Base de dados : MEDLINE
Pesquisa : G01.750.750.055 [Categoria DeCS]
Referências encontradas : 2424 [refinar]
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  1 / 2424 MEDLINE  
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[PMID]:27771446
[Au] Autor:Wood V; Ackerman NL
[Ad] Endereço:Department of Physics and Astronomy, Agnes Scott College, 141 E College Ave, Decatur, GA, 30030 United States.
[Ti] Título:Cherenkov light production from the α-emitting decay chains of Ra, Pb, and Tb for Cherenkov Luminescence Imaging.
[So] Source:Appl Radiat Isot;118:354-360, 2016 Dec.
[Is] ISSN:1872-9800
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Cherenkov Luminescence Imaging (CLI) is a new method to image radioactive therapeutic and diagnostic agents, primarily in preclinical studies. This study used Geant4 and Python to generate the predicted Cherenkov light production as a function of time for a set of isotopic chains of interest for targeted alpha therapy: Ra, Pb, and Tb. All are shown to produce substantial Cherenkov light, though time delays between initial decays and the production of Cherenkov light requires caution in interpreting CLI.
[Mh] Termos MeSH primário: Partículas alfa
Radioisótopos de Chumbo/química
Luz
Medições Luminescentes/métodos
Modelos Químicos
Rádio (Elemento)/química
Térbio/química
[Mh] Termos MeSH secundário: Simulação por Computador
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Lead Radioisotopes); 0 (Radium-223); 06SSF7P179 (Terbium); W90AYD6R3Q (Radium)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180208
[Lr] Data última revisão:
180208
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161025
[St] Status:MEDLINE


  2 / 2424 MEDLINE  
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[PMID]:29328944
[Au] Autor:Sáez-Muñoz M; Bas MDC; Ortiz J; Martorell S
[Ad] Endereço:Laboratorio de Radiactividad Ambiental, MEDASEGI Research Group, Universitat Politècnica de València, Spain. Electronic address: masaemuo@etsii.upv.es.
[Ti] Título:Analysis of the evolution of gross alpha and gross beta activities in airborne samples in Valencia (Spain).
[So] Source:J Environ Radioact;183:94-101, 2018 Mar.
[Is] ISSN:1879-1700
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Gross alpha (A ) and gross beta activities (A ) were measured weekly in the airborne of the Universitat Politècnica de Valencia campus (in the east of Spain) during the period 2009-2015 (7 years). The geometric mean values of weekly A and A were 0.53·10 Bq m and 5.77·10 Bq m , respectively; with an average ratio A /A of 0.097. This study highlights the heterogeneity of gross alpha and gross beta activities depending on the different periods of the year. Data show seasonal variations with the highest activity in summer months and the lowest one in winter months. Several atmospheric factors were considered in order to explain this intra-annual variation (wind speed, temperature, relative humidity, precipitations, dust content and prevailing wind directions). Multiple Linear Regression Analysis were performed in order to obtain information on significant atmospheric factors that affect gross α and gross ß variability, which could be useful in identifying meteorological or atmospheric changes that could cause deviations in gross α and gross ß activity depending on the seasons considered. Models obtained explain more than 60% of variability for global data, and also for winter and spring-autumn months. However, more research is needed to explain gross α and gross ß variability in summer months, because the atmospheric factors considered in the MLR explain less than 35% of variability.
[Mh] Termos MeSH primário: Poluentes Radioativos do Ar/análise
Partículas alfa
Partículas beta
Monitoramento de Radiação
[Mh] Termos MeSH secundário: Umidade
Espanha
Temperatura Ambiente
Vento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Air Pollutants, Radioactive)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180130
[Lr] Data última revisão:
180130
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180113
[St] Status:MEDLINE


  3 / 2424 MEDLINE  
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[PMID]:29023595
[Au] Autor:Lamart S; Miller BW; Van der Meeren A; Tazrart A; Angulo JF; Griffiths NM
[Ad] Endereço:Laboratoire de RadioToxicologie, CEA, Université Paris-Saclay, Arpajon, France.
[Ti] Título:Actinide bioimaging in tissues: Comparison of emulsion and solid track autoradiography techniques with the iQID camera.
[So] Source:PLoS One;12(10):e0186370, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:This work presents a comparison of three autoradiography techniques for imaging biological samples contaminated with actinides: emulsion-based, plastic-based autoradiography and a quantitative digital technique, the iQID camera, based on the numerical analysis of light from a scintillator screen. In radiation toxicology it has been important to develop means of imaging actinide distribution in tissues as these radionuclides may be heterogeneously distributed within and between tissues after internal contamination. Actinide distribution determines which cells are exposed to alpha radiation and is thus potentially critical for assessing absorbed dose. The comparison was carried out by generating autoradiographs of the same biological samples contaminated with actinides with the three autoradiography techniques. These samples were cell preparations or tissue sections collected from animals contaminated with different physico-chemical forms of actinides. The autoradiograph characteristics and the performances of the techniques were evaluated and discussed mainly in terms of acquisition process, activity distribution patterns, spatial resolution and feasibility of activity quantification. The obtained autoradiographs presented similar actinide distribution at low magnification. Out of the three techniques, emulsion autoradiography is the only one to provide a highly-resolved image of the actinide distribution inherently superimposed on the biological sample. Emulsion autoradiography is hence best interpreted at higher magnifications. However, this technique is destructive for the biological sample. Both emulsion- and plastic-based autoradiography record alpha tracks and thus enabled the differentiation between ionized forms of actinides and oxide particles. This feature can help in the evaluation of decorporation therapy efficacy. The most recent technique, the iQID camera, presents several additional features: real-time imaging, separate imaging of alpha particles and gamma rays, and alpha activity quantification. The comparison of these three autoradiography techniques showed that they are complementary and the choice of the technique depends on the purpose of the imaging experiment.
[Mh] Termos MeSH primário: Autorradiografia/métodos
[Mh] Termos MeSH secundário: Elementos da Série Actinoide/química
Partículas alfa
Animais
Autorradiografia/instrumentação
Pulmão/patologia
Músculo Esquelético/patologia
Ratos
Pele/patologia
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Actinoid Series Elements)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171024
[Lr] Data última revisão:
171024
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171013
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0186370


  4 / 2424 MEDLINE  
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[PMID]:28961584
[Au] Autor:Misdaq MA; Elouardi B; Ouguidi J
[Ad] Endereço:*Nuclear Physics and Techniques Laboratory, Faculty of Sciences Semlalia, BP.2390, University of Cadi Ayyad, Marrakech, Morocco (URAC-15 Research Unit Associated to the CNRST, Rabat, Morocco).
[Ti] Título:222Rn, 220Rn and Their Progenies Measured in the Air of Different Dwellings and Workplaces and Resulting Alpha Radiation Doses to the Eyes of Individuals.
[So] Source:Health Phys;113(5):363-374, 2017 Nov.
[Is] ISSN:1538-5159
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:In order to assess radiation doses to the eyes of individuals, concentrations of Rn, Rn and their decay products were measured in different dwelling rooms, café rooms and vehicle repair shops by using two different types of solid state nuclear track detectors (SSNTDs). The influence of building materials, pollution and ventilation rate on radon and thoron alpha-activities inside the studied locations has been investigated. A new dosimetric model was developed for evaluating radiation doses to the eyes of individuals due to alpha particles emitted by the radon and thoron series in the air of the studied dwelling rooms, café rooms, and vehicle repair shops. The influence of the radon and thoron activities in the air of the studied locations, as well as exposure time on committed equivalent dose to the eyes of individuals, was investigated. A maximum value of the committed equivalent dose to the eyes of individuals due to alpha particles emitted by the radon and thoron series was found equal to 0.1 mSv y cm. Committed equivalent dose to the eyes of individuals due to the diffusion of the Rn and Rn gases present in ambient air of the studied locations has been evaluated.
[Mh] Termos MeSH primário: Partículas alfa
Olho/efeitos da radiação
Habitação
Exposição Ocupacional/análise
Radônio/análise
Radônio/química
Local de Trabalho
[Mh] Termos MeSH secundário: Poluição do Ar em Ambientes Fechados/análise
Difusão
Seres Humanos
Radioquímica
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
Q74S4N8N1G (Radon)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171010
[Lr] Data última revisão:
171010
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170930
[St] Status:MEDLINE
[do] DOI:10.1097/HP.0000000000000710


  5 / 2424 MEDLINE  
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[PMID]:28864619
[Au] Autor:Müller C; van der Meulen NP; Benesová M; Schibli R
[Ad] Endereço:Center for Radiopharmaceutical Sciences ETH-PSI-USZ, Paul Scherrer Institut, Villigen-PSA, Switzerland.
[Ti] Título:Therapeutic Radiometals Beyond Lu and Y: Production and Application of Promising α-Particle, ß -Particle, and Auger Electron Emitters.
[So] Source:J Nucl Med;58(Suppl 2):91S-96S, 2017 Sep.
[Is] ISSN:1535-5667
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:In recent years, new α-particle-, ß -particle-, and Auger electron-emitting radiometals-such as Cu, Sc, Ho, Tb, Tb, Pb/ Bi, Ac, and Bi-have been produced and evaluated (pre)clinically for therapeutic purposes. In this short review article, the most important routes of production of these radiometals are critically discussed, as are examples of their application in preclinical and clinical studies.
[Mh] Termos MeSH primário: Partículas alfa/uso terapêutico
Partículas beta/uso terapêutico
Elétrons
Metais/química
Radioquímica/métodos
Radioisótopos/química
Radioisótopos/uso terapêutico
[Mh] Termos MeSH secundário: Animais
Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Metals); 0 (Radioisotopes)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170925
[Lr] Data última revisão:
170925
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170903
[St] Status:MEDLINE
[do] DOI:10.2967/jnumed.116.186825


  6 / 2424 MEDLINE  
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[PMID]:28820355
[Au] Autor:Sollazzo A; Brzozowska B; Cheng L; Lundholm L; Haghdoost S; Scherthan H; Wojcik A
[Ad] Endereço:a Centre for Radiation Protection Research, Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden.
[Ti] Título:Alpha Particles and X Rays Interact in Inducing DNA Damage in U2OS Cells.
[So] Source:Radiat Res;188(4):400-411, 2017 Oct.
[Is] ISSN:1938-5404
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Survivors of the atomic bombings of Hiroshima and Nagasaki are monitored for health effects within the Life Span Study (LSS). The LSS results represent the most important source of data about cancer effects from ionizing radiation exposure, which forms the foundation for the radiation protection system. One uncertainty connected to deriving universal risk factors from these results is related to the problem of mixed radiation qualities. The A-bomb explosions generated a mixed beam of the sparsely ionizing gamma radiation and densely ionizing neutrons. However, until now the possible interaction of the two radiation types of inducing biological effects has not been taken into consideration. The existence of such interaction would suggest that the application of risk factors derived from the LSS to predict cancer effects after pure gamma-ray irradiation (such as in the Fukushima prefecture) leads to an overestimation of risk. To analyze the possible interaction of radiation types, a mixed-beam exposure facility was constructed where cells can be exposed to sparsely ionizing X rays and densely ionizing alpha particles. U2OS cells were used, which are stably transfected with a plasmid coding for the DNA repair gene 53BP1 coupled to a gene coding for the green fluorescent protein (GFP). The induction and repair of DNA damage, which are known to be related to cancer induction, were analyzed. The results suggest that alpha particles and X rays interact, leading to cellular and possibly cancer effects, which cannot be accurately predicted based on assuming simple additivity of the individual mixed-beam components.
[Mh] Termos MeSH primário: Partículas alfa/efeitos adversos
Dano ao DNA
[Mh] Termos MeSH secundário: Linhagem Celular Tumoral
Quebras de DNA de Cadeia Dupla/efeitos da radiação
Reparo do DNA/efeitos da radiação
Relação Dose-Resposta à Radiação
Seres Humanos
Cinética
Proteína 1 de Ligação à Proteína Supressora de Tumor p53/metabolismo
Raios X/efeitos adversos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Tumor Suppressor p53-Binding Protein 1)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171017
[Lr] Data última revisão:
171017
[Sb] Subgrupo de revista:IM; S
[Da] Data de entrada para processamento:170819
[St] Status:MEDLINE
[do] DOI:10.1667/RR14803.1


  7 / 2424 MEDLINE  
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[PMID]:28797482
[Au] Autor:Bertolaso P; Leroy L; Gross-Goupil M; Aupee O; Ravaud A; Roubaud G; Cazeau AL; Le Moulec S
[Ad] Endereço:CHU Saint-André, 1, rue Jean-Burguet, 33075 Bordeaux cedex, France.
[Ti] Título:[Principles, modalities and indications of the administration of Radium in cancers, focus on metastatic prostate cancer: State of arts].
[Ti] Título:Principes, modalités et indication de l'administration du Radium dans les cancers, focus sur le cancer de la prostate métastatique : état des lieux..
[So] Source:Bull Cancer;104(9):762-770, 2017 Sep.
[Is] ISSN:1769-6917
[Cp] País de publicação:France
[La] Idioma:fre
[Ab] Resumo:Prostate cancer is the first cancer in men and has a specific tropism to bones. This tropism provided the rationale to develop bone targeting radiopharmaceutical agents, such as strontium, samarium and more recently the Radium-223, an alpha-emitter. In a phase III trial, ALSYMPCA, Radium-223 not only improved pain relief, but also impacted on overall survival. Despite an approval by both FDA and EMA, prescription of this agent remains limited by the lack of refund, especially in France. Radium-223 is currently evaluated in several clinical trials (combination with chemotherapy, radiotherapy or hormone therapy) in order to optimize the therapeutic sequences in metastatic bone prostate cancer and argues for being incorporated into the current therapeutic arsenal.
[Mh] Termos MeSH primário: Neoplasias Ósseas/radioterapia
Neoplasias Ósseas/secundário
Dor do Câncer/radioterapia
Neoplasias da Próstata
Compostos Radiofarmacêuticos/uso terapêutico
Rádio (Elemento)/uso terapêutico
[Mh] Termos MeSH secundário: Partículas alfa/uso terapêutico
Partículas beta/uso terapêutico
Neoplasias Ósseas/mortalidade
Dor do Câncer/etiologia
Ensaios Clínicos como Assunto
Raios gama/uso terapêutico
Seres Humanos
Masculino
Proteção Radiológica
Compostos Radiofarmacêuticos/efeitos adversos
Rádio (Elemento)/efeitos adversos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Radiopharmaceuticals); W90AYD6R3Q (Radium)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170921
[Lr] Data última revisão:
170921
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170812
[St] Status:MEDLINE


  8 / 2424 MEDLINE  
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[PMID]:28658304
[Au] Autor:Kodaira S; Li HK; Konishi T; Kitamura H; Kurano M; Hasegawa S
[Ad] Endereço:Radiation Measurement Research Team, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.
[Ti] Título:Validating α-particle emission from 211At-labeled antibodies in single cells for cancer radioimmunotherapy using CR-39 plastic nuclear track detectors.
[So] Source:PLoS One;12(6):e0178472, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Recently, 211At has received increasing attention as a potential radionuclide for cancer radioimmunotherapy. It is a α-particle emitter, which is extremely effective against malignant cells. We demonstrate a method to verify the efficiency of 211At-labeled trastuzumab antibodies (211At-trastuzumab) against HER2 antigens, which has not been determined for radioimmunotherapy. A CR-39 plastic nuclear detector is used for measuring the position and the linear energy transfer (LET) of individual 211At α- particle tracks. The tracks and 211At-trastuzumab-binding cells were co-visualized by using the geometric information recorded on the CR-39. HER2-positive human gastric cancer cells (NCI-N87), labelled with 211At-trastuzumab, were dropped on the centre of the CR-39 plate. Microscope images of the cells and the corresponding α-tracks acquired by position matching were obtained. In addition, 3.5 cm × 3.5 cm macroscopic images of the whole plate were acquired. The distribution of number of α-particles emitted from single cells suggests that 80% of the 211At-trastuzumab-binding cells emitted α-particles. It also indicates that the α-particles may strike the cells several times along their path. The track-averaged LET of the α-particles is evaluated to be 131 keV/µm. These results will enable quantitative evaluation of delivered doses to target cells, and will be useful for the in vitro assessment of 211At-based radioimmunotherapeutic agents.
[Mh] Termos MeSH primário: Partículas alfa/uso terapêutico
Anticorpos Monoclonais/uso terapêutico
Astato/química
Plásticos/química
Polietilenoglicóis/química
Radioimunoterapia/métodos
[Mh] Termos MeSH secundário: Linhagem Celular Tumoral
Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE; VALIDATION STUDIES
[Nm] Nome de substância:
0 (Antibodies, Monoclonal); 0 (Plastics); 25656-90-0 (CR 39); 30IQX730WE (Polyethylene Glycols); XI595HAL7H (Astatine)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170928
[Lr] Data última revisão:
170928
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170629
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0178472


  9 / 2424 MEDLINE  
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[PMID]:28609210
[Au] Autor:Kaminska M; Fersten E; Koziara H; Królicki B
[Ad] Endereço:a Institute of Applied Psychology - Centre of Adult Clinical Psychology, The Maria Grzegorzewska University , Warsaw , Poland.
[Ti] Título:Quality of life in patients with brain tumors in the course of alpha therapy.
[So] Source:J Psychosoc Oncol;35(5):631-644, 2017 Sep-Oct.
[Is] ISSN:1540-7586
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The aim of the study was to assess subjective quality of life in patients receiving alpha therapy for malignant tumors (glioblastoma multiforme, GBM) of the brain. No significant differences in self-assessed quality of life were found between GBM patients in the course of α-therapy and healthy controls, the two groups differed only as regards somatic symptoms. Moreover, the stronger the respondents' sense of self-efficacy, the higher their subjective quality of life. The findings may have practical implications for clinical psychology, namely, it seems worthwhile to build up the patient's sense of control of his own health.
[Mh] Termos MeSH primário: Partículas alfa/uso terapêutico
Neoplasias Encefálicas/radioterapia
Glioblastoma/radioterapia
Qualidade de Vida/psicologia
Radioisótopos/uso terapêutico
[Mh] Termos MeSH secundário: Adulto
Idoso
Atitude