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[PMID]:28452690
[Au] Autor:Prior KN; Bond MJ
[Ad] Endereço:School of Medicine, Flinders University, Adelaide, Australia.
[Ti] Título:Patterns of 'Abnormal' Illness Behavior among Healthy Individuals.
[So] Source:Am J Health Behav;41(2):139-146, 2017 Mar 01.
[Is] ISSN:1945-7359
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: We extend the seminal work of Professor Issy Pilowsky by presenting a contemporary re-conceptualization of abnormal illness behavior (AIB) as a general psychological phenomenon evident among healthy community members. METHODS: Participants (N = 344) completed a self- report questionnaire comprising health information and well-validated psychological measures from the field of somatization (eg, AIB, attributional style for physical symptoms, cognitive distortion of somatic information, illness likelihood, maladaptive coping). RESULTS: Cluster analysis of illness behavior responses resulted in 3 unique groupings distinguished by key health and psychological variables. Cluster 1 reflected 'normal' responses, Cluster 2 'atypical' and Cluster 3 'maladaptive'. Cluster 3 may represent a personality attribute indicative of a general style of interpreting illness in a more extreme way (trait AIB) whereas Cluster 2 may reflect a transient response to a specific illness event (state AIB). CONCLUSIONS: The construct of 'abnormal' illness behavior may usefully be extended to include individual differences in responses regardless of current health status. Furthermore, the potential to further characterize illness behavior as either dispositional (trait) or situational (state) emerges as a fruitful area for future analyses. Specifically, longitudinal studies are recommended to determine the causal links between health events and illness behavior profiles.
[Mh] Termos MeSH primário: Comportamento de Doença/classificação
Personalidade/classificação
Transtornos Somatoformes/classificação
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Idoso de 80 Anos ou mais
Análise por Conglomerados
Feminino
Seres Humanos
Masculino
Meia-Idade
Transtornos Somatoformes/fisiopatologia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180306
[Lr] Data última revisão:
180306
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170429
[St] Status:MEDLINE
[do] DOI:10.5993/AJHB.41.2.4


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[PMID]:29351316
[Au] Autor:Yeh CH; Hsieh LP; Lin MC; Wei TS; Lin HC; Chang CC; Hsing CH
[Ad] Endereço:Department of Medicinal Botanicals and Health applications, Da-Yeh University, Changhua, Taiwan.
[Ti] Título:Dexmedetomidine reduces lipopolysaccharide induced neuroinflammation, sickness behavior, and anhedonia.
[So] Source:PLoS One;13(1):e0191070, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Peripheral innate immune response may induce sickness behavior through activating microglia, excessive cytokines production, and neuroinflammation. Dexmedetomidine (Dex) has anti-inflammatory effect. We investigated the effects of Dex on lipopolysaccharide (LPS)-induced neuroinflammation and sickness behavior in mice. MATERIALS AND METHODS: BALB/c mice were intraperitoneally (i.p.) injected with Dex (50 ug/kg) or vehicle. One hour later, the mice were injected (i.p.) with Escherichia coli LPS (0.33 mg/kg) or saline (n = 6 in each group). We analyzed the food and water intake, body weight loss, and sucrose preference of the mice for 24h. We also determined microglia activation and cytokines expression in the brains of the mice. In vitro, we determine cytokines expression in LPS-treated BV-2 microglial cells with or without Dex treatment. RESULTS: In the Dex-pretreated mice, LPS-induced sickness behavior (anorexia, weight loss, and social withdrawal) were attenuated and microglial activation was lower than vehicle control. The mRNA expression of TNF-α, MCP-1, indoleamine 2, 3 dioxygenase (IDO), caspase-3, and iNOS were increased in the brain of LPS-challenged mice, which were reduced by Dex but not vehicle. CONCLUSION: Dexmedetomidine diminished LPS-induced neuroinflammation in the mouse brain and modulated the cytokine-associated changes in sickness behavior.
[Mh] Termos MeSH primário: Anedonia/efeitos dos fármacos
Encéfalo/efeitos dos fármacos
Dexmedetomidina/farmacologia
Comportamento de Doença/efeitos dos fármacos
Inflamação/induzido quimicamente
Lipopolissacarídeos/toxicidade
[Mh] Termos MeSH secundário: Animais
Apoptose/efeitos dos fármacos
Encéfalo/patologia
Inflamação/patologia
Masculino
Camundongos
Camundongos Endogâmicos BALB C
Microglia/efeitos dos fármacos
Reação em Cadeia da Polimerase em Tempo Real
Reação em Cadeia da Polimerase Via Transcriptase Reversa
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Lipopolysaccharides); 67VB76HONO (Dexmedetomidine)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180221
[Lr] Data última revisão:
180221
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180120
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0191070


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[PMID]:28958089
[Au] Autor:Stites SD; Karlawish J; Harkins K; Rubright JD; Wolk D
[Ad] Endereço:Department of Medical Ethics and Health Policy, Perlman School of Medicine.
[Ti] Título:Awareness of Mild Cognitive Impairment and Mild Alzheimer's Disease Dementia Diagnoses Associated With Lower Self-Ratings of Quality of Life in Older Adults.
[So] Source:J Gerontol B Psychol Sci Soc Sci;72(6):974-985, 2017 Oct 01.
[Is] ISSN:1758-5368
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Objective: This study examined how awareness of diagnostic label impacted self-reported quality of life (QOL) in persons with varying degrees of cognitive impairment. Method: Older adults (n = 259) with normal cognition, Mild Cognitive Impairment (MCI), or mild Alzheimer's disease dementia (AD) completed tests of cognition and self-report questionnaires that assessed diagnosis awareness and multiple domains of QOL: cognitive problems, activities of daily living, physical functioning, mental wellbeing, and perceptions of one's daily life. We compared measures of QOL by cognitive performance, diagnosis awareness, and diagnostic group. Results: Persons with MCI or AD who were aware of their diagnosis reported lower average satisfaction with daily life (QOL-AD), basic functioning (BADL Scale), and physical wellbeing (SF-12 PCS), and more difficulties in daily life (DEM-QOL) than those who were unaware (all p ≤ .007). Controlling for gender, those expecting their condition to worsen over time reported greater depression (GDS), higher stress (PSS), lower quality of daily life (QOL-AD, DEM-QOL), and more cognitive difficulties (CDS) compared to others (all p < .05). Discussion: Persons aware of their diagnostic label-either MCI or AD-and its prognosis report lower QOL than those unaware of these facts about themselves. These relationships are independent of the severity of cognitive impairment.
[Mh] Termos MeSH primário: Doença de Alzheimer/psicologia
Conscientização
Disfunção Cognitiva/psicologia
Qualidade de Vida/psicologia
[Mh] Termos MeSH secundário: Atividades Cotidianas/classificação
Atividades Cotidianas/psicologia
Idoso
Idoso de 80 Anos ou mais
Doença de Alzheimer/diagnóstico
Disfunção Cognitiva/diagnóstico
Estudos de Coortes
Transtorno Depressivo/diagnóstico
Transtorno Depressivo/psicologia
Feminino
Seres Humanos
Comportamento de Doença
Entrevista Psicológica
Estudos Longitudinais
Masculino
Testes Neuropsicológicos/estatística & dados numéricos
Psicometria
Fatores de Risco
Estresse Psicológico/diagnóstico
Estresse Psicológico/psicologia
Inquéritos e Questionários
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171104
[Lr] Data última revisão:
171104
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170929
[St] Status:MEDLINE
[do] DOI:10.1093/geronb/gbx100


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[PMID]:28806788
[Au] Autor:Wang N; Ma H; Li Z; Gao Y; Cao X; Jiang Y; Zhou Y; Liu S
[Ad] Endereço:Department of Anesthesiology, The First Hospital of China Medical University, Shenyang, Liaoning, China.
[Ti] Título:Chronic unpredictable stress exacerbates surgery-induced sickness behavior and neuroinflammatory responses via glucocorticoids secretion in adult rats.
[So] Source:PLoS One;12(8):e0183077, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:METHODS: Sprague-Dawley adult male rats (12-14 weeks old) were exposed to 14-day CUS and then subjected to partial hepatectomy 24 h after the last stress session. The rats were pretreated with an antagonist of the glucocorticoids (GCs) receptor RU486 (30 mg/kg, i.p.) 1 h prior to stress exposure. The behavioral changes were evaluated with open field test and elevated plus-maze test. The hippocampal cytokines interleukin (IL)-1ß and IL-6 were measured on postoperative days 1, 3 and 7. Ionized calcium binding adaptor protein (Iba)-1, microglial M2 phenotype marker Arg1, brain derived neurotrophic factor (BDNF) and CD200 were also examined at each time point. RESULTS: CUS exacerbated surgery-induced sickness behavior. Exposure to CUS alone failed to alter the levels of pro-inflammatory cytokines in the brain. However, CUS exaggerated surgery-induced pro-inflammatory cytokines expression (e.g. IL-1ß and IL-6) and upregulated the levels of Iba-1 on postoperative days 1 and 3. An additional significant decreased BDNF, CD200 and a lower level of Arg1 were also observed in the stressed rats following surgical procedure. Pretreatment with RU486 blunted the potentiating effects of CUS on surgery-induced sickness behavior and neuroinflammatory responses. CONCLUSION: Chronic unpredictable stress enhanced surgery-induced sickness behavior and neuroinflammatory responses. Stress-induced GCs played a pivotal role in enhancing surgery-induced neuroinflammatory processes by modulation of microglia functions.
[Mh] Termos MeSH primário: Glucocorticoides/secreção
Hepatectomia/efeitos adversos
Comportamento de Doença
Inflamação/complicações
Neurônios/patologia
Estresse Psicológico/complicações
[Mh] Termos MeSH secundário: Animais
Antígenos CD/genética
Antígenos CD/metabolismo
Ansiedade/sangue
Ansiedade/complicações
Ansiedade/fisiopatologia
Arginase/metabolismo
Biomarcadores/metabolismo
Peso Corporal
Proteínas de Ligação ao Cálcio/metabolismo
Doença Crônica
Glucocorticoides/sangue
Hipocampo/patologia
Hipocampo/fisiopatologia
Inflamação/sangue
Inflamação/patologia
Inflamação/fisiopatologia
Interleucina-6/metabolismo
Masculino
Proteínas dos Microfilamentos/metabolismo
Microglia/metabolismo
Atividade Motora
Fenótipo
RNA Mensageiro/genética
RNA Mensageiro/metabolismo
Ratos Sprague-Dawley
Estresse Psicológico/sangue
Estresse Psicológico/fisiopatologia
Regulação para Cima
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Aif1 protein, rat); 0 (Antigens, CD); 0 (Biomarkers); 0 (Calcium-Binding Proteins); 0 (Glucocorticoids); 0 (Interleukin-6); 0 (Microfilament Proteins); 0 (RNA, Messenger); 0 (antigens, CD200); EC 3.5.3.1 (Arginase)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171009
[Lr] Data última revisão:
171009
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170815
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0183077


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[PMID]:28806206
[Au] Autor:Walters JL; Baxter K; Chapman H; Jackson T; Sethuramachandran A; Couldridge M; Joshi HR; Kundra P; Liu X; Nair D; Sullivan B; Shotwell MS; Jense RJ; Kassebaum NJ; McQueen KAK
[Ad] Endereço:From the *Department of Anesthesiology and Pain Medicine, Vanderbilt University, Nashville, Tennessee; †University of Washington School of Medicine, Seattle, Washington; ‡Department of Anaesthesiology and Critical Care, Jawaharlal Institute of Postgraduate Medical Education and Research, Institute of National Importance, Pondicherry, India; §Casper, Wyoming; ∥Nepal Medical College, Kathmandu, Nepal; ¶Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, Tennessee; #Department of Preventive and Social Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Institute of National Importance, Pondicherry, India; **Behavioral Neuroscience Program, Western Washington University, Bellingham, Washington; ††Department of Anesthesiology and Pain Medicine and Global Health Adjunct, University of Washington, Seattle, Washington; ‡‡Department of Pediatric Anesthesiology and Pain Medicine, Seattle Children's Hospital, Seattle, Washington; §§Institute for Health Metrics and Evaluation, University of Washington, Seattle, Washington; and ∥∥Department of Anesthesiology, Director of Vanderbilt Anesthesia Global Health and Development Affiliate Faculty, Vanderbilt Institute for Global Health, Vanderbilt University Medical Center, Nashville, Tennessee.
[Ti] Título:Chronic Pain and Associated Factors in India and Nepal: A Pilot Study of the Vanderbilt Global Pain Survey.
[So] Source:Anesth Analg;125(5):1616-1626, 2017 Nov.
[Is] ISSN:1526-7598
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Evaluation and treatment of chronic pain worldwide are limited by the lack of standardized assessment tools incorporating consistent definitions of pain chronicity and specific queries of known social and psychological risk factors for chronic pain. The Vanderbilt Global Pain Survey (VGPS) was developed as a tool to address these concerns, specifically in the low- and middle-income countries where global burden is highest. METHODS: The VGPS was developed using standardized and cross-culturally validated metrics, including the Brief Pain Inventory and World Health Organization Disability Assessment Scale, as well as the Pain Catastrophizing Scale, the Fibromyalgia Survey Questionnaire along with queries about pain attitudes to assess the prevalence of chronic pain and disability along with its psychosocial and emotional associations. The VGPS was piloted in both Nepal and India over a 1-month period in 2014, allowing for evaluation of this tool in 2 distinctly diverse cultures. RESULTS: Prevalence of chronic pain in Nepal and India was consistent with published data. The Nepali cohort displayed a pain point prevalence of 48%-50% along with some form of disability present in approximately one third of the past 30 days. Additionally, 11% of Nepalis recorded pain in 2 somatic sites and 39% of those surveyed documented a history of a traumatic event. In the Indian cohort, pain point prevalence was approximately 24% to 41% based on the question phrasing, and any form of disability was present in 6 of the last 30 days. Of the Indians surveyed, 11% reported pain in 2 somatic sites, with only 4% reporting a previous traumatic event. Overall, Nepal had significantly higher chronic pain prevalence, symptom severity, widespread pain, and self-reported previous traumatic events, yet lower reported pain severity. CONCLUSIONS: Our findings confirm prevalent chronic pain, while revealing pertinent cultural differences and survey limitations that will inform future assessment strategies. Specific areas for improvement identified in this VGPS pilot study included survey translation methodology, redundancy of embedded metrics and cultural limitations in representative sampling and in detecting the prevalence of mental health illness, catastrophizing behavior, and previous traumatic events. International expert consensus is needed.
[Mh] Termos MeSH primário: Dor Crônica/epidemiologia
[Mh] Termos MeSH secundário: Atividades Cotidianas
Adulto
Sensibilização do Sistema Nervoso Central
Dor Crônica/diagnóstico
Dor Crônica/fisiopatologia
Dor Crônica/psicologia
Efeitos Psicossociais da Doença
Características Culturais
Avaliação da Deficiência
Feminino
Conhecimentos, Atitudes e Prática em Saúde
Nível de Saúde
Inquéritos Epidemiológicos
Seres Humanos
Comportamento de Doença
Índia/epidemiologia
Masculino
Meia-Idade
Nepal/epidemiologia
Medição da Dor
Percepção da Dor
Projetos Piloto
Prevalência
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171030
[Lr] Data última revisão:
171030
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170815
[St] Status:MEDLINE
[do] DOI:10.1213/ANE.0000000000002360


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[PMID]:28800835
[Au] Autor:Wilson C; Corrigan R; Braun L
[Ad] Endereço:Acupuncture and Integrative Medicine Center, Malcolm Grow Medical Clinics and Surgery Center, Joint Base Andrews, MD. Electronic address: candy.wilson@usuhs.edu.
[Ti] Título:Deployed women's illness behaviors while managing genitourinary symptoms: An exploratory theoretical synthesis of two qualitative studies.
[So] Source:Nurs Outlook;65(5S):S17-S25, 2017 Sep - Oct.
[Is] ISSN:1528-3968
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The recent removal of United States military combat exclusion rules resulted in more women serving in forward deployed austere conditions. In the deployed setting, women were diagnosed with genitourinary (GU) conditions five times greater than men. PURPOSE: Describe deployed military women's GU illness behaviors. METHOD: Two qualitative descriptive studies interviewing military women and enlisted medics were synthesized using the Illness Behavior Model. DISCUSSION: Similar and divergent views on the impact of the military culture of the illness behaviors were described by women and medics. Both agreed appropriate attention on managing GU symptoms must continue; however differing strategies were appraised. One agreed option was to offer a health care mentor. CONCLUSION: The Illness Behavior Model provided an excellent framework for evaluation of military women's illness behaviors exposing areas for comparing and contrasting the perspectives provided. While significant changes have been made, additional strategies will continue to improve the women's deployed health care quality.
[Mh] Termos MeSH primário: Doenças Urogenitais Femininas/psicologia
Comportamento de Doença
Militares
[Mh] Termos MeSH secundário: Adaptação Psicológica
Adulto
Feminino
Doenças Urogenitais Femininas/complicações
Doenças Urogenitais Femininas/terapia
Seres Humanos
Modelos Teóricos
Aceitação pelo Paciente de Cuidados de Saúde
Pesquisa Qualitativa
Autocuidado
Estados Unidos
Exposição à Guerra
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171113
[Lr] Data última revisão:
171113
[Sb] Subgrupo de revista:AIM; IM; N
[Da] Data de entrada para processamento:170813
[St] Status:MEDLINE


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[PMID]:28601279
[Au] Autor:Avitsur R; Paley S; Franko M; Wolff N; Eyal N; Doron R
[Ad] Endereço:School of Behavioral Sciences, The Academic College of Tel Aviv-Yaffo, Tel Aviv, Israel. Electronic address: avitsur@mta.ac.il.
[Ti] Título:Escitalopram or novel herbal treatments differentially alter cytokine and behavioral responses to immune challenge.
[So] Source:J Neuroimmunol;309:111-118, 2017 Aug 15.
[Is] ISSN:1872-8421
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Studies suggest that inflammation is involved in the pathophysiology of depression. The present study examined the effects of the commonly used antidepressant escitalopram, in comparison with a novel herbal treatment (NHT) consisted of Crataegus pinnatifida, Triticum aestivum, Lilium brownii and Fructus Ziziphus jujuba, on cytokine and behavioral responses to an immune challenge. Escitalopram augmented lipopolysaccharide-induced tumor necrosis factor (TNF)-α peripheral secretion and induced a faster kinetics of interleukin-1ß secretion, while marginally reducing sickness behavior. NHT, on the other hand, completely abolished lipopolysaccharide-induced interleukin-1ß and TNFα peripheral secretion and diminished sickness behavior. These findings may have implications for the treatment of depressive symptoms associated with immune activation.
[Mh] Termos MeSH primário: Citalopram/uso terapêutico
Citocinas/imunologia
Citocinas/metabolismo
Comportamento de Doença/efeitos dos fármacos
Lipopolissacarídeos/toxicidade
Preparações de Plantas/uso terapêutico
[Mh] Termos MeSH secundário: Animais
Antidepressivos de Segunda Geração/farmacologia
Antidepressivos de Segunda Geração/uso terapêutico
Citalopram/farmacologia
Depressão/tratamento farmacológico
Depressão/imunologia
Depressão/metabolismo
Comportamento de Doença/fisiologia
Masculino
Camundongos
Preparações de Plantas/farmacologia
Resultado do Tratamento
Fator de Necrose Tumoral alfa/imunologia
Fator de Necrose Tumoral alfa/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antidepressive Agents, Second-Generation); 0 (Cytokines); 0 (Lipopolysaccharides); 0 (Plant Preparations); 0 (Tumor Necrosis Factor-alpha); 0DHU5B8D6V (Citalopram)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170821
[Lr] Data última revisão:
170821
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170612
[St] Status:MEDLINE


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[PMID]:28581479
[Au] Autor:Campos CA; Bowen AJ; Han S; Wisse BE; Palmiter RD; Schwartz MW
[Ad] Endereço:Department of Biochemistry, Howard Hughes Medical Institute, University of Washington, Seattle, Washington, USA.
[Ti] Título:Cancer-induced anorexia and malaise are mediated by CGRP neurons in the parabrachial nucleus.
[So] Source:Nat Neurosci;20(7):934-942, 2017 Jul.
[Is] ISSN:1546-1726
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Anorexia is a common manifestation of chronic diseases, including cancer. Here we investigate the contribution to cancer anorexia made by calcitonin gene-related peptide (CGRP) neurons in the parabrachial nucleus (PBN) that transmit anorexic signals. We show that CGRP neurons are activated in mice implanted with Lewis lung carcinoma cells. Inactivation of CGRP neurons before tumor implantation prevents anorexia and loss of lean mass, and their inhibition after symptom onset reverses anorexia. CGRP neurons are also activated in Apc mice, which develop intestinal cancer and lose weight despite the absence of reduced food intake. Inactivation of CGRP neurons in Apc mice permits hyperphagia that counteracts weight loss, revealing a role for these neurons in a 'nonanorexic' cancer model. We also demonstrate that inactivation of CGRP neurons prevents lethargy, anxiety and malaise associated with cancer. These findings establish CGRP neurons as key mediators of cancer-induced appetite suppression and associated behavioral changes.
[Mh] Termos MeSH primário: Anorexia/fisiopatologia
Peptídeo Relacionado com Gene de Calcitonina/fisiologia
Carcinoma Pulmonar de Lewis/fisiopatologia
Comportamento de Doença/fisiologia
Neoplasias/fisiopatologia
Núcleos Parabraquiais/fisiologia
[Mh] Termos MeSH secundário: Proteína da Polipose Adenomatosa do Colo/genética
Animais
Comportamento Animal/fisiologia
Peso Corporal
Caquexia/fisiopatologia
Peptídeo Relacionado com Gene de Calcitonina/antagonistas & inibidores
Peptídeo Relacionado com Gene de Calcitonina/genética
Clozapina/análogos & derivados
Clozapina/farmacologia
Metabolismo Energético/fisiologia
Feminino
Masculino
Metaloendopeptidases/farmacologia
Camundongos
Camundongos Transgênicos
Núcleos Parabraquiais/efeitos dos fármacos
Toxina Tetânica/farmacologia
Células Tumorais Cultivadas/transplante
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Adenomatous Polyposis Coli Protein); 0 (Calca protein, mouse); 0 (Tetanus Toxin); 0 (adenomatous polyposis coli protein, mouse); 83652-28-2 (Calcitonin Gene-Related Peptide); EC 3.4.24.- (Metalloendopeptidases); EC 3.4.24.- (zinc-endopeptidase, tetanus neurotoxin); J60AR2IKIC (Clozapine); MZA8BK588J (clozapine N-oxide)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170606
[St] Status:MEDLINE
[do] DOI:10.1038/nn.4574


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[PMID]:28488534
[Au] Autor:Wertli MM; Steurer J
[Ad] Endereço:1 Horten-Zentrum für praxisorientierte Forschung und Wissenstransfer, Universität Zürich, Universitätsspital Zürich.
[Ti] Título:Bedeutung prognostischer Faktoren bei unspezifischen, lumbalen Rückenschmerzen..
[So] Source:Praxis (Bern 1994);106(10):527-531, 2017.
[Is] ISSN:1661-8157
[Cp] País de publicação:Switzerland
[La] Idioma:ger
[Mh] Termos MeSH primário: Dor Lombar/diagnóstico
Dor Lombar/etiologia
[Mh] Termos MeSH secundário: Adaptação Psicológica
Medo
Seres Humanos
Comportamento de Doença
Dor Lombar/psicologia
Dor Lombar/terapia
Modelos Psicológicos
Prognóstico
Procedimentos Desnecessários
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170707
[Lr] Data última revisão:
170707
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170511
[St] Status:MEDLINE
[do] DOI:10.1024/1661-8157/a002677


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[PMID]:28392040
[Au] Autor:Sethares KA; Asselin ME
[Ad] Endereço:Adult Nursing Department, University of Massachusetts Dartmouth, North Dartmouth, MA, USA. Electronic address: ksethares@umassd.edu.
[Ti] Título:The effect of guided reflection on heart failure self-care maintenance and management: A mixed methods study.
[So] Source:Heart Lung;46(3):192-198, 2017 May - Jun.
[Is] ISSN:1527-3288
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: Evaluate the effect of structured, guided reflection on patient descriptions of self-care maintenance and management. BACKGROUND: Inadequate HF self-care behaviors are linked to hospitalizations. Symptom monitoring and recognition are precursors to adequate HF self-care. Reflection on actions taken during HF exacerbations may lead to insights and future changes in HF self-care maintenance and management. METHODS: One-group mixed method pre-test/post-test design. Following cognitive screening, self-care maintenance and management was measured prior to the intervention at a home visit one-week after hospital discharge, and one-month post intervention. Qualitative data consisted of audiotaped individual interviews with participants, field notes and reflective diaries kept by patients. RESULTS: The results (N = 10) demonstrate large effect sizes and increases in self-care maintenance (69.9 vs 79.6, d = 1.04) and management (47.2 vs 63.9, d = 2.53) scores after intervention. Eight themes emerged from the data that reflected the HF participant's experience of self-care. Reflection evoked emotions around concerns for family and mortality. Participants linked symptoms experienced with contextual factors which facilitated discussion about changing future actions. CONCLUSIONS: Purposeful reflection may be necessary for the development of self-care. Guided reflection on previous actions that includes contextual considerations may also play a role in enhancing self-care management by allowing the person to more fully understand the illness experience.
[Mh] Termos MeSH primário: Insuficiência Cardíaca/psicologia
Comportamento de Doença
Autocuidado/métodos
[Mh] Termos MeSH secundário: Idoso
Feminino
Insuficiência Cardíaca/terapia
Hospitalização/tendências
Seres Humanos
Assistência de Longa Duração/métodos
Masculino
Qualidade de Vida
Inquéritos e Questionários
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170929
[Lr] Data última revisão:
170929
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170411
[St] Status:MEDLINE



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