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[PMID]:28826552
[Au] Autor:Kopylov U; Yung DE; Koulaouzidis A; Eliakim R
[Ad] Endereço:Department of Gastroenterology, Sheba Medical Center, Ramat Gan, Israel; Sackler Medical School, Tel Aviv University, Tel Aviv, Israel.
[Ti] Título:Retention rate in small-bowel capsule endoscopy.
[So] Source:Gastrointest Endosc;86(3):573, 2017 09.
[Is] ISSN:1097-6779
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Endoscopia por Cápsula
Intestino Delgado
[Mh] Termos MeSH secundário: Cápsulas Endoscópicas
Seres Humanos
[Pt] Tipo de publicação:LETTER; COMMENT
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171031
[Lr] Data última revisão:
171031
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170823
[St] Status:MEDLINE


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[PMID]:28253209
[Au] Autor:Yung DE; Plevris JN; Koulaouzidis A
[Ad] Endereço:Centre for Liver and Digestive Disorders, The Royal Infirmary of Edinburgh, Edinburgh, Scotland, UK.
[Ti] Título:Short article: Aspiration of capsule endoscopes: a comprehensive review of the existing literature.
[So] Source:Eur J Gastroenterol Hepatol;29(4):428-434, 2017 Apr.
[Is] ISSN:1473-5687
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: Capsule endoscopy (CE) has an excellent safety profile. Although retention is the most cited complication, capsule aspiration is less frequent and is often reported only as isolated cases. This study represents a systematic effort to compile and scrutinize the available data on capsule aspiration to provide comprehensive and conclusive information on this CE complication. MATERIALS AND METHODS: A systematic literature search was performed in PubMed, Embase and Chinese National Knowledge Infrastructure. The search terms used were 'capsule endoscopy' AND 'aspiration' (both terms searched as keyword and MeSH). We included case reports and/or series on capsule aspiration, as well as observational cohort studies that reported capsule aspiration among their complications/outcomes. RESULTS: Thirty-four case reports with 37 cases of capsule aspiration were identified. A further four observational studies reported aspiration as part of a cohort of patients undergoing CE. 94.6% of aspirations occurred in elderly men. 87.1% had significant comorbidities. 59.5% had symptoms on aspiration, with cough reported most frequently. The most common location of aspiration was the right main bronchus. Half of the patients required intervention for capsule retrieval; bronchoscopy was the most common management, with good effect. There was a single fatality following capsule aspiration, not directly related to the procedure, and one case of aspiration pneumonia. Outcomes were good for all other patients. The estimated overall aspiration rate is 0.1%. CONCLUSION: Although very rare and generally safely managed, capsule aspiration should be anticipated in certain patient groups and capsule administration should be approached with necessary precautions.
[Mh] Termos MeSH primário: Cápsulas Endoscópicas/efeitos adversos
Endoscopia por Cápsula/efeitos adversos
Corpos Estranhos/etiologia
Pulmão
Aspiração Respiratória/etiologia
[Mh] Termos MeSH secundário: Broncoscopia/métodos
Tosse/etiologia
Corpos Estranhos/terapia
Seres Humanos
Aspiração Respiratória/terapia
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170918
[Lr] Data última revisão:
170918
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170303
[St] Status:MEDLINE
[do] DOI:10.1097/MEG.0000000000000821


