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[PMID]:29364944
[Au] Autor:Noyes N; Cho KC; Ravel J; Forney LJ; Abdo Z
[Ad] Endereço:Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, United States of America.
[Ti] Título:Associations between sexual habits, menstrual hygiene practices, demographics and the vaginal microbiome as revealed by Bayesian network analysis.
[So] Source:PLoS One;13(1):e0191625, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The vaginal microbiome plays an influential role in several disease states in reproductive age women, including bacterial vaginosis (BV). While demographic characteristics are associated with differences in vaginal microbiome community structure, little is known about the influence of sexual and hygiene habits. Furthermore, associations between the vaginal microbiome and risk symptoms of bacterial vaginosis have not been fully elucidated. Using Bayesian network (BN) analysis of 16S rRNA gene sequence results, demographic and extensive questionnaire data, we describe both novel and previously documented associations between habits of women and their vaginal microbiome. The BN analysis approach shows promise in uncovering complex associations between disparate data types. Our findings based on this approach support published associations between specific microbiome members (e.g., Eggerthella, Gardnerella, Dialister, Sneathia and Ruminococcaceae), the Nugent score (a BV diagnostic) and vaginal pH (a risk symptom of BV). Additionally, we found that several microbiome members were directly connected to other risk symptoms of BV (such as vaginal discharge, odor, itch, irritation, and yeast infection) including L. jensenii, Corynebacteria, and Proteobacteria. No direct connections were found between the Nugent Score and risk symptoms of BV other than pH, indicating that the Nugent Score may not be the most useful criteria for assessment of clinical BV. We also found that demographics (i.e., age, ethnicity, previous pregnancy) were associated with the presence/absence of specific vaginal microbes. The resulting BN revealed several as-yet undocumented associations between birth control usage, menstrual hygiene practices and specific microbiome members. Many of these complex relationships were not identified using common analytical methods, i.e., ordination and PERMANOVA. While these associations require confirmatory follow-up study, our findings strongly suggest that future studies of the vaginal microbiome and vaginal pathologies should include detailed surveys of participants' sanitary, sexual and birth control habits, as these can act as confounders in the relationship between the microbiome and disease. Although the BN approach is powerful in revealing complex associations within multidimensional datasets, the need in some cases to discretize the data for use in BN analysis can result in loss of information. Future research is required to alleviate such limitations in constructing BN networks. Large sample sizes are also required in order to allow for the incorporation of a large number of variables (nodes) into the BN, particularly when studying associations between metadata and the microbiome. We believe that this approach is of great value, complementing other methods, to further our understanding of complex associations characteristic of microbiome research.
[Mh] Termos MeSH primário: Higiene
Menstruação
Microbiota
Comportamento Sexual
Vagina/microbiologia
[Mh] Termos MeSH secundário: Teorema de Bayes
Feminino
Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180125
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0191625


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[PMID]:28467238
[Au] Autor:Charlton BM; Reisner SL; Agénor M; Gordon AR; Sarda V; Austin SB
[Ad] Endereço:1 Division of Adolescent/Young Adult Medicine, Boston Children's Hospital , Boston, Massachusetts.
[Ti] Título:Sexual Orientation Disparities in Human Papillomavirus Vaccination in a Longitudinal Cohort of U.S. Males and Females.
[So] Source:LGBT Health;4(3):202-209, 2017 Jun.
[Is] ISSN:2325-8306
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PURPOSE: This study sought to examine how human papillomavirus (HPV) vaccination may differ across sexual orientation groups (e.g., bisexuals compared to heterosexuals)-particularly in boys and men, about whom little is known. METHODS: Data were from a prospective cohort of 10,663 U.S. females and males enrolled in the Growing Up Today Study followed from 1996 to 2014. Participants were aged 11-24 years when the vaccine was approved for females in 2006 and 14-27 years when approved for males in 2009. In addition to reporting sexual orientation identity/attractions, participants reported sex of lifetime sexual partners. Log-binominal models were used to examine HPV vaccination across sexual orientation groups. RESULTS: Among females, 56% received ≥1 dose. In contrast, 8% of males obtained ≥1 dose; HPV vaccination initiation was especially low among completely heterosexual males. After adjusting for potential confounders, completely heterosexual (risk ratio [RR]; 95% confidence interval [CI]: 0.45 [0.30-0.68]) and mostly heterosexual (RR; 95% CI: 0.44 [0.25-0.78]) males were half as likely to have received even a single dose compared to gay males. Compared to lesbians, no differences were observed for completely heterosexual or bisexual females, but mostly heterosexual females were 20% more likely to have received at least one dose. CONCLUSIONS: HPV vaccination rates in the U.S. are strikingly low and special attention is needed for boys and men, especially those who do not identify as gay. Vaccinating everyone, regardless of sex/gender and/or sexual orientation, will not only lower that individual's susceptibility but also decrease transmission to partners, females and/or males, to help eradicate HPV through herd immunity.
[Mh] Termos MeSH primário: Disparidades em Assistência à Saúde
Vacinas contra Papillomavirus/uso terapêutico
Comportamento Sexual
Minorias Sexuais e de Gênero
[Mh] Termos MeSH secundário: Adolescente
Criança
Feminino
Seres Humanos
Estudos Longitudinais
Masculino
Infecções por Papillomavirus/epidemiologia
Infecções por Papillomavirus/prevenção & controle
Estudos Prospectivos
Estados Unidos
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Papillomavirus Vaccines)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170504
[St] Status:MEDLINE
[do] DOI:10.1089/lgbt.2016.0103


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[PMID]:28453387
[Au] Autor:Cahill SR; Makadon HJ
[Ad] Endereço:1 Health Policy Research, The Fenway Institute , Fenway Health, Boston, Massachusetts.
[Ti] Título:If They Don't Count Us, We Don't Count: Trump Administration Rolls Back Sexual Orientation and Gender Identity Data Collection.
[So] Source:LGBT Health;4(3):171-173, 2017 Jun.
[Is] ISSN:2325-8306
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The Trump Administration recently removed sexual orientation and gender identity (SOGI) questions from a national aging survey, and decided not to add a sexual orientation category and a transgender identity field to a national disability survey as planned. These actions have raised concerns that the major expansion of SOGI data collection on surveys and in clinical settings, which has occurred in recent years, may be under threat. SOGI data collection is essential to understand lesbian, gay, bisexual, and transgender (LGBT) health and the extent to which LGBT people access critical social services, including elder and disability services essential for living in community.
[Mh] Termos MeSH primário: Coleta de Dados
Identidade de Gênero
Comportamento Sexual
Minorias Sexuais e de Gênero/estatística & dados numéricos
[Mh] Termos MeSH secundário: Envelhecimento
Coleta de Dados/legislação & jurisprudência
Seres Humanos
Inquéritos e Questionários
Estados Unidos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170429
[St] Status:MEDLINE
[do] DOI:10.1089/lgbt.2017.0073


  4 / 47175 MEDLINE  
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[PMID]:28742430
[Au] Autor:Andac T; Aslan E
[Ad] Endereço:a Kemal Haciyüzbasioglu Aile Sagligi Merkezi Kartal , Istanbul , Turkey.
[Ti] Título:Sexual life of women in the climacterium: A community-based study.
[So] Source:Health Care Women Int;38(12):1344-1355, 2017 Dec.
[Is] ISSN:1096-4665
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Our purpose of conducting this community-based study was to determine sexual functions of women in climacterium and effects of menopausal symptoms on sexual functions. It was descriptive, cross-sectional, and community-based. The study sample consisted of 282 climacteric women. Menopause Rating Scale (MRS), Female Sexual Function Index (FSFI), and Sexual Satisfaction Scale for Women (SSS-W) were used for data collection. The total score was 13.42 ± 8.82 for MRS, 18.73 ± 9.79 for FSFI, and 82.56 ± 18.07 for SSS-W. Seventy-nine-point four percent of the women had sexual dysfunction. While complaints typical of the climacteric period increased, sexual functions and satisfaction decreased.
[Mh] Termos MeSH primário: Climatério
Menopausa
Satisfação Pessoal
Comportamento Sexual/fisiologia
[Mh] Termos MeSH secundário: Idoso
Climatério/fisiologia
Climatério/psicologia
Estudos Transversais
Feminino
Seres Humanos
Menopausa/fisiologia
Menopausa/psicologia
Meia-Idade
Qualidade de Vida
Disfunções Sexuais Fisiológicas/epidemiologia
Disfunções Sexuais Psicogênicas
Fatores Socioeconômicos
Inquéritos e Questionários
Turquia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:N
[Da] Data de entrada para processamento:170726
[St] Status:MEDLINE
[do] DOI:10.1080/07399332.2017.1352588


  5 / 47175 MEDLINE  
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[PMID]:29219248
[Au] Autor:Mackworth-Young CR; Bond V; Wringe A; Konayuma K; Clay S; Chiiya C; Chonta M; Sievwright K; Stangl AL
[Ad] Endereço:Department of Global Health and Development, Faculty of Public Health and Policy, London School of Hygiene and Tropical Medicine, London, United Kingdom.
[Ti] Título:"My mother told me that I should not": a qualitative study exploring the restrictions placed on adolescent girls living with HIV in Zambia.
[So] Source:J Int AIDS Soc;20(4), 2017 Dec.
[Is] ISSN:1758-2652
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: Adolescent girls in sub-Saharan Africa are disproportionately affected by HIV due to a range of social and structural factors. As they transition to adulthood, they are recipients of increasing blame for HIV infection and 'improper' sex, as well as increasing scrutiny, restrictions and surveillance. This study used a qualitative and participatory approach to explore the messaging and restrictions imposed on adolescent girls living with HIV in Zambia. METHODS: Thirty-four in-depth interviews and four participatory workshops were carried out with 24 adolescent girls aged 15 to 19 years old living with HIV in Lusaka, Zambia. Key themes explored included experiences living with HIV, finding out about HIV status, disclosure, experiences with antiretroviral treatment, and support needs. Data were organized, coded and analysed using a grounded theory approach to thematic analysis. This analysis uses data on participants' experiences of living with HIV and their interactions with their parents, guardians and healthcare providers. RESULTS: Family and healthcare providers, partly in a quest to protect both the health of adolescent girls living with HIV and also to protect them from blaming discourse, imposed restrictions on their behaviour around three main topics: don't disclose your HIV status, don't have sex, and don't miss your medicines. These restrictions were often delivered using tactics of fear, and usually disconnected from other options. Participants responded to these messages in several ways, including internalizing the messages, changing their behaviour either to comply with or resist the restrictions, by remaining silent and anxious when restrictions were broken, and developing concerns around their own health and sexual and reproductive aspirations. Participants also sometimes experiencing stigma when restrictions could not be maintained. CONCLUSIONS: Restrictive messages were delivered to adolescent girls living with HIV through the broader social discourses of stigma, religion, and global and local narratives about HIV. Programmes aiming to support adolescent girls living with HIV need to work together with parents and healthcare providers to reflect on the impact of sanctioning messages, and to encourage more enabling and empowering messaging for adolescent girls living with HIV.
[Mh] Termos MeSH primário: Infecções por HIV/psicologia
Responsabilidade Social
Estigma Social
[Mh] Termos MeSH secundário: Adolescente
Atitude Frente à Saúde
Medo
Feminino
Pessoal de Saúde
Seres Humanos
Pesquisa Qualitativa
Religião
Comportamento Sexual
Zâmbia/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180307
[Lr] Data última revisão:
180307
[Sb] Subgrupo de revista:IM; X
[Da] Data de entrada para processamento:171209
[St] Status:MEDLINE
[do] DOI:10.1002/jia2.25035


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[PMID]:29179700
[Au] Autor:Palummieri A; De Carli G; Rosenthal É; Cacoub P; Mussini C; Puro V; PrEPventHIV Italy Study Group
[Ad] Endereço:National Institute for Infectious Diseases "Lazzaro Spallanzani" IRCCS, Department of Epidemiology, Pre-clinical Research and Advanced Diagnostics, via Portuense, 292, 00149, Roma, Italy.
[Ti] Título:Awareness, discussion and non-prescribed use of HIV pre-exposure prophylaxis among persons living with HIV/AIDS in Italy: a Nationwide, cross-sectional study among patients on antiretrovirals and their treating HIV physicians.
[So] Source:BMC Infect Dis;17(1):734, 2017 11 28.
[Is] ISSN:1471-2334
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Before Pre-Exposure Prophylaxis (PrEP) was officially recommended and made available, a few surveys among gay and bisexual men, and persons living with HIV/AIDS (PLWHA), identified an informal use of antiretrovirals (ARVs) for PrEP among HIV-negative individuals. Before PrEP availability in Italy, we aimed to assess whether PLWHA in Italy shared their ARVs with HIV-negative individuals, whether they knew people who were on PrEP, and describe the level of awareness and discussion on this preventive measure among them and people in their close circle. METHODS: Two anonymous questionnaires investigating personal characteristics and PrEP awareness, knowledge, and experience were proposed to HIV specialists and their patients on ARVs in a one-week, cross-sectional survey (December 2013-January 2014). Among PLWHA, a Multivariable Logistic Regression analysis was conducted to identify factors associated with PrEP discussion with peers (close circle and/or HIV associations), and experience (use in close circle and/or personal ARV sharing). RESULTS: Eighty-seven specialists in 31 representative Infectious Diseases departments administered the questionnaire to 1405 PLWHA. Among specialists, 98% reported awareness, 65% knew the dosage schedule, and 14% had previously suggested or prescribed PrEP. Among PLWHA, 45.6% were somehow aware, discussed or had direct or indirect experience of PrEP: 38% "had heard" of PrEP, 24% were aware of studies in HIV-negative individuals demonstrating a risk reduction through the use of ARVs, 22% had discussed PrEP, 12% with peers; 9% reported PrEP use in close circle and 1% personal ARV sharing. Factors predictive of either PrEP discussion with peers or experience differed between men and women, but across all genders were mainly related to having access to information, with HIV association membership being the strongest predictor. CONCLUSIONS: At a time and place where there were neither official information nor proposals or interventions to guide public policies on PrEP in Italy, a significant number of PLWHA were aware of it, and approximately 10% reported PrEP use in their close circle, although they rarely shared their ARVs with uninfected people for this purpose. Official policies and PrEP availability, along with implementation programs, could avoid risks from uncontrolled PrEP procurement and self-administration practices.
[Mh] Termos MeSH primário: Fármacos Anti-HIV/uso terapêutico
Infecções por HIV/prevenção & controle
Conhecimentos, Atitudes e Prática em Saúde
Profilaxia Pré-Exposição/métodos
Comportamento Sexual
[Mh] Termos MeSH secundário: Síndrome de Imunodeficiência Adquirida/tratamento farmacológico
Síndrome de Imunodeficiência Adquirida/prevenção & controle
Adulto
Estudos Transversais
Feminino
Infecções por HIV/tratamento farmacológico
Seres Humanos
Itália
Masculino
Médicos
Automedicação
Minorias Sexuais e de Gênero
Inquéritos e Questionários
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Anti-HIV Agents)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180305
[Lr] Data última revisão:
180305
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171129
[St] Status:MEDLINE
[do] DOI:10.1186/s12879-017-2819-5


  7 / 47175 MEDLINE  
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[PMID]:28457203
[Au] Autor:Kenyon CR
[Ad] Endereço:1 Institute of Tropical Medicine, Antwerp, Belgium.
[Ti] Título:Bypassing the 'rapid-clearance-in-males-buffer': A fourth mechanism to explain how concurrency enhances STI spread.
[So] Source:Int J STD AIDS;28(14):1444-1446, 2017 12.
[Is] ISSN:1758-1052
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:A number of sexually transmitted infections (STIs) persist for a considerably shorter period in the male urethra than the vagina. If the gap between sequential partnerships is longer than the duration of STI colonization in males, then this would protect future female partners from this STI in a setting of serial monogamy. If, however, males have more than one partner at a time (concurrency), then this would enable the STI to bypass this gap/buffer. We therefore propose bypassing the rapid-clearance-in-males-buffer as a fourth mechanism, whereby concurrency could enhance the spread of STIs.
[Mh] Termos MeSH primário: Comportamento Sexual
Parceiros Sexuais
Doenças Sexualmente Transmissíveis/transmissão
[Mh] Termos MeSH secundário: Adulto
Feminino
Seres Humanos
Masculino
Fatores de Tempo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180306
[Lr] Data última revisão:
180306
[Sb] Subgrupo de revista:IM; X
[Da] Data de entrada para processamento:170502
[St] Status:MEDLINE
[do] DOI:10.1177/0956462417706246


  8 / 47175 MEDLINE  
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[PMID]:29343481
[Au] Autor:Ma R; Dixon M
[Ad] Endereço:Department of primary care and public health, School of Public Health, Imperial College London, London UK.
[Ti] Título:Should all patients be asked about their sexual orientation?
[So] Source:BMJ;360:k52, 2018 01 17.
[Is] ISSN:1756-1833
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Comportamento Sexual
[Mh] Termos MeSH secundário: Seres Humanos
Direitos do Paciente
Relações Médico-Paciente
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180301
[Lr] Data última revisão:
180301
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180119
[St] Status:MEDLINE
[do] DOI:10.1136/bmj.k52


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[PMID]:29206976
[Au] Autor:Brotman S; Drummond J; Silverman M; Sussman T; Orzeck P; Barylak L; Wallach I; Billette V
[Ad] Endereço:School of Work, McGill University, 3506 University Street, Montreal, Quebec, Canada.
[Ti] Título:Talking about Sexuality and Intimacy with Women Spousal Caregivers: Perspectives of Service Providers.
[So] Source:Health Soc Work;41(4):263-270, 2016 Nov 20.
[Is] ISSN:0360-7283
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:This article reports the findings of an exploratory study examining service provider perceptions and experiences of addressing sexuality and intimacy with women spousal caregivers. The caregiver-provider encounter is examined, and challenges faced by service providers in addressing sexuality are considered. Themes identified include ambivalence and discomfort, personal and institutional barriers, meanings attributed to sexuality and intimacy, and lack of opportunities to discuss experiences. Strategies to overcome silence and invisibility on the part of service providers in the health and social services system are considered.
[Mh] Termos MeSH primário: Cuidadores/psicologia
Papel Profissional
Sexualidade
Assistentes Sociais
Cônjuges/psicologia
[Mh] Termos MeSH secundário: Adulto
Feminino
Seres Humanos
Entrevistas como Assunto
Masculino
Meia-Idade
Pesquisa Qualitativa
Comportamento Sexual
Parceiros Sexuais
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180227
[Lr] Data última revisão:
180227
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171206
[St] Status:MEDLINE
[do] DOI:10.1093/hsw/hlw040


  10 / 47175 MEDLINE  
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[PMID]:29364938
[Au] Autor:Marti-Pastor M; Perez G; German D; Pont A; Garin O; Alonso J; Gotsens M; Ferrer M
[Ad] Endereço:IMIM (Hospital del Mar Medical Research Institute), Health Services Research Group, Barcelona, Spain.
[Ti] Título:Health-related quality of life inequalities by sexual orientation: Results from the Barcelona Health Interview Survey.
[So] Source:PLoS One;13(1):e0191334, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Studies on health-related quality of life (HRQoL) inequalities according to sexual orientation are scarce. The aim of this study was to assess HRQoL inequalities between lesbian, gay, and bisexual (LGB) people and heterosexuals in the 2011 Barcelona population, to describe the extent to which sociodemographic characteristics, health-related behaviors, and chronic conditions could explain such inequalities, and to understand if they are sexual orientation inequities. METHODS: In the 2011 Barcelona Health Interview Survey 3277 adults answered the EQ-5D, which measures five dimensions of HRQoL summarized into a single utility index (1 = perfect health, 0 = death). To assess HRQoL differences by sexual orientation we constructed Tobit models for the EQ-5D index, and Poisson regression models for the EQ-5D dimensions. In both cases, nested models were constructed to assess the mediator role of selected variables. RESULTS: After adjusting by socio-demographic variables, the LGB group presented a significantly lower EQ-5D index than heterosexuals, and higher prevalence ratios of problems in physical EQ-5D dimensions among both genders: adjusted prevalence ratio (aPR) = 1.70 for mobility (p = 0.046) and 2.11 for usual activities (p = 0.019). Differences in mental dimensions were only observed among men: aPR = 3.15 for pain/discomfort (p = 0.003) and 2.49 for anxiety/depression (p = 0.030). All these differences by sexual orientation disappeared after adding chronic conditions and health-related behaviors in the models. CONCLUSION: The LGB population presented worse HRQoL than heterosexuals in the EQ-5D index and most dimensions. Chronic conditions, health-related behaviors and gender play a major role in explaining HRQoL differences by sexual orientation. These findings support the need of including sexual orientation into the global agenda of health inequities.
[Mh] Termos MeSH primário: Inquéritos Epidemiológicos
Qualidade de Vida
Comportamento Sexual
Fatores Socioeconômicos
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Doença Crônica/epidemiologia
Feminino
Seres Humanos
Masculino
Meia-Idade
Espanha/epidemiologia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180226
[Lr] Data última revisão:
180226
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180125
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0191334



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