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Pesquisa : F01.145.113.780 [Categoria DeCS]
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  1 / 20 MEDLINE  
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[PMID]:28716951
[Au] Autor:Land M; Rubin CS
[Ad] Endereço:Department of Molecular Pharmacology, Atran Laboratories, Albert Einstein College of Medicine, Bronx, New York, USA.
[Ti] Título:A Calcium- and Diacylglycerol-Stimulated Protein Kinase C (PKC), Caenorhabditis elegans PKC-2, Links Thermal Signals to Learned Behavior by Acting in Sensory Neurons and Intestinal Cells.
[So] Source:Mol Cell Biol;37(19), 2017 Oct 01.
[Is] ISSN:1098-5549
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Ca - and diacylglycerol (DAG)-activated protein kinase C (cPKC) promotes learning and behavioral plasticity. However, knowledge of regulation and exact functions of cPKCs that affect behavior is limited. We show that PKC-2, a cPKC, is essential for a complex behavior, thermotaxis. memorizes a nutrient-associated cultivation temperature ( ) and migrates along the within a 17 to 25°C gradient. gene disruption abrogated thermotaxis; a PKC-2 transgene, driven by endogenous promoters, restored thermotaxis behavior in animals. Cell-specific manipulation of PKC-2 activity revealed that thermotaxis is controlled by cooperative PKC-2-mediated signaling in both AFD sensory neurons and intestinal cells. Cold-directed migration (cryophilic drive) precedes tracking during thermotaxis. Analysis of temperature-directed behaviors elicited by persistent PKC-2 activation or inhibition in AFD (or intestine) disclosed that PKC-2 regulates initiation and duration of cryophilic drive. In AFD neurons, PKC-2 is a Ca sensor and signal amplifier that operates downstream from cyclic GMP-gated cation channels and distal guanylate cyclases. UNC-18, which regulates neurotransmitter and neuropeptide release from synaptic vesicles, is a critical PKC-2 effector in AFD. UNC-18 variants, created by mutating Ser or Ser , disrupt thermotaxis and suppress PKC-2-dependent cryophilic migration.
[Mh] Termos MeSH primário: Proteínas de Caenorhabditis elegans/metabolismo
Caenorhabditis elegans/fisiologia
Intestinos/metabolismo
Proteína Quinase C/metabolismo
Células Receptoras Sensoriais/metabolismo
Resposta Táctica/fisiologia
[Mh] Termos MeSH secundário: Animais
Comportamento Animal/fisiologia
Proteínas de Caenorhabditis elegans/genética
Temperatura Baixa
Mutação
Fosfoproteínas/genética
Fosfoproteínas/metabolismo
Proteína Quinase C/genética
Transdução de Sinais
Proteínas de Transporte Vesicular/genética
Proteínas de Transporte Vesicular/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Caenorhabditis elegans Proteins); 0 (Phosphoproteins); 0 (Unc-18 protein, C elegans); 0 (Vesicular Transport Proteins); EC 2.7.11.13 (PKC-2 protein, C elegans); EC 2.7.11.13 (Protein Kinase C)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171003
[Lr] Data última revisão:
171003
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170719
[St] Status:MEDLINE


  2 / 20 MEDLINE  
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[PMID]:28686708
[Au] Autor:Chang JC; Morton DB
[Ad] Endereço:Department of Integrative Biosciences, Oregon Health & Science University, Portland, Oregon, United States of America.
[Ti] Título:Drosophila lines with mutant and wild type human TDP-43 replacing the endogenous gene reveals phosphorylation and ubiquitination in mutant lines in the absence of viability or lifespan defects.
[So] Source:PLoS One;12(7):e0180828, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Mutations in TDP-43 are associated with proteinaceous inclusions in neurons and are believed to be causative in neurodegenerative diseases such as frontotemporal dementia or amyotrophic lateral sclerosis. Here we describe a Drosophila system where we have engineered the genome to replace the endogenous TDP-43 orthologue with wild type or mutant human TDP-43(hTDP-43). In contrast to other models, these flies express both mutant and wild type hTDP-43 at similar levels to those of the endogenous gene and importantly, no age-related TDP-43 accumulation observed among all the transgenic fly lines. Immunoprecipitation of TDP-43 showed that flies with hTDP-43 mutations had increased levels of ubiquitination and phosphorylation of the hTDP-43 protein. Furthermore, histologically, flies expressing hTDP-43 M337V showed global, robust neuronal staining for phospho-TDP. All three lines: wild type hTDP-43, -G294A and -M337V were homozygous viable, with no defects in development, life span or behaviors observed. The primary behavioral defect was that flies expressing either hTDP-43 G294A or M337V showed a faster decline with age in negative geotaxis. Together, these observations implied that neurons could handle these TDP-43 mutations by phosphorylation- and ubiquitin-dependent proteasome systems, even in a background without the wild type TDP-43. Our findings suggest that these two specific TDP-43 mutations are not inherently toxic, but may require additional environmental or genetic factors to affect longevity or survival.
[Mh] Termos MeSH primário: Envelhecimento/metabolismo
Proteínas de Ligação a DNA/metabolismo
Drosophila melanogaster/genética
Longevidade
Neurônios/metabolismo
Processamento de Proteína Pós-Traducional
[Mh] Termos MeSH secundário: Animais
Animais Geneticamente Modificados
Proteínas de Ligação a DNA/genética
Drosophila melanogaster/crescimento & desenvolvimento
Drosophila melanogaster/metabolismo
Feminino
Seres Humanos
Masculino
Mutação
Neurônios/citologia
Fosforilação
Transdução de Sinais
Resposta Táctica/fisiologia
Transgenes
Ubiquitinação
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA-Binding Proteins); 0 (TDP-43 protein, human)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170922
[Lr] Data última revisão:
170922
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170708
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0180828


  3 / 20 MEDLINE  
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Lazzari, Claudio R
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[PMID]:28479122
[Au] Autor:Zermoglio PF; Robuchon E; Leonardi MS; Chandre F; Lazzari CR
[Ad] Endereço:Departamento de Ecología, Genética y Evolución, Instituto IEGEBA (CONICET-UBA), Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Argentina; Institut de Recherche sur la Biologie de l'Insecte, UMR CNRS 7261, Université François Rabelais, Tours, France. Electronic address: pzermo
[Ti] Título:What does heat tell a mosquito? Characterization of the orientation behaviour of Aedes aegypti towards heat sources.
[So] Source:J Insect Physiol;100:9-14, 2017 Jul.
[Is] ISSN:1879-1611
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The use of heat as a cue for the orientation of haematophagous insects towards hot-blooded hosts has been acknowledged for many decades. In mosquitoes, thermoreception has been studied at the molecular, physiological and behavioural levels, and the response to heat has been evaluated in multimodal contexts. However, a direct characterization of how these insects evaluate thermal sources is still lacking. In this study we characterize Aedes aegypti thermal orientation using a simple dual choice paradigm, providing direct evidence on how different attributes of heat sources affect their choice. We found that female mosquitoes, but not males, are able to discriminate among heat sources that are at ambient, host-range and deleterious temperatures when no other stimuli are present, eliciting a positive response towards host-range and an avoidance response towards deleterious temperatures. We also tested the preference of females according to the size and position of the sources. We found that females do not discriminate between heat sources of different sizes, but actively orientate towards closer sources at host temperature. Furthermore, we show that females cannot use IR radiation as an orientation cue. Orientation towards a host involves the integration of cues of different nature in distinct phases of the orientation. Although such integration might be decisive for successful encounter of the host, we show that heat alone is sufficient to elicit orientation behaviour. We discuss the performance of mosquitoes' thermal behaviour compared to other blood-sucking insects.
[Mh] Termos MeSH primário: Aedes/fisiologia
Sinais (Psicologia)
[Mh] Termos MeSH secundário: Animais
Feminino
Temperatura Alta
Orientação Espacial
Resposta Táctica
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170928
[Lr] Data última revisão:
170928
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170509
[St] Status:MEDLINE


  4 / 20 MEDLINE  
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[PMID]:28429325
[Au] Autor:Häder DP; Hemmersbach R
[Ad] Endereço:Department of Biology, Friedrich-Alexander Universität, Erlangen-Nürnberg, Neue Str. 9, 91096, Möhrendorf, Germany. donat@dphaeder.de.
