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Pesquisa : G01.015 [Categoria DeCS]
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  1 / 29082 MEDLINE  
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[PMID]:27019955
[Au] Autor:García-Arieta A; Gordon J; Potthast H
[Ad] Endereço:Division of Pharmacology and Clinical Evaluation, Department of Human Use Medicines, Spanish Agency for Medicines and Health Care Products, Madrid, Spain. Electronic address: agarciaa@aemps.es.
[Ti] Título:On the Effect of Common Excipients on the Oral Absorption of Class 3 Drugs.
[So] Source:J Pharm Sci;105(4):1353-4, 2016 Apr.
[Is] ISSN:1520-6017
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Excipientes/farmacologia
Absorção Intestinal/efeitos dos fármacos
[Mh] Termos MeSH secundário: Absorção
Administração Oral
Seres Humanos
Solubilidade
[Pt] Tipo de publicação:COMMENT; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Excipients)
[Em] Mês de entrada:1608
[Cu] Atualização por classe:160329
[Lr] Data última revisão:
160329
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160330
[St] Status:MEDLINE


  2 / 29082 MEDLINE  
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[PMID]:25345281
[Au] Autor:Sierant K; Rebizak E; Labuzek K; Okopien B
[Ti] Título:[Drugs malabsorption after bariatric surgery].
[Ti] Título:Zaburzenia wchlaniania leków u chorych po operacjach bariatrycznych..
[So] Source:Pol Merkur Lekarski;37(219):181-5, 2014 Sep.
[Is] ISSN:1426-9686
[Cp] País de publicação:Poland
[La] Idioma:pol
[Ab] Resumo:Along with the increasing prevalence of obesity surgical methods of treatment are becoming more accessible. The success of bariatric surgery results from the failure of conservative treatment of obesity through diet, exercises and behavioral changes. Such behaviors, including less effective drug therapy, are responsible for rather small and unstable weight reduction. In contrast, surgical treatment restrictions limiting the amount of food intake, excluding treatments and mixed treatments usually give a spectacular effect, though it is not always consistent with the previous assumptions. Most of us, however, do not realize the risk of the consequences that these treatments bring. The change of the absorption of oral medications, vitamins, microelements, often change the way they are metabolized and it forces ones to change the form of the drug, the way they are taken, which undoubtedly is associated with higher costs of later treatment. Many clinicians are unaware of the need for lifelong supplementation of some vitamins and microelements, as well as the need to modify pharmacotherapy in patients who have undergone this type of operations. This article presents examples of the best known and described changes in the absorption of drugs and micronutrients and explains how well oriented the internist ought to be when qualifying a patient to undergo this type of treatment. The described topic is interesting, but also controversial due to the fact that it corresponds closely with the surgical specialties, quite spectacular in their effects and behavioral specializations, that in many years time will be looking after the patient who underwent the surgery, but is still sick.
[Mh] Termos MeSH primário: Cirurgia Bariátrica/efeitos adversos
Síndromes de Malabsorção/etiologia
Micronutrientes/farmacocinética
Obesidade Mórbida/cirurgia
Vitaminas/farmacocinética
[Mh] Termos MeSH secundário: Absorção
Seres Humanos
Obesidade Mórbida/metabolismo
[Pt] Tipo de publicação:ENGLISH ABSTRACT; JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Micronutrients); 0 (Vitamins)
[Em] Mês de entrada:1411
[Cu] Atualização por classe:141027
[Lr] Data última revisão:
141027
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:141028
[St] Status:MEDLINE


  3 / 29082 MEDLINE  
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[PMID]:25194702
[Au] Autor:Hirata S; Totani K; Yamashita T; Adachi C; Vacha M
[Ad] Endereço:Department of Organic and Polymeric Materials, Tokyo Institute of Technology, Meguro, Tokyo 152-8552, Japan.
[Ti] Título:Large reverse saturable absorption under weak continuous incoherent light.
[So] Source:Nat Mater;13(10):938-46, 2014 Oct.
[Is] ISSN:1476-1122
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:In materials showing reverse saturable absorption (RSA), the optical absorbance increases as the power of the light incident on them increases. To date, RSA has only been observed when very intense light sources, such as short-pulse lasers, are used. Here, we show that hydroxyl steroidal matrices embedding properly designed aromatic molecules as acceptors and transition-metal complexes as donors exhibit high RSA on exposure to weak incoherent light at room temperature and in air. Accumulation by photosensitization of long-lived room-temperature triplet excitons in acceptors with a large triplet-triplet absorption coefficient allows a nonlinear increase in absorbance also under low-power irradiation conditions. As a consequence, continuous exposure to weak light significantly decreases the transmittance of thin films fabricated with these compounds. These optical limiting properties may be used to protect eyes and light sensors from exposure to intense radiation generated by incoherent sources and for other light-absorption applications that have not been realized with conventional RSA materials.
[Mh] Termos MeSH primário: Esteroides/química
Esteroides/efeitos da radiação
[Mh] Termos MeSH secundário: Absorção
Estradiol/química
Estradiol/efeitos da radiação
Lasers
Luz
Fenômenos Ópticos
Processos Fotoquímicos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Steroids); 4TI98Z838E (Estradiol)
[Em] Mês de entrada:1411
[Cu] Atualização por classe:171110
[Lr] Data última revisão:
171110
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140908
[St] Status:MEDLINE
[do] DOI:10.1038/nmat4081


  4 / 29082 MEDLINE  
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[PMID]:25185394
[Au] Autor:Barrett TE; Sheesley RJ
[Ti] Título:Urban impacts on regional carbonaceous aerosols: case study in central Texas.
[So] Source:J Air Waste Manag Assoc;64(8):917-26, 2014 Aug.
[Is] ISSN:1096-2247
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Rural and background sites provide valuable information on the concentration and optical properties of organic, elemental, and water-soluble organic carbon (OC, EC, and WSOC), which are relevant for understanding the climate forcing potential of regional atmospheric aerosols. To quantify climate- and air quality-relevant characteristics of carbonaceous aerosol in the central United States, a regional background site in central Texas was chosen for long-term measurement. Back trajectory (BT) analysis, ambient OC, EC, and WSOC concentrations and absorption parameters are reported for the first 15 months of a long-term campaign (May 2011-August 2012). BT analysis indicates consistent north-south airflow connecting central Texas to the Central Plains. Central Texas aerosols exhibited seasonal trends with increased fine particulate matter (< 2.5 microm aerodynamic diameter, PM2.5) and OC during the summer (PM2.5 = 10.9 microg m(-3) and OC = 3.0 microg m(-3)) and elevated EC during the winter (0.22 microg m(-3)). When compared to measurements in Dallas and Houston, TX, central Texas OC appears to have mixed urban and rural sources. However central Texas EC appears to be dominated by transport of urban emissions. WSOC averaged 63% of the annual OC, with little seasonal variability in this ratio. To monitor brown carbon (BrC), absorption was measured for the aqueous WSOC extracts. Light absorption coefficients for EC and BrC were highest during summer (EC MAC = 11 m2 g(-1) and BRC MAE365 = 0.15 m2 g(-1)). Results from optical analysis indicate that regional aerosol absorption is mostly due to EC with summertime peaks in BrC attenuation. This study represents the first reported values of WSOC absorption, MAE365, for the central United States. Implications: Background concentration and absorption measurements are essential in determining regional potential radiative forcing due to atmospheric aerosols. Back trajectory, chemical, and optical analysis of PM2.5 was used to determine climatic and air quality implications of urban outflow to a regional receptor site, representative of the central United States. Results indicate that central Texas organic carbon has mixed urban and rural sources, while elemental carbon is controlled by the transport of urban emissions. Analysis of aerosol absorption showed black carbon as the dominant absorber, with less brown carbon absorption than regional studies in California and the southeastern United States.
[Mh] Termos MeSH primário: Aerossóis/análise
Poluentes Atmosféricos/análise
Carbono/análise
Monitoramento Ambiental
[Mh] Termos MeSH secundário: Absorção
Cidades
Filtração
Tamanho da Partícula
Material Particulado/análise
Estações do Ano
Espectrofotometria Ultravioleta
Texas
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Aerosols); 0 (Air Pollutants); 0 (Particulate Matter); 7440-44-0 (Carbon)
[Em] Mês de entrada:1409
[Cu] Atualização por classe:140904
[Lr] Data última revisão:
140904
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140905
[St] Status:MEDLINE


  5 / 29082 MEDLINE  
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[PMID]:25151280
[Au] Autor:de Abreu FC; da Costa PN; Brondi AM; Pilau EJ; Gozzo FC; Eberlin MN; Trevisan MG; Garcia JS
[Ad] Endereço:LACFar, Institute of Chemistry, Federal University of Alfenas - UNIFAL-MG, Alfenas, Minas Gerais, 37130-000, Brazil.
[Ti] Título:Effects of cadmium and copper biosorption on Chlorella vulgaris.
[So] Source:Bull Environ Contam Toxicol;93(4):405-9, 2014 Oct.
[Is] ISSN:1432-0800
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Changes in protein levels and lipid compositions in algal cells indicate the severity of stress related to toxic concentrations of heavy metals. In this study, the effects of exposure to cadmium and copper on Chlorella vulgaris and its capacity to remove metals were evaluated. The data revealed ion removal activity by microalgae under all treatments and different levels of protein expression after 48 h of exposure. Furthermore, we analyzed lipids contents to characterize them.
[Mh] Termos MeSH primário: Cádmio/metabolismo
Cádmio/toxicidade
Chlorella vulgaris/efeitos dos fármacos
Cobre/toxicidade
[Mh] Termos MeSH secundário: Absorção
Proteínas de Algas/metabolismo
Chlorella vulgaris/metabolismo
Cobre/metabolismo
Metabolismo dos Lipídeos/efeitos dos fármacos
Análise de Componente Principal
Espectrometria de Massas por Ionização e Dessorção a Laser Assistida por Matriz
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Algal Proteins); 00BH33GNGH (Cadmium); 789U1901C5 (Copper)
[Em] Mês de entrada:1411
[Cu] Atualização por classe:140908
[Lr] Data última revisão:
140908
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140825
[St] Status:MEDLINE
[do] DOI:10.1007/s00128-014-1363-x


  6 / 29082 MEDLINE  
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[PMID]:25102050
[Au] Autor:Lee HJ; Aiona PK; Laskin A; Laskin J; Nizkorodov SA
[Ad] Endereço:Department of Chemistry, University of California , Irvine, California 92697, United States.
[Ti] Título:Effect of solar radiation on the optical properties and molecular composition of laboratory proxies of atmospheric brown carbon.
[So] Source:Environ Sci Technol;48(17):10217-26, 2014 Sep 02.
[Is] ISSN:1520-5851
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Sources, optical properties, and chemical composition of atmospheric brown carbon (BrC) aerosol are uncertain, making it challenging to estimate its contribution to radiative forcing. Furthermore, optical properties of BrC may change significantly during its atmospheric aging. We examined the effect of photolysis on the molecular composition, mass absorption coefficient, and fluorescence of secondary organic aerosol (SOA) prepared by high-NOx photooxidation of naphthalene (NAP SOA). Our experiments were designed to model photolysis processes of NAP SOA compounds dissolved in cloud or fog droplets. Aqueous solutions of NAP SOA were observed to photobleach (i.e., lose their ability to absorb visible radiation) with an effective half-life of ∼15 h (with sun in its zenith) for the loss of near-UV (300-400 nm) absorbance. The molecular composition of NAP SOA was significantly modified by photolysis, with the average SOA formula changing from C14.1H14.5O5.1N0.085 to C11.8H14.9O4.5N0.023 after 4 h of irradiation. However, the average O/C ratio did not change significantly, suggesting that it is not a good metric for assessing the extent of photolysis-driven aging in NAP SOA (and in BrC in general). In contrast to NAP SOA, the photobleaching of BrC material produced by the reaction of limonene + ozone SOA with ammonia vapor (aged LIM/O3 SOA) was much faster, but it did not result in a significant change in average molecular composition. The characteristic absorbance of the aged LIM/O3 SOA in the 450-600 nm range decayed with an effective half-life of <0.5 h. These results emphasize the highly variable and dynamic nature of different types of atmospheric BrC.
[Mh] Termos MeSH primário: Atmosfera/química
Carbono/química
Laboratórios
Fenômenos Ópticos
Luz Solar
[Mh] Termos MeSH secundário: Absorção
Aerossóis/química
Cicloexenos/química
Meia-Vida
Espectrometria de Massas
Peso Molecular
Naftalenos/química
Compostos Orgânicos/química
Oxirredução
Fotólise/efeitos da radiação
Soluções
Espectrometria de Fluorescência
Espectrofotometria Ultravioleta
Terpenos/química
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, U.S. GOV'T, NON-P.H.S.
[Nm] Nome de substância:
0 (Aerosols); 0 (Cyclohexenes); 0 (Naphthalenes); 0 (Organic Chemicals); 0 (Solutions); 0 (Terpenes); 2166IN72UN (naphthalene); 7440-44-0 (Carbon); 9MC3I34447 (limonene)
[Em] Mês de entrada:1410
[Cu] Atualização por classe:140902
[Lr] Data última revisão:
140902
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140808
[St] Status:MEDLINE
[do] DOI:10.1021/es502515r


  7 / 29082 MEDLINE  
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[PMID]:25095389
[Au] Autor:Le Z; Zhao XL; Di LQ
[Ti] Título:[Absorption and transportation of calycosin in Astragali Radix by using Caco-2 monolayer model].
[So] Source:Zhongguo Zhong Yao Za Zhi;39(9):1709-13, 2014 May.
[Is] ISSN:1001-5302
[Cp] País de publicação:China
[La] Idioma:chi
[Ab] Resumo:Flavonoids are a class of important active ingredients in traditional Chinese medicine, pharmacological activity and in vivo process is the focus of research in recent years. Calycosin is the main active ingredients of flavonoids in Astragali Radix, recent studies indicate that it has many kinds of pharmacological activity, but the absorption and transport characteristics in vivo is unclear. The experiment using Caco-2 cell model, with apigenin as internal standard substance, using the method for the determination of drug concentration by HPLC, were studied at different concentrations and absorption transport characteristics of respectively adding different types of protein inhibitors. Data were analyzed by Q test, the results show that low, middle, high concentration of P(app)(BL-AP)/ P(app)(AP-BL) = 1.38 < 1.5, respectively adding different types of protein inhibitors, compared with the control group of P(app)(BL-AP)/ P(app)(AP-BL), there were no significant differences. Calycosin absorption may mainly passive transport, also involved in active transport mechanism, the transport may not be affected by the P-protein, MRP2 protein, SGLT protein.
[Mh] Termos MeSH primário: Medicamentos de Ervas Chinesas/farmacocinética
Isoflavonas/farmacocinética
Modelos Biológicos
[Mh] Termos MeSH secundário: Absorção
Transporte Biológico
Células CACO-2
Cromatografia Líquida de Alta Pressão
Meios de Cultivo Condicionados/química
Estabilidade de Medicamentos
Medicamentos de Ervas Chinesas/análise
Seres Humanos
Concentração de Íons de Hidrogênio
Isoflavonas/análise
[Pt] Tipo de publicação:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Astragali compound); 0 (Culture Media, Conditioned); 0 (Drugs, Chinese Herbal); 0 (Isoflavones); 09N3E8P7TA (7,3'-dihydroxy-4'-methoxyisoflavone)
[Em] Mês de entrada:1410
[Cu] Atualização por classe:140806
[Lr] Data última revisão:
140806
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140807
[St] Status:MEDLINE


  8 / 29082 MEDLINE  
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[PMID]:25048944
[Au] Autor:Owsianiak M; Veltman K; Hauschild MZ; Hendriks AJ; Steinmann ZJ; Huijbregts MA
[Ad] Endereço:Division for Quantitative Sustainability Assessment, Department of Management Engineering, Technical University of Denmark, Produktionstorvet, Building 426, DK-2800 Kgs. Lyngby, Denmark. Electronic address: miow@dtu.dk.
[Ti] Título:Elucidating differences in metal absorption efficiencies between terrestrial soft-bodied and aquatic species.
[So] Source:Chemosphere;112:487-95, 2014 Oct.
[Is] ISSN:1879-1298
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:It is unknown whether metal absorption efficiencies in terrestrial soft-bodied species can be predicted with the same metal properties as for aquatic species. Here, we developed models for metal absorption efficiency from the dissolved phase for terrestrial worms and several aquatic species, based on 23 metal physicochemical properties. For the worms, the absorption efficiency was successfully related to 7 properties, and is best predicted with the ionic potential. Different properties (8 in total) were found to be statistically significant in regressions predicting metal absorption in aquatic species, with the covalent index being the best predictor. It is hypothesized that metal absorption by soft-bodied species in soil systems is influenced by the rate of metal supply to the membrane, while in aquatic systems accumulation is solely determined by metal affinity to membrane bound transport proteins. Our results imply that developing predictive terrestrial bioaccumulation and toxicity models for metals must consider metal interactions with soil solids. This may include desorption of a cation bound to soil solids through ion exchange, or metal release from soil surfaces involving breaking of metal-oxygen bonds.
[Mh] Termos MeSH primário: Organismos Aquáticos/metabolismo
Metais/metabolismo
Oligoquetos/metabolismo
Poluentes do Solo/metabolismo
[Mh] Termos MeSH secundário: Absorção
Animais
Modelos Biológicos
Solo/química
Especificidade da Espécie
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Metals); 0 (Soil); 0 (Soil Pollutants)
[Em] Mês de entrada:1410
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140723
[St] Status:MEDLINE


  9 / 29082 MEDLINE  
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[PMID]:25048923
[Au] Autor:Patel A; Patra DD
[Ad] Endereço:Agronomy and Soil Science, Central Institute of Medicinal and Aromatic Plants, Lucknow 226015, India. Electronic address: patel7anju@gmail.com.
[Ti] Título:Influence of heavy metal rich tannery sludge on soil enzymes vis-à-vis growth of Tagetes minuta, an essential oil bearing crop.
[So] Source:Chemosphere;112:323-32, 2014 Oct.
[Is] ISSN:1879-1298
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Tannery sludge is available in plenty and is hazardous to environment as well as plant and animal life. It is very important to manage the tannery sludge in an environmentally sound manner. The aim of this study was to assess the physico-chemical, microbial and biochemical properties of soil treated with different levels of sludge. In this study, Tagetes minuta an essential oil bearing crop was grown in two different textured soils treated with different levels of tannery sludge. Application of tannery sludge (TS) increased the growth and oil yield of plant and also the activity of urease and soil microbial biomass nitrogen (SMBN) when applied in 50:50 combinations of soil:sludge. The crop performed well in coarse soil with a soil:sludge ratio of 50:50. High concentration of tannery sludge exhibited inhibitory effect on SMBN and urease activity. Acid/alkaline phosphatase, dehydrogenase and soil microbial biomass carbon (SMBC) increased as the sludge concentration increased in soil. This may be due to high organic matter present in tannery sludge. Roots accumulated more metal than the shoot. No detectable amount of metal was found in oil of T.minuta. To test the relation between 20 characters principal component analysis (PCA) was performed. PCA analysis indicates that cation exchange capacity (CEC), SMBC, dehydrogenase, acid and alkaline phosphatases were grouped in group 1. SMBN, urease and cis-ocimene content in oil were in group 2 whereas biomasss, chlorophyll a, limonene, Z and E-tagetone were in group 3. PC-I contributes 54% of total variance and PC-II contributes 38% of the total variance. The results concluded that T.minuta can mitigate metal toxicity by root absorption. Microbial activity and biomass of plant was higher in coarse soil with TS than fine soil with TS.
[Mh] Termos MeSH primário: Metais Pesados/toxicidade
Óleos Voláteis/metabolismo
Esgotos/química
Poluentes do Solo/toxicidade
Solo/química
Tagetes/efeitos dos fármacos
Tagetes/crescimento & desenvolvimento
[Mh] Termos MeSH secundário: Absorção
Animais
Biodegradação Ambiental
Transporte Biológico
Biomassa
Clorofila/metabolismo
Produtos Agrícolas/efeitos dos fármacos
Produtos Agrícolas/crescimento & desenvolvimento
Produtos Agrícolas/metabolismo
Metais Pesados/isolamento & purificação
Metais Pesados/metabolismo
Fosfatidilcolinas/metabolismo
Raízes de Plantas/efeitos dos fármacos
Raízes de Plantas/crescimento & desenvolvimento
Poluentes do Solo/isolamento & purificação
Poluentes do Solo/metabolismo
Tagetes/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Metals, Heavy); 0 (Oils, Volatile); 0 (Phosphatidylcholines); 0 (Sewage); 0 (Soil); 0 (Soil Pollutants); 1406-65-1 (Chlorophyll); 65114-55-8 (1-palmitoyl-2-omega-(2-diazo-3,3,3-trifluoropropionyloxy)lauroyl-sn-glycero-3-phosphocholine); YF5Q9EJC8Y (chlorophyll a)
[Em] Mês de entrada:1410
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140723
[St] Status:MEDLINE


  10 / 29082 MEDLINE  
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[PMID]:25016649
[Au] Autor:Mohsin SM; Hussein MZ; Sarijo SH; Fakurazi S; Arulselvan P; Taufiq-Yap YH
[Ti] Título:Optimization of UV absorptivity of layered double hydroxide by intercalating organic UV-absorbent molecules.
[So] Source:J Biomed Nanotechnol;10(8):1490-500, 2014 Aug.
[Is] ISSN:1550-7033
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Intercalation of Zn/Al layered double hydroxide (LDH) with benzophenone 9 (B9), a strong ultraviolet (UV) absorber, had been carried out by two different routes; co-precipitation and ion exchange method. Powder X-ray diffraction (PXRD) patterns of co-precipitated (ZB9C) and ion exchanged product (ZB91) showed basal spacing of 15.9 angstrom and 16.6 angstrom, respectively, as a result of the intercalation of B9 anions into the lamellae spaces of LDH. Intercalation was further confirmed by Fourier transform infrared spectra (FTIR), carbon, hydrogen, nitrogen and sulfur (CHNS) and thermogravimetric and differential thermogravimetric (TGA/DTG) studies. UV-vis absorption properties of the nanocomposite was investigated with diffuse reflectance UV-visible spectrometer and showed broader UV absorption range. Furthermore, stability of sunscreen molecules in LDH interlayer space was tested in deionized water, artificial sea water and skin pH condition to show slow deintercalation and high retention in host. Cytotoxicity study of the synthesized nanocomposites on human dermal fibroblast (HDF) cells shows no significant cytotoxicity after 24 h exposure for test concentrations up to 25 microg/mL.
[Mh] Termos MeSH primário: Hidróxido de Alumínio/química
Hidróxidos/química
Nanocompostos/química
Protetores Solares/química
Compostos de Zinco/química
[Mh] Termos MeSH secundário: Absorção
Hidróxido de Alumínio/toxicidade
Benzofenonas/química
Benzofenonas/farmacocinética
Linhagem Celular
Sobrevivência Celular/efeitos dos fármacos
Seres Humanos
Hidróxidos/toxicidade
Nanocompostos/toxicidade
Análise Espectral
Protetores Solares/farmacocinética
Raios Ultravioleta
Compostos de Zinco/toxicidade
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Benzophenones); 0 (Hydroxides); 0 (Sunscreening Agents); 0 (Zinc Compounds); 5QB0T2IUN0 (Aluminum Hydroxide); OXK3V8KJ7L (zinc hydroxide)
[Em] Mês de entrada:1408
[Cu] Atualização por classe:140714
[Lr] Data última revisão:
140714
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140715
[St] Status:MEDLINE



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BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde