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Pesquisa : E07.695.225 [Categoria DeCS]
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[PMID]:28863141
[Au] Autor:Kimura S; Morizane Y; Shiode Y; Hirano M; Doi S; Toshima S; Fujiwara A; Shiraga F
[Ad] Endereço:Department of Ophthalmology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
[Ti] Título:Assessment of tilt and decentration of crystalline lens and intraocular lens relative to the corneal topographic axis using anterior segment optical coherence tomography.
[So] Source:PLoS One;12(9):e0184066, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PURPOSE: To investigate the tilt and decentration of the crystalline lens and the intraocular lens (IOL) relative to the corneal topographic axis using anterior segment ocular coherence tomography (AS-OCT). METHODS: A sample set of 100 eyes from 49 subjects (41 eyes with crystalline lenses and 59 eyes with IOLs) were imaged using second generation AS-OCT (CASIA2, TOMEY) in June and July 2016 at Okayama University. Both mydriatic and non-mydriatic images were obtained, and the tilt and decentration of the crystalline lens and the IOL were quantified. The effects of pupil dilation on measurements were also assessed. RESULTS: The crystalline lens showed an average tilt of 5.15° towards the inferotemporal direction relative to the corneal topographic axis under non-mydriatic conditions and 5.25° under mydriatic conditions. Additionally, an average decentration of 0.11 mm towards the temporal direction was observed under non-mydriatic conditions and 0.08 mm under mydriatic conditions. The average tilt for the IOL was 4.31° towards the inferotemporal direction relative to the corneal topographic axis under non-mydriatic conditions and 4.65° in the same direction under mydriatic conditions. The average decentration was 0.05 mm towards the temporal direction under non-mydriatic conditions and 0.08 mm in the same direction under mydriatic conditions. A strong correlation was found between the average tilt and decentration values of the crystalline lens and the IOL under both non-mydriatic and mydriatic conditions (all Spearman correlation coefficients, r ≥ 0.800; all P < 0.001). CONCLUSION: When measured using second generation AS-OCT, both the crystalline lens and the IOL showed an average tilt of 4-6° toward the inferotemporal direction relative to the corneal topographic axis and an average decentration of less than 0.12 mm towards the temporal direction. These results were not influenced by pupil dilation and they showed good repeatability.
[Mh] Termos MeSH primário: Cristalino/fisiologia
Lentes Intraoculares
Tomografia de Coerência Óptica
[Mh] Termos MeSH secundário: Adulto
Idoso
Idoso de 80 Anos ou mais
Extração de Catarata/métodos
Córnea
Topografia da Córnea
Olho Artificial
Feminino
Seres Humanos
Implante de Lente Intraocular
Masculino
Registros Médicos
Meia-Idade
Midriáticos
Variações Dependentes do Observador
Facoemulsificação
Pupila/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Mydriatics)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171024
[Lr] Data última revisão:
171024
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170902
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0184066


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[PMID]:28267399
[Au] Autor:Bhattacharjee K; Bhattacharjee H; Kuri G; Singh M; Barman MJ
[Ad] Endereço:a Department of Orbit and Ophthalmic Plastic and Reconstructive Surgery, Sri Sankaradeva Nethralaya, Beltola , Guwahati , Assam , India.
[Ti] Título:Single-stage socket reconstruction with vascularised temporalis muscle flap following total orbital exenteration: Description of 3 surgical approaches.
[So] Source:Orbit;36(2):69-77, 2017 Apr.
[Is] ISSN:1744-5108
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:We describe the techniques and outcome of three different approaches to transfer the posterior 2/3 temporalis muscle pedicle flap for orbital socket reconstruction following total orbital exenteration. A retrospective interventional series of 9 patients operated between February of 2000 and 2006. We describe three different techniques, namely supraorbital, transorbital and transorbitectomy approach. All patients were followed for minimum of 3 years and muscle trophism with periorbital contour was clinically studied for outcome. There were 6 males and 3 females with a mean age of 42 years. Three patients each underwent the three mentioned approaches of socket reconstruction following total orbital exenteration performed mainly for oculo-adenexal malignancies with orbital extension (77.78%). Intraoperative, tumor-free histopathological margins were ensured. Postoperatively, bulky lateral orbital rim was noticed in all 3 patients of supraorbital approach, while progressive temporalis flap atrophy was noticed in all with transorbital approach over a period of 6 months. No such complications were observed in transorbitectomy approach and reasonably good periorbital cosmetic appearance with optimum preservation of muscle trophism was obtained. The mean follow-up period was 7 years. Temporalis muscle flap provides adequate orbital volume restoration in an exenterated socket. It also helps in better skin graft uptake, socket health and appearance. The transorbitectomy approach appeared as a reliable one stage surgical technique with reasonably acceptable anatomical and cosmetic outcome over a long-term follow-up. The choice of posterior portion of temporalis muscle as a flap offers satisfactory temporal fossa appearance.
[Mh] Termos MeSH primário: Exenteração Orbitária
Órbita/cirurgia
Procedimentos Cirúrgicos Reconstrutivos/métodos
Retalhos Cirúrgicos
Músculo Temporal/cirurgia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Criança
Estética
Olho Artificial
Feminino
Seguimentos
Seres Humanos
Masculino
Meia-Idade
Implantes Orbitários
Implante de Prótese
Estudos Retrospectivos
Músculo Temporal/irrigação sanguínea
Transferência Tendinosa
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171006
[Lr] Data última revisão:
171006
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170308
[St] Status:MEDLINE
[do] DOI:10.1080/01676830.2017.1279655


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[PMID]:28146369
[Au] Autor:Merritt H; Pfeiffer ML; Phillips ME; Richani K
[Ad] Endereço:a Ruiz Department of Ophthalmology and Visual Science , The University of Texas Health Science Center at Houston , Houston , Texas , USA.
[Ti] Título:Evisceration in patients with Sturge-Weber syndrome.
[So] Source:Orbit;36(1):48-51, 2017 Feb.
[Is] ISSN:1744-5108
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The management of blind, painful eyes in Sturge-Weber syndrome patients poses unique challenges to the oculoplastic surgeon. Intraocular and orbital vascular malformations and calcification may theoretically lead to unexpected hemorrhage and difficulty placing an implant in a calcified scleral shell. We present two cases of patients with Sturge-Weber syndrome with blind, painful eyes who underwent evisceration with silicone implant and discuss the relevant current literature. Both of our patients had uncomplicated surgeries and post-operative courses. Our literature review reveals that both evisceration and enucleation are viable surgical options for globe removal in Sturge-Weber syndrome, yet careful preoperative planning must be undertaken to minimize risk.
[Mh] Termos MeSH primário: Evisceração do Olho
Síndrome de Sturge-Weber/cirurgia
[Mh] Termos MeSH secundário: Cegueira/cirurgia
Dor Ocular/cirurgia
Olho Artificial
Seres Humanos
Masculino
Meia-Idade
Implantes Orbitários
Implante de Prótese
Síndrome de Sturge-Weber/diagnóstico
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170911
[Lr] Data última revisão:
170911
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170202
[St] Status:MEDLINE
[do] DOI:10.1080/01676830.2017.1279643


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[PMID]:28116022
[Au] Autor:Sayegh JS; Lahham S; Woodhouse L; Seong J; McCoy CE
[Ad] Endereço:University of California, Irvine, School of Medicine, Irvine, California; University of California, Irvine, UC Irvine Medical Center, Orange, California.
[Ti] Título:Creation of a Realistic Model for Removal of a Metallic Corneal Foreign Body for Less than $75.
[So] Source:West J Emerg Med;18(1):121-125, 2017 Jan.
[Is] ISSN:1936-9018
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Medicina de Emergência/educação
Corpos Estranhos no Olho/cirurgia
Internato e Residência
Modelos Anatômicos
Estudantes de Medicina
Materiais de Ensino/economia
[Mh] Termos MeSH secundário: Córnea/cirurgia
Medicina de Emergência/economia
Olho Artificial
Cabeça
Seres Humanos
Estados Unidos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170525
[Lr] Data última revisão:
170525
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170125
[St] Status:MEDLINE
[do] DOI:10.5811/westjem.2016.10.32234


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[PMID]:28057637
[Au] Autor:White C
[Ad] Endereço:London.
[Ti] Título:João Lobo Antunes.
[So] Source:BMJ;356:j45, 2017 Jan 05.
[Is] ISSN:1756-1833
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Olho Artificial/história
Neurocirurgia/história
[Mh] Termos MeSH secundário: Escolha da Profissão
História do Século XX
História do Século XXI
[Pt] Tipo de publicação:BIOGRAPHY; HISTORICAL ARTICLE; JOURNAL ARTICLE; PORTRAITS
[Ps] Nome de pessoa como assunto:Antunes JL
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170107
[St] Status:MEDLINE
[do] DOI:10.1136/bmj.j45


