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[PMID]:27771970
[Au] Autor:O'Donnell ML; Alkemade N; Creamer M; McFarlane AC; Silove D; Bryant RA; Felmingham K; Steel Z; Forbes D
[Ad] Endereço:From the Phoenix Australia Centre for Posttraumatic Mental Health, Carlton, Victoria, Australia; the Department of Psychiatry, University of Melbourne, Parkville, Victoria, Australia; the School of Psychology, University of New South Wales, Sydney, New South Wales, Australia; the School of Psychiatr
[Ti] Título:A Longitudinal Study of Adjustment Disorder After Trauma Exposure.
[So] Source:Am J Psychiatry;173(12):1231-1238, 2016 Dec 01.
[Is] ISSN:1535-7228
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: Adjustment disorder has been recategorized as a trauma- and stressor-related disorder in DSM-5. The aim of this study was to determine the prevalence of adjustment disorder in the first 12 months after severe injury; to determine whether adjustment disorder was a less severe disorder compared with other disorders in terms of disability and quality of life; to investigate the trajectory of adjustment disorder; and to examine whether the subtypes described in DSM-5 are distinguishable. METHOD: In a multisite, cohort study, injury patients were assessed during hospitalization and at 3 and 12 months postinjury (N=826). Structured clinical interviews were used to assess affective, anxiety, and substance use disorders, and self-report measures of disability, anxiety, depression, and quality of life were administered. RESULTS: The prevalence of adjustment disorder was 19% at 3 months and 16% at 12 months. Participants with adjustment disorder reported worse outcomes relative to those with no psychiatric diagnosis but better outcomes compared with those diagnosed with other psychiatric disorders. Participants with adjustment disorder at 3 months postinjury were significantly more likely to meet criteria for a psychiatric disorder at 12 months (odds ratio=2.67, 95% CI=1.59-4.49). Latent-profile analysis identified a three-class model that was based on symptom severity, not the subtypes identified by DSM-5. CONCLUSIONS: Recategorization of adjustment disorder into the trauma- and stressor-related disorders is supported by this study. However, further description of the phenomenology of the disorder is required.
[Mh] Termos MeSH primário: Transtornos de Adaptação/diagnóstico
Transtornos de Adaptação/epidemiologia
Ferimentos e Lesões/psicologia
[Mh] Termos MeSH secundário: Transtornos de Adaptação/psicologia
Adulto
Austrália/epidemiologia
Manual Diagnóstico e Estatístico de Transtornos Mentais
Avaliação da Deficiência
Feminino
Seres Humanos
Estudos Longitudinais
Masculino
Prevalência
Prognóstico
Escalas de Graduação Psiquiátrica
Qualidade de Vida
Ferimentos e Lesões/epidemiologia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; MULTICENTER STUDY
[Em] Mês de entrada:1705
[Cu] Atualização por classe:180122
[Lr] Data última revisão:
180122
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:161025
[St] Status:MEDLINE


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[PMID]:28598955
[Au] Autor:Somer E; Soffer-Dudek N; Ross CA
[Ad] Endereço:*School of Social Work, University of Haifa, Haifa; †Department of Psychology, Ben-Gurion University of the Negev, Beer-Sheva, Israel; and ‡The Colin A. Ross Institute, Richardson, Texas.
[Ti] Título:The Comorbidity of Daydreaming Disorder (Maladaptive Daydreaming).
[So] Source:J Nerv Ment Dis;205(7):525-530, 2017 Jul.
[Is] ISSN:1539-736X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:To determine the comorbidity profile of individuals meeting criteria for a proposed new disorder, daydreaming disorder (more commonly known as maladaptive daydreaming [MD]), the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) and the Structured Clinical Interview for DSM-IV Dissociative Disorders were administered to 39 participants who met criteria for MD on a structured interview. We determined high rates of comorbidity: 74.4% met criteria for more than three additional disorders, and 41.1% met criteria for more than four. The most frequent comorbid disorder was attention deficit hyperactivity disorder (76.9%); 71.8% met criteria for an anxiety disorder, 66.7% for a depressive disorder, and 53.9% for an obsessive-compulsive or related disorder. Notably, 28.2% have attempted suicide. Individuals meeting criteria for MD have complex psychiatric problems spanning a range of DSM-5 disorders. This finding provides evidence that MD is different than normal daydreaming and that these individuals experience considerable distress and impairment.
