Base de dados : MEDLINE
Pesquisa : E06.780.895 [Categoria DeCS]
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[PMID]:27307049
[Au] Autor:Sadaghiani L; Gleeson HB; Youde S; Waddington RJ; Lynch CD; Sloan AJ
[Ad] Endereço:Oral and Biomedical Sciences, School of Dentistry, College of Biomedical and Life Sciences, Cardiff University, Cardiff, UK sadaghianil@cf.ac.uk.
[Ti] Título:Growth Factor Liberation and DPSC Response Following Dentine Conditioning.
[So] Source:J Dent Res;95(11):1298-307, 2016 Oct.
[Is] ISSN:1544-0591
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Liberation of the sequestrated bioactive molecules from dentine by the action of applied dental materials has been proposed as an important mechanism in inducing a dentinogenic response in teeth with viable pulps. Although adhesive restorations and dentine-bonding procedures are routinely practiced, clinical protocols to improve pulp protection and dentine regeneration are not currently driven by biological knowledge. This study investigated the effect of dentine (powder and slice) conditioning by etchants/conditioners relevant to adhesive restorative systems on growth factor solubilization and odontoblast-like cell differentiation of human dental pulp progenitor cells (DPSCs). The agents included ethylenediaminetetraacetic acid (EDTA; 10%, pH 7.2), phosphoric acid (37%, pH <1), citric acid (10%, pH 1.5), and polyacrylic acid (25%, pH 3.9). Growth factors were detected in dentine matrix extracts drawn by EDTA, phosphoric acid, and citric acid from powdered dentine. The dentine matrix extracts were shown to be bioactive, capable of stimulating odontogenic/osteogenic differentiation as observed by gene expression and phenotypic changes in DPSCs cultured in monolayer on plastic. Polyacrylic acid failed to solubilize proteins from powdered dentine and was therefore considered ineffective in triggering a growth factor-mediated response in cells. The study went on to investigate the effect of conditioning dentine slices on growth factor liberation and DPSC behavior. Conditioning by EDTA, phosphoric acid, and citric acid exposed growth factors on dentine and triggered an upregulation in genes associated with mineralized differentiation, osteopontin, and alkaline phosphatase in DPSCs cultured on dentine. The cells demonstrated odontoblast-like appearances with elongated bodies and long extracellular processes extending on dentine surface. However, phosphoric acid-treated dentine appeared strikingly less populated with cells, suggesting a detrimental impact on cell attachment and growth when conditioning by this agent. These findings take crucial steps in informing clinical practice on dentine-conditioning protocols as far as treatment of operatively exposed dentine in teeth with vital pulps is concerned.
[Mh] Termos MeSH primário: Polpa Dentária/citologia
Dentina/fisiologia
Peptídeos e Proteínas de Sinalização Intercelular/metabolismo
Células-Tronco/efeitos dos fármacos
Condicionamento do Tecido (odontológico)
[Mh] Termos MeSH secundário: Resinas Acrílicas/farmacologia
Ácido Cítrico/farmacologia
Polpa Dentária/efeitos dos fármacos
Polpa Dentária/fisiologia
Dentina/efeitos dos fármacos
Ácido Edético/farmacologia
Expressão Gênica/efeitos dos fármacos
Seres Humanos
Ácidos Fosfóricos/farmacologia
Células-Tronco/citologia
Células-Tronco/fisiologia
Condicionamento do Tecido (odontológico)/efeitos adversos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Acrylic Resins); 0 (Intercellular Signaling Peptides and Proteins); 0 (Phosphoric Acids); 2968PHW8QP (Citric Acid); 4Q93RCW27E (carbopol 940); 9G34HU7RV0 (Edetic Acid); E4GA8884NN (phosphoric acid)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170922
[Lr] Data última revisão:
170922
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:160617
[St] Status:MEDLINE
[do] DOI:10.1177/0022034516653568


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[PMID]:27085676
[Au] Autor:Iqbal Z; Zafar MS
[Ad] Endereço:Department of Prosthodontics, FMH College of Dentistry, Lahore, Pakistan.
[Ti] Título:Role of antifungal medicaments added to tissue conditioners: A systematic review.
[So] Source:J Prosthodont Res;60(4):231-239, 2016 Oct.
[Is] ISSN:2212-4632
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:PURPOSE: The aim of this review is to investigate the current state of knowledge on the incorporation of antifungal agents into the tissue conditioners for the treatment of denture induced stomatitis. STUDY SELECTION: Studies reporting the incorporation of antifungal/antimicrobial agents in to tissue conditioners were included in the review. In order to search the studies on the topic "incorporation of antifungal agents in tissue conditioners for the treatment of denture induced stomatitis" ISI web of science, PubMed/MEDLINE, and Google-Scholar databases were searched from 1970 up to and including July 2015 using various keywords such as antifungal agents, tissue conditioners, Candida albicans, denture stomatitis, etc. RESULTS: Various studies reported the efficacy and effectiveness of adding conventional organic antifungal medicines (nystatin, azole group derivatives and chlorhexidine, antimicrobials/antifungals other than organic (silver zeolite, silver nano-particles, photo-catalysts and metallic oxides) and natural and herbal antimicrobials (tea tree oil, lemongrass essential oil and origanum oil) into various tissue conditioners. The review literature reported that incorporation of antifungal agents into tissue conditioners is effective with minimal or no effects on physical and mechanical properties of tissue conditioners. CONCLUSIONS: Incorporation of different antifungal medicaments to commercially available tissue conditioners can be recommended for the management of denture induced stomatitis.
[Mh] Termos MeSH primário: Anti-Infecciosos/administração & dosagem
Antifúngicos/administração & dosagem
Dentaduras/efeitos adversos
Estomatite sob Prótese/tratamento farmacológico
Estomatite sob Prótese/prevenção & controle
Condicionamento do Tecido (odontológico)
[Mh] Termos MeSH secundário: Candidíase Bucal
Bases de Dados Bibliográficas
Seres Humanos
Estomatite sob Prótese/etiologia
Estomatite sob Prótese/microbiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; META-ANALYSIS; REVIEW
[Nm] Nome de substância:
0 (Anti-Infective Agents); 0 (Antifungal Agents)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170728
[Lr] Data última revisão:
170728
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:160418
[St] Status:MEDLINE


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[PMID]:26415333
[Au] Autor:Ntounis A; Kamposiora P; Papavasiliou G; Divaris K; Zinelis S
[Ti] Título:Hardness Changes of Tissue Conditioners in Various Storage Media: An in Vitro Study.
[So] Source:Eur J Prosthodont Restor Dent;23(1):9-15, 2015 Mar.
[Is] ISSN:0965-7452
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The aim of the present study was to evaluate the effects of storage media on the longitudinal hardness changes of tissue conditioning materials. Four tissue-conditioning materials were used for fabrication of 80 disc-shaped specimens and divided in four groups, stored in four storage media. The specimens underwent artificial ageing corresponding to 30 nights of extra-oral storage. Hardness measurements were obtained at nine intervals between 8 and 240 hours after specimen fabrication. To test the effects of storage media on hardness we employed multivariate modelling (Bonferroni correction; α = 0.05). The materials exhibited varying hardness changes, most pronounced when stored in ambient air.
[Mh] Termos MeSH primário: Higienizadores de Dentadura/química
Reembasadores de Dentadura
Condicionamento do Tecido (odontológico)
[Mh] Termos MeSH secundário: Resinas Acrílicas
Ar
Materiais Biocompatíveis/química
Elastômeros/química
Dureza
Seres Humanos
Teste de Materiais
Metilmetacrilatos/química
Ácidos Ftálicos
Propriedades de Superfície
Temperatura Ambiente
Fatores de Tempo
Água/química
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Acrylic Resins); 0 (Biocompatible Materials); 0 (Denture Cleansers); 0 (Elastomers); 0 (Methylmethacrylates); 0 (Phthalic Acids); 0 (corega tabs); 059QF0KO0R (Water); 146883-70-7 (Coe Comfort); 9003-42-3 (poly(ethylmethacrylate))
[Em] Mês de entrada:1512
[Cu] Atualização por classe:150929
[Lr] Data última revisão:
150929
[Sb] Subgrupo de revista:D
[Da] Data de entrada para processamento:150930
[St] Status:MEDLINE


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[PMID]:26130235
[Au] Autor:Elkattah R; Kim JS; Londono J; Chiche G
[Ad] Endereço:Esthetic Fellow, Goldstein Center for Esthetic and Implant Dentistry, Department of Prosthodontics, College of Dental Medicine, Georgia Regents University, Augusta, Ga. Electronic address: remi.elkattah@gmail.com.
[Ti] Título:Fabricating short-term interim restorations from edentulous tissue conditioner material.
[So] Source:J Prosthet Dent;114(4):614-5, 2015 Oct.
[Is] ISSN:1097-6841
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Materiais Dentários/química
Restauração Dentária Temporária
Condicionamento do Tecido (odontológico)/métodos
[Mh] Termos MeSH secundário: Estética Dentária
Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Dental Materials)
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170124
[Lr] Data última revisão:
170124
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:150702
[St] Status:MEDLINE


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[PMID]:26067736
[Au] Autor:Hashem MI
[Ad] Endereço:Assistant Professor, Department of Dental Health, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia; Department of Dental Biomaterials, Al-Azhar University, Cairo Egypt, e-mail: codriyadh@gmail.com.
[Ti] Título:Advances in Soft Denture Liners: An Update.
[So] Source:J Contemp Dent Pract;16(4):314-8, 2015 04 01.
[Is] ISSN:1526-3711
[Cp] País de publicação:India
[La] Idioma:eng
[Ab] Resumo:Soft denture liners are used in complete and partial removable dentures to distribute functional loads homogeneously on the denture-bearing tissues. These materials are recommended in cases of irregular bone resorption, bony undercuts, thin atrophic mucosa, immediate prosthesis, healing after implant placement, and for patients with bruxism and xerostomia. The resilient lining materials can be categorized as plasticized acrylic resins or silicone elastomers. The plasticized acrylic resin comprises of acrylic polymers and copolymers, a liquid containing an acrylic monomer and plasticisers, such as ethyl alcohol and/or ethyl acetate responsible for preserving the material softness. The silicone elastomers, consisting of dimethylsiloxane polymers, with a chemical composition similar to that of the silicone impression materials devoid of leachable plasticisers, retain their elastic properties for prolonged periods. Most of the currently available materials have several disadvantages, including color stability, long-term resiliency, abrasion resistance, bond strength and porosity. Several modifications have been done recently to overcome of these disadvantages of the soft liners. The current review summarizes the recent developments in soft liners.
[Mh] Termos MeSH primário: Materiais Dentários/química
Reembasadores de Dentadura
[Mh] Termos MeSH secundário: Resinas Acrílicas/química
Anti-Infecciosos/química
Seres Humanos
Elastômeros de Silicone/química
Propriedades de Superfície
Condicionamento do Tecido (odontológico)/instrumentação
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Acrylic Resins); 0 (Anti-Infective Agents); 0 (Dental Materials); 0 (Silicone Elastomers)
[Em] Mês de entrada:1612
[Cu] Atualização por classe:170508
[Lr] Data última revisão:
170508
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:150613
[St] Status:MEDLINE


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Compagnoni, Marco Antonio
[PMID]:25906799
[Au] Autor:Toda C; Mendoza Marin DO; Rodriguez LS; Paleari AG; Pero AC; Compagnoni MA
[Ad] Endereço:Department of Dental Materials and Prosthodontics, Araraquara Dental School, UNESP-São Paulo State University, Araraquara, São Paulo, Brazil.
[Ti] Título:Antimicrobial activity of a tissue conditioner combined with a biocide polymer.
[So] Source:J Contemp Dent Pract;16(2):101-6, 2015 02 01.
