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[PMID]:28741663
[Au] Autor:Stehouwer MC; de Vroege R; Hoohenkerk GJF; Hofman FN; Kelder JC; Buchner B; de Mol BA; Bruins P
[Ad] Endereço:Department of Extracorporeal Circulation, St Antonius Hospital, Nieuwegein, The Netherlands.
[Ti] Título:Carbon Dioxide Flush of an Integrated Minimized Perfusion Circuit Prior to Priming Prevents Spontaneous Air Release Into the Arterial Line During Clinical Use.
[So] Source:Artif Organs;41(11):997-1003, 2017 Nov.
[Is] ISSN:1525-1594
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Recently, an oxygenator with an integrated centrifugal blood pump (IP) was designed to minimize priming volume and to reduce blood foreign surface contact even further. The use of this oxygenator with or without integrated arterial filter was compared with a conventional oxygenator and nonintegrated centrifugal pump. To compare the air removal characteristics 60 patients undergoing coronary artery bypass grafting were alternately assigned into one of three groups to be perfused with a minimized extracorporeal circuit either with the conventional oxygenator, the oxygenator with IP, or the oxygenator with IP plus integrated arterial filter (IAF). Air entering and leaving the three devices was measured accurately with a bubble counter during cardiopulmonary bypass. No significant differences between all groups were detected, considering air entering the devices. Our major finding was that in both integrated devices groups incidental spontaneous release of air into the arterial line in approximately 40% of the patients was observed. Here, detectable bolus air (>500 µm) was shown in the arterial line, whereas in the minimal extracorporeal circulation circuit (MECC) group this phenomenon was not present. We decided to conduct an amendment of the initial design with METC-approval. Ten patients were assigned to be perfused with an oxygenator with IP and IAF. Importantly, the integrated perfusion systems used in these patients were flushed with carbon dioxide (CO ) prior to priming of the systems. In the group with CO flush no spontaneous air release was observed in all cases and this was significantly different from the initial study with the group with the integrated device and IAF. This suggests that air spilling may be caused by residual air in the integrated device. In conclusion, integration of a blood pump may cause spontaneous release of large air bubbles (>500 µm) into the arterial line, despite the presence of an integrated arterial filter. CO flushing of an integrated cardiopulmonary bypass system prior to priming may prevent spontaneous air release and is strongly recommended to secure patient safety.
[Mh] Termos MeSH primário: Dióxido de Carbono
Ponte Cardiopulmonar/instrumentação
Cateteres
Ponte de Artéria Coronária
Embolia Aérea/prevenção & controle
Oxigenação por Membrana Extracorpórea/instrumentação
Coração Auxiliar
Oxigenadores
Perfusão/instrumentação
[Mh] Termos MeSH secundário: Idoso
Idoso de 80 Anos ou mais
Ponte Cardiopulmonar/efeitos adversos
Ponte de Artéria Coronária/efeitos adversos
Embolia Aérea/diagnóstico
Embolia Aérea/etiologia
Oxigenação por Membrana Extracorpórea/efeitos adversos
Feminino
Seres Humanos
Masculino
Meia-Idade
Perfusão/efeitos adversos
Desenho de Prótese
Resultado do Tratamento
[Pt] Tipo de publicação:CLINICAL TRIAL; COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Nome de substância:
142M471B3J (Carbon Dioxide)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180129
[Lr] Data última revisão:
180129
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170726
[St] Status:MEDLINE
[do] DOI:10.1111/aor.12909


  2 / 907 MEDLINE  
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[PMID]:28093810
[Au] Autor:Duncan DR; Kerins PJ
[Ad] Endereço:A.I. duPont Hospital for Children, 1600 Rockland Road, Wilmington, DE 19803 , USA.
[Ti] Título:A Hybrid Pediatric Cardiopulmonary Bypass Circuit for Complex Suprahepatic Inferior Vena Cava Reconstruction.
[So] Source:Artif Organs;41(1):107-108, 2017 Jan.