[Mh] Termos MeSH primário: Transtornos de Adaptação
Transtornos Dissociativos
Fantasia
Transtornos Mentais
[Mh] Termos MeSH secundário: Transtornos de Adaptação/classificação
Transtornos de Adaptação/epidemiologia
Transtornos de Adaptação/fisiopatologia
Adolescente
Adulto
Transtornos de Ansiedade/epidemiologia
Transtorno do Deficit de Atenção com Hiperatividade/epidemiologia
Comorbidade
Transtorno Depressivo/epidemiologia
Transtornos Dissociativos/classificação
Transtornos Dissociativos/epidemiologia
Transtornos Dissociativos/fisiopatologia
Feminino
Seres Humanos
Masculino
Transtornos Mentais/epidemiologia
Meia-Idade
Transtorno Obsessivo-Compulsivo/epidemiologia
Tentativa de Suicídio/estatística & dados numéricos
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170719
[Lr] Data última revisão:
170719
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170610
[St] Status:MEDLINE
[do] DOI:10.1097/NMD.0000000000000685


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[PMID]:28154337
[Au] Autor:Nakamura Y; Kanemoto E; Kajizono M; Kitamura Y; Sendo T
[Ad] Endereço:Department of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Okayama University.
[Ti] Título:Investigation of Mental Disorders in Lung Cancer Outpatients: A Retrospective Analysis.
[So] Source:Yakugaku Zasshi;137(2):241-246, 2017.
[Is] ISSN:1347-5231
[Cp] País de publicação:Japan
[La] Idioma:jpn
[Ab] Resumo:Cancer patients often develop mental conditions, including anxiety and depressive disorder. And, patients with chemotherapy often exhibit mental changes including anxiety and depressive disorder. Furthermore, it is well known that the frequency of delirium is increased in cancer patients receiving terminal care. Thus, the psychiatric and cognitive functions of cancer survivors are significantly influenced by their quality of life. In this study, we performed a retrospective analysis to identify the risk factors for psychiatric disorders in lung cancer survivors. Most lung cancer survivors that were diagnosed with psychiatric disorders had stage 4 disease. In addition, it was found that an increase in disease stage and high doses of opioids are associated with an increased risk of psychiatric disorders in lung cancer survivors. These findings suggest that it is necessary to consider the mental changes experienced by lung cancer patients during disease progression.
[Mh] Termos MeSH primário: Transtornos de Ansiedade/etiologia
Delírio/etiologia
Transtorno Depressivo/etiologia
Registros Eletrônicos de Saúde
Neoplasias Pulmonares/complicações
Pacientes Ambulatoriais
[Mh] Termos MeSH secundário: Transtornos de Adaptação/epidemiologia
Transtornos de Adaptação/etiologia
Idoso
Analgésicos Opioides/efeitos adversos
Transtornos de Ansiedade/epidemiologia
Delírio/epidemiologia
Transtorno Depressivo/epidemiologia
Feminino
Seres Humanos
Masculino
Meia-Idade
Estadiamento de Neoplasias
Qualidade de Vida
Estudos Retrospectivos
Índice de Gravidade de Doença
Assistência Terminal
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Analgesics, Opioid)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:171016
[Lr] Data última revisão:
171016
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170204
[St] Status:MEDLINE
[do] DOI:10.1248/yakushi.16-00226


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[PMID]:28144895
[Au] Autor:Li H; Lin Y; Chen J; Wang X; Wu Q; Li Q; Chen Z
[Ad] Endereço:Department of Medical Imaging, Fuzhou General Hospital, Second Military Medical University, No.156, West Erhuan Road, Fuzhou, 350025, Fujian, China.
[Ti] Título:Abnormal regional homogeneity and functional connectivity in adjustment disorder of new recruits: a resting-state fMRI study.
[So] Source:Jpn J Radiol;35(4):151-160, 2017 Apr.
[Is] ISSN:1867-108X
[Cp] País de publicação:Japan
[La] Idioma:eng
[Ab] Resumo:PURPOSE: To explore the regional spontaneous neural activity and functional connectivity alterations of adjustment disorder (AD) in new recruits with in vivo resting-state functional MR (rs-fMRI). MATERIALS AND METHODS: Resting-state fMRI was performed in 31 recruits with AD and in 31 control recruits. Regional homogeneity (ReHo) was used to detect the regional synchronizing features of neuronal activations. Correlative analysis was performed to investigate the relationship between the Symptom Check List-90 (SCL-90) score and ReHo in regions with significant group differences. Regions with significant correlation were then defined as regions of interest (ROIs), and seed-ROI based whole-brain functional connectivity was performed. RESULTS: Compared with the controls, patients with AD had significantly lower ReHo in the left posterior cerebellar lobe, bilateral medial orbitofrontal cortex, bilateral caudate and left middle temporal gyrus, whereas regions with enhanced ReHo were confined to bilateral posterior cingulate gyrus/precuneus. Only the left posterior cerebellar lobe showed significant correlation between ReHo and the SCL-90 score, and was defined as the seed ROI. Decreased functional connectivity was found between the ROI and bilateral supplementary motor area. CONCLUSION: This study reveals abnormalities in recruits with AD in baseline brain function activities, which could further improve our understanding of the neural substrates of cognitive impairment in AD.
