad] Endereço:Department of Research and Development, Bisco Inc.
[Ti] Título:Cytotoxicity and biocompatibility of resin-free and resin-modified direct pulp capping materials: A state-of-the-art review.
[So] Source:Dent Mater J;36(1):1-7, 2017 Jan 31.
[Is] ISSN:1881-1361
[Cp] País de publicação:Japan
[La] Idioma:eng
[Ab] Resumo:Direct pulp capping is the placement of a dental material directly over exposed pulp to prevent dental pulp from dying and avoid the need for root canal treatments. Calcium hydroxide and calcium silicates/mineral trioxide aggregates (MTA) have been commonly used for direct pulp capping with great success clinically. In recent years, resin-modified calcium hydroxide and calcium silicates have been developed with the advantages of precise placement, command set, and superior physical strength. As pulp capping materials would be in direct contact with the pulp, the cytotoxicity and biocompatibility is of particular importance in order to avoid pulp irritation and maintain pulp vitality. Therefore, this review article will summarize the cytotoxicity and biocompatibility of direct pulp capping materials, particularly resin-modified materials.
[Mh] Termos MeSH primário: Capeamento da Polpa Dentária
Tratamento do Canal Radicular
[Mh] Termos MeSH secundário: Compostos de Alumínio
Compostos de Cálcio
Hidróxido de Cálcio
Polpa Dentária
Exposição da Polpa Dentária/terapia
Combinação de Medicamentos
Seres Humanos
Óxidos
Silicatos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Aluminum Compounds); 0 (Calcium Compounds); 0 (Drug Combinations); 0 (Oxides); 0 (Silicates); PF5DZW74VN (Calcium Hydroxide)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170823
[Lr] Data última revisão:
170823
[Sb] Subgrupo de revista:D
[Da] Data de entrada para processamento:161209
[St] Status:MEDLINE
[do] DOI:10.4012/dmj.2016-107



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BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde