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[PMID]:29280695
[Au] Autor:Iqbal IZ; Jones GH; Dawe N; Mamais C; Smith ME; Williams RJ; Kuhn I; Carrie S
[Ad] Endereço:Department of Otolaryngology,Freeman Hospital,Newcastle upon Tyne,UK.
[Ti] Título:Intranasal packs and haemostatic agents for the management of adult epistaxis: systematic review.
[So] Source:J Laryngol Otol;131(12):1065-1092, 2017 Dec.
[Is] ISSN:1748-5460
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The mainstay of management of epistaxis refractory to first aid and cautery is intranasal packing. This review aimed to identify evidence surrounding nasal pack use. METHOD: A systematic review of the literature was performed using standardised methodology. RESULTS: Twenty-seven eligible articles were identified relating to non-dissolvable packs and nine to dissolvable packs. Nasal packing appears to be more effective when applied by trained professionals. For non-dissolvable packs, the re-bleed rates for Rapid Rhino and Merocel were similar, but were higher with bismuth iodoform paraffin paste packing. Rapid Rhino packs were the most tolerated non-dissolvable packs. Evidence indicates that 96 per cent of re-bleeding occurs within the first 4 hours after nasal pack removal. Limited evidence suggests that dissolvable packs are effective and well tolerated by patients. There was a lack of evidence relating to: the duration of pack use, the economic effects of pack choice and the appropriate care setting for non-dissolvable packs. CONCLUSION: Rapid Rhino packs are the best tolerated, with efficacy equivalent to nasal tampons. FloSeal is easy to use, causes less discomfort and may be superior to Merocel in anterior epistaxis cases. There is no strong evidence to support prophylactic antibiotic use.
[Mh] Termos MeSH primário: Epistaxe/terapia
Hemostáticos/uso terapêutico
Tampões Cirúrgicos
[Mh] Termos MeSH secundário: Adulto
Terapia Combinada
Eletrocoagulação
Primeiros Socorros
Seres Humanos
Resultado do Tratamento
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Hemostatics)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180102
[Lr] Data última revisão:
180102
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171228
[St] Status:MEDLINE
[do] DOI:10.1017/S0022215117002055


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[PMID]:28842996
[Au] Autor:Green R; Konuthula N; Sobrero M; Saini A; Parasher A; Pool C; Levine AI; DeMaria S; Tufts R; Govindaraj S; Iloreta AM
[Ad] Endereço:Department of Otolaryngology-Head and Neck Surgery, Icahn School of Medicine at Mount Sinai, New York, New York, U.S.A.
[Ti] Título:Use of pharyngeal packs in functional endoscopic sinus surgery: A randomized controlled trial.
[So] Source:Laryngoscope;127(11):2460-2465, 2017 Nov.
[Is] ISSN:1531-4995
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To determine if pharyngeal packs have an effect on postoperative pain and postoperative nausea and vomiting in functional endoscopic sinus surgery (FESS). STUDY DESIGN: Forty-six patients scheduled for routine endoscopic sinus surgery were recruited into this study. The patients were randomly allocated to have or to not have pharyngeal packing prior to surgery. METHODS: The placement of pharyngeal packs during FESS is controversial. Theoretically, pharyngeal packs may prevent postoperative nausea and vomiting by preventing ingestion of blood during sinus surgery. However, prior studies have not conclusively demonstrated this to be the case in FESS. Pharyngeal packs have been associated with complications including throat pain, aspiration, and death. The objective of this randomized control trial was to determine if pharyngeal packs have an effect on postoperative throat pain, nausea, and vomiting in order to determine their importance during FESS. Patients were blinded to intervention. Postoperatively, throat pain and nausea/vomiting scores were recorded. RESULTS: There was no significant difference in mean throat pain at 4 hours following surgery (P = 0.860). At 24 hours after surgery, patients without pharyngeal packing experienced more pain than those who had a throat pack placed (P = 0.002). There was no significant difference in the level of nausea at 4 hours after surgery (P = 0.315) or at 24 hours after surgery (P = 0.315). CONCLUSION: We recommend against the routine use of placing pharyngeal packs during FESS. LEVEL OF EVIDENCE: 1b. Laryngoscope, 127:2460-2465, 2017.
[Mh] Termos MeSH primário: Endoscopia/efeitos adversos
Faringe
Complicações Pós-Operatórias/prevenção & controle
Rinite/cirurgia
Sinusite/cirurgia
Tampões Cirúrgicos
[Mh] Termos MeSH secundário: Doença Crônica
Feminino
Seres Humanos
Masculino
Meia-Idade
Náusea/prevenção & controle
Dor Pós-Operatória/prevenção & controle
Náusea e Vômito Pós-Operatório/prevenção & controle
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171030
[Lr] Data última revisão:
171030
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170827
[St] Status:MEDLINE
[do] DOI:10.1002/lary.26651


  3 / 1387 MEDLINE  
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[PMID]:28693628
[Au] Autor:Bola S; Rashid M; Hickey S
[Ad] Endereço:Department of Otolaryngology,Torbay and South Devon NHS Foundation Trust,Torquay,UK.
[Ti] Título:Optimising the use of otowicks in otitis externa.
[So] Source:J Laryngol Otol;131(9):809-812, 2017 Sep.
[Is] ISSN:1748-5460
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: Otowicks are used to treat otitis externa with significant ear canal oedema. This study investigates how well drops penetrate through to reach the deep canal and whether it is safe to leave otowicks in the canal for more than 2 days. METHODS: Sterile otowicks were inserted into mock ear canals and vertically over pseudomonas-seeded agar plates whilst gentamicin or ciprofloxacin drops were administered. The time taken for drops to penetrate through the otowick was recorded. Separately, pseudomonas-seeded otowicks were treated with saline or antibacterial drops. The penetrating drops were observed for bacterial growth on sterile agar. RESULTS: It took six drops before penetration occurred for both antibiotics. When sterile saline drops were applied to bacterially contaminated otowicks, the penetrating drops displayed bacterial growth on agar, indicating that pseudomonas penetrated through the otowick. However, when antibiotic drops were applied, penetrating drops showed no bacterial growth on the corresponding agar plate. CONCLUSION: Bacteria can penetrate otowicks but this is prevented by continuous application of antibacterial ear drops. Ear wicks need priming with six drops before starting a regimen, so that the initial dose is fully absorbed.
[Mh] Termos MeSH primário: Ciprofloxacino/administração & dosagem
Gentamicinas/administração & dosagem
Otite Externa/tratamento farmacológico
[Mh] Termos MeSH secundário: Portadores de Fármacos
Seres Humanos
Instilação de Medicamentos
Otite Externa/metabolismo
Tampões Cirúrgicos
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Drug Carriers); 0 (Gentamicins); 5E8K9I0O4U (Ciprofloxacin)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170915
[Lr] Data última revisão:
170915
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170712
[St] Status:MEDLINE
[do] DOI:10.1017/S002221511700144X


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[PMID]:28631676
[Au] Autor:Mel'nikov MN; Val'ger AS
[Ad] Endereço:Novosibirsk State Medical University, Novosibirsk, Russia; The Centre of Novel Medical Technologies, Novosibirsk, Russia, 630090; City Children Clinical Emergency Care Hospital, Novosibirsk, Russia, 630007.
[Ti] Título:[The influence of nasal packing on the quality of life in the early postoperative period following septoplastic surgery].
[Ti] Título:Vliianie tamponady nosa na kachestvo zhizni v rannem posleoperatsionnom periode posle septoplastiki..
[So] Source:Vestn Otorinolaringol;82(3):28-30, 2017.
[Is] ISSN:0042-4668
[Cp] País de publicação:Russia (Federation)
[La] Idioma:rus
[Ab] Resumo:The objective of the present study was to evaluate the influence of anterior nasal packing on the physical health condition and the quality of life of the patients in the early postoperative period following septoplastic surgery and to propose an alternative to the anterior nasal packing procedure. The study included 90 patients divided into three groups. Those of the first group underwent endoscopic septoplasty, the patients of the second group were managed by standard septoplastic surgery, and the patients of group 3 were given treatment with the use of modified septoplasty including the application of a fibrin sealant as an alternative to nasal tampons. It was shown that anterior nasal packing exerts the undesirable influence on the quality of life during the early postoperative period following septoplastic surgery whereas the use of the modified technique based on the application of a fibrin sealant as an alternative therapeutic modality significantly enhances the effectiveness of the treatment.
[Mh] Termos MeSH primário: Adesivo Tecidual de Fibrina/uso terapêutico
Septo Nasal/cirurgia
Cuidados Pós-Operatórios
Hemorragia Pós-Operatória
Qualidade de Vida
Rinoplastia
[Mh] Termos MeSH secundário: Adulto
Pesquisa Comparativa da Efetividade
Feminino
Técnicas Hemostáticas/instrumentação
Hemostáticos/uso terapêutico
Seres Humanos
Masculino
Cuidados Pós-Operatórios/instrumentação
Cuidados Pós-Operatórios/métodos
Cuidados Pós-Operatórios/psicologia
Hemorragia Pós-Operatória/diagnóstico
Hemorragia Pós-Operatória/prevenção & controle
Período Pós-Operatório
Rinoplastia/efeitos adversos
Rinoplastia/métodos
Tampões Cirúrgicos/efeitos adversos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Fibrin Tissue Adhesive); 0 (Hemostatics)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170927
[Lr] Data última revisão:
170927
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170621
[St] Status:MEDLINE
[do] DOI:10.17116/otorino201782328-30


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[PMID]:27885513
[Au] Autor:Kayahan B; Ozer S; Suslu AE; Ogretmenoglu O; Onerci M
[Ad] Endereço:Ear Nose Throat-Head and Neck Surgery Clinic, Etimesgut Sait Ertürk State Hospital, Ankara, Turkey. baharkayahan@hotmail.com.
[Ti] Título:The comparison of the quality of life and intranasal edema between the patients with or without nasal packing after septoplasty.
[So] Source:Eur Arch Otorhinolaryngol;274(3):1551-1555, 2017 Mar.
[Is] ISSN:1434-4726
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Septoplasty is one of the most common operations performed in otolaryngology and anterior nasal packing is done routinely to prevent postoperative bleeding, septal hematoma or nasal synechia. Currently, transseptal sutures have gained a broader application area, not only for preventing the complications such as septal hematoma and bleeding but also closing any accidental tears of septal mucosa and providing additional support for the cartilage pieces retained in septoplasty. We evaluated the quality of life of the patients in early postoperative period (in the first postoperative week), intranasal edema with endoscopic examination and the intranasal changes with acoustic rhinometry. We performed a prospective and randomized study with patients undergoing septoplasty without inferior turbinectomy. As packing material, there were two groups: in group A, gauze in a glove finger and in group B, Doyle splint were used, and in the additional group C, only transseptal suture with 4/0 vicryl among the cartilaginous septum was performed. The patients were invited to control examinations on the postoperative 2nd, 4th and 7th days to evaluate the scores from 1 to 5 on the questionnaire for the pain, nasal fullness, sneezing, epiphora, difficulty in swallowing and sleep disturbances. The patients were also administered an endoscopic nasal examination for the purpose of detecting the intranasal edema, and acoustic rhinometry was performed during the control examinations to detect the intranasal changes. Total occluding packing was found to cause much more frequent and higher scores of epiphora, sneezing, difficulty in swallowing, but mainly, the pain compared to in silicone packing with airway and transseptal suture only. Although the silicone packing with airway was found to be much more comfortable, it also led to sneezing and epiphora. The patients without nasal packing had more comfortable period especially in the early postoperative days (the first 4 days). However, 1 week after surgery, groups with and without nasal packing were found to be equalized on behalf of the objective and subjective parameters. As any complication was not observed due to not using nasal packing, it is thought that nasal packing usage following septoplasty is not a necessity.
[Mh] Termos MeSH primário: Edema
Septo Nasal/cirurgia
Hemorragia Pós-Operatória/prevenção & controle
Qualidade de Vida
Rinoplastia/efeitos adversos
Tampões Cirúrgicos/efeitos adversos
[Mh] Termos MeSH secundário: Administração Intranasal
Adulto
Edema/diagnóstico
Edema/etiologia
Edema/psicologia
Emigração e Imigração
Feminino
Seres Humanos
Masculino
Meia-Idade
Rinometria Acústica/métodos
Rinoplastia/métodos
Inquéritos e Questionários
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170928
[Lr] Data última revisão:
170928
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161126
[St] Status:MEDLINE
[do] DOI:10.1007/s00405-016-4403-9


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[PMID]:27864671
[Au] Autor:Sevik Eliçora S; Erdem D; Dinç AE; Altunordu Kalayci Ö; Hazer B; Yurdakan G; Külah C
[Ad] Endereço:Department of Otorhinolaryngology, Faculty of Medicine, Bülent Ecevit University, Zonguldak, Turkey. drsultan@mynet.com.
