[PMID]: | 27374450 |
[Au] Autor: | Huang L; Chen X; Li L |
[Ad] Endereço: | Xiangya Nursing School, Central South University, Changsha 410013; Department of Cardiology, Second Xiangya Hospital, Central South University, Changsha 410011, China. |
[Ti] Título: | Image and pathological features of Ewing's sarcoma in the oral and maxillofacial region. |
[So] Source: | Zhong Nan Da Xue Xue Bao Yi Xue Ban;41(6):637-43, 2016 Jun 28. |
[Is] ISSN: | 1672-7347 |
[Cp] País de publicação: | China |
[La] Idioma: | eng |
[Ab] Resumo: | OBJECTIVE: To systematically evaluate the image and pathological features of Ewing's sarcoma (ES) in the oral and maxillofacial region.
 METHODS: Eight patients with ES in the oral and maxillofacial region were enrolled for this study. The X-ray, computed tomography (CT), and magnetic resonance imaging (MRI) of ES and the pathological data were systematically evaluated.
 RESULTS: X-ray image showed a diffuse radiolucency with cystic component and ill-defined borders for bone lesion. CT showed that there was osteolytic mass with extensive bone destruction and soft tissue infiltration, but no periosteal reactions were observed. MRI demonstrated that ES showed an inhomogeneous structure and blurred borders with invasion to adjacent soft tissue for bone lesion. Similar manifestation also showed in MRI images for patients with soft tissues. Histologically, ES composed of small round cells, and expressed CD99, neuron specific enolase (NSE) and vimentin (Vim) in all patients. Desmin (Des), CD34, epithelial membrane antigen (EMA), chromogranin A (ChgA), etc, were negatively expressed in ES cells.
 CONCLUSION: X-ray, CT, and MRI are helpful to determine the property, extent and the relationship of ES with the surrounding tissues. Immunohistochemical stain of CD99, NSE, and Vim are helpful to confirm the pathological diagnosis of ES. |
[Mh] Termos MeSH primário: |
Boca Patologia Bucal Sarcoma de Ewing
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[Mh] Termos MeSH secundário: |
Seres Humanos Imagem por Ressonância Magnética Fosfopiruvato Hidratase Tomografia Computadorizada por Raios X
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[Pt] Tipo de publicação: | JOURNAL ARTICLE |
[Nm] Nome de substância:
| EC 4.2.1.11 (Phosphopyruvate Hydratase) |
[Em] Mês de entrada: | 1703 |
[Cu] Atualização por classe: | 170320 |
[Lr] Data última revisão:
| 170320 |
[Sb] Subgrupo de revista: | IM |
[Da] Data de entrada para processamento: | 160705 |
[St] Status: | MEDLINE |
[do] DOI: | 10.11817/j.issn.1672-7347.2016.06.014 |
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