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  1 / 4791 MEDLINE  
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[PMID]:29458673
[Au] Autor:Morse DJ; Wilson MJ; Wei X; Lewis MAO; Bradshaw DJ; Murdoch C; Williams DW
[Ad] Endereço:1​Oral and Biomedical Sciences, School of Dentistry, Cardiff University, Cardiff, UK.
[Ti] Título:Denture-associated biofilm infection in three-dimensional oral mucosal tissue models.
[So] Source:J Med Microbiol;67(3):364-375, 2018 Mar.
[Is] ISSN:1473-5644
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:PURPOSE: In vitro analyses of virulence, pathogenicity and associated host cell responses are important components in the study of biofilm infections. The Candida-related infection, denture-associated oral candidosis, affects up to 60 % of denture wearers and manifests as inflammation of palatal tissues contacting the denture-fitting surface. Commercially available three-dimensional tissue models can be used to study infection, but their use is limited for many academic research institutions, primarily because of the substantial purchase costs. The aim of this study was to develop and evaluate the use of in vitro tissue models to assess infections by biofilms on acrylic surfaces through tissue damage and Candida albicans virulence gene expression. METHODOLOGY: In vitro models were compared against commercially available tissue equivalents (keratinocyte-only, SkinEthic; full-thickness, MatTek Corporation). An in vitro keratinocyte-only tissue was produced using a cancer-derived cell line, TR146, and a full-thickness model incorporating primary fibroblasts and immortalised normal oral keratinocytes was also generated. The in vitro full-thickness tissues incorporated keratinocytes and fibroblasts, and have potential for future further development and analysis. RESULTS: Following polymicrobial infection with biofilms on acrylic surfaces, both in-house developed models were shown to provide equivalent results to the SkinEthic and MatTek models in terms of tissue damage: a significant (P<0.05) increase in LDH activity for mixed species biofilms compared to uninfected control, and no significant difference (P>0.05) in the expression of most C. albicans virulence genes when comparing tissue models of the same type. CONCLUSION: Our results confirm the feasibility and suitability of using these alternative in vitro tissue models for such analyses.
[Mh] Termos MeSH primário: Biofilmes/crescimento & desenvolvimento
Candidíase Bucal/microbiologia
Dentaduras/microbiologia
Interações Hospedeiro-Patógeno
Mucosa Bucal/microbiologia
[Mh] Termos MeSH secundário: Candida albicans/genética
Candida albicans/patogenicidade
Candida albicans/fisiologia
Linhagem Celular
Coinfecção/microbiologia
Fibroblastos/microbiologia
Seres Humanos
Queratinócitos/microbiologia
Polimetil Metacrilato
Estomatite sob Prótese
Virulência
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
9011-14-7 (Polymethyl Methacrylate)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180221
[St] Status:MEDLINE
[do] DOI:10.1099/jmm.0.000677


  2 / 4791 MEDLINE  
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[PMID]:29235572
[Au] Autor:Griffin JD
[Ti] Título:A Shared Understanding: Managing Aesthetic Treatment Imperfection.
[So] Source:Dent Today;36(3):90, 92, 94-5, 2017 Mar.
[Is] ISSN:8750-2186
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Prótese Parcial Fixa
Dentaduras
Estética Dentária
[Mh] Termos MeSH secundário: Adulto
Planejamento de Dentadura
Feminino
Gengivoplastia/métodos
Seres Humanos
Terapia a Laser
Maxila
Fotografia Dentária
Sorriso
Clareamento Dental
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180115
[Lr] Data última revisão:
180115
[Sb] Subgrupo de revista:D
[Da] Data de entrada para processamento:171214
[St] Status:MEDLINE


  3 / 4791 MEDLINE  
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[PMID]:28904706
[Au] Autor:Sadak N; Herrak L; Achachi L; El Ftouh M
[Ad] Endereço:Service de Pneumologie, CHU Ibn, Sina, Rabat, Maroc.
[Ti] Título:[When the denture becomes dangerous!]
[Ti] Título:Quand le dentier devient danger!.
[So] Source:Pan Afr Med J;27:179, 2017.
[Is] ISSN:1937-8688
[Cp] País de publicação:Uganda
[La] Idioma:fre
[Ab] Resumo:Although rare in adults, foreign body aspiration (FBA) is a serious accident which can be potentially life threatening or lead to significant sequelae. We report the case of a 50 year old patient without previous pathological history, presenting to the emergency department with chest pain, intermittent cough and exertional dyspnea occurring six days after the accidental aspiration of his plastic dental prosthesis during a meal. Clinical examination was unremarkable. Chest X-ray as well as abdominal x-ray requiring no prior preparation showed no abnormalities. Flexible bronchoscopy under general anesthesia showed FBA at the level of the intermediate trunk. Successful extraction was performed avoiding a much more invasive procedure. Standard X-ray can be useful to visualize radio-opaque FBA or indirect signs suggesting the presence of FBA, but diagnostic and therapeutic bronchoscopyis is essential.
[Mh] Termos MeSH primário: Broncoscopia/métodos
Dentaduras
Corpos Estranhos/diagnóstico
Aspiração Respiratória/diagnóstico
[Mh] Termos MeSH secundário: Tosse/etiologia
Dispneia/etiologia
Corpos Estranhos/complicações
Seres Humanos
Masculino
Meia-Idade
Radiografia Torácica
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170925
[Lr] Data última revisão:
170925
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170915
[St] Status:MEDLINE
[do] DOI:10.11604/pamj.2017.27.179.12902


  4 / 4791 MEDLINE  
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[PMID]:28877246
[Au] Autor:Patil S; Sarode SC; Sarode GS; Bhandi S; Awan KH; Ferrari M
[Ad] Endereço:Department of Medical Biotechnologies, School of Dental Medicine, University of Siena, Italy.
[Ti] Título:Prosthetic rehabilitation of oral submucous fibrosis patients: A systematic review of published case reports and case series.
[So] Source:PLoS One;12(9):e0184041, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Oral submucous fibrosis (OSF) is an insidious chronic condition characterized by restricted mouth opening. Prosthetic rehabilitation is challenging for OSF patients as obtaining a good impression requires adequate mouth opening. The aim of the present review is to systematically present the data from case reports published in the English-language literature. METHOD: A comprehensive search of the literature databases (PubMed, Medline, SCOPUS, Web of Science and Google Scholar) along with the references of published articles on prosthetic rehabilitation in OSF patients published to date was conducted. Keywords included a combination of 'Oral submucous fibrosis', 'prosthesis', 'dentures' and/or 'restricted mouth opening'. Citations from selected references and bibliographic linkages taken from similar cases were included in this review. The inclusion criteria selected for case reports on prosthetic rehabilitation in OSF patients, and cases of restricted mouth opening due to causes other than OSF were excluded from the study. RESULTS: A total of 21 cases were identified and analysed from 17 papers published in the English-language literature. Of these, 9 cases employed the sectional denture technique, 4 cases emphasized the need-based treatment approach in which conventional methods were modified, and 4 cases used mouth exercising devices. Finally, 1 case each involved, flexible denture, oral screen prosthesis, oral stents, surgery in conjunction with dentures. CONCLUSION: Prosthetic rehabilitation in OSF patients is a multifaceted approach and should be patient specific, although sectional dentures have achieved the best results.
[Mh] Termos MeSH primário: Dentaduras
Fibrose Oral Submucosa/reabilitação
[Mh] Termos MeSH secundário: Planejamento de Dentadura
Seres Humanos
Fibrose Oral Submucosa/terapia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171003
[Lr] Data última revisão:
171003
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170907
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0184041


  5 / 4791 MEDLINE  
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[PMID]:28678955
[Au] Autor:Queiroz CL; Bostock EM; Santos CF; Guimarães MA; Silva RHAD
[Ad] Endereço:Universidade de São Paulo, Faculdade de Odontologia de Ribeirão Preto, Departamento de Estomatologia, Saúde Coletiva e Odontologia Legal, Ribeirão Preto, SP, Brasil.
[Ti] Título:A forensic identification case and DPid - can it be a useful tool?
[So] Source:J Appl Oral Sci;25(3):346-353, 2017 May-Jun.
[Is] ISSN:1678-7765
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:Objective: The aim of this study was to show DPid as an important tool of potential application to solve cases with dental prosthesis, such as the forensic case reported, in which a skull, denture and dental records were received for analysis. Material and Methods: Human identification is still challenging in various circumstances and Dental Prosthetics Identification (DPid) stores the patient's name and prosthesis information and provides access through an embedded code in dental prosthesis or an identification card. All of this information is digitally stored on servers accessible only by dentists, laboratory technicians and patients with their own level of secure access. DPid provides a complete single-source list of all dental prosthesis features (materials and components) under complete and secure documentation used for clinical follow-up and for human identification. Results and Conclusion: If DPid tool was present in this forensic case, it could have been solved without requirement of DNA exam, which confirmed the dental comparison of antemortem and postmortem records, and concluded the case as a positive identification.
[Mh] Termos MeSH primário: Identificação da Prótese Dentária
Dentaduras/normas
Antropologia Forense/instrumentação
Antropologia Forense/métodos
Odontologia Legal/instrumentação
Odontologia Legal/métodos
[Mh] Termos MeSH secundário: Autopsia
Seres Humanos
Masculino
Reprodutibilidade dos Testes
Software
[Pt] Tipo de publicação:CASE REPORTS
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170912
[Lr] Data última revisão:
170912
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:170706
[St] Status:MEDLINE


  6 / 4791 MEDLINE  
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[PMID]:28442895
[Au] Autor:Klotz AL; Hassel AJ; Schröder J; Rammelsberg P; Zenthöfer A
[Ad] Endereço:Department of Prosthodontics, Dental School.
[Ti] Título:Oral health-related quality of life and prosthetic status of nursing home residents with or without dementia.
[So] Source:Clin Interv Aging;12:659-665, 2017.
[Is] ISSN:1178-1998
[Cp] País de publicação:New Zealand
[La] Idioma:eng
[Ab] Resumo:PURPOSE: The objective of this cross-sectional study was to evaluate the effect of prosthetic status on the oral health-related quality of life (OHRQoL) of nursing home residents with or without dementia. METHODS: The study was performed in 14 nursing homes across the federal state of Baden-Württemberg, Germany. All eligible participants were included, and general and medical information and information about their dental and prosthetic statuses were collected. The Geriatric Oral Health Assessment Index (GOHAI) was administered to evaluate OHRQoL. The Mini-Mental State Examination (MMSE) served to classify participants into living or not living with dementia according to the established cutoff value for dementia (MMSE <24). Parametric bivariate statistics and logistic regression models were used to analyze data at <0.05. RESULTS: A total of 169 participants were included in this study. The mean age of the participants was 82.9 years. A total of some 70% of the sample was living with dementia. The mean GOHAI score along the sample was 49.1 (8.3), and 41% of the sample reported substantially compromised OHRQoL (GOHAI <50). OHRQoL was statistically similar for people with or without dementia ( =0.234); objective oral health was also similar in both groups ( >0.05). The number of teeth (odds ratio [OR]: 2.0), the type of prosthetic status (OR: 6.5), and denture-related treatment needs (OR: 2.4) were the major factors significantly affecting OHRQoL ( <0.05). CONCLUSION: The OHRQoL of elderly nursing home residents is substantially compromised. Several prosthetic treatment needs for residents living with or without dementia were identified. Edentulism without tooth replacement and having <5 teeth resulted in an increased risk of substantially compromised OHRQoL. Further studies should be conducted to determine whether improvements in prosthetic status can increase OHRQoL.
[Mh] Termos MeSH primário: Demência/epidemiologia
Prótese Dentária/estatística & dados numéricos
Saúde Bucal/estatística & dados numéricos
Qualidade de Vida
[Mh] Termos MeSH secundário: Idoso
Idoso de 80 Anos ou mais
Estudos Transversais
Dentaduras/estatística & dados numéricos
Feminino
Avaliação Geriátrica
Alemanha
Instituição de Longa Permanência para Idosos
Seres Humanos
Masculino
Casas de Saúde
Perda de Dente/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171023
[Lr] Data última revisão:
171023
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170427
[St] Status:MEDLINE
[do] DOI:10.2147/CIA.S125128


  7 / 4791 MEDLINE  
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[PMID]:28288851
[Au] Autor:Cathcart SJ; Sofronescu AG
[Ad] Endereço:Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, United States.
[Ti] Título:Clinically distinct presentations of copper deficiency myeloneuropathy and cytopenias in a patient using excessive zinc-containing denture adhesive.
[So] Source:Clin Biochem;50(12):733-736, 2017 Aug.
[Is] ISSN:1873-2933
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: While copper deficiency has long been known to cause cytopenias, copper deficiency myeloneuropathy is a more recently described entity. Here, we present the case of two clinically distinct presentations of acquired copper deficiency syndromes secondary to excessive use of zinc-containing denture adhesive over five years: myeloneuropathy and severe macrocytic anemia and neutropenia. METHODS: Extensive laboratory testing and histologic evaluation of the liver and bone marrow, were necessary to rule out other disease processes and establish the diagnosis of copper deficiency. RESULTS: The initial presentation consisted of a myelopathy involving the posterior columns. Serum and urine copper were significantly decreased, and serum zinc was elevated. On second presentation (five years later), multiple hematological abnormalities were detected. Serum copper was again decreased, while serum zinc was elevated. CONCLUSIONS: Zinc overload is a preventable cause of copper deficiency syndromes. This rare entity presented herein highlights the importance of patient, as well as provider, education.
[Mh] Termos MeSH primário: Adrenoleucodistrofia/diagnóstico
Anemia Macrocítica/diagnóstico
Cobre/deficiência
Cimentos Dentários/efeitos adversos
Neutropenia/diagnóstico
Zinco/efeitos adversos
[Mh] Termos MeSH secundário: Adrenoleucodistrofia/etiologia
Adrenoleucodistrofia/patologia
Adulto
Anemia Macrocítica/etiologia
Anemia Macrocítica/patologia
Dentaduras
Feminino
Seres Humanos
Neutropenia/etiologia
Neutropenia/patologia
Síndrome
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Dental Cements); 789U1901C5 (Copper); J41CSQ7QDS (Zinc)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170717
[Lr] Data última revisão:
170717
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170315
[St] Status:MEDLINE


  8 / 4791 MEDLINE  
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[PMID]:28232977
[Au] Autor:Pires CW; Fraga S; Beck AC; Braun KO; Peres PE
[Ti] Título:Chemical Methods for Cleaning Conventional Dentures: What is the Best Antimicrobial Option? An In Vitro Study.
[So] Source:Oral Health Prev Dent;15(1):73-77, 2017.
[Is] ISSN:1602-1622
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:PURPOSE: To investigate the antimicrobial efficacy of different chemical agents used for denture cleaning. MATERIALS AND METHODS: Biofilm samples collected from 10 removable dentures were subjected to 10 disinfection protocols: distilled water for 30 min (negative control); 1% sodium hypochlorite for 10 min (positive control); diluted sodium hypochlorite for 10 min; vinegar for 20 min; 0.2% peracetic acid for 5 min; alkaline peroxide solution for 5 min; alkaline peroxide solution for 30 min; 0.12% chlorhexidine digluconate for 10 min; 0.05% sodium salicylate solution for 10 min; and enzymatic detergent for 2 min. Each of the samples was plated on petri dishes with Mueller-Hinton agar. The numbers of microbial colonies after 48 h at 37°C were compared using the Kruskal-Wallis and Dunn's tests (α = 0.05). RESULTS: Diluted sodium hypochlorite, vinegar, and chlorhexidine digluconate inhibited bacterial growth, with an effect similar to that of 1% sodium hypochlorite. The 0.2% peracetic acid and 0.05% sodium salicylate solutions were ineffective against bacterial growth, while enzymatic detergent and alkaline peroxide achieved an intermediate effect. CONCLUSION: Diluted sodium hypochlorite, vinegar, and chlorhexidine digluconate can be considered adequate products for cleaning dentures due to their potential for inhibiting bacterial growth, similar to 1% sodium hypochlorite. However, the effect of these chemical agents on acrylic resin (polymethylmethacrylate) denture base materials needs to be examined to provide complete information about their clinical indication.
[Mh] Termos MeSH primário: Anti-Infecciosos/farmacologia
Higienizadores de Dentadura/farmacologia
Dentaduras
[Mh] Termos MeSH secundário: Biofilmes/efeitos dos fármacos
Contagem de Colônia Microbiana
Dentaduras/microbiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Infective Agents); 0 (Denture Cleansers)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170713
[Lr] Data última revisão:
170713
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:170225
[St] Status:MEDLINE
[do] DOI:10.3290/j.ohpd.a37716


