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[PMID]:29447172
[Au] Autor:Alemayehu AM; Belete GT; Adimassu NF
[Ad] Endereço:Department of Optometry, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
[Ti] Título:Knowledge, attitude and associated factors among primary school teachers regarding refractive error in school children in Gondar city, Northwest Ethiopia.
[So] Source:PLoS One;13(2):e0191199, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: Refractive error is an important cause of correctable visual impairment in the worldwide with a global distribution of 1.75% to 20.7% among schoolchildren. Teacher's knowledge about refractive error play an important role in encouraging students to seek treatment that helps in reducing the burden of visual impairment. OBJECTIVE: To determine knowledge, attitude and associated factors among primary school teachers regarding refractive error in school children in Gondar city. METHODS: Institution based cross-sectional study was conducted on 565 primary school teachers in Gondar city using pretested and structured self-administered questionnaire. For processing and analysis, SPSS version 20 was used and variables which had a P value of <0.05 in the multivariable analysis were considered as statistically significant. RESULT: A total of 565 study subjects were participated in this study with a mean age of 42.05 ± 12.01 years. Of these study participants 55.9% (95% CI: 51.9, 59.8) had good knowledge and 57.2% (95% CI: 52.9, 61.4) had favorable attitude towards refractive error. History of spectacle use [AOR = 2.13 (95% CI: 1.32, 3.43)], history of eye examination [AOR = 1.67 (95% CI: 1.19, 2.34)], training on eye health [AOR = 1.94 (95% CI; 1.09, 3.43)] and 11-20 years of experience [AOR = 2.53 (95% CI: 1.18, 5.43)] were positively associated with knowledge. Whereas being male [AOR = 2.03 (95% CI: 1.37, 3.01)], older age [AOR = 3.05 (95% CI: 1.07, 8.72)], 31-40 years of experience [AOR = 0.23 (95% CI: 0.07, 0.72)], private school type [AOR = 1.76 (95% CI: 1.06, 2.93)] and 5th -8th teaching category [AOR = 1.54 (95% CI: 1.05, 2.24)] were associated with attitude. CONCLUSION: Knowledge and attitude of study subjects were low which needs training of teachers about the refractive error.
[Mh] Termos MeSH primário: Conhecimentos, Atitudes e Prática em Saúde
Capacitação de Professores/métodos
[Mh] Termos MeSH secundário: Adulto
Estudos Transversais
Etiópia
Óculos
Feminino
Seres Humanos
Conhecimento
Masculino
Meia-Idade
Erros de Refração/diagnóstico
Erros de Refração/etiologia
Erros de Refração/prevenção & controle
Fatores de Risco
Professores Escolares
Instituições Acadêmicas
Estudantes
Inquéritos e Questionários
Capacitação de Professores/classificação
Baixa Visão
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180216
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0191199


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[PMID]:28746982
[Au] Autor:Irving EL; Yakobchuk-Stanger C
[Ad] Endereço:School of Optometry and Vision Science, University of Waterloo, Waterloo, Canada.
[Ti] Título:Myopia progression control lens reverses induced myopia in chicks.
[So] Source:Ophthalmic Physiol Opt;37(5):576-584, 2017 09.
[Is] ISSN:1475-1313
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:PURPOSE: To determine whether lens induced myopia in chicks can be reversed or reduced by wearing myopia progression control lenses of the same nominal (central) power but different peripheral designs. METHODS: Newly hatched chicks wore -10D Conventional lenses unilaterally for 7 days. The myopic chicks were then randomly divided into three groups: one fitted with Type 1 myopia progression control lenses, the second with Type 2 myopia progression control lenses and the third continued to wear Conventional lenses for seven more days. All lenses had -10D central power, but Type 1 and Type 2 lenses had differing peripheral designs; +2.75D and +1.32D power rise at pupil edge, respectively. Axial length and refractive error were measured on Days 0, 7 and 14. Analyses were performed on the mean differences between treated and untreated eyes. RESULTS: Refractive error and axial length differences between treated and untreated eyes were insignificant on Day 0. On Day 7 treated eyes were longer (T1; 0.44 ± 0.07 mm, T2; 0.27 ± 0.06 mm, C; 0.40 ± 0.06 mm) and more myopic (T1; -9.61 ± 0.52D, T2; -9.57 ± 0.61D, C; -9.50 ± 0.58D) than untreated eyes with no significant differences between treatment groups. On Day 14 myopia was reversed (+2.91 ± 1.08D), reduced (-3.83 ± 0.94D) or insignificantly increased (-11.89 ± 0.79D) in treated eyes of Type 1, Type 2 and Conventional treated chicks respectively. Relative changes in axial lengths (T1; -0.13 ± 0.09 mm, T2; 0.36 ± 0.09 mm, C; 0.56 ± 0.05 mm) were consistent with changes in refraction. Refractive error differences were significant for all group comparisons (p < 0.001). Type 1 length differences were significantly different from Conventional and Type 2 groups (p < 0.001). CONCLUSIONS: Myopia progression control lens designs can reverse lens-induced myopia in chicks. The effect is primarily due to axial length changes. Different lens designs produce different effects indicating that lens design is important in modifying refractive error.
[Mh] Termos MeSH primário: Óculos
Miopia/terapia
Refração Ocular/fisiologia
[Mh] Termos MeSH secundário: Animais
Galinhas
Modelos Animais de Doenças
Progressão da Doença
Miopia/diagnóstico
Miopia/fisiopatologia
Privação Sensorial
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1709
[Cu] Atualização por classe:180305
[Lr] Data última revisão:
180305
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170727
[St] Status:MEDLINE
[do] DOI:10.1111/opo.12400


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[PMID]:29204689
[Au] Autor:Kim SJ; Jeon H; Jung JH; Lee KM; Choi HY
[Ad] Endereço:Department of Ophthalmology, School of Medicine, Gyeongsang National University, Gyeongsang National University Changwon Hospital, Changwon, South Korea.
[Ti] Título:Comparison between over-glasses patching and adhesive patching for children with moderate amblyopia: a prospective randomized clinical trial.
[So] Source:Graefes Arch Clin Exp Ophthalmol;256(2):429-437, 2018 Feb.
[Is] ISSN:1435-702X
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:PURPOSE: To investigate efficacy of over-glasses patching treatment for amblyopic children using visual function improvement and Amblyopia Treatment Index (ATI) changes. METHODS: In a randomized multi-center controlled clinical trial, 107 children aged 3-7 years with moderate amblyopia (visual acuity in the range of 20/40 to 20/100) were included to receive treatment with either an adhesive skin patch or a fabric over-glasses patch. The patients were prescribed 2 h of patching per day for the sound eye. Best-corrected visual acuity (BCVA) was investigated and ATI questionnaires were collected from parents at 5 weeks and 17 weeks after the initiation of treatment. ATI identifies barriers and problems associated with amblyopia treatment. We compared the changes of visual acuity of amblyopic eyes and ATI scores in two groups. RESULTS: At 17 weeks, the mean visual acuity of the amblyopic eye using Snellen chart improved 3.2 lines in the adhesive patching group and 2.7 lines for an over-glasses patching method that fit over eyeglasses (p = 0.345). A similar proportion of subjects in each group had improvement of ≥ 2 lines (adhesive patching group 67% vs over-glasses patching group 67%, p = 0.372). There was also no difference in treatment burden in each group as measured with the Amblyopia Treatment Index. The only item to demonstrate a significant difference between groups was that related to "Treatment makes the eye or eyelids red" (mean 4.0 ± 1.1 vs 3.0 ± 1.0 at 17 weeks, p = 0.001, for adhesive vs over-glasses patch). CONCLUSIONS: Over-glasses patching treatment is a useful option for amblyopia treatment when the patients suffer from adverse effects of using adhesive skin patching.
[Mh] Termos MeSH primário: Adesivos
Ambliopia/terapia
Óculos
Privação Sensorial
Visão Binocular/fisiologia
Acuidade Visual/fisiologia
[Mh] Termos MeSH secundário: Ambliopia/diagnóstico
Ambliopia/fisiopatologia
Criança
Pré-Escolar
Seguimentos
Seres Humanos
Estudos Prospectivos
Índice de Gravidade de Doença
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE; MULTICENTER STUDY; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Adhesives)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180214
[Lr] Data última revisão:
180214
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171206
[St] Status:MEDLINE
[do] DOI:10.1007/s00417-017-3851-2


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[PMID]:29172310
[Au] Autor:Casaus A; Patel B; Brown L; Coomaraswamy K
[Ti] Título:Could Video Glasses Contribute to Behaviour Management in the 21st Century?
[So] Source:Dent Update;44(1):45-8, 51, 2017 Jan.
[Is] ISSN:0305-5000
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Dental fear in the paediatric population can be a significant barrier to providing optimal dental care. Pharmacological management techniques utilized to manage anxiety, such as conscious sedation and general anaesthesia, are expensive and require specialized equipment with additional staff training. With recent advances in technology, video glasses are an economic and novel distraction technique that may aid in improving behaviour management and facilitate dental treatment. Clinical relevance: Nervous children may find difficulty in accessing care owing to their inability to co-operate and accept dental treatment. This paper describes an innovative technique that may aid the clinician in overcoming this barrier.
[Mh] Termos MeSH primário: Ansiedade ao Tratamento Odontológico/prevenção & controle
Assistência Odontológica para Crianças/métodos
Óculos
Gravação em Vídeo
[Mh] Termos MeSH secundário: Criança
Comportamento Infantil
Assistência Odontológica para Crianças/tendências
Previsões
Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180123
[Lr] Data última revisão:
180123
[Sb] Subgrupo de revista:D
[Da] Data de entrada para processamento:171128
[St] Status:MEDLINE


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[PMID]:29197362
[Au] Autor:Azizoglu S; Crewther SG; Serefhan F; Barutchu A; Göker S; Junghans BM
[Ad] Endereço:School of Psychology and Public Health, La Trobe University, Bundoora, VIC, 3086, Australia.
[Ti] Título:Evidence for the need for vision screening of school children in Turkey.
[So] Source:BMC Ophthalmol;17(1):230, 2017 Dec 02.
[Is] ISSN:1471-2415
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: In many countries, access to general health and eye care is related to an individual's socioeconomic status (SES). We aimed to examine the prevalence of oculo-visual disorders in children in Istanbul Turkey, drawn from schools at SES extremes but geographically nearby. METHODS: Three school-based vision screenings (presenting distance visual acuity, cover test, eye assessment history, colour vision, gross stereopsis and non-cycloplegic autorefraction) were conducted on 81% of a potential 1014 primary-school children aged 4-10 years from two private (high SES) schools and a nearby government (low SES) school in central Istanbul. Prevalence of refractive errors and school-based differences were analysed using parametric statistics (ANOVA). The remaining oculo-visual aspects were compared using non-parametric tests. RESULTS: Of the 823 children with mean age 6.7 ± 2.2 years, approximately 10% were referred for a full eye examination (8.2% and 16.3% of private/government schools respectively). Vision had not been previously examined in nearly 22% of private school children and 65% of government school children. Of all children, 94.5% were able to accurately identify the 6/9.5 [LogMAR 0.2] line of letters/shapes with each eye and 86.6% the 6/6 line [LogMAR 0], while 7.9% presented wearing spectacles, 3.8% had impaired colour vision, 1.5% had grossly impaired stereo-vision, 1.5% exhibited strabismus, 1.8% were suspected to have amblyopia and 0.5% had reduced acuity of likely organic origin. Of the 804 without strabismus, amblyopia or organic conditions, 6.0% were myopic ≤ - 0.50DS, 0.6% hyperopic ≥ + 2.00DS, 7.7% astigmatic ≥1.00 DC and 6.2% anisometropic ≥1.00DS. CONCLUSIONS: The results highlight the need for general vision screenings for all children prior to school entry given the varied and different pattern of visual problems associated with lifestyle differences in two populations raised in the same urban locale but drawn from different socioeconomic backgrounds.
[Mh] Termos MeSH primário: Necessidades e Demandas de Serviços de Saúde/estatística & dados numéricos
Transtornos da Visão/epidemiologia
Seleção Visual/normas
[Mh] Termos MeSH secundário: Análise de Variância
Criança
Pré-Escolar
Óculos/estatística & dados numéricos
Feminino
Seres Humanos
Masculino
Prevalência
Turquia/epidemiologia
Acuidade Visual
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171220
[Lr] Data última revisão:
171220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171204
[St] Status:MEDLINE
[do] DOI:10.1186/s12886-017-0618-9


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[PMID]:29183275
[Au] Autor:Zhu M; Tong X; Zhao R; He X; Zhao H; Zhu J
[Ad] Endereço:Shanghai Eye Disease Prevention and Treatment Center, No. 380 Kangding Road, Jingan District, Shanghai, 200040, China.
[Ti] Título:Prevalence and associated risk factors of undercorrected refractive errors among people with diabetes in Shanghai.
[So] Source:BMC Ophthalmol;17(1):220, 2017 Nov 28.
[Is] ISSN:1471-2415
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: To investigate the prevalence and risk factors of undercorrected refractive error (URE) among people with diabetes in the Baoshan District of Shanghai, where data for undercorrected refractive error are limited. METHODS: The study was a population-based survey of 649 persons (aged 60 years or older) with diabetes in Baoshan, Shanghai in 2009. One copy of the questionnaire was completed for each subject. Examinations included a standardized refraction and measurement of presenting and best-corrected visual acuity (BCVA), tonometry, slit lamp biomicroscopy, and fundus photography. RESULTS: The calculated age-standardized prevalence rate of URE was 16.63% (95% confidence interval [CI] 13.76-19.49). For visual impairment subjects (presenting vision worse than 20/40 in the better eye), the prevalence of URE was up to 61.11%, and 75.93% of subjects could achieve visual acuity improvement by at least one line using appropriate spectacles. Under multiple logistic regression analysis, older age, female gender, non-farmer, increasing degree of myopia, lens opacities status, diabetic retinopathy (DR), body mass index (BMI) index lower than normal, and poor glycaemic control were associated with higher URE levels. Wearing distance eyeglasses was a protective factor for URE. CONCLUSION: The undercorrected refractive error in diabetic adults was high in Shanghai. Health education and regular refractive assessment are needed for diabetic adults. Persons with diabetes should be more aware that poor vision is often correctable, especially for those with risk factors.
[Mh] Termos MeSH primário: Erros de Refração/epidemiologia
[Mh] Termos MeSH secundário: Fatores Etários
Idoso
Idoso de 80 Anos ou mais
Índice de Massa Corporal
China/epidemiologia
Retinopatia Diabética/complicações
Óculos
Feminino
Seres Humanos
Modelos Logísticos
Masculino
Meia-Idade
Prevalência
Erros de Refração/etiologia
Fatores de Risco
Fatores Sexuais
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171219
[Lr] Data última revisão:
171219
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171130
[St] Status:MEDLINE
[do] DOI:10.1186/s12886-017-0620-2


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[PMID]:28229606
[Au] Autor:Veselý P; Spurná G; Hanák L; Synek S
[Ti] Título:[Disorders of Simple Binocular Vision in Heterophoria and their Spectacle Correction].
[Ti] Título:Poruchy jednoduchého binokulárního videní u heteroforií a jejich resení brýlovou korekcí..
[So] Source:Cesk Slov Oftalmol;72(6):223-225, 2016.
[Is] ISSN:1211-9059
[Cp] País de publicação:Czech Republic
[La] Idioma:cze
[Ab] Resumo:This study deals with evaluation of binocular vision in group of young subjects without eye pathology. We examined at whole 68 subjects with average age 26 years, median 24 years. The sample was divided into two main groups. Group A contains subjects with far and near ortophoria (at whole 26 subjects = 38 %). Group B contains subjects with binocular vision disorder (at whole 42 subjects). One subject had strabismus. The most frequent non-strabismus disorder of binocular vision was convergence insufficiency (13 subjects = 19 %), simple esophoria (12 subjects = 17 %) and simple exophoria (8 subjects = 12 %). We decreased average distance heterophoria value (from 1.02 to 0.36 cm/m esophoria) and near heterophoria value (from 0.60 to 0.31 cm/m exophoria) after proper sphere-cylindrical correction. Result of our study shows that adequate and actual sphere-cylindrical correction can reduce disorder of simple binocular vision.Key words: simple binocular vision, heterophoria, spectacle lenses, convergence insufficiency.
[Mh] Termos MeSH primário: Óculos
Transtornos da Motilidade Ocular/fisiopatologia
Estrabismo/fisiopatologia
Transtornos da Visão/fisiopatologia
Visão Binocular/fisiologia
[Mh] Termos MeSH secundário: Adulto
Feminino
Seres Humanos
Masculino
Transtornos da Motilidade Ocular/terapia
Estrabismo/terapia
Transtornos da Visão/terapia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171128
[Lr] Data última revisão:
171128
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170224
[St] Status:MEDLINE


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[PMID]:28836389
[Au] Autor:de Gracia P; Hartwig A
[Ad] Endereço:Midwestern University, Chicago College of Optometry, Downers Grove, IL, USA.
[Ti] Título:Optimal orientation for angularly segmented multifocal corrections.
[So] Source:Ophthalmic Physiol Opt;37(5):610-623, 2017 Sep.
[Is] ISSN:1475-1313
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:PURPOSE: Evaluate the importance of orientation of multifocal lens designs with angular increments of addition. METHODS: Optical properties of one monofocal and three multifocal designs were analysed with the visual Strehl ratio (VSOTF) metric through-focus (-1 to 5 D). Designs were tested in combination with the higher-order aberrations (HOAs) of 782 subjects (1564 eyes). Simulations included one monofocal, one bifocal (eight orientations), one trifocal (four orientations), and a 4-foci design (four orientations). Monocular and binocular performances of all designs were assessed by computing the area under the through-focus VSOTF plots, the through-focus range of acceptable optical performance, and, for binocular combinations, optical disparity between left and right eyes. RESULTS: Under monocular conditions, bifocal designs generated larger areas under the through focus VSOTF than trifocal designs and 4-foci designs. Specifically, bifocal designs divided vertically were optimal for 48% of eyes. Trifocal designs and 4-foci designs offered longer intervals of acceptable through-focus vision. Coma and spherical aberration values were correlated with the optimal orientation of multifocal corrections. The best binocular combination was achieved with a monofocal and a trifocal lens. The orientation of a multifocal design with angular areas affected the final optical properties of the combination (lens plus eye). CONCLUSIONS: The optical aberration distributions for our population of physiologically normal eyes demonstrated improved performance for some lens design orientations (i.e., left-right segments for 2-zone bifocals). Taking into account the HOAs of healthy patients, with special attention to coma and spherical aberration, will increase the optical quality of angularly divided multifocal solutions.
[Mh] Termos MeSH primário: Simulação por Computador
Sensibilidades de Contraste/fisiologia
Óculos
Refração Ocular/fisiologia
Erros de Refração/terapia
Acuidade Visual
[Mh] Termos MeSH secundário: Seres Humanos
Erros de Refração/fisiopatologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170929
[Lr] Data última revisão:
170929
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170825
[St] Status:MEDLINE
[do] DOI:10.1111/opo.12402


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[PMID]:28816865
[Au] Autor:Li Y; Bradley A; Xu R; Kollbaum PS
[Ad] Endereço:1School of Ophthalmology & Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China 2School of Optometry, Indiana University, Bloomington, Indiana.
[Ti] Título:Liquid Crystal Spatial Light Modulators for Simulating Zonal Multifocal Lenses.
[So] Source:Optom Vis Sci;94(9):867-875, 2017 Sep.
[Is] ISSN:1538-9235
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:SIGNIFICANCE: To maximize efficiency of the normally lengthy and costly multizone lens design and testing process, it is advantageous to evaluate the potential efficacy of a design as thoroughly as possible prior to lens fabrication and on-eye testing. The current work describes an ex vivo approach of optical design testing. PURPOSE: The aim of this study was to describe a system capable of examining the optical characteristics of multizone bifocal and multifocal optics by subaperture stitching using liquid crystal technologies. METHODS: A liquid crystal spatial light modulator (SLM) was incorporated in each of two channels to generate complementary subapertures by amplitude modulation. Additional trial lenses and phase plates were placed in pupil conjugate planes of either channel to integrate the desired bifocal and multifocal optics once the two optical paths were recombined. A high-resolution Shack-Hartmann aberrometer was integrated to measure the optics of the dual-channel system. Power and wavefront error maps as well as point spread functions were measured and computed for each of three multizone multifocal designs. RESULTS: High transmission modulation was achieved by introducing half-wavelength optical path differences to create two- and five-zone bifocal apertures. Dual-channel stitching revealed classic annular rings in the point spread functions generated from two-zone designs when the outer annular optic was defocused. However, low efficiency of the SLM prevented us from simultaneously measuring the eye + simulator aberrations, and the higher-order diffraction patterns generated by the cellular structure of the liquid crystal arrays limited the visual field to ±0.45 degrees. CONCLUSIONS: The system successfully simulated bifocal and multifocal simultaneous lenses allowing for future evaluation of both objective and subjective evaluation of complex optical designs. However, low efficiency and diffraction phenomena of the SLM limit the utility of this technology for simulating multizone and multifocal optics.
[Mh] Termos MeSH primário: Óculos
Luz
Cristais Líquidos
Óptica e Fotônica
Pupila/fisiologia
[Mh] Termos MeSH secundário: Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170919
[Lr] Data última revisão:
170919
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170818
[St] Status:MEDLINE
[do] DOI:10.1097/OPX.0000000000001108


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[PMID]:28756152
[Au] Autor:Mantagos IS; Kleinman ME; Kieran MW; Gordon LB
[Ad] Endereço:Department of Ophthalmology, Boston Children's Hospital - Harvard Medical School, Boston, Massachusetts. Electronic address: Jason.Mantagos@childrens.harvard.edu.
[Ti] Título:Ophthalmologic Features of Progeria.
[So] Source:Am J Ophthalmol;182:126-132, 2017 Oct.
[Is] ISSN:1879-1891
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PURPOSE: To establish the natural history of ophthalmic characteristics in Progeria patients and to determine incidence of ocular manifestations. DESIGN: Retrospective case series of patients with Progeria who were seen between 2007 and 2016. METHODS: Setting: Tertiary-care academic center. PATIENT POPULATION: Fourteen patients (28 eyes) with Hutchinson-Gilford Progeria syndrome were included for statistical analysis from a total of 84 patients who have been enrolled in clinical trials for Progeria at Boston Children's Hospital. Clinical treatment trial patients who were not seen at the Department of Ophthalmology at our hospital, but for whom we had detailed clinical ophthalmologic records, were also included. This essentially represents an estimated 20% of the world's known patients with Progeria. Interventions or Observation Procedures: Complete ophthalmic examination. MAIN OUTCOME MEASURES: Visual acuity, stereoacuity, refraction, clinical findings of slit-lamp and dilated fundus examinations. RESULTS: Ophthalmic manifestations noted were hyperopia and signs of ocular surface disease owing to nocturnal lagophthalmos and exposure keratopathy. Additional ophthalmic manifestations included reduced brow hair, madarosis, and reduced accommodation. Most patients had relatively good acuity; however, advanced ophthalmic disease was associated with reduced acuity. CONCLUSIONS: Children with Progeria are at risk for serious ophthalmic complications owing to ocular surface disease. Children with Progeria should have an ophthalmic evaluation at the time of diagnosis and at least yearly after that. Aggressive ocular surface lubrication is recommended, including the use of tape tarsorrhaphy at night.
[Mh] Termos MeSH primário: Oftalmopatias/diagnóstico
Progéria/diagnóstico
[Mh] Termos MeSH secundário: Adolescente
Criança
Pré-Escolar
Doenças da Córnea/diagnóstico
Oftalmopatias/fisiopatologia
Oftalmopatias/terapia
Sobrancelhas/patologia
Óculos/utilização
Doenças Palpebrais/diagnóstico
Feminino
Seguimentos
Seres Humanos
Masculino
Progéria/fisiopatologia
Progéria/terapia
Refração Ocular/fisiologia
Estudos Retrospectivos
Acuidade Visual/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171003
[Lr] Data última revisão:
171003
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170731
[St] Status:MEDLINE



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