[Ti] Título:Gravitaxis in Euglena.
[So] Source:Adv Exp Med Biol;979:237-266, 2017.
[Is] ISSN:0065-2598
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Motile microorganisms utilize a number of responses to external stimuli including light, temperature, chemicals as well as magnetic and electric fields. Gravity is a major clue to select a niche in their environment. Positive gravitaxis leads an organism down into the water column and negative gravitaxis brings it to the surface. In Euglena the precision of gravitaxis is regulated by an internal rhythm entrained by the daily light/dark cycle. This and the cooperation with phototaxis bring the cells into an optimal position in the water column. In the past a passive orientation based on a buoy mechanism has been proposed for Euglena gracilis, but now it has been proven that this flagellate possesses a physiological gravireceptor and an active orientation. Numerous experiments in space using satellites, rockets and shuttles as well as in parabolic flights have been conducted as well as in functional weightlessness (simulated microgravity) on ground-based facilities such as clinostats to characterize the gravitaxis of Euglena. The threshold for gravity perception was determined and physiological, biochemical and molecular components of the signal transduction chain have been identified. In contrast to higher plants, some algae and ciliates, Euglena does not possess sedimenting statoliths to detect the direction of the gravity vector of the Earth. The gravireceptors were found to be mechano-sensitive Ca -conducting ion channels thought to be located at the front end of the cell underneath the trailing flagellum. When activated by gravity-induced pressure due to sedimentation of the whole cell body, they allow a passive influx of calcium along a previously established ion gradient. The entering calcium binds to a specific calmodulin (CaM.2) which in turn activates an adenylyl cyclase producing cAMP from ATP. This cAMP is believed to activate a specific protein kinase A (PK.4), which is postulated to phosphorylate proteins inside the flagellum resulting in a bending and thus a course correction and reorientation with respect to the direction of the gravity vector. The elements of the signal transduction chain have been characterized by inhibitors and by RNAi to prove their involvement in gravitaxis.
[Mh] Termos MeSH primário: Sinalização do Cálcio/fisiologia
Euglena/fisiologia
Flagelos/metabolismo
Gravitação
Proteínas de Protozoários/metabolismo
Resposta Táctica/fisiologia
[Mh] Termos MeSH secundário: Flagelos/genética
Proteínas de Protozoários/genética
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T; REVIEW
[Nm] Nome de substância:
0 (Protozoan Proteins)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171024
[Lr] Data última revisão:
171024
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170422
[St] Status:MEDLINE
[do] DOI:10.1007/978-3-319-54910-1_12


  5 / 20 MEDLINE  
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[PMID]:28399312
[Au] Autor:Jakhete SS; Allan SA; Mankin RW
[Ad] Endereço:US Department of Agriculture, Agricultural Research Service, Center for Medical, Agricultural, and Veterinary Entomology, Gainesville, FL 32608.
[Ti] Título:Wingbeat Frequency-Sweep and Visual Stimuli for Trapping Male Aedes aegypti (Diptera: Culicidae).
[So] Source:J Med Entomol;54(5):1415-1419, 2017 Sep 01.
[Is] ISSN:1938-2928
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Combinations of female wingbeat acoustic cues and visual cues were evaluated to determine their potential for use in male Aedes aegypti (L.) traps in peridomestic environments. A modified Centers for Disease control (CDC) light trap using a 350-500 Hz frequency-sweep broadcast from a speaker as an acoustic stimulus, combined with a black poster-board half-cylinder behind the trap as a visual stimulus, captured a significantly greater proportion of males in a laboratory arena during daylight than a CDC trap with the visual stimulus alone or a CDC trap alone without stimuli. Traps of each treatment type captured relatively more males when they were placed at darker positions in the arena. Potential applications are discussed for the incorporation of these findings into trapping programs to reduce transmission of human pathogens vectored by Ae. aegypti.
[Mh] Termos MeSH primário: Estimulação Acústica
Aedes/fisiologia
Voo Animal
Controle de Mosquitos/métodos
Estimulação Luminosa
[Mh] Termos MeSH secundário: Animais
Sinais (Psicologia)
Masculino
Resposta Táctica
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170922
[Lr] Data última revisão:
170922
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170412
[St] Status:MEDLINE
[do] DOI:10.1093/jme/tjx074


  6 / 20 MEDLINE  
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[PMID]:28215941
[Au] Autor:Amon S; Gupta BP
[Ad] Endereço:Department of Biology, McMaster University, Hamilton, ON, Canada L8S-4K1.
[Ti] Título:Intron-specific patterns of divergence of lin-11 regulatory function in the C. elegans nervous system.
[So] Source:Dev Biol;424(1):90-103, 2017 04 01.
[Is] ISSN:1095-564X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The diversity of neurons in the nervous system is specified by many genes, including those that encode transcription factors (TFs) and play crucial roles in coordinating gene transcription. To understand how the spatiotemporal expression of TF genes is regulated to generate neuronal diversity, we used one member of the LIM-Hox family, lin-11, as a model that is necessary for the differentiation of amphid neurons in the nematode C. elegans and a related species C. briggsae. We characterized transcriptional regulation of lin-11 and uncovered regulatory roles of two of the largest introns, intron 3 and intron 7. These introns promote lin-11 expression in non-overlapping sets of neurons. Phenotypic rescue experiments in C. elegans revealed that intron 3 is capable of restoring lin-11 function based on gene expression patterns and behavioral assays. Interestingly, intron 3-driven reporter expression showed differences in neuronal cell types between C. briggsae and C. elegans, indicating evolutionary changes in lin-11 regulation between the two species. Reciprocal transformation experiments provided further evidence consistent with functional changes in both cis and trans regulation of lin-11. To further investigate transcriptional regulation of lin-11, we dissected the intronic regions in C. elegans and identified cell-specific enhancers. These enhancers possess multiple sequence blocks that are conserved among Caenorhabditis species and possess TF binding sites. We tested the role of a subset of predicted TFs and discovered that while three of them (SKN-1, CEH-6, and CRH-1) act via the intron 3 enhancer to negatively regulate lin-11 expression in neurons, another TF (CES-1) acts positively via the intron 7 enhancer. Overall, our findings demonstrate that neuronal expression of lin-11 involves multiple TF regulators and regulatory modules some of which have diverged in Caenorhabditis nematodes.
[Mh] Termos MeSH primário: Proteínas de Caenorhabditis elegans/metabolismo
Caenorhabditis elegans/genética
Proteínas de Homeodomínio/metabolismo
Íntrons/genética
Sistema Nervoso/metabolismo
[Mh] Termos MeSH secundário: Animais
Sequência de Bases
Proteínas de Caenorhabditis elegans/genética
Sequência Conservada/genética
Eletricidade
Elementos Facilitadores Genéticos/genética
Evolução Molecular
Regulação da Expressão Gênica no Desenvolvimento
Proteínas de Fluorescência Verde/metabolismo
Proteínas de Homeodomínio/genética
Modelos Biológicos
Mutação/genética
Neurônios/metabolismo
Resposta Táctica
Fatores de Transcrição/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Caenorhabditis elegans Proteins); 0 (Homeodomain Proteins); 0 (Lin-11 protein, C elegans); 0 (Transcription Factors); 147336-22-9 (Green Fluorescent Proteins)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:171110
[Lr] Data última revisão:
171110
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170221
[St] Status:MEDLINE


  7 / 20 MEDLINE  
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[PMID]:27323374
[Au] Autor:Choiniere JP; Gosselin C
[Ti] Título:Development and Experimental Validation of a Haptic Compass Based on Asymmetric Torque Stimuli.
[So] Source:IEEE Trans Haptics;10(1):29-39, 2017 Jan-Mar.
[Is] ISSN:2329-4051
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:This paper presents the design, control, and experimental validation of a haptic compass, designed as a guiding device for all environments. The proposed device uses the principle of asymmetric torques. Its design is based on a direct drive motor and a pre-calibrated open-loop control, which allows the generation of stimuli in a wide range of frequencies. User studies are presented and show optimum effectiveness in the frequency range 5-15 Hz and for torques over 40 mNm. The use of a haptic feedback proportional to the angle error is then shown to significantly improve the results. An experimental validation by a group of' subjects with the portable device using these stimuli is reported. The results show that all subjects met all route objectives with small lateral deviations (avg. 0.39 m).
[Mh] Termos MeSH primário: Resposta Táctica/fisiologia
[Mh] Termos MeSH secundário: Adulto
Algoritmos
Simulação por Computador
Desenho de Equipamento
Feminino
Seres Humanos
Masculino
Meia-Idade
Torque
Interface Usuário-Computador
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170929
[Lr] Data última revisão:
170929
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160621
[St] Status:MEDLINE
[do] DOI:10.1109/TOH.2016.2580144


  8 / 20 MEDLINE  
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[PMID]:27992447
[Au] Autor:De Toni L; Garolla A; Menegazzo M; Magagna S; Di Nisio A; Sabovic I; Rocca MS; Scattolini V; Filippi A; Foresta C
[Ad] Endereço:Department of Medicine, Unit of Andrology and Reproductive Medicine, University of Padova, Via Giustiniani, Padova, Italy.
[Ti] Título:Heat Sensing Receptor TRPV1 Is a Mediator of Thermotaxis in Human Spermatozoa.
[So] Source:PLoS One;11(12):e0167622, 2016.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The molecular bases of sperm thermotaxis, the temperature-oriented cell motility, are currently under investigation. Thermal perception relies on a subclass of the transient receptor potential [TRP] channels, whose member TRPV1 is acknowledged as the heat sensing receptor. Here we investigated the involvement of TRPV1 in human sperm thermotaxis. We obtained semen samples from 16 normozoospermic subjects attending an infertility survey programme, testis biopsies from 6 patients with testicular germ cell cancer and testis fine needle aspirates from 6 patients with obstructive azoospermia undergoing assisted reproductive technologies. Expression of TRPV1 mRNA was assessed by RT-PCR. Protein expression of TRPV1 was determined by western blot, flow cytometry and immunofluorescence. Sperm motility was assessed by Sperm Class Analyser. Acrosome reaction, apoptosis and intracellular-Ca2+ content were assessed by flow cytometry. We found that TRPV1 mRNA and protein were highly expressed in the testis, in both Sertoli cells and germ-line cells. Moreover, compared to no-gradient controls at 31°C or 37°C (Ctrl 31°C and Ctrl 37°C respectively), sperm migration towards a temperature gradient of 31-37°C (T gradient) in non-capacitated conditions selected a higher number of cells (14,9 ± 4,2×106 cells T gradient vs 5,1± 0,3×106 cells Ctrl 31°C and 5,71±0,74×106 cells Ctrl 37°C; P = 0,039). Capacitation amplified the migrating capability towards the T gradient. Sperms migrated towards the T gradient showed enriched levels of both TRPV1 protein and mRNA. In addition, sperm cells were able to migrate toward a gradient of capsaicin, a specific agonist of TRPV1, whilst capsazepine, a specific agonist of TRPV1, blocked this effect. Finally, capsazepine severely blunted migration towards T gradient without abolishing. These results suggest that TRPV1 may represent a facilitating mediator of sperm thermotaxis.
[Mh] Termos MeSH primário: Infertilidade Masculina/genética
Neoplasias Embrionárias de Células Germinativas/genética
Espermatozoides/fisiologia
Canais de Cátion TRPV/genética
Resposta Táctica
Neoplasias Testiculares/genética
[Mh] Termos MeSH secundário: Adulto
Azoospermia/genética
Azoospermia/metabolismo
Azoospermia/patologia
Capsaicina/análogos & derivados
Capsaicina/farmacologia
Seres Humanos
Infertilidade Masculina/metabolismo
Infertilidade Masculina/patologia
Masculino
Neoplasias Embrionárias de Células Germinativas/metabolismo
Neoplasias Embrionárias de Células Germinativas/patologia
Motilidade Espermática
Espermatozoides/efeitos dos fármacos
Espermatozoides/metabolismo
Canais de Cátion TRPV/metabolismo
Resposta Táctica/efeitos dos fármacos
Neoplasias Testiculares/metabolismo
Neoplasias Testiculares/patologia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (TRPV Cation Channels); 0 (TRPV1 protein, human); LFW48MY844 (capsazepine); S07O44R1ZM (Capsaicin)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170713
[Lr] Data última revisão:
170713
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161220
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0167622


  9 / 20 MEDLINE  
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[PMID]:27688050
[Au] Autor:DeVries ZC; Mick R; Schal C
[Ad] Endereço:Department of Entomology and Plant Pathology, and W. M. Keck Center for Behavioral Biology, Campus Box 7613, North Carolina State University, Raleigh, NC 27695-7613, USA zcdevrie@ncsu.edu.
[Ti] Título:Feel the heat: activation, orientation and feeding responses of bed bugs to targets at different temperatures.
[So] Source:J Exp Biol;219(Pt 23):3773-3780, 2016 Dec 01.
[Is] ISSN:1477-9145
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Host location in bed bugs is poorly understood. Of the primary host-associated cues known to attract bed bugs - CO , odors, heat - heat has received little attention as an independent stimulus. We evaluated the effects of target temperatures ranging from 23 to 48°C on bed bug activation, orientation and feeding. Activation and orientation responses were assessed using a heated target in a circular arena. All targets heated above ambient temperature activated bed bugs (initiated movement) and elicited oriented movement toward the target, with higher temperatures generally resulting in faster activation and orientation. The distance over which bed bugs could orient toward a heat source was measured using a 2-choice T-maze assay. Positive thermotaxis was limited to distances <3 cm. Bed bug feeding responses on an artificial feeding system increased with feeder temperature up to 38 and 43°C, and declined precipitously at 48°C. In addition, bed bugs responded to the relative difference between ambient and feeder temperatures. These results highlight the wide range of temperatures that elicit activation, orientation and feeding responses in bed bugs. In contrast, the ability of bed bugs to correctly orient towards a heated target, independently of other cues, is limited to very short distances (<3 cm). Finally, bed bug feeding is shown to be relative to ambient temperature, not an absolute response to feeder blood temperature.
[Mh] Termos MeSH primário: Percevejos-de-Cama/fisiologia
Comportamento Alimentar/fisiologia
Temperatura Alta
Atividade Motora/fisiologia
Resposta Táctica/fisiologia
[Mh] Termos MeSH secundário: Animais
Orientação Espacial
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170803
[Lr] Data última revisão:
170803
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161001
[St] Status:MEDLINE


  10 / 20 MEDLINE  
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[PMID]:27612295
[Au] Autor:Muñoz MM; Langham GM; Brandley MC; Rosauer DF; Williams SE; Moritz C
[Ad] Endereço:Department of Biology, Duke University, Durham, North Carolina, 27708. mmm109@duke.edu.
[Ti] Título:Basking behavior predicts the evolution of heat tolerance in Australian rainforest lizards.
[So] Source:Evolution;70(11):2537-2549, 2016 Nov.
[Is] ISSN:1558-5646
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:There is pressing urgency to understand how tropical ectotherms can behaviorally and physiologically respond to climate warming. We examine how basking behavior and thermal environment interact to influence evolutionary variation in thermal physiology of multiple species of lygosomine rainforest skinks from the Wet Tropics of northeastern Queensland, Australia (AWT). These tropical lizards are behaviorally specialized to exploit canopy or sun, and are distributed across marked thermal clines in the AWT. Using phylogenetic analyses, we demonstrate that physiological parameters are either associated with changes in local thermal habitat or to basking behavior, but not both. Cold tolerance, the optimal sprint speed, and performance breadth are primarily influenced by local thermal environment. Specifically, montane lizards are more cool tolerant, have broader performance breadths, and higher optimum sprinting temperatures than their lowland counterparts. Heat tolerance, in contrast, is strongly affected by basking behavior: there are two evolutionary optima, with basking species having considerably higher heat tolerance than shade skinks, with no effect of elevation. These distinct responses among traits indicate the multiple selective pressures and constraints that shape the evolution of thermal performance. We discuss how behavior and physiology interact to shape organisms' vulnerability and potential resilience to climate change.
[Mh] Termos MeSH primário: Aclimatação
Evolução Molecular
Temperatura Alta
Lagartos/genética
Resposta Táctica
[Mh] Termos MeSH secundário: Animais
Austrália
Lagartos/fisiologia
Locomoção
Floresta Úmida
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170630
[Lr] Data última revisão:
170630
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160910
[St] Status:MEDLINE
[do] DOI:10.1111/evo.13064



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