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[PMID]:28886101
[Au] Autor:Kayamba V; Shibemba A; Zyambo K; Heimburger DC; Morgan DR; Kelly P
[Ad] Endereço:Tropical Gastroenterology & Nutrition group, Department of Internal Medicine, University of Zambia School of Medicine, Lusaka, Zambia.
[Ti] Título:High prevalence of gastric intestinal metaplasia detected by confocal laser endomicroscopy in Zambian adults.
[So] Source:PLoS One;12(9):e0184272, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Confocal laser endomicroscopy (CLE) may increase the detection of gastric premalignant lesions, and facilitate targeted biopsies for histology. The study aim was to analyse premalignant lesions in Zambian adults using CLE. METHODS: Using CLE and histology we analysed the antral mucosa for gastric premalignant lesions in asymptomatic adults living with HIV and in HIV seronegative adults. Fasting gastric pH and the presence of Helicobacter pylori (H. pylori) were also evaluated. RESULTS: We enrolled 84 HIV seropositive participants (median age 43 years; 55 (65%) female), of whom 32 (38%) were anti-retroviral therapy (ART)-naïve. Also enrolled were 22 HIV seronegative controls (median age 39 years, 12 (55%) females). Hypochlorhydria was found in 48 (57%) HIV positive and 8 (38%) HIV negative controls (P = 0.14). Detection of gastric intestinal metaplasia (GIM) was higher (P = 0.007) using CLE (49, 54%) than histology (9, 9%) and, using CLE, GIM was similar between HIV positive (41, 60%) and negative groups (8, 36%; P = 0.08). Gastric luminal fluorescein leakage was significantly associated with the presence of GIM [OR 8.2; 95% CI 2.5-31, P<0.001]. CONCLUSION: CLE is useful for the detection of GIM, and luminal fluorescein leakage may represent a novel CLE marker for GIM. GIM is common in Zambian adults, and is highly prevalent irrespective of HIV infection or use of ART.
[Mh] Termos MeSH primário: Gastroenteropatias/epidemiologia
Gastroenteropatias/patologia
[Mh] Termos MeSH secundário: Acloridria/metabolismo
Adulto
Coinfecção
Endoscópios Gastrointestinais
Feminino
Mucosa Gástrica/metabolismo
Mucosa Gástrica/patologia
Gastrite Atrófica/complicações
Gastrite Atrófica/metabolismo
Gastrite Atrófica/patologia
Gastroenteropatias/diagnóstico
Infecções por HIV/complicações
Infecções por HIV/tratamento farmacológico
Infecções por HIV/virologia
Infecções por Helicobacter/complicações
Infecções por Helicobacter/microbiologia
Seres Humanos
Masculino
Metaplasia
Microscopia Confocal
Meia-Idade
Lesões Pré-Cancerosas/epidemiologia
Lesões Pré-Cancerosas/patologia
Prevalência
Neoplasias Gástricas/epidemiologia
Neoplasias Gástricas/etiologia
Neoplasias Gástricas/patologia
Adulto Jovem
Zâmbia/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171018
[Lr] Data última revisão:
171018
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170909
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0184272


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[PMID]:28216967
[Au] Autor:Law R; Varayil JE; WongKeeSong LM; Fidler J; Fletcher JG; Barlow J; Alexander J; Rajan E; Hansel S; Becker B; Larson JJ; Enders FT; Bruining DH; Coelho-Prabhu N
[Ad] Endereço:Ryan Law, Jithinraj E Varayil, Louis M WongKeeSong, Jeffrey Alexander, Elizabeth Rajan, Stephanie Hansel, Brenda Becker, David H Bruining, Nayantara Coelho-Prabhu, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN 55905, United States.
[Ti] Título:Assessment of multi-modality evaluations of obscure gastrointestinal bleeding.
[So] Source:World J Gastroenterol;23(4):614-621, 2017 Jan 28.
