Base de dados : MEDLINE
Pesquisa : F04.096.208 [Categoria DeCS]
Referências encontradas : 709 [refinar]
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[PMID]:29049280
[Au] Autor:Geissmann Q; Garcia Rodriguez L; Beckwith EJ; French AS; Jamasb AR; Gilestro GF
[Ad] Endereço:Department of Life Sciences, Imperial College London, London, United Kingdom.
[Ti] Título:Ethoscopes: An open platform for high-throughput ethomics.
[So] Source:PLoS Biol;15(10):e2003026, 2017 Oct.
[Is] ISSN:1545-7885
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Here, we present the use of ethoscopes, which are machines for high-throughput analysis of behavior in Drosophila and other animals. Ethoscopes provide a software and hardware solution that is reproducible and easily scalable. They perform, in real-time, tracking and profiling of behavior by using a supervised machine learning algorithm, are able to deliver behaviorally triggered stimuli to flies in a feedback-loop mode, and are highly customizable and open source. Ethoscopes can be built easily by using 3D printing technology and rely on Raspberry Pi microcomputers and Arduino boards to provide affordable and flexible hardware. All software and construction specifications are available at http://lab.gilest.ro/ethoscope.
[Mh] Termos MeSH primário: Comportamento Animal/fisiologia
Drosophila melanogaster/fisiologia
Etologia/instrumentação
[Mh] Termos MeSH secundário: Algoritmos
Animais
Etologia/métodos
Aprendizado de Máquina
Microcomputadores
Impressão Tridimensional
Reprodutibilidade dos Testes
Software
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171105
[Lr] Data última revisão:
171105
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171020
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pbio.2003026


  2 / 709 MEDLINE  
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[PMID]:29020013
[Au] Autor:Laugeray A; Herzine A; Perche O; Richard O; Montecot-Dubourg C; Menuet A; Mazaud-Guittot S; Lesné L; Jegou B; Mortaud S
[Ad] Endereço:Immunologie et Neurogénétique Expérimentales et Moléculaires - UMR7355 CNRS - Orléans, France.
[Ti] Título:In utero and lactational exposure to low-doses of the pyrethroid insecticide cypermethrin leads to neurodevelopmental defects in male mice-An ethological and transcriptomic study.
[So] Source:PLoS One;12(10):e0184475, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Accumulating evidence suggests that developmental exposure to environmental chemicals may modify the course of brain development, ultimately leading to neuropsychiatric / neurodegenerative disorders later in life. In the present study, we assessed the impact of one of the most frequently used pesticides in both residential and agricultural applications - the synthetic pyrethroid cypermethrin (CYP) - on developmental neurotoxicity (DNT). Female mice were perinatally exposed to low doses of CYP (5 and 20 mg/kg body weight) from gestation to postnatal day 15. Behavioral analyses were performed during the offspring's early life and during adulthood. Postnatal analyses revealed that perinatal exposure to CYP disturbed motor development without modifying sensory and communicative skills. We found that later in life, CYP-exposed offspring expressed maladaptive behaviors in response to highly challenging tasks and abnormal sociability. Transcriptomic analyses performed in the offspring's brain at the end of the exposure, highlighted mitochondrial dysfunction as a relevant pathomechanism underlying CYP-induced DNT. Interestingly, several genes involved in proteostasis maintenance were also shown to be dysregulated suggesting that alterations in biogenesis, folding, trafficking and degradation of proteins may significantly contribute to CYP-related DNT. From a regulatory perspective, this study highlights that behavioral and transcriptomic analyses are complementary tools providing useful direction for better DNT characterization, and as such, should be used together more systematically.
[Mh] Termos MeSH primário: Etologia/métodos
Inseticidas/toxicidade
Lactação/efeitos dos fármacos
Transtornos do Neurodesenvolvimento/genética
Efeitos Tardios da Exposição Pré-Natal/genética
Piretrinas/toxicidade
Transcriptoma/genética
[Mh] Termos MeSH secundário: Animais
Animais Recém-Nascidos
Comportamento Animal
Encéfalo/crescimento & desenvolvimento
Cognição/efeitos dos fármacos
Feminino
Regulação da Expressão Gênica no Desenvolvimento/efeitos dos fármacos
Masculino
Camundongos
Camundongos Endogâmicos CBA
Anotação de Sequência Molecular
Transtornos do Neurodesenvolvimento/patologia
Gravidez
RNA Mensageiro/genética
RNA Mensageiro/metabolismo
Comportamento Social
Estresse Fisiológico/efeitos dos fármacos
Transcriptoma/efeitos dos fármacos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Insecticides); 0 (Pyrethrins); 0 (RNA, Messenger); 1TR49121NP (cypermethrin)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171031
[Lr] Data última revisão:
171031
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171012
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0184475


  3 / 709 MEDLINE  
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[PMID]:28419550
[Au] Autor:Klegarth AR; Hollocher H; Jones-Engel L; Shaw E; Lee BPY; Feeney T; Holmes D; Laguea D; Fuentes A
[Ad] Endereço:Department of Biological Sciences, University of Notre Dame, Notre Dame, Indiana.
[Ti] Título:Urban primate ranging patterns: GPS-collar deployments for Macaca fascicularis and M. sylvanus.
[So] Source:Am J Primatol;79(5), 2017 May.
[Is] ISSN:1098-2345
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The global increase in urbanization is leading to heavier interface between humans and wildlife. Within these anthropogenic landscapes, little is known about ranging patterns, particularly with regard to urban primates. Here we present the results of the first long-term deployment of multiple GPS collars on two species of macaques to investigate the impacts of urbanization on urban primate ranging patterns in Singapore and Gibraltar. Collars data acquisition were excellent with respect to the amount, quality, and accuracy of data collected; however, remote connectivity and drop-off functionality was poor across all deployments. Analyses highlighted high variability in ranging patterns between individuals within each species that aligned with access to human food resources and patterns of tourism. Individuals from troops with less access to human food had much larger home, core, and day ranges relative to those with regular provisioning or raiding opportunities. Almost no temporal range overlap was observed between any focal individuals at either site and spatial overlap was low for all but two troops at each site. We found no relationship between anthropogenic schedules and changes in ranging patterns. Significant seasonal variation existed for daily path length and day range size for both the Singapore long-tailed and the Gibraltar Barbary macaques, with long-tailed macaques increasing their range during the equatorial monsoon season and Barbary macaques increasing their range during drier, summer months. This study highlights how the behavioral plasticity found within the genus Macaca is reflected in ranging pattern variability within urban environments.
[Mh] Termos MeSH primário: Distribuição Animal
Etologia
Sistemas de Informação Geográfica
Macaca/fisiologia
[Mh] Termos MeSH secundário: Animais
Cidades
Etologia/instrumentação
Feminino
Gibraltar
Comportamento de Retorno ao Território Vital
Macaca fascicularis/fisiologia
Masculino
Estações do Ano
Singapura
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170524
[Lr] Data última revisão:
170524
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170419
[St] Status:MEDLINE
[do] DOI:10.1002/ajp.22633


  4 / 709 MEDLINE  
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[PMID]:28412938
[Au] Autor:Dammhahn M; Randriamoria TM; Goodman SM
[Ad] Endereço:Animal Ecology, Institute for Biochemistry and Biology, Faculty of Natural Sciences, University of Potsdam, Maulbeerallee 1, 14469, Potsdam, Germany. melanie.dammhahn@uni-potsdam.de.
[Ti] Título:Broad and flexible stable isotope niches in invasive non-native Rattus spp. in anthropogenic and natural habitats of central eastern Madagascar.
[So] Source:BMC Ecol;17(1):16, 2017 Apr 17.
[Is] ISSN:1472-6785
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Rodents of the genus Rattus are among the most pervasive and successful invasive species, causing major vicissitudes in native ecological communities. A broad and flexible generalist diet has been suggested as key to the invasion success of Rattus spp. Here, we use an indirect approach to better understand foraging niche width, plasticity, and overlap within and between introduced Rattus spp. in anthropogenic habitats and natural humid forests of Madagascar. RESULTS: Based on stable carbon and nitrogen isotope values measured in hair samples of 589 individual rodents, we found that Rattus rattus had an extremely wide foraging niche, encompassing the isotopic space covered by a complete endemic forest-dwelling Malagasy small mammal community. Comparisons of Bayesian standard ellipses, as well as (multivariate) mixed-modeling analyses, revealed that the stable isotope niche of R. rattus tended to change seasonally and differed between natural forests and anthropogenic habitats, indicating plasticity in feeding niches. In co-occurrence, R. rattus and Rattus norvegicus partitioned feeding niches. Isotopic mismatch of signatures of individual R. rattus and the habitat in which they were captured, indicate frequent dispersal movements for this species between natural forest and anthropogenic habitats. CONCLUSIONS: Since R. rattus are known to transmit a number of zoonoses, potentially affecting communities of endemic small mammals, as well as humans, these movements presumably increase transmission potential. Our results suggest that due to their generalist diet and potential movement between natural forest and anthropogenic habitats, Rattus spp. might affect native forest-dependent Malagasy rodents as competitors, predators, and disease vectors. The combination of these effects helps explain the invasion success of Rattus spp. and the detrimental effects of this genus on the endemic Malagasy rodent fauna.
[Mh] Termos MeSH primário: Dieta
Ecologia/métodos
Etologia/métodos
Comportamento Alimentar
Espécies Introduzidas
Ratos/fisiologia
[Mh] Termos MeSH secundário: Animais
Isótopos de Carbono/análise
Madagáscar
Isótopos de Nitrogênio/análise
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Carbon Isotopes); 0 (Nitrogen Isotopes)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170424
[Lr] Data última revisão:
170424
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170418
[St] Status:MEDLINE
[do] DOI:10.1186/s12898-017-0125-0


  5 / 709 MEDLINE  
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[PMID]:28385158
[Au] Autor:Itskovits E; Levine A; Cohen E; Zaslaver A
[Ad] Endereço:Department of Genetics, The Silberman Institute of Life Science, Edmond J. Safra Campus, The Hebrew University of Jerusalem, Jerusalem, 91904, Israel.
[Ti] Título:A multi-animal tracker for studying complex behaviors.
[So] Source:BMC Biol;15(1):29, 2017 Apr 06.
[Is] ISSN:1741-7007
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Animals exhibit astonishingly complex behaviors. Studying the subtle features of these behaviors requires quantitative, high-throughput, and accurate systems that can cope with the often rich perplexing data. RESULTS: Here, we present a Multi-Animal Tracker (MAT) that provides a user-friendly, end-to-end solution for imaging, tracking, and analyzing complex behaviors of multiple animals simultaneously. At the core of the tracker is a machine learning algorithm that provides immense flexibility to image various animals (e.g., worms, flies, zebrafish, etc.) under different experimental setups and conditions. Focusing on C. elegans worms, we demonstrate the vast advantages of using this MAT in studying complex behaviors. Beginning with chemotaxis, we show that approximately 100 animals can be tracked simultaneously, providing rich behavioral data. Interestingly, we reveal that worms' directional changes are biased, rather than random - a strategy that significantly enhances chemotaxis performance. Next, we show that worms can integrate environmental information and that directional changes mediate the enhanced chemotaxis towards richer environments. Finally, offering high-throughput and accurate tracking, we show that the system is highly suitable for longitudinal studies of aging- and proteotoxicity-associated locomotion deficits, enabling large-scale drug and genetic screens. CONCLUSIONS: Together, our tracker provides a powerful and simple system to study complex behaviors in a quantitative, high-throughput, and accurate manner.
[Mh] Termos MeSH primário: Comportamento Animal
Caenorhabditis elegans/fisiologia
Etologia/métodos
[Mh] Termos MeSH secundário: Envelhecimento/fisiologia
Algoritmos
Animais
Quimiotaxia
Aprendizado de Máquina
Degeneração Neural/patologia
Proteínas/toxicidade
Software
Fatores de Tempo
Gravação em Vídeo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Proteins)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171016
[Lr] Data última revisão:
171016
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170408
[St] Status:MEDLINE
[do] DOI:10.1186/s12915-017-0363-9


  6 / 709 MEDLINE  
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[PMID]:28353227
[Au] Autor:Sarnyai Z; Guest PC
[Ad] Endereço:Laboratory of Psychiatric Neuroscience, Australian Institute of Tropical Health and Medicine, Townsville, QLD, Australia. zoltan.sarnyai@jcu.edu.au.
[Ti] Título:Connecting Brain Proteomics with Behavioural Neuroscience in Translational Animal Models of Neuropsychiatric Disorders.
[So] Source:Adv Exp Med Biol;974:97-114, 2017.
[Is] ISSN:0065-2598
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Modelling psychiatric disorders in animals has been hindered by several challenges related to our poor understanding of the disease causes. This chapter describes recent advances in translational research which may lead to animal models and relevant proteomic biomarkers that can be informative about disease mechanisms and potential new therapeutic targets. The review focuses on the behavioural and molecular correlates in models of schizophrenia and major depressive disorder, as guided by recently established Research Domain Criteria (RDoC). This approach is based on providing proteomic data for aetiologically driven, behaviourally well-characterised animal models to link discovered biomarker candidates with the human disease.
[Mh] Termos MeSH primário: Biomarcadores/análise
Química Encefálica
Modelos Animais de Doenças
Etologia/métodos
Transtornos Mentais/metabolismo
Proteínas do Tecido Nervoso/análise
Neurociências/métodos
Proteômica/métodos
Pesquisa Médica Translacional/métodos
[Mh] Termos MeSH secundário: Animais
Comportamento Animal/fisiologia
Descoberta de Drogas
Seres Humanos
Transtornos Mentais/induzido quimicamente
Transtornos Mentais/tratamento farmacológico
Transtornos Mentais/etiologia
Camundongos
Camundongos Mutantes Neurológicos
Proteínas do Tecido Nervoso/genética
Doenças do Sistema Nervoso/induzido quimicamente
Doenças do Sistema Nervoso/genética
Doenças do Sistema Nervoso/psicologia
Primatas
Psicotrópicos/farmacologia
Ratos
Especificidade da Espécie
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Biomarkers); 0 (Nerve Tissue Proteins); 0 (Psychotropic Drugs)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170928
[Lr] Data última revisão:
170928
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170330
[St] Status:MEDLINE
[do] DOI:10.1007/978-3-319-52479-5_6


  7 / 709 MEDLINE  
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[PMID]:27942982
[Au] Autor:Matsuzawa T
[Ad] Endereço:Institute of Advanced Study, Kyoto University, Kyoto, Japan. matsuzawa.tetsuro.8w@kyoto-u.ac.jp.
[Ti] Título:Primates Social Impact Award 2016.
[So] Source:Primates;58(1):5, 2017 Jan.
[Is] ISSN:1610-7365
[Cp] País de publicação:Japan
[La] Idioma:eng
[Mh] Termos MeSH primário: Distinções e Prêmios
Etologia/história
Primatas/fisiologia
[Mh] Termos MeSH secundário: Animais
História do Século XXI
[Pt] Tipo de publicação:BIOGRAPHY; EDITORIAL; HISTORICAL ARTICLE
[Ps] Nome de pessoa como assunto:van Hooff JA; Lukkenaar B
[Em] Mês de entrada:1705
[Cu] Atualização por classe:171014
[Lr] Data última revisão:
171014
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161213
[St] Status:MEDLINE
[do] DOI:10.1007/s10329-016-0592-5


  8 / 709 MEDLINE  
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[PMID]:27906515
[Au] Autor:Blumberg MS
[Ad] Endereço:Department of Psychological & Brain Sciences, The University of Iowa, Iowa City, IA, USA.
[Ti] Título:Development evolving: the origins and meanings of instinct.
[So] Source:Wiley Interdiscip Rev Cogn Sci;8(1-2), 2017 Jan.
[Is] ISSN:1939-5086
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:How do migratory birds, herding dogs, and navigating sea turtles do the amazing things that they do? For hundreds of years, scientists and philosophers have struggled over possible explanations. In time, one word came to dominate the discussion: instinct. It became the catch-all explanation for those adaptive and complex abilities that do not obviously result from learning or experience. Today, various animals are said to possess a survival instinct, migratory instinct, herding instinct, maternal instinct, or language instinct. But a closer look reveals that these and other 'instincts' are not satisfactorily described as inborn, pre-programmed, hardwired, or genetically determined. Rather, research in this area teaches us that species-typical behaviors develop-and they do so in every individual under the guidance of species-typical experiences occurring within reliable ecological contexts. WIREs Cogn Sci 2017, 8:e1371. doi: 10.1002/wcs.1371 For further resources related to this article, please visit the WIREs website.
[Mh] Termos MeSH primário: Comportamento Animal
Evolução Biológica
Instinto
[Mh] Termos MeSH secundário: Animais
Etologia
Seres Humanos
Aprendizagem
Especificidade da Espécie
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170324
[Lr] Data última revisão:
170324
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161202
[St] Status:MEDLINE
[do] DOI:10.1002/wcs.1371


  9 / 709 MEDLINE  
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[PMID]:27461577
[Au] Autor:McGrew WC
[Ad] Endereço:Division of Biological Anthropology, Department of Archaeology and Anthropology, University of Cambridge, Fitzwilliam Street, Cambridge, CB2 1QH, UK. wcm21@cam.ac.uk.
[Ti] Título:Field studies of Pan troglodytes reviewed and comprehensively mapped, focussing on Japan's contribution to cultural primatology.
[So] Source:Primates;58(1):237-258, 2017 Jan.
[Is] ISSN:1610-7365
[Cp] País de publicação:Japan
[La] Idioma:eng
[Ab] Resumo:Field studies done over decades of wild chimpanzees in East, Central and West Africa have yielded impressive, cumulative findings in cultural primatology. Japanese primatologists have been involved in this advance from the outset, over a wide variety of topics. Here I review the origins and development of field studies of Pan troglodytes, then assess their progress based on analogy between cultural primatology and cultural anthropology, through four stages: natural history, ethnography, ethnology, and intuition. Then, I focus on six topics that continue to yield informative debate: technology, universals, nuanced variation, archaeology, applied primatology, and ecology. Finally, I offer a map of sites of field study of wild chimpanzees. It is clear that Japanese primatologists have made a significant contribution to East-West scientific exchange, especially at the field sites of Bossou and Mahale.
[Mh] Termos MeSH primário: Comportamento Animal
Etologia
Pan troglodytes/fisiologia
Pan troglodytes/psicologia
[Mh] Termos MeSH secundário: Animais
Japão
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1705
[Cu] Atualização por classe:171014
[Lr] Data última revisão:
171014
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160728
[St] Status:MEDLINE
[do] DOI:10.1007/s10329-016-0554-y


  10 / 709 MEDLINE  
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[PMID]:27687926
[Au] Autor:Savolainen S; Telkänranta H; Junnila J; Hautala J; Airaksinen S; Juppo A; Raekallio M; Vainio O
[Ad] Endereço:Department of Equine and Small Animal Medicine, University of Helsinki, P.O. Box 57, 00014 Helsinki, Finland. Electronic address: saila.savolainen@helsinki.fi.
[Ti] Título:A novel set of behavioural indicators for measuring perception of food by cats.
[So] Source:Vet J;216:53-8, 2016 Oct.
[Is] ISSN:1532-2971
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Behavioural indicators provide a promising approach for objective assessment of the perceptions of animals. In cats, the frequency of specific behaviours as indicators of perception has been studied in connection with food palatability. The aim of this study was to expand that knowledge by identifying behavioural indicators correlating with three degrees of palatability. Thirty-four pet cats were presented with three types of items: favoured food (FF), favoured food with a placebo mini-tablet hidden inside (TFF) and non-favoured food (NFF). The items were presented in a pseudo-randomised sequence, with six trials per item and 18 trials per cat. The behaviour of cats before, during and after eating, or refusing to eat, was video-recorded. Two trained observers, blinded to the types of food items, independently determined the frequency of 16 behavioural patterns on the video recordings. The data were analysed using a mixed logistic regression model. Five behavioural patterns differentiated FF from NFF; 'flick ears backwards', 'lick nose, not eaten', 'flick tail' and 'groom body' were more frequent with NFF, whereas 'lick lips' was more frequent with FF. One indicator, 'drop item', was more frequent with TFF than FF. These findings provide evidence of new behavioural indicators for objective assessment of food perception in cats. The findings also have practical applicability in designing a novel palatability test to be utilised in developing veterinary pharmaceuticals with improved palatability for cats.
[Mh] Termos MeSH primário: Criação de Animais Domésticos/métodos
Gatos/fisiologia
Etologia/métodos
Preferências Alimentares
Percepção
[Mh] Termos MeSH secundário: Animais
Comportamento Animal
Ingestão de Alimentos
Placebos/administração & dosagem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Placebos)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161001
[St] Status:MEDLINE



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