  3 / 481 MEDLINE  
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[PMID]:28103201
[Au] Autor:Chitul A; Voiosu AM; Marinescu M; Caraiola S; Nicolau A; Badea GC; Pârvu MI; Ionescu RA; Mateescu BR; Voiosu MR; Baicus CR; Rimbas M
[Ti] Título:Different effects of anti-TNF-alpha biologic drugs on the small bowel macroscopic inflammation in patients with ankylosing spondylitis.
[So] Source:Rom J Intern Med;55(1):44-52, 2017 Mar 01.
[Is] ISSN:1220-4749
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:BACKGROUND & AIMS: Considering the ability of anti-TNF alpha drugs to lower the burden intestinal inflammation in patients with inflammatory bowel disease (IBD), and the similarity between IBD and ankylosing spondylitis (AS) regarding inflammatory intestinal involvement, we aimed to investigate the impact of anti-TNF alpha biologic therapy on subclinical intestinal inflammation in AS patients. METHODS: Between January 2008 and December 2013, 38 AS patients and 23 controls were enrolled in the study and investigated with small bowel videocapsule endoscopy examination and ileocolonoscopy. Each tertile of the small bowel (proximal, mid and distal) was assessed by calculating the Lewis score based on the image stream. RESULTS: The Lewis scores were significantly higher in the AS group compared to controls (580.9 ± 818 vs. 81 ± 121, p<0.001). 16 patients (42.1%) were on anti-TNF alpha therapy (Adalimumab (n = 5), Infliximab (n = 5) or Etanercept (n = 6)).31.3% of them used NSAIDs simultaneously, compared with 77.3% of the other patients (p<0.01). Their Lewis scores were lower compared to the other patients for the entire small bowel (306 ± 164 vs. 790 ± 1038, p = 0.015), its proximal and distal tertiles (238 ± 154 vs. 560 ± 543, p = 0.021, and 140 ± 189 vs. 300 ± 220, p = 0.027, respectively). The Lewis score was also lower in patients receiving Adalimumab/Infliximab compared to those on Etanercept for the entire bowel and its distal tertile (262 ± 165 vs. 380 ± 148, p = 0.069 and 62 ± 101 vs. 273 ± 236, p = 0.060, respectively). CONCLUSION: Anti-TNF alpha therapy in patients with AS reduces the subclinical intestinal inflammation, but the magnitude seems to depend upon the class anti-TNF alpha agent used (Clinical Trials. gov NCT00768950).
[Mh] Termos MeSH primário: Antirreumáticos/uso terapêutico
Fármacos Gastrointestinais/uso terapêutico
Doenças Inflamatórias Intestinais/tratamento farmacológico
Mucosa Intestinal/patologia
Espondilite Anquilosante/tratamento farmacológico
Fator de Necrose Tumoral alfa/antagonistas & inibidores
[Mh] Termos MeSH secundário: Adalimumab/administração & dosagem
Adulto
Anti-Inflamatórios não Esteroides/administração & dosagem
Cápsulas Endoscópicas
Colonoscopia/métodos
Quimioterapia Combinada
Etanercepte/administração & dosagem
Feminino
Hospitais Universitários
Seres Humanos
Doenças Inflamatórias Intestinais/complicações
Doenças Inflamatórias Intestinais/diagnóstico
Infliximab/administração & dosagem
Masculino
Meia-Idade
Estudos Prospectivos
Índice de Gravidade de Doença
Espondilite Anquilosante/complicações
Espondilite Anquilosante/diagnóstico
Resultado do Tratamento
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; OBSERVATIONAL STUDY
[Nm] Nome de substância:
0 (Anti-Inflammatory Agents, Non-Steroidal); 0 (Antirheumatic Agents); 0 (Gastrointestinal Agents); 0 (Tumor Necrosis Factor-alpha); B72HH48FLU (Infliximab); FYS6T7F842 (Adalimumab); OP401G7OJC (Etanercept)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170707
[Lr] Data última revisão:
170707
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170120
[St] Status:MEDLINE


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[PMID]:28084581
[Au] Autor:Muguruma N; Tanaka K; Teramae S; Takayama T
[Ad] Endereço:Department of Gastroenterology and Oncology, Tokushima University Graduate School of Biomedical Sciences, 3-18-15 Kuramoto-cho, Tokushima, 770-8503, Japan. muguruma.clin.med@gmail.com.
[Ti] Título:Colon capsule endoscopy: toward the future.
[So] Source:Clin J Gastroenterol;10(1):1-6, 2017 Feb.
[Is] ISSN:1865-7265
[Cp] País de publicação:Japan
[La] Idioma:eng
[Ab] Resumo:Colon capsule endoscopy is a wireless and minimally invasive technique for visualization of the whole colon. With recent improvements of technical features in second-generation systems, a more important role for colon capsule endoscopy is rapidly emerging. Although several limitations and drawbacks are yet to be resolved, its usefulness as a tool for colorectal cancer screening and monitoring disease activity in inflammatory bowel diseases has become more apparent with increased use. Further investigations, including multicenter trials, are required to evaluate the substantial role of the colon capsule in managing colorectal diseases.
[Mh] Termos MeSH primário: Endoscopia por Cápsula/tendências
Doenças do Colo/diagnóstico
[Mh] Termos MeSH secundário: Cápsulas Endoscópicas/tendências
Endoscopia por Cápsula/efeitos adversos
Endoscopia por Cápsula/métodos
Pólipos do Colo/diagnóstico
Colonoscopia/efeitos adversos
Colonoscopia/métodos
Colonoscopia/tendências
Neoplasias Colorretais/diagnóstico
Contraindicações
Detecção Precoce de Câncer/métodos
Desenho de Equipamento/tendências
Seres Humanos
Doenças Inflamatórias Intestinais/diagnóstico
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1702
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170114
[St] Status:MEDLINE
[do] DOI:10.1007/s12328-016-0710-3