[Is] ISSN:2219-2840
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:AIM: To determine the frequency of bleeding source detection in patients with obscure gastrointestinal bleeding (OGIB) who underwent double balloon enteroscopy (DBE) after pre-procedure imaging [multiphase computed tomography enterography (MPCTE), video capsule endoscopy (VCE), or both] and assess the impact of imaging on DBE diagnostic yield. METHODS: Retrospective cohort study using a prospectively maintained database of all adult patients presenting with OGIB who underwent DBE from September 1 , 2002 to June 30 , 2013 at a single tertiary center. RESULTS: Four hundred and ninety five patients (52% females; median age 68 years) underwent DBE for OGIB. AVCE and/or MPCTE performed within 1 year prior to DBE (in 441 patients) increased the diagnostic yield of DBE (67.1% with preceding imaging 59.5% without). Using DBE as the gold standard, VCE and MPCTE had a diagnostic yield of 72.7% and 32.5% respectively. There were no increased odds of finding a bleeding site at DBE compared to VCE (OR = 1.3, = 0.150). There were increased odds of finding a bleeding site at DBE compared to MPCTE (OR = 5.9, < 0.001). In inpatients with overt OGIB, diagnostic yield of DBE was not affected by preceding imaging. CONCLUSION: DBE is a safe and well-tolerated procedure for the diagnosis and treatment of OGIB, with a diagnostic yield that may be increased after obtaining a preceding VCE or MPCTE. However, inpatients with active ongoing bleeding may benefit from proceeding directly to antegrade DBE.
[Mh] Termos MeSH primário: Endoscopia por Cápsula
Enteroscopia de Duplo Balão
Hemorragia Gastrointestinal/diagnóstico por imagem
Tomografia Computadorizada por Raios X
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Idoso de 80 Anos ou mais
Endoscópios Gastrointestinais
Feminino
Hemorragia Gastrointestinal/etiologia
Seres Humanos
Masculino
Meia-Idade
Imagem Multimodal
Reprodutibilidade dos Testes
Estudos Retrospectivos
Centros de Atenção Terciária
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170814
[Lr] Data última revisão:
170814
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170221
[St] Status:MEDLINE
[do] DOI:10.3748/wjg.v23.i4.614


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[PMID]:28208009
[Au] Autor:Tsutsumi K; Kato H; Okada H
[Ad] Endereço:Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan.
[Ti] Título:Impact of a Newly Developed Short Double-Balloon Enteroscope on Stent Placement in Patients with Surgically Altered Anatomies.
[So] Source:Gut Liver;11(2):306-311, 2017 Mar 15.
[Is] ISSN:2005-1212
[Cp] País de publicação:Korea (South)
[La] Idioma:eng
[Ab] Resumo:A newly developed short double-balloon enteroscope with a working channel enlarged to a diameter of 3.2 mm is a novel innovation in stent placement for patients with surgically altered anatomies. Herein, we report three patients in whom this new scope contributed to an efficient technique and ideal treatment. In the first case, the double guidewire technique was efficient and effective for multiple stent placements. In the second case, covered self-expandable metal stent (SEMS) placement, which is the standard treatment for malignant biliary obstruction, could be performed in a technologically sound and safe manner. In the third case, SEMS placement was performed as palliative treatment for malignant afferent-loop obstruction; this procedure could be performed soundly and safely using the through-the-scope technique. The wider working channel of this new scope also facilitates a smoother accessory insertion and high suction performance, which reduces procedure time and stress on endoscopists. Furthermore, this new scope, which has advanced force transmission, adaptive bending, and a smaller turning radius, is expected to be highly successful in both diagnosis and therapy for various digestive diseases in patients with surgically altered anatomies.
[Mh] Termos MeSH primário: Anormalidades do Sistema Digestório/cirurgia
Enteroscopia de Duplo Balão/instrumentação
Endoscópios Gastrointestinais
Implante de Prótese/instrumentação
Stents
[Mh] Termos MeSH secundário: Adulto
Idoso
Anormalidades do Sistema Digestório/etiologia
Enteroscopia de Duplo Balão/métodos
Desenho de Equipamento
Feminino
Seres Humanos
Masculino
Meia-Idade
Implante de Prótese/métodos
Resultado do Tratamento
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171011
[Lr] Data última revisão:
171011
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170217
[St] Status:MEDLINE
[do] DOI:10.5009/gnl16441


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[PMID]:28069113
[Au] Autor:Petersen BT; Cohen J; Hambrick RD; Buttar N; Greenwald DA; Buscaglia JM; Collins J; Eisen G; Reprocessing Guideline Task Force
[Ti] Título:Multisociety guideline on reprocessing flexible GI endoscopes: 2016 update.
[So] Source:Gastrointest Endosc;85(2):282-294.e1, 2017 Feb.
[Is] ISSN:1097-6779
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Desinfecção/normas
Endoscópios Gastrointestinais
Endoscopia do Sistema Digestório/instrumentação
Contaminação de Equipamentos/prevenção & controle
Reutilização de Equipamento/normas
Esterilização/normas
[Mh] Termos MeSH secundário: Endoscópios
Seres Humanos
Sociedades Médicas
[Pt] Tipo de publicação:JOURNAL ARTICLE; PRACTICE GUIDELINE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170918
[Lr] Data última revisão:
170918
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170111
[St] Status:MEDLINE


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[PMID]:27806411
[Au] Autor:Oette M; Wieland U; Schünemann M; Haes J; Reuter S; Jensen BE; Sagir A; Pfister H; Häussinger D
[Ad] Endereço:Clinic for General Medicine, Gastroenterology, and Infectious Diseases, Augustinerinnen Hospital, Cologne, Germany.
[Ti] Título:Anal chromoendoscopy using gastroenterological video-endoscopes: A new method to perform high resolution anoscopy for diagnosing intraepithelial neoplasia and anal carcinoma in HIV-infected patients.
[Ti] Título:Anale Chromoendoskopie mittels gastroenterologischer Video-Endoskopie: Eine neue Methode zur Durchführung der hochauflösenden Anoskopie in der Diagnostik der intraepithelialen Neoplasie und des Analkarzinoms bei HIV-infizierten Patienten..
[So] Source:Z Gastroenterol;55(1):23-31, 2017 Jan.
[Is] ISSN:1439-7803
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Anal carcinoma represents an increasing problem in HIV-infected patients. Anal intraepithelial neoplasia (AIN), the precursor lesion, is currently diagnosed by high-resolution anoscopy (HRA) using optical magnification derived from gynecological colposcopy. This prospective study evaluates anal chromoendoscopy (ACE) using standard gastroenterological video-endoscopes in diagnosing AIN. After clinical examination, proctoscopy and surface staining with acetic acid followed by Lugol's solution, ACE was performed with a mucosectomy cap on the tip of the endoscope. Biopsy specimens were collected from areas with a pathological staining pattern and from areas with normal appearance; combined results were considered as reference. Two hundred eleven HIV-positive patients seen between 2007 and 2013 were evaluated. Of these, 95.7 % were males, and the median age was 45 years. In 86.7 %, the mode of HIV transmission was sex among males. Combination antiretroviral treatment was applied in 75.8 %. The sensitivity of ACE in diagnosing AIN was 0.85, the specificity was 0.55, the positive predictive value was 0.50, and the negative predictive value (NPV) was 0.87. Diagnostic performance increased in individuals with high-grade lesions (NPV: 0.99) and in the second study period from 2011 to 2013. Side effects were rare and of minor clinical relevance. Anal chromoendoscopy is safe and effective in diagnosing AIN in a population of HIV-infected patients. It is particularly useful for the exclusion of high-grade lesions that have the strongest risk of progression to anal carcinoma. Therefore, ACE may become a valuable new tool to manage AIN and to prevent anal malignancy in HIV-positive patients.
[Mh] Termos MeSH primário: Neoplasias do Ânus/patologia
Carcinoma in Situ/patologia
Tecnologia de Fibra Óptica/instrumentação
Infecções por HIV/patologia
Gravação em Vídeo/instrumentação
[Mh] Termos MeSH secundário: Ácido Acético
Adulto
Idoso
Neoplasias do Ânus/etiologia
Corantes
Meios de Contraste
Endoscópios Gastrointestinais
Feminino
Infecções por HIV/complicações
Seres Humanos
Aumento da Imagem/instrumentação
Iodetos
Masculino
Meia-Idade
Estudos Prospectivos
Reprodutibilidade dos Testes
Sensibilidade e Especificidade
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Coloring Agents); 0 (Contrast Media); 0 (Iodides); Q40Q9N063P (Acetic Acid); T66M6Y3KSA (Lugol's solution)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171005
[Lr] Data última revisão:
171005
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161103
[St] Status:MEDLINE
[do] DOI:10.1055/s-0042-117646


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[PMID]:27931630
[Au] Autor:Kovaleva J
[Ad] Endereço:Centre for Medical Analysis, Oud-Strijderslaan 199, 2200 Herentals, Belgium. Electronic address: julia.kovaleva@live.nl.
[Ti] Título:Infectious complications in gastrointestinal endoscopy and their prevention.
[So] Source:Best Pract Res Clin Gastroenterol;30(5):689-704, 2016 Oct.
[Is] ISSN:1532-1916
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Gastrointestinal endoscopes are medical devices that have been associated with outbreaks of health care-associated infections. Because of the severity and limited treatment options of infections caused by multidrug-resistant Enterobacteriaceae and Pseudomonas aeruginosa, considerable attention has been paid to detection and prevention of these post-endoscopic outbreaks. Endoscope reprocessing involves cleaning, high-level disinfection/sterilization followed by rinsing and drying before storage. Failure of the decontamination process implies the risk of settlement of biofilm producing species in endoscope channels. This review covers the infectious complications in gastrointestinal endoscopy and their prevention and highlights the problem of infection risk associated with different steps of endoscope reprocessing.
[Mh] Termos MeSH primário: Infecção Hospitalar/etiologia
Infecção Hospitalar/prevenção & controle
Desinfecção/métodos
Endoscópios Gastrointestinais/microbiologia
Endoscopia Gastrointestinal/efeitos adversos
[Mh] Termos MeSH secundário: Biofilmes
Endoscópios Gastrointestinais/efeitos adversos
Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170107
[Lr] Data última revisão:
170107
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161210
[St] Status:MEDLINE


  7 / 1620 MEDLINE  
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[PMID]:27922516
[Au] Autor:Shellnutt C
[Ad] Endereço:Cathleen Shellnutt, MSN, APRN, AGCNS-BC, CGRN, is Complex GI Advanced Practice Nurse, The Medical Center of Plano, Texas.
[Ti] Título:Advances in Endoscope Reprocessing Technology and Its Impact on Pathogen Transmission.
[So] Source:Gastroenterol Nurs;39(6):457-465, 2016 Nov/Dec.
[Is] ISSN:1538-9766
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Pathogen transmissions via flexible endoscopes have been documented in the literature and have been historically related to human error or omission of steps in the reprocessing cycle. The 2008 Centers for Disease Control and Prevention report challenged manufacturers of automated endoscope reprocessors to improve and advance technology to automate more of the reprocessing steps. A review and synthesis of the literature following the 2008 Centers for Disease Control and Prevention report was performed to evaluate whether advances in reprocessing technology have occurred and whether these have had an impact on pathogen transmission via flexible endoscopes. The Iowa Model of Evidence-Based Practice to Promote Quality Care was used to guide the project. The literature search regarding pathogen transmission related to flexible endoscopes yielded 10 documents citing infections from 2008 to 2015. A total of 353 patients were identified as having been infected with a contaminated gastroscope, bronchoscope, or duodenoscope. An evaluation of reprocessing technology identified 3 automated endoscope reprocessors with enhanced capabilities and flushing devices intended to automate portions of the manual cleaning step.
[Mh] Termos MeSH primário: Endoscópios Gastrointestinais/microbiologia
Endoscopia Gastrointestinal/instrumentação
Contaminação de Equipamentos/prevenção & controle
Reutilização de Equipamento/normas
Guias de Prática Clínica como Assunto
[Mh] Termos MeSH secundário: Tecnologia Biomédica
Centers for Disease Control and Prevention (U.S.)
Infecção Hospitalar/prevenção & controle
Endoscopia Gastrointestinal/efeitos adversos
Medicina Baseada em Evidências
Feminino
Seres Humanos
Masculino
Controle de Qualidade
Estados Unidos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170615
[Lr] Data última revisão:
170615
[Sb] Subgrupo de revista:N
[Da] Data de entrada para processamento:161207
[St] Status:MEDLINE


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[PMID]:27895403
[Au] Autor:Richter-Schrag HJ; Glatz T; Walker C; Fischer A; Thimme R
[Ad] Endereço:Hans-Jürgen Richter-Schrag, Christine Walker, Andreas Fischer, Robert Thimme, Center of Interdisciplinary Gastrointestinal Endoscopy, Department of Medicine II, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, D-79106 Freiburg, Germany.
[Ti] Título:First-line endoscopic treatment with over-the-scope clips significantly improves the primary failure and rebleeding rates in high-risk gastrointestinal bleeding: A single-center experience with 100 cases.
[So] Source:World J Gastroenterol;22(41):9162-9171, 2016 Nov 07.
[Is] ISSN:2219-2840
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:AIM: To evaluate rebleeding, primary failure (PF) and mortality of patients in whom over-the-scope clips (OTSCs) were used as first-line and second-line endoscopic treatment (FLET, SLET) of upper and lower gastrointestinal bleeding (UGIB, LGIB). METHODS: A retrospective analysis of a prospectively collected database identified all patients with UGIB and LGIB in a tertiary endoscopic referral center of the University of Freiburg, Germany, from 04-2012 to 05-2016 ( = 93) who underwent FLET and SLET with OTSCs. The complete Rockall risk scores were calculated from patients with UGIB. The scores were categorized as < or ≥ 7 and were compared with the original Rockall data. Differences between FLET and SLET were calculated. Univariate and multivariate analysis were performed to evaluate the factors that influenced rebleeding after OTSC placement. RESULTS: Primary hemostasis and clinical success of bleeding lesions (without rebleeding) was achieved in 88/100 (88%) and 78/100 (78%), respectively. PF was significantly lower when OTSCs were applied as FLET compared to SLET (4.9% 23%, = 0.008). In multivariate analysis, patients who had OTSC placement as SLET had a significantly higher rebleeding risk compared to those who had FLET (OR 5.3; = 0.008). Patients with Rockall risk scores ≥ 7 had a significantly higher in-hospital mortality compared to those with scores < 7 (35% 10%, = 0.034). No significant differences were observed in patients with scores < or ≥ 7 in rebleeding and rebleeding-associated mortality. CONCLUSION: Our data show for the first time that FLET with OTSC might be the best predictor to successfully prevent rebleeding of gastrointestinal bleeding compared to SLET. The type of treatment determines the success of primary hemostasis or primary failure.
[Mh] Termos MeSH primário: Endoscópios Gastrointestinais
Hemorragia Gastrointestinal/cirurgia
Hemostase Endoscópica/instrumentação
[Mh] Termos MeSH secundário: Adulto
Idoso
Idoso de 80 Anos ou mais
Distribuição de Qui-Quadrado
Bases de Dados Factuais
Desenho de Equipamento
Feminino
Hemorragia Gastrointestinal/diagnóstico
Hemorragia Gastrointestinal/mortalidade
Alemanha
Hemostase Endoscópica/efeitos adversos
Hemostase Endoscópica/mortalidade
Mortalidade Hospitalar
Seres Humanos
Modelos Logísticos
Masculino
Meia-Idade
Análise Multivariada
Razão de Chances
Recidiva
Estudos Retrospectivos
Fatores de Risco
Falha de Tratamento
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; OBSERVATIONAL STUDY
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170424
[Lr] Data última revisão:
170424
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161130
[St] Status:MEDLINE


  9 / 1620 MEDLINE  
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[PMID]:27796141
[Au] Autor:Xia HT; Liang B; Liu Y; Yang T; Zeng JP; Dong JH
[Ad] Endereço:a Hospital and Institute of Hepatobiliary Surgery , Chinese PLA General Hospital, Chinese PLA Medical School , Beijing , China.
[Ti] Título:Ultrathin choledochoscope improves outcomes in the treatment of gallstones and suspected choledocholithiasis.
[So] Source:Expert Rev Gastroenterol Hepatol;10(12):1409-1413, 2016 Dec.
