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Pesquisa : F01.658.209 [Categoria DeCS]
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[PMID]:29441971
[Au] Autor:Rutkowska M; Slupski W; Trocha M; Szandruk M; Rymaszewska J
[Ti] Título:The anxiolytic activity of n-3 PUFAs enriched egg yolk phospholipids in rat behavioral studies.
[So] Source:Pharmazie;71(11):655-659, 2016 11 02.
[Is] ISSN:0031-7144
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Phospholipids play an important role in the biochemical and physiological processes of cells. An association between disturbed phospholipids metabolism in neuronal tissue and anxiety it was shown. The aim of this study was to examine the anxiolytic properties of phospholipids obtained from a new generation of eggs enriched in n-3 PUFA and its effect on locomotor activity in rat behavioral studies N-3 PUFA-enriched egg yolk phospholipids ("super lecithin") were added to the standard feed. Rats were fed by chow without (control group) or with (experimental group) addition of phospholipids. After six weeks of supplementation, the effect of phospholipids on locomotor activity in the open field test and anxiolytic properties in elevated plus maze and Vogel conflict test were examined. In the open field test the total distance traveled in the experimental group was similar to the control group. In the elevated plus maze test a six weeks phospholipids' administration significantly prolonged the time spent on the open arms by rats from experimental group compared to control group. The number of entries into the open arms was also increased but the difference was not statistically significant. The number of punished drinking water in the Vogel conflict test increased significantly in experimental versus control group. The obtained results suggest that the phospholipids isolated from n-3 PUFA enriched egg yolk have a specific anxiolytic effect, without general sedative influence.
[Mh] Termos MeSH primário: Ansiolíticos/farmacologia
Comportamento Animal/efeitos dos fármacos
Gema de Ovo/química
Ácidos Graxos Ômega-3/farmacologia
Fosfolipídeos/farmacologia
[Mh] Termos MeSH secundário: Animais
Conflito (Psicologia)
Comportamento Exploratório/efeitos dos fármacos
Masculino
Atividade Motora/efeitos dos fármacos
Ratos
Ratos Wistar
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Anxiety Agents); 0 (Fatty Acids, Omega-3); 0 (Phospholipids)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180215
[St] Status:MEDLINE
[do] DOI:10.1691/ph.2016.6646


  2 / 15497 MEDLINE  
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[PMID]:29289272
[Au] Autor:Shuker O; Khamaisi M
[Ad] Endereço:Internal Medicine Department, Institute of Endocrinology, Diabetes & Metabolism, Rambam Health Care Campus, Haifa, Israel; Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
[Ti] Título:When Patient/Family Expectations and Hospital Protocol Conflict.
[So] Source:Am J Med Sci;355(1):99-100, 2018 Jan.
[Is] ISSN:1538-2990
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Conflito (Psicologia)
Família/psicologia
Transferência de Pacientes
Polimiosite
[Mh] Termos MeSH secundário: Feminino
Seres Humanos
Masculino
Meia-Idade
Polimiosite/psicologia
Polimiosite/terapia
[Pt] Tipo de publicação:CASE REPORTS; EDITORIAL
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180301
[Lr] Data última revisão:
180301
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180101
[St] Status:MEDLINE


  3 / 15497 MEDLINE  
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[PMID]:29329355
[Au] Autor:Beaton LE; Azma S; Marinkovic K
[Ad] Endereço:Department of Psychology, San Diego State University, San Diego, California, United States of America.
[Ti] Título:When the brain changes its mind: Oscillatory dynamics of conflict processing and response switching in a flanker task during alcohol challenge.
[So] Source:PLoS One;13(1):e0191200, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Despite the subjective experience of being in full and deliberate control of our actions, our daily routines rely on a continuous and interactive engagement of sensory evaluation and response preparation streams. They unfold automatically and unconsciously and are seamlessly integrated with cognitive control which is mobilized by stimuli that evoke ambiguity or response conflict. Methods with high spatio-temporal sensitivity are needed to provide insight into the interplay between automatic and controlled processing. This study used anatomically-constrained MEG to examine the underlying neural dynamics in a flanker task that manipulated S-R incongruity at the stimulus (SI) and response levels (RI). Though irrelevant, flankers evoked automatic preparation of motor plans which had to be suppressed and reversed following the target presentation on RI trials. Event-related source power estimates in beta (15-25 Hz) frequency band in the sensorimotor cortex tracked motor preparation and response in real time and revealed switching from the incorrectly-primed to the correctly-responding hemisphere. In contrast, theta oscillations (4-7 Hz) were sensitive to the levels of incongruity as the medial and ventrolateral frontal cortices were especially activated by response conflict. These two areas are key to cognitive control and their integrated contributions to response inhibition and switching were revealed by phase-locked co-oscillations. These processes were pharmacologically manipulated with a moderate alcohol beverage or a placebo administered to healthy social drinkers. Alcohol selectively decreased accuracy to response conflict. It strongly attenuated theta oscillations during decision making and partly re-sculpted relative contributions of the frontal network without affecting the motor switching process subserved by beta band. Our results indicate that motor preparation is initiated automatically even when counterproductive but that it is monitored and regulated by the prefrontal cognitive control processes under conflict. They further confirm that the regulative top-down functions are particularly vulnerable to alcohol intoxication.
[Mh] Termos MeSH primário: Consumo de Bebidas Alcoólicas/fisiopatologia
Consumo de Bebidas Alcoólicas/psicologia
Encéfalo/fisiologia
Conflito (Psicologia)
[Mh] Termos MeSH secundário: Adulto
Intoxicação Alcoólica/fisiopatologia
Intoxicação Alcoólica/psicologia
Ritmo beta/efeitos dos fármacos
Ritmo beta/fisiologia
Encéfalo/diagnóstico por imagem
Encéfalo/efeitos dos fármacos
Mapeamento Encefálico
Cognição/efeitos dos fármacos
Cognição/fisiologia
Etanol/efeitos adversos
Feminino
Neuroimagem Funcional
Seres Humanos
Imagem por Ressonância Magnética
Magnetoencefalografia
Masculino
Córtex Pré-Frontal/diagnóstico por imagem
Córtex Pré-Frontal/efeitos dos fármacos
Córtex Pré-Frontal/fisiologia
Desempenho Psicomotor/efeitos dos fármacos
Desempenho Psicomotor/fisiologia
Ritmo Teta/efeitos dos fármacos
Ritmo Teta/fisiologia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL
[Nm] Nome de substância:
3K9958V90M (Ethanol)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180226
[Lr] Data última revisão:
180226
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180113
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0191200


  4 / 15497 MEDLINE  
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[PMID]:29195529
[Au] Autor:Zealand R; Larkin D; Shron M
[Ad] Endereço:Education Department, School of Arts and Sciences, The College of New Rochelle, New Rochelle, New York, USA.
[Ti] Título:Building Relationship-Based Care Among Nurses: A Holistic, Exploratory Project.
[So] Source:Creat Nurs;22(3):185-195, 2016 Aug 01.
[Is] ISSN:1078-4535
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:In this exploratory project, efforts were made to strengthen a relationship-centered, caring milieu to improve communication among nursing staff and to help nurses identify and constructively resolve conflicts. Eighteen interactive workshops addressed communication patterns and helped participants identify causes of conflict, facilitate dialogue, improve collaboration, and resolve workplace conflict. The experiential workshops were analyzed with pre- and post-surveys. Participants perceived as individual and team members that it was less important to like one's colleagues and more important to be committed to the same purpose/goals. Individuals noted the value of respect for each other, regardless of title or position. They reported feeling more hopeful regarding work and that practicing tactics to address conflicts made it easier to confront others when the team goal was clear and shared. They indicated a desire to continue to build on conflict resolution, mediation, stress management, and mindfulness skills.
[Mh] Termos MeSH primário: Comunicação
Negociação/psicologia
Relações Enfermeiro-Paciente
Cuidados de Enfermagem/psicologia
Recursos Humanos de Enfermagem no Hospital/educação
Recursos Humanos de Enfermagem no Hospital/psicologia
Assistência Centrada no Paciente/métodos
[Mh] Termos MeSH secundário: Adulto
Idoso
Idoso de 80 Anos ou mais
Conflito (Psicologia)
Comportamento Cooperativo
Currículo
Feminino
Enfermagem Holística/métodos
Seres Humanos
Satisfação no Emprego
Masculino
Meia-Idade
Inquéritos e Questionários
Estados Unidos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180220
[Lr] Data última revisão:
180220
[Sb] Subgrupo de revista:N
[Da] Data de entrada para processamento:171203
[St] Status:MEDLINE
[do] DOI:10.1891/1078-4535.22.3.185


  5 / 15497 MEDLINE  
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[PMID]:28459655
[Au] Autor:Kysil EV; Meshalkina DA; Frick EE; Echevarria DJ; Rosemberg DB; Maximino C; Lima MG; Abreu MS; Giacomini AC; Barcellos LJG; Song C; Kalueff AV
[Ad] Endereço:1 Institute of Translational Biomedicine, St. Petersburg State University , St. Petersburg, Russia .
[Ti] Título:Comparative Analyses of Zebrafish Anxiety-Like Behavior Using Conflict-Based Novelty Tests.
[So] Source:Zebrafish;14(3):197-208, 2017 06.
[Is] ISSN:1557-8542
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Modeling of stress and anxiety in adult zebrafish (Danio rerio) is increasingly utilized in neuroscience research and central nervous system (CNS) drug discovery. Representing the most commonly used zebrafish anxiety models, the novel tank test (NTT) focuses on zebrafish diving in response to potentially threatening stimuli, whereas the light-dark test (LDT) is based on fish scototaxis (innate preference for dark vs. bright areas). Here, we systematically evaluate the utility of these two tests, combining meta-analyses of published literature with comparative in vivo behavioral and whole-body endocrine (cortisol) testing. Overall, the NTT and LDT behaviors demonstrate a generally good cross-test correlation in vivo, whereas meta-analyses of published literature show that both tests have similar sensitivity to zebrafish anxiety-like states. Finally, NTT evokes higher levels of cortisol, likely representing a more stressful procedure than LDT. Collectively, our study reappraises NTT and LDT for studying anxiety-like states in zebrafish, and emphasizes their developing utility for neurobehavioral research. These findings can help optimize drug screening procedures by choosing more appropriate models for testing anxiolytic or anxiogenic drugs.
[Mh] Termos MeSH primário: Ansiedade/psicologia
Conflito (Psicologia)
Atividade Motora/fisiologia
Peixe-Zebra/fisiologia
[Mh] Termos MeSH secundário: Animais
Comportamento Animal
Escuridão
Modelos Animais de Doenças
Hidrocortisona/análise
Luz
Estresse Psicológico
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
WI4X0X7BPJ (Hydrocortisone)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:180116
[Lr] Data última revisão:
180116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170502
[St] Status:MEDLINE
[do] DOI:10.1089/zeb.2016.1415


  6 / 15497 MEDLINE  
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[PMID]:28448839
[Au] Autor:Naefgen C; Caissie AF; Janczyk M
[Ad] Endereço:Eberhard Karls University Tübingen, Department of Psychology, Schleichstraße 4, 72076 Tübingen, Germany. Electronic address: christoph.naefgen@uni-tuebingen.de.
[Ti] Título:Stimulus-response links and the backward crosstalk effect - A comparison of forced- and free-choice tasks.
[So] Source:Acta Psychol (Amst);177:23-29, 2017 Jun.
[Is] ISSN:1873-6297
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:In dual-tasks, characteristics of Task 2 responses can already affect performance in the preceding Task 1. This is called the backward crosstalk effect (BCE). To account for the BCE, it has been suggested that the appearance of the Task 2 stimulus automatically projects activation onto the corresponding response through (transient or direct) stimulus-response (S-R) links. One way to investigate this claim is to compare the size of the BCE for tasks where S-R links are differently strong. To this end, we here compared BCEs for forced- vs. free-choice tasks, with the S-R links assumed to be stronger in the former than in the latter task. In Experiments 1 and 2, Task 1 was either forced-choice or free-choice and Task 2 always forced-choice, and in Experiment 3 this order was reversed. A BCE was observed in all experiments with the forced-choice tasks, but in response times it was smaller in Experiments 1 and 2 and absent in Experiment 3 with the free-choice task. However, in free-choice Task 1 responses, a bias towards selecting the response required in Task 2 was observed. These results suggest that the strength of S-R links plays a role in determining the size of the BCE. Relations to other studies and alternative explanations are discussed.
[Mh] Termos MeSH primário: Comportamento de Escolha/fisiologia
Conflito (Psicologia)
Desempenho Psicomotor/fisiologia
Tempo de Reação/fisiologia
[Mh] Termos MeSH secundário: Feminino
Seres Humanos
Masculino
Testes Neuropsicológicos
Adulto Jovem
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171222
[Lr] Data última revisão:
171222
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170428
[St] Status:MEDLINE


  7 / 15497 MEDLINE  
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[PMID]:28786988
[Au] Autor:Halko ML; Miettinen T
[Ad] Endereço:Department of Political and Economic Studies, University of Helsinki, Helsinki, Finland.
[Ti] Título:From ideals to deals-The effect of impartiality experience on stakeholder behavior.
[So] Source:PLoS One;12(8):e0182263, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:In this paper, we study a two-party pie-sharing problem in the presence of asymmetries in the stakeholders' private endowments. Both the two stakeholders and third-party arbitrators may influence the outcome. We consider Nash-demand negotiations, where the two stakeholders place demands and share the pie accordingly if demands are compatible, and elicit dictatorial allocations from the stakeholders and the arbitrators. The Nash demands by stakeholders are strategic; the dictatorial allocations by stakeholders and arbitrators are non-strategic. We are interested in the influence of the past arbitrator experience on stakeholder allocations and demands and the past stakeholder experience on third-party arbitration allocations. We find that the ex-arbitrators' stakeholder allocations differ more from the impartial ideal than the stakeholder allocations by those without arbitration experience. In contrast with previous findings, the arbitration outcomes do not depend on the asymmetries in the previous stakeholder roles.
[Mh] Termos MeSH primário: Comportamento Cooperativo
Negociação
[Mh] Termos MeSH secundário: Conflito (Psicologia)
Jogos Experimentais
Seres Humanos
Julgamento
Modelos Psicológicos
Distribuição Aleatória
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171004
[Lr] Data última revisão:
171004
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170809
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0182263


  8 / 15497 MEDLINE  
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[PMID]:28626018
[Au] Autor:Khemka S; Barnes G; Dolan RJ; Bach DR
[Ad] Endereço:Division of Clinical Psychiatry Research, University of Zurich, 8032 Zürich, Switzerland.
[Ti] Título:Dissecting the Function of Hippocampal Oscillations in a Human Anxiety Model.
[So] Source:J Neurosci;37(29):6869-6876, 2017 Jul 19.
[Is] ISSN:1529-2401
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Neural oscillations in hippocampus and medial prefrontal cortex (mPFC) are a hallmark of rodent anxiety models that build on conflict between approach and avoidance. Yet, the function of these oscillations, and their expression in humans, remain elusive. Here, we used magnetoencephalography (MEG) to investigate neural oscillations in a task that simulated approach-avoidance conflict, wherein 23 male and female human participants collected monetary tokens under a threat of virtual predation. Probability of threat was signaled by color and learned beforehand by direct experience. Magnitude of threat corresponded to a possible monetary loss, signaled as a quantity. We focused our analyses on an a priori defined region-of-interest, the bilateral hippocampus. Oscillatory power under conflict was linearly predicted by threat probability in a location consistent with right mid-hippocampus. This pattern was specific to the hippocampus, most pronounced in the gamma band, and not explained by spatial movement or anxiety-like behavior. Gamma power was modulated by slower theta rhythms, and this theta modulation increased with threat probability. Furthermore, theta oscillations in the same location showed greater synchrony with mPFC theta with increased threat probability. Strikingly, these findings were not seen in relation to an increase in threat magnitude, which was explicitly signaled as a quantity and induced similar behavioral responses as learned threat probability. Thus, our findings suggest that the expression of hippocampal and mPFC oscillatory activity in the context of anxiety is specifically linked to threat memory. These findings resonate with neurocomputational accounts of the role played by hippocampal oscillations in memory. We use a biologically relevant approach-avoidance conflict test in humans while recording neural oscillations with magnetoencephalography to investigate the expression and function of hippocampal oscillations in human anxiety. Extending nonhuman studies, we can assign a possible function to hippocampal oscillations in this task, namely threat memory communication. This blends into recent attempts to elucidate the role of brain synchronization in defensive responses to threat.
[Mh] Termos MeSH primário: Ansiedade/fisiopatologia
Aprendizagem da Esquiva
Relógios Biológicos
Ondas Encefálicas
Conflito (Psicologia)
Hipocampo/fisiopatologia
[Mh] Termos MeSH secundário: Feminino
Seres Humanos
Masculino
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170818
[Lr] Data última revisão:
170818
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170620
[St] Status:MEDLINE
[do] DOI:10.1523/JNEUROSCI.1834-16.2017


  9 / 15497 MEDLINE  
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[PMID]:28585509
[Au] Autor:Kaufhold J; Negele A; Leuzinger-Bohleber M; Kallenbach L; Ernst M; Bahrke U
[Ad] Endereço:Sigmund-Freud-Institut Myliusstr. 20 60323 Frankfurt amMain Deutschland Sigmund-Freud-Institut.
[Ti] Título:[Conflict dynamics in chronic depression - Results of the conflict and structure axis using the OPD in the LAC Study].
[Ti] Título:Zur Konfliktdynamik bei chronischer Depression ­ Ergebnisse zur Konflikt- und Strukturachse der OPD in der LAC-Studie..
[So] Source:Z Psychosom Med Psychother;63(2):151-162, 2017 Jun.
[Is] ISSN:1438-3608
[Cp] País de publicação:Germany
[La] Idioma:ger
[Mh] Termos MeSH primário: Conflito (Psicologia)
Transtorno Depressivo/psicologia
Transtorno Distímico/psicologia
Teoria Psicanalítica
Autoimagem
[Mh] Termos MeSH secundário: Adulto
Terapia Comportamental
Doença Crônica
Dependência (Psicologia)
Transtorno Depressivo/diagnóstico
Transtorno Depressivo/terapia
Transtorno Distímico/diagnóstico
Transtorno Distímico/terapia
Feminino
Seres Humanos
Individuação
Assistência de Longa Duração/psicologia
Masculino
Meia-Idade
Aceitação pelo Paciente de Cuidados de Saúde/psicologia
Terapia Psicanalítica
Resultado do Tratamento
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:171004
[Lr] Data última revisão:
171004
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170607
[St] Status:MEDLINE
[do] DOI:10.13109/zptm.2017.63.2.151


  10 / 15497 MEDLINE  
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[PMID]:28582425
[Au] Autor:Pozo RA; Coulson T; McCulloch G; Stronza AL; Songhurst AC
[Ad] Endereço:Department of Zoology, University of Oxford, Oxford, United Kingdom.
[Ti] Título:Determining baselines for human-elephant conflict: A matter of time.
[So] Source:PLoS One;12(6):e0178840, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Elephant crop raiding is one of the most relevant forms of human-elephant conflict (HEC) in Africa. Northern Botswana holds the largest population of African elephants in the world, and in the eastern Okavango Panhandle, 16,000 people share and compete for resources with more than 11,000 elephants. Hence, it is not surprising this area represents a HEC 'hotspot' in the region. Crop-raiding impacts lead to negative perceptions of elephants by local communities, which can strongly undermine conservation efforts. Therefore, assessing trends in conflict levels is essential to developing successful management strategies. In this context, we investigated the trend in the number of reported raiding incidents as one of the indicators of the level of HEC, and assessed its relationship to trends in human and elephant population size, as well as land-use in the study area. For each of these factors, we considered data spanning historical (since the 1970s) and contemporary (2008-2015) time frames, with the aim of comparing subsequent inferences on the drivers of crop raiding and predictions for the future. We find that the level of reported crop raiding by elephants in the eastern Panhandle appears to have decreased since 2008, which seems to be related to the reduction in agricultural land allocated to people in recent years, more than with human and elephant population size. We show that inferences regarding the drivers of HEC and predictions for the future are dependent on the time span of the data used. Although our study represents a first step in developing a HEC baseline in the eastern Panhandle, it highlights the need for additional multi-scale analyses that consider progress in conservation conflict to better understand and predict drivers of HEC in the region.
[Mh] Termos MeSH primário: Conflito (Psicologia)
Conservação dos Recursos Naturais
Elefantes/fisiologia
Comportamento Alimentar/fisiologia
Modelos Estatísticos
[Mh] Termos MeSH secundário: Animais
Botsuana
Produtos Agrícolas
Feminino
Seres Humanos
Masculino
Densidade Demográfica
População Rural/estatística & dados numéricos
Fatores de Tempo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170919
[Lr] Data última revisão:
170919
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170606
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0178840



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