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[PMID]:27966517
[Au] Autor:Bankoti P; Singhal MK; Nair C; Chandra P
[Ad] Endereço:Department of Prosthodontics, Institute of Dental Sciences, Bareilly, Uttar Pradesh, India.
[Ti] Título:Characterization of an eye prosthesis using monopoly syrup.
[So] Source:Indian J Dent Res;27(5):553-558, 2016 Sep-Oct.
[Is] ISSN:1998-3603
[Cp] País de publicação:India
[La] Idioma:eng
[Ab] Resumo:The eye is a vital organ and an important component of facial expression. Loss of an eye has a crippling effect on the psychology of the patient. Maxillofacial prostheses restore and replace stomatognathic and associated facial structures with artificial substitutes. The objectives of eye prosthesis is to improve the patient esthetics, restore and maintain the health of the remaining associated structures, consequently provide physical and mental well-being. The primary purpose of an ocular prosthesis is to maintain the volume of eye socket and create the illusion of a healthy eye and surrounding tissue. A custom ocular prosthesis is a good option when reconstruction is done by plastic surgery, and osseointegrated implants are either not possible or not desired. A case of a custom-made ocular acrylic prosthesis is presented with acceptable fit, good retention, and esthetics.
[Mh] Termos MeSH primário: Olho Artificial
[Mh] Termos MeSH secundário: Enucleação Ocular
Seres Humanos
Masculino
Meia-Idade
Desenho de Prótese/métodos
Ceras/uso terapêutico
[Pt] Tipo de publicação:CASE REPORTS
[Nm] Nome de substância:
0 (Waxes)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171012
[Lr] Data última revisão:
171012
[Sb] Subgrupo de revista:D
[Da] Data de entrada para processamento:161215
[St] Status:MEDLINE
[do] DOI:10.4103/0970-9290.195684


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[PMID]:27741256
[Au] Autor:Tan DW; Lim SG; Wong TT; Venkatraman SS
[Ad] Endereço:School of Materials Science and Engineering, Nanyang Technological University, Singapore, Singapore.
[Ti] Título:Sustained Antibiotic-Eluting Intra-Ocular Lenses: A New Approach.
[So] Source:PLoS One;11(10):e0163857, 2016.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Currently, infections following cataract surgery are not as effectively managed with antibiotic eye drops, which suffer from poor bioavailability of drug and low patient compliance. The ideal solution, which can help to overcome the issue of drug wastage and poor bioavailabilty, as well as the need for frequent applications (patient inconvenience), is a drug-eluting intraocular lens (IOL). We describe a novel approach to such a drug-eluting lens by using a peripheral IOL attachment as a drug depot to deliver antibiotics, Levofloxacin (LFX) or Moxifloxacin (MFX). In this work, drug was entrapped within a fully-degradable polymer, poly(L-lactide-co-É›-caprolactone) (PLC). The effects of drug loading and solvent type on drug release and film morphology were investigated using cast films. The study clearly demonstrated that a slower-evaporating solvent tetrahydrofuran (THF) resulted in a better surface morphology, as well as lower initial burst compared to dichloromethane (DCM), and hence, was better suited to developing a drug-eluting attachment with sustained release of drug. When attachments were fabricated with drugs at high loading percentages (20% and 25% in polymer), significant burst was observed compared to films: this is attributed to the higher surface-to-volume ratio of the attachments. When the levofloxacin (LFX) loading percentage was decreased to 3% and 5%, the attachments presented lower burst and sustained release with therapeutic efficacy. This work has demonstrated the potential of using an IOL attachment as a more efficacious anti-infective option compared to daily eye drops.
[Mh] Termos MeSH primário: Antibacterianos/metabolismo
Portadores de Fármacos/química
Lentes Intraoculares
[Mh] Termos MeSH secundário: Antibacterianos/química
Liberação Controlada de Fármacos
Olho Artificial
Fluoroquinolonas/química
Fluoroquinolonas/metabolismo
Furanos/química
Interações Hidrofóbicas e Hidrofílicas
Levofloxacino/química
Levofloxacino/metabolismo
Cloreto de Metileno/química
Microscopia Eletrônica de Varredura
Poliésteres/química
Propriedades de Superfície
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); 0 (Drug Carriers); 0 (Fluoroquinolones); 0 (Furans); 0 (Polyesters); 3N8FZZ6PY4 (tetrahydrofuran); 588X2YUY0A (Methylene Chloride); 6GNT3Y5LMF (Levofloxacin); 70524-20-8 (lactide-caprolactone copolymer); U188XYD42P (moxifloxacin)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170613
[Lr] Data última revisão:
170613
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161015
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0163857


