Base de dados : MEDLINE
Pesquisa : F02.830.816.964.186.624 [Categoria DeCS]
Referências encontradas : 9 [refinar]
Mostrando: 1 .. 9   no formato [Detalhado]

página 1 de 1

  1 / 9 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:26974946
[Au] Autor:Hathibelagal AR; Feigl B; Kremers J; Zele AJ
[Ti] Título:Correlated and uncorrelated invisible temporal white noise alters mesopic rod signaling.
[So] Source:J Opt Soc Am A Opt Image Sci Vis;33(3):A93-103, 2016 Mar.
[Is] ISSN:1520-8532
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:We determined how rod signaling at mesopic light levels is altered by extrinsic temporal white noise that is correlated or uncorrelated with the activity of one (magnocellular, parvocellular, or koniocellular) postreceptoral pathway. Rod and cone photoreceptor excitations were independently controlled using a four-primary photostimulator. Psychometric (Weibull) functions were measured for incremental rod pulses (50 to 250 ms) in the presence (or absence; control) of perceptually invisible subthreshold extrinsic noise. Uncorrelated (rod) noise facilitates rod detection. Correlated postreceptoral pathway noise produces differential changes in rod detection thresholds and decreases the slope of the psychometric functions. We demonstrate that invisible extrinsic noise changes rod-signaling characteristics within the three retinogeniculate pathways at mesopic illumination depending on the temporal profile of the rod stimulus and the extrinsic noise type.
[Mh] Termos MeSH primário: Luz
Células Fotorreceptoras Retinianas Bastonetes/citologia
Células Fotorreceptoras Retinianas Bastonetes/efeitos da radiação
Transdução de Sinais
[Mh] Termos MeSH secundário: Adulto
Seres Humanos
Masculino
Modelos Biológicos
Psicometria
Interação Cone-Bastonete/efeitos da radiação
Fatores de Tempo
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1612
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160315
[St] Status:MEDLINE
[do] DOI:10.1364/JOSAA.33.000A93


  2 / 9 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
PubMed Central Texto completo
Texto completo
[PMID]:26352594
[Au] Autor:Newkirk GS; Hoon M; Wong RO; Detwiler PB
[Ad] Endereço:Department of Physiology & Biophysics and Program in Neurobiology & Behavior, University of Washington, Seattle, Washington, United States of America.
[Ti] Título:Response Properties of a Newly Identified Tristratified Narrow Field Amacrine Cell in the Mouse Retina.
[So] Source:PLoS One;10(9):e0137702, 2015.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Amacrine cells were targeted for whole cell recording using two-photon fluorescence microscopy in a transgenic mouse line in which the promoter for dopamine receptor 2 drove expression of green fluorescent protein in a narrow field tristratified amacrine cell (TNAC) that had not been studied previously. Light evoked a multiphasic response that was the sum of hyperpolarizing and depolarization synaptic inputs consistent with distinct dendritic ramifications in the off and on sublamina of the inner plexiform layer. The amplitude and waveform of the response, which consisted of an initial brief hyperpolarization at light onset followed by recovery to a plateau potential close to dark resting potential and a hyperpolarizing response at the light offset varied little over an intensity range from 0.4 to ~10^6 Rh*/rod/s. This suggests that the cell functions as a differentiator that generates an output signal (a transient reduction in inhibitory input to downstream retina neurons) that is proportional to the derivative of light input independent of its intensity. The underlying circuitry appears to consist of rod and cone driven on and off bipolar cells that provide direct excitatory input to the cell as well as to GABAergic amacrine cells that are synaptically coupled to TNAC. Canonical reagents that blocked excitatory (glutamatergic) and inhibitory (GABA and glycine) synaptic transmission had effects on responses to scotopic stimuli consistent with the rod driven component of the proposed circuit. However, responses evoked by photopic stimuli were paradoxical and could not be interpreted on the basis of conventional thinking about the neuropharmacology of synaptic interactions in the retina.
[Mh] Termos MeSH primário: Células Amácrinas/metabolismo
Neurônios GABAérgicos/metabolismo
Receptores Dopaminérgicos/metabolismo
Retina/metabolismo
[Mh] Termos MeSH secundário: Células Amácrinas/patologia
Animais
Neurônios GABAérgicos/patologia
Glicina/metabolismo
Luz
Camundongos
Camundongos Transgênicos
Microscopia de Fluorescência por Excitação Multifotônica
Receptores Dopaminérgicos/genética
Retina/patologia
Interação Cone-Bastonete/genética
Transmissão Sináptica/genética
Ácido gama-Aminobutírico/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Receptors, Dopamine); 56-12-2 (gamma-Aminobutyric Acid); TE7660XO1C (Glycine)
[Em] Mês de entrada:1606
[Cu] Atualização por classe:170119
[Lr] Data última revisão:
170119
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150910
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0137702


  3 / 9 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
PubMed Central Texto completo
Texto completo
[PMID]:24695205
[Au] Autor:Zele AJ; Maynard ML; Joyce DS; Cao D
[Ti] Título:Effect of rod-cone interactions on mesopic visual performance mediated by chromatic and luminance pathways.
[So] Source:J Opt Soc Am A Opt Image Sci Vis;31(4):A7-A14, 2014 Apr 01.
[Is] ISSN:1520-8532
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:We studied the effect of rod-cone interactions on mesopic visual reaction time (RT). Rod and cone photoreceptor excitations were independently controlled using a four-primary photostimulator. It was observed that (1) lateral rod-cone interactions increase the cone-mediated RTs; (2) the rod-cone interactions are strongest when rod sensitivity is maximal in a dark surround, but weaker with increased rod activity in a light surround; and (3) the presence of a dark surround nonselectively increased the mean and variability of chromatic (+L-M, S-cone) and luminance (L+M+S) RTs independent of the level of rod activity. The results demonstrate that lateral rod-cone interactions must be considered when deriving mesopic luminous efficiency using RT.
[Mh] Termos MeSH primário: Percepção de Cores/fisiologia
Interação Cone-Bastonete/fisiologia
[Mh] Termos MeSH secundário: Seres Humanos
Psicofísica
Tempo de Reação
Células Fotorreceptoras Retinianas Cones/citologia
Células Fotorreceptoras Retinianas Bastonetes/citologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1412
[Cu] Atualização por classe:161019
[Lr] Data última revisão:
161019
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140404
[St] Status:MEDLINE
[do] DOI:10.1364/JOSAA.31.0000A7


  4 / 9 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:23325348
[Au] Autor:Zele AJ; Maynard ML; Feigl B
[Ad] Endereço:Institute of Health and Biomedical Innovation and School of Optometry and Vision Science, Queensland University of Technology, Brisbane, Australia. andrew.zele@qut.edu.au
[Ti] Título:Rod and cone pathway signaling and interaction under mesopic illumination.
[So] Source:J Vis;13(1), 2013 Jan 16.
[Is] ISSN:1534-7362
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:This study investigates the time-course and post-receptoral pathway signaling of photoreceptor interactions when the rod (R) and three cone (L, M, S) photoreceptor classes contribute to mesopic vision. A four-primary photostimulator independently controls photoreceptor activity in human observers. The first experiment defines the temporal adaptation response of receptoral (L-, S-cone, rod) and post-receptoral (LMS, LMSR, +L-M) signaling and interactions. Here we show that nonopponent cone-cone interactions (L-cone, LMS, LMSR) have monophasic temporal response patterns whereas opponent signals (+L-M, S-cone) show biphasic response patterns with slower recovery. By comparison, rod-cone interactions with nonopponent signals have faster adaptation responses and reduced sensitivity loss whereas opponent rod-cone interactions are small or absent. Additionally, the rod-rod interaction differs from these interaction types and acts to increase rod sensitivity due to temporal summation but with a slower time course. The second experiment shows that the temporal profile of the rod signal alters the relative rod contributions to the three primary post-receptoral pathways. We demonstrate that rod signals generate luminance (+L+M) signals mediated via the MC pathway with all rod temporal profiles and chromatic signals (L/L+M, S/L+M) in both the PC and KC pathways with durations >75 ms. Thus, we propose that the change in relative weighting of rod signals within the post-receptoral pathways contributes to the sensitivity and temporal response of rod and cone pathway signaling and interactions.
[Mh] Termos MeSH primário: Sensibilidades de Contraste/fisiologia
Visão Mesópica/fisiologia
Estimulação Luminosa/métodos
Células Fotorreceptoras Retinianas Cones/fisiologia
Células Fotorreceptoras Retinianas Bastonetes/fisiologia
Interação Cone-Bastonete/fisiologia
[Mh] Termos MeSH secundário: Adulto
Comunicação Celular
Percepção de Cores/fisiologia
Feminino
Seres Humanos
Luz
Transdução de Sinais
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1306
[Cu] Atualização por classe:130117
[Lr] Data última revisão:
130117
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:130118
[St] Status:MEDLINE


  5 / 9 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:22330378
[Au] Autor:Zele AJ; Kremers J; Feigl B
[Ad] Endereço:Visual Science Laboratory, School of Optometry and Vision Science & Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia. andrew.zele@qut.edu.au
[Ti] Título:Mesopic rod and S-cone interactions revealed by modulation thresholds.
[So] Source:J Opt Soc Am A Opt Image Sci Vis;29(2):A19-26, 2012 Feb 01.
[Is] ISSN:1520-8532
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:We analyzed mesopic rod and S-cone interactions in terms of their contributions to the blue-yellow opponent pathway. Stimuli were generated using a four-primary colorimeter. Mixed rod and S-cone modulation thresholds (constant L-, M-cone excitation) were measured as a function of their phase difference. Modulation amplitude was equated using threshold units and contrast ratios. This study identified three interaction types: (1) a linear and antagonistic rod:S-cone interaction, (2) probability summation, and (3) a previously unidentified mutual nonlinear reinforcement. Linear rod:S-cone interactions occur within the blue-yellow opponent pathway. Probability summation involves signaling by different postreceptoral pathways. The origin of the nonlinear reinforcement is possibly at the photoreceptors.
[Mh] Termos MeSH primário: Células Fotorreceptoras Retinianas Cones/citologia
Células Fotorreceptoras Retinianas Bastonetes/citologia
Interação Cone-Bastonete
[Mh] Termos MeSH secundário: Cor
Colorimetria
Seres Humanos
Estimulação Luminosa
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1206
[Cu] Atualização por classe:120214
[Lr] Data última revisão:
120214
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:120215
[St] Status:MEDLINE
[do] DOI:10.1364/JOSAA.29.000A19


  6 / 9 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:22068599
[Au] Autor:Seeliger MW; Brombas A; Weiler R; Humphries P; Knop G; Tanimoto N; Müller F
[Ad] Endereço:Division of Ocular Neurodegeneration, Institute for Ophthalmic Research, Centre for Ophthalmology, Eberhard Karls University of Tübingen, Schleichstr. 4/3, D-72076 Tübingen, Germany. see@uni-tuebingen.de
[Ti] Título:Modulation of rod photoreceptor output by HCN1 channels is essential for regular mesopic cone vision.
[So] Source:Nat Commun;2:532, 2011 Nov 08.
[Is] ISSN:2041-1723
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Retinal photoreceptors permit visual perception over a wide range of lighting conditions. Rods work best in dim, and cones in bright environments, with considerable functional overlap at intermediate (mesopic) light levels. At many sites in the outer and inner retina where rod and cone signals interact, gap junctions, particularly those containing Connexin36, have been identified. However, little is known about the dynamic processes associated with the convergence of rod and cone system signals into ON- and OFF-pathways. Here we show that proper cone vision under mesopic conditions requires rapid adaptational feedback modulation of rod output via hyperpolarization-activated and cyclic nucleotide-gated channels 1. When these channels are absent, sustained rod responses following bright light exposure saturate the retinal network, resulting in a loss of downstream cone signalling. By specific genetic and pharmacological ablation of key signal processing components, regular cone signalling can be restored, thereby identifying the sites involved in functional rod-cone interactions.
[Mh] Termos MeSH primário: Canais de Cátion Regulados por Nucleotídeos Cíclicos/metabolismo
Canais de Potássio/metabolismo
Células Fotorreceptoras Retinianas Cones/metabolismo
Células Fotorreceptoras Retinianas Bastonetes/metabolismo
Interação Cone-Bastonete/fisiologia
[Mh] Termos MeSH secundário: Animais
Canais de Cátion Regulados por Nucleotídeos Cíclicos/genética
Eletrofisiologia
Eletrorretinografia
Canais Disparados por Nucleotídeos Cíclicos Ativados por Hiperpolarização
Técnicas In Vitro
Camundongos
Camundongos Knockout
Canais de Potássio/genética
Retina/metabolismo
Retina/fisiologia
Interação Cone-Bastonete/genética
Transdução de Sinais/genética
Transdução de Sinais/fisiologia
Visão Ocular/genética
Visão Ocular/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Cyclic Nucleotide-Gated Cation Channels); 0 (Hcn1 protein, mouse); 0 (Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels); 0 (Potassium Channels)
[Em] Mês de entrada:1205
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:111110
[St] Status:MEDLINE
[do] DOI:10.1038/ncomms1540


  7 / 9 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
PubMed Central Texto completo
Texto completo
[PMID]:21350569
[Au] Autor:De Salvo G; Hogg C; Holder GE; Lotery AJ
[Ti] Título:Enhanced rod-cone interaction with progressive macular dysfunction.
[So] Source:Eye (Lond);25(6):823-5, 2011 Jun.
[Is] ISSN:1476-5454
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Degeneração Macular/fisiopatologia
Interação Cone-Bastonete/fisiologia
[Mh] Termos MeSH secundário: Adaptação Ocular/fisiologia
Eletrorretinografia
Seres Humanos
Degeneração Macular/diagnóstico
Masculino
Acuidade Visual/fisiologia
Adulto Jovem
[Pt] Tipo de publicação:CASE REPORTS; LETTER
[Em] Mês de entrada:1109
[Cu] Atualização por classe:150204
[Lr] Data última revisão:
150204
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:110226
[St] Status:MEDLINE
[do] DOI:10.1038/eye.2011.27


  8 / 9 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
PubMed Central Texto completo
Texto completo
[PMID]:18561973
[Au] Autor:Cao D; Pokorny J; Smith VC; Zele AJ
[Ad] Endereço:Department of Ophthalmology & Visual Science, University of Chicago, 940 East 57th Street, Chicago, IL 60637, USA. d-cao@uchicago.edu
[Ti] Título:Rod contributions to color perception: linear with rod contrast.
[So] Source:Vision Res;48(26):2586-92, 2008 Nov.
[Is] ISSN:1878-5646
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:At mesopic light levels, an incremental change in rod activation causes changes in color appearance. In this study, we investigated how rod mediated changes in color perception varied as a function of the magnitude of the rod contrast. Rod-mediated changes in color appearance were assessed by matching them with cone-mediated color changes. A two-channel four-primary colorimeter allowed independent control of the rods and each of the L-, M- and S-cone photoreceptor types. At all light levels, rod contributions to inferred PC, KC and MC pathway mediated vision were linearly related to the rod incremental contrast. This linear relationship could be described by a model based on primate ganglion cell responses with the assumption that rod signals were conveyed via rod-cone gap junctions at mesopic light levels.
[Mh] Termos MeSH primário: Percepção de Cores/fisiologia
Células Fotorreceptoras Retinianas Bastonetes/fisiologia
[Mh] Termos MeSH secundário: Adaptação à Escuridão/fisiologia
Seres Humanos
Modelos Neurológicos
Modelos Psicológicos
Estimulação Luminosa/métodos
Psicofísica
Células Fotorreceptoras Retinianas Cones/fisiologia
Células Ganglionares da Retina/fisiologia
Interação Cone-Bastonete/fisiologia
Vias Visuais/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:0901
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:080620
[St] Status:MEDLINE
[do] DOI:10.1016/j.visres.2008.05.001


  9 / 9 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
PubMed Central Texto completo
Texto completo
[PMID]:18486960
[Au] Autor:Zele AJ; Cao D; Pokorny J
[Ad] Endereço:School of Optometry and The Institute of Health and Biomedical Innovation, Queensland University of Technology, 60 Musk Avenue, Brisbane, Qld 4059, Australia. andrew.zele@qut.edu.au
[Ti] Título:Rod-cone interactions and the temporal impulse response of the cone pathway.
[So] Source:Vision Res;48(26):2593-8, 2008 Nov.
[Is] ISSN:1878-5646
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Dark-adapted rods suppress cone-mediated flicker detection. This study evaluates the effect that rod activity has on cone temporal processing by investigating whether rod mediated suppression changes the cone pathway impulse response function, regardless of the form of the temporal signal. Stimuli were generated with a 2-channel photostimulator that has four primaries for the central field and four primaries for the surround. Cone pathway temporal impulse response functions were derived from temporal contrast sensitivity data with periodic stimuli, and from two-pulse discrimination data in which pairs of briefly pulsed stimuli were presented successively at a series of stimulus onset asynchronies. Dark-adapted rods altered the amplitude and timing of cone pathway temporal impulse response functions, irrespective of whether they were derived from measurements with temporally periodic stimuli or in a brief presentation temporal resolution task with pulsed stimuli. Rod-cone interactions are a fundamental operation in visual temporal processing under mesopic light levels, acting to decrease the temporal bandwidth of the visual system.
[Mh] Termos MeSH primário: Células Fotorreceptoras Retinianas Cones/fisiologia
Interação Cone-Bastonete/fisiologia
[Mh] Termos MeSH secundário: Sensibilidades de Contraste/fisiologia
Adaptação à Escuridão/fisiologia
Discriminação (Psicologia)/fisiologia
Seres Humanos
Masculino
Estimulação Luminosa/métodos
Psicofísica
Vias Visuais/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:0901
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:080520
[St] Status:MEDLINE
[do] DOI:10.1016/j.visres.2008.04.003



página 1 de 1
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde