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[PMID]:29217021
[Au] Autor:Ross M; Deschênes J
[Ad] Endereço:Department of Ophthalmology, McGill University Health Center, McGill University, Montreal, Que.. Electronic address: michael.ross4@mail.mcgill.ca.
[Ti] Título:Practice patterns in the interdisciplinary management of corneal abrasions.
[So] Source:Can J Ophthalmol;52(6):548-551, 2017 Dec.
[Is] ISSN:1715-3360
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To characterize the treatment and follow-up patterns of corneal abrasions at an academic health centre. METHODS: This is a retrospective review of 90 cases of corneal abrasions over a 2-year period at a tertiary care academic hospital, of which 75 were seen by the ophthalmology department. All consultations primarily for corneal abrasion, as determined by the emergency department physician, were included in the study. Information on treatment regimen, corneal findings by emergency and ophthalmology physicians, time between follow-ups, and final outcomes was collected. RESULTS: Seventy-five patients were seen by ophthalmology a median of 1 day after the emergency room visit. Twenty-five of these patients did not arrive for their subsequent follow-up appointment. Twenty-two of the abrasions were healed by the time of the ophthalmology examination, 51 patients had unhealed corneal abrasions, and 2 had corneal ulcers. Management was changed in 29 of the patients by ophthalmology. The most common management changes were hypertonic saline ointment for prophylaxis or treatment of recurrent erosion syndrome, followed by bandage contact lenses for comfort. CONCLUSIONS: Corneal abrasions are a common condition, and practice patterns for follow-up vary widely. Although the vast majority of patients do very well and likely would heal on their own without ophthalmology referral, it seems reasonable that patients with corneal abrasions are assessed once by an ophthalmologist immediately or possibly up to 1-2 days after the initial emergency visit, depending on the individual patient circumstances.
[Mh] Termos MeSH primário: Lesões da Córnea/terapia
Epitélio Anterior/lesões
Oftalmologistas/estatística & dados numéricos
Equipe de Assistência ao Paciente
Padrões de Prática Médica/estatística & dados numéricos
[Mh] Termos MeSH secundário: Centros Médicos Acadêmicos
Adolescente
Adulto
Idoso
Idoso de 80 Anos ou mais
Bandagens
Lentes de Contato
Serviço Hospitalar de Emergência
Feminino
Seres Humanos
Masculino
Meia-Idade
Pomadas
Equipe de Assistência ao Paciente/estatística & dados numéricos
Estudos Retrospectivos
Solução Salina Hipertônica/administração & dosagem
Centros de Atenção Terciária
Cicatrização
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; MULTICENTER STUDY
[Nm] Nome de substância:
0 (Ointments); 0 (Saline Solution, Hypertonic)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171226
[Lr] Data última revisão:
171226
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171209
[St] Status:MEDLINE


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[PMID]:29055359
[Au] Autor:Thulasi P; Djalilian AR
[Ad] Endereço:Department of Ophthalmology, Emory University, Atlanta, Georgia.
[Ti] Título:Update in Current Diagnostics and Therapeutics of Dry Eye Disease.
[So] Source:Ophthalmology;124(11S):S27-S33, 2017 Nov.
[Is] ISSN:1549-4713
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Dry eye disease (DED) represents a heterogeneous group of conditions with tear film insufficiency and signs and/or symptoms of ocular surface irritation. The clinical manifestations of DED can be highly variable; hence the diagnosis is often based on a combination of symptoms, signs, and clinical tests, given that any one of these alone would miss a significant number of patients. Similarly, the treatment must often be tailored to each patient by targeting the specific mechanisms involved in his or her disease. The purpose of this review is to summarize recent advances that have allowed us to better recognize, categorize, and treat patients with DED. The most notable new diagnostic tests in DED are tear film osmolarity, inflammatory biomarkers, and meibomian gland imaging. Therapeutically, anti-inflammatory therapy, meibomian gland heating and expression, and scleral contact lenses are some of the latest options available for treating DED.
[Mh] Termos MeSH primário: Síndromes do Olho Seco/diagnóstico
Síndromes do Olho Seco/terapia
[Mh] Termos MeSH secundário: Biomarcadores/análise
Lentes de Contato
Técnicas de Diagnóstico Oftalmológico
Seres Humanos
Hipertermia Induzida
Concentração Osmolar
Lágrimas/química
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Biomarkers)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171027
[Lr] Data última revisão:
171027
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171023
[St] Status:MEDLINE


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[PMID]:28950941
[Au] Autor:Mizoguchi S; Iwanishi H; Arita R; Shirai K; Sumioka T; Kokado M; Jester JV; Saika S
[Ad] Endereço:Department of Ophthalmology, Wakayama Medical University, Wakayama, Japan.
[Ti] Título:Ocular surface inflammation impairs structure and function of meibomian gland.
[So] Source:Exp Eye Res;163:78-84, 2017 Oct.
[Is] ISSN:1096-0007
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Dysfunction of the meibomian glands alters secreted meibum quantitatively and qualitatively that can lead to damage to the ocular surface epithelium. In response to an unstable tear film cause by meibomian gland dysfunction, ocular surface epithelium is damaged and expresses inflammatory cytokines leading to secondary ocular inflammation. In turn, inflammatory disorders of the palpebral conjunctiva and lid margin may affect the structure and function of meibomian gland. The disorders include allergic conjunctivitis, long-term usage of contact lenses, dermatological diseases that affect conjunctival homeostasis, Stevens-Johnson's syndrome or chemical burning of the ocular surface and lid margin.
[Mh] Termos MeSH primário: Doenças da Túnica Conjuntiva/complicações
Epitélio Anterior/metabolismo
Doenças Palpebrais/complicações
Glândulas Tarsais/metabolismo
[Mh] Termos MeSH secundário: Lentes de Contato/efeitos adversos
Edema da Córnea/metabolismo
Citocinas/metabolismo
Seres Humanos
Lágrimas/química
Lágrimas/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Cytokines)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170929
[Lr] Data última revisão:
170929
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170928
[St] Status:MEDLINE


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[PMID]:28950936
[Au] Autor:Georgiev GA; Eftimov P; Yokoi N
[Ad] Endereço:St. Kliment Ohridski University of Sofia, Department of Optics and Spectroscopy, Faculty of Physics, 5 James Bourchier Blvd., 1164 Sofia, Bulgaria. Electronic address: ggeorg@phys.uni-sofia.bg.
[Ti] Título:Structure-function relationship of tear film lipid layer: A contemporary perspective.
[So] Source:Exp Eye Res;163:17-28, 2017 Oct.
[Is] ISSN:1096-0007
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Tear film lipid layer (TFLL) stabilizes the air/tear surface of the human eye. Meibomian gland dysfunction (MGD) resulting in quantitative and qualitative modifications of TFLL major (>93%) component, the oily secretion of meibomian lipids (MGS), is the world leading cause of dry eye syndrome (DES) with up to 86% of all DES patients showing signs of MGD. Caused by intrinsic factors (aging, ocular and general diseases) and by extrinsic everyday influences like contact lens wear and extended periods in front of a computer screen, DES (resulting in TF instability, visual disturbances and chronic ocular discomfort) is the major ophthalmic public health disease of the present time affecting the quality of life of 10-30% of the human population worldwide. Therefore there is a pressing need to summarize the present knowledge, contradictions and open questions to be resolved in the field of TFLL composition/structure/functions relationship. The following major aspects are covered by the review: (i) Do we have a reliable mimic for TFLL: MGS vs contact lens lipid extracts (CLLE) vs lipid extracts from whole tears. Does TFLL truly consist of lipids only or it is important to keep in mind the TF proteins as well?; (ii) Structural properties of TFLL and of its mimics in health and disease in vitro and in vivo. How the TFLL uniformity and thickness ensures the functionality of the lipid layer (barrier to evaporation, surface properties, TF stability etc.); (iii) What are the main functions of the TFLL? In this aspect an effort is done to emphasize that there is no single main function of TFLL but instead it simultaneously fulfills plethora of functions: suppresses the evaporation (alone or probably in cooperation with other TF constituents) of the aqueous tears; stabilizes (due to its surface properties) the air/tear surface at eye opening and during the interblink interval; and even acts as a first line of defense against bacterial invasion due to its detergency action on the bacterial membranes. An effort is done to highlight how the concept on the importance of TFLL and TF viscoelasticity transpires from old and new studies and what are its clinical implications. An attempt is made to outline the future hot directions of research into the field ranging from quest for molecules that can significantly alter TFLL properties to addressing open questions on the contribution of TFLL to the overall performance of the TF.
