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[PMID]: 28410087 [Au] Autor: Natale JE; Lebet R; Joseph JG; Ulysse C; Ascenzi J; Wypij D; Curley MAQ; Randomized Evaluation of Sedation Titration for Respiratory Failure (RESTORE) Study Investigators [Ad] Endereço: Department of Pediatrics, University of California, Davis, CA. Electronic address: jenatale@ucdavis.edu. [Ti] Título: Racial and Ethnic Disparities in Parental Refusal of Consent in a Large, Multisite Pediatric Critical Care Clinical Trial. [So] Source: J Pediatr;184:204-208.e1, 2017 May. [Is] ISSN: 1097-6833 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: OBJECTIVE: To evaluate whether race or ethnicity was independently associated with parental refusal of consent for their child's participation in a multisite pediatric critical care clinical trial. STUDY DESIGN: We performed a secondary analyses of data from Randomized Evaluation of Sedation Titration for Respiratory Failure (RESTORE), a 31-center cluster randomized trial of sedation management in critically ill children with acute respiratory failure supported on mechanical ventilation. Multivariable logistic regression modeling estimated associations between patient race and ethnicity and parental refusal of study consent. RESULT: Among the 3438 children meeting enrollment criteria and approached for consent, 2954 had documented race/ethnicity of non-Hispanic White (White), non-Hispanic Black (Black), or Hispanic of any race. Inability to approach for consent was more common for parents of Black (19.5%) compared with White (11.7%) or Hispanic children (13.2%). Among those offered consent, parents of Black (29.5%) and Hispanic children (25.9%) more frequently refused consent than parents of White children (18.2%, P < .0167 for each). Compared with parents of White children, parents of Black (OR 2.15, 95% CI 1.56-2.95, P < .001) and Hispanic (OR 1.44, 95% CI 1.10-1.88, P = .01) children were more likely to refuse consent. Parents of children offered participation in the intervention arm were more likely to refuse consent than parents in the control arm (OR 2.15, 95% CI 1.37-3.36, P < .001). CONCLUSIONS: Parents of Black and Hispanic children were less likely to be approached for, and more frequently declined consent for, their child's participation in a multisite critical care clinical trial. Ameliorating this racial disparity may improve the validity and generalizability of study findings. TRIAL REGISTRATION: ClinicalTrials.gov: NCT00814099. [Mh] Termos MeSH primário: Afroamericanos Cuidados Críticos Grupo com Ancestrais do Continente Europeu Hispano-Americanos Pais Recusa de Participação [Mh] Termos MeSH secundário: Criança Pré-Escolar Feminino Seres Humanos Lactente Masculino [Pt] Tipo de publicação: COMPARATIVE STUDY; JOURNAL ARTICLE; MULTICENTER STUDY; RANDOMIZED CONTROLLED TRIAL [Em] Mês de entrada: 1708 [Cu] Atualização por classe: 170810 [Lr] Data última revisão: 170810 [Sb] Subgrupo de revista: AIM; IM [Da] Data de entrada para processamento: 170415 [St] Status: MEDLINE

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[PMID]: 28148221 [Au] Autor: Akmatov MK; Jentsch L; Riese P; May M; Ahmed MW; Werner D; Rösel A; Prokein J; Bernemann I; Klopp N; Prochnow B; Illig T; Schindler C; Guzman CA; Pessler F [Ad] Endereço: TWINCORE, Centre for Experimental and Clinical Infection Research, Hannover, Germany. manas.akmatov@twincore.de. [Ti] Título: Motivations for (non)participation in population-based health studies among the elderly - comparison of participants and nonparticipants of a prospective study on influenza vaccination. [So] Source: BMC Med Res Methodol;17(1):18, 2017 Feb 02. [Is] ISSN: 1471-2288 [Cp] País de publicação: England [La] Idioma: eng [Ab] Resumo: BACKGROUND: Participation in epidemiological studies has strongly declined in recent years. We examined the reasons for (non)participation in population-based health studies among participants and nonparticipants of a prospective study on influenza vaccination among the elderly. METHODS: Males and females between 65 and 80 years of age (N = 5582) were randomly selected from the residents' registration office in Hannover, Germany, and were invited to participate in a study featuring vaccination with a seasonal adjuvanted influenza vaccine (Fluad™, Novartis) including five follow-up visits (day 0, 1/3, 7, 21, 70 with respect to vaccination). A 24-item nonresponder questionnaire, including 10 items on reasons for participating in a hypothetical health study, was mailed to 1500 randomly selected nonparticipants. The same 10 items were included in the end-of-study questionnaire administered to the participants in the vaccination study (n = 200). Logistic regression analysis with backward elimination was used to identify the reasons most strongly associated with nonparticipation. RESULTS: Five hundred thirty-one (35%) nonparticipants and 200 participants (100%) returned the respective questionnaires. Nonparticipation was associated with a lower interest in obtaining personal health information (OR = 3.32) and a preference for less invasive (OR = 3.01) and less time-demanding (OR = 2.19) studies. Responses to other items, e.g. regarding altruistic motives, monetary compensation, general interest of the study, or study approval through ethics committee and data security authority, did not differ between participants and nonparticipants. CONCLUSIONS: Participation rates in health studies among elderly individuals could potentially be improved by reducing interventions and time demand, for instance by implementing methods of self-sampling and remote data collection. TRIAL REGISTRATION: No. 1100359 (ClinicalTrials.gov, date of registration: 09.02.2015). [Mh] Termos MeSH primário: Inquéritos Epidemiológicos Vacinas contra Influenza/uso terapêutico Influenza Humana/prevenção & controle Cooperação do Paciente/psicologia Recusa de Participação/psicologia Vacinação/estatística & dados numéricos [Mh] Termos MeSH secundário: Idoso Feminino Alemanha Seres Humanos Masculino Motivação Estudos Prospectivos [Pt] Tipo de publicação: COMPARATIVE STUDY; JOURNAL ARTICLE [Nm] Nome de substância: 0 (Influenza Vaccines) [Em] Mês de entrada: 1710 [Cu] Atualização por classe: 171031 [Lr] Data última revisão: 171031 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170203 [St] Status: MEDLINE [do] DOI: 10.1186/s12874-017-0302-z

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[PMID]: 27854538 [Au] Autor: Parasidis E; Opel DJ [Ad] Endereço: Efthimios Parasidis is with the Moritz College of Law and the College of Public Health, The Ohio State University, Columbus. Douglas J. Opel is with the Department of Pediatrics, University of Washington School of Medicine, and Treuman Katz Center for Pediatric Bioethics, Seattle Children's Hospital, Seattle. [Ti] Título: Parental Refusal of Childhood Vaccines and Medical Neglect Laws. [So] Source: Am J Public Health;107(1):68-71, 2017 Jan. [Is] ISSN: 1541-0048 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: OBJECTIVES: To examine the relation of vaccine refusal and medical neglect under child welfare laws. METHODS: We used the Westlaw legal database to search court opinions from 1905 to 2016 and identified cases in which vaccine refusal was the sole or a primary reason in a neglect proceeding. We also delineated if religious or philosophical exemptions from required school immunizations were available at the time of adjudication. RESULTS: Our search yielded 9 cases from 5 states. Most courts (7 of 9) considered vaccine refusal to constitute neglect. In the 4 cases decided in jurisdictions that permitted religious exemptions, courts either found that vaccine refusal did not constitute neglect or considered it neglect only in the absence of a sincere religious objection to vaccination. CONCLUSIONS: Some states have a legal precedent for considering parental vaccine refusal as medical neglect, but this is based on a small number of cases. Each state should clarify whether, under its laws, vaccine refusal constitutes medical neglect. [Mh] Termos MeSH primário: Bem-Estar da Criança/ética Bem-Estar da Criança/legislação & jurisprudência Pais/psicologia Recusa de Participação/ética Recusa de Participação/legislação & jurisprudência Religião e Medicina Vacinação/ética Vacinação/legislação & jurisprudência [Mh] Termos MeSH secundário: Criança Feminino Seres Humanos Imunidade Coletiva Programas de Imunização Masculino Saúde Pública Política Pública Instituições Acadêmicas Estados Unidos [Pt] Tipo de publicação: JOURNAL ARTICLE; REVIEW [Em] Mês de entrada: 1706 [Cu] Atualização por classe: 170612 [Lr] Data última revisão: 170612 [Sb] Subgrupo de revista: AIM; IM [Da] Data de entrada para processamento: 161118 [St] Status: MEDLINE

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[PMID]: 27854520 [Au] Autor: Brennan JM; Bednarczyk RA; Richards JL; Allen KE; Warraich GJ; Omer SB [Ad] Endereço: Julia M. Brennan, Jennifer L. Richards, Gohar J. Warraich, and Saad B. Omer are with the Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA. Robert A. Bednarczyk and Kristen E. Allen are with Hubert Department of Global Health, Rollins School of Public Health. [Ti] Título: Trends in Personal Belief Exemption Rates Among Alternative Private Schools: Waldorf, Montessori, and Holistic Kindergartens in California, 2000-2014. [So] Source: Am J Public Health;107(1):108-112, 2017 Jan. [Is] ISSN: 1541-0048 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: OBJECTIVES: To evaluate trends in rates of personal belief exemptions (PBEs) to immunization requirements for private kindergartens in California that practice alternative educational methods. METHODS: We used California Department of Public Health data on kindergarten PBE rates from 2000 to 2014 to compare annual average increases in PBE rates between schools. RESULTS: Alternative schools had an average PBE rate of 8.7%, compared with 2.1% among public schools. Waldorf schools had the highest average PBE rate of 45.1%, which was 19 times higher than in public schools (incidence rate ratio = 19.1; 95% confidence interval = 16.4, 22.2). Montessori and holistic schools had the highest average annual increases in PBE rates, slightly higher than Waldorf schools (Montessori: 8.8%; holistic: 7.1%; Waldorf: 3.6%). CONCLUSIONS: Waldorf schools had exceptionally high average PBE rates, and Montessori and holistic schools had higher annual increases in PBE rates. Children in these schools may be at higher risk for spreading vaccine-preventable diseases if trends are not reversed. [Mh] Termos MeSH primário: Pais/psicologia Recusa de Participação/estatística & dados numéricos Instituições Acadêmicas Vacinação/tendências [Mh] Termos MeSH secundário: California Criança Pré-Escolar Cultura Seres Humanos Setor Privado Religião e Medicina [Pt] Tipo de publicação: JOURNAL ARTICLE [Em] Mês de entrada: 1706 [Cu] Atualização por classe: 170612 [Lr] Data última revisão: 170612 [Sb] Subgrupo de revista: AIM; IM [Da] Data de entrada para processamento: 161118 [St] Status: MEDLINE

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[PMID]: 27059857 [Au] Autor: Teuber A; Sundermann B; Kugel H; Schwindt W; Heindel W; Minnerup J; Dannlowski U; Berger K; Wersching H [Ad] Endereço: Institute of Epidemiology and Social Medicine, University of Münster, Albert-Schweitzer-Campus 1, 48149, Münster, Germany. anja.teuber@uni-muenster.de. [Ti] Título: MR imaging of the brain in large cohort studies: feasibility report of the population- and patient-based BiDirect study. [So] Source: Eur Radiol;27(1):231-238, 2017 Jan. [Is] ISSN: 1432-1084 [Cp] País de publicação: Germany [La] Idioma: eng [Ab] Resumo: OBJECTIVES: To describe the implementation and protocol of cerebral magnetic resonance imaging (MRI) in the longitudinal BiDirect study and to report rates of study participation as well as management of incidental findings. METHODS: Data came from the BiDirect study that investigates the relationship between depression and arteriosclerosis and comprises 2258 participants in three cohorts: 999 patients with depression, 347 patients with manifest cardiovascular disease (CVD) and 912 population-based controls. The study program includes MRI of the brain. Reasons for non-participation were systematically collected. Incidental findings were categorized and disclosed according to clinical relevance. RESULTS: At baseline 2176 participants were offered MRI, of whom 1453 (67 %) completed it. Reasons for non-participation differed according to cohort, age and gender with controls showing the highest participation rate of 79 %. Patient cohorts had higher refusal rates and CVD patients a high prevalence of contraindications. In the first follow-up examination 69 % of participating subjects completed MRI. Incidental findings were disclosed to 246 participants (17 %). The majority of incidental findings were extensive white matter hyperintensities requiring further diagnostic work-up. CONCLUSIONS: Knowledge about subjects and sensible definition of incidental findings are crucial for large-scale imaging projects. Our data offer practical and concrete information for the design of future studies. KEY POINTS: • Willingness to participate in MRI is generally high, also in follow-up examinations. • Rates of refusal and prevalence of contraindications differ according to subject characteristics. • Extensive white matter hyperintensities considerably increase the disclosure rates of incidental findings. • MRI workflow requires continuous case-by-case handling by an interdisciplinary team. [Mh] Termos MeSH primário: Encéfalo/diagnóstico por imagem Transtorno Depressivo Maior/diagnóstico por imagem Arteriosclerose Intracraniana/diagnóstico por imagem Imagem por Ressonância Magnética/métodos [Mh] Termos MeSH secundário: Adulto Idoso Encéfalo/patologia Estudos de Casos e Controles Estudos de Coortes Contraindicações Transtorno Depressivo Maior/epidemiologia Estudos de Viabilidade Feminino Alemanha/epidemiologia Seres Humanos Achados Incidentais Arteriosclerose Intracraniana/epidemiologia Estudos Longitudinais Masculino Meia-Idade Prevalência Recusa de Participação Fatores Sexuais Revelação da Verdade [Pt] Tipo de publicação: JOURNAL ARTICLE; MULTICENTER STUDY [Em] Mês de entrada: 1701 [Cu] Atualização por classe: 171116 [Lr] Data última revisão: 171116 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 160410 [St] Status: MEDLINE

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[PMID]: 27742308 [Au] Autor: Czerwinski J; Malanowski P; Kosieradzki M; Jonas M; Jakubowska-Winecka A [Ad] Endereço: Department of Surgical and Transplant Nursing, Medical University of Warsaw, Warsaw, Poland; Polish Transplant Coordinating Center (Poltransplant), Warsaw, Poland. Electronic address: jczerwinski@poltransplant.pl. [Ti] Título: Relationships Between Social Attitudes Toward Deceased Organ Donation and the Donation Rates in Poland, a Country With an Opting-out System. [So] Source: Transplant Proc;48(7):2399-2402, 2016 Sep. [Is] ISSN: 1873-2623 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: BACKGROUND: Monitoring of attitudes toward deceased donation gives the general view of the acceptance of this treatment but does not allow for precise prediction of single person's behavior. Consistency of actions and attitudes has many determinants, personal and situational. The idea of this study was to assess and compare relationships between behaviors and attitudes toward postmortem organ donation in single districts and between larger regions of the country (west and east). METHODS: Indicators calculated for the years 1996-2014 included the number of potential deceased donors (per million population [pmp]/y), the number of objections registered in the refusal registry (pmp), and the number and percentage of family refusals to donation. To assess relationships between variables, statistical and descriptive analyses were used. RESULTS: There were 10,731 potential donor referrals: 10 times more in the most active than in the least active province. Potential donor referrals from the western region were almost twice as high (18.3 pmp/y) as from the east (10.1). In 1,045 cases (9.7%), organs were not used owing to objections of the relatives; this index differed in each province up to 7-fold, but was almost the same in western and eastern regions. Total number of objections listed in the Refusal Registry was 28,725 (748 pmp). This index was different in each district up to 4-fold, but was not distinctly different in west and east regions. No distinct correlation (Pearson test) was found among the 3 assessed variables. CONCLUSIONS: Donation in Poland has much geographic differences. There is no common pattern of behavior and attitude toward donation and no correlation between these variables. [Mh] Termos MeSH primário: Atitude Frente à Saúde/etnologia Opinião Pública Recusa de Participação Sistema de Registros Obtenção de Tecidos e Órgãos/estatística & dados numéricos [Mh] Termos MeSH secundário: Seres Humanos Polônia Doadores de Tecidos [Pt] Tipo de publicação: JOURNAL ARTICLE [Em] Mês de entrada: 1704 [Cu] Atualização por classe: 170817 [Lr] Data última revisão: 170817 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 161016 [St] Status: MEDLINE

