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[PMID]:28466069
[Au] Autor:Castillo-Gómez E; Pérez-Rando M; Bellés M; Gilabert-Juan J; Llorens JV; Carceller H; Bueno-Fernández C; García-Mompó C; Ripoll-Martínez B; Curto Y; Sebastiá-Ortega N; Moltó MD; Sanjuan J; Nacher J
[Ad] Endereço:Neurobiology Unit, Cell Biology Department, Interdisciplinary Research Structure for Biotechnology and Biomedicine (BIOTECMED), Universitat De València, Burjassot 46100, Spain.
[Ti] Título:Early Social Isolation Stress and Perinatal NMDA Receptor Antagonist Treatment Induce Changes in the Structure and Neurochemistry of Inhibitory Neurons of the Adult Amygdala and Prefrontal Cortex.
[So] Source:eNeuro;4(2), 2017 Mar-Apr.
[Is] ISSN:2373-2822
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The exposure to aversive experiences during early life influences brain development and leads to altered behavior. Moreover, the combination of these experiences with subtle alterations in neurodevelopment may contribute to the emergence of psychiatric disorders, such as schizophrenia. Recent hypotheses suggest that imbalances between excitatory and inhibitory (E/I) neurotransmission, especially in the prefrontal cortex and the amygdala, may underlie their etiopathology. In order to understand better the neurobiological bases of these alterations, we studied the impact of altered neurodevelopment and chronic early-life stress on these two brain regions. Transgenic mice displaying fluorescent excitatory and inhibitory neurons, received a single injection of MK801 (NMDAR antagonist) or vehicle solution at postnatal day 7 and/or were socially isolated from the age of weaning until adulthood (3 months old). We found that anxiety-related behavior, brain volume, neuronal structure, and the expression of molecules related to plasticity and E/I neurotransmission in adult mice were importantly affected by early-life stress. Interestingly, many of these effects were potentiated when the stress paradigm was applied to mice perinatally injected with MK801 ("double-hit" model). These results clearly show the impact of early-life stress on the adult brain, especially on the structure and plasticity of inhibitory networks, and highlight the double-hit model as a valuable tool to study the contribution of early-life stress in the emergence of neurodevelopmental psychiatric disorders, such as schizophrenia.
[Mh] Termos MeSH primário: Tonsila do Cerebelo/efeitos dos fármacos
Neurônios/efeitos dos fármacos
Córtex Pré-Frontal/efeitos dos fármacos
Receptores de N-Metil-D-Aspartato/antagonistas & inibidores
Isolamento Social/psicologia
[Mh] Termos MeSH secundário: Tonsila do Cerebelo/metabolismo
Animais
Maleato de Dizocilpina/farmacologia
Camundongos Transgênicos
Plasticidade Neuronal/fisiologia
Neurônios/metabolismo
Receptores de N-Metil-D-Aspartato/metabolismo
Transmissão Sináptica/fisiologia
Sinaptofisina/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Receptors, N-Methyl-D-Aspartate); 0 (Synaptophysin); 6LR8C1B66Q (Dizocilpine Maleate)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170504
[St] Status:MEDLINE


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[PMID]:29179846
[Au] Autor:Patry C; Closier S; Lafon É; Carlier-Verhaeghe C; Kerrien A; Bertrand A; Caudron E
[Ad] Endereço:Hôpital Bretonneau, équipe mobile gériatrique externe, 23 rue Joseph de Maistre, 75018, Paris, France.
[Ti] Título:[Supporting people with Diogenes syndrome].
[Ti] Título:Accompagnement des personnes atteintes du syndrome de Diogène..
[So] Source:Rev Infirm;66(236):34-36, 2017 Dec.
[Is] ISSN:1293-8505
[Cp] País de publicação:France
[La] Idioma:fre
[Ab] Resumo:Diogenes syndrome is a chronic condition often affecting elderly people, especially those living in isolation. It is characterised by self-neglect and compulsive hoarding. Medico-social professionals working with people in their home, have reflected on levers to help improve the complex support of these patients.
[Mh] Termos MeSH primário: Colecionismo
Higiene
Isolamento Social
[Mh] Termos MeSH secundário: Idoso
Colecionismo/diagnóstico
Colecionismo/psicologia
Colecionismo/terapia
Seres Humanos
Síndrome
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180301
[Lr] Data última revisão:
180301
[Sb] Subgrupo de revista:N
[Da] Data de entrada para processamento:171129
[St] Status:MEDLINE


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[PMID]:28460530
[Au] Autor:McGrail MR; Wingrove PM; Petterson SM; Humphreys JS; Russell DJ; Bazemore AW
[Ad] Endereço:School of Rural Health, Northways Rd Churchill VIC 3842 Australia. matthew.mcgrail@monash.edu.
[Ti] Título:Measuring the attractiveness of rural communities in accounting for differences of rural primary care workforce supply.
[So] Source:Rural Remote Health;17(2):3925, 2017 Apr-Jun.
[Is] ISSN:1445-6354
[Cp] País de publicação:Australia
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: Many rural communities continue to experience an undersupply of primary care doctor services. While key professional factors relating to difficulties of recruitment and retention of rural primary care doctors are widely identified, less attention has been given to the role of community and place aspects on supply. Place-related attributes contribute to a community's overall amenity or attractiveness, which arguably influence both rural recruitment and retention relocation decisions of doctors. This bi-national study of Australia and the USA, two developed nations with similar geographic and rural access profiles, investigates the extent to which variations in community amenity indicators are associated with spatial variations in the supply of rural primary care doctors. METHODS: Measures from two dimensions of community amenity: geographic location, specifically isolation/proximity; and economics and sociodemographics were included in this study, along with a proxy measure (jurisdiction) of a third dimension, environmental amenity. Data were chiefly collated from the American Community Survey and the Australian Census of Population and Housing, with additional calculated proximity measures. Rural primary care supply was measured using provider-to-population ratios in 1949 US rural counties and in 370 Australian rural local government areas. Additionally, the more sophisticated two-step floating catchment area method was used to measure Australian rural primary care supply in 1116 rural towns, with population sizes ranging from 500 to 50 000. Associations between supply and community amenity indicators were examined using Pearson's correlation coefficients and ordinary least squares multiple linear regression models. RESULTS: It was found that increased population size, having a hospital in the county, increased house prices and affluence, and a more educated and older population were all significantly associated with increased workforce supply across rural areas of both countries. While remote areas were strongly linked with poorer supply in Australia, geographical remoteness was not significant after accounting for other indicators of amenity such as the positive association between workforce supply and coastal location. Workforce supply in the USA was negatively associated with fringe rural area locations adjacent to larger metropolitan areas and characterised by long work commutes. The US model captured 49% of the variation of workforce supply between rural counties, while the Australian models captured 35-39% of rural supply variation. CONCLUSIONS: These data support the idea that the rural medical workforce is maldistributed with a skew towards locating in more affluent and educated areas, and against locating in smaller, poorer and more isolated rural towns, which struggle to attract an adequate supply of primary care services. This evidence is important in understanding the role of place characteristics and rural population dynamics in the recruitment and retention of rural doctors. Future primary care workforce policies need to place a greater focus on rural communities that, for a variety of reasons, may be less attractive to doctors looking to begin or remain working there.
[Mh] Termos MeSH primário: Recursos Humanos em Saúde/organização & administração
Médicos de Atenção Primária/provisão & distribuição
Atenção Primária à Saúde/organização & administração
Distribuição Espacial da População/estatística & dados numéricos
Serviços de Saúde Rural/recursos humanos
[Mh] Termos MeSH secundário: Austrália
Meio Ambiente
Acesso aos Serviços de Saúde
Seres Humanos
Isolamento Social
Fatores Socioeconômicos
Estados Unidos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180228
[Lr] Data última revisão:
180228
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170503
[St] Status:MEDLINE
[do] DOI:10.22605/RRH3925


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[PMID]:28406387
[Au] Autor:Kattari SK; O'Connor AA; Kattari L
[Ad] Endereço:a Graduate School of Social Work , University of Denver , Denver , Colorado , USA.
[Ti] Título:Development and Validation of the Transgender Inclusive Behavior Scale (TIBS).
[So] Source:J Homosex;65(2):181-196, 2018.
[Is] ISSN:1540-3602
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Transgender-inclusive behaviors are actions and communication supporting transgender individuals. Examples include using language not reinforcing the gender binary, asking for and using correct pronouns, creation of spaces that welcome members of the transgender community, and acknowledging cisgender (non-transgender) privilege. A survey was developed measuring this behavior in individuals to examine the impact of transgender-inclusive behavior and the potential effect of interventions on promoting inclusive behavior. Data were collected utilizing an online survey (N = 1,051). The sample was split in half to run two sets of cases in a principal components analysis. Analysis of the full sample showed Cronbach's alpha to be .93 (n = 918). Findings suggest that the Transgender Inclusive Behavior Scale (TIBS) may be a useful instrument for identifying behaviors related to being inclusive of transgender individuals, groups, and communities. It may also be used to measure behavior change before and after transgender-specific educational and behavioral interventions.
[Mh] Termos MeSH primário: Análise do Comportamento Aplicada/métodos
Pessoas Transgênero/psicologia
Transexualismo/psicologia
[Mh] Termos MeSH secundário: Adulto
Feminino
Identidade de Gênero
Seres Humanos
Masculino
Isolamento Social
Inquéritos e Questionários
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; VALIDATION STUDIES
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180221
[Lr] Data última revisão:
180221
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170414
[St] Status:MEDLINE
[do] DOI:10.1080/00918369.2017.1314160


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[PMID]:29061385
[Au] Autor:Hofford RS; Prendergast MA; Bardo MT
[Ad] Endereço:Department of Psychology, University of Kentucky, Lexington, KY, 40536, USA. Electronic address: rebecca.hofford@uky.edu.
[Ti] Título:Modified single prolonged stress reduces cocaine self-administration during acquisition regardless of rearing environment.
[So] Source:Behav Brain Res;338:143-152, 2018 Feb 15.
[Is] ISSN:1872-7549
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Until recently, there were few rodent models available to study the interaction of post-traumatic stress disorder (PTSD) and drug taking. Like PTSD, single prolonged stress (SPS) produces hypothalamic-pituitary-adrenal (HPA) axis dysfunction and alters psychostimulant self-administration. Other stressors, such as isolation stress, also alter psychostimulant self-administration. However, it is currently unknown if isolation housing combined with SPS can alter the acquisition or maintenance of cocaine self-administration. The current study applied modified SPS (modSPS; two hours restraint immediately followed by cold swim stress) to rats raised in an isolation condition (Iso), enrichment condition (Enr), or standard condition (Std) to measure changes in cocaine self-administration and HPA markers. Regardless of rearing condition, rats exposed to modSPS had greater corticosterone (CORT) release and reduced cocaine self-administration during initial acquisition compared to non-stressed controls. In addition, during initial acquisition, rats that received both Iso rearing and modSPS showed a more rapid increase in cocaine self-administration across sessions compared to Enr and Std rats exposed to modSPS. Following initial acquisition, a dose response analysis showed that Iso rats were overall most sensitive to changes in cocaine unit dose; however, modSPS had no effect on the cocaine dose response curve. Further, there was no effect of either modSPS or differential rearing on expression of glucocorticoid receptor (GR) in hypothalamus, medial prefrontal cortex, amygdala, or nucleus accumbens. By using modSPS in combination with Iso housing, this study identified unique contributions of each stressor to acquisition of cocaine self-administration.
[Mh] Termos MeSH primário: Cocaína/administração & dosagem
Corticosterona/sangue
Inibidores da Captação de Dopamina/administração & dosagem
Receptores de Glucocorticoides/metabolismo
Isolamento Social
Estresse Psicológico/sangue
[Mh] Termos MeSH secundário: Tonsila do Cerebelo/efeitos dos fármacos
Tonsila do Cerebelo/metabolismo
Animais
Abrigo para Animais
Masculino
Núcleo Accumbens/efeitos dos fármacos
Núcleo Accumbens/metabolismo
Córtex Pré-Frontal/efeitos dos fármacos
Córtex Pré-Frontal/metabolismo
Ratos
Ratos Sprague-Dawley
Restrição Física
Autoadministração
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Dopamine Uptake Inhibitors); 0 (Receptors, Glucocorticoid); I5Y540LHVR (Cocaine); W980KJ009P (Corticosterone)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180207
[Lr] Data última revisão:
180207
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171025
[St] Status:MEDLINE


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[PMID]:29237118
[Au] Autor:Tucker J; Wilson A; Clifton VL
[Ti] Título:IMPROVING COMMUNICATION AROUND ANAL INCONTINENCE FOR WOMEN OF REPRODUCTIVE AGE.
[So] Source:Aust Nurs Midwifery J;24(1):37, 2016 07.
[Is] ISSN:2202-7114
[Cp] País de publicação:Australia
[La] Idioma:eng
[Ab] Resumo:Anal incontinence (AI) is the accidental loss of liquid or solid stool and flatus (Milsom et al. 2009). The concept of uncontrolled faecal loss can evoke social disgust and marginalize those afflicted from the community in which they live (Williams et al. 2005).
[Mh] Termos MeSH primário: Incontinência Fecal/etiologia
Incontinência Fecal/enfermagem
Incontinência Fecal/fisiopatologia
Papel do Profissional de Enfermagem
[Mh] Termos MeSH secundário: Adulto
Fatores Etários
Canal Anal/fisiopatologia
Parto Obstétrico/efeitos adversos
Feminino
Seres Humanos
Qualidade de Vida
Isolamento Social
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180118
[Lr] Data última revisão:
180118
[Sb] Subgrupo de revista:N
[Da] Data de entrada para processamento:171214
[St] Status:MEDLINE


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[PMID]:27770374
[Au] Autor:Byker Shanks C; Haack S; Tarabochia D; Bates K; Christenson L
[Ad] Endereço:Food and Health Lab, Department of Health and Human Development, Montana State University, 960 Technology Boulevard, Room 215, Bozeman, MT, 59718, USA. cbykershanks@montana.edu.
[Ti] Título:Factors Influencing Food Choices Among Older Adults in the Rural Western USA.
[So] Source:J Community Health;42(3):511-521, 2017 Jun.
[Is] ISSN:1573-3610
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Nutrition is an essential component in promoting health and quality of life into the older adults years. The purpose of this qualitative research is to explore how the rural food environment influences food choices of older adults. Four focus groups were conducted with 33 older adults (50 years of age and older) residing in rural Montana communities. Four major themes related to factors influencing food choices among rural older adults emerged from this study: perception of the rural community environment, support as a means of increasing food access, personal access to food sources, and dietary factors. The findings from this current study warrant further research and promotion of specifically tailored approaches that influence the food choices of older adults in the rural western USA, including the developing and expanding public transportation systems, increasing availability of local grocers with quality and affordable food options, increasing awareness and decreasing stigma surrounding community food programs, and increasing nutrition education targeting senior health issues.
[Mh] Termos MeSH primário: Comportamento de Escolha
Dieta/estatística & dados numéricos
Comportamento Alimentar
Abastecimento de Alimentos
População Rural/estatística & dados numéricos
[Mh] Termos MeSH secundário: Idoso
Idoso de 80 Anos ou mais
Abastecimento de Alimentos/economia
Abastecimento de Alimentos/estatística & dados numéricos
Seres Humanos
Meia-Idade
Isolamento Social
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180111
[Lr] Data última revisão:
180111
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161023
[St] Status:MEDLINE
[do] DOI:10.1007/s10900-016-0283-6


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[PMID]:28459875
[Au] Autor:Minami C; Shimizu T; Mitani A
[Ad] Endereço:Laboratory of Physiology, Department of Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
[Ti] Título:Neural activity in the prelimbic and infralimbic cortices of freely moving rats during social interaction: Effect of isolation rearing.
[So] Source:PLoS One;12(5):e0176740, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Sociability promotes a sound daily life for individuals. Reduced sociability is a central symptom of various neuropsychiatric disorders, and yet the neural mechanisms underlying reduced sociability remain unclear. The prelimbic cortex (PL) and infralimbic cortex (IL) have been suggested to play an important role in the neural mechanisms underlying sociability because isolation rearing in rats results in impairment of social behavior and structural changes in the PL and IL. One possible mechanism underlying reduced sociability involves dysfunction of the PL and IL. We made a wireless telemetry system to record multiunit activity in the PL and IL of pairs of freely moving rats during social interaction and examined the influence of isolation rearing on this activity. In group-reared rats, PL neurons increased firing when the rat showed approaching behavior and also contact behavior, especially when the rat attacked the partner. Conversely, IL neurons increased firing when the rat exhibited leaving behavior, especially when the partner left on its own accord. In social interaction, the PL may be involved in active actions toward others, whereas the IL may be involved in passive relief from cautionary subjects. Isolation rearing altered social behavior and neural activity. Isolation-reared rats showed an increased frequency and decreased duration of contact behavior. The increased firing of PL neurons during approaching and contact behavior, observed in group-reared rats, was preserved in isolation-reared rats, whereas the increased firing of IL neurons during leaving behavior, observed in group-reared rats, was suppressed in isolation-reared rats. This result indicates that isolation rearing differentially alters neural activity in the PL and IL during social behavior. The differential influence of isolation rearing on neural activity in the PL and IL may be one of the neural bases of isolation rearing-induced behavior.
[Mh] Termos MeSH primário: Córtex Cerebral/fisiopatologia
Neurônios/fisiologia
Comportamento Social
Isolamento Social/psicologia
[Mh] Termos MeSH secundário: Potenciais de Ação
Animais
Comportamento de Escolha/fisiologia
Eletrodos Implantados
Comportamento Exploratório/fisiologia
Abrigo para Animais
Masculino
Atividade Motora/fisiologia
Ratos Sprague-Dawley
Telemetria
Fatores de Tempo
Tecnologia sem Fio
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:171207
[Lr] Data última revisão:
171207
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170502
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0176740


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[PMID]:29045487
[Au] Autor:Umeh NI; Ajegba B; Buscetta AJ; Abdallah KE; Minniti CP; Bonham VL
[Ad] Endereço:Social and Behavioral Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
[Ti] Título:The psychosocial impact of leg ulcers in patients with sickle cell disease: I don't want them to know my little secret.
[So] Source:PLoS One;12(10):e0186270, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Sickle cell disease (SCD) impacts millions of individuals worldwide and more than 100,000 people in the United States. Leg ulcers are the most common cutaneous manifestation of SCD. The health status of individuals living with chronic leg ulcers is not only influenced by clinical manifestations such as pain duration and intensity, but also by psychosocial factors. Garnering insights into the psychosocial impact can provide a more holistic view of their influence on quality of life. METHODS: Semi-structured interviews were conducted with participants living with active SCD-associated leg ulcers or with a history of ulcers. Subjects were recruited from an ongoing study (INSIGHTS, Clin Trial.Gov NCT02156102) and consented to this qualitative phase of the study. Five areas were explored: leg ulcer pain, physical function, social-isolation, social relationships and religious support. Data was collected from 20 individuals during these interviews and a thematic analysis was performed and reported. RESULTS: Twenty participants with a mean age of 42.4 (SD ± 11.1years) were included in the study. Major themes identified included:1) pain (acute and chronic); 2) compromised physical function as demonstrated by decreased ability to walk, run, and play sports; 3) social isolation from activities either by others or self-induced as a means of avoiding certain emotions, such as embarrassment; 4) social relationships (family support and social network); 5) support and comfort through their religion or spirituality. CONCLUSIONS: SCD patients with leg ulcers expressed that they experience social isolation, intense and frequent ulcer pain, and difficulty in physical function. SCD-associated leg ulcers have been studied from a clinical approach, but the psychosocial factors investigated in this study informs how quality of life is impacted by the leg ulcers.
[Mh] Termos MeSH primário: Anemia Falciforme/psicologia
Úlcera da Perna/psicologia
Isolamento Social/psicologia
[Mh] Termos MeSH secundário: Adulto
Anemia Falciforme/fisiopatologia
Feminino
Seres Humanos
Entrevista Psicológica
Úlcera da Perna/fisiopatologia
Masculino
Meia-Idade
Medição da Dor/psicologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171031
[Lr] Data última revisão:
171031
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171019
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0186270


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[PMID]:29036201
[Au] Autor:Soliani FCBG; Cabbia R; Batistela MF; Almeida AG; Kümpel VD; Yamauchi Junior L; Andrade TGCS
[Ad] Endereço:Laboratory of Physiology, UNESP-Univ Estadual Paulista, Assis, São Paulo, Brazil.
[Ti] Título:Impact of social separation during pregnancy on the manifestation of defensive behaviors related to generalized anxiety and panic throughout offspring development.
[So] Source:PLoS One;12(10):e0185572, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The multiple insecurities, anatomical, physiological and psychological changes arising from the gestational period can generate an overload of stress in the mother and cause disturbances in the offspring, affecting it throughout its development. The existing analysis linking prenatal stress and offspring's anxiety have divergent results, being limited as to gestational week, type of stressor and age of progeny's assessment. Social separation has been described as a stressor that causes increase in anxiety. Thus, the present study evaluated the effects of social separation applied in one of the three gestational weeks of rat dams on the manifestation of the defensive behaviors related to generalized anxiety disorder and panic in the Elevated T Maze of the male progeny in three stages of development (1, 3 or 6 months of life). It was found, in the offspring of grouped (control) dams, increased behaviors associated with generalized anxiety disorder and a reduction of panic-like behaviors throughout development. For animals whose dams were socially separated during pregnancy, the most critical period of exposure was the 2nd gestational week, which affected the acquisition of aversive memory, demonstrated by the impairment on learning of avoidances of the offspring in all ages evaluated. Stressor exposure in this week also increased the avoidances, related to generalized anxiety of progeny in the 1st month and decreased escapes, related to panic in the 3rd month of life and, at the age of 6 months old, an inverse situation, with the reduction of the defensive behaviors associated to generalized anxiety disorder. The results show that, when assessing effects of prenatal stress on the manifestation of anxiety, not only the period of exposure is important, but also the age of offspring assessed.
[Mh] Termos MeSH primário: Ansiedade
Pânico
Efeitos Tardios da Exposição Pré-Natal
Comportamento Social
Isolamento Social
[Mh] Termos MeSH secundário: Envelhecimento/psicologia
Animais
Ansiedade/etiologia
Aprendizagem da Esquiva
Feminino
Masculino
Memória
Modelos Animais
Gravidez
Efeitos Tardios da Exposição Pré-Natal/psicologia
Ratos Wistar
Isolamento Social/psicologia
Estresse Psicológico
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171031
[Lr] Data última revisão:
171031
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171017
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0185572



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