[Mh] Termos MeSH primário: Síndromes do Olho Seco/fisiopatologia
Lipídeos/fisiologia
Glândulas Tarsais/fisiopatologia
Lágrimas/fisiologia
[Mh] Termos MeSH secundário: Lentes de Contato
Metabolismo dos Lipídeos/fisiologia
Lipídeos/secreção
Glândulas Tarsais/secreção
Modelos Biológicos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Lipids)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170929
[Lr] Data última revisão:
170929
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170928
[St] Status:MEDLINE


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[PMID]:28885362
[Au] Autor:Chen L; Pi L; Ke N; Chen X; Liu Q
[Ad] Endereço:Department of Ophthalmology, Children's Hospital, Chongqing Medical University, Chongqing, China.
[Ti] Título:The protective efficacy and safety of bandage contact lenses in children aged 5 to 11 after frontalis muscle flap suspension for congenital blepharoptosis: A single-center randomized controlled trial.
[So] Source:Medicine (Baltimore);96(36):e8003, 2017 Sep.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Postoperative complications, lagophthalmos and exposure keratopathy sometimes occur after surgery for congenital blepharoptosis. Bandage contact lenses (BCL) can help prevent some ocular surface disorders. The study aims to evaluate the efficacy and safety of BCL for protection of the ocular surface in children aged 5 to 11 years after frontalis muscle flap suspension for congenital blepharoptosis. METHODS: We conducted a prospective randomized clinical study of 30 eyes of 30 patients with congenital blepharoptosis consecutively enrolled at the Ophthalmology Ward of the Children's Hospital of Chongqing Medical University, China from September 1, 2016, to February 30, 2017. After frontalis muscle flap suspension surgery, patients were randomly assigned to undergo BCL application (BCL group, 15 eyes) or no BCL application (control group, 15 eyes). All patients were treated with bramycin 0.3% and polyvinyl alcohol drops after surgery. The primary outcomes were dry eye assessed by tear film break time (TFBUT), fluoresce in corneal staining (FCS) on slit-lamp on days 1, 3, and 15 postoperatively, and lower tear meniscus height (LTMH) on optical coherence tomography on days 1 and 15 postoperatively. Secondary outcomes were pairwise correlation of TFBUT, FCS and LTMH. RESULTS: In the BCL group, abnormal TFBUT and FCS were only found in 2 patients (13.33%) on postoperative day 15. In the control group, the incidence of dry eye assessed by TFBUT was 67.00% (10/15 eyes) on day 1, 73.33% (11/15 eyes) on day 3, and 53.33% (8/15 eyes) on day 15 (P < .001). LTMH were significantly higher in the BCL group than the control group postoperatively (P < .001). Significant positive correlations were found between LTMH and TFBUT pre-operation and on days 1 and 15 post-operation. For LTMH and FCSS (R = -0.815, P < .001), and TFBUT and FCS (R = -0.837, P < .001), the Pearson coefficient was negative on postoperative day 1, but not correlated on day 15. CONCLUSIONS: Silicone hydrogel BCL were safe and efficacious for protective use in children after frontalis muscle flap suspension for congenital blepharoptosis.
[Mh] Termos MeSH primário: Bandagens
Blefaroptose/terapia
Lentes de Contato
Complicações Pós-Operatórias/prevenção & controle
Retalhos Cirúrgicos
[Mh] Termos MeSH secundário: Anti-Infecciosos/administração & dosagem
Blefaroptose/diagnóstico por imagem
Criança
Pré-Escolar
Síndromes do Olho Seco/diagnóstico por imagem
Síndromes do Olho Seco/prevenção & controle
Feminino
Seguimentos
Seres Humanos
Hidrogéis
Masculino
Soluções Oftálmicas
Álcool de Polivinil/administração & dosagem
Complicações Pós-Operatórias/diagnóstico por imagem
Silicones
Tomografia de Coerência Óptica
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Anti-Infective Agents); 0 (Hydrogels); 0 (Ophthalmic Solutions); 0 (Silicones); 9002-89-5 (Polyvinyl Alcohol)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170918
[Lr] Data última revisão:
170918
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170909
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000008003


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[PMID]:28873175
[Au] Autor:Gallagher AG; McLean K; Stewart RMK; Wellings DA; Allison HE; Williams RL
[Ad] Endereço:Department of Eye and Vision Science, Institute of Ageing and Chronic Diseases, University of Liverpool, Liverpool, United Kingdom.
[Ti] Título:Development of a Poly-ε-Lysine Contact Lens as a Drug Delivery Device for the Treatment of Fungal Keratitis.
[So] Source:Invest Ophthalmol Vis Sci;58(11):4499-4505, 2017 Sep 01.
[Is] ISSN:1552-5783
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Purpose: The purpose of this study was to develop a more efficient drug delivery device to overcome the limitations of current drop therapy for the treatment of fungal keratitis. Methods: Amphotericin B (AmpB), 0 to 30 µg/mL, was associated with a poly-ε-lysine (pεK) hydrogel. Fungicidal effect against Candida albicans was assessed at 18 and 42 hours by optical density (OD600) and growth on agar. Tear film dilution effect was mimicked by storage of AmpB pεK gels in 3.4 mL sterile PBS for 24 hours prior to fungal incubation. Drug elution over 96 hours was evaluated by HPLC, and drug stability was tested while associated with the gel by OD600 up to 48 hours. Lack of cytotoxicity toward the HCE-T corneal epithelial cell line was assessed over 7 days. Results: AmpB pεK gels show fungicidal activity in normal conditions (0.057 OD600, SD 0.003, P < 0.005) and in the presence of horse serum (0.048 OD600, SD 0.028 P < 0.005) at 18 hours. The drug release profile was above therapeutic levels (0.188 µg/mL) for up to 72 hours. Tear dilution had no significant effect at higher concentrations of AmpB (3 to 10 µg/mL). AmpB pεK gels were not cytotoxic to the HCE-T cell line. Conclusions: We demonstrated that AmpB pεK gels confer sustained therapeutic antifungal activity for at least 48 hours without corneal epithelial cell line cytotoxicity, suggesting their potential for in vivo use as an antifungal bandage contact lens. This could avoid the need for intensive topical medication in the treatment of fungal keratitis.
[Mh] Termos MeSH primário: Anfotericina B/farmacologia
Antifúngicos/farmacologia
Lentes de Contato
Úlcera da Córnea/tratamento farmacológico
Sistemas de Liberação de Medicamentos/instrumentação
Infecções Oculares Fúngicas/tratamento farmacológico
Polilisina/química
[Mh] Termos MeSH secundário: Candida albicans/efeitos dos fármacos
Candidíase/tratamento farmacológico
Candidíase/microbiologia
Linhagem Celular
Sobrevivência Celular
Cromatografia Líquida de Alta Pressão
Úlcera da Córnea/microbiologia
Portadores de Fármacos/farmacologia
Epitélio Anterior/efeitos dos fármacos
Infecções Oculares Fúngicas/microbiologia
Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antifungal Agents); 0 (Drug Carriers); 25104-18-1 (Polylysine); 7XU7A7DROE (Amphotericin B)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170919
[Lr] Data última revisão:
170919
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170906
[St] Status:MEDLINE
[do] DOI:10.1167/iovs.17-22301


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[PMID]:28858004
[Au] Autor:Altoaimi BH; Almutairi MS; Kollbaum P; Bradley A
[Ad] Endereço:1School of Optometry, Indiana University, Bloomington, Indiana 2Department of Optometry, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia *baltoaim@indiana.edu.
[Ti] Título:Accommodative Behavior of Eyes Wearing Aspheric Single Vision Contact Lenses.
[So] Source:Optom Vis Sci;94(10):971-980, 2017 Oct.
[Is] ISSN:1538-9235
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:SIGNIFICANCE: Wearing aspheric contact lenses adds significant amounts of negative spherical aberration (SA). Also, when accommodated and converged to near targets, pupil size shrinks and SA shift from positive to more negative direction. Interestingly, in this study, pupil miosis was fully or partially able to compensate for the additional accommodation-induced negative SA. PURPOSE: The present study aims to examine the accommodative response characteristics of young eyes fit with aspheric single vision contact lenses (SVCLs) that add significant negative SA to the eye responding to a wide range of accommodation stimuli. METHODS: Using a Shack-Hartmann aberrometer, the accommodation behavior in eight young adult eyes (mean age and spherical equivalent is 27.25 ± 2.05 years and -1.75 ± 1.80D, respectively) was measured while subjects fixated binocularly and monocularly 20/40 letter E, which were moved from 2 m to 20 cm (0.5 to 5D) in 0.25D steps. Using natural pupils, refractive state was defined using three standard criteria: the dioptric power that (1) minimized the root mean square error (minRMS), (2) best-fit paraxial, and (3) provided the peak image quality (peak IQ). RESULTS: Wearing aspheric lenses with negative SA shifts the mean SA of the unaccommodated eyes from +0.05 µm (eyes only) to -0.029 µm (eyes + SVCL) and increases the negative SA for the eye + lens when accommodating from -0.029 to -0.07 µm for natural pupils. Aberration changes with accommodation were attenuated by the accommodative pupil miosis, which reduced binocular viewing pupil diameters from 3.9 to 3.3 mm. This alteration of the typical SA levels by the aspheric SVCL did not prevent accurate accommodation (mean ± standard deviation accommodative lag under binocular viewing were -0.08 ± 0.12D, -0.38 ± 0.12D, and -0.26 ± 0.08D for paraxial, minRMS, and peak IQ, respectively). CONCLUSIONS: These data clearly show that aspheric contact lenses designed to correct some or all of the unaccommodated eye's positive SA do not interfere with accommodation.
[Mh] Termos MeSH primário: Acomodação Ocular/fisiologia
Lentes de Contato
Miopia/fisiopatologia
Pupila/fisiologia
Refração Ocular/fisiologia
Acuidade Visual
[Mh] Termos MeSH secundário: Adulto
Desenho de Equipamento
Feminino
Seres Humanos
Masculino
Miopia/terapia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171018
[Lr] Data última revisão:
171018
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170901
[St] Status:MEDLINE
[do] DOI:10.1097/OPX.0000000000001121


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[PMID]:28820753
[Au] Autor:Bendavid I; Avisar I; Serov Volach I; Sternfeld A; Dan Brazis I; Umar L; Yassur Y; Singer P; Cohen JD
[Ad] Endereço:1Department of General Intensive Care, Rabin Medical Center, Campus Beilinson, Petah Tikva, Israel. 2Department of Opthalmology, Rabin Medical Center, Campus Beilinson, Petah Tikva, Israel. 3Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
[Ti] Título:Prevention of Exposure Keratopathy in Critically Ill Patients: A Single-Center, Randomized, Pilot Trial Comparing Ocular Lubrication With Bandage Contact Lenses and Punctal Plugs.
[So] Source:Crit Care Med;45(11):1880-1886, 2017 Nov.
[Is] ISSN:1530-0293
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: To compare the effectiveness of bandage contact lenses and punctal plugs with ocular lubricants in preventing corneal damage in mechanically ventilated and sedated critically ill patients. DESIGN: Single-center, prospective, randomized, pilot study. SETTING: Sixteen-bed, general ICU at a tertiary academic medical center. PATIENTS: Adults admitted to the ICU and anticipated to require mechanical ventilation and continuous sedation for greater than or equal to 4 days. INTERVENTIONS: Patients were randomized to receive eye care with ocular lubricants (n = 38), bandage contact lenses (n = 33), or punctal plugs (n = 33). The bandage contact lenses were changed every 4 days, whereas the punctal plugs remained in situ for the entire study. MEASUREMENTS AND MAIN RESULTS: The primary endpoint was the presence or absence of corneal damage as assessed by the grade of keratopathy. Patients were examined by an ophthalmologist blinded to the study group every 4 days and at the time of withdrawal from the study, due to cessation of sedation, discharge from the ICU, or death. The mean duration of the study was 8.6 ± 6.2 days. The grade of keratopathy in the ocular lubricant group increased significantly in both eyes (p = 0.01 for both eyes) while no worsening was noted in either the lens or punctal plugs groups. In a post hoc analysis of patients with an initially abnormal ophthalmic examination, significant healing of keratopathy was noted in the lens group (p = 0.02 and 0.018 for left and right eyes, respectively) and in the right eye of the plugs group (p = 0.005); no improvement was noted in the ocular lubricant group. CONCLUSIONS: Compared with ocular lubrication, bandage contact lenses and punctal plugs were more effective in limiting keratopathy, and their use, particularly of bandage contact lenses, was associated with significant healing of existing lesions.
[Mh] Termos MeSH primário: Lentes de Contato
Doenças da Córnea/prevenção & controle
Estado Terminal
Lubrificantes Oftálmicos/administração & dosagem
Plug Lacrimal
[Mh] Termos MeSH secundário: Centros Médicos Acadêmicos
Idoso
Idoso de 80 Anos ou mais
Método Duplo-Cego
Feminino
Seres Humanos
Unidades de Terapia Intensiva
Masculino
Meia-Idade
Projetos Piloto
Estudos Prospectivos
Respiração Artificial/efeitos adversos
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Lubricant Eye Drops)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171025
[Lr] Data última revisão:
171025
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170819
[St] Status:MEDLINE
[do] DOI:10.1097/CCM.0000000000002681


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[PMID]:28817556
[Au] Autor:Cope JR; Collier SA; Nethercut H; Jones JM; Yates K; Yoder JS
[Ad] Endereço:Division of Foodborne, Waterborne, and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, CDC.
[Ti] Título:Risk Behaviors for Contact Lens-Related Eye Infections Among Adults and Adolescents - United States, 2016.
[So] Source:MMWR Morb Mortal Wkly Rep;66(32):841-845, 2017 Aug 18.
[Is] ISSN:1545-861X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Contact lens-related eye infections, which can lead to serious outcomes, including blindness, are associated with several risk factors, including sleeping in lenses, exposing lenses to water, not adhering to replacement schedules, and reusing disinfecting solution (1). In some studies, adolescent and young adult contact lens wearers have been reported to be more likely than older adult contact lens wearers to develop eye infections (2,3) and more likely to have poor contact lens hygiene practices (2). In 2015, CDC reported the number and demographics of adult contact lens wearers in the United States to define the population at risk for contact lens-related eye infections (4); however, this estimate did not include adolescents. To better understand this group of younger contact lens wearers and guide prevention efforts, a population-based survey was used to assess contact lens wear, care behaviors, risk factors, and demographics among persons aged 12-17 years (referred to as adolescents in this report), young adults aged 18-24 years, and older adults aged ≥25 years in the United States. In 2016, an estimated 3.6 million adolescents (14.5%) wore contact lenses. Of the adolescents who wore contact lenses, 85% reported at least one behavior that put them at risk for a contact lens-related eye infection, compared with 81% of young adults, and 88% of older adults. These findings can inform the creation of age-specific targeted prevention messages aimed at contact lens wearers and establish a baseline for evaluating trends in contact lens wear, care habits, and contact lens-related risk behaviors.
[Mh] Termos MeSH primário: Lentes de Contato/efeitos adversos
Lentes de Contato/psicologia
Infecções Oculares/epidemiologia
Assunção de Riscos
[Mh] Termos MeSH secundário: Adolescente
Adulto
Criança
Feminino
Seres Humanos
Masculino
Estados Unidos/epidemiologia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170821
[Lr] Data última revisão:
170821
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170818
[St] Status:MEDLINE
[do] DOI:10.15585/mmwr.mm6632a2


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[PMID]:28816867
[Au] Autor:Fedtke C; Ehrmann K; Thomas V; Bakaraju RC
[Ad] Endereço:1The Brien Holden Vision Institute, Sydney, New South Wales, Australia 2School of Optometry and Vision Science, The University of New South Wales, Sydney, New South Wales, Australia.
[Ti] Título:Peripheral Refraction and Aberration Profiles with Multifocal Lenses.
[So] Source:Optom Vis Sci;94(9):876-885, 2017 Sep.
[Is] ISSN:1538-9235
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:SIGNIFICANCE: The amount of central or peripheral myopic shift, as induced by different multifocal contact lenses when viewing objects at distance or near, may provide insights on the potential efficacy for slowing eye growth. PURPOSE: The present study aims to compare peripheral refraction and higher-order aberration profiles of four multifocal contact lenses with a single vision control lens. METHODS: Thirty-five myopes (age 21.2 ± 2.1 years) completed the trial, of whom 16 wore Air Optix Aqua and Proclear Multifocal Distance and Near (Group 1, spherical equivalent: -2.90 ± 0.95D), whereas 19 wore Air Optix Aqua, Air Optix Multifocal, and PureVision Multifocal (Group 2, spherical equivalent: -2.95 ± 0.78D). Refraction and aberration profiles with lenses were measured using the BHVI-EyeMapper with (-2.00 to -5.00D in 1.00D steps) and without (+1.00D fogging) accommodation. Data were quantified using M2/4 (2nd and 2nd + 4th order), J0, J45, and higher-order aberration coefficients coma C[3, 1] and spherical aberration C[4, 0]. RESULTS: The center-distance lens exhibited a relative peripheral myopic shift in M2/4 and J0, positive on-axis C[4, 0], negative on-axis C[3, 1] and on-axis M4 was less negative for accommodative demands ≤-3.00D (P < .05). Inversely, the center-near lenses showed a relative peripheral hyperopic shift in M2/4 and J0, negative on-axis C[4, 0], positive on-axis C[3, 1] and on-axis M4 was more negative for demands of -2.00 and -3.00D (P < .05). Independent of lens type, relative peripheral M4 significantly decreased during accommodation. Accounting for C[4, 0], a greater change in relative M profiles and accommodative responses was found for multifocal lenses. CONCLUSIONS: Based on the hypothesis that myopic retinal defocus counters eye growth, center-near multifocal lenses exhibited the preferred on-axis features, i.e., producing a central myopic shift at near compared to the control. The center-distance lens exhibited preferred off-axis features, producing relative peripheral myopia, which increased further during accommodation.
[Mh] Termos MeSH primário: Acomodação Ocular/fisiologia
Lentes de Contato
Miopia/terapia
Refração Ocular/fisiologia
[Mh] Termos MeSH secundário: Aberrometria
Adolescente
Adulto
Desenho de Equipamento
Feminino
Seres Humanos
Masculino
Miopia/fisiopatologia
Estudos Prospectivos
Método Simples-Cego
Testes Visuais
Acuidade Visual
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170919
[Lr] Data última revisão:
170919
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170818
[St] Status:MEDLINE
[do] DOI:10.1097/OPX.0000000000001112



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