[Mh] Termos MeSH primário: Transtornos de Adaptação/diagnóstico por imagem
Transtornos de Adaptação/fisiopatologia
Militares/psicologia
[Mh] Termos MeSH secundário: Transtornos de Adaptação/psicologia
Adolescente
Adulto
Encéfalo/diagnóstico por imagem
Encéfalo/fisiopatologia
Estudos de Casos e Controles
Cerebelo/diagnóstico por imagem
Cerebelo/fisiopatologia
Lateralidade Funcional
Seres Humanos
Imagem por Ressonância Magnética/métodos
Masculino
Vias Neurais/diagnóstico por imagem
Vias Neurais/fisiopatologia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:171104
[Lr] Data última revisão:
171104
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170202
[St] Status:MEDLINE
[do] DOI:10.1007/s11604-017-0614-2


  5 / 3991 MEDLINE  
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[PMID]:27866498
[Au] Autor:Cummings EM; Merrilees C; Taylor LK; Goeke-Morey M; Shirlow P
[Ad] Endereço:University of Notre Dame.
[Ti] Título:Emotional insecurity about the community: A dynamic, within-person mediator of child adjustment in contexts of political violence.
[So] Source:Dev Psychopathol;29(1):27-36, 2017 Feb.
[Is] ISSN:1469-2198
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Over 1 billion children worldwide are exposed to political violence and armed conflict. The current conclusions are qualified by limited longitudinal research testing sophisticated process-oriented explanatory models for child adjustment outcomes. In this study, consistent with a developmental psychopathology perspective emphasizing the value of process-oriented longitudinal study of child adjustment in developmental and social-ecological contexts, we tested emotional insecurity about the community as a dynamic, within-person mediating process for relations between sectarian community violence and child adjustment. Specifically, this study explored children's emotional insecurity at a person-oriented level of analysis assessed over 5 consecutive years, with child gender examined as a moderator of indirect effects between sectarian community violence and child adjustment. In the context of a five-wave longitudinal research design, participants included 928 mother-child dyads in Belfast (453 boys, 475 girls) drawn from socially deprived, ethnically homogenous areas that had experienced political violence. Youth ranged in age from 10 to 20 years and were 13.24 (SD = 1.83) years old on average at the initial time point. Greater insecurity about the community measured over multiple time points mediated relations between sectarian community violence and youth's total adjustment problems. The pathway from sectarian community violence to emotional insecurity about the community was moderated by child gender, with relations to emotional insecurity about the community stronger for girls than for boys. The results suggest that ameliorating children's insecurity about community in contexts of political violence is an important goal toward improving adolescents' well-being and adjustment. These results are discussed in terms of their translational research implications, consistent with a developmental psychopathology model for the interface between basic and intervention research.
[Mh] Termos MeSH primário: Adaptação Psicológica
Transtornos de Adaptação/psicologia
Conflitos Armados/psicologia
Dissidências e Disputas
Ajustamento Emocional
Individualidade
Distribuição Espacial da População
Violência/psicologia
[Mh] Termos MeSH secundário: Transtornos de Adaptação/diagnóstico
Adolescente
Criança
Feminino
Seres Humanos
Estudos Longitudinais
Masculino
Relações Mãe-Filho
Irlanda do Norte
Psicopatologia
Carência Psicossocial
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161122
[St] Status:MEDLINE
[do] DOI:10.1017/S0954579416001097


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[PMID]:27748616
[Au] Autor:Moed A; Dix T; Anderson ER; Greene SM
[Ad] Endereço:Department of Human Development and Family Sciences, University of Texas at Austin.
[Ti] Título:Expressing negative emotions to children: Mothers' aversion sensitivity and children's adjustment.
[So] Source:J Fam Psychol;31(2):224-233, 2017 Mar.
[Is] ISSN:1939-1293
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Research is unclear about when expressing negative emotions to children performs valuable socialization and regulatory functions and when, instead, it undermines children's adjustment. In this study, we isolated 1 kind of negative expression to test the aversion sensitivity hypothesis: that rapid increases in mothers' negativity as a function of increases in the aversiveness of children's behavior are uniquely problematic for children. During multiple assessments of a divorcing sample over 2 years (N = 284), 12-min interactions between mothers and their 4- to 11-year-old children were recorded. Forty-seven observed child behaviors were ranked from low to high aversive. Within-dyad changes demonstrated that mothers' general negativity-their tendency to express negative emotion at high rates-was unrelated to children's adjustment. In contrast, mothers' aversion-focused negativity-their tendency to increase negative emotional expression rapidly as the aversiveness of children's behavior increased-predicted children's poor social competence, poor emotion regulation, and externalizing behavior problems at the next assessment. The findings suggest that negative expression that reflects mothers' affective sensitivity to aversive child behavior may promote interaction patterns and adaptations in children that are particularly likely to place children at risk for adjustment problems. (PsycINFO Database Record
[Mh] Termos MeSH primário: Transtornos de Adaptação/psicologia
Comportamento Infantil/psicologia
Emoções/fisiologia
Mães/psicologia
Estresse Psicológico/psicologia
[Mh] Termos MeSH secundário: Adulto
Criança
Pré-Escolar
Feminino
Seres Humanos
Estudos Longitudinais
Masculino
Meia-Idade
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170524
[Lr] Data última revisão:
170524
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161018
[St] Status:MEDLINE
[do] DOI:10.1037/fam0000239


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[PMID]:27216596
[Au] Autor:Appart A; Lange AK; Sievert I; Bihain F; Tordeurs D
[Ad] Endereço:Service de psychiatrie, clinique Saint-Luc, rue Saint-Luc 8, 5004 Bouge, Belgique.
[Ti] Título:[Adjustment disorder and DSM-5: A review].
[Ti] Título:Le trouble de l'adaptation et le DSM-5 : une revue de la littérature..
[So] Source:Encephale;43(1):41-46, 2017 Feb.
[Is] ISSN:0013-7006
[Cp] País de publicação:France
[La] Idioma:fre
[Ab] Resumo:INTRODUCTION: This paper exposes the complexity and discrete characteristic of the adjustment disorder with reference to its clinical and scientific diagnosis. Even though the disorder occurs in frequent clinical circumstances after important life events, such as mobbing, burn-out, unemployment, divorce or separation, pregnancy denial, surgical operation or cancer, the adjustment disorder is often not considered in the diagnosis since better known disorders with similar symptoms prevail, such as major depression and anxiety disorder. Ten years ago, Bottéro had already noticed that the adjustment disorder diagnosis remained rather uncommon with reference to patients he was working with while Langlois assimilated this disorder with an invisible diagnosis. METHODOLOGY: In order to maximize the data collection, we used the article review below and challenged their surveys and results: National Center for Biotechnology Information (NBCI - Pubmed) for international articles and Cairn.info for French literature. Moreover, we targeted the following keywords on the search engine and used articles, which had been published from 1 February 1975 to 31 January 2015: "adjustment", "adjustment disorder" and the French translation "trouble de l'adaptation". RESULTS: One hundred and ninety-one articles matched our search criteria. However, after a closer analysis, solely 105 articles were selected as being of interest. Many articles were excluded since they were related to non-psychiatric fields induced by the term "adaptation". Indeed, the number of corresponding articles found for the adjustment disorder literally pointed-out the lack of existing literature on that topic in comparison to more known disorders such as anxiety disorder (2661 articles) or major depression (5481 articles). This represents up to 50 times more articles in comparison to the number of articles we found on adjustment disorder and up to 20 times more articles for the eating disorder (1994), although the prevalence is not significantly higher than for the adjustment disorder. According to their relevance and their content, we have split the articles into seven subcategories: 1. General description: most scientific articles generally describe the adjustment disorder as being a transition diagnosis, which is ambiguous, marginal and difficult to detect. The findings claim that only a few studies have been conducted on the adjustment disorder despite a high prevalence in the general population and in the clinical field. 2. CLASSIFICATION: the DSM-5 defined the adjustment disorder as a set of different outcomes and syndromes induced by stress after a difficult life event. While the link to other disorders has not been mentioned, the diagnosis of this disorder is no longer excluded or perceived as a secondary diagnosis. The DSM-5 faced criticism from three points of view: the operationalization of the concept of stress, the differential diagnosis and the description. 