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[PMID]:28749452
[Au] Autor:Yokoshima S; Morihara T; Sato T; Yano T
[Ad] Endereço:Kanagawa Environmental Research Center, 1-3-39 Shinomiya, Hiratsuka, Kanagawa 254-0014, Japan. yokoshima.7c7q@pref.kanagawa.jp.
[Ti] Título:Combined Effects of High-Speed Railway Noise and Ground Vibrations on Annoyance.
[So] Source:Int J Environ Res Public Health;14(8), 2017 07 27.
[Is] ISSN:1660-4601
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:The Shinkansen super-express railway system in Japan has greatly increased its capacity and has expanded nationwide. However, many inhabitants in areas along the railways have been disturbed by noise and ground vibration from the trains. Additionally, the Shinkansen railway emits a higher level of ground vibration than conventional railways at the same noise level. These findings imply that building vibrations affect living environments as significantly as the associated noise. Therefore, it is imperative to quantify the effects of noise and vibration exposures on each annoyance under simultaneous exposure. We performed a secondary analysis using individual datasets of exposure and community response associated with Shinkansen railway noise and vibration. The data consisted of six socio-acoustic surveys, which were conducted separately over the last 20 years in Japan. Applying a logistic regression analysis to the datasets, we confirmed the combined effects of vibration/noise exposure on noise/vibration annoyance. Moreover, we proposed a representative relationship between noise and vibration exposures, and the prevalence of each annoyance associated with the Shinkansen railway.
[Mh] Termos MeSH primário: Ruído dos Transportes/efeitos adversos
Ferrovias
Vibração/efeitos adversos
[Mh] Termos MeSH secundário: Adulto
Afeto
Idoso
Meio Ambiente
Exposição Ambiental
Feminino
Seres Humanos
Japão
Masculino
Meia-Idade
Inquéritos e Questionários
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180305
[Lr] Data última revisão:
180305
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170728
[St] Status:MEDLINE


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[PMID]:28462933
[Au] Autor:Craig A; Guest R; Tran Y; Middleton J
[Ad] Endereço:John Walsh Centre for Rehabilitation Research, Sydney Medical School-Northern, The University of Sydney, St Leonards, NSW, Australia.
[Ti] Título:Depressive mood in adults with spinal cord injury as they transition from an inpatient to a community setting: secondary analyses from a clinical trial.
[So] Source:Spinal Cord;55(10):926-934, 2017 Oct.
[Is] ISSN:1476-5624
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:STUDY DESIGN: Prospective cohort controlled trial design. OBJECTIVES: (i) To investigate mood benefits of adding group cognitive behaviour therapy (group-CBT) to standard spinal cord injury (SCI) inpatient rehabilitation (SR) that included access to antidepressant medication and individually delivered CBT on demand. (ii) To determine whether those with elevated depressive mood during inpatient rehabilitation significantly improve. SETTING: SCI rehabilitation and community settings in New South Wales, Australia. METHODS: Participants included 50 adults with SCI who completed SCI rehabilitation that included group-CBT compared with 38 participants who also completed SCI rehabilitation that did not contain group-CBT. Comprehensive assessment occurred after admission, within 2 weeks of discharge and 12 months post-injury. Multivariate repeated measures analyses were conducted to examine differences between groups and over time. RESULTS: The addition of group-CBT to SR did not result in significant improvement in mood. However, participants with clinically elevated depressive mood assessed during inpatient rehabilitation experienced significant reductions in depressive mood when assessed in the community regardless of CBT dosage. Anxiety correlated with mood while no sociodemographic/injury factors correlated with mood at any time period except education level. CONCLUSION: There were no mood advantages over time of adding group-CBT to inpatient SCI rehabilitation that contains individually delivered CBT on demand and access to antidepressant medication. However, findings showed those with elevated depressive mood during inpatient rehabilitation significantly improved when assessed in the community; however, their levels of depressive mood remain high. Future research should investigate the efficacy of providing individual preferences for managing depression in people with SCI.
[Mh] Termos MeSH primário: Depressão
Traumatismos da Medula Espinal/psicologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Afeto
Idoso
Idoso de 80 Anos ou mais
Ansiedade/terapia
Terapia Cognitiva
Depressão/terapia
Escolaridade
Feminino
Seres Humanos
Vida Independente
Pacientes Internados/psicologia
Masculino
Meia-Idade
Reabilitação Neurológica
Psicoterapia de Grupo
Traumatismos da Medula Espinal/reabilitação
Resultado do Tratamento
Adulto Jovem
[Pt] Tipo de publicação:CONTROLLED CLINICAL TRIAL; JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180302
[Lr] Data última revisão:
180302
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170503
[St] Status:MEDLINE
[do] DOI:10.1038/sc.2017.41


  3 / 27885 MEDLINE  
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[PMID]:29386455
[Au] Autor:Takai R; Nomura K; Hiraike H; Murakami A; Tanabe A; Tsuchiya A; Okinaga H
[Ad] Endereço:Faculty of Nursing, Toho University.
[Ti] Título:[An Investigation of Factors Associated with Emotional Exhaustion among Hospital Nurses: Adherence to "Maternal Affection" and Agreement with Stereotypical Gender Roles].
[So] Source:Nihon Eiseigaku Zasshi;73(1):90-95, 2018.
[Is] ISSN:1882-6482
[Cp] País de publicação:Japan
[La] Idioma:jpn
[Ab] Resumo:OBJECTIVE: To investigate factors including adherence to "maternal affection" and stereotypical gender roles associated with emotional exhaustion among hospital nurses. METHOD: In 2014, among 2,690 workers recruited for this study, 891 participated with written informed consent. Of these, we investigated 464 hospital nurses. Adherence to maternal affection and emotional exhaustion were measured using valid and reliable scales developed by Egami (2005, 12 items) and Kubo (1992, 5 items), respectively. Stereotypical gender role was measured by asking "how much do you agree with the idea that women should stay home and men should work?". Workfamily conflict was measured in terms of the discrepancy in priority in life (i.e., a work or a private life) between the participant's ideal and the real world. RESULT: The majority of our participants were women (86%), aged 39 or younger (80%), and single (70%). About one-quarter had workfamily conflict (26%) and agreed with the stereotypical gender role (28%). The mean scores of emotional exhaustion and adherence to maternal affection were 17.2 (out of 25) and 30.8 (out of 48), respectively. A stepwise multivariable model showed that being a woman (p=0.028), being young (p=0.022), being single (p=0.007), and having workfamily conflict (p<0.001) were more likely to increase emotional exhaustion after adjusting for household income. Adherence to maternal affection and stereotypical gender role were not significantly associated with emotional exhaustion. CONCLUSION: This study demonstrated that adherence to "maternal affection" and stereotypical gender roles were not associated with psychological burnout. Special attention should be paid to hospital nurses who are women, young, or single, or who have workfamily conflict.
[Mh] Termos MeSH primário: Afeto
Esgotamento Profissional/psicologia
Emoções
Identidade de Gênero
Hospitais
Comportamento Materno/psicologia
Enfermeiras e Enfermeiros/psicologia
Estereotipagem
[Mh] Termos MeSH secundário: Adulto
Conflito Familiar
Feminino
Seres Humanos
Masculino
Meia-Idade
Inquéritos e Questionários
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180228
[Lr] Data última revisão:
180228
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180202
[St] Status:MEDLINE
[do] DOI:10.1265/jjh.73.90


  4 / 27885 MEDLINE  
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[PMID]:29361988
[Au] Autor:Yoto A; Fukui N; Kaneda C; Torita S; Goto K; Nanjo F; Yokogoshi H
[Ad] Endereço:School of Food and Nutritional Sciences, University of Shizuoka, Shizuoka, Japan. ai_yoto@hotmail.com.
[Ti] Título:Black tea aroma inhibited increase of salivary chromogranin-A after arithmetic tasks.
[So] Source:J Physiol Anthropol;37(1):3, 2018 Jan 24.
[Is] ISSN:1880-6805
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Growing attention has been paid to the effects of food flavor components on alleviating negative brain functions caused by stressful lifestyles. In this study, we investigated the alleviating effect of two kinds of black tea aromas on physical and psychological stress induced by the Uchida-Kraepelin test, based on salivary chromogranin-A (CgA) levels as a stress marker and subjective evaluations (Profile of Mood States). RESULTS: Compared with the water exposure control, inhaling black tea aroma (Darjeeling and Assam in this study) induced lower salivary CgA concentration levels after 30 min of mental stress load tasks. This anti-stress effect of black tea aroma did not differ between the two tea types even though the concentration of the anti-stress components in the Darjeeling tea aroma was higher than that in the Assam aroma. However, Darjeeling tea aroma tended to decrease the tension and/or anxiety score immediately after the first exposure. CONCLUSIONS: Inhaling black tea aroma may diminish stress levels caused by arithmetic mental stress tasks, and Darjeeling tea aroma tended to improve mood before mental stress load.
[Mh] Termos MeSH primário: Afeto/efeitos dos fármacos
Cromogranina A/análise
Odorantes/análise
Saliva/química
Estresse Psicológico/metabolismo
Chá
[Mh] Termos MeSH secundário: Adulto
Ansiedade/metabolismo
Feminino
Seres Humanos
Masculino
Análise e Desempenho de Tarefas
Escala Visual Analógica
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Chromogranin A); 0 (Tea)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180223
[Lr] Data última revisão:
180223
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180125
[St] Status:MEDLINE
[do] DOI:10.1186/s40101-018-0163-0


  5 / 27885 MEDLINE  
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[PMID]:29205721
[Au] Autor:Awad A; Cipriani A
[Ad] Endereço:Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK.
[Ti] Título:Prophylactic mood stabilization: What is the evidence for lithium exposure in drinking water?
[So] Source:Bipolar Disord;19(7):601-602, 2017 11.
[Is] ISSN:1399-5618
[Cp] País de publicação:Denmark
[La] Idioma:eng
[Mh] Termos MeSH primário: Água Potável/análise
Lítio/análise
[Mh] Termos MeSH secundário: Afeto
Transtorno Bipolar
Seres Humanos
Suicídio
[Pt] Tipo de publicação:JOURNAL ARTICLE; COMMENT
[Nm] Nome de substância:
0 (Drinking Water); 9FN79X2M3F (Lithium)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180222
[Lr] Data última revisão:
180222
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171206
[St] Status:MEDLINE
[do] DOI:10.1111/bdi.12541


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[PMID]:27774839
[Au] Autor:Jeong HS; Choi EK; Song IU; Chung YA; Park JS; Oh JK
[Ad] Endereço:1 Department of Radiology, Incheon St. Mary's Hospital, The Catholic University of Korea , Incheon, South Korea .
[Ti] Título:Differences in Brain Glucose Metabolism During Preparation for I Ablation in Thyroid Cancer Patients: Thyroid Hormone Withdrawal Versus Recombinant Human Thyrotropin.
[So] Source:Thyroid;27(1):23-28, 2017 Jan.
[Is] ISSN:1557-9077
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: In preparation for I ablation, temporary withdrawal of thyroid hormone is commonly used in patients with thyroid cancer after total thyroidectomy. The current study aimed to investigate brain glucose metabolism and its relationships with mood or cognitive function in these patients using F-fluoro-2-deoxyglucose positron emission tomography ( F-FDG-PET). METHOD: A total of 40 consecutive adult patients with thyroid carcinoma who had undergone total thyroidectomy were recruited for this cross-sectional study. At the time of assessment, 20 patients were hypothyroid after two weeks of thyroid hormone withdrawal, while 20 received thyroid hormone replacement therapy and were euthyroid. All participants underwent brain F-FDG-PET scans and completed mood questionnaires and cognitive tests. Multivariate spatial covariance analysis and univariate voxel-wise analysis were applied for the image data. RESULTS: The hypothyroid patients were more anxious and depressed than the euthyroid participants. The multivariate covariance analysis showed increases in glucose metabolism primarily in the bilateral insula and surrounding areas and concomitant decreases in the parieto-occipital regions in the hypothyroid group. The level of thyrotropin was positively associated with the individual expression of the covariance pattern. The decreased F-FDG uptake in the right cuneus cluster from the univariate analysis was correlated with the increased thyrotropin level and greater depressive symptoms in the hypothyroid group. CONCLUSIONS: These results suggest that temporary hypothyroidism, even for a short period, may induce impairment in glucose metabolism and related affective symptoms.
[Mh] Termos MeSH primário: Encéfalo/metabolismo
Glucose/metabolismo
Neoplasias da Glândula Tireoide/metabolismo
[Mh] Termos MeSH secundário: Adulto
Afeto/fisiologia
Ansiedade/diagnóstico por imagem
Ansiedade/metabolismo
Ansiedade/psicologia
Encéfalo/diagnóstico por imagem
Cognição/fisiologia
Estudos Transversais
Depressão/diagnóstico por imagem
Depressão/metabolismo
Depressão/psicologia
Feminino
Fluordesoxiglucose F18
Seres Humanos
Radioisótopos do Iodo/uso terapêutico
Masculino
Meia-Idade
Tomografia por Emissão de Pósitrons
Neoplasias da Glândula Tireoide/diagnóstico por imagem
Neoplasias da Glândula Tireoide/psicologia
Neoplasias da Glândula Tireoide/radioterapia
Tireoidectomia
Tireotropina/sangue
Tiroxina/sangue
Tri-Iodotironina/sangue
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Iodine Radioisotopes); 06LU7C9H1V (Triiodothyronine); 0Z5B2CJX4D (Fluorodeoxyglucose F18); 9002-71-5 (Thyrotropin); IY9XDZ35W2 (Glucose); Q51BO43MG4 (Thyroxine)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180222
[Lr] Data última revisão:
180222
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161025
[St] Status:MEDLINE
[do] DOI:10.1089/thy.2016.0293


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[PMID]:29293636
[Au] Autor:Monk JE; Doyle RE; Colditz IG; Belson S; Cronin GM; Lee C
[Ad] Endereço:Agriculture and Food, CSIRO, Armidale, NSW, Australia.
[Ti] Título:Towards a more practical attention bias test to assess affective state in sheep.
[So] Source:PLoS One;13(1):e0190404, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Tests for attention bias potentially offer more rapid assessment of affective state in animals than existing cognitive methods. An attention bias test has previously been developed for sheep and validated as a measure of anxious states. The 3 minute test assessed behavioural responses of sheep in an enclosed arena after brief exposure to the threat of a dog. Experiment 1 of the current study aimed to refine the previously developed method, removing the need for a habituation period and shortening the test duration. Sheep were given either an anxiolytic drug, an anxiogenic drug or a control treatment prior to testing to induce contrasting affective states. Differences in behaviour were found between the treatment groups within the first 45s of the test, indicating the original test duration could be shortened from 180 s. During testing, 36 of 40 animals in the control and anxiolytic groups ate the novel feed offered in the test, indicating it is not necessary to habituate animals to a feed container. Experiment 2 aimed to confirm the responses measured in the test were primarily towards the dog rather than other aspects of the test environment. Sheep exposed to an empty window at the beginning of the test behaved differently to those which were exposed to a dog, indicating sheep behaviour in the test is at least partially a response to the dog. A third group of sheep were also tested with the dog immediately after having small data loggers attached to their necks. Behaviour of these sheep did not differ from the sheep tested without loggers, indicating data logger attachment did not impact their behaviour in the test. In both experiments, treatments did not appear to modify activity (zones crossed), which we propose indicates the test was primarily detecting valence of the affective state rather than arousal.
[Mh] Termos MeSH primário: Afeto
Ovinos/fisiologia
[Mh] Termos MeSH secundário: Afeto/efeitos dos fármacos
Ração Animal
Animais
Ansiolíticos/administração & dosagem
Atenção
Comportamento Animal
Cães
Masculino
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Anti-Anxiety Agents)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180221
[Lr] Data última revisão:
180221
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180103
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0190404


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[PMID]:29184209
[Au] Autor:Rodriguez E; Sakurai K; Xu J; Chen Y; Toda K; Zhao S; Han BX; Ryu D; Yin H; Liedtke W; Wang F
[Ad] Endereço:Department of Neurobiology, Duke University Medical Center, Durham, NC, USA.
[Ti] Título:A craniofacial-specific monosynaptic circuit enables heightened affective pain.
[So] Source:Nat Neurosci;20(12):1734-1743, 2017 Dec.
[Is] ISSN:1546-1726
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Humans often rank craniofacial pain as more severe than body pain. Evidence suggests that a stimulus of the same intensity induces stronger pain in the face than in the body. However, the underlying neural circuitry for the differential processing of facial versus bodily pain remains unknown. Interestingly, the lateral parabrachial nucleus (PB ), a critical node in the affective pain circuit, is activated more strongly by noxious stimulation of the face than of the hindpaw. Using a novel activity-dependent technology called CANE developed in our laboratory, we identified and selectively labeled noxious-stimulus-activated PB neurons and performed comprehensive anatomical input-output mapping. Surprisingly, we uncovered a hitherto uncharacterized monosynaptic connection between cranial sensory neurons and the PB -nociceptive neurons. Optogenetic activation of this monosynaptic craniofacial-to-PB projection induced robust escape and avoidance behaviors and stress calls, whereas optogenetic silencing specifically reduced facial nociception. The monosynaptic circuit revealed here provides a neural substrate for heightened craniofacial affective pain.
[Mh] Termos MeSH primário: Dor Facial/fisiopatologia
Dor Facial/psicologia
Nociceptores
Sinapses
[Mh] Termos MeSH secundário: Afeto
Vias Aferentes/fisiopatologia
Animais
Comportamento Animal
Condicionamento Operante
Feminino
Genes fos/genética
Masculino
Camundongos
Camundongos Endogâmicos C57BL
Optogenética
Estimulação Física
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1712
[Cu] Atualização por classe:180222
[Lr] Data última revisão:
180222
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171130
[St] Status:MEDLINE
[do] DOI:10.1038/s41593-017-0012-1


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[PMID]:28463238
[Au] Autor:Jonker I; Rosmalen JGM; Schoevers RA
[Ad] Endereço:Department of Psychiatry, Interdisciplinary Center for Psychopathology and Emotion Regulation (ICPE), University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
[Ti] Título:Childhood life events, immune activation and the development of mood and anxiety disorders: the TRAILS study.
[So] Source:Transl Psychiatry;7(5):e1112, 2017 May 02.
[Is] ISSN:2158-3188
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The experience of childhood life events is associated with higher vulnerability to develop psychiatric disorders. One of the pathways suggested to lead to this vulnerability is activation of the immune system. The aim of this study is to find out whether the association between childhood life events and the development of mood and anxiety disorders is predicted by the activation of the immune system. This study was performed in TRAILS, a large prospective population cohort, from which a subgroup was selected (N=1084, 54.3% female, mean age 19.0 (s.d., 0.6)). Childhood life events before age 16 were assessed using questionnaires at age 12, 14, 16 and 19. Immune activation was assessed at age 16 by elevated high-sensitive C-reactive protein (hsCRP) and by levels of immunoglobulin G antibodies against the herpes viruses herpes simplex virus 1, cytomegalovirus and Epstein-Barr virus. At age 19, the presence of mood and anxiety disorders was determined using the World Health Organization Composite International Diagnostic Interview Version 3.0. Regression analyses were used to study the association between life events, the inflammatory markers and mental health. We found that childhood life events score was associated with risk of mood disorders (B=0.269, P<0.001) and anxiety disorders (B=0.129, P<0.001). Childhood life events score was marginally associated with elevated hsCRP (B=0.076, P=0.006), but not with the antibody levels. This was especially due to separation trauma (P=0.015) and sexual abuse (P=0.019). Associations lost significance after correcting for lifestyle factors such as body mass index and substance abuse (P=0.042). None of the inflammatory markers were associated with development of anxiety disorders or mood disorders. In conclusion, the life event scores predicted the development of anxiety disorders and mood disorders at age 19. Life event scores were associated with elevated hsCRP, which was partly explained by lifestyle factors. Elevated hsCRP was not associated with the development of psychiatric disorders at age 19.
[Mh] Termos MeSH primário: Afeto/fisiologia
Transtornos de Ansiedade/diagnóstico
Fenômenos do Sistema Imunológico/fisiologia
Acontecimentos que Mudam a Vida
Transtornos do Humor/diagnóstico
[Mh] Termos MeSH secundário: Adolescente
Transtornos de Ansiedade/epidemiologia
Transtornos de Ansiedade/imunologia
Transtornos de Ansiedade/metabolismo
Índice de Massa Corporal
Proteína C-Reativa/metabolismo
Feminino
Seres Humanos
Imunoglobulina G/metabolismo
Masculino
Transtornos do Humor/epidemiologia
Países Baixos
Valor Preditivo dos Testes
Estudos Prospectivos
Transtornos Relacionados ao Uso de Substâncias/epidemiologia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Immunoglobulin G); 9007-41-4 (C-Reactive Protein)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180220
[Lr] Data última revisão:
180220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170503
[St] Status:MEDLINE
[do] DOI:10.1038/tp.2017.62


  10 / 27885 MEDLINE  
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[PMID]:29061386
[Au] Autor:Klumpp H; Bhaumik R; Kinney KL; Fitzgerald JM
[Ad] Endereço:Department of Psychiatry (HK, RB), University of Illinois at Chicago, Chicago, IL, United States; Department of Psychology (HK, KLK), University of Illinois at Chicago, Chicago, IL, United States. Electronic address: hklumpp@psych.uic.edu.
[Ti] Título:Principal component analysis and neural predictors of emotion regulation.
[So] Source:Behav Brain Res;338:128-133, 2018 Feb 15.
[Is] ISSN:1872-7549
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Reappraisal, a cognitive approach intended to alter an emotional response, is generally associated with prefrontal cortical recruitment and decreased limbic activity. However, the extent to which neurofunctional activity predicts successful reappraisal is unclear. During fMRI, 60 healthy participants completed a reappraisal paradigm, which included reappraising negative images to reduce emotional reactivity ('ReappNeg') and viewing negative images and experiencing the negative affect they evoke ('LookNeg'). After each trial, participants rated their emotional response on a Likert-type scale where higher values indicated more negative affect. Reappraisal ability was based on a difference value (ΔReappNeg-LookNeg) such that negative values signified successful reappraisal ('SR'; n=38) and positive values, unsuccessful reappraisal ('USR'; n=22). Neural activity based on ReappNeg-LookNeg conditions from 37 regions of interest encompassing cortical and limbic areas was submitted to Principal Component Analysis (PCA). Resulting PCA factors were submitted to discriminant function analysis to evaluate which factor(s) predicted SR and USR groups. Results showed a factor with high loadings for certain frontal areas (e.g., left dorsomedial prefrontal cortex) and limbic regions (e.g., bilateral amygdala) predicted 71.1% of cases in the SR group and 68.2% of cases in the USR group. Additionally, successful reappraisal corresponded with more activation in the factor with high loadings for frontal areas and less activity in the factor associated with limbic regions. Results are consistent with studies of individual differences where more prefrontal engagement and less limbic activity is associated with effectual reappraisal, but for the first time, a neural 'signature' for successful reappraisal has been demonstrated.
[Mh] Termos MeSH primário: Encéfalo/diagnóstico por imagem
Cognição/fisiologia
Emoções/fisiologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Afeto/fisiologia
Encéfalo/fisiologia
Mapeamento Encefálico
Feminino
Neuroimagem Funcional
Seres Humanos
Imagem por Ressonância Magnética
Masculino
Análise de Componente Principal
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180218
[Lr] Data última revisão:
180218
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171025
[St] Status:MEDLINE



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