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[PMID]:28056462
[Au] Autor:Buscot M; Leroy S; Pradelli J; Chaabane N; Hebuterne X; Marquette CH; Filippi J
[Ad] Endereço:Service de Pneumologie, Centre Hospitalier Universitaire, Université Nice Sophia Antipolis, Nice, France.
[Ti] Título:Bronchial Aspiration of Capsule Endoscope.
[So] Source:Respiration;93(2):122-125, 2017.
[Is] ISSN:1423-0356
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:Capsule endoscope aspiration is an increasingly reported complication, potentially responsible for respiratory distress and asphyxia. This adverse event is primarily managed by rigid bronchoscopy when spontaneous expulsion does not occur. This complication is all the more detrimental to patients as it can delay or jeopardize further digestive exploration. We report direct repositioning of the capsule in the stomach at the same time as bronchoscopy, thus making second-line gastrointestinal endoscopy needless.
[Mh] Termos MeSH primário: Asfixia/cirurgia
Brônquios/cirurgia
Broncoscopia/métodos
Cápsulas Endoscópicas
Corpos Estranhos/cirurgia
Aspiração Respiratória/cirurgia
[Mh] Termos MeSH secundário: Idoso
Asfixia/diagnóstico
Asfixia/etiologia
Seres Humanos
Masculino
Radiografia Torácica
Aspiração Respiratória/complicações
Aspiração Respiratória/diagnóstico
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; VIDEO-AUDIO MEDIA
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170919
[Lr] Data última revisão:
170919
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170106
[St] Status:MEDLINE
[do] DOI:10.1159/000453587


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[PMID]:27908514
[Au] Autor:Barkin JA; Barkin JS
[Ad] Endereço:Division of Gastroenterology, Department of Medicine, Leonard M. Miller School of Medicine, University of Miami, 1120 North West 14th Street, Clinical Research Building, Suite 1116 (D-49), Miami, FL 33136, USA. Electronic address: jabarkin@med.miami.edu.
[Ti] Título:Video Capsule Endoscopy: Technology, Reading, and Troubleshooting.
[So] Source:Gastrointest Endosc Clin N Am;27(1):15-27, 2017 Jan.
[Is] ISSN:1558-1950
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Video capsule endoscopy (VCE) has completed the endoscopic visualization of the entire luminal gastrointestinal tract. VCE can be performed in inpatients and outpatients, requires appropriate bowel preparation before the study, and can be administered via oral swallowing or endoscopic device placement into the small bowel based on outlined patient-dependent factors. Current commercially available VCE systems were reviewed and compared for individual features and attributes. This article focuses on preparation for VCE, currently available VCE technology, how to read a VCE study, and risks and contraindications to VCE.
[Mh] Termos MeSH primário: Cápsulas Endoscópicas
Endoscopia por Cápsula
Trato Gastrointestinal
[Mh] Termos MeSH secundário: Seres Humanos
Intestino Delgado/diagnóstico por imagem
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170608
[Lr] Data última revisão:
170608
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161203
[St] Status:MEDLINE


  7 / 481 MEDLINE  
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Registro de Ensaios Clínicos
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[PMID]:27480288
[Au] Autor:Gu H; Zheng H; Cui X; Huang Y; Jiang B
[Ad] Endereço:Guangdong Provincial Key Laboratory of Gastroenterology, Department of Gastroenterology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
[Ti] Título:Maneuverability and safety of a magnetic-controlled capsule endoscopy system to examine the human colon under real-time monitoring by colonoscopy: a pilot study (with video).
[So] Source:Gastrointest Endosc;85(2):438-443, 2017 Feb.
[Is] ISSN:1097-6779
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND AND AIMS: Colon capsule endoscopy has become an alternative method to evaluate the colonic mucosa without pain, sedation, and gas insufflation in recent years. The magnetic-controlled capsule endoscopy (MCCE) system is an innovative ingestible colon capsule. We performed a pilot study to assess its maneuverability and safety among subjects who volunteered to undergo colorectal cancer screening. METHODS: Fifty-seven volunteers underwent both MCCE and colonoscopy procedures. The position of the MCCE was monitored after the capsule was swallowed. When the MCCE reached the cecum, it was controlled by a magnetic manipulator to observe the colonic mucosa under real-time monitoring by colonoscopy. The primary measurements included maneuverability, the level of cleanliness, lesions, and safety. RESULTS: Five volunteers (8.78%) were excluded because of bowel preparation protocol deviations or failure to reach the cecum before the battery was exhausted. There was no capsule retention. Maneuverability of the MCCE to match the guidance of the magnetic manipulator was graded as good in 49 subjects (94.23%) and moderate in 3 (5.77%). It took 3.63 ± 1.14 hours for the MCCE to reach the cecum. In 52 subjects (100%) the MCCE reached the transverse colon positively, and in 41 subjects (78.84%) the MCCE reached the rectosigmoid colon within a limited time of 25 minutes. The bowel preparation for MCCE was rated as good or excellent in 84.61% of the volunteers. Six positive findings were identified by the MCCE in the colon, which were also confirmed by colonoscopy. CONCLUSIONS: The MCCE showed promising maneuverability under real-time monitoring by colonoscopy. (Clinical trial registration number: NCT02536144.).
[Mh] Termos MeSH primário: Endoscopia por Cápsula/métodos
Colo/patologia
Colonoscopia/métodos
Neoplasias Colorretais/diagnóstico
Detecção Precoce de Câncer/métodos
Imãs
[Mh] Termos MeSH secundário: Adulto
Cápsulas Endoscópicas
Neoplasias Colorretais/patologia
Estudos de Viabilidade
Feminino
Seres Humanos
Mucosa Intestinal
Masculino
Meia-Idade
Projetos Piloto
Estudos Prospectivos
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; VIDEO-AUDIO MEDIA
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170918
[Lr] Data última revisão:
170918
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160803
[Cl] Clinical Trial:ClinicalTrial
[St] Status:MEDLINE


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[PMID]:27416587
[Au] Autor:Leung BHK; Poon CCY; Zhang R; Zheng Y; Chan CKW; Chiu PWY; Lau JYW; Sung JJY
[Ti] Título:A Therapeutic Wireless Capsule for Treatment of Gastrointestinal Haemorrhage by Balloon Tamponade Effect.
[So] Source:IEEE Trans Biomed Eng;64(5):1106-1114, 2017 May.
[Is] ISSN:1558-2531
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: Wireless capsule endoscope (WCE) is a revolutionary approach to diagnose small bowel pathologies. Currently available WCEs are mostly passive devices with image capturing function only, while on-going efforts have been placed on robotizing WCEs or to enhance them with therapeutic functions. In this paper, the authors present a novel inflatable WCE for haemostasis in the gastrointestinal (GI) tracts by balloon tamponade effect. METHODS: The proposed wireless capsule consists of a balloon that can be inflated using the endothermic reaction of acid and base. When the balloon reached a precalculated pressure level, it is able to stop at a bleeding site in the bowel, and achieve haemostasis by tamponade effect. The prototype is 14 mm in diameter, with three sections of 13, 35, and 12 mm in length, respectively. The three sections are linked together with flexible joints and enclosed in a silicone balloon. The prototypes were tested in ex vivo porcine intestine models. RESULTS: In the ten ex vivo trials conducted, the inflatable wireless capsule achieved average balloon pressure of 46.0 mmHg and withstood average maximum longitudinal pulling force at 1.46 N. An in vivo study was carried out as a proof-of-concept for treating bleeding in a porcine model. The proposed inflatable WCE succeeded in the animal test by controlling haemostasis within 5 min. No rebleeding was observed in the next 20 min. CONCLUSION: The results suggested that the inflatable capsule with a real-time bleeding detection algorithm can be implemented. Moreover, the proposed inflatable WCE prototype can achieve haemorrhage control in the lower GI. SIGNIFICANCE: To our best knowledge, this is the first study that demonstrated the potential to treat GI haemorrhage by an inflatable WCE. The proposed capsule enables the development of a closed-loop system based on a body sensor network to provide early treatment of GI bleeding for p-medicine.
[Mh] Termos MeSH primário: Oclusão com Balão/instrumentação
Cápsulas Endoscópicas
Endoscopia por Cápsula/instrumentação
Hemorragia Gastrointestinal/patologia
Hemorragia Gastrointestinal/terapia
Tecnologia sem Fio/instrumentação
[Mh] Termos MeSH secundário: Animais
Oclusão com Balão/métodos
Endoscopia por Cápsula/métodos
Desenho de Equipamento
Análise de Falha de Equipamento
Sistemas Microeletromecânicos/instrumentação
Miniaturização
Suínos
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171024
[Lr] Data última revisão:
171024
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160715
[St] Status:MEDLINE
[do] DOI:10.1109/TBME.2016.2591060


  9 / 481 MEDLINE  
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[PMID]:27156654
[Au] Autor:Araujo IK; Pages M; Romero C; Castells A; González-Suárez B
[Ad] Endereço:Endoscopy Unit, Gastroenterology Department, Radiology Department, Hospital Clinic, Barcelona, Spain.
[Ti] Título:Twelve-year asymptomatic retention of a colon capsule endoscope.
[So] Source:Gastrointest Endosc;85(3):681-682, 2017 Mar.
[Is] ISSN:1097-6779
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Polipose Adenomatosa do Colo/cirurgia
Doenças Assintomáticas
Cápsulas Endoscópicas
Corpos Estranhos/diagnóstico por imagem
Íleo
Proctocolectomia Restauradora
[Mh] Termos MeSH secundário: Adulto
Endoscopia por Cápsula
Corpos Estranhos/cirurgia
Seres Humanos
Masculino
Tomografia Computadorizada por Raios X
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170928
[Lr] Data última revisão:
170928
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160510
[St] Status:MEDLINE


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[PMID]:27889734
[Au] Autor:Aihole JS; Vishnumurthy GS; Babu MN
[Ad] Endereço:Departments of Pediatric Surgery and *Paediatric Gastroenterology, IGICH Bangalore, Karnataka, India. Correspondence to: Dr Jayalaxmi S Aihole, Department of Pediatric surgery, IGICH, Bangalore, Karnataka, India. jayalaxmisaihole@yahoo.com.
[Ti] Título:Retained Capsule Endoscope.
[So] Source:Indian Pediatr;53(11):1017-1018, 2016 Nov 15.
[Is] ISSN:0974-7559
[Cp] País de publicação:India
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Capsule endoscopy was invented to visualize the entire small intestine in a non- invasive manner in adults. CASE CHARACTERISTICS: 1 y, 9 mo-old boy presented with generalized edema for last 3 months. His routine investigations, including the upper gastrointestinal endoscopy, colonoscopy, and contrast enhanced computed tomography scan (CECT) were normal. In view of clinical suspicion of protein losing enteropathy, we planned capsule endoscopy. OBSERVATION: The capsule was not passed even after 3 weeks. Laparoscopy revealed impacted capsule in a dilated intestinal loop proximal to an ileal stricuture. MESSAGE: Capsule endoscopy should be used judiciously in children.
[Mh] Termos MeSH primário: Cápsulas Endoscópicas/efeitos adversos
Corpos Estranhos
Intestino Delgado
[Mh] Termos MeSH secundário: Edema
Corpos Estranhos/diagnóstico por imagem
Corpos Estranhos/cirurgia
Seres Humanos
Lactente
Intestino Delgado/diagnóstico por imagem
Intestino Delgado/cirurgia
Masculino
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161128
[St] Status:MEDLINE



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