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[PMID]:29304035
[Au] Autor:Frost K; Bertocci G; Smalley C
[Ad] Endereço:Department of Bioengineering, J.B. Speed School of Engineering, University of Louisville, Louisville, Kentucky, United States of America.
[Ti] Título:Wheelchair tiedown and occupant restraint practices in paratransit vehicles.
[So] Source:PLoS One;13(1):e0186829, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The purpose of this study was to characterize wheelchair tiedown and occupant restraint system (WTORS) usage in paratransit vehicles based on observations of wheelchair and scooter (wheeled mobility devices, collectively, "WhMD") passenger trips. A retrospective review of on-board video monitoring recordings of WhMD trips was conducted. Four hundred seventy-five video recordings were collected for review and analysis. The use of all four tiedowns to secure the WhMD was observed more frequently for power WhMDs (82%) and manual WhMDs (80%) compared to scooters (39%), and this difference was significant (p< 0.01). Nonuse or misuse of the occupant restraint system occurred during 88% of WhMD trips, and was most frequently due to vehicle operator neglect in applying the shoulder belt. Despite the absence of incidents or injuries in this study, misuse and nonuse of WTORS potentially place WhMD seated passengers at higher risk of injury during transit. These findings support the need for improved vehicle operator training and passenger education on the proper use of WTORS and development of WTORS with improved usability and/or alternative technologies that can be automated or used independently.
[Mh] Termos MeSH primário: Veículos Automotores
Equipamentos de Proteção/utilização
Cintos de Segurança
Cadeiras de Rodas
[Mh] Termos MeSH secundário: Acidentes de Trânsito/prevenção & controle
Pessoas com Deficiência
Seres Humanos
Kentucky
Estudos Retrospectivos
Segurança
Cintos de Segurança/utilização
Equipamentos de Autoajuda/utilização
Gravação em Vídeo
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180210
[Lr] Data última revisão:
180210
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180106
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0186829


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[PMID]:28468679
[Au] Autor:Korall AMB; Godin J; Feldman F; Cameron ID; Leung PM; Sims-Gould J; Robinovitch SN
[Ad] Endereço:Injury Prevention and Mobility Laboratory (IPML), Simon Fraser University, 8888 University Drive, Burnaby, BC, V5A 1S6, Canada. akorall@sfu.ca.
[Ti] Título:Validation and psychometric properties of the commitment to hip protectors (C-HiP) index in long-term care providers of British Columbia, Canada: a cross-sectional survey.
[So] Source:BMC Geriatr;17(1):103, 2017 05 03.
[Is] ISSN:1471-2318
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: If worn during a fall, hip protectors substantially reduce risk for hip fracture. However, a major barrier to their clinical efficacy is poor user adherence. In long-term care, adherence likely depends on how committed care providers are to hip protectors, but empirical evidence is lacking due to the absence of a psychometrically valid assessment tool. METHODS: We conducted a cross-sectional survey in a convenience sample of 529 paid care providers. We developed the 15-item C-HiP Index to measure commitment, comprised of three subscales: affective, cognitive and behavioural. Responses were subjected to hierarchical factor analysis and internal consistency testing. Eleven experts rated the relevance and clarity of items on 4-point Likert scales. We performed simple linear regression to determine whether C-HiP Index scores were positively related to the question, "Do you think of yourself as a champion of hip protectors", rated on a 5-point Likert scale. We examined whether the C-HiP Index could differentiate respondents: (i) who were aware of a protected fall causing hip fracture from those who were unaware; (ii) who agreed in the existence of a champion of hip protectors within their home from those who didn't. RESULTS: Hierarchical factor analysis yielded two lower-order factors and a single higher-order factor, representing the overarching concept of commitment to hip protectors. Items from affective and cognitive subscales loaded highest on the first lower-order factor, while items from the behavioural subscale loaded highest on the second. We eliminated one item due to low factor matrix coefficients, and poor expert evaluation. The C-HiP Index had a Cronbach's alpha of 0.96. A one-unit increase in championing was associated with a 5.2-point (p < 0.01) increase in C-HiP Index score. Median C-HiP Index scores were 4.3-points lower (p < 0.01) among respondents aware of a protected fall causing hip fracture, and 7.0-points higher (p < 0.01) among respondents who agreed in the existence of a champion of hip protectors within their home. CONCLUSIONS: We offer evidence of the psychometric properties of the C-HiP Index. The development of a valid and reliable assessment tool is crucial to understanding the factors that govern adherence to hip protectors in long-term care.
[Mh] Termos MeSH primário: Cuidadores/psicologia
Cuidadores/normas
Assistência de Longa Duração/normas
Aparelhos Ortopédicos/normas
Equipamentos de Proteção/normas
[Mh] Termos MeSH secundário: Acidentes por Quedas/prevenção & controle
Adulto
Idoso
Colúmbia Britânica/epidemiologia
Estudos Transversais
Feminino
Fraturas do Quadril/epidemiologia
Fraturas do Quadril/prevenção & controle
Fraturas do Quadril/psicologia
Seres Humanos
Assistência de Longa Duração/tendências
Meia-Idade
Aparelhos Ortopédicos/tendências
Equipamentos de Proteção/tendências
Psicometria
[Pt] Tipo de publicação:JOURNAL ARTICLE; VALIDATION STUDIES; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1712
[Cu] Atualização por classe:180127
[Lr] Data última revisão:
180127
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170505
[St] Status:MEDLINE
[do] DOI:10.1186/s12877-017-0493-5


  3 / 6412 MEDLINE  
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[PMID]:29240789
[Au] Autor:Zhang W; Cao J; Xu J
[Ad] Endereço:Department of Automotive Engineering, School of Transportation Science and Engineering, Beihang University, Beijing, China.
[Ti] Título:How to quantitatively evaluate safety of driver behavior upon accident? A biomechanical methodology.
[So] Source:PLoS One;12(12):e0189455, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:How to evaluate driver spontaneous reactions in various collision patterns in a quantitative way is one of the most important topics in vehicle safety. Firstly, this paper constructs representative numerical crash scenarios described by impact velocity, impact angle and contact position based on finite element (FE) computation platform. Secondly, a driver cabin model is extracted and described in the well validated multi-rigid body (MB) model to compute the value of weighted injury criterion to quantitatively assess drivers' overall injury under certain circumstances. Furthermore, based on the coupling of FE and MB, parametric studies on various crash scenarios are conducted. It is revealed that the WIC (Weighted Injury Criteria) value variation law under high impact velocities is quite distinct comparing with the one in low impact velocities. In addition, the coupling effect can be elucidated by the fact that the difference of WIC value among three impact velocities under smaller impact angles tends to be distinctly higher than that under larger impact angles. Meanwhile, high impact velocity also increases the sensitivity of WIC under different collision positions and impact angles. Results may provide a new methodology to quantitatively evaluate driving behaviors and serve as a significant guiding step towards collision avoidance for autonomous driving vehicles.
[Mh] Termos MeSH primário: Acidentes de Trânsito
Condução de Veículo
Fenômenos Biomecânicos
Segurança
[Mh] Termos MeSH secundário: Seres Humanos
Equipamentos de Proteção
Ferimentos e Lesões
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180116
[Lr] Data última revisão:
180116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171215
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0189455


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[PMID]:29190036
[Au] Autor:Reddy VK; Lavoie MC; Verbeek JH; Pahwa M
[Ad] Endereço:Cochrane Work Review Group, Finnish Institute of Occupational Health, Neulaniementie 4, Kuopio, Finland, 70101.
[Ti] Título:Devices for preventing percutaneous exposure injuries caused by needles in healthcare personnel.
[So] Source:Cochrane Database Syst Rev;11:CD009740, 2017 11 14.
[Is] ISSN:1469-493X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Percutaneous exposure injuries from devices used for blood collection or for injections expose healthcare workers to the risk of blood borne infections such as hepatitis B and C, and human immunodeficiency virus (HIV). Safety features such as shields or retractable needles can possibly contribute to the prevention of these injuries and it is important to evaluate their effectiveness. OBJECTIVES: To determine the benefits and harms of safety medical devices aiming to prevent percutaneous exposure injuries caused by needles in healthcare personnel versus no intervention or alternative interventions. SEARCH METHODS: We searched CENTRAL, MEDLINE, EMBASE, NHSEED, Science Citation Index Expanded, CINAHL, Nioshtic, CISdoc and PsycINFO (until 11 November 2016). SELECTION CRITERIA: We included randomised controlled trials (RCT), controlled before and after studies (CBA) and interrupted time-series (ITS) designs of the effect of safety engineered medical devices on percutaneous exposure injuries in healthcare staff. DATA COLLECTION AND ANALYSIS: Two of the authors independently assessed study eligibility and risk of bias and extracted data. We synthesized study results with a fixed-effect or random-effects model meta-analysis where appropriate. MAIN RESULTS: We included six RCTs with 1838 participants, two cluster-RCTs with 795 participants and 73,454 patient days, five CBAs with approximately 22,000 participants and eleven ITS with an average of 13.8 data points. These studies evaluated safe modifications of blood collection systems, intravenous (IV) systems, injection systems, multiple devices, sharps containers and legislation on the implementation of safe devices. We estimated the needlestick injury (NSI) rate in the control groups to be about one to five NSIs per 1000 person-years. There were only two studies from low- or middle-income countries. The risk of bias was high in 20 of 24 studies. Safe blood collection systems:We found one RCT that found a safety engineered blood gas syringe having no considerable effect on NSIs (Relative Risk (RR) 0.2, 95% Confidence Interval (95% CI) 0.01 to 4.14, 550 patients, very low quality evidence). In one ITS study, safe blood collection systems decreased NSIs immediately after the introduction (effect size (ES) -6.9, 95% CI -9.5 to -4.2) but there was no further decrease over time (ES -1.2, 95% CI -2.5 to 0.1, very low quality evidence). Another ITS study evaluated an outdated recapping shield, which we did not consider further. Safe Intravenous systemsThere was very low quality evidence in two ITS studies that NSIs were reduced with the introduction of safe IV devices, whereas one RCT and one CBA study provided very low quality evidence of no effect. However, there was moderate quality evidence produced by four other RCT studies that these devices increased the number of blood splashes when the safety system had to be engaged actively (relative risk (RR) 1.6, 95% CI 1.08 to 2.36). In contrast there was low quality evidence produced by two RCTs of passive systems that showed no effect on blood splashes. Yet another RCT produced low quality evidence that a different safe active IV system also decreased the incidence of blood leakages. Safe injection devicesThere was very low quality evidence provided by one RCT and one CBA study showing that introduction of safe injection devices did not considerably change the NSI rate. One ITS study produced low quality evidence showing that the introduction of safe passive injection systems had no effect on NSI rate when compared to safe active injection systems. Multiple safe devicesThere was very low quality evidence from one CBA study and two ITS studies. According to the CBA study, the introduction of multiple safe devices resulted in a decrease in NSI,whereas the two ITS studies found no change. Safety containersOne CBA study produced very low quality evidence showing that the introduction of safety containers decreased NSI. However, two ITS studies evaluating the same intervention found inconsistent results. LegislationThere was low to moderate quality evidence in two ITS studies that introduction of legislation on the use of safety-engineered devices reduced the rate of NSIs among healthcare workers. There was also low quality evidence which showed a decrease in the trend over time for NSI rates.Twenty out of 24 studies had a high risk of bias and the lack of evidence of a beneficial effect could be due to both confounding and bias. This does not mean that these devices are not effective. AUTHORS' CONCLUSIONS: For safe blood collection systems, we found very low quality evidence of inconsistent effects on NSIs. For safe passive intravenous systems, we found very low quality evidence of a decrease in NSI and a reduction in the incidence of blood leakage events but moderate quality evidence that active systems may increase exposure to blood. For safe injection needles, the introduction of multiple safety devices or the introduction of sharps containers the evidence was inconsistent or there was no clear evidence of a benefit. There was low to moderate quality evidence that introduction of legislation probably reduces NSI rates.More high-quality cluster-randomised controlled studies that include cost-effectiveness measures are needed, especially in countries where both NSIs and blood-borne infections are highly prevalent.
[Mh] Termos MeSH primário: Coleta de Amostras Sanguíneas/instrumentação
Pessoal de Saúde
Ferimentos Penetrantes Produzidos por Agulha/prevenção & controle
Doenças Profissionais/prevenção & controle
Equipamentos de Proteção
[Mh] Termos MeSH secundário: Coleta de Amostras Sanguíneas/métodos
Estudos Controlados Antes e Depois
Seres Humanos
Infusões Intravenosas/instrumentação
Injeções/instrumentação
Ferimentos Penetrantes Produzidos por Agulha/epidemiologia
Doenças Profissionais/epidemiologia
Equipamento de Proteção Individual
Ensaios Clínicos Controlados Aleatórios como Assunto
[Pt] Tipo de publicação:JOURNAL ARTICLE; META-ANALYSIS; REVIEW
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180110
[Lr] Data última revisão:
180110
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171201
[St] Status:MEDLINE
[do] DOI:10.1002/14651858.CD009740.pub3


  5 / 6412 MEDLINE  
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[PMID]:29185685
[Au] Autor:Hildwine F
[Ti] Título:Take A Seat: New ambulance seating improves safety, size and functionality.
[So] Source:JEMS;41(10):38-42, 2016 10.
[Is] ISSN:0197-2510
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Acidentes de Trabalho/prevenção & controle
Ambulâncias
Desenho de Equipamento
Segurança de Equipamentos
Equipamentos de Proteção
Ferimentos e Lesões/prevenção & controle
[Mh] Termos MeSH secundário: Seres Humanos
Postura/fisiologia
Cintos de Segurança
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180108
[Lr] Data última revisão:
180108
[Sb] Subgrupo de revista:H
[Da] Data de entrada para processamento:171201
[St] Status:MEDLINE


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[PMID]:29019891
[Au] Autor:Schultz J; Leupold S; Grählert X; Pfeiffer R; Schwanebeck U; Schröttner P; Djawid B; Artsimovich W; Kozak K; Fitze G
[Ad] Endereço:aPediatric Surgery bCoordinating Centre for Clinical Trials Dresden cInstitute of Medical Microbiology and Hygiene, Carl Gustav Carus Medical Faculty, Technische Universität Dresden, Fetscherstrasse dFraunhofer Institute for Material and Beam Technology IWS Dresden eCarl Gustav Carus Medical Faculty, Technische Universität Dresden, Fetscherstrasse, Dresden, Germany fWroclaw Medical University, Wybrzeze Ludwika Pasteura 1, Wroclaw, Poland.
[Ti] Título:Study protocol for a randomized controlled pilot-trial on the semiocclusive treatment of fingertip amputation injuries using a novel finger cap.
[So] Source:Medicine (Baltimore);96(41):e8224, 2017 Oct.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: Fingertip amputation injuries are common in all ages. Conservatively treated fingertips can regenerate skin and soft tissues to form a functionally and cosmetically excellent new fingertip. Little is known about this ability that, in humans, is confined to the fingertips. Even less is known about the role of the bacteria that regularly colonize these wounds without negative impact on regeneration and healing.As an alternative to surgery, self-adhesive film dressings are commonly used to establish a wet chamber around the injury. These dressings leak malodorous wound fluid eventually until the wound is dry. Having that into consideration, we have therefore developed a silicone finger cap that forms a mechanically protected, wet chamber around the injury for optimal regeneration conditions. It contains a puncturable reservoir for excess wound fluid, which can be thus routinely analyzed for diagnostic and research purposes.This study protocol explains the first randomized controlled trial (RCT) on the semiocclusive treatment of fingertip amputations in both children and adults comparing traditional film dressings with the novel silicone finger cap. Being the first RCT using 2 medical devices not yet certified for this indication, it will gather valuable information for the understanding of fingertip regeneration and the design of future definitive studies. METHODS AND ANALYSIS: By employing an innovative pseudo-cross-over-design with a dichotomous primary endpoint based on patients preference, this pilot study will gain statistically significant data with a very limited sample size. Our RCT will investigate acceptance, safety, effectiveness, and efficacy of this novel medical device while gathering information on the clinical course and outcome of conservatively treated fingertip injuries. A total of 22 patients older than 2 years will be randomly assigned to start the conservative treatment with either the traditional film-dressing or the novel finger cap. The treatment will be changed to the other alternative for another 2 weeks before the patient or the guardian is confronted with the decision of which method they would prefer for the rest of the treatment (if required). ETHICS AND DISSEMINATION: Ethical approval (EK 148042015) of the study protocol has been obtained from Institutional Review Board at the TU Dresden. The trial is registered at the European Database on Medical Devices (EUDAMED-No.: CIV-15-03-013246) and at ClinicalTrials.gov (NCT03089060).
[Mh] Termos MeSH primário: Tratamento Conservador/métodos
Traumatismos dos Dedos/terapia
Equipamentos de Proteção
Lesões dos Tecidos Moles/terapia
[Mh] Termos MeSH secundário: Adulto
Amputação Traumática/complicações
Pesquisa Comparativa da Efetividade
Desenho de Equipamento
Feminino
Traumatismos dos Dedos/etiologia
Seres Humanos
Masculino
Curativos Oclusivos
Projetos Piloto
Reepitelização/efeitos dos fármacos
Projetos de Pesquisa
Silicones/uso terapêutico
Lesões dos Tecidos Moles/etiologia
Técnicas de Fechamento de Ferimentos
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Silicones)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171122
[Lr] Data última revisão:
171122
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171012
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000008224


  7 / 6412 MEDLINE  
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[PMID]:28790256
[Au] Autor:Hirai K
[Ad] Endereço:Faculty of Medicine, School of Nursing, Tokyo Medical University.
[Ti] Título:[Safe Handling of Hazardous Drugs in Nursing Practice].
[So] Source:Gan To Kagaku Ryoho;44(7):558-562, 2017 Jul.
[Is] ISSN:0385-0684
[Cp] País de publicação:Japan
[La] Idioma:jpn
[Ab] Resumo:Handling of hazardous drugs in nursing practice, there are risks of a wide variety of occupational exposures such as drug administration, management of spills, care of patients after administration, etc. Using a general infusion set for intravenous administration, there are risk of exposure such as scattering when the bottle needle is spiked into the infusion bag, leakage when priming the infusion line with antineoplastic drug, spillage when removing the side tube. For intravenous administration, use of CSTD for administration is most effective, but in many facilities, a general infusion set is used due to cost considerations. Drug preparation for local infusion is often done on the patients' bedside and is one of the most dangerous tasks for nurses who assist. There are also risks of exposure when handling patient excreta, body fluids and linen contaminated with them. Exposure measures are necessary for a minimum of 48 hours after administration. In the prevention of occupational exposure in these tasks, understanding and cooperation of doctors and pharmacists is particularly indispensable. Also, patients and families need to be provided appropriate guidance on exposure control. Under the organizational recognition and efforts against exposure control, it is necessary to create an environment in which all medical staff can devote themselves to work with confidence.
[Mh] Termos MeSH primário: Antineoplásicos/uso terapêutico
Exposição Ocupacional/prevenção & controle
Prática Profissional
Gestão da Segurança
[Mh] Termos MeSH secundário: Seres Humanos
Enfermeiras e Enfermeiros
Equipamentos de Proteção
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antineoplastic Agents)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170911
[Lr] Data última revisão:
170911
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170810
[St] Status:MEDLINE


  8 / 6412 MEDLINE  
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[PMID]:28790255
[Au] Autor:Nomura H
[Ad] Endereço:Dept. of Pharmacy, National Cancer Center Hospital East.
[Ti] Título:[Safe Handling of Cancer Chemotherapy Drugs in Pharmacy(Preparations, Transport and Safe Deposit)].
[So] Source:Gan To Kagaku Ryoho;44(7):554-557, 2017 Jul.
[Is] ISSN:0385-0684
[Cp] País de publicação:Japan
[La] Idioma:jpn
[Ab] Resumo:Recently, 1 out of 2 people are diagnosed as cancer, the number of patients who are given chemotherapy increases year by year. As a result, amount of anticancer drugs used also increases. Anticancer drug preparation work is one of pharmacist work. In many hospital, pharmacists prepare anticancer drugs at pharmacy. However, it is enough to take steps to exposure measures at all facilities. According to the United States Pharmacopeial(USP)and the handling standards of hazardous and drugs, there are 3 levels, the first level(safety cabinet), the second level(anticancer agent preparation room in pharmacy) and supplemental engineering control(CSTD). It is described that exposure control should be carried out with exposure control. Strict standards are stated for each. In Japan, efforts to cope with exposure gradually are spreading gradually after exposure GL is published. Proper preparation environment/equipment, personal protective equipment, procedures and supplementary equipment are required for adequate exposure control measures. Also, it is important for exposure control to focus not only on anticancer drug preparation work but also on transportation and storage. This time, we describe exposure preparation, transportation to storage from dispensing.
[Mh] Termos MeSH primário: Antineoplásicos/uso terapêutico
Neoplasias/tratamento farmacológico
Exposição Ocupacional/prevenção & controle
Gestão da Segurança
[Mh] Termos MeSH secundário: Seres Humanos
Farmácia
Equipamentos de Proteção
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antineoplastic Agents)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170911
[Lr] Data última revisão:
170911
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170810
[St] Status:MEDLINE


  9 / 6412 MEDLINE  
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[PMID]:28790254
[Au] Autor:Yasui H
[Ad] Endereço:Dept. of Medical Oncology, Kobe City Medical Center General Hospital.
[Ti] Título:[Health Impacts Due to Occupational Exposure of Hazardous Drugs(HD)].
[So] Source:Gan To Kagaku Ryoho;44(7):550-553, 2017 Jul.
[Is] ISSN:0385-0684
[Cp] País de publicação:Japan
[La] Idioma:jpn
[Ab] Resumo:Healthcare workers who occupationally handle hazardous drugs(HD)have been reported to be at high risk of reproductive toxicity and carcinogenicity by long-term exposure even in trace amounts. The risk is determined not only by the toxicity of the drug but also by how much HD is absorbed in the body. Adverse events due to exposure to anticancer drugs can be classified into biological effects expressed at the cell and gene level, and effects on health expressed on individual level, the latter appearing as acute symptoms in the short term. In the long term, the effects on reproduction and development of malignant tumors become a problem.
[Mh] Termos MeSH primário: Antineoplásicos/uso terapêutico
Exposição Ocupacional
[Mh] Termos MeSH secundário: Seres Humanos
Infertilidade/induzido quimicamente
Neoplasias/induzido quimicamente
Equipamentos de Proteção
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antineoplastic Agents)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170911
[Lr] Data última revisão:
170911
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170810
[St] Status:MEDLINE


  10 / 6412 MEDLINE  
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[PMID]:28790253
[Au] Autor:Kanda K
[Ad] Endereço:Graduate School of Health Sciences, Gunma University.
[Ti] Título:[The Necessity and the Current Status of Safe Handling of Anticancer Drugs].
[So] Source:Gan To Kagaku Ryoho;44(7):545-549, 2017 Jul.
[Is] ISSN:0385-0684
[Cp] País de publicação:Japan
[La] Idioma:jpn
[Ab] Resumo:Number of people who handle anticancer drugs in their profession is increasing. Anticancer drugs, which are hazardous drugs(HD), exert cytocidal effects on cancer cells, but many have also been shown to have mutagenicity, teratogenicity and carcinogenicity; therefore, safe handling of anticancer drugs is necessary. In July 2015, the first Japanese guidelines for exposure control measures, namely, the "Joint Guidelines for Safe Handling of Cancer Chemotherapy Drugs", were published jointly by 3 societies. Our guideline is the creation of the Japanese Society of Cancer Nursing(JSCN), Japanese Society of Medical Oncology(JSMO)and Japanese Society of Pharmaceutical Oncology(JASPO)and has a historical significance. This paper states the necessity of safe handling of anticancer drugs, Japan's recent movement of safe handling, the introduction of joint guidelines of safe handling of anticancer drugs, and new movement of safe handling of USP chapter 800 in the United States.
[Mh] Termos MeSH primário: Antineoplásicos/uso terapêutico
Exposição Ocupacional/prevenção & controle
Guias de Prática Clínica como Assunto
Gestão da Segurança
[Mh] Termos MeSH secundário: Seres Humanos
Equipamentos de Proteção
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antineoplastic Agents)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170911
[Lr] Data última revisão:
170911
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170810
[St] Status:MEDLINE



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