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Pesquisa : F01.829.263.500.320.892 [Categoria DeCS]
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[PMID]:29210255
[Au] Autor:Boggio A
[Ti] Título:The Legalisation of Gamete Donation in Italy.
[So] Source:Eur J Health Law;24(1):85-104, 2017 Mar.
[Is] ISSN:0929-0273
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Since 2004, the regulation of assisted reproduction in Italy has undergone substantial reform as an effect of key judicial intervention. Limitations on embryo production, screening and transfer, the prohibition against engaging in preimplantation genetic diagnosis (PGD) and embryo selection, and the ban on gamete donation have all been removed by courts. In this article, I discuss how judicial intervention has improved the ability of Italian couples to access assisted reproduction technologies (ARTs), and how the expansion of reproductive rights is, however, still incomplete. In particular, I discuss the challenges in implementing the liberalisation of gamete donation, and identify the practical, political and cultural reasons for limited access to gamete donation. I also discuss the future of the prohibitions and restrictions that still exist in Law 40/2004.
[Mh] Termos MeSH primário: Destinação do Embrião/legislação & jurisprudência
Doação de Oócitos/legislação & jurisprudência
Técnicas de Reprodução Assistida/legislação & jurisprudência
[Mh] Termos MeSH secundário: Seres Humanos
Itália
Mães Substitutas/legislação & jurisprudência
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171228
[Lr] Data última revisão:
171228
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171207
[St] Status:MEDLINE


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[PMID]:29202976
[Au] Autor:Woo I; Hindoyan R; Landay M; Ho J; Ingles SA; McGinnis LK; Paulson RJ; Chung K
[Ad] Endereço:Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Los Angeles, California. Electronic address: irene.woo@med.usc.edu.
[Ti] Título:Perinatal outcomes after natural conception versus in vitro fertilization (IVF) in gestational surrogates: a model to evaluate IVF treatment versus maternal effects.
[So] Source:Fertil Steril;108(6):993-998, 2017 Dec.
[Is] ISSN:1556-5653
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To study the perinatal outcomes between singleton live births achieved with the use of commissioned versus spontaneously conceived embryos carried by the same gestational surrogate. DESIGN: Retrospective cohort study. SETTING: Academic in vitro fertilization center. PATIENT(S): Gestational surrogate. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Pregnancy outcome, gestational age at birth, birth weight, perinatal complications. RESULT(S): We identified 124 gestational surrogates who achieved a total of 494 pregnancies. Pregnancy outcomes for surrogate and spontaneous pregnancies were significantly different (P<.001), with surrogate pregnancies more likely to result in twin pregnancies: 33% vs. 1%. Miscarriage and ectopic rates were similar. Of these pregnancies, there were 352 singleton live births: 103 achieved from commissioned embryos and 249 conceived spontaneously. Surrogate births had lower mean gestational age at delivery (38.8 ± 2.1 vs. 39.7 ± 1.4), higher rates of preterm birth (10.7% vs. 3.1%), and higher rates of low birth weight (7.8% vs. 2.4%). Neonates from surrogacy had birth weights that were, on average, 105 g lower. Surrogate births had significantly higher obstetrical complications, including gestational diabetes, hypertension, use of amniocentesis, placenta previa, antibiotic requirement during labor, and cesarean section. CONCLUSION(S): Neonates born from commissioned embryos and carried by gestational surrogates have increased adverse perinatal outcomes, including preterm birth, low birth weight, hypertension, maternal gestational diabetes, and placenta previa, compared with singletons conceived spontaneously and carried by the same woman. Our data suggest that assisted reproductive procedures may potentially affect embryo quality and that its negative impact can not be overcome even with a proven healthy uterine environment.
[Mh] Termos MeSH primário: Transferência Embrionária
Fertilidade
Fertilização In Vitro
Mães Substitutas
[Mh] Termos MeSH secundário: Adulto
Peso ao Nascer
Transferência Embrionária/efeitos adversos
Feminino
Fertilização In Vitro/efeitos adversos
Idade Gestacional
Seres Humanos
Recém-Nascido
Nascimento Vivo
Gravidez
Complicações na Gravidez/etiologia
Taxa de Gravidez
Estudos Retrospectivos
Fatores de Risco
Resultado do Tratamento
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171215
[Lr] Data última revisão:
171215
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171206
[St] Status:MEDLINE


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[PMID]:28760842
[Au] Autor:Murray T
[Ad] Endereço:Toronto, Ont.
[Ti] Título:Support grows for paying surrogates.
[So] Source:CMAJ;189(30):E1004-E1005, 2017 07 31.
[Is] ISSN:1488-2329
[Cp] País de publicação:Canada
[La] Idioma:eng
[Mh] Termos MeSH primário: Remuneração
Técnicas de Reprodução Assistida/legislação & jurisprudência
Mães Substitutas/legislação & jurisprudência
[Mh] Termos MeSH secundário: Canadá
Feminino
Seres Humanos
Gravidez
Técnicas de Reprodução Assistida/economia
Técnicas de Reprodução Assistida/ética
[Pt] Tipo de publicação:NEWS
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171102
[Lr] Data última revisão:
171102
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170802
[St] Status:MEDLINE
[do] DOI:10.1503/cmaj.1095444


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[PMID]:28347494
[Au] Autor:Ethics Committee of the American Society for Reproductive Medicine. Electronic address: ASRM@asrm.org; Ethics Committee of the American Society for Reproductive Medicine
[Ti] Título:Using family members as gamete donors or gestational carriers.
[So] Source:Fertil Steril;107(5):1136-1142, 2017 May.
[Is] ISSN:1556-5653
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The use of adult intrafamilial gamete donors and gestational surrogates is generally ethically acceptable when all participants are fully informed and counseled, but consanguineous arrangements or ones that simulate incestuous unions should be prohibited. Adult child-to-parent arrangements require caution in order to avoid coercion, and parent-to-adult child arrangements are acceptable in limited situations. Programs that choose to participate in intrafamilial arrangements should be prepared to spend additional time counseling participants and ensuring that they have made free, informed decisions. This document replaces the document of the same name, last published in 2012 (Fertil Steril 2012;98:797-803).
[Mh] Termos MeSH primário: Transtornos Cromossômicos/prevenção & controle
Família
Consentimento Livre e Esclarecido/ética
Inseminação Artificial Heteróloga/ética
Doação de Oócitos/ética
Mães Substitutas
[Mh] Termos MeSH secundário: Transtornos Cromossômicos/embriologia
Transtornos Cromossômicos/genética
Tomada de Decisão Clínica/ética
Consanguinidade
Feminino
Aconselhamento Genético/ética
Células Germinativas
Seres Humanos
Infertilidade/genética
Infertilidade/terapia
Doadores de Tecidos
Estados Unidos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170818
[Lr] Data última revisão:
170818
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170329
[St] Status:MEDLINE


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[PMID]:28333218
[Au] Autor:Blake L; Carone N; Raffanello E; Slutsky J; Ehrhardt AA; Golombok S
[Ad] Endereço:Centre for Family Research, University of Cambridge, Free School Lane, Cambridge, UK.
[Ti] Título:Gay fathers' motivations for and feelings about surrogacy as a path to parenthood.
[So] Source:Hum Reprod;32(4):860-867, 2017 04 01.
[Is] ISSN:1460-2350
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Study question: Why do gay men choose to start their families through surrogacy? Summary answer: Most fathers chose surrogacy because they considered adoption to be a less desirable and/or accessible path to parenthood. What is known already: Little is known of gay fathers' motivations to use surrogacy as a path to parenthood over and above other forms of family building, such as adoption, and no studies have examined fathers' satisfaction with the surrogacy process. Study design size, duration: This study used a cross-sectional design as part of a larger investigation of parent-child relationships and child adjustment in 40 gay father surrogacy families. Multiple strategies (e.g. surrogacy agencies, social events and snowballing) were used to recruit as diverse a sample as possible. Data were obtained from 74 fathers (in 6 families only 1 father was available for interview). Participants/materials, setting, method: Semi-structured interviews, lasting ~1 h, were conducted in the family home (65%) or over Skype (35%) with 74 gay fathers (35 genetic fathers, 32 non-genetic fathers and 7 fathers who did not know or did not disclose who the genetic father was), when the children were 3-9 years old. Main results and the role of chance: Genetic and non-genetic fathers were just as likely to want to become parents and had similar motivations for choosing surrogacy as a path to parenthood. Most fathers (N = 55, 74%) were satisfied with surrogacy and were satisfied (N = 31. 42%) or had neutral feelings (N = 21, 28%) about their choice of who would be the genetic father. Most fathers received supportive reactions to their decision to use surrogacy from both families of origin (e.g. parents, siblings) (N = 47, 64%) and from friends (N = 63, 85%). Limitations, reasons for caution: Although diverse recruitment strategies were used, data were obtained from a volunteer sample. Therefore, the possibility that fathers who had a positive surrogacy experience may have been more likely to participate in the study, and therefore introduce bias, cannot be ruled out. Due to the high average annual income of the fathers in the study, findings may not generalize to gay fathers with lower incomes. Wider implications of the findings: It is often assumed that parents' primary motivation for using ART is to have a genetic connection to the child. This study revealed that whilst genetic fatherhood was important for some gay fathers in surrogacy families, it was not important for all. This information will be of use to surrogacy agencies and organizations supporting men who are considering the different routes to parenthood. Study funding/competing interest(s): This work was funded by the Wellcome Trust [097857/Z/11/Z] and the Jacob's Foundation. None of the authors has any conflict of interest to declare. Trial registration number: N/A.
[Mh] Termos MeSH primário: Emoções
Pai/psicologia
Motivação
Minorias Sexuais e de Gênero/psicologia
Mães Substitutas/psicologia
[Mh] Termos MeSH secundário: Adulto
Seres Humanos
Masculino
Poder Familiar
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170324
[St] Status:MEDLINE
[do] DOI:10.1093/humrep/dex026


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[PMID]:28245820
[Au] Autor:Klitzman R
[Ad] Endereço:Columbia University, 1051 Riverside Drive #15, New York, NY, 10032, USA. rlk2@columbia.edu.
[Ti] Título:Unconventional combinations of prospective parents: ethical challenges faced by IVF providers.
[So] Source:BMC Med Ethics;18(1):18, 2017 Feb 28.
[Is] ISSN:1472-6939
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Professional guidelines have addressed ethical dilemmas posed by a few types of nontraditional procreative arrangements (e.g., gamete donations between family members), but many questions arise regarding how providers view and make decisions about these and other such arrangements. METHODS: Thirty-seven ART providers and 10 patients were interviewed in-depth for approximately 1 h each. Interviews were systematically analyzed. RESULTS: Providers faced a range of challenges and ethical dilemmas concerning both the content and the process of decisions about requests for unconventional interfamilial and other reproductive combinations. Providers vary in how they respond - what they decide, who exactly decides (e.g., an ethics committee or not), and how - often undergoing complex decision-making processes. These combinations can involve creating or raising the child, and can shift over time - from initial ART treatment through to the child's birth. Patients' requests can vary from fully established to mere possibilities. Arrangements may also be unstable, fluid, or unexpected, posing challenges. Difficulties emerge concerning not only familial but social, combinations (e.g., between friends). These arrangements can involve blurry and confusing roles, questions about the welfare of the unborn child, and unanticipated and unfamiliar questions about how to weigh competing moral and scientific concerns - e.g., the autonomy of the individuals involved, and the potential risks and benefits. Clinicians may feel that these requests do not "smell right"; and at first respond with feelings of "yuck," and only later, carefully and explicitly consider the ethical principles involved. Proposed arrangements may, for instance, initially be felt to involve consanguineous individuals, but not in fact do so. Obtaining and verifying full and appropriate informed consent can be difficult, given implicit familial and/or cultural expectations and senses of duty. Social attitudes are changing, yet patients' views of these issues may also vary, based on their cultural backgrounds. CONCLUSIONS: These data, the first to examine how clinicians make decisions about unconventional reproductive arrangements, highlight several critical ethical questions and ambiguities, and variations in clinicians' responses. While several professional guidelines exist, the current data highlight additional challenges, and have vital implications for improving future guidelines, practice, education and research. TRIAL REGISTRATION: Not applicable.
[Mh] Termos MeSH primário: Atitude do Pessoal de Saúde
Temas Bioéticos
Doação Dirigida de Tecido
Família
Fertilização In Vitro/ética
Pessoal de Saúde/ética
Mães Substitutas
[Mh] Termos MeSH secundário: Criança
Tomada de Decisões
Relações Familiares
Feminino
Seres Humanos
Consentimento Livre e Esclarecido
Masculino
Princípios Morais
Pais
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171004
[Lr] Data última revisão:
171004
[Sb] Subgrupo de revista:E; IM
[Da] Data de entrada para processamento:170302
[St] Status:MEDLINE
[do] DOI:10.1186/s12910-017-0177-x


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[PMID]:28073959
[Au] Autor:Mazur LJ; Kisthardt MK; Kim HH; Rosas LM; Lantos JD
[Ad] Endereço:University of Texas Health Sciences Center, Houston, Texas.
[Ti] Título:Surrogate Pregnancy After Prenatal Diagnosis of Spina Bifida.
[So] Source:Pediatrics;139(2), 2017 Feb.
[Is] ISSN:1098-4275
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Some pregnancies today involve infertile individuals or couples who contract with a fertile woman to carry a pregnancy for them. The woman who carries the pregnancy is referred to as a "gestational carrier." The use of such arrangements is increasing. Most of the time, these arrangements play out as planned; sometimes, however, problems arise. This article discusses a case in which a fetal diagnosis of spina bifida led the infertile couple to request that the gestational carrier terminate the pregnancy, and the gestational carrier did not wish to do so. Experts in the medical and legal issues surrounding surrogacy discuss the considerations that should go into resolving such a conflict.
[Mh] Termos MeSH primário: Aborto Eugênico/legislação & jurisprudência
Contratos/legislação & jurisprudência
Disrafismo Espinal/diagnóstico
Mães Substitutas/legislação & jurisprudência
Ultrassonografia Pré-Natal
[Mh] Termos MeSH secundário: Adulto
Feminino
Fertilização In Vitro/legislação & jurisprudência
Seres Humanos
Recém-Nascido
Infertilidade
Masculino
Negociação
Gravidez
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170627
[Lr] Data última revisão:
170627
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170112
[St] Status:MEDLINE


  8 / 1575 MEDLINE  
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Registro de Ensaios Clínicos
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[PMID]:28069560
[Au] Autor:Graham ML; Strawderman MS; Demment M; Olson CM
[Ad] Endereço:Division of Nutritional Sciences, Cornell University, Ithaca, NY, United States.
[Ti] Título:Does Usage of an eHealth Intervention Reduce the Risk of Excessive Gestational Weight Gain? Secondary Analysis From a Randomized Controlled Trial.
[So] Source:J Med Internet Res;19(1):e6, 2017 Jan 09.
[Is] ISSN:1438-8871
[Cp] País de publicação:Canada
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Excessive gestational weight gain (GWG) contributes to the development of obesity in mother and child. Internet-based interventions have the potential for delivering innovative and interactive options for prevention of excessive GWG to large numbers of people. OBJECTIVE: The objective of this study was to create a novel measure of Internet-based intervention usage patterns and examine whether usage of an Internet-based intervention is associated with reduced risk of excessive GWG. METHODS: The website featured blogs, local resources, articles, frequently asked questions (FAQs), and events that were available to women in both the intervention and control arm. Weekly reminders to use the website and to highlight new content were emailed to participants in both arms. Only intervention arm participants had access to the weight gain tracker and diet and physical activity goal-setting tools. A total of 1335 (898 intervention and 437 control) relatively diverse and healthy pregnant women were randomly assigned to the intervention arm or control arm. Usage patterns were examined for both intervention and control arm participants using latent class analysis. Regression analyses were used to estimate the association between usage patterns and three GWG outcomes: excessive total GWG, excessive GWG rate, and GWG. RESULTS: Five usage patterns best characterized the usage of the intervention by intervention arm participants. Three usage patterns best characterized control arm participants' usage. Control arm usage patterns were not associated with excessive GWG, whereas intervention arm usage patterns were associated with excessive GWG. CONCLUSIONS: The control and intervention arm usage pattern characterization is a unique methodological contribution to process evaluations for self-directed Internet-based interventions. In the intervention arm some usage patterns were associated with GWG outcomes. CLINICALTRIAL: ClinicalTrials.gov; Clinical Trials Number: NCT01331564; https://clinicaltrials.gov/ct2/show/NCT01331564 (Archived by WebCite at http://www.webcitation/6nI9LuX9w).
[Mh] Termos MeSH primário: Internet
Obesidade/prevenção & controle
Complicações na Gravidez/prevenção & controle
Telemedicina
Ganho de Peso/fisiologia
[Mh] Termos MeSH secundário: Adulto
Exercício
Feminino
Seres Humanos
Gravidez
Risco
Mães Substitutas
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170811
[Lr] Data última revisão:
170811
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170111
[Cl] Clinical Trial:ClinicalTrial
[St] Status:MEDLINE
[do] DOI:10.2196/jmir.6644


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[PMID]:28069181
[Au] Autor:Practice Committee of the American Society for Reproductive Medicine and Practice Committee of the Society for Assisted Reproductive Technology. Electronic address: ASRM@asrm.org; Practice Committee of the American Society for Reproductive Medicine and Practice Committee of the Society for Assisted Reproductive Technology
[Ti] Título:Recommendations for practices utilizing gestational carriers: a committee opinion.
[So] Source:Fertil Steril;107(2):e3-e10, 2017 Feb.
[Is] ISSN:1556-5653
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:This document provides the latest recommendations for evaluation of gestational carriers and intended parents. It incorporates recent information from the US Centers for Disease Control and Prevention, the US Food and Drug Administration, and the American Association of Tissue Banks, with which all programs offering gestational carrier services must be thoroughly familiar. This document replaces the previous document of the same name, last published in 2015 (Fertil Steril 2015; 103:e1-8).
[Mh] Termos MeSH primário: Comitês Consultivos/normas
Nível de Saúde
Infertilidade/terapia
Saúde Mental/normas
Pais/psicologia
Técnicas de Reprodução Assistida/normas
Mães Substitutas/psicologia
[Mh] Termos MeSH secundário: Comitês Consultivos/legislação & jurisprudência
Feminino
Fertilidade
Política de Saúde
Seres Humanos
Infertilidade/diagnóstico
Infertilidade/fisiopatologia
Saúde Mental/legislação & jurisprudência
Formulação de Políticas
Gravidez
Técnicas de Reprodução Assistida/utilização
Doenças Sexualmente Transmissíveis/diagnóstico
Mães Substitutas/legislação & jurisprudência
[Pt] Tipo de publicação:JOURNAL ARTICLE; PRACTICE GUIDELINE
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170613
[Lr] Data última revisão:
170613
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170111
[St] Status:MEDLINE


  10 / 1575 MEDLINE  
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[PMID]:27839744
[Au] Autor:Carone N; Baiocco R; Lingiardi V
[Ad] Endereço:Department of Developmental and Social Psychology, Faculty of Medicine and Psychology, Sapienza University of Rome, via dei Marsi 78, 00185, Rome, Italy. Electronic address: nicola.carone@uniroma1.it.
[Ti] Título:Italian gay fathers' experiences of transnational surrogacy and their relationship with the surrogate pre- and post-birth.
[So] Source:Reprod Biomed Online;34(2):181-190, 2017 Feb.
[Is] ISSN:1472-6491
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:This study aims to explore the experience of transnational surrogacy and the relationship with the surrogate pre- and post-birth in Italian gay father families. Couple and individual semi-structured interviews were carried out with 30 Italian gay partnered fathers with at least one child born through gestational surrogacy in California or Canada. No couples had known their surrogates or egg donors previously. The Interpretative Phenomenological Analysis indicated that three interrelated themes could be helpful for understanding the gay fathers' experience of their geographical distance from the surrogate: the perceived loss of control over the pregnancy; the surrogate as a person who facilitates the fathers' feelings of being emotionally connected to their developing child; the surrogate as an 'aunty' who, along with her family, maintains a relationship with the fathers. None of the fathers mentioned the egg donor during the interview. The study inspires reflections in offshore fertility practitioners on how pre- and ongoing surrogacy counselling for prospective gay fathers should be tailored. It further calls for the necessity of offering psychological counselling in gay fathers' resident countries in order to promote informed decisions before starting surrogacy abroad and to elaborate on potential difficulties related to surrogacy after the child's birth.
[Mh] Termos MeSH primário: Pai/psicologia
Homossexualidade Masculina/psicologia
Doação de Oócitos
Mães Substitutas/psicologia
[Mh] Termos MeSH secundário: California
Canadá
Feminino
Geografia
Seres Humanos
Internacionalidade
Itália
Masculino
Gravidez
Inquéritos e Questionários
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161115
[St] Status:MEDLINE



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