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[PMID]:27612795
[Au] Autor:Santos DM; Nagay BE; da Silva EV; Bonatto Lda R; Sonego MV; Moreno A; Rangel EC; da Cruz NC; Goiato MC
[Ad] Endereço:Department of Dental Materials and Prosthodontics, Aracatuba Dental School, Sao Paulo State University (UNESP), Aracatuba, Sao Paulo, Brazil. Electronic address: danielamicheline@foa.unesp.br.
[Ti] Título:In vitro analysis of different properties of acrylic resins for ocular prosthesis submitted to accelerated aging with or without photopolymerized glaze.
[So] Source:Mater Sci Eng C Mater Biol Appl;69:995-1003, 2016 Dec 01.
[Is] ISSN:1873-0191
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:The effect of a photopolymerized glaze on different properties of acrylic resin (AR) for ocular prostheses submitted to accelerated aging was investigated. Forty discs were divided into 4 groups: N1 AR without glaze (G1); colorless AR without glaze (G2); N1 AR with glaze (G3); and colorless AR with glaze (G4). All samples were polished with sandpaper (240, 600 and 800-grit). In G1 and G2, a 1200-grit sandpaper was also used. In G3 and G4, samples were coated with MegaSeal glaze. Property analysis of color stability, microhardness, roughness, and surface energy, and assays of atomic force microscopy, scanning electron microscopy, and energy-dispersive spectroscopy were performed before and after the accelerated aging (1008h). Data were submitted to the ANOVA and Tukey Test (p<0.05). Groups with glaze exhibited statistically higher color change and roughness after aging. The surface microhardness significantly decreased in groups with glaze and increased in groups without glaze. The surface energy increased after the aging, independent of the polishing procedure. All groups showed an increase of surface irregularities. Photopolymerized glaze is an inadequate surface treatment for AR for ocular prostheses and it affected the color stability, roughness, and microhardness. The accelerated aging interfered negatively with the properties of resins.
[Mh] Termos MeSH primário: Resinas Acrílicas/química
Olho Artificial
Luz
Polimerização
[Mh] Termos MeSH secundário: Dureza
Microscopia de Força Atômica
Microscopia Eletrônica de Varredura
Espectrometria por Raios X
Fatores de Tempo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Acrylic Resins)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170421
[Lr] Data última revisão:
170421
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160911
[St] Status:MEDLINE


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[PMID]:27525534
[Au] Autor:Dave TV; Kumar S; Vasanthalin J; Kaliki S; Ali MJ; Naik MN
[Ad] Endereço:*MD †BSc Socket, Anophthalmia and Orbitofacial Prosthesis Services (TVD, SK, JV), and Ophthalmic Plastic Surgery Services (TVD, SK, MJA, MNN), L. V. Prasad Eye Institute, Kallam Anji Reddy Campus, Banjara Hills, Hyderabad, India.
[Ti] Título:Development and Validation of a Grading Scale for Custom Ocular Prosthesis.
[So] Source:Optom Vis Sci;93(11):1426-1430, 2016 Nov.
[Is] ISSN:1538-9235
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PURPOSE: To develop a standardized and universally reproducible grading scale for artistic outcome of a custom ocular prosthesis. METHODS: A retrospective review of photographs of patients with custom ocular prosthesis. From the ocularistry database of a tertiary eye care hospital, photographs of patients with custom ocular prosthesis (30 random photos with additional 18 repetitions, total n = 50) were selected. Two independent oculoplastic surgeons, on the basis of characteristics of limbus, vascularity, and pigmentation, graded these photos. The photos were adjusted for confounders like magnification and illumination, and both graders used the same display system. The surgeons were blinded to each other. The characteristics were graded on a scale of 0 to 2 and total score was calculated for each photo. Inter-observer and intra-observer agreement was calculated using the kappa statistic. RESULTS: The inter-observer kappa coefficient for the three characteristics (95% confidence interval) were as follows: limbus 0.7 (0.55-0.85), vascularity 0.76 (0.58-0.94), and pigmentation 0.6 (0.34-0.85). The intra-observer kappa coefficient for the first surgeon was as follows: limbus 0.88 (0.7-0.95), vascularity 0.88 (0.73-0.95), and pigmentation 0.82 (0.54-0.93). The intra-observer kappa coefficient for the second surgeon was as follows: limbus 0.8 (0.44-0.93), vascularity 0.55 (0.13-0.8), and pigmentation 0.76 (0.6-0.84). CONCLUSIONS: A good intra- and inter-observer agreement was demonstrated. In view of no existing grading for prosthesis, this is a unique system to objectively grade the outcome of custom ocular prosthesis and can be incorporated in ocularistry teaching modules for standardization of outcomes.
[Mh] Termos MeSH primário: Olho Artificial/classificação
Olho Artificial/normas
[Mh] Termos MeSH secundário: Oftalmopatias/cirurgia
Enucleação Ocular
Evisceração do Olho
Seres Humanos
Variações Dependentes do Observador
Implantes Orbitários
Fotografia
Ajuste de Prótese
Reprodutibilidade dos Testes
Estudos Retrospectivos
[Pt] Tipo de publicação:JOURNAL ARTICLE; VALIDATION STUDIES
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170825
[Lr] Data última revisão:
170825
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160816
[St] Status:MEDLINE


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[PMID]:27521695
[Au] Autor:da Silva EVF; Goiato MC; Bonatto LDR; de Medeiros RA; Santos DMD; Rangel EC; Oliveira SHP
[Ad] Endereço:Department of Dental Materials and Prosthodontics, Aracatuba Dental School, Sao Paulo State University (UNESP), Jose Bonifacio St., 1153, Vila Mendonca, Aracatuba, Sao Paulo, Brazil.
[Ti] Título:Toxicity analysis of ocular prosthesis acrylic resin with or without pigment incorporation in human conjunctival cell line.
[So] Source:Toxicol In Vitro;36:180-185, 2016 Oct.
[Is] ISSN:1879-3177
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The aim of this study was to evaluate the influence of pigment incorporation on the cytotoxicity of ocular prosthesis N1 color acrylic resin. Nine samples were manufactured by heat-polymerization in water bath and divided into 3 groups: acrylic resin without pigment incorporation (group R), acrylic resin with pigment incorporation (group RP), and acrylic pigment (group P). Eluates formed after 72h of sample immersion in medium were incubated with conjunctival cell line (Chang conjunctival cells) for 72h. The negative control group consisted in medium without samples (group C). The cytotoxic effect from the eluates was evaluated using MTT assay (cell proliferation), ELISA assay (quantification of IL1ß, IL6, TNF α and CCL3/MIP1α) and RT-PCR assay (mRNA expression of COL IV, TGF ß and MMP9). Data were submitted to ANOVA with Bonferroni post-tests (p<0.05). All groups were considered non-cytotoxic based on cell proliferation. However, resin with pigment incorporation showed significant IL6 quantity increase. Resin without pigment incorporation exhibited higher mRNA expression of COL IV, MMP9 and TGF ß, however it was also observed for the negative control group. The materials exhibited divergent biological behavior. Despite the pigment incorporation that resulted in an increase of IL6, no cytotoxicity was observed based on cell proliferation.
[Mh] Termos MeSH primário: Resinas Acrílicas/toxicidade
Corantes/toxicidade
Túnica Conjuntiva/citologia
Olho Artificial
[Mh] Termos MeSH secundário: Linhagem Celular
Proliferação Celular/efeitos dos fármacos
Colágeno Tipo IV/genética
Seres Humanos
Metaloproteinase 9 da Matriz/genética
RNA Mensageiro/metabolismo
Fator de Crescimento Transformador beta/genética
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Acrylic Resins); 0 (Collagen Type IV); 0 (Coloring Agents); 0 (RNA, Messenger); 0 (Transforming Growth Factor beta); EC 3.4.24.35 (MMP9 protein, human); EC 3.4.24.35 (Matrix Metalloproteinase 9)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170529
[Lr] Data última revisão:
170529
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160814
[St] Status:MEDLINE



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