[Ti] Título:Effects of polymer-based, silver nanoparticle-coated silicone splints on the nasal mucosa of rats.
[So] Source:Eur Arch Otorhinolaryngol;274(3):1535-1541, 2017 Mar.
[Is] ISSN:1434-4726
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Infection is a serious complication after nasal packing that otolaryngologists seek to avoid. The aim of this study is to investigate the use of silver (Ag) nanoparticle, which serves as antimicrobial agents, with nasal tampons. The study design is an experimental animal model and the setting is tertiary referral center. Twenty-four rats were randomized into the following four groups: (1) control group (n = 6); (2) silicone nasal splint (SNS) group (n  =  6); (3) polypropylene-grafted polyethylene glycol (PP-g-PEG) amphiphilic graft copolymer-coated SNS group (n  =  6); and (4) Ag nanoparticle-embedded PP-g-PEG (Ag-PP-g-PEG) amphiphilic graft copolymer-coated SNS group (n  =  6). These tampons were applied to rats for 48 h, after which they were removed in a sterile manner, and the rats were sacrificed. The nasal septa of the rats were excised, and assessments of tissue changes in the nasal mucosa were compared among the groups. The removed tampons were microbiologically examined, and quantitative analyses were made. When the groups were compared microbiologically, there were no significant differences in bacterial colonization rates of coagulase-negative Staphylococcus spp. among the three groups (p = 0.519), but there was a statistically significant difference among bacterial colonization rates of Heamophilus parainfluenzae and Corynebacterium spp. (p = 0.018, p = 0.004). We found that H. parainfluenzae grew less robustly in the Ag-PP-g-PEG than the PP-g-PEG group (p = 0.017). However, we found no significant difference between the Ag-PP-g-PEG and SNS groups, or between the SNS and PP-g-PEG groups. The growth of Corynebacterium spp. did not differ significantly between the Ag-PP-g-PEG and SNS groups (p = 1.000). When Group 4 was compared with Group 2, the former showed less inflammation. Compared with other tampons, Ag-PP-g-PEG amphiphilic graft copolymer-coated silicone nasal tampons caused less microbiological colonization and inflammation. Therefore, the use of these tampons may prevent secondary infections and reduce the risk of developing complications by minimizing tissue damage.
[Mh] Termos MeSH primário: Nanopartículas Metálicas
Procedimentos Cirúrgicos Nasais/instrumentação
Silicones/farmacologia
Prata/farmacologia
Contenções
Infecção da Ferida Cirúrgica/prevenção & controle
[Mh] Termos MeSH secundário: Animais
Antibacterianos/farmacologia
Modelos Animais de Doenças
Masculino
Mucosa Nasal/efeitos dos fármacos
Septo Nasal/cirurgia
Procedimentos Cirúrgicos Nasais/efeitos adversos
Procedimentos Cirúrgicos Nasais/métodos
Ratos
Tampões Cirúrgicos/efeitos adversos
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); 0 (Silicones); 3M4G523W1G (Silver)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170928
[Lr] Data última revisão:
170928
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161120
[St] Status:MEDLINE
[do] DOI:10.1007/s00405-016-4394-6


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[PMID]:27837422
[Au] Autor:Sireci F; Speciale R; Sorrentino R; Turri-Zanoni M; Nicolotti M; Canevari FR
[Ad] Endereço:Otorhinolaryngology Section, Department of Experimental Biomedicine and Clinical Neurosciences (BioNeC), University of Palermo, via del Vespro 129, 90127, Palermo, Italy. federicosireci@hotmail.it.
[Ti] Título:Nasal packing in sphenopalatine artery bleeding: therapeutic or harmful?
[So] Source:Eur Arch Otorhinolaryngol;274(3):1501-1505, 2017 Mar.
[Is] ISSN:1434-4726
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:The aim of this study is to present our management protocol of sphenopalatine artery bleeding, demonstrating that nasoendoscopic cautery (NC) was a more effective method than the nasal packing, in terms of shorter inpatient stay and reduced complications rate. We present ten posterior epistaxis not resolved by nasal packing. Tabotamp was placed in the area of sphenopalatine foramen and/or in those parts of the posterior nasal cavity, where it was suspected that bleeding origins. In two cases, the bleeding was resolved in this way, instead eight cases needed of subperiosteal cauterization of sphenopalatine artery by Dessi bipolar forceps (MicroFrance ). 4 of these 8 patients evidenced a remarkable bleeding removing nasal packing (Hb before-nasal packing = 15 ± 0.69 versus Hb after-nasal packing = 13.3 ± 0.81; t student = 2.94; p value = 0.025). These four patients showed a deviation of the nasal septum ipsilateral to epistaxis, and according our experience, a traumatism of sphenopalatine area can be caused by Merocel nasal packing in this condition. During follow-up, no recurrences of nasal bleeding have been observed in such patients. Nasal packing must be considered if posterior epistaxis is severe, but always taking into account the specific anatomy of patient and in particular septal spurs that can further compromise sphenopalatine artery. In our experience, the endoscopic endonasal cauterization of the sphenopalatine branches represented a safe and effective procedure.
[Mh] Termos MeSH primário: Artérias/cirurgia
Bandagens/efeitos adversos
Eletrocoagulação
Epistaxe/terapia
Tampões Cirúrgicos
[Mh] Termos MeSH secundário: Idoso
Idoso de 80 Anos ou mais
Endoscopia
Epistaxe/etiologia
Feminino
Seres Humanos
Tempo de Internação
Masculino
Meia-Idade
Cavidade Nasal/irrigação sanguínea
Septo Nasal/lesões
Estudos Retrospectivos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170928
[Lr] Data última revisão:
170928
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161113
[St] Status:MEDLINE
[do] DOI:10.1007/s00405-016-4381-y


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[PMID]:27371330
[Au] Autor:Nomura K; Yamanaka Y; Sekine Y; Yamamoto H; Esu Y; Hara M; Hasegawa M; Shinnabe A; Kanazawa H; Kakuta R; Ozawa D; Hidaka H; Katori Y; Yoshida N
[Ad] Endereço:Department of Otolaryngology, Jichi Medical University, Saitama Medical Center, Saitama, Japan. kazuhiroe@gmail.com.
[Ti] Título:Predicting postoperative fever and bacterial colonization on packing material following endoscopic endonasal surgery.
[So] Source:Eur Arch Otorhinolaryngol;274(1):167-173, 2017 Jan.
[Is] ISSN:1434-4726
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Postoperative fever following endoscopic endonasal surgery is a rare occurrence of concern to surgeons. To elucidate preoperative and operative predictors of postoperative fever, we analyzed the characteristics of patients and their perioperative background in association with postoperative fever. A retrospective review of 371 patients who had undergone endoscopic endonasal surgery was conducted. Predictors, including intake of antibiotics, steroids, history of asthma, preoperative nasal bacterial culture, duration of operation, duration of packing and intraoperative intravenous antibiotics on the occurrence of postoperative fever, and bacterial colonization on the packing material, were analyzed retrospectively. Fever (≥38 °C) occurred in 63 (17 %) patients. Most incidences of fever occurred on postoperative day one. In majority of these cases, the fever subsided after removal of the packing material without further antibiotic administration. However, one patient who experienced persistent fever after the removal of packing material developed meningitis. History of asthma, prolonged operation time (≥108 min), and intravenous cefazolin administration instead of cefmetazole were associated with postoperative fever. Odds ratios (ORs) for each were 2.3, 4.6, and 2.0, respectively. Positive preoperative bacterial colonization was associated with postoperative bacterial colonization on the packing material (OR 2.3). Postoperative fever subsided in most patients after removal of the packing material. When this postoperative fever persists, its underlying cause should be examined.
[Mh] Termos MeSH primário: Endoscopia
Febre/etiologia
Cavidade Nasal/cirurgia
Complicações Pós-Operatórias
Tampões Cirúrgicos/microbiologia
[Mh] Termos MeSH secundário: Antibacterianos/administração & dosagem
Antibioticoprofilaxia
Asma/complicações
Cefazolina/administração & dosagem
Cefmetazol/administração & dosagem
Feminino
Seres Humanos
Masculino
Meningite/etiologia
Meia-Idade
Cavidade Nasal/microbiologia
Duração da Cirurgia
Estudos Retrospectivos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); 3J962UJT8H (Cefmetazole); IHS69L0Y4T (Cefazolin)
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170928
[Lr] Data última revisão:
170928
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160703
[St] Status:MEDLINE
[do] DOI:10.1007/s00405-016-4189-9


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[PMID]:28661608
[Au] Autor:Mikhaylusov RN
[Ti] Título:[[Spongy microporous tampon for mechanical clearance of a gun-shot wounos].]
[So] Source:Klin Khir;(8):57-59, 2016 Aug.
[Is] ISSN:0023-2130
[Cp] País de publicação:Ukraine
[La] Idioma:rus
[Ab] Resumo:Application of a spongy microporous tampon in accordance to technology elaborated was proposed for enhancement of the mechanical clearance efficacy of the gun-shot soft tissues wounds. A procedure of manufacturing and application of spongy microp- orous tampon for the mechanical clearance of a gun-shot wounds was depicted. The clearance efficacy was improved due to application of the method elaborated, wit- nessing possibility of its usage on all stages of the surgical aid delivery.
[Mh] Termos MeSH primário: Anti-Infecciosos Locais/uso terapêutico
Tampões Cirúrgicos
Ferimentos por Arma de Fogo/terapia
Ferimentos Penetrantes/terapia
[Mh] Termos MeSH secundário: Adulto
Idoso
Seres Humanos
Masculino
Meia-Idade
Porosidade
Lesões dos Tecidos Moles
Resultado do Tratamento
Molhabilidade
Ferimentos por Arma de Fogo/cirurgia
Ferimentos Penetrantes/cirurgia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Infective Agents, Local)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170907
[Lr] Data última revisão:
170907
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170630
[St] Status:MEDLINE


  10 / 1387 MEDLINE  
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[PMID]:28005800
[Au] Autor:Gokdogan O; Kizil Y; Akyildiz I; Ahlat O; Kalkanci A; Uslu S; Ileri F
[Ad] Endereço:*Department of Otorhinolaryngology, Memorial Health Group Ankara Hospital†Department of Otorhinolaryngology, Gazi University Hospital‡Department of Otorhinolaryngology, Ankara Research and Teaching Hospital§Department of Pathology, Ankara University Faculty of Veterinary of Medicine||Department of Microbiology, Gazi University Hospital, Ankara, Turkey.
[Ti] Título:Microbiological and Histopathological Effects of Nasal Packing Containing Probiotics on Nasal Mucosa.
[So] Source:J Craniofac Surg;27(8):e730-e734, 2016 Nov.
[Is] ISSN:1536-3732
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Nasal packing is frequently used after surgical interventions to prevent bleeding and synecchia formation and for the treatment of diseases such as epistaxis. One of the most morbid complications of nasal packing applications is the toxic shock syndrome (TSS). Owing to the microbiological structure of nasal mucosa, antibiotics are administered to all patients who are applied nasal packages for prevention of TSS. AIM: The aim of this study is the evaluation of microbiological and histopathological changes taking place in nasal mucosa with nasal packing containing probiotics. METHODS: Three groups were formed with 6 rats in each group. The nasal packings with the same characteristics were applied to nasal cavities of rats in all 3 groups. In group 1, only nasal packs were used. Probiotics or parenteral antibiotics were not used. In group 2, parenteral antibiotics were used along with nasal packs. In group 3, nasal packs with probiotics containing Lactobacillus strains were applied. No parenteral antibiotics were used. After 3 days packages were removed and nasal cavity was irrigated with saline. Both packages and irrigation materials were analyzed for microbiological content. After scarification, nasal and paranasal structures were examined for histopathological changes. RESULTS: In group 3 statistically the total bacteria load was significantly lower in comparison to the other groups. However, in the histopathological evaluation of the mucosa of rats in group 3, bleeding and inflammation findings were significantly higher statistically. CONCLUSIONS: It has been determined that the total microbiological load significantly decreases with the application of packing containing probiotics. So, the use of probiotics along with nasal packings is promising to prevent unnecessary use of medications.
[Mh] Termos MeSH primário: Antibacterianos/farmacologia
Epistaxe/terapia
Técnicas Hemostáticas/instrumentação
Cavidade Nasal/efeitos dos fármacos
Probióticos/farmacologia
Tampões Cirúrgicos
[Mh] Termos MeSH secundário: Animais
Modelos Animais de Doenças
Epistaxe/etiologia
Feminino
Masculino
Ratos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Bacterial Agents)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:D
[Da] Data de entrada para processamento:161223
[St] Status:MEDLINE
[do] DOI:10.1097/SCS.0000000000003061



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