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  1 / 19306 MEDLINE  
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[PMID]:29444081
[Au] Autor:Arakaki X; Shoga M; Li L; Zouridakis G; Tran T; Fonteh AN; Dawlaty J; Goldweber R; Pogoda JM; Harrington MG
[Ad] Endereço:Neurosciences, Huntington Medical Research Institutes, Pasadena, California, United States of America.
[Ti] Título:Alpha desynchronization/synchronization during working memory testing is compromised in acute mild traumatic brain injury (mTBI).
[So] Source:PLoS One;13(2):e0188101, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Diagnosing and monitoring recovery of patients with mild traumatic brain injury (mTBI) is challenging because of the lack of objective, quantitative measures. Diagnosis is based on description of injuries often not witnessed, subtle neurocognitive symptoms, and neuropsychological testing. Since working memory (WM) is at the center of cognitive functions impaired in mTBI, this study was designed to define objective quantitative electroencephalographic (qEEG) measures of WM processing that may correlate with cognitive changes associated with acute mTBI. First-time mTBI patients and mild peripheral (limb) trauma controls without head injury were recruited from the emergency department. WM was assessed by a continuous performance task (N-back). EEG recordings were obtained during N-back testing on three occasions: within five days, two weeks, and one month after injury. Compared with controls, mTBI patients showed abnormal induced and evoked alpha activity including event-related desynchronization (ERD) and synchronization (ERS). For induced alpha power, TBI patients had excessive frontal ERD on their first and third visit. For evoked alpha, mTBI patients had lower parietal ERD/ERS at the second and third visits. These exploratory qEEG findings offer new and non-invasive candidate measures to characterize the evolution of injury over the first month, with potential to provide much-needed objective measures of brain dysfunction to diagnose and monitor the consequences of mTBI.
[Mh] Termos MeSH primário: Lesões Encefálicas Traumáticas/fisiopatologia
Memória de Curto Prazo
[Mh] Termos MeSH secundário: Doença Aguda
Adulto
Eletroencefalografia
Feminino
Seres Humanos
Masculino
Índice de Gravidade de Doença
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180215
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0188101


  2 / 19306 MEDLINE  
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[PMID]:27777275
[Au] Autor:Tamborello FP; Trafton JG
[Ad] Endereço:Cogscent, LLC, Houston, TX.
[Ti] Título:Human Error as an Emergent Property of Action Selection and Task Place-Holding.
[So] Source:Hum Factors;59(3):377-392, 2017 05.
[Is] ISSN:1547-8181
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: A computational process model could explain how the dynamic interaction of human cognitive mechanisms produces each of multiple error types. BACKGROUND: With increasing capability and complexity of technological systems, the potential severity of consequences of human error is magnified. Interruption greatly increases people's error rates, as does the presence of other information to maintain in an active state. METHOD: The model executed as a software-instantiated Monte Carlo simulation. It drew on theoretical constructs such as associative spreading activation for prospective memory, explicit rehearsal strategies as a deliberate cognitive operation to aid retrospective memory, and decay. RESULTS: The model replicated the 30% effect of interruptions on postcompletion error in Ratwani and Trafton's Stock Trader task, the 45% interaction effect on postcompletion error of working memory capacity and working memory load from Byrne and Bovair's Phaser Task, as well as the 5% perseveration and 3% omission effects of interruption from the UNRAVEL Task. CONCLUSION: Error classes including perseveration, omission, and postcompletion error fall naturally out of the theory. APPLICATION: The model explains post-interruption error in terms of task state representation and priming for recall of subsequent steps. Its performance suggests that task environments providing more cues to current task state will mitigate error caused by interruption. For example, interfaces could provide labeled progress indicators or facilities for operators to quickly write notes about their task states when interrupted.
[Mh] Termos MeSH primário: Cognição
Simulação por Computador
Memória de Curto Prazo
Análise e Desempenho de Tarefas
[Mh] Termos MeSH secundário: Seres Humanos
Internet
Software
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, U.S. GOV'T, NON-P.H.S.
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM; S
[Da] Data de entrada para processamento:161026
[St] Status:MEDLINE
[do] DOI:10.1177/0018720816672529


  3 / 19306 MEDLINE  
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[PMID]:29374153
[Au] Autor:Lundqvist M; Herman P; Warden MR; Brincat SL; Miller EK
[Ad] Endereço:The Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, 43 Vassar Street, Cambridge, MA, 02139, USA. lundqvis@mit.edu.
[Ti] Título:Gamma and beta bursts during working memory readout suggest roles in its volitional control.
[So] Source:Nat Commun;9(1):394, 2018 01 26.
[Is] ISSN:2041-1723
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Working memory (WM) activity is not as stationary or sustained as previously thought. There are brief bursts of gamma (~50-120 Hz) and beta (~20-35 Hz) oscillations, the former linked to stimulus information in spiking. We examined these dynamics in relation to readout and control mechanisms of WM. Monkeys held sequences of two objects in WM to match to subsequent sequences. Changes in beta and gamma bursting suggested their distinct roles. In anticipation of having to use an object for the match decision, there was an increase in gamma and spiking information about that object and reduced beta bursting. This readout signal was only seen before relevant test objects, and was related to premotor activity. When the objects were no longer needed, beta increased and gamma decreased together with object spiking information. Deviations from these dynamics predicted behavioral errors. Thus, beta could regulate gamma and the information in WM.
[Mh] Termos MeSH primário: Ritmo beta/fisiologia
Ritmo Gama/fisiologia
Memória de Curto Prazo/fisiologia
Reconhecimento Visual de Modelos/fisiologia
Córtex Pré-Frontal/fisiologia
[Mh] Termos MeSH secundário: Animais
Feminino
Macaca mulatta
Masculino
Estimulação Luminosa
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180227
[Lr] Data última revisão:
180227
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180128
[St] Status:MEDLINE
[do] DOI:10.1038/s41467-017-02791-8


  4 / 19306 MEDLINE  
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[PMID]:29314866
[Au] Autor:Herrlinger KA; Nieman KM; Sanoshy KD; Fonseca BA; Lasrado JA; Schild AL; Maki KC; Wesnes KA; Ceddia MA
[Ad] Endereço:1 Kemin Foods, LC , Des Moines, IA.
[Ti] Título:Spearmint Extract Improves Working Memory in Men and Women with Age-Associated Memory Impairment.
[So] Source:J Altern Complement Med;24(1):37-47, 2018 Jan.
[Is] ISSN:1557-7708
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: The purpose of this study was to investigate the effects of supplementation with a spearmint (Mentha spicata L.) extract, high in polyphenols including rosmarinic acid, on cognitive performance, sleep, and mood in individuals with age-associated memory impairment (AAMI). DESIGN: Subjects with AAMI (N = 90; 67% female; age = 59.4 ± 0.6 years) were randomly assigned (n = 30/group) to consume 900, 600, or 0 mg/day (two capsules, once daily) spearmint extract for 90 days, in this double-blind, placebo-controlled trial. Assessments were completed for cognition (days 0, 45, and 90), sleep (days 0 and 90), and mood (days 0 and 90) by using the Cognitive Drug Research (CDR) System , Leeds Sleep Evaluation Questionnaire (LSEQ), and Profile of Mood States (POMS ), respectively. RESULTS: Quality of working memory and spatial working memory accuracy improved after supplementation with 900 mg/day spearmint extract by 15% (p = 0.0469) and 9% (p = 0.0456), respectively, versus placebo. Subjects consuming 900 mg/day spearmint extract reported improvement in their ability to fall asleep, relative to subjects consuming placebo (p = 0.0046). Overall treatment effects were evident for vigor-activity (p = 0.0399), total mood disturbance (p = 0.0374), and alertness and behavior following wakefulness (p = 0.0415), with trends observed for improvements after spearmint supplementation relative to placebo. CONCLUSIONS: These results suggest that the distinct spearmint extract may be a beneficial nutritional intervention for cognitive health in older subjects with AAMI.
[Mh] Termos MeSH primário: Transtornos da Memória/tratamento farmacológico
Memória de Curto Prazo/efeitos dos fármacos
Extratos Vegetais/farmacologia
Extratos Vegetais/uso terapêutico
[Mh] Termos MeSH secundário: Cinamatos
Cognição/efeitos dos fármacos
Depsídeos
Feminino
Seres Humanos
Masculino
Mentha spicata
Meia-Idade
Polifenóis
Sono/efeitos dos fármacos
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Cinnamates); 0 (Depsides); 0 (Plant Extracts); 0 (Polyphenols); MQE6XG29YI (rosmarinic acid)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180223
[Lr] Data última revisão:
180223
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180110
[St] Status:MEDLINE
[do] DOI:10.1089/acm.2016.0379


  5 / 19306 MEDLINE  
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[PMID]:29251972
[Au] Autor:Hutsell BA; Banks ML
[Ad] Endereço:Department of Pharmacology and Toxicology, Virginia Commonwealth University.
[Ti] Título:Remifentanil maintains lower initial delayed nonmatching-to-sample accuracy compared to food pellets in male rhesus monkeys.
[So] Source:Exp Clin Psychopharmacol;25(6):441-447, 2017 12.
[Is] ISSN:1936-2293
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Emerging human laboratory and preclinical drug self-administration data suggest that a history of contingent abused drug exposure impairs performance in operant discrimination procedures, such as delayed nonmatching-to-sample (DNMTS), that are hypothesized to assess components of executive function. However, these preclinical discrimination studies have exclusively used food as the reinforcer and the effects of drugs as reinforcers in these operant procedures are unknown. The present study determined effects of contingent intravenous remifentanil injections on DNMTS performance hypothesized to assess 1 aspect of executive function, working memory. Daily behavioral sessions consisted of 2 components with sequential intravenous remifentanil (0, 0.01-1.0 µg/kg/injection) or food (0, 1-10 pellets) availability in nonopioid dependent male rhesus monkeys (n = 3). Remifentanil functioned as a reinforcer in the DNMTS procedure. Similar delay-dependent DNMTS accuracy was observed under both remifentanil- and food-maintained components, such that higher accuracies were maintained at shorter (0.1-1.0 s) delays and lower accuracies approaching chance performance were maintained at longer (10-32 s) delays. Remifentanil maintained significantly lower initial DNMTS accuracy compared to food. Reinforcer magnitude was not an important determinant of DNMTS accuracy for either remifentanil or food. These results extend the range of experimental procedures under which drugs function as reinforcers. Furthermore, the selective remifentanil-induced decrease in initial DNMTS accuracy is consistent with a selective impairment of attentional, but not memorial, processes. (PsycINFO Database Record
[Mh] Termos MeSH primário: Anestésicos Intravenosos/administração & dosagem
Condicionamento Operante/efeitos dos fármacos
Desvalorização pelo Atraso/efeitos dos fármacos
Discriminação (Psicologia)/efeitos dos fármacos
Piperidinas/administração & dosagem
Esquema de Reforço
[Mh] Termos MeSH secundário: Animais
Relação Dose-Resposta a Droga
Função Executiva/efeitos dos fármacos
Alimentos
Macaca mulatta
Masculino
Memória de Curto Prazo/efeitos dos fármacos
Fatores de Tempo
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL
[Nm] Nome de substância:
0 (Anesthetics, Intravenous); 0 (Piperidines); P10582JYYK (remifentanil)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180224
[Lr] Data última revisão:
180224
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171219
[St] Status:MEDLINE
[do] DOI:10.1037/pha0000154


  6 / 19306 MEDLINE  
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[PMID]:28459277
[Au] Autor:Swanson HL
[Ad] Endereço:University of California.
[Ti] Título:Verbal and visual-spatial working memory: What develops over a life span?
[So] Source:Dev Psychol;53(5):971-995, 2017 May.
[Is] ISSN:1939-0599
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:This study investigates whether age-related changes in the structure of 5 complex working memory (WM) tasks (a) reflect a general or domain specific system, (b) follows a similar trajectory across different age spans, and (c) contribute domain general or domain specific resources to achievement measures. The study parsed the sample (N = 2,471) into 11 age groups (mean ages of 6, 7, 8, 9, 11, 13, 15, 18, 26, 41, and 66 years), and compared their performances on verbal and visuospatial WM measures. Three important findings emerged: (a) a confirmatory factor analysis and Schmid-Leiman transformation to a high-order model solution supported a domain general factor model for the total sample as well as separately for children and adults, (b) performance on visual-spatial WM tasks as a function of age decreased at a faster rate than verbal WM tasks, and (c) both verbal and visual-spatial WM measures in concert with each other uniquely predicted reading and math measures, suggesting that a domain general WM system contributed to performance on achievement measures. The results support the notion that (a) complex WM tasks function as a domain general system and (b) the factor structure for children and adults on complex WM tasks was highly similar, even though there was evidence of differentiation among verbal and visual-spatial WM measures at certain age groups. (PsycINFO Database Record
[Mh] Termos MeSH primário: Desenvolvimento Humano/fisiologia
Memória de Curto Prazo/fisiologia
Reconhecimento Visual de Modelos/fisiologia
Percepção Espacial/fisiologia
Percepção da Fala/fisiologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Fatores Etários
Idoso
Idoso de 80 Anos ou mais
Criança
Pré-Escolar
Feminino
Seres Humanos
Masculino
Meia-Idade
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180222
[Lr] Data última revisão:
180222
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170502
[St] Status:MEDLINE
[do] DOI:10.1037/dev0000291


  7 / 19306 MEDLINE  
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[PMID]:28470554
[Au] Autor:Adam KCS; Vogel EK
[Ad] Endereço:Department of Psychology, University of Chicago, 5848 S. University Ave., Chicago, IL, 60637, USA. kadam1@uchicago.edu.
[Ti] Título:Confident failures: Lapses of working memory reveal a metacognitive blind spot.
[So] Source:Atten Percept Psychophys;79(5):1506-1523, 2017 Jul.
[Is] ISSN:1943-393X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Working memory performance fluctuates dramatically from trial to trial. On many trials, performance is no better than chance. Here, we assessed participants' awareness of working memory failures. We used a whole-report visual working memory task to quantify both trial-by-trial performance and trial-by-trial subjective ratings of inattention to the task. In Experiment 1 (N = 41), participants were probed for task-unrelated thoughts immediately following 20% of trials. In Experiment 2 (N = 30), participants gave a rating of their attentional state following 25% of trials. Finally, in Experiments 3a (N = 44) and 3b (N = 34), participants reported confidence of every response using a simple mouse-click judgment. Attention-state ratings and off-task thoughts predicted the number of items correctly identified on each trial, replicating previous findings that subjective measures of attention state predict working memory performance. However, participants correctly identified failures on only around 28% of failure trials. Across experiments, participants' metacognitive judgments reliably predicted variation in working memory performance but consistently and severely underestimated the extent of failures. Further, individual differences in metacognitive accuracy correlated with overall working memory performance, suggesting that metacognitive monitoring may be key to working memory success.
[Mh] Termos MeSH primário: Atenção/fisiologia
Julgamento/fisiologia
Memória de Curto Prazo/fisiologia
Metacognição/fisiologia
Estimulação Luminosa/métodos
[Mh] Termos MeSH secundário: Conscientização/fisiologia
Feminino
Seres Humanos
Individualidade
Masculino
Distribuição Aleatória
Pensamento/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180220
[Lr] Data última revisão:
180220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170505
[St] Status:MEDLINE
[do] DOI:10.3758/s13414-017-1331-8


  8 / 19306 MEDLINE  
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[PMID]:28462484
[Au] Autor:Edwards KS; Shin M
[Ad] Endereço:School of Psychology, Charles Sturt University, Bathurst, New South Wales, Australia.
[Ti] Título:Media multitasking and implicit learning.
[So] Source:Atten Percept Psychophys;79(5):1535-1549, 2017 Jul.
[Is] ISSN:1943-393X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Media multitasking refers to the simultaneous use of different forms of media. Previous research comparing heavy media multitaskers and light media multitaskers suggests that heavy media multitaskers have a broader scope of attention. The present study explored whether these differences in attentional scope would lead to a greater degree of implicit learning for heavy media multitaskers. The study also examined whether media multitasking behaviour is associated with differences in visual working memory, and whether visual working memory differentially affects the ability to process contextual information. In addition to comparing extreme groups (heavy and light media multitaskers) the study included analysis of people who media multitask in moderation (intermediate media multitaskers). Ninety-four participants were divided into groups based on responses to the media use questionnaire, and completed the contextual cueing and n-back tasks. Results indicated that the speed at which implicit learning occurred was slower in heavy media multitaskers relative to both light and intermediate media multitaskers. There was no relationship between working memory performance and media multitasking group, and no relationship between working memory and implicit learning. There was also no evidence for superior performance of intermediate media multitaskers. A deficit in implicit learning observed in heavy media multitaskers is consistent with previous literature, which suggests that heavy media multitaskers perform more poorly than light media multitaskers in attentional tasks due to their wider attentional scope.
[Mh] Termos MeSH primário: Meios de Comunicação
Sinais (Psicologia)
Aprendizagem/fisiologia
Comportamento Multitarefa/fisiologia
Estimulação Luminosa/métodos
[Mh] Termos MeSH secundário: Adolescente
Adulto
Atenção/fisiologia
Cognição/fisiologia
Feminino
Seres Humanos
Masculino
Memória de Curto Prazo/fisiologia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180220
[Lr] Data última revisão:
180220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170503
[St] Status:MEDLINE
[do] DOI:10.3758/s13414-017-1319-4


  9 / 19306 MEDLINE  
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[PMID]:29079513
[Au] Autor:Vann SD
[Ad] Endereço:School of Psychology, Cardiff University, 70 Park Place, Cardiff, CF10 3AT, UK. Electronic address: vannsd@cardiff.ac.uk.
[Ti] Título:Lesions within the head direction system reduce retrosplenial c-fos expression but do not impair performance on a radial-arm maze task.
[So] Source:Behav Brain Res;338:153-158, 2018 Feb 15.
[Is] ISSN:1872-7549
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:The lateral mammillary nuclei are a central structure within the head direction system yet there is still relatively little known about how these nuclei contribute to spatial performance. In the present study, rats with selective neurotoxic lesions of the lateral mammillary nuclei were tested on a working memory task in a radial-arm maze. This task requires animals to distinguish between eight radially-oriented arms and remember which arms they have entered within a session. Even though it might have been predicted that this task would heavily tax the head direction system, the lesion rats performed equivalently to their surgical controls on this task; no deficit emerged even when the task was made more difficult by rotating the maze mid-way through testing in order to reduce reliance on intramaze cues. Rats were subsequently tested in the dark to increase the use of internally generated direction cues but the lesion rats remained unimpaired. In contrast, the lateral mammillary nuclei lesions were found to decrease retrosplenial c-Fos levels. These results would suggest that the head direction system is not required for the acquisition of the standard radial-arm maze task. It would also suggest that small decreases in retrosplenial c-Fos are not sufficient to produce behavioural impairments.
[Mh] Termos MeSH primário: Comportamento Animal/fisiologia
Corpos Mamilares/fisiopatologia
Proteínas Proto-Oncogênicas c-fos/metabolismo
Comportamento Espacial/fisiologia
Memória Espacial/fisiologia
[Mh] Termos MeSH secundário: Animais
Comportamento Animal/efeitos dos fármacos
Ácido Ibotênico/toxicidade
Masculino
Corpos Mamilares/efeitos dos fármacos
Memória de Curto Prazo/efeitos dos fármacos
Memória de Curto Prazo/fisiologia
Ratos
Comportamento Espacial/efeitos dos fármacos
Memória Espacial/efeitos dos fármacos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Proto-Oncogene Proteins c-fos); 2552-55-8 (Ibotenic Acid)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180216
[Lr] Data última revisão:
180216
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171029
[St] Status:MEDLINE


  10 / 19306 MEDLINE  
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[PMID]:28460315
[Au] Autor:Davis MT; DellaGioia N; Matuskey D; Harel B; Maruff P; Pietrzak RH; Esterlis I
[Ad] Endereço:Yale University School of Medicine, Departments of Psychiatry and Diagnostic Radiology, USA. Electronic address: margaret.t.davis@yale.edu.
[Ti] Título:Preliminary evidence concerning the pattern and magnitude of cognitive dysfunction in major depressive disorder using cogstate measures.
[So] Source:J Affect Disord;218:82-85, 2017 Aug 15.
[Is] ISSN:1573-2517
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Cognitive deficits are common in individuals with major depressive disorder (MDD), and are associated with treatment non-responsiveness and poorer functional outcomes. Characterization of the nature and magnitude of deficits in this population has been limited in part by lack of brief, practical, and well-validated assessment measures. The goal of this study was to use a brief, practical, and repeatable computerized cognitive test battery from Cogstate to examine differences in cognitive functioning between individuals with MDD and healthy controls. METHODS: Forty participants (22 healthy controls (HCs), 18 with MDD) completed a battery of six cognitive measures, as well as measures of intellectual functioning (intellect) and depressive symptom severity. A multivariate analysis of covariance (MANCOVA) was conducted to compare cognitive test performance across groups while controlling for intellect. RESULTS: Individuals with MDD had lower full-scale IQ scores on average, and performed worse on measures of visual attention (d=1.04), verbal learning (d=1.22) and memory (d=1.22), and visuospatial problem solving (d=0.80) than HCs after adjustment for differences in intellect. Psychomotor speed, visual memory, and working memory did not differ between groups. CONCLUSIONS: Cogstate measures appear to be sensitive in assessing deficits in attention, verbal learning and memory, and executive function in individuals with MDD. Further research will be useful in establishing the utility of Cogstate measures for standard use in research and clinical practice.
[Mh] Termos MeSH primário: Disfunção Cognitiva/diagnóstico
Transtorno Depressivo Maior/psicologia
Testes Neuropsicológicos
[Mh] Termos MeSH secundário: Adulto
Atenção
Estudos de Casos e Controles
Cognição
Disfunção Cognitiva/psicologia
Função Executiva
Feminino
Seres Humanos
Masculino
Memória de Curto Prazo
Meia-Idade
Análise Multivariada
Resolução de Problemas
Reprodutibilidade dos Testes
Sensibilidade e Especificidade
Aprendizagem Verbal
[Pt] Tipo de publicação:EVALUATION STUDIES; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180214
[Lr] Data última revisão:
180214
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170502
[St] Status:MEDLINE



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BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde