Base de dados : MEDLINE
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[PMID]:29364978
[Au] Autor:Stickley A; Koyanagi A
[Ad] Endereço:The Stockholm Center for Health and Social Change (SCOHOST), Södertörn University, Huddinge, Sweden.
[Ti] Título:Physical multimorbidity and loneliness: A population-based study.
[So] Source:PLoS One;13(1):e0191651, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Multimorbidity has been linked to a variety of negative outcomes although as yet, there has been little research on its association with loneliness. This study examined the association between physical multimorbidity (≥ 2 physical diseases) and loneliness in the general population and its potential mediators. Data came from the Adult Psychiatric Morbidity Survey 2007 (N = 7403, aged ≥16 years). Information was obtained on 20 doctor diagnosed physical conditions that were present in the previous year. An item from the Social Functioning Questionnaire (SFQ) was used to obtain information on loneliness. Multivariable logistic regression analysis was used to examine associations. An increasing number of physical diseases was associated with higher odds for loneliness. Compared to no physical diseases, the odds ratio (OR) (95% confidence interval: CI) for loneliness increased from 1.34 (1.13-1.59) to 2.82 (2.11-3.78) between one and ≥5 physical diseases. This association was particularly strong in the youngest age group (i.e. 16-44 years). The loneliness-physical multimorbidity association was significantly mediated by stressful life events (% mediated 11.1%-30.5%), anxiety (30.2%), and depression (15.4%). Physical multimorbidity is associated with increased odds for loneliness. Prospective research is now needed to further elucidate this association and the factors that underlie it.
[Mh] Termos MeSH primário: Solidão
Multimorbidade
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Feminino
Seres Humanos
Masculino
Meia-Idade
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180125
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0191651


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[PMID]:29273588
[Au] Autor:Black J
[Ad] Endereço:Malvern WR14 2JW, UK.
[Ti] Título:Loneliness and tiredness resulting from the European Working Time Regulations.
[So] Source:BMJ;359:j5775, 2017 12 22.
[Is] ISSN:1756-1833
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Solidão
Carga de Trabalho/legislação & jurisprudência
[Mh] Termos MeSH secundário: Grupo com Ancestrais do Continente Europeu
Fadiga
Seres Humanos
[Pt] Tipo de publicação:LETTER; COMMENT
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180212
[Lr] Data última revisão:
180212
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171224
[St] Status:MEDLINE
[do] DOI:10.1136/bmj.j5775


  3 / 2786 MEDLINE  
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[PMID]:27775406
[Au] Autor:English T; Davis J; Wei M; Gross JJ
[Ad] Endereço:Department of Psychological and Brain Sciences, Washington University in St. Louis.
[Ti] Título:Homesickness and adjustment across the first year of college: A longitudinal study.
[So] Source:Emotion;17(1):1-5, 2017 Feb.
[Is] ISSN:1931-1516
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Homesickness can put individuals at risk for a host of adjustment difficulties. The millions of students that leave home for college each year may be particularly susceptible to experiencing homesickness. There is little work, however, examining individual variation in homesickness over time and how these changes predict different outcomes in college. The present study examines weekly levels of homesickness during the first term of college and tests the associations between homesickness and various aspects of adjustment. Results showed that, on average, homesickness decreased slightly across the first semester of college, but there were individual differences in homesickness trajectories. Freshmen who reported higher levels of homesickness showed worse overall adjustment to college, even when controlling for negative emotional experience and prior adjustment. Homesickness was associated with poorer social outcomes, but these social difficulties were limited to interactions with others in the college environment. Academic outcomes were not adversely impacted by homesickness. Findings suggest that homesickness is a common experience for freshmen, and, despite its relatively transient nature, homesickness has important implications for college adjustment. (PsycINFO Database Record
[Mh] Termos MeSH primário: Emoções/fisiologia
Solidão/psicologia
Estudantes/psicologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Feminino
Seres Humanos
Estudos Longitudinais
Masculino
Universidades
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1707
[Cu] Atualização por classe:180201
[Lr] Data última revisão:
180201
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161028
[St] Status:MEDLINE
[do] DOI:10.1037/emo0000235


  4 / 2786 MEDLINE  
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[PMID]:29300743
[Au] Autor:Rico-Uribe LA; Caballero FF; Martín-María N; Cabello M; Ayuso-Mateos JL; Miret M
[Ad] Endereço:Department of Psychiatry, Universidad Autónoma de Madrid, Madrid, Spain.
[Ti] Título:Association of loneliness with all-cause mortality: A meta-analysis.
[So] Source:PLoS One;13(1):e0190033, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: Loneliness has social and health implications. The aim of this article is to evaluate the association of loneliness with all-cause mortality. METHODS: Pubmed, PsycINFO, CINAHL and Scopus databases were searched through June 2016 for published articles that measured loneliness and mortality. The main characteristics and the effect size values of each article were extracted. Moreover, an evaluation of the quality of the articles included was also carried out. A meta-analysis was performed firstly with all the included articles and secondly separating by gender, using a random effects model. RESULTS: A total of 35 articles involving 77220 participants were included in the systematic review. Loneliness is a risk factor for all-cause mortality [pooled HR = 1.22, 95% CI = (1.10, 1.35), p < 0.001] for both genders together, and for women [pooled HR = 1.26, 95% CI = (1.07, 1.48); p = 0.005] and men [pooled HR = 1.44; 95% CI = (1.19, 1.76); p < 0.001] separately. CONCLUSIONS: Loneliness shows a harmful effect for all-cause mortality and this effect is slightly stronger in men than in women. Moreover, the impact of loneliness was independent from the quality evaluation of each article and the effect of depression.
[Mh] Termos MeSH primário: Causas de Morte
Solidão
[Mh] Termos MeSH secundário: Seres Humanos
Fatores de Risco
[Pt] Tipo de publicação:JOURNAL ARTICLE; META-ANALYSIS; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180129
[Lr] Data última revisão:
180129
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180105
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0190033


  5 / 2786 MEDLINE  
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Texto completo SciELO Colômbia
Texto completo SciELO Saúde Pública
[PMID]:28453139
[Au] Autor:Zapata-López BI; Delgado-Villamizar NL; Cardona-Arango D
[Ad] Endereço:Universidad CES, Medellín, Colombia, dcardona@ces.edu.co.
[Ti] Título:[Social and family support to the elderly in urban areas].
[Ti] Título:Apoyo social y familiar al adulto mayor del área urbana en Angelópolis, Colombia 2011..
[So] Source:Rev Salud Publica (Bogota);17(6):848-860, 2015 Dec.
[Is] ISSN:0124-0064
[Cp] País de publicação:Colombia
[La] Idioma:spa
[Ab] Resumo:Objective To describe the social and family support networks available to the elderly living in urban areas of the municipality of Angelópolis-Antioquia during the year 2011. Materials A descriptive transversal study was conductedusing the population experience to determine the social support received by the 239 seniors in the urban area of Angelópolis-Antioquia. The data was obtained from primary sources and univariate and bivariate analysis was conducted. Results Mostly women were interviewed (59.8 %) aged between 60 and 74 (66.9 %). The social status that appeared with the highest percentage was "married" (47.3 %) though with the interviewed women the social status with the highest occurrence was "widow" (40.6 %). 69,5 % had an elementary school educational level and 16,7 % had no formal education at all. 60.3 % were registered in the subsidized program. The support from families and friends was qualified as satisfactory. A statistically significant connection was found between gender and undertaking different activities in free time (value of p=0,004). Conclusions the study indicates that loneliness is an aspect that makes the elderly feel unprotected and vulnerable. Despite the general feeling of satisfaction regarding family support, some of them, especially women, expressed feeling mistreated. The data along with the lack of activities for spare time must be taken into account to formulate intervention strategies for effective support networks to improve the situation of this vulnerable population of the municipality.
[Mh] Termos MeSH primário: Envelhecimento/psicologia
Relações Familiares/psicologia
Apoio Social
Saúde da População Urbana
[Mh] Termos MeSH secundário: Idoso
Idoso de 80 Anos ou mais
Colômbia
Estudos Transversais
Maus-Tratos ao Idoso/psicologia
Maus-Tratos ao Idoso/estatística & dados numéricos
Feminino
Seres Humanos
Atividades de Lazer/psicologia
Solidão
Masculino
Estado Civil/estatística & dados numéricos
Meia-Idade
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180117
[Lr] Data última revisão:
180117
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170429
[St] Status:MEDLINE


  6 / 2786 MEDLINE  
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[PMID]:27779518
[Au] Autor:Stam M; Smit JH; Twisk JW; Lemke U; Smits C; Festen JM; Kramer SE
[Ad] Endereço:1Section Ear & Hearing, Department of Otolaryngology-Head and Neck Surgery, VU University Medical Center and EMGO Institute for Health and Care Research, Amsterdam, The Netherlands; 2Department of Psychiatry, VU University Medical Center/GGZ inGeest and EMGO Institute for Health and Care Research, Amsterdam, The Netherlands; 3Department of Epidemiology and Biostatistics, VU University Medical Center and EMGO Institute for Health and Care Research, Amsterdam, The Netherlands; and 4Phonak AG, Science and Technology, Stäfa, Switzerland.
[Ti] Título:Change in Psychosocial Health Status Over 5 Years in Relation to Adults' Hearing Ability in Noise.
[So] Source:Ear Hear;37(6):680-689, 2016 Nov/Dec.
[Is] ISSN:1538-4667
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: The aim of this study was to establish the longitudinal relationship between hearing ability in noise and psychosocial health outcomes (i.e., loneliness, anxiety, depression, distress, and somatization) in adults aged 18 to 70 years. An additional objective was to determine whether a change in hearing ability in noise over a period of 5 years was associated with a change in psychosocial functioning. Subgroup effects for a range of factors were investigated. DESIGN: Longitudinal data of the web-based Netherlands Longitudinal Study on Hearing (NL-SH) (N = 508) were analyzed. The ability to recognize speech in noise (i.e., the speech-reception-threshold [SRTn]) was measured with an online digit triplet test at baseline and at 5-year follow-up. Psychosocial health status was assessed by online questionnaires. Multiple linear regression analyses and longitudinal statistical analyses (i.e., generalized estimating equations) were performed. RESULTS: Poorer SRTn was associated longitudinally with more feelings of emotional and social loneliness. For participants with a high educational level, the longitudinal association between SRTn and social loneliness was significant. Changes in hearing ability and loneliness appeared significantly associated only for specific subgroups: those with stable pattern of hearing aid nonuse (increased emotional and social loneliness), who entered matrimony (increased social loneliness), and low educational level (less emotional loneliness). No significant longitudinal associations were found between hearing ability and anxiety, depression, distress, or somatization. CONCLUSIONS: Hearing ability in noise was longitudinally associated with loneliness. Decline in hearing ability in noise was related to increase in loneliness for specific subgroups of participants. One of these subgroups included participants whose hearing deteriorated over 5 years, but who continued to report nonuse of hearing aids. This is an important and alarming finding that needs further investigation.
[Mh] Termos MeSH primário: Ansiedade/psicologia
Depressão/psicologia
Nível de Saúde
Perda Auditiva/psicologia
Audição
Solidão/psicologia
Transtornos Somatoformes/psicologia
Estresse Psicológico/psicologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Escolaridade
Feminino
Auxiliares de Audição
Perda Auditiva/fisiopatologia
Perda Auditiva/reabilitação
Seres Humanos
Estudos Longitudinais
Masculino
Saúde Mental
Meia-Idade
Ruído
Percepção da Fala
Teste do Limiar de Recepção da Fala
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180117
[Lr] Data última revisão:
180117
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161026
[St] Status:MEDLINE


  7 / 2786 MEDLINE  
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[PMID]:27777375
[Au] Autor:Bartz JA; Tchalova K; Fenerci C
[Ad] Endereço:Department of Psychology, McGill University.
[Ti] Título:Reminders of Social Connection Can Attenuate Anthropomorphism.
[So] Source:Psychol Sci;27(12):1644-1650, 2016 Dec.
[Is] ISSN:1467-9280
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:It is a fundamental human need to secure and sustain a sense of social belonging. Previous research has shown that individuals who are lonely are more likely than people who are not lonely to attribute humanlike traits (e.g., free will) to nonhuman agents (e.g., an alarm clock that makes people get up by moving away from the sleeper), presumably in an attempt to fulfill unmet needs for belongingness. We directly replicated the association between loneliness and anthropomorphism in a larger sample ( N = 178); furthermore, we showed that reminding people of a close, supportive relationship reduces their tendency to anthropomorphize. This finding provides support for the idea that the need for belonging has causal effects on anthropomorphism. Last, we showed that attachment anxiety-characterized by intense desire for and preoccupation with closeness, fear of abandonment, and hypervigilance to social cues-was a stronger predictor of anthropomorphism than loneliness was. This finding helps clarify the mechanisms underlying anthropomorphism and supports the idea that anthropomorphism is a motivated process reflecting the active search for potential sources of connection.
[Mh] Termos MeSH primário: Solidão/psicologia
Motivação/fisiologia
Percepção Social
[Mh] Termos MeSH secundário: Adulto
Ansiedade/psicologia
Sinais (Psicologia)
Feminino
Seres Humanos
Masculino
Meia-Idade
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180108
[Lr] Data última revisão:
180108
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161026
[St] Status:MEDLINE
[do] DOI:10.1177/0956797616668510


  8 / 2786 MEDLINE  
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[PMID]:29240816
[Au] Autor:Marijuán PC; Montero-Marín J; Navarro J; García-Campayo J; Del Moral R
[Ad] Endereço:Bioinformation Group, Aragon Institute of Health Science (IACS), Zaragoza, Spain.
[Ti] Título:The "sociotype" construct: Gauging the structure and dynamics of human sociality.
[So] Source:PLoS One;12(12):e0189568, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Exploring the pertinence of a "sociotype" construct, established along the conceptual chain genotype-phenotype-sociotype, is the essential purpose of the present paper. Further, by following the sociotype's conceptual guidelines, a new psychometric indicator has been developed in order to gauge the level of social interaction around each individual-the sociotype questionnaire (SOCQ). A first version of this questionnaire has been elaborated by gathering data about the different classes of social bonds (family, friends, acquaintances, and work/study colleagues) in general population and about the dynamic update of these bonds via face-to-face conversation and other modes of interaction. A specific fieldwork was undertaken, involving 1,075 participants, all of them Spanish adults (with diverse social and regional backgrounds). The data obtained were analyzed by means of the correlational method with an analytical cross-sectional design: the number of factors and the consistency and reliability of the resulting scales were evaluated and correlated. The new sociotype indicator resulting from that fieldwork, in spite of its limitations, seems to be valid and reliable, as well as closely associated with widely used metrics of loneliness and psychological distress. It is interesting that the construct noticeably varies throughout the life course and circumstances of individuals, based on their gender and age, and adjusting to the different situations of social networking. This is the first study, to the best of our knowledge, which has tried to reach both a theoretical and an operational formulation of the sociotype construct, by establishing an ad hoc psychometric questionnaire. We think that the information provided by this operational definition opens a new direction of work that could be useful to guide the development and evaluation of programs aimed at improving and strengthening social networking in people at risk, especially for the elderly.
[Mh] Termos MeSH primário: Relações Interpessoais
[Mh] Termos MeSH secundário: Adulto
Fatores Etários
Idoso
Análise Fatorial
Feminino
Seres Humanos
Solidão
Masculino
Meia-Idade
Psicometria
Reprodutibilidade dos Testes
Fatores Sexuais
Estresse Psicológico
Inquéritos e Questionários
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171229
[Lr] Data última revisão:
171229
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171215
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0189568


  9 / 2786 MEDLINE  
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[PMID]:29211726
[Au] Autor:Tillmann T; Pikhart H; Peasey A; Kubinova R; Pajak A; Tamosiunas A; Malyutina S; Steptoe A; Kivimäki M; Marmot M; Bobak M
[Ad] Endereço:Department of Epidemiology & Public Health, University College London, London, United Kingdom.
[Ti] Título:Psychosocial and socioeconomic determinants of cardiovascular mortality in Eastern Europe: A multicentre prospective cohort study.
[So] Source:PLoS Med;14(12):e1002459, 2017 Dec.
[Is] ISSN:1549-1676
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Eastern European countries have some of the highest rates of cardiovascular disease (CVD) mortality, much of which cannot be adequately accounted for by conventional CVD risk factors. Psychosocial and socioeconomic factors may affect risk of CVD, but relatively few studies on this issue have been undertaken in Eastern Europe. We investigated whether various psychosocial factors are associated with CVD mortality independently from each other and whether they can help explain differences in CVD mortality between Eastern European populations. METHODS: Participants were from the Health, Alcohol and Psychological factors in Eastern Europe (HAPIEE) cohort study in Russia, Poland and the Czech Republic, including a total of 20,867 men and women aged 43-74 years and free of CVD at baseline examination during 2002-2005. Participants were followed-up for CVD mortality after linkage to national mortality registries for a median of 7.2 years. RESULTS: During the follow-up, 556 participants died from CVD. After mutual adjustment, six psychosocial and socioeconomic factors were associated with increased risk of CVD death: unemployment, low material amenities, depression, being single, infrequent contacts with friends or relatives. The hazard ratios [HRs] for these six factors ranged between 1.26 [95% confidence interval 1.14-1.40] and 1.81 [95% confidence interval 1.24-2.64], fully adjusted for each other, and conventional cardiovascular risk factors. Population-attributable fractions ranged from 8% [4%-13%] to 22% [11%-31%] for each factor, when measured on average across the three cohorts. However, the prevalence of psychosocial and socioeconomic risk factors and their HRs were similar between the three countries. Altogether, these factors could not explain why participants from Russia had higher CVD mortality when compared to participants from Poland/Czech Republic. Limitations of this study include measurement error that could lead to residual confounding; and the possibilities for reverse causation and/or unmeasured confounding from observational studies to lead to associations that are not causal in nature. CONCLUSIONS: Six psychosocial and socioeconomic factors were associated with cardiovascular mortality, independent of each other. Differences in mortality between cohorts from Russia versus Poland or Check Republic remained unexplained.
[Mh] Termos MeSH primário: Doenças Cardiovasculares
Depressão
Solidão
Psicologia
Fatores Socioeconômicos
[Mh] Termos MeSH secundário: Adulto
Idoso
Doenças Cardiovasculares/epidemiologia
Doenças Cardiovasculares/mortalidade
Doenças Cardiovasculares/psicologia
Comorbidade
República Tcheca/epidemiologia
Demografia
Depressão/epidemiologia
Depressão/fisiopatologia
Feminino
Seres Humanos
Masculino
Meia-Idade
Polônia/epidemiologia
Estudos Prospectivos
Fatores de Risco
Federação Russa/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; MULTICENTER STUDY
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171220
[Lr] Data última revisão:
171220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171207
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pmed.1002459


  10 / 2786 MEDLINE  
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[PMID]:28449673
[Au] Autor:Lindsay Smith G; Banting L; Eime R; O'Sullivan G; van Uffelen JGZ
[Ad] Endereço:Institute of Sport, Exercise and Active Living, Victoria University, Melbourne, Australia. gabrielle.lindsaysmith@live.vu.edu.au.
[Ti] Título:The association between social support and physical activity in older adults: a systematic review.
[So] Source:Int J Behav Nutr Phys Act;14(1):56, 2017 04 27.
[Is] ISSN:1479-5868
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The promotion of active and healthy ageing is becoming increasingly important as the population ages. Physical activity (PA) significantly reduces all-cause mortality and contributes to the prevention of many chronic illnesses. However, the proportion of people globally who are active enough to gain these health benefits is low and decreases with age. Social support (SS) is a social determinant of health that may improve PA in older adults, but the association has not been systematically reviewed. This review had three aims: 1) Systematically review and summarise studies examining the association between SS, or loneliness, and PA in older adults; 2) clarify if specific types of SS are positively associated with PA; and 3) investigate whether the association between SS and PA differs between PA domains. METHODS: Quantitative studies examining a relationship between SS, or loneliness, and PA levels in healthy, older adults over 60 were identified using MEDLINE, PSYCInfo, SportDiscus, CINAHL and PubMed, and through reference lists of included studies. Quality of these studies was rated. RESULTS: This review included 27 papers, of which 22 were cross sectional studies, three were prospective/longitudinal and two were intervention studies. Overall, the study quality was moderate. Four articles examined the relation of PA with general SS, 17 with SS specific to PA (SSPA), and six with loneliness. The results suggest that there is a positive association between SSPA and PA levels in older adults, especially when it comes from family members. No clear associations were identified between general SS, SSPA from friends, or loneliness and PA levels. When measured separately, leisure time PA (LTPA) was associated with SS in a greater percentage of studies than when a number of PA domains were measured together. CONCLUSIONS: The evidence surrounding the relationship between SS, or loneliness, and PA in older adults suggests that people with greater SS for PA are more likely to do LTPA, especially when the SS comes from family members. However, high variability in measurement methods used to assess both SS and PA in included studies made it difficult to compare studies.
[Mh] Termos MeSH primário: Exercício
Apoio Social
[Mh] Termos MeSH secundário: Idoso
Família
Feminino
Amigos
Seres Humanos
Solidão
Masculino
Meia-Idade
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171127
[Lr] Data última revisão:
171127
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170429
[St] Status:MEDLINE
[do] DOI:10.1186/s12966-017-0509-8



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