  9 / 4791 MEDLINE  
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[PMID]:28117852
[Au] Autor:Parisini P; Braccini L; Krejci I
[Ti] Título:A new veneer technique with prefabricated composite denture teeth combined with the "Biologically Oriented Preparation Technique" (BOPT) - a case report.
[So] Source:Int J Esthet Dent;12(1):14-26, 2017.
[Is] ISSN:2198-591X
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:This clinical report describes the step-by-step protocol for novel, 100% non-prep, custom-modified, prefabricated composite veneer restorations in the case of an esthetic rehabilitation of a patient presenting peg-shaped lateral incisors and undersized maxillary central incisors. A correct diagnosis, comprehensive treatment plan, and an interdisciplinary approach are necessary to obtain optimal conservative and predictable esthetic results.
[Mh] Termos MeSH primário: Porcelana Dentária
Facetas Dentárias
[Mh] Termos MeSH secundário: Adolescente
Dentaduras
Estética Dentária
Feminino
Seres Humanos
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
12001-21-7 (Dental Porcelain)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170526
[Lr] Data última revisão:
170526
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:170125
[St] Status:MEDLINE


  10 / 4791 MEDLINE  
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[PMID]:28032543
[Au] Autor:O'Donnell LE; Alalwan HK; Kean R; Calvert G; Nile CJ; Lappin DF; Robertson D; Williams C; Ramage G; Sherry L
[Ad] Endereço:1​Oral Sciences Research Group, Glasgow Dental School, School of Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, UK.
[Ti] Título:Candida albicans biofilm heterogeneity does not influence denture stomatitis but strongly influences denture cleansing capacity.
[So] Source:J Med Microbiol;66(1):54-60, 2017 Jan.
[Is] ISSN:1473-5644
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Approximately 20 % of the UK population wear some form of denture prosthesis, resulting in denture stomatitis in half of these individuals. Candida albicans is primarily attributed as the causative agent, due to its biofilm -forming ability. Recently, there has been increasing evidence of C. albicans biofilm heterogeneity and the negative impact it can have clinically; however, this phenomenon has yet to be studied in relation to denture isolates. The aims of this study were to evaluate C. albicans biofilm formation of clinical denture isolates in a denture environment and to assess antimicrobial activity of common denture cleansers against these tenacious communities. C. albicans isolated from dentures of healthy and diseased individuals was quantified using real-time PCR and biofilm biomass assessed using crystal violet. Biofilm development on the denture substratum poly(methyl methacrylate), Molloplast B and Ufi-gel was determined. Biofilm formation was assessed using metabolic and biomass stains, following treatment with denture hygiene products. Although C. albicans was detected in greater quantities in diseased individuals, it was not associated with increased biofilm biomass. Denture substrata were shown to influence biofilm biomass, with poly(methyl methacrylate) providing the most suitable environment for C. albicans to reside. Of all denture hygiene products tested, Milton had the most effective antimicrobial activity, reducing biofilm biomass and viability the greatest. Overall, our results highlight the complex nature of denture- related disease, and disease development cannot always be attributed to a sole cause. It is the distinct combination of various factors that ultimately determines the pathogenic outcome.
[Mh] Termos MeSH primário: Biofilmes
Candida albicans/crescimento & desenvolvimento
Higienizadores de Dentadura/farmacologia
Dentaduras/microbiologia
Estomatite sob Prótese/microbiologia
[Mh] Termos MeSH secundário: Antifúngicos/farmacologia
Candida albicans/efeitos dos fármacos
Estudos de Casos e Controles
Contagem de Colônia Microbiana
Seres Humanos
Viabilidade Microbiana/efeitos dos fármacos
Polimetil Metacrilato/química
Reação em Cadeia da Polimerase em Tempo Real
Propriedades de Superfície/efeitos dos fármacos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antifungal Agents); 0 (Denture Cleansers); 9011-14-7 (Polymethyl Methacrylate)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170320
[Lr] Data última revisão:
170320
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161230
[St] Status:MEDLINE
[do] DOI:10.1099/jmm.0.000419



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