[Is] ISSN:1526-3711
[Cp] País de publicação:India
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The characteristics of tissue conditioners support microorganism development that can threaten the health of the dentures user. PURPOSE: The object of this study was to evaluate the effect on antimicrobial activity, roughness and wettability surface of a tissue conditioners material combined with the antimicrobial polymer poly (2-tert-butilaminoethyl) methacrylate (PTBAEMA). MATERIALS AND METHODS: Specimens of tissue conditioner (Coe Soft(®)) were divided into three groups, according to the concentration of PTBAEMA incorporated (0, 10 and 25%). Antimicrobial activity was assessed by adherence assay of one of the microorganisms, Staphylococcus aureus, Streptococcus mutans and Candida albicans. Roughness measurements were made using a Mitutoyo SJ-400, and the mean arithmetic roughness values (Ra) obtained were used for the comparisons. The wettability properties were determined by contact angle measurements. RESULTS: The group containing 25% of PTBAEMA inhibited totally the S. aureus and S. mutans biofilm formation. A significant reduc tion in the S. aureus (Kruskal-Wallis, p = 0,001) and S. mutans (Kruscal-Wallis, p = 0,001) count for 10% PTBAEMA group compared with respective control group. No significant difference was found for C. albicans among PTBAEMA groups and control group (ANOVA, p > 0,05). Incorporating 10 and 25% PTBAEMA increased surface roughness and decreased contact angles (ANOVA and Tukey's post hoc tests, α = 5%). CONCLUSION: Incorporating 10% PTBAEMA into tissue conditioner increases wettability and roughness of tissue conditioner surface; and decreases the adhesion of S. mutans and S. aureus on material surface, but did not exhibit antimicrobial effect against C. albicans. SIGNIFICANCE: The PTBAEMA incorporated into tissue conditioner could prevent biofilm formation on elderly patient.
[Mh] Termos MeSH primário: Anti-Infecciosos/farmacologia
Materiais Dentários/química
Reembasadores de Dentadura
Metacrilatos/farmacologia
Condicionamento do Tecido (odontológico)/métodos
[Mh] Termos MeSH secundário: Aderência Bacteriana/efeitos dos fármacos
Biofilmes/efeitos dos fármacos
Candida albicans/efeitos dos fármacos
Seres Humanos
Teste de Materiais
Metacrilatos/química
Viabilidade Microbiana/efeitos dos fármacos
Staphylococcus aureus/efeitos dos fármacos
Streptococcus mutans/efeitos dos fármacos
Propriedades de Superfície
Molhabilidade
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Anti-Infective Agents); 0 (Dental Materials); 0 (Methacrylates); 0 (poly(2-(tert-butylamino)ethyl methacrylate)); 113979-46-7 (Coe-Soft denture lining material)
[Em] Mês de entrada:1609
[Cu] Atualização por classe:170508
[Lr] Data última revisão:
170508
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:150425
[St] Status:MEDLINE


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[PMID]:25694228
[Au] Autor:Fekrazad R; Lotfi G; Harandi M; Ayremlou S; Kalhori KA
[Ad] Endereço:Laser Research Center of Dentistry, Dental Faculty, Tehran University of Medical Sciences, Periodontal Department, Dental Faculty, AJA University of Medical Sciences, Tehran, Iran.
[Ti] Título:Evaluation of fibroblast attachment in root conditioning with Er, Cr:YSGG laser versus EDTA: a SEM study.
[So] Source:Microsc Res Tech;78(4):317-22, 2015 Apr.
[Is] ISSN:1097-0029
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The regeneration of periodontal support is a main concern in periodontal therapy. This study aims to investigate the efficacy of Er, Cr:YSGG laser and EDTA based conditioning in attachment of fibroblast on root surfaces. This in vitro study was conducted on 81 root plates (6 mm × 4 mm × 1 mm) prepared from 27 single-rooted human mature teeth. The samples were divided into three groups: (1) Er, Cr: YSGG laser conditioning with a G6 tip (2.78 µm, 0.75 W, pulse duration of 140 µs, repetition rate of 20 Hz) for 5-7 s; (2) EDTA conditioning (17%, pH: 8) for 1 min; and (3) the control group which were exposed neither to EDTA nor laser. The viability and proliferation rates assessments were performed using MTT assay on days 3 and 5. In addition, the level of cell attachment was studied using scanning electron microscopy. The data indicated Er, Cr:YSGG conditioning increased cell viability by lapse of time (from days 3-5), with significantly better cell attachment compared to the other groups on days 3 and 5 (P < 0.05). In addition, increasing cell attachment in the EDTA conditioning group compared with the control group was statistically significant on day 5 but not on day 3 (P < 0.05). In conclusion, Er, Cr:YSGG laser conditioning can promote enhance fibroblast attachment on dentinal root surfaces more than EDTA.
[Mh] Termos MeSH primário: Adesão Celular
Ácido Edético/metabolismo
Fibroblastos/fisiologia
Lasers de Estado Sólido
Preparo de Canal Radicular/métodos
Condicionamento do Tecido (odontológico)/métodos
[Mh] Termos MeSH secundário: Sobrevivência Celular
Formazans/análise
Seres Humanos
Microscopia Eletrônica de Varredura
Modelos Teóricos
Coloração e Rotulagem/métodos
Sais de Tetrazólio/análise
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Formazans); 0 (Tetrazolium Salts); 23305-68-2 (MTT formazan); 9G34HU7RV0 (Edetic Acid)
[Em] Mês de entrada:1512
[Cu] Atualização por classe:150326
[Lr] Data última revisão:
150326
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150220
[St] Status:MEDLINE
[do] DOI:10.1002/jemt.22477


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[PMID]:25302461
[Au] Autor:Belal MH; Watanabe H
[Ad] Endereço:1 Department of Oral Medicine, Periodontology & Oral Diagnosis, Faculty of Oral & Dental Medicine, Fayoum University , Bahaariy Region, Al-Fayoum, Egypt .
[Ti] Título:Comparative study on morphologic changes and cell attachment of periodontitis-affected root surfaces following conditioning with CO2 and Er:YAG laser irradiations.
[So] Source:Photomed Laser Surg;32(10):553-60, 2014 Oct.
[Is] ISSN:1557-8550
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: Clinical application of lasers in periodontal therapy has continued to expand in last decades; however there are still some controversies. The present study aimed to compare the conditioning effects of the carbon dioxide (CO2) or erbium-doped: yttrium, aluminum and garnet (Er:YAG) laser on periodontally diseased root surfaces following scaling and root planing (SRP) in terms of the alteration of morphologies as well as the attachment of periodontal ligament cells. METHODS: Forty-five periodontally affected root specimens were prepared and randomly assigned into three groups: I control (untreated diseased), II. SRP+CO2 laser (pulsed, noncontact mode), and III. SRP+Er:YAG laser (slight contact mode). After treatment, five specimens in each group were used for surface topographic examination. The remaining 10 specimens in each group were incubated with human periodontal ligament cell suspension. All the specimens were finally evaluated by scanning electron microscopy. RESULTS: The control specimens showed the lowest number of cultured cells, mostly in oval shape, with no tightly attached cells. The CO2 lased specimens showed a significant increase in the number of attached cells compared with controls, but demonstrated some major thermal alterations on the surfaces. The Er:YAG lased specimens showed the significantly highest number of attached cells, mostly in flat form, and did not show distinct thermal damage. CONCLUSIONS: The present study suggests that compared with the CO2 laser, the Er:YAG laser may constitute a more useful conditioning tool for enhancing periodontal cell attachment to periodontally diseased root surfaces, with fewer undesirable thermal side effects.
[Mh] Termos MeSH primário: Adesão Celular/efeitos da radiação
Terapia a Laser/métodos
Lasers de Gás
Lasers de Estado Sólido
Periodontite/radioterapia
Condicionamento do Tecido (odontológico)/métodos
Raiz Dentária/efeitos da radiação
[Mh] Termos MeSH secundário: Dióxido de Carbono
Raspagem Dentária
Seres Humanos
Técnicas In Vitro
Terapia a Laser/instrumentação
Microscopia Eletrônica de Varredura
Distribuição Aleatória
Propriedades de Superfície
Condicionamento do Tecido (odontológico)/instrumentação
Raiz Dentária/ultraestrutura
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Nome de substância:
142M471B3J (Carbon Dioxide)
[Em] Mês de entrada:1609
[Cu] Atualização por classe:141011
[Lr] Data última revisão:
141011
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:141011
[St] Status:MEDLINE
[do] DOI:10.1089/pho.2014.3769


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[PMID]:24393097
[Au] Autor:Sharma S; Hegde V
[Ad] Endereço:Senior Resident, Department of Prosthodontics, Maulana Azad Institute of Dental Sciences, New Delhi, India.
[Ti] Título:Comparative evaluation of antifungal activity of melaleuca oil and fluconazole when incorporated in tissue conditioner: an in vitro study.
[So] Source:J Prosthodont;23(5):367-73, 2014 Jul.
[Is] ISSN:1532-849X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PURPOSE: This in vitro study sought to compare the antifungal activity of melaleuca alternifolia oil and fluconazole mixed with a tissue conditioner. MATERIALS AND METHODS: By testing several concentrations of fluconazole and melaleuca oil in Visco-gel, the minimum most effective concentration of each antifungal agent against Candida albicans was determined. Mean inhibition diameter (MID) was used to measure the antifungal activity, and data were analyzed statistically for significance of findings. To determine the minimum most effective concentration of fluconazole, different concentrations of 1%, 3%, 5%, and 10% w/w in Visco-gel were tested on Sabouraud dextrose agar pregrown with C. albicans. MIDs were measured at 24 hours and on day 7, while carrying out the monitoring every day. Similarly, the minimum most effective concentration of melaleuca oil in Visco-gel was found by testing it in several concentrations (1%, 5%, 10%, 20%, 25%, 27.5%, 30%, 35% w/w). Subsequently, the minimum most effective concentration of each antifungal agent was used to compare the antifungal activity against C. albicans over 7 days using the same procedure and using plain tissue conditioner as the control. RESULT: The minimum most effective concentrations of melaleuca oil in Visco-gel and fluconazole in Visco-gel were 30% w/w and 5% w/w, respectively. Thirty percent w/w melaleuca oil was found to be the most effective (p < 0.001) and superior to 5% fluconazole in Visco-gel, as it retained substantial antifungal activity (MID), even on day 7 when fluconazole had lost its antifungal effect completely as evidenced by regrowth of C. albicans by day 7. CONCLUSION: Thirty percent melaleuca oil in tissue-conditioner Visco-gel was superior to 5% fluconazole in Visco-gel as an antifungal agent. Though both showed comparable antifungal activity at 24 hours against C. albicans, fluconazole had completely lost it by day 7, whereas melaleuca oil had substantially retained its antifungal action.
[Mh] Termos MeSH primário: Anti-Infecciosos Locais/farmacologia
Antifúngicos/farmacologia
Materiais Biocompatíveis/química
Fluconazol/farmacologia
Metilmetacrilatos/química
Óleo de Melaleuca/farmacologia
[Mh] Termos MeSH secundário: Anti-Infecciosos Locais/administração & dosagem
Antifúngicos/administração & dosagem
Candida albicans/efeitos dos fármacos
Fluconazol/administração & dosagem
Seres Humanos
Teste de Materiais
Melaleuca
Testes de Sensibilidade Microbiana
Micologia/métodos
Óleo de Melaleuca/administração & dosagem
Temperatura Ambiente
Fatores de Tempo
Condicionamento do Tecido (odontológico)
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Infective Agents, Local); 0 (Antifungal Agents); 0 (Biocompatible Materials); 0 (Methylmethacrylates); 68647-73-4 (Tea Tree Oil); 8VZV102JFY (Fluconazole); 9003-42-3 (poly(ethylmethacrylate))
[Em] Mês de entrada:1608
[Cu] Atualização por classe:140721
[Lr] Data última revisão:
140721
[Sb] Subgrupo de revista:D
[Da] Data de entrada para processamento:140108
[St] Status:MEDLINE
[do] DOI:10.1111/jopr.12117


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[PMID]:24079567
[Au] Autor:Srivatstava A; Ginjupalli K; Perampalli NU; Bhat N; Ballal M
[Ad] Endereço:Postgraduate student, Department of Dental Materials, Manipal College of Dental Sciences, Manipal University, Manipal, Karnataka, India.
[Ti] Título:Evaluation of the properties of a tissue conditioner containing origanum oil as an antifungal additive.
[So] Source:J Prosthet Dent;110(4):313-9, 2013 Oct.
[Is] ISSN:1097-6841
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:STATEMENT OF PROBLEM: Adherence and colonization of Candida albicans on tissue conditioners is common and results in irritation of the denture-bearing mucosa. PURPOSE: The purpose of this study was to investigate the antifungal activity and properties of a tissue conditioner by incorporating origanum oil. MATERIAL AND METHODS: Origanum oil at varying concentrations was incorporated into a poly(methyl methacrylate) based tissue conditioner (Visco-gel), and its antifungal activity against Candida albicans was evaluated at 1 day and 1 week by using the agar punch well method. The adherence of Candida albicans, surface roughness, tensile strength, and bond strength of the tissue conditioner with an optimized origanum oil concentration were evaluated. The data were subjected to 2-way ANOVA (α=.05). RESULTS: Sixty vol% origanum oil in tissue conditioner (Visco-gel) showed a mean inhibitory zone of 21.00 ± 1.58 mm at 1 day and 13.44 ± 0.88 mm at 1 week. The control group showed 90 ± 6.80 yeast cells/mm(2) at 1 day and 165 ± 7.63 yeast cells/mm(2) at 1 week, whereas the group with origanum oil showed 16 ± 1.15 yeast cells/mm(2) at 1 day and 32 ± 4.00 yeast cells/mm(2) at 1 week. Surface roughness was less with the incorporation of origanum oil. Tensile strength at 1 day was 0.91 ± 0.52 N for the control group, whereas the group with origanum oil showed 0.16 ± 0.05 N. At 1 day, the bond strength of 3.97 ± 0.75 MPa was observed with control specimens, whereas tissue conditioner with origanum oil showed a bond strength of 3.73 ± 0.65 MPa. CONCLUSIONS: Within the limitations of this in vitro study, origanum oil can be used as an additive to tissue conditioner to reduce the adherence of Candida albicans without significantly affecting its bond strength to heat-polymerized acrylic resin.
[Mh] Termos MeSH primário: Antifúngicos/uso terapêutico
Materiais Dentários/química
Reembasadores de Dentadura
Óleos Voláteis/uso terapêutico
Origanum
Condicionamento do Tecido (odontológico)/instrumentação
[Mh] Termos MeSH secundário: Resinas Acrílicas/química
Antifúngicos/química
Materiais Biocompatíveis/química
Candida albicans/efeitos dos fármacos
Colagem Dentária
Bases de Dentadura
Seres Humanos
Teste de Materiais
Metilmetacrilatos/química
Fenômenos Microbiológicos/efeitos dos fármacos
Óleos Voláteis/química
Propriedades de Superfície
Resistência à Tração
Fatores de Tempo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Acrylic Resins); 0 (Antifungal Agents); 0 (Biocompatible Materials); 0 (Dental Materials); 0 (Methylmethacrylates); 0 (Oils, Volatile); 39736Z7Q8W (origanum oil); 79933-29-2 (Trevalon universal); 9003-42-3 (poly(ethylmethacrylate))
[Em] Mês de entrada:1408
[Cu] Atualização por classe:161125
[Lr] Data última revisão:
161125
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:131002
[St] Status:MEDLINE



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