[Is] ISSN:1747-4132
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: We aimed to compare laparoscopic cholecystectomy (LC) and simultaneous laparoscopic transcystic common bile duct exploration (LTCBDE) using an ultrathin choledochoscope with LC followed by endoscopic retrograde cholangiopancreatography (ERC) and endoscopic sphincterotomy (ES) when indicated. METHODS: We retrospectively reviewed the records of patients seen between 2004 and 2014 and treated with LC+LTCBDE or LC for gallstones and suspected choledocholithiasis. Postoperative complications and surgical outcomes were compared using t-test, Mann-Whitney U test, or chi-square test. RESULTS: 115 patients underwent successful LC+LTCBDE and 112 LC; follow-up data was available for 103 and 106 patients, respectively. Seventeen patients (16.5%) in the LC+LTCBDE group and 10 (28.6%) in the LC+ERC+ES group developed complications (P = 0.114). The LC+LTCBDE group had a significantly higher rate of satisfactory biliary function outcomes than the LC+ERC+ES group (98.1% vs. 85.7%, respectively) (P = 0.017). CONCLUSIONS: Single-step LC+LTCBDE using an ultrathin choledochoscope may provide better outcomes in patients with gallstones and suspected choledocholithiasis.
[Mh] Termos MeSH primário: Colangiopancreatografia Retrógrada Endoscópica
Colecistectomia Laparoscópica/instrumentação
Coledocolitíase/cirurgia
Endoscópios Gastrointestinais
Cálculos Biliares/cirurgia
Esfinterotomia Endoscópica
[Mh] Termos MeSH secundário: Adulto
Distribuição de Qui-Quadrado
Colangiopancreatografia Retrógrada Endoscópica/efeitos adversos
Colecistectomia Laparoscópica/efeitos adversos
Coledocolitíase/diagnóstico por imagem
Desenho de Equipamento
Feminino
Cálculos Biliares/diagnóstico por imagem
Seres Humanos
Masculino
Meia-Idade
Complicações Pós-Operatórias/etiologia
Estudos Retrospectivos
Fatores de Risco
Esfinterotomia Endoscópica/efeitos adversos
Resultado do Tratamento
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170417
[Lr] Data última revisão:
170417
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161101
[St] Status:MEDLINE


  10 / 1620 MEDLINE  
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[PMID]:27756062
[Au] Autor:Kikuchi D; Iizuka T; Yamada A; Nomura K; Kuribayashi Y; Kimura R; Hoteya S; Kaise M
[Ad] Endereço:Department of Gastroenterology, Toranomon Hospital, Tokyo, Japan.
[Ti] Título:Feasibility of a Newly Developed Thumb Control Device for Simultaneous Manipulation of the Endoscope and Treatment Devices in Endoscopic Submucosal Dissection: A Clinical Feasibility Study.
[So] Source:Digestion;94(3):123-128, 2016.
[Is] ISSN:1421-9867
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:BACKGROUND/AIM: We developed a new device for the simultaneous manipulation of an endoscope and treatment devices, which we named the Smart Shooter®. The aim of this study was to validate the feasibility of using the Smart Shooter® in endoscopic submucosal dissection (ESD). METHODS: This pilot feasibility study conducted between March and June 2014 involved 20 consecutive patients who underwent ESD for superficial gastrointestinal neoplasia. The primary endpoint was a serious adverse event during the ESD procedure. The secondary endpoints were completion rate of ESD using the Smart Shooter® and a mechanical problem with the Smart Shooter® during ESD. RESULTS: A total of 20 patients underwent ESD for 23 lesions: 5 pharyngeal, 8 esophageal, 7 gastric, and 3 colonic lesions. There were no serious adverse events or mechanical problems during ESD. The completion rate of ESD using the Smart Shooter® was 82.6% (19/23). CONCLUSION: ESD using the Smart Shooter® appears to be technically feasible. CLINICAL TRIAL REGISTRATION: UMIN 000013710.
[Mh] Termos MeSH primário: Endoscópios Gastrointestinais
Ressecção Endoscópica de Mucosa/instrumentação
Endoscopia Gastrointestinal/instrumentação
Neoplasias Gastrointestinais/cirurgia
[Mh] Termos MeSH secundário: Idoso
Idoso de 80 Anos ou mais
Ressecção Endoscópica de Mucosa/efeitos adversos
Endoscopia Gastrointestinal/efeitos adversos
Estudos de Viabilidade
Feminino
Neoplasias Gastrointestinais/patologia
Seres Humanos
Japão
Masculino
Meia-Idade
Projetos Piloto
Resultado do Tratamento
[Pt] Tipo de publicação:CLINICAL TRIAL; JOURNAL ARTICLE
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170330
[Lr] Data última revisão:
170330
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161019
[St] Status:MEDLINE
[do] DOI:10.1159/000450703



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