3. Prevalence: different samples have shown a significantly high prevalence of the adjustment disorder within the population. In addition to the psychiatric pain induced by difficult life events we need to emphasize the fact that 12.5 to 19.4 percent of the patients faced heavy and severe pathologies and depended on clinical care and treatment. 4. Etiology, comorbidity or associated symptomatology: the literature identified the tendency to commit suicide and stressful life events as being two fundamental characteristics of adjustment disorder. The third one is the personality profile. 5. DIFFERENTIAL DIAGNOSIS: that motivates researchers to focus on the adjustment disorder: the differentiation approach as to the major depression. Indeed, the aetiology, the symptomatology and the treatment differ from the adjustment disorder. 6. ASSESSMENT: very recently, Dutch researchers have developed and validated the Diagnostic Interview Adjustment Disorder (DIAD). 7. TREATMENT: in 2014, no data or meta-analysis recommended drug treatment in addition to therapy. In fact, several authors have demonstrated the ineffectiveness of drug therapy. The literature suggests a psychotherapeutic approach to treat adjustment disorder. CONCLUSION: Emotional reactions triggered by life events are responsible for full therapy agendas and for the rush in emergency rooms and hospitals. The reflex when faced with crying, insomnia or suicidal thoughts to give a diagnostic of major depressive disorder s is generally accepted by everyone. The elevated risk to commit suicide and the approved success of remission or healing through treatment (psychotherapy) are two major reasons why several studies promote the importance and the need to identify the adjustment disorder of our patients.
[Mh] Termos MeSH primário: Transtornos de Adaptação/complicações
Transtorno Depressivo Maior/complicações
[Mh] Termos MeSH secundário: Adaptação Psicológica/fisiologia
Transtornos de Adaptação/epidemiologia
Transtornos de Adaptação/psicologia
Transtornos de Ansiedade/complicações
Transtornos de Ansiedade/psicologia
Comorbidade
Transtorno Depressivo Maior/classificação
Transtorno Depressivo Maior/epidemiologia
Transtorno Depressivo Maior/psicologia
Seres Humanos
Transtornos da Personalidade/complicações
Transtornos da Personalidade/epidemiologia
Transtornos da Personalidade/psicologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170926
[Lr] Data última revisão:
170926
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160525
[St] Status:MEDLINE


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[PMID]:27075681
[Au] Autor:Bouvette-Turcot AA; Bernier A; Leblanc É
[Ad] Endereço:University of Montreal, Montreal, QC, Canada.
[Ti] Título:Maternal Psychosocial Maladjustment and Child Internalizing Symptoms: Investigating the Modulating Role of Maternal Sensitivity.
[So] Source:J Abnorm Child Psychol;45(1):157-170, 2017 Jan.
[Is] ISSN:1573-2835
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:In light of evidence suggesting that maternal adaptation may impact early child emotional development, this study investigated the interactive effects of maternal psychosocial maladjustment and maternal sensitivity on child internalizing symptoms, with the aim of investigating the potentially protective function of maternal sensitivity. Families (N = 71 to 106 across measures, with gender spread almost evenly: number of boys = 31 to 51 across measures) took part in four assessments between child ages 1 and 3 years. Mothers completed measures of parental stress, psychological distress, and marital satisfaction when their children were between 12 and 15 months. A composite score of maternal psychosocial maladjustment was derived from these measures. Maternal sensitivity was rated by trained observers at 12 months following a home visit. Child internalizing symptoms were assessed by both parents when the child was 2 and 3 years old. Hierarchical regressions revealed that increased maternal psychosocial maladjustment was related to more internalizing symptoms in children, however only among children of less sensitive mothers. In contrast, children of more sensitive mothers appeared to be protected. This was observed with maternal reports at 2 years, and both maternal and paternal reports at 3 years. These results suggest that young children may be differentially affected by their parents' emotional adjustment, while highlighting the pivotal protective role of maternal sensitivity in this process.
[Mh] Termos MeSH primário: Transtornos de Adaptação/psicologia
Ansiedade/psicologia
Comportamento Infantil/psicologia
Depressão/psicologia
Comportamento Materno/psicologia
[Mh] Termos MeSH secundário: Adulto
Pré-Escolar
Feminino
Seres Humanos
Lactente
Masculino
Meia-Idade
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:171020
[Lr] Data última revisão:
171020
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160415
[St] Status:MEDLINE
[do] DOI:10.1007/s10802-016-0154-8


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[PMID]:27043067
[Au] Autor:Ozsoy S; Olguner Eker O; Abdulrezzak U; Esel E
[Ad] Endereço:a Department of Psychiatry , Erciyes University School of Medicine , Kayseri , Turkey.
[Ti] Título:Relationship between orexin A and childhood maltreatment in female patients with depression and anxiety.
[So] Source:Soc Neurosci;12(3):330-336, 2017 Jun.
[Is] ISSN:1747-0927
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: Childhood maltreatment leads to neuroendocrine changes, which may be associated with an increased vulnerability for psychopathology, such as depression and anxiety in later life. This study aimed to investigate the relationship between childhood maltreatment and orexin A levels in patients with depression and anxiety. The study consisted of 27 female outpatients who presented with depressive and/or anxiety symptoms, and 27 healthy female controls. Childhood trauma history was assessed using the childhood trauma questionnaire (CTQ-28) in patients and controls. Serum levels of orexin and cortisol were measured in all subjects. There were positive correlations between serum orexin levels and CTQ total score and between orexin levels and some CTQ subscale scores, such as physical and emotional neglect, in patients. Orexin levels in patients with a positive history of physical and emotional neglect were higher than those in patients with a negative history of them. In the controls, there was a positive correlation between emotional neglect score and serum orexin level. There were no differences in serum levels of orexin and cortisol between patients and controls. Orexin levels may be associated with childhood maltreatment per se, rather than psychopathology, such as depression or anxiety.
[Mh] Termos MeSH primário: Transtornos de Adaptação/sangue
Adultos Sobreviventes de Maus-Tratos Infantis
Transtornos de Ansiedade/sangue
Transtorno Depressivo Maior/sangue
Orexinas/sangue
[Mh] Termos MeSH secundário: Adulto
Adultos Sobreviventes de Maus-Tratos Infantis/psicologia
Biomarcadores/sangue
Feminino
Seres Humanos
Hidrocortisona/sangue
Entrevista Psicológica
Meia-Idade
Pacientes Ambulatoriais
Inquéritos e Questionários
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Biomarkers); 0 (Orexins); WI4X0X7BPJ (Hydrocortisone)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170703
[Lr] Data última revisão:
170703
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160405
[St] Status:MEDLINE
[do] DOI:10.1080/17470919.2016.1169216


  10 / 3991 MEDLINE  
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[PMID]:26781759
[Au] Autor:Shimizu K; Kikuchi S; Kobayashi T; Kato S
[Ad] Endereço:Department of Psychiatry, Jichi Medical University, Tochigi, Japan.
[Ti] Título:Persistent complex bereavement disorder: clinical utility and classification of the category proposed for Diagnostic and Statistical Manual of Mental Disorders, 5th edition.
[So] Source:Psychogeriatrics;17(1):17-24, 2017 Jan.
[Is] ISSN:1479-8301
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:AIM: Persistent complex bereavement disorder (PCBD) was proposed as a bereavement-related clinical category in the Diagnostic and Statistical Manual of Mental Disorders, 5th edition, which included the disorder among conditions for further study. This is an independent clinical category in which intense yearning for the deceased continues for at least 12 months. However, the diagnostic features are still inconclusive. We suggest a variation of PCBD for making category from our clinical experiences. METHOD: We presented two representative case studies in which grief caused by bereavement was observed as the root of the pathological condition. We examined the disorder's pathological conditions, diagnoses, and appropriate treatments based on the cases we experienced. RESULTS: Both cases involved elderly women who lost their spouse through illness and experienced prolonged grief for an extended period, resulting in hospital admission. Based on the two cases, we believe that PCBD can also include a psychotic type with hallucinations as a major symptom. While studying PCBD, we took into account specific cultural characteristics of Japanese people and their present day social environment. CONCLUSIONS: Such cases would be suggestive when determining the PCBD clinical category in the future. PCBD is considered to be clinically very useful, especially in an extremely aged society as seen in developed countries, including Japan.
[Mh] Termos MeSH primário: Transtornos de Adaptação
Luto
Manual Diagnóstico e Estatístico de Transtornos Mentais
Pesar
[Mh] Termos MeSH secundário: Idoso
Transtorno Depressivo/diagnóstico
Transtorno Depressivo/psicologia
Feminino
Seres Humanos
Japão
Escalas de Graduação Psiquiátrica
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170404
[Lr] Data última revisão:
170404
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160120
[St] Status:MEDLINE
[do] DOI:10.1111/psyg.12183



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