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[PMID]: 29273016 [Au] Autor: Nam SW; Lim DH; Hyun J; Chung ES; Chung TY [Ad] Endereço: Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, #81 Irwon-ro, Gangnam-gu, Seoul, 06351, South Korea. [Ti] Título: Buffering zone of implantable Collamer lens sizing in V4c. [So] Source: BMC Ophthalmol;17(1):260, 2017 Dec 22. [Is] ISSN: 1471-2415 [Cp] País de publicação: England [La] Idioma: eng [Ab] Resumo: BACKGROUND: The purpose of this study was to identify factors related to the unexpected vault in V4c implantable collamer lens (ICL; STAAR Surgical) implantation. METHODS: V4c ICLs were implanted in 43 eyes of 43 patients for the correction of myopia. The implanted V4c ICL sizes were determined individually with our previous V4 ICL sizing nomogram based on the sulcus-to-sulcus diameter (STS), and the V4 ICL sizes were then converted to V4c ICL sizes with a size-converting table. We defined the "normal-sizing group" as having a pre-converted ICL size larger than the STS, and the "under-sizing group" as having a pre-converted ICL size smaller than the STS. Refractive outcomes, safety and parameters related to postoperative vault were compared between the two groups. RESULTS: The value of "actual ICL size - STS" differed significantly between the normal-sizing and under-sizing groups (p < 0.001), but postoperative vault did not differ significantly (p = 0.442). The demographics, implanted ICL characteristics, effectiveness indexes, safety indexes, and parameters related to postoperative vault did not differ significantly between the two groups (p > 0.05). Two patients in the normal-sizing group exhibited over-vaulting; these patients had shallow anterior chambers and were implanted with high-dioptric-power ICLs. CONCLUSIONS: The achievement of acceptable vault in both normal-sizing and under-sizing groups indicates the existence of a buffering zone in V4c ICL sizing. The smaller size of V4c ICLs should be considered in patients susceptible to over-vaulting, such as those with shallow anterior chambers and high-dioptric-power ICLs. [Mh] Termos MeSH primário: Miopia/cirurgia Lentes Intraoculares Fácicas Refração Ocular/fisiologia Acuidade Visual [Mh] Termos MeSH secundário: Adolescente Adulto Feminino Seguimentos Seres Humanos Implante de Lente Intraocular Masculino Meia-Idade Miopia/fisiopatologia Desenho de Prótese Estudos Retrospectivos Fatores de Tempo Resultado do Tratamento Testes Visuais Adulto Jovem [Pt] Tipo de publicação: JOURNAL ARTICLE [Em] Mês de entrada: 1802 [Cu] Atualização por classe: 180228 [Lr] Data última revisão: 180228 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 171224 [St] Status: MEDLINE [do] DOI: 10.1186/s12886-017-0663-4

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[PMID]: 29208843 [Au] Autor: Galvis V; Carreño NI; Tello A; Laiton AN [Ad] Endereço: Centro Oftalmológico Virgilio Galvis, Floridablanca; Department of Ophthalmology, Faculty of Health Sciences, Universidad Autónoma de Bucaramanga, Bucaramanga; Department of Ophthalmology, Fundación Oftalmológica de Santander FOSCAL, Floridablanca, Colombia. [Ti] Título: Severe pigment dispersion after iris-claw phakic intraocular lens implantation. [So] Source: Indian J Ophthalmol;65(12):1492-1494, 2017 Dec. [Is] ISSN: 1998-3689 [Cp] País de publicação: India [La] Idioma: eng [Ab] Resumo: A 23-year-old female patient presented 3 months after the implantation of an Artisan® phakic intraocular lens with a severe depigmentation of the iris and peripheral anterior synechiae. Explantation of the intraocular lens and goniosynechialysis were performed. Eleven months after the explantation appearance of the iris significantly improved. There was no loss of lines of corrected distance visual acuity. Severe pigment dispersion after the implantation of an Artisan® phakic intraocular lens may happen and may require explantation of the lens. Iris depigmentation may improve with time. [Mh] Termos MeSH primário: Síndrome de Exfoliação/etiologia Iris/patologia Lentes Intraoculares Fácicas/efeitos adversos Complicações Pós-Operatórias Acuidade Visual [Mh] Termos MeSH secundário: Síndrome de Exfoliação/diagnóstico Feminino Seres Humanos Iris/cirurgia Desenho de Prótese Índice de Gravidade de Doença Adulto Jovem [Pt] Tipo de publicação: CASE REPORTS; JOURNAL ARTICLE [Em] Mês de entrada: 1712 [Cu] Atualização por classe: 180103 [Lr] Data última revisão: 180103 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 171207 [St] Status: MEDLINE [do] DOI: 10.4103/ijo.IJO_743_17

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[PMID]: 28846701 [Au] Autor: Hyun J; Lim DH; Eo DR; Hwang S; Chung ES; Chung TY [Ad] Endereço: Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea. [Ti] Título: A comparison of visual outcome and rotational stability of two types of toric implantable collamer lenses (TICL) : V4 versus V4c. [So] Source: PLoS One;12(8):e0183335, 2017. [Is] ISSN: 1932-6203 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: PURPOSE: To compare the efficacy and rotational stability after implantation of two types of toric implantable collamer lenses (Toric ICL™(TICL);V4 and V4c, STAAR Surgical Co.). STUDY DESIGN: Retrospective case series. METHODS: This retrospective study evaluated total 48 eyes of 48 patients who underwent the implantation with V4 and V4c TICL with a central hole; A twenty-four eyes of 24 patients with V4 TICL and 24 eyes of 24 patients with V4c TICL with a central hole. Visual acuity, manifest refraction, and intraocular pressure were evaluated before and after surgery. Rotational stability (disparity between the intended axis and achieved axis) was assessed in both groups using digital anterior segment photographs, and vector analysis was also performed. RESULTS: Uncorrected visual acuity improved in both groups without significant difference (P = .111). There were no statistical differences between two groups in postoperative SE and cylindrical errors (P = .067 and .384, respectively). The mean value of rotation was 4.17±3.31° and 3.39±2.36° in the V4 and V4c TICL groups, respectively without significant difference (P = .364). Vector analysis of astigmatic correction showed no significant diffrence between two groups. CONCLUSION: V4 and V4c TICL have similar efficacy with regard to visual acuity and refractive outcomes and rotational stability. [Mh] Termos MeSH primário: Astigmatismo/cirurgia Implante de Lente Intraocular Lentes Intraoculares Fácicas Acuidade Visual/fisiologia [Mh] Termos MeSH secundário: Adolescente Adulto Feminino Seres Humanos Masculino Meia-Idade Estudos Retrospectivos Rotação Resultado do Tratamento Testes Visuais Adulto Jovem [Pt] Tipo de publicação: JOURNAL ARTICLE [Em] Mês de entrada: 1710 [Cu] Atualização por classe: 171019 [Lr] Data última revisão: 171019 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170829 [St] Status: MEDLINE [do] DOI: 10.1371/journal.pone.0183335

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[PMID]: 28774525 [Au] Autor: Eissa SA; El-Deeb MW; Hendawi MS [Ad] Endereço: Ophthalmology, Cairo University, and Ophthalmology and Refractive Surgery, Magrabi Hospital, Khamis Mushait, Kingdom of Saudi Arabia; Ophthalmology Department, Kasr Al Ainy, Cairo University, Egypt. [Ti] Título: V4B implantable collamer lens versus Intacs corneal rings to manage anisometropic myopic amblyopia in children. [So] Source: Can J Ophthalmol;52(4):409-415, 2017 Aug. [Is] ISSN: 1715-3360 [Cp] País de publicação: England [La] Idioma: eng [Ab] Resumo: OBJECTIVE: To compare the safety and efficacy of phakic intraocular lens (PIOL) versus intrastromal corneal ring segments (Intacs), for correcting high myopic anisometropia in amblyopic children. DESIGN: Nonrandomized prospective multi-center study. PARTICIPANTS: Thirty children, aged between 4 and 12 years, with unilateral high myopic anisometropic amblyopia were included in this study. METHODS: Patients who were prospectively subdivided into group A, with mean preoperative manifest refraction spherical equivalent (MRSE) of -12.96 ± 4.17 D, underwent unilateral phakic posterior chamber intraocular lens implantation. Patients with mean preoperative MRSE of -8.60 ± 1.16 D in group B were treated by Intacs corneal rings. Pre- and postoperative visual acuity, ocular examination, stereoacuity, axial biometry measurements, cycloplegic refraction, and endothelial cell counts were performed in all patients. RESULTS: Group A revealed prevention of amblyopia with improvement in spectacle-corrected distance visual acuity, where 4-6 lines were achieved in 77% of children, 2-3 lines in 4%, and just 0-1 lines restricted to 19% of children. Improvement in stereoacuity was noted in 93.33% of group A cases, whereas group B showed fewer cases of successfully improved vision, with 4-6 lines in 70% of children, 2-3 lines in 3%, and just 0-1 lines restricted to 27% of children. Improvement in stereoacuity was noted in 86.66% of cases. Two cases of cataract and 1 case of glaucoma with 1 case of uveitis were noted in the implantable contact lens (ICL) group. CONCLUSIONS: Posterior chamber PIOLs or Intacs may provide a safe alternative in treating anisometropic myopic patients. Intacs implantation is safer with fewer complications than ICL. However, ICL implantation is advantageous over the corneal ring segment procedure owing to the wide range of errors to correct. [Mh] Termos MeSH primário: Ambliopia/cirurgia Anisometropia/cirurgia Córnea/cirurgia Implante de Lente Intraocular/métodos Miopia/cirurgia Lentes Intraoculares Fácicas Refração Ocular/fisiologia [Mh] Termos MeSH secundário: Ambliopia/complicações Ambliopia/fisiopatologia Anisometropia/complicações Anisometropia/fisiopatologia Criança Pré-Escolar Feminino Seguimentos Seres Humanos Masculino Miopia/complicações Miopia/fisiopatologia Estudos Prospectivos Desenho de Prótese Resultado do Tratamento Acuidade Visual [Pt] Tipo de publicação: JOURNAL ARTICLE [Em] Mês de entrada: 1711 [Cu] Atualização por classe: 171102 [Lr] Data última revisão: 171102 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170805 [St] Status: MEDLINE

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[PMID]: 28662940 [Au] Autor: Fernández-Vigo JI; Macarro-Merino A; Fernández-Vigo C; Fernández-Vigo JÁ; De-Pablo-Gómez-de-Liaño L; Fernández-Pérez C; García-Feijóo J [Ad] Endereço: Department of Ophthalmology, Hospital Clínico San Carlos and Instituto de Investigación Sanitaria San Carlos, Madrid, Spain; Centro Internacional de Oftalmología Avanzada, Madrid, Spain. Electronic address: jfvigo@hotmail.com. [Ti] Título: Impacts of Implantable Collamer Lens V4c Placement on Angle Measurements Made by Optical Coherence Tomography: Two-Year Follow-up. [So] Source: Am J Ophthalmol;181:37-45, 2017 Sep. [Is] ISSN: 1879-1891 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: PURPOSE: To determine iridocorneal angle changes produced after 2 years of implantable collamer lens (ICL) V4c (STAAR Surgical AG, Nidau, Switzerland) placement by Fourier-domain optical coherence tomography (FD-OCT). DESIGN: Prospective interventional case series. METHODS: In 54 eyes of 27 myopic subjects FD-OCT iridocorneal angle measurements were made before and 1 month, 3 months, 1 year, and 2 years after ICL implant. Trabecular-iris angle (TIA), angle opening distance 500 µm from the scleral spur (AOD ), and iridotrabecular contact length (TICL) were compared among these time points and the nasal, temporal, and inferior quadrants. RESULTS: Preoperative TIAs were 49.5 ± 8.7, 48.3 ± 9.6, and 49.1 ±8.6 degrees for the nasal, temporal and inferior quadrants (P < .001). Corresponding values were 29.9 ± 10.4, 28.4 ± 10.8, and 28.8 ± 9.7 degrees at 1 month and 27.3 ± 8.8, 26.8 ± 8.1, and 28.9 ± 7 degrees at 2 years of follow-up, indicating angle narrowing of 39%-45% and no further narrowing beyond 1 month in the nasal (P = .133), temporal (P = .376), and inferior (P = 1.000) quadrants. Trabecular-iris contact (TIC) was observed in 8 eyes of 8 subjects, mostly only in the temporal quadrant. Mean TICL failed to vary during follow-up (307 ± 288 µm at 3 months and 225 ± 142 µm at 2 years, P = .159). CONCLUSIONS: In response to ICL V4c implant, considerable angle narrowing was detected at 1 month but this narrowing remained stable at 2 years. In the 8 cases of TIC, no progression of contact was observed beyond 3 months postimplant. [Mh] Termos MeSH primário: Câmara Anterior/patologia Córnea/patologia Iris/patologia Implante de Lente Intraocular Miopia/cirurgia Lentes Intraoculares Fácicas [Mh] Termos MeSH secundário: Adulto Câmara Anterior/diagnóstico por imagem Córnea/diagnóstico por imagem Feminino Seguimentos Análise de Fourier Seres Humanos Iris/diagnóstico por imagem Masculino Estudos Prospectivos Tomografia de Coerência Óptica Malha Trabecular/diagnóstico por imagem Malha Trabecular/patologia Acuidade Visual/fisiologia Adulto Jovem [Pt] Tipo de publicação: JOURNAL ARTICLE [Em] Mês de entrada: 1709 [Cu] Atualização por classe: 170911 [Lr] Data última revisão: 170911 [Sb] Subgrupo de revista: AIM; IM [Da] Data de entrada para processamento: 170701 [St] Status: MEDLINE

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[PMID]: 28650856 [Au] Autor: Grover IG; Senthil S; Murthy S; Reddy JC [Ad] Endereço: LV Prasad Eye Institute, Hyderabad, India. [Ti] Título: A Rare Case of Pupillary Block Glaucoma Following CentraFLOW Implantable Collamer Lens Surgery. [So] Source: J Glaucoma;26(8):694-696, 2017 Aug. [Is] ISSN: 1536-481X [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: A 28-year-old lady with a refractive error of -11.0 D sphere/-1.50 D cylinder at 160 degrees in the right eye underwent an uneventful Implantable Collamer Lens surgery (ICL) with a V4c model, which uses a central Aquaport. This ICL does not require preoperative laser iridotomy or surgical iridectomy, as the centraflow opening is designed to prevent pupillary block. At postoperative day 1, her visual acuity in the right eye was 20/400, with diffuse microcystic corneal edema with fixed, dilated pupil and high intraocular pressure. Following intravenous mannitol, the corneal edema resolved. It was then noted that the ICL was anteriorly displaced, creating acute pupillary block, presumably due to obstruction of the central Aquaport with viscoelastic and inflammatory debris. She underwent AC wash the same day that helped in IOP control; however, the pupil remained permanently dilated and fixed because of extensive sphincter atrophy as a result of acute pupillary block. By 1 month, the visual acuity was 20/30 with an IOP of 14 mm Hg, which was maintained at 1-year follow-up. We report the first case of pupillary block glaucoma with this particular ICL design, suggesting the need for careful attention to complete removal of viscoelastic in the anterior chamber and behind the ICL, to prevent such complications and their cosmetically unacceptable sequelae. [Mh] Termos MeSH primário: Glaucoma de Ângulo Fechado/etiologia Implante de Lente Intraocular/efeitos adversos Lentes Intraoculares Fácicas/efeitos adversos Distúrbios Pupilares/etiologia [Mh] Termos MeSH secundário: Adulto Edema da Córnea/etiologia Feminino Glaucoma de Ângulo Fechado/fisiopatologia Seres Humanos Pressão Intraocular/fisiologia Iridectomia Cristalino Miopia/cirurgia Distúrbios Pupilares/fisiopatologia Acuidade Visual/fisiologia [Pt] Tipo de publicação: CASE REPORTS; JOURNAL ARTICLE [Em] Mês de entrada: 1711 [Cu] Atualização por classe: 171106 [Lr] Data última revisão: 171106 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170627 [St] Status: MEDLINE [do] DOI: 10.1097/IJG.0000000000000705

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[PMID]: 28557825 [Au] Autor: Tognetto D; De Giacinto C; Cirigliano G [Ad] Endereço: Eye Clinic, University of Trieste, Trieste, Italy. [Ti] Título: Suture of Symptomatic YAG Laser Peripheral Iridotomies Following Phakic Intraocular Lens Implantation. [So] Source: J Glaucoma;26(7):675-677, 2017 Jul. [Is] ISSN: 1536-481X [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: A 45-year-old woman complained of glare and photophobia after iris-fixated phakic intraocular lens (IFPIOL) implantation in her left eye. The patient underwent prophylactic laser peripheral iridotomies (LPIs) 2 days before surgery. The uncorrected visual acuity after surgery was 20/20 and the intraocular pressure was 14 mm Hg. The slit-lamp examination showed a well-centered IFPIOL and 2 LPIs at 10 and 2 o'clock partially covered by the upper lid. Twenty days after IFPIOL implantation, as symptoms persisted and were intolerable to the patient, we decide to suture iridotomies using a modified Siepser slip-knot technique. Postoperatively, visual acuity remains 20/20 and patient reported a complete disappearance of symptoms. No intraoperative and postoperative complications were noted. Experiencing glare and photophobia is a rare side effect due to LPI. Suture of iridotomies using a modified Siepser slip-knot technique can be considered a safe and effective procedure to solve this annoying complication. [Mh] Termos MeSH primário: Iridectomia Iris/cirurgia Lasers de Estado Sólido/uso terapêutico Implante de Lente Intraocular Lentes Intraoculares Fácicas Técnicas de Sutura [Mh] Termos MeSH secundário: Feminino Seres Humanos Pressão Intraocular Terapia a Laser/métodos Meia-Idade Miopia/complicações Acuidade Visual [Pt] Tipo de publicação: CASE REPORTS; JOURNAL ARTICLE [Em] Mês de entrada: 1710 [Cu] Atualização por classe: 171024 [Lr] Data última revisão: 171024 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170531 [St] Status: MEDLINE [do] DOI: 10.1097/IJG.0000000000000688

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[PMID]: 28432184 [Au] Autor: Kumar A; Mehta A; Ravani RD; Kakkar P [Ad] Endereço: Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India. [Ti] Título: Management of a case of myopic foveoschisis with phakic intraocular lens (pIOL) in situ: intraoperative challenges. [So] Source: BMJ Case Rep;2017, 2017 Apr 20. [Is] ISSN: 1757-790X [Cp] País de publicação: England [La] Idioma: eng [Ab] Resumo: We describe the case of a 30-year-old man with pathological myopia with a phakic intraocular lens (IOL) (Visian ICL V4c model; STAAR, Monrovia, California, USA) in situ having complaints of metamorphopsia in the left eye with documented myopic foveoschisis on swept-source optical coherence tomography (DRI OCT Triton; Topcon, Tokyo, Japan). The patient underwent pars plana vitrectomy with internal limiting membrane peeling. This report discusses the intraoperative challenges occurring as a result of increased optical aberrations in the presence of a phakic IOL. [Mh] Termos MeSH primário: Miopia Degenerativa/cirurgia Retinosquise/diagnóstico por imagem [Mh] Termos MeSH secundário: Adulto Seres Humanos Masculino Lentes Intraoculares Fácicas Retinosquise/cirurgia Tomografia de Coerência Óptica Resultado do Tratamento [Pt] Tipo de publicação: CASE REPORTS; JOURNAL ARTICLE [Em] Mês de entrada: 1706 [Cu] Atualização por classe: 170628 [Lr] Data última revisão: 170628 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170423 [St] Status: MEDLINE

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[PMID]: 28342721 [Au] Autor: Lu Y; Yang N; Li X; Kong J [Ad] Endereço: Department of Ophthalmology, The Fourth Affiliated Hospital of China Medical University, Provincial Key Laboratory of Lens Research, Shenyang, China. [Ti] Título: Four-year Follow-up of the Changes in Anterior Segment After Phakic Collamer Lens Implantation. [So] Source: Am J Ophthalmol;178:140-149, 2017 Jun. [Is] ISSN: 1879-1891 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: PURPOSE: To assess the changes and relationship in central vaulting, flare intensity, and crystalline lens thickness during a follow-up period of 4 years after implantable collamer lens (ICL) implantation in eyes with high myopia. DESIGN: Retrospective observational study. METHODS: Ninety-eight eyes of 50 patients were followed up with routine measurements of central vaulting, crystalline lens thickness, endothelial cell density, and aqueous flare postoperatively. Data were analyzed by repeated-measures analysis of variance. The relationship between the annual change in crystal lens thickness after surgery and age was evaluated by Pearson correlation coefficient and linear regression. RESULTS: There was a continuous reduction in central vaulting and endothelial cell density as well as an increase in crystalline lens thickness in ICL eyes from 1 month onward to 5 years postoperatively (P < .001). Although the trend of variation during the individual visit period was accentuated, the variation turned out to be smaller between 12 and 36 months or 60 months postoperatively (P = .42, P = .65). Aqueous flare intensity increased significantly after surgery and returned to normal 1 year later. Additionally, a positive correlation between patient age and crystalline lens thickness (r = 0.617, P < .0001) was observed in eyes with ICL implantation. CONCLUSIONS: The changes in central vaulting, endothelial cell density, and crystalline lens thickness are more prominent during the first year after ICL implantation, tending to be relatively stable afterwards. The anterior inflammation during the early postoperative period synchronizes with the sharp progression of crystalline lens changes within the first year. [Mh] Termos MeSH primário: Segmento Anterior do Olho/diagnóstico por imagem Cristalino/diagnóstico por imagem Miopia/cirurgia Lentes Intraoculares Fácicas Refração Ocular/fisiologia Tomografia de Coerência Óptica/métodos Acuidade Visual [Mh] Termos MeSH secundário: Adulto Contagem de Células Epitélio Posterior/patologia Feminino Seguimentos Seres Humanos Masculino Meia-Idade Miopia/diagnóstico Miopia/fisiopatologia Estudos Retrospectivos Fatores de Tempo Adulto Jovem [Pt] Tipo de publicação: JOURNAL ARTICLE; OBSERVATIONAL STUDY [Em] Mês de entrada: 1707 [Cu] Atualização por classe: 170721 [Lr] Data última revisão: 170721 [Sb] Subgrupo de revista: AIM; IM [Da] Data de entrada para processamento: 170327 [St] Status: MEDLINE

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[PMID]: 28292776 [Au] Autor: Goukon H; Kamiya K; Shimizu K; Igarashi A [Ad] Endereço: Department of Ophthalmology, University of Kitasato School of Medicine, Kanagawa, Japan. [Ti] Título: Comparison of corneal endothelial cell density and morphology after posterior chamber phakic intraocular lens implantation with and without a central hole. [So] Source: Br J Ophthalmol;101(11):1461-1465, 2017 Nov. [Is] ISSN: 1468-2079 [Cp] País de publicação: England [La] Idioma: eng [Ab] Resumo: AIM: To compare the corneal endothelial cells after posterior chamber phakic intraocular lens with and without a central hole (hole implantable collamer lens (ICL) and conventional ICL) implantation for the correction of moderate to high myopia. METHODS: This retrospective study evaluated 34 eyes of 34 patients who underwent hole ICL implantation and 25 eyes of 25 patients who underwent conventional ICL implantation. Preoperatively and 3 months, and 1 and 2 years postoperatively, we compared the central corneal endothelial cell density (ECD), coefficient of variation in cell size (CV) and the percentage of hexagonal cells (HEX) between the two groups using a non-contact specular microscope (EM-3000, Tomey). Preoperatively and 2 years postoperatively, we also compared them in the peripheral regions. RESULTS: The mean central ECD loss was 0.3% and 1.1%, 2 years after hole ICL and conventional ICL implantation, respectively (Mann-Whitney U test, p=0.72). There were no significant changes in central ECD, CV or HEX at any time points either after hole ICL or conventional ICL implantation, and a significant decrease only in terms of ECD in the superior regions after conventional ICL implantation. CONCLUSIONS: Both ICLs do not induce a significant change in the density, polymegethism or polymorphism of corneal endothelial cells even 2 years postoperatively, except for the density in the superior regions after conventional ICL implantation. However, hole ICL implantation may have advantages over conventional ICL implantation only in terms of the density in the superior regions, possibly because preoperative laser iridotomies are unnecessary. [Mh] Termos MeSH primário: Epitélio Posterior/patologia Implante de Lente Intraocular/métodos Miopia/cirurgia Lentes Intraoculares Fácicas Segmento Posterior do Olho/cirurgia [Mh] Termos MeSH secundário: Adulto Contagem de Células Feminino Seguimentos Seres Humanos Masculino Meia-Idade Miopia/patologia Desenho de Prótese Estudos Retrospectivos Fatores de Tempo Acuidade Visual Adulto Jovem [Pt] Tipo de publicação: COMPARATIVE STUDY; JOURNAL ARTICLE [Em] Mês de entrada: 1711 [Cu] Atualização por classe: 171102 [Lr] Data última revisão: 171102 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170316 [St] Status: MEDLINE [do] DOI: 10.1136/bjophthalmol-2016-309363

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