Base de dados : MEDLINE
Pesquisa : G01.060.075.730.700.412 [Categoria DeCS]
Referências encontradas : 279 [refinar]
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  1 / 279 MEDLINE  
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[PMID]:28332539
[Au] Autor:Reardon S; Tollefson J; Witze A; Ross E
[Ti] Título:US science agencies face deep cuts in Trump budget.
[So] Source:Nature;543(7646):471-472, 2017 03 16.
[Is] ISSN:1476-4687
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Orçamentos/legislação & jurisprudência
National Institutes of Health (U.S.)/economia
Ciência/economia
Ciência/legislação & jurisprudência
United States Environmental Protection Agency/economia
United States National Aeronautics and Space Administration/economia
[Mh] Termos MeSH secundário: Animais
Seres Humanos
Júpiter
Planetas Menores
National Institutes of Health (U.S.)/organização & administração
Ciência/tendências
Estados Unidos
[Pt] Tipo de publicação:NEWS
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170804
[Lr] Data última revisão:
170804
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170324
[St] Status:MEDLINE
[do] DOI:10.1038/nature.2017.21652


  2 / 279 MEDLINE  
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[PMID]:27558045
[Au] Autor:Witze A
[Ti] Título:Obama's science legacy: a space race stalls.
[So] Source:Nature;536(7617):386, 2016 08 25.
[Is] ISSN:1476-4687
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Governo Federal
Marte
Política
Voo Espacial/legislação & jurisprudência
Voo Espacial/tendências
United States National Aeronautics and Space Administration/legislação & jurisprudência
[Mh] Termos MeSH secundário: Astronautas/economia
Astronautas/tendências
Seres Humanos
Júpiter
Planetas Menores
Robótica/economia
Robótica/tendências
Voo Espacial/economia
Voo Espacial/instrumentação
Estados Unidos
United States National Aeronautics and Space Administration/economia
United States National Aeronautics and Space Administration/tendências
[Pt] Tipo de publicação:NEWS
[Em] Mês de entrada:1609
[Cu] Atualização por classe:161216
[Lr] Data última revisão:
161216
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160826
[St] Status:MEDLINE
[do] DOI:10.1038/536386a


  3 / 279 MEDLINE  
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[PMID]:27552160
[Au] Autor:Nadeau J; Lindensmith C; Deming JW; Fernandez VI; Stocker R
[Ad] Endereço:1 GALCIT, California Institute of Technology , Pasadena, California.
[Ti] Título:Microbial Morphology and Motility as Biosignatures for Outer Planet Missions.
[So] Source:Astrobiology;16(10):755-774, 2016 Oct.
[Is] ISSN:1557-8070
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Meaningful motion is an unambiguous biosignature, but because life in the Solar System is most likely to be microbial, the question is whether such motion may be detected effectively on the micrometer scale. Recent results on microbial motility in various Earth environments have provided insight into the physics and biology that determine whether and how microorganisms as small as bacteria and archaea swim, under which conditions, and at which speeds. These discoveries have not yet been reviewed in an astrobiological context. This paper discusses these findings in the context of Earth analog environments and environments expected to be encountered in the outer Solar System, particularly the jovian and saturnian moons. We also review the imaging technologies capable of recording motility of submicrometer-sized organisms and discuss how an instrument would interface with several types of sample-collection strategies. Key Words: In situ measurement-Biosignatures-Microbiology-Europa-Ice. Astrobiology 16, 755-774.
[Mh] Termos MeSH primário: Archaea/citologia
Bactérias/citologia
Exobiologia/métodos
Meio Ambiente Extraterreno
Voo Espacial
[Mh] Termos MeSH secundário: Corrente Citoplasmática
Terra (Planeta)
Camada de Gelo/microbiologia
Júpiter
Microscopia
Oceanos e Mares
Saturno
Microbiologia da Água
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170926
[Lr] Data última revisão:
170926
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160824
[St] Status:MEDLINE


  4 / 279 MEDLINE  
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[PMID]:27054695
[Au] Autor:Frydkjaer-Olsen U; Soegaard Hansen R; Simó R; Cunha-Vaz J; Peto T; Grauslund J; EUROCONDOR
[Ad] Endereço:Department of Ophthalmology, Odense University Hospital, Odense, Denmark.
[Ti] Título:Correlation between Retinal Vessel Calibre and Neurodegeneration in Patients with Type 2 Diabetes Mellitus in the European Consortium for the Early Treatment of Diabetic Retinopathy (EUROCONDOR).
[So] Source:Ophthalmic Res;56(1):10-6, 2016.
[Is] ISSN:1423-0259
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:PURPOSE: To investigate the correlation between retinal vessel calibre and measurements of neurodegeneration in patients with type 2 diabetes (T2D) and no or early diabetic retinopathy (DR). METHODS: Baseline data on 440 patients with T2D from the EUROCONDOR clinical trial were used. DR was graded according to the Early Treatment of Diabetic Retinopathy Study (ETDRS) scale, and patients with ETDRS levels 10-35 were included. Retinal vessel diameters were measured by semi-automatic software. Calibres were summarized into central retinal artery and vein equivalents (CRAE and CRVE). RESULTS: Median age and diabetes duration were 64.0 and 10.3 years, respectively. ETDRS levels were 10 (42.3%), 20 (27.5%) and 35 (30.2%). The median CRAE and CRVE were 146.7 and 215.3 µm, respectively. CRAE did not differ according to ETRDS level (p = 0.12), but wider CRVE were found in patients with higher ETDRS levels (p = 0.04). In a multivariable linear regression model, CRAE was associated with macular ganglion cell layer thickness (coefficient 0.27 per micrometre, p < 0.01), and CRVE was correlated with macular retinal thickness (coefficient -0.07 per micrometre, p = 0.04) and retinal nerve fibre layer thickness at the optic disc (coefficient 0.32 per micrometre, p < 0.01). CONCLUSION: Retinal vessel calibre was independently associated with structural changes of the neuroretina in patients with no or early DR.
[Mh] Termos MeSH primário: Tartarato de Brimonidina/administração & dosagem
Diabetes Mellitus Tipo 2/complicações
Retinopatia Diabética/complicações
Degeneração Retiniana/diagnóstico
Vasos Retinianos/patologia
Somatostatina/administração & dosagem
[Mh] Termos MeSH secundário: Agonistas de Receptores Adrenérgicos alfa 2/uso terapêutico
Idoso
Diabetes Mellitus Tipo 2/diagnóstico
Retinopatia Diabética/diagnóstico
Retinopatia Diabética/tratamento farmacológico
Quimioterapia Combinada
Eletrorretinografia
Feminino
Seguimentos
Hormônios/uso terapêutico
Seres Humanos
Júpiter
Masculino
Meia-Idade
Fármacos Neuroprotetores/administração & dosagem
Soluções Oftálmicas
Estudos Prospectivos
Degeneração Retiniana/etiologia
Degeneração Retiniana/prevenção & controle
Células Ganglionares da Retina/patologia
Fatores de Tempo
Tomografia de Coerência Óptica/métodos
Resultado do Tratamento
[Pt] Tipo de publicação:CLINICAL TRIAL, PHASE II; CLINICAL TRIAL, PHASE III; JOURNAL ARTICLE; MULTICENTER STUDY; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Adrenergic alpha-2 Receptor Agonists); 0 (Hormones); 0 (Neuroprotective Agents); 0 (Ophthalmic Solutions); 4S9CL2DY2H (Brimonidine Tartrate); 51110-01-1 (Somatostatin)
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170131
[Lr] Data última revisão:
170131
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160408
[St] Status:MEDLINE
[do] DOI:10.1159/000444396


  5 / 279 MEDLINE  
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[PMID]:27000678
[Au] Autor:Scientific Exchanges Committee (currently Global Committee)
[Ti] Título:[Report of ECR 2015].
[So] Source:Nihon Hoshasen Gijutsu Gakkai Zasshi;72(3):290-4, 2016 Mar.
[Is] ISSN:0369-4305
[Cp] País de publicação:Japan
[La] Idioma:jpn
[Mh] Termos MeSH primário: Congressos como Assunto
Radiologia/organização & administração
Sociedades Científicas/organização & administração
[Mh] Termos MeSH secundário: Júpiter
[Pt] Tipo de publicação:CONGRESSES
[Em] Mês de entrada:1606
[Cu] Atualização por classe:160322
[Lr] Data última revisão:
160322
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160323
[St] Status:MEDLINE
[do] DOI:10.6009/jjrt.2016_JSRT_72.3.290


  6 / 279 MEDLINE  
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[PMID]:26738570
[Au] Autor:Gibney E
[Ti] Título:The science to look out for in 2016.
[So] Source:Nature;529(7584):14-5, 2016 Jan 07.
[Is] ISSN:1476-4687
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Ciência/tendências
Sono/genética
[Mh] Termos MeSH secundário: Animais
Atmosfera/química
Dióxido de Carbono/economia
Dióxido de Carbono/isolamento & purificação
Ensaios Clínicos como Assunto
Hemofilia A/genética
Hemofilia A/terapia
Seres Humanos
Júpiter
Marte
Microbiota
Neurociências
Fenômenos Físicos
Política
Comunicações Via Satélite
Astronave
Síncrotrons
Fenômenos Fisiológicos Virais
Talassemia beta/genética
Talassemia beta/terapia
[Pt] Tipo de publicação:NEWS
[Nm] Nome de substância:
142M471B3J (Carbon Dioxide)
[Em] Mês de entrada:1601
[Cu] Atualização por classe:160107
[Lr] Data última revisão:
160107
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160108
[St] Status:MEDLINE
[do] DOI:10.1038/529014a


  7 / 279 MEDLINE  
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[PMID]:26701303
[Au] Autor:Grazier KR
[Ad] Endereço:Jet Propulsion Laboratory, California Institute of Technology , Pasadena, California.
[Ti] Título:Jupiter: Cosmic Jekyll and Hyde.
[So] Source:Astrobiology;16(1):23-38, 2016 Jan.
[Is] ISSN:1557-8070
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:It has been widely reported that Jupiter has a profound role in shielding the terrestrial planets from comet impacts in the Solar System, and that a jovian planet is a requirement for the evolution of life on Earth. To evaluate whether jovians, in fact, shield habitable planets from impacts (a phenomenon often referred to as the "Jupiter as shield" concept), this study simulated the evolution of 10,000 particles in each of the jovian inter-planet gaps for the cases of full-mass and embryo planets for up to 100 My. The results of these simulations predict a number of phenomena that not only discount the "Jupiter as shield" concept, they also predict that in a Solar System like ours, large gas giants like Saturn and Jupiter had a different, and potentially even more important, role in the evolution of life on our planet by delivering the volatile-laden material required for the formation of life. The simulations illustrate that, although all particles occupied "non-life threatening" orbits at their onset of the simulations, a significant fraction of the 30,000 particles evolved into Earth-crossing orbits. A comparison of multiple runs with different planetary configurations revealed that Jupiter was responsible for the vast majority of the encounters that "kicked" outer planet material into the terrestrial planet region, and that Saturn assisted in the process far more than has previously been acknowledged. Jupiter also tends to "fix" the aphelion of planetesimals at its orbit irrespective of their initial starting zones, which has the effect of slowing their passages through the inner Solar System, and thus potentially improving the odds of accretion of cometary material by terrestrial planets. As expected, the simulations indicate that the full-mass planets perturb many objects into the deep outer Solar System, or eject them entirely; however, planetary embryos also did this with surprising efficiency. Finally, the simulations predict that Jupiter's capacity to shield or intercept Earth-bound comets originating in the outer Solar System is poor, and that the importance of jovian planets on the formation of life is not that they act as shields, but rather that they deliver life-enabling volatiles to the terrestrial planets.
[Mh] Termos MeSH primário: Júpiter
[Mh] Termos MeSH secundário: Simulação por Computador
Evolução Planetária
Saturno
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, U.S. GOV'T, NON-P.H.S.
[Em] Mês de entrada:1610
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151225
[St] Status:MEDLINE
[do] DOI:10.1089/ast.2015.1321


  8 / 279 MEDLINE  
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[PMID]:26675732
[Au] Autor:Sing DK; Fortney JJ; Nikolov N; Wakeford HR; Kataria T; Evans TM; Aigrain S; Ballester GE; Burrows AS; Deming D; Désert JM; Gibson NP; Henry GW; Huitson CM; Knutson HA; des Etangs AL; Pont F; Showman AP; Vidal-Madjar A; Williamson MH; Wilson PA
[Ad] Endereço:Astrophysics Group, School of Physics, University of Exeter, Stocker Road, Exeter EX4 4QL, UK.
[Ti] Título:A continuum from clear to cloudy hot-Jupiter exoplanets without primordial water depletion.
[So] Source:Nature;529(7584):59-62, 2016 Jan 07.
[Is] ISSN:1476-4687
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Thousands of transiting exoplanets have been discovered, but spectral analysis of their atmospheres has so far been dominated by a small number of exoplanets and data spanning relatively narrow wavelength ranges (such as 1.1-1.7 micrometres). Recent studies show that some hot-Jupiter exoplanets have much weaker water absorption features in their near-infrared spectra than predicted. The low amplitude of water signatures could be explained by very low water abundances, which may be a sign that water was depleted in the protoplanetary disk at the planet's formation location, but it is unclear whether this level of depletion can actually occur. Alternatively, these weak signals could be the result of obscuration by clouds or hazes, as found in some optical spectra. Here we report results from a comparative study of ten hot Jupiters covering the wavelength range 0.3-5 micrometres, which allows us to resolve both the optical scattering and infrared molecular absorption spectroscopically. Our results reveal a diverse group of hot Jupiters that exhibit a continuum from clear to cloudy atmospheres. We find that the difference between the planetary radius measured at optical and infrared wavelengths is an effective metric for distinguishing different atmosphere types. The difference correlates with the spectral strength of water, so that strong water absorption lines are seen in clear-atmosphere planets and the weakest features are associated with clouds and hazes. This result strongly suggests that primordial water depletion during formation is unlikely and that clouds and hazes are the cause of weaker spectral signatures.
[Mh] Termos MeSH primário: Atmosfera/química
Meio Ambiente Extraterreno/química
Planetas
Água/análise
[Mh] Termos MeSH secundário: Júpiter
Pressão
Espectrofotometria Infravermelho
Telescópios
Temperatura Ambiente
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T; RESEARCH SUPPORT, U.S. GOV'T, NON-P.H.S.
[Nm] Nome de substância:
059QF0KO0R (Water)
[Em] Mês de entrada:1601
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151218
[St] Status:MEDLINE
[do] DOI:10.1038/nature16068


  9 / 279 MEDLINE  
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[PMID]:26349132
[Au] Autor:Billings L
[Ti] Título:Europa's "Brown Gunk" Suggests a Briny Sea.
[So] Source:Sci Am;313(2):19, 2015 Aug.
[Is] ISSN:0036-8733
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Júpiter
Oceanos e Mares
[Mh] Termos MeSH secundário: Estados Unidos
United States National Aeronautics and Space Administration
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1511
[Cu] Atualização por classe:150908
[Lr] Data última revisão:
150908
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150910
[St] Status:MEDLINE


  10 / 279 MEDLINE  
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[PMID]:26060983
[Au] Autor:Loeffler MJ; Hudson RL
[Ad] Endereço:Astrochemistry Laboratory, NASA Goddard Space Flight Center , Greenbelt, Maryland.
[Ti] Título:Descent without Modification? The Thermal Chemistry of H2O2 on Europa and Other Icy Worlds.
[So] Source:Astrobiology;15(6):453-61, 2015 Jun.
[Is] ISSN:1557-8070
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The strong oxidant H2O2 is known to exist in solid form on Europa and is suspected to exist on several other Solar System worlds at temperatures below 200 K. However, little is known of the thermal chemistry that H2O2 might induce under these conditions. Here, we report new laboratory results on the reactivity of solid H2O2 with eight different compounds in H2O-rich ices. Using infrared spectroscopy, we monitored compositional changes in ice mixtures during warming. The compounds CH4 (methane), C3H4 (propyne), CH3OH (methanol), and CH3CN (acetonitrile) were unaltered by the presence of H2O2 in ices, showing that exposure to either solid H2O2 or frozen H2O+H2O2 at cryogenic temperatures will not oxidize these organics, much less convert them to CO2. This contrasts strongly with the much greater reactivity of organics with H2O2 at higher temperatures, and particularly in the liquid and gas phases. Of the four inorganic compounds studied, CO, H2S, NH3, and SO2, only the last two reacted in ices containing H2O2, NH3 making NH4+ and SO2 making SO(4)2- by H+ and e- transfer, respectively. An important astrobiological conclusion is that formation of surface H2O2 on Europa and that molecule's downward movement with H2O-ice do not necessarily mean that all organics encountered in icy subsurface regions will be destroyed by H2O2 oxidation.
[Mh] Termos MeSH primário: Peróxido de Hidrogênio/química
Gelo
Júpiter
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Ice); BBX060AN9V (Hydrogen Peroxide)
[Em] Mês de entrada:1603
[Cu] Atualização por classe:150611
[Lr] Data última revisão:
150611
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150611
[St] Status:MEDLINE
[do] DOI:10.1089/ast.2014.1195



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