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[PMID]: 27496400 [Au] Autor: Malanowski P; Antoszkiewicz K; Jakubowska-Winecka A; Czerwinski J; Danielewicz R [Ad] Endereço: Polish Transplant Coordinating Center Poltransplant, Warsaw, Poland. Electronic address: pmalanowski@poltransplant.pl. [Ti] Título: Central Register of Objections for Deceased Donation in Poland 1996 to 2014: The Country With an Opting-Out System. [So] Source: Transplant Proc;48(5):1337-40, 2016 Jun. [Is] ISSN: 1873-2623 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: BACKGROUND: Organ, tissue, and cell procurement from deceased donors for transplantation requires consent and authorization, documented donor's positive acceptance, or lack of objection to donation expressed while alive (consent). It also requires the fulfillment of other legal conditions required by law, such as person's legal abilities to act in this field or to obtain approval for donation (authorization). Consent to and authorization of donation from deceased donors requires regulations at the national level. Poland developed an opting-out policy with the Transplantation Act in 1996. The Central Register of Objections (CRO) was introduced on November 1, 1996. The purpose of this article is a formal analysis of all submitted objections and objection withdrawals managed by the CRO since the introduction of the registry in 1996 until the end of 2014. MATERIALS AND METHODS: All data collected by the CRO during 18 years of service was subject to analysis. The objections and withdrawals of objections are summarized in the tables, along with the age, sex, and place of residence of the registered residents. RESULTS: By December 31, 2014, a total of 29,288 records were registered, including 29,013 registered objections and 275 registered withdrawals of objections; this means that 0.075% of the country's population expressed objection to posthumous tissue and organ donation for transplantation. Legal representatives submitted 4208 declarations (15.6% of all declarations). The largest inflow of objections took place in 1997, the first full year of CRO activity. CONCLUSION: CRO is an indispensable option in a country with opt-out system as a part of organ donation authorization protocol. Number of registered objections is extremely low, in practice, this leads to a situation where the will of the deceased most often is obtained from his family. [Mh] Termos MeSH primário: Comportamento de Escolha Recusa de Participação/estatística & dados numéricos Sistema de Registros Obtenção de Tecidos e Órgãos/estatística & dados numéricos [Mh] Termos MeSH secundário: Morte Seres Humanos Polônia Doadores de Tecidos/estatística & dados numéricos [Pt] Tipo de publicação: JOURNAL ARTICLE [Em] Mês de entrada: 1704 [Cu] Atualização por classe: 170817 [Lr] Data última revisão: 170817 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 160807 [St] Status: MEDLINE

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[PMID]: 27453375 [Au] Autor: Robson SM; Bolling C; McCullough MB; Stough CO; Stark LJ [Ad] Endereço: Department of Behavioral Health and Nutrition, University of Delaware, Newark, DE; Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH. [Ti] Título: A Preschool Obesity Treatment Clinical Trial: Reasons Primary Care Providers Declined Referrals. [So] Source: J Pediatr;177:262-266.e1, 2016 Oct. [Is] ISSN: 1097-6833 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: OBJECTIVE: To examine referral by primary care providers (PCPs) of preschool children with obesity (≥95th percentile for body mass index [BMI]) to a weight management intervention when offered through a randomized clinical trial (RCT), and identify reasons for not referring children. STUDY DESIGN: In phase I, 3 experts in obesity, psychology, and nutrition completed an open card sort and classified PCPs' reasons for declining referral into groups based on similarity of reasons. Categories were then defined and labeled. In phase II, 2 independent sorters placed each decline into 1 of the categories defined in phase I. RESULTS: PCPs referred 78% of eligible children to the RCT. Compared with children declined for referral, referred children had a significantly higher weight (48.4 lb vs 46.1 lb; P < .001) and BMI percentile (97.6 vs 97.0; P < .001). Eleven categories for decline were identified in phase I. In phase II, excellent reliability was obtained between each independent sorter and the phase I categories, and also between the 2 independent sorters (κ values, 0.72-1.0). The most common reason for declining was "family not a good fit" (23.6%), followed by "doesn't believe weight is a problem" (13.9%), "family would not be interested" (12%), and "doesn't believe measurement is accurate" (11.5%). Appropriately, exclusionary criteria of the RCT was a reason as well (11.8%). CONCLUSION: The availability of weight management for preschoolers through RCTs appeared to overcome barriers of resources, time, and credible treatment cited in previous studies. However, concerns about the family's response or interest in a weight management program remained barriers, as did PCPs' perceptions about obesity in young children. TRIAL REGISTRATION: ClinicalTrials.gov:NCT01546727. [Mh] Termos MeSH primário: Obesidade Pediátrica/terapia Atenção Primária à Saúde Encaminhamento e Consulta Recusa de Participação [Mh] Termos MeSH secundário: Pré-Escolar Feminino Seres Humanos Masculino Meia-Idade [Pt] Tipo de publicação: JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL [Em] Mês de entrada: 1706 [Cu] Atualização por classe: 171001 [Lr] Data última revisão: 171001 [Sb] Subgrupo de revista: AIM; IM [Da] Data de entrada para processamento: 160726 [Cl] Clinical Trial: ClinicalTrial [St] Status: MEDLINE

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[PMID]: 27268454 [Au] Autor: Capol S [Ad] Endereço: 1 Sanacare Gruppenpraxis Paulusplatz, Luzern. [Ti] Título: [Understanding and Handling Vaccine Hesitancy]. [Ti] Título: Schaudern vor Impfzaudern?. [So] Source: Ther Umsch;73(5):291-6, 2016. [Is] ISSN: 0040-5930 [Cp] País de publicação: Switzerland [La] Idioma: ger [Ab] Resumo: Vaccine hesitancy is a growing concern to experts around the world and could increasingly jeopardize the success of vaccination campaigns. Ambivalence in questions of vaccination is promoted through mistrust of vaccines and providers, furthermore through the plethora of unfiltered and often contradictory information leading to uncertainty as to whom one shall believe. Individuals are also in a dilemma in issues of vaccination, having to decide if they will accept vaccines regarding only their own wellbeing or also as an act of solidarity to maintain a high level of vaccination rates in order to eradicate diseases. Finally vaccine hesitancy is also maintained by the success of vaccination. Vaccine preventable diseases have become so seldom that many individuals perceive them as negligible. The risk of vaccination then surpasses the risk of disease thus leading to the rejection of vaccination. Although those opposing vaccination comprise only a small minority of the population, their arguments seem to be heard disproportionately, influencing vaccine hesitants very strongly. On the other hand family doctors are still highly appreciated as advisors in health related issues. These health providers can play an important role in stimulating vaccine acceptance. Delivering transparent and evidence-based information on vaccination through competent communication skills helps to rebuild the dwindling trust in vaccines. Sufficient time is required for an enriching dialogue. [Mh] Termos MeSH primário: Recusa de Participação/psicologia Vacinação/psicologia [Mh] Termos MeSH secundário: Medicina Baseada em Evidências Medicina Geral Educação em Saúde Seres Humanos Programas de Imunização Suíça Confiança Incerteza [Pt] Tipo de publicação: ENGLISH ABSTRACT; JOURNAL ARTICLE; REVIEW [Em] Mês de entrada: 1608 [Cu] Atualização por classe: 160609 [Lr] Data última revisão: 160609 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 160609 [St] Status: MEDLINE [do] DOI: 10.1024/0040-5930/a000794

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[PMID]: 27188061 [Au] Autor: Nau JY [Ti] Título: [Not Available]. [Ti] Título: MISCELLANÉES RÉCRÉATIVES ET VIROLOGIQUES, PHARMACEUTIQUES ET CATHOLIQUES.. [So] Source: Rev Med Suisse;12(511):622-3, 2016 Mar 23. [Is] ISSN: 1660-9379 [Cp] País de publicação: Switzerland [La] Idioma: fre [Mh] Termos MeSH primário: Anticoncepcionais Vacinas contra Hepatite B/efeitos adversos Microcefalia/virologia Esclerose Múltipla Farmacêuticos/ética Recusa de Participação/ética Infecção pelo Zika virus/complicações [Mh] Termos MeSH secundário: Consciência Feminino Seres Humanos Gravidez Transtornos Relacionados ao Uso de Substâncias Zika virus [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Contraceptive Agents); 0 (Hepatitis B Vaccines) [Em] Mês de entrada: 1606 [Cu] Atualização por classe: 160518 [Lr] Data última revisão: 160518 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 160519 [St] Status: MEDLINE

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