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[PMID]:28797949
[Au] Autor:van Praag VM; Rueten-Budde AJ; Jeys LM; Laitinen MK; Pollock R; Aston W; van der Hage JA; Dijkstra PDS; Ferguson PC; Griffin AM; Willeumier JJ; Wunder JS; van de Sande MAJ; Fiocco M
[Ad] Endereço:Department of Orthopaedic Surgery, Leiden University Medical Centre, Albinusdreef 2, 2333 ZA Leiden, The Netherlands.
[Ti] Título:A prediction model for treatment decisions in high-grade extremity soft-tissue sarcomas: Personalised sarcoma care (PERSARC).
[So] Source:Eur J Cancer;83:313-323, 2017 Sep.
[Is] ISSN:1879-0852
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: To support shared decision-making, we developed the first prediction model for patients with primary soft-tissue sarcomas of the extremities (ESTS) which takes into account treatment modalities, including applied radiotherapy (RT) and achieved surgical margins. The PERsonalised SARcoma Care (PERSARC) model, predicts overall survival (OS) and the probability of local recurrence (LR) at 3, 5 and 10 years. AIM: Development and validation, by internal validation, of the PERSARC prediction model. METHODS: The cohort used to develop the model consists of 766 ESTS patients who underwent surgery, between 2000 and 2014, at five specialised international sarcoma centres. To assess the effect of prognostic factors on OS and on the cumulative incidence of LR (CILR), a multivariate Cox proportional hazard regression and the Fine and Gray model were estimated. Predictive performance was investigated by using internal cross validation (CV) and calibration. The discriminative ability of the model was determined with the C-index. RESULTS: Multivariate Cox regression revealed that age and tumour size had a significant effect on OS. More importantly, patients who received RT showed better outcomes, in terms of OS and CILR, than those treated with surgery alone. Internal validation of the model showed good calibration and discrimination, with a C-index of 0.677 and 0.696 for OS and CILR, respectively. CONCLUSIONS: The PERSARC model is the first to incorporate known clinical risk factors with the use of different treatments and surgical outcome measures. The developed model is internally validated to provide a reliable prediction of post-operative OS and CILR for patients with primary high-grade ESTS. LEVEL OF SIGNIFICANCE: level III.
[Mh] Termos MeSH primário: Técnicas de Apoio para a Decisão
Terapia Centrada na Pessoa/métodos
Sarcoma
Neoplasias de Tecidos Moles
[Mh] Termos MeSH secundário: Adulto
Fatores Etários
Feminino
Seres Humanos
Incidência
Masculino
Meia-Idade
Modelos Biológicos
Recidiva Local de Neoplasia/epidemiologia
Recidiva Local de Neoplasia/etiologia
Análise de Regressão
Estudos Retrospectivos
Fatores de Risco
Sarcoma/epidemiologia
Sarcoma/patologia
Sarcoma/cirurgia
Neoplasias de Tecidos Moles/epidemiologia
Neoplasias de Tecidos Moles/patologia
Neoplasias de Tecidos Moles/cirurgia
Análise de Sobrevida
[Pt] Tipo de publicação:JOURNAL ARTICLE; MULTICENTER STUDY; OBSERVATIONAL STUDY
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170911
[Lr] Data última revisão:
170911
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170812
[St] Status:MEDLINE


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[PMID]:28157725
[Au] Autor:Ghafoori B; Hansen MC; Garibay E; Korosteleva O
[Ad] Endereço:California State University, Long Beach, CA.
[Ti] Título:Feasibility of Training Frontline Therapists in Prolonged Exposure: A Randomized Controlled Pilot Study of Treatment of Complex Trauma in Diverse Victims of Crime and Violence.
[So] Source:J Nerv Ment Dis;205(4):283-293, 2017 Apr.
[Is] ISSN:1539-736X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The study aims were to determine whether prolonged exposure (PE) improved mental health and was feasible to implement by frontline clinicians in a culturally diverse sample with complex trauma. Seventy-one individuals were randomly assigned to PE or person-centered therapy (PCT). Outcome measures were administered at baseline and sessions 3, 6, 9, and 12. Mixed modeling was used to regress outcome measures on time, treatment group, and number of visits. Individuals who received PE showed significant moderate association with decline in reported posttraumatic stress disorder (PTSD) symptoms as noted by the PTSD Checklist for DSM-5 (p = 0.05) compared with PCT. Results indicated improved scores on all measures at each follow-up time point compared with baseline (p ≤ 0.01). PE was feasible, shown by positive recruitment and ability of clinicians to effectively implement and maintain treatment fidelity. Findings suggest that PE can be effective for treating complex trauma when used by clinicians in community settings.
[Mh] Termos MeSH primário: Vítimas de Crime/reabilitação
Terapia Implosiva/métodos
Avaliação de Resultados (Cuidados de Saúde)/métodos
Terapia Centrada na Pessoa/métodos
Transtornos de Estresse Pós-Traumáticos/terapia
Violência/psicologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Estudos de Viabilidade
Feminino
Seres Humanos
Terapia Implosiva/educação
Masculino
Meia-Idade
Projetos Piloto
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170529
[Lr] Data última revisão:
170529
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170204
[St] Status:MEDLINE
[do] DOI:10.1097/NMD.0000000000000659


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[PMID]:27993344
[Au] Autor:Cuijpers P; Ebert DD; Acarturk C; Andersson G; Cristea IA
[Ad] Endereço:VU University Amsterdam, EMGO Institute for Health and Care Research, and Innovation Incubator. Electronic address: p.cuijpers@vu.nl.
[Ti] Título:Personalized Psychotherapy for Adult Depression: A Meta-Analytic Review.
[So] Source:Behav Ther;47(6):966-980, 2016 Nov.
[Is] ISSN:1878-1888
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Personalized medicine is aimed at identifying which characteristics of an individual predict the outcome of a specific treatment, in order to get a better match between the individual and the treatment received. We conducted a systematic review and meta-analysis of randomized trials comparing two psychotherapies directly in a group of depressed patients with a specific characteristic. We focused on the six most examined types of psychotherapy for adult depression. Our searches resulted in 41 studies with 2,741 patients who met inclusion criteria. These 41 studies examined 27 specific characteristics of patients. Power calculations indicated that we would need 4 studies for each characteristic to find a clinically relevant effect size set at g = 0.50 and 16 studies for an effect size of 0.24. Only 3 patient characteristics were found to have sufficient power and to significantly moderate treatment outcomes. Cognitive-behavioral therapy was found to be more effective than other therapies in older adults (g = 0.29), in patients with comorbid addictive disorders (g = 0.31), and in university students (g = 0.46). Risk of bias was considerable in most of the included studies. It was estimated that it will take another 326 years to have sufficient statistical power for showing an effect size of g = 0.50 of the 27 characteristics, and 1,372 years to show an effect size of 0.24. Although several dozens of studies have compared the effects of psychotherapies in specific target groups, we will need to develop more powerful alternatives to comparative outcome studies in order to identify personalized treatments for depression.
[Mh] Termos MeSH primário: Transtorno Depressivo/terapia
Terapia Centrada na Pessoa/métodos
Medicina de Precisão/métodos
Psicoterapia/métodos
[Mh] Termos MeSH secundário: Terapia Cognitiva/métodos
Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE; META-ANALYSIS; REVIEW
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171101
[Lr] Data última revisão:
171101
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161221
[St] Status:MEDLINE


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[PMID]:27727282
[Au] Autor:Mukwege D; Berg M
[Ad] Endereço:Panzi General Referral Hospital, Bukavu, Democratic Republic of Congo.
[Ti] Título:A Holistic, Person-Centred Care Model for Victims of Sexual Violence in Democratic Republic of Congo: The Panzi Hospital One-Stop Centre Model of Care.
[So] Source:PLoS Med;13(10):e1002156, 2016 Oct.
[Is] ISSN:1549-1676
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Denis Mukwege and Marie Berg describe the One Stop Centre at Panzi Hospital in Eastern Democratic Republic of Congo that provides care for girls and women who have been raped in combination with extreme bodily harm.
[Mh] Termos MeSH primário: Terapia Centrada na Pessoa
Delitos Sexuais
[Mh] Termos MeSH secundário: Adolescente
Adulto
Criança
República Democrática do Congo
Feminino
Seres Humanos
Masculino
Modelos Psicológicos
Delitos Sexuais/psicologia
Fatores Socioeconômicos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170529
[Lr] Data última revisão:
170529
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161012
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pmed.1002156


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[PMID]:27697980
[Au] Autor:Tamagawa R; Groff S; Anderson J; Champ S; Deiure A; Looyis J; Faris P; Watson L
[Ad] Endereço:From CancerControl Alberta, Alberta Health Services, Calgary, Alberta, Canada.
[Ti] Título:Effects of a Provincial-Wide Implementation of Screening for Distress on Healthcare Professionals' Confidence and Understanding of Person-Centered Care in Oncology.
[So] Source:J Natl Compr Canc Netw;14(10):1259-1266, 2016 Oct.
[Is] ISSN:1540-1413
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Although published studies report that screening for distress (SFD) improves the quality of care for patients with cancer, little is known about how SFD impacts healthcare professionals (HCPs). OBJECTIVES: This quality improvement project examined the impact of implementing the SFD intervention on HCPs' confidence in addressing patient distress and awareness of person-centered care. PATIENTS AND METHODS: This project involved pre-evaluation and post-evaluation of the impact of implementing SFD. A total of 254 HCPs (cohort 1) were recruited from 17 facilities across the province to complete questionnaires. SFD was then implemented at all cancer care facilities over a 10-month implementation period, after which 157 HCPs (cohort 2) completed post-implementation questionnaires. At regional and community care centers, navigators supported the integration of SFD into routine practice; therefore, the impact of navigators was examined. RESULTS: HCPs in cohort 2 reported significantly greater confidence in managing patients' distress and greater awareness about person-centered care relative to HCPs in cohort 1. HCPs at regional and community sites reported greater awareness in person-centeredness before and after the intervention, and reported fewer negative impacts of SFD relative to HCPs at tertiary sites. Caring for single or multiple tumor types was an effect modifier, with effects observed only in the HCPs treating multiple tumors. CONCLUSIONS: Implementation of SFD was beneficial for HCPs' confidence and awareness of person-centeredness. Factors comprising different models of care, such as having site-based navigators and caring for single or multiple tumors, influenced outcomes.
[Mh] Termos MeSH primário: Atitude do Pessoal de Saúde
Programas de Rastreamento/métodos
Oncologia/normas
Terapia Centrada na Pessoa/métodos
[Mh] Termos MeSH secundário: Estudos de Coortes
Feminino
Pessoal de Saúde
Seres Humanos
Masculino
Inquéritos e Questionários
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170929
[Lr] Data última revisão:
170929
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161005
[St] Status:MEDLINE


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[PMID]:27659392
[Au] Autor:Schindel Martin L; Gillies L; Coker E; Pizzacalla A; Montemuro M; Suva G; McLelland V
[Ad] Endereço:Daphne Cockwell School of Nursing, Ryerson University, Toronto, Ontario, Canada lori.schindelmartin@ryerson.ca.
[Ti] Título:An Education Intervention to Enhance Staff Self-Efficacy to Provide Dementia Care in an Acute Care Hospital in Canada: A Nonrandomized Controlled Study.
[So] Source:Am J Alzheimers Dis Other Demen;31(8):664-677, 2016 Dec.
[Is] ISSN:1938-2731
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Education is needed for enhanced capacity of acute hospitals to provide dementia care. A nonrandomized controlled, repeated-measures design was used to evaluate a dementia education program delivered to an intervention group (IG, n = 468), compared to a wait-listed group (n = 277), representing separate sites of a multisite hospital. Participants completed self-efficacy for dementia and satisfaction measures and provided written descriptions of dementia care collected at baseline, postintervention (IG only), and at 8-week follow-up. Oral narratives were gathered from IG participants 8 weeks postintervention. The IG demonstrated significant improvement in self-efficacy scores from baseline to immediately postintervention (P < .001), sustained at 8 weeks. There were no changes from baseline to 8 weeks postintervention evident in the wait-listed group (P = .21). Intervention group participants described positive impacts including implementation of person-centered care approaches. Implementation of dementia care education programs throughout hospital settings is promising for the enhancement of dementia care.
[Mh] Termos MeSH primário: Demência/enfermagem
Recursos Humanos em Hospital/educação
Autoeficácia
[Mh] Termos MeSH secundário: Canadá
Seguimentos
Seres Humanos
Terapia Centrada na Pessoa
[Pt] Tipo de publicação:CONTROLLED CLINICAL TRIAL; JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171004
[Lr] Data última revisão:
171004
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160924
[St] Status:MEDLINE


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[PMID]:27322874
[Au] Autor:Kolho KL; Ainamo A
[Ad] Endereço:a Children´s Hospital , Helsinki University Central Hospital, University of Helsinki , Helsinki , Finland.
[Ti] Título:Progress in the treatment and outcome of pediatric inflammatory bowel disease patients.
[So] Source:Expert Rev Clin Immunol;12(12):1337-1345, 2016 Dec.
[Is] ISSN:1744-8409
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: The number of pediatric patients with inflammatory bowel disease (IBD), namely Crohn´s disease, ulcerative colitis and unclassified colitis, has rapidly increased in Western countries. Areas covered: This review discusses how the treatment of pediatric IBD patients has improved,with attention given to therapeutic quality and cost. The literature search covers Medline-PubMed and the Cochrane Library, with February 2016 as the last search dates. Similarly to what has been the trend in the management of adult IBD, pediatric IBD therapy has become more active than before. High use of immunosuppressants and the availability of biological therapeutic agents has helped to control the extensive and aggressive course of pediatric IBD. Full disease control at an early phase has advantages such as preserving normal child growth and development, maintaining overall good health and quality of life, as well as decreasing the psychosocial burden of the disease. Expert commentary: A key research direction is to tailor treatment modalities according to anticipated individual phenotype and disease course. Another is to reduce healthcare costs by decreasing the so-far high rate of surgery of pediatric IBD patients, and, instead, to develop a more active approach to treatment than before.
[Mh] Termos MeSH primário: Imunossupressores/uso terapêutico
Doenças Inflamatórias Intestinais/tratamento farmacológico
Complexo Antígeno L1 Leucocitário/uso terapêutico
[Mh] Termos MeSH secundário: Adulto
Criança
Custos de Cuidados de Saúde
Seres Humanos
Doenças Inflamatórias Intestinais/economia
Terapia Centrada na Pessoa
Qualidade de Vida
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Immunosuppressive Agents); 0 (Leukocyte L1 Antigen Complex)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170505
[Lr] Data última revisão:
170505
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160621
[St] Status:MEDLINE


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[PMID]:27229286
[Au] Autor:John RL; Antai-Otong D
[Ad] Endereço:Department of Veterans Affairs-Greater Los Angeles, 11301 Wilshire Boulevard, Los Angeles, CA 90073, USA. Electronic address: Richard.JohnJr@va.gov.
[Ti] Título:Contemporary Treatment Approaches to Major Depression and Bipolar Disorders.
[So] Source:Nurs Clin North Am;51(2):335-51, 2016 Jun.
[Is] ISSN:1558-1357
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Mood disorders have a high incidence of coexisting psychiatric, substance use, and physical disorders. When these disorders are unrecognized and left untreated, patients are likely to have a reduced life expectancy and experience impaired functional and psychosocial deficits and poor quality of life. Psychiatric nurses are poised to address the needs of these patients through various approaches. Although the ideal approach for mood disorders continues to be researched, there is a compilation of data showing that integrated models of treatment that reflect person-centered, strength, and recovery-based principles produce positive clinical outcomes.
[Mh] Termos MeSH primário: Transtorno Bipolar/enfermagem
Transtorno Depressivo Maior/enfermagem
Terapia Centrada na Pessoa/organização & administração
Enfermagem Psiquiátrica/organização & administração
Qualidade de Vida/psicologia
[Mh] Termos MeSH secundário: Transtorno Bipolar/psicologia
Transtorno Depressivo Maior/psicologia
Seres Humanos
Índice de Gravidade de Doença
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170510
[Lr] Data última revisão:
170510
[Sb] Subgrupo de revista:AIM; IM; N
[Da] Data de entrada para processamento:160528
[St] Status:MEDLINE


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Registro de Ensaios Clínicos
PubMed Central Texto completo
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[PMID]:27209068
[Au] Autor:Palstam A; Larsson A; Löfgren M; Ernberg M; Bjersing J; Bileviciute-Ljungar I; Gerdle B; Kosek E; Mannerkorpi K
[Ad] Endereço:Institute of neuroscience and physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. annie.palstam@gu.se.
[Ti] Título:Decrease of fear avoidance beliefs following person-centered progressive resistance exercise contributes to reduced pain disability in women with fibromyalgia: secondary exploratory analyses from a randomized controlled trial.
[So] Source:Arthritis Res Ther;18(1):116, 2016 May 21.
[Is] ISSN:1478-6362
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Fibromyalgia (FM) is characterized by persistent widespread pain, increased pain sensitivity and tenderness. Women with FM also report disability, in terms of negative consequences on activities of daily living. Our recent randomized controlled trial (RCT) is the first study of resistance exercise to show positive effects on pain disability. The resistance exercise program of our RCT emphasized active involvement of participants in planning and progression of the exercise, using the principles of person-centeredness, to support each participant's ability to manage the exercise and the progress of it. The aim of this sub-study was to investigate explanatory factors for reduced pain disability in women with FM participating in a 15-week person-centered progressive resistance exercise program. METHODS: A total of 67 women with FM were included in this sub-study of an RCT examining the effects of person-centered progressive resistance exercise performed twice a week for 15 weeks. Tests of physical capacity and health-related questionnaires were assessed at baseline and after the intervention period. Multivariable stepwise regression was used to analyze explanatory factors for improvements in pain disability. RESULTS: Reduced pain disability was explained by higher pain disability at baseline together with decreased fear avoidance beliefs about physical activity (R (2) = 28, p = 0.005). The improvements in the disability domains of recreation and social activity were explained by decreased fear avoidance beliefs about physical activity together with higher baseline values of each disability domain respectively (R (2) = 32, p = 0.025 and R (2) = 30, p = 0.017). The improvement in occupational disability was explained by higher baseline values of occupational disability (R (2) = 19, p = 0.001). CONCLUSION: The person-centered resistance exercise intervention, based on principles of self-efficacy, had a positive effect on recreational, social and occupational disability. The reduced pain disability seemed to be mediated by decreased fear avoidance beliefs. Age, symptom duration, pain intensity, and muscle strength at baseline had no explanatory value for reduced pain disability, indicating that the person-centered resistance exercise program has the potential to work for anyone with FM who has interest in physical exercise. The trial was registered on October 21, 2010 with ClinicalTrials.gov identification number: NCT01226784 .
[Mh] Termos MeSH primário: Medo/psicologia
Fibromialgia/reabilitação
Dor/psicologia
Terapia Centrada na Pessoa
Treinamento de Resistência/métodos
[Mh] Termos MeSH secundário: Adulto
Idoso
Aprendizagem da Esquiva
Feminino
Fibromialgia/psicologia
Seres Humanos
Meia-Idade
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; MULTICENTER STUDY; RANDOMIZED CONTROLLED TRIAL
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171108
[Lr] Data última revisão:
171108
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160523
[Cl] Clinical Trial:ClinicalTrial
[St] Status:MEDLINE
[do] DOI:10.1186/s13075-016-1007-0


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[PMID]:27112806
[Au] Autor:Martínez T; Suárez-Álvarez J; Yanguas J
[Ad] Endereço:Consejería de Servicios y Derechos Sociales del Principado de Asturias.
[Ti] Título:Instruments for assessing Person Centered Care in Gerontology.
[So] Source:Psicothema;28(2):114-21, 2016 May.
[Is] ISSN:1886-144X
[Cp] País de publicação:Spain
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The assessment of Person Centered Care (PCC) is internationally recognised as an approach of great interest for improving the quality of care of the elderly. The aim of this research is to review the procedures and instruments used in the assessment of services using this approach. METHOD: The measurement instruments designed to assess elderly care services from PCC were reviewed, particularly residential services, day centers and home help. The main databases, research articles, and specialized websites were consulted. RESULTS: Four observational instruments for the assessment of Person Centered Care are described; five for the assessment of physical space; six aimed at discovering users’ opinions; one which records family opinions, and five aimed at professionals, as well as several qualitative tools for self-assessment of centers. CONCLUSIONS: Due to the diversity of instruments available for assessing PCC, and in order to avoid partial evaluations of attention, a combined strategy of assessment is recommended as well as integrating these measures into a broader service evaluation which includes the different strands related to care quality.
[Mh] Termos MeSH primário: Serviços de Saúde para Idosos/normas
Terapia Centrada na Pessoa
Garantia da Qualidade dos Cuidados de Saúde
[Mh] Termos MeSH secundário: Idoso
Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171031
[Lr] Data última revisão:
171031
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160427
[St] Status:MEDLINE
[do] DOI:10.7334/psicothema2015.263



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