[Is] ISSN:1525-1594
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Ponte Cardiopulmonar/instrumentação
Veia Cava Inferior/cirurgia
[Mh] Termos MeSH secundário: Ponte Cardiopulmonar/métodos
Criança
Seres Humanos
Transplante de Fígado
Oxigenadores
Veia Cava Inferior/patologia
[Pt] Tipo de publicação:CASE REPORTS; LETTER
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170127
[Lr] Data última revisão:
170127
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170118
[St] Status:MEDLINE
[do] DOI:10.1111/aor.12902


  3 / 907 MEDLINE  
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[PMID]:27872272
[Au] Autor:Patvardhan C; Valchanov K
[Ad] Endereço:Papworth Hospital, Papworth Everard, Cambridge, UK.
[Ti] Título:Oxygenator failure in acute myeloid leukaemia. A case report.
[So] Source:Perfusion;32(4):333-335, 2017 May.
[Is] ISSN:1477-111X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Extracorporeal membrane oxygenation (ECMO) therapy can be used to rescue patients who develop respiratory failure with acute myeloid leukaemia. We describe a unique case of rapid failure of an oxygenator on ECMO, secondary to high leukocyte count and cell lysis in an adult patient with acute myeloid leukaemia.
[Mh] Termos MeSH primário: Oxigenação por Membrana Extracorpórea/métodos
Leucemia Mieloide Aguda/fisiopatologia
Oxigenadores
Insuficiência Respiratória/etiologia
Insuficiência Respiratória/terapia
[Mh] Termos MeSH secundário: Oxigenação por Membrana Extracorpórea/efeitos adversos
Seres Humanos
Masculino
Meia-Idade
Falha de Tratamento
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170822
[Lr] Data última revisão:
170822
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161123
[St] Status:MEDLINE
[do] DOI:10.1177/0267659116679882


  4 / 907 MEDLINE  
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[PMID]:27831999
[Au] Autor:Hohlfelder B; Szumita PM; Lagambina S; Weinhouse G; Degrado JR
[Ad] Endereço:From the *Department of Pharmacy Services, Brigham and Women's Hospital, Boston, Massachusetts; †Department of Respiratory Therapy, Brigham and Women's Hospital, Boston, Massachusetts; and ‡Department of Pulmonary Medicine, Brigham and Women's Hospital, Boston, Massachusetts.
[Ti] Título:Safety of Propofol for Oxygenator Exchange in Extracorporeal Membrane Oxygenation.
[So] Source:ASAIO J;63(2):179-184, 2017 Mar/Apr.
[Is] ISSN:1538-943X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The purpose of this analysis is to describe the safety of propofol administration in adult extracorporeal membrane oxygenation (ECMO) patients. We performed a prospective cohort analysis of patients using ECMO at Brigham and Women's Hospital between February 2013 and October 2015. Patients were included if they used ECMO for at least 48 hours. The major end-point of the analysis was the median oxygenator lifespan. Oxygenator exchanges were analyzed by the number of patients requiring an oxygenator exchange and the number of oxygenator exchanges per ECMO day. A priori analysis was performed by comparing the outcomes between patients who did and did not receive propofol during their ECMO course. During the study, 43 patients were included in the analysis. Sixteen patients used propofol during their ECMO course. There were 12 oxygenator exchanges during therapy. Oxygenator exchange occurred on 1.8% of ECMO days. The median oxygenator lifespan was 7 days. Patients who used propofol had a significantly longer oxygenator lifespan (p = 0.02). Among patients who received propofol, patients who required oxygenator exchange used a significantly lower median daily dose of propofol (p < 0.001). The use of propofol appears safe in ECMO with regards to oxygenator viability. Contrary to expected, oxygenator lifespan was significantly longer among patients who received propofol.
[Mh] Termos MeSH primário: Oxigenação por Membrana Extracorpórea/efeitos adversos
Oxigenadores
Propofol/efeitos adversos
[Mh] Termos MeSH secundário: Adulto
Feminino
Seres Humanos
Masculino
Meia-Idade
Estudos Prospectivos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
YI7VU623SF (Propofol)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171016
[Lr] Data última revisão:
171016
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161111
[St] Status:MEDLINE
[do] DOI:10.1097/MAT.0000000000000461


  5 / 907 MEDLINE  
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[PMID]:27782314
[Au] Autor:Okahara S; Soh Z; Miyamoto S; Takahashi H; Itoh H; Takahashi S; Sueda T; Tsuji T
[Ad] Endereço:Department of Medical Engineering, Faculty of Health Siences, Junshin Gakuen University.
[Ti] Título:A Novel Blood Viscosity Estimation Method Based on Pressure-Flow Characteristics of an Oxygenator During Cardiopulmonary Bypass.
[So] Source:Artif Organs;41(3):262-266, 2017 Mar.
[Is] ISSN:1525-1594
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:During cardiopulmonary bypass (CPB), blood viscosity conspicuously increases and decreases due to changes in hematocrit and blood temperature. Nevertheless, blood viscosity is typically not evaluated, because there is no technology that can provide simple, continuous, noncontact monitoring. We modeled the pressure-flow characteristics of an oxygenator in a previous study, and in that study we quantified the influence of viscosity on oxygenator function. The pressure-flow monitoring information in the oxygenator is derived from our model and enables the estimation of viscosity. The viscosity estimation method was proposed and investigated in an in vitro experiment. Three samples of whole bovine blood with different hematocrit levels (21.8, 31.0, and 39.8%) were prepared and perfused into the oxygenator. As the temperature changed from 37°C to 27°C, the mean inlet pressure (P ) and outlet pressure (P ) of the oxygenator and the flow (Q) and viscosity of the blood were measured. The estimated viscosity was calculated from the pressure gradient (ΔP = P - P ) and Q and was compared to the measured blood viscosity. A strong correlation was found between the two methods for all samples. Bland-Altman analysis revealed a mean bias of -0.0263 mPa.s, a standard deviation of 0.071 mPa.s, limits of agreement of -0.114-0.166 mPa.s, and a percent error of 5%. Therefore, this method is considered compatible with the torsional oscillation viscometer that has plus or minus 5% measurement accuracy. Our study offers the possibility of continuously estimating blood viscosity during CPB.
[Mh] Termos MeSH primário: Pressão Sanguínea
Viscosidade Sanguínea
Ponte Cardiopulmonar/instrumentação
Modelos Cardiovasculares
Oxigenadores
[Mh] Termos MeSH secundário: Animais
Velocidade do Fluxo Sanguíneo
Bovinos
Hematócrito
Valor Preditivo dos Testes
Reprodutibilidade dos Testes
Temperatura Ambiente
Fatores de Tempo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170321
[Lr] Data última revisão:
170321
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161104
[St] Status:MEDLINE
[do] DOI:10.1111/aor.12747


  6 / 907 MEDLINE  
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[PMID]:27632800
[Au] Autor:Pierrakos C; Collot V; Van Lieshout H; De Doncker M; Delcourt S; Gottignies P; Devriendt J; De Bels D
[Ad] Endereço:Department of Intensive Care Unit, Brugmann University Hospital, Université Libre de Bruxelles, Brussels, Belgium. Electronic address: charalmapos.pierrakos@chu-brugmann.be.
[Ti] Título:Injection of agitated saline to detect recirculation with transthoracic echocardiography during venovenous extracorporeal oxygenation: A pilot study.
[So] Source:J Crit Care;37:60-64, 2017 Feb.
[Is] ISSN:1557-8615
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PURPOSE: We assessed the security and efficiency of intravenously injected agitated saline in conjunction with transthoracic echocardiography to identify recirculation in patients supported with a venovenous extracorporeal membrane oxygenation (VV ECMO) device. MATERIALS AND METHODS: We injected agitated saline 4 consecutive times separated by an interval of 5 minutes in 2 patients supported by VV ECMO. In both patients, the drainage cannula was placed in the left femoral vein, and the return cannula was placed in the right internal jugular vein. Echocardiography was performed during the injection and until the bubbles disappeared. The security of the method was assessed by evaluating the mechanical function of the ECMO and the efficiency of the oxygenator. The value of this method was assessed by visualizing the increase of inferior vena cava's echogenicity as well as by measuring the time required for this change to occur after the injection of agitated saline at different ECMO output levels. RESULTS: We did not observe any change in ECMO, oxygenation function, or the hemodynamic status of patients after the 4 injections of agitated saline. The echogenicity of the inferior vena cava increased more rapidly as the ECMO's output increased. The recirculation phenomenon was noted even with low levels of ECMO output (<2 L/min). CONCLUSIONS: Transthoracic echocardiography in conjunction with agitated saline administration may be a safe and easily applicable method to evaluate a recirculation phenomenon in patients supported with VV ECMO.
[Mh] Termos MeSH primário: Ecocardiografia/métodos
Oxigenação por Membrana Extracorpórea/métodos
Veias Jugulares
Pneumonia/terapia
Síndrome do Desconforto Respiratório do Adulto/terapia
Choque Séptico/terapia
[Mh] Termos MeSH secundário: Idoso
Feminino
Hemodinâmica
Seres Humanos
Injeções Intravenosas
Masculino
Oxigenadores
Projetos Piloto
Cloreto de Sódio
Veia Cava Inferior
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
451W47IQ8X (Sodium Chloride)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170921
[Lr] Data última revisão:
170921
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160916
[St] Status:MEDLINE


  7 / 907 MEDLINE  
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[PMID]:27497463
[Au] Autor:Born F; Khaladj N; Pichlmaier M; Schramm R; Hagl C; Guenther SP
[Ti] Título:Potential impact of oxygenators with venous air trap on air embolism in veno-arterial Extracorporeal Life Support.
[So] Source:Technol Health Care;25(1):111-121, 2017.
[Is] ISSN:1878-7401
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Air embolism is a potentially fatal but underrecognized complication in Extracorporeal Life Support (ECLS). Oxygenators containing venous air traps have been developed to minimize the risk of air embolism in daily care. OBJECTIVE: We reproduced air embolism as occurring via a central venous catheter in an experimental setting to test the potential of oxygenators with and without venous bubble trap (VBT) to withhold air. METHODS: An in vitro ECLS circuit was created and a central venous catheter with a 3-way stopcock and a perforated male luer cap was inserted into the inflow line. Three different oxygenators with and without VBT and their capability to withhold air were examined. After 60 seconds of stable ECLS flow, the stopcock was opened towards the atmosphere for 3 minutes. Afterwards, air accumulation within the oxygenator was determined. RESULTS: Comparison of the total air entrapment showed a significant superiority of the oxygenators with VBT (p < 0.001). All oxygenators were able to partly withhold macro air boli, however, the capacity of oxygenators with VBT was higher. Passing through the oxygenator resulted in a reduction of microbubbles in all cases. CONCLUSIONS: Macro air emboli can be substantially reduced by usage of oxygenators that contain a VBT, whereas the capability to withhold microbubbles to a vast extent seems to depend on the intrinsic oxygenator's membrane.
[Mh] Termos MeSH primário: Embolia Aérea/prevenção & controle
Oxigenação por Membrana Extracorpórea/efeitos adversos
Oxigenação por Membrana Extracorpórea/instrumentação
Oxigenadores
[Mh] Termos MeSH secundário: Desenho de Equipamento
Seres Humanos
Fatores de Tempo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171010
[Lr] Data última revisão:
171010
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160807
[St] Status:MEDLINE
[do] DOI:10.3233/THC-161248


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[PMID]:27986695
[Au] Autor:Ratzlaff RA; Ripoll JG; Kassab LL; Diaz-Gomez JL
[Ad] Endereço:Department of Critical Care Medicine, Mayo Clinic's Campus in Florida, Jacksonville, Florida, USA.
[Ti] Título:Acute oxygenator failure: a new presentation of heparin-induced thrombocytopenia in a patient undergoing venovenous extracorporeal membrane oxygenation support.
[So] Source:BMJ Case Rep;2016, 2016 Dec 16.
[Is] ISSN:1757-790X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:A 58-year-old man with medical history of thrombocytopenia was admitted to an outside hospital for a 6-day history of worsening dyspnoea requiring mechanical ventilator support. He was transferred to our institution for extracorporeal membrane oxygenation (ECMO) given his refractory hypoxaemia. On arrival, H1N1 influenza virus was confirmed and all measures to improve oxygenation were ineffective. Thus, the decision was made to start venovenous (VV)-ECMO. Although a low baseline platelet count was recognised (60-70×10 /L), a sudden further decrease occurred (30×10 /L) and platelet transfusion was initiated. A substantial increase in the pressure across the ECMO oxygenator was identified, and the diagnosis of type II heparin-induced thrombocytopenia was suspected and confirmed. Heparin was discontinued, the oxygenator was exchanged and argatroban was used for anticoagulation. After 28 days on VV-ECMO support, the decision was made to withdraw organ support in conjunction with the patient and family wishes.
[Mh] Termos MeSH primário: Dispneia/terapia
Oxigenação por Membrana Extracorpórea/efeitos adversos
Heparina/efeitos adversos
Oxigenadores/efeitos adversos
Trombocitopenia/induzido quimicamente
[Mh] Termos MeSH secundário: Anticoagulantes/efeitos adversos
Falha de Equipamento
Oxigenação por Membrana Extracorpórea/instrumentação
Seres Humanos
Masculino
Meia-Idade
Oxigênio/sangue
Trombocitopenia/sangue
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anticoagulants); 9005-49-6 (Heparin); S88TT14065 (Oxygen)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170309
[Lr] Data última revisão:
170309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161218
[St] Status:MEDLINE


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[PMID]:27626258
[Au] Autor:Bazylev VV; Evdokimov ME; Pantiukhina MA; Morozov ZA
[Ad] Endereço:Federal Centre of Cardiovascular Surgery under the RF Public Health Ministry, Penza, Russia.
[Ti] Título:[Artificial circulation in high-risk percutaneous coronary interventions].
[Ti] Título:Iskusstvennoe krovoobrashchenie pri chreskozhnykh koronarnykh vmeshatel'stvakh vysokogo riska..
[So] Source:Angiol Sosud Khir;22(3):112-9, 2016.
[Is] ISSN:1027-6661
[Cp] País de publicação:Russia (Federation)
[La] Idioma:rus
[Ab] Resumo:In their everyday practical clinical work cardiovascular surgeons sometimes have to deal with patients at extremely high risk of both percutaneous coronary interventions (PCIs) and direct myocardial revascularization. A method of choice in such situations may become a PCI supported by artificial circulation (AC), for which foreign and Russian authors propose using systems of prolonged extracorporeal membrane oxygenation (ECMO). The present work was aimed at sharing our experience with using standard systems of AC and their modifications (mini-circuit systems) for performing high-risk PCIs. Between October 2011 and November 2014, PCIs supported by artificial circulation were performed in a total of ten patients. All had extremely high risk of PCI due to coronary artery lesions [subocclusion of the trunk of the left coronary artery (LCA) combined with occlusion or significant stenosis of the right coronary artery (RCA)], concomitant pathology (obesity, diabetes mellitus, age, etc.) or critical state (circulatory arrest, resuscitating measures). Three patients during PCI developed ventricular fibrillation and one patient suffered an episode of asystole. All cardiac arrhythmias after restoration of the coronary blood flow disappeared spontaneously on the background of extracorporeal support. The only lethal outcome was registered during emergency PCI in a female patient admitted to the roentgen-operating room in the state of clinical death, on the background of continuing resuscitation measures. The presented methods of assisted circulation based on the standard AC systems and modification thereof (mini-circuit system) proved efficient. They make it possible to perform high-risk PCIs, including in clinics having neither appropriate equipment nor experience in ECMO.
[Mh] Termos MeSH primário: Ponte de Artéria Coronária/métodos
Doença da Artéria Coronariana
Oxigenação por Membrana Extracorpórea
Intervenção Coronária Percutânea/métodos
Fibrilação Ventricular
[Mh] Termos MeSH secundário: Idoso
Comorbidade
Ponte de Artéria Coronária/estatística & dados numéricos
Doença da Artéria Coronariana/diagnóstico
Doença da Artéria Coronariana/epidemiologia
Doença da Artéria Coronariana/mortalidade
Doença da Artéria Coronariana/cirurgia
Oxigenação por Membrana Extracorpórea/efeitos adversos
Oxigenação por Membrana Extracorpórea/instrumentação
Oxigenação por Membrana Extracorpórea/métodos
Feminino
Seres Humanos
Masculino
Meia-Idade
Avaliação de Processos e Resultados (Cuidados de Saúde)
Oxigenadores
Intervenção Coronária Percutânea/estatística & dados numéricos
Risco Ajustado/métodos
Fatores de Risco
Federação Russa/epidemiologia
Índice de Gravidade de Doença
Análise de Sobrevida
Fibrilação Ventricular/etiologia
Fibrilação Ventricular/terapia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1612
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160915
[St] Status:MEDLINE


  10 / 907 MEDLINE  
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[PMID]:27134304
[Au] Autor:Reagor JA; Holt DW
[Ad] Endereço:Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; and University of Nebraska Medical Center, Omaha, Nebraska.
[Ti] Título:Removal of Gross Air Embolization from Cardiopulmonary Bypass Circuits with Integrated Arterial Line Filters: A Comparison of Circuit Designs.
[So] Source:J Extra Corpor Technol;48(1):19-22, 2016 Mar.
[Is] ISSN:0022-1058
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Advances in technology, the desire to minimize blood product transfusions, and concerns relating to inflammatory mediators have lead many practitioners and manufacturers to minimize cardiopulmonary bypass (CBP) circuit designs. The oxygenator and arterial line filter (ALF) have been integrated into one device as a method of attaining a reduction in prime volume and surface area. The instructions for use of a currently available oxygenator with integrated ALF recommends incorporating a recirculation line distal to the oxygenator. However, according to an unscientific survey, 70% of respondents utilize CPB circuits incorporating integrated ALFs without a path of recirculation distal to the oxygenator outlet. Considering this circuit design, the ability to quickly remove a gross air bolus in the blood path distal to the oxygenator may be compromised. This in vitro study was designed to determine if the time required to remove a gross air bolus from a CPB circuit without a path of recirculation distal to the oxygenator will be significantly longer than that of a circuit with a path of recirculation distal to the oxygenator. A significant difference was found in the mean time required to remove a gross air bolus between the circuit designs (p = .0003). Additionally, There was found to be a statistically significant difference in the mean time required to remove a gross air bolus between Trial 1 and Trials 4 (p = .015) and 5 (p =.014) irrespective of the circuit design. Under the parameters of this study, a recirculation line distal to an oxygenator with an integrated ALF significantly decreases the time it takes to remove an air bolus from the CPB circuit and may be safer for clinical use than the same circuit without a recirculation line.
[Mh] Termos MeSH primário: Ponte Cardiopulmonar/efeitos adversos
Ponte Cardiopulmonar/instrumentação
Embolia Aérea/etiologia
Embolia Aérea/prevenção & controle
Filtração/instrumentação
Máquina Coração-Pulmão/efeitos adversos
Dispositivos de Acesso Vascular
[Mh] Termos MeSH secundário: Ponte Cardiopulmonar/métodos
Desenho de Equipamento
Seres Humanos
Oxigenadores/efeitos adversos
Dispositivos de Acesso Vascular/efeitos adversos
[Pt] Tipo de publicação:COMPARATIVE STUDY; EVALUATION STUDIES; JOURNAL ARTICLE
[Em] Mês de entrada:1607
[Cu] Atualização por classe:160701
[Lr] Data última revisão:
160701
[Sb] Subgrupo de revista:T
[Da] Data de entrada para processamento:160503
[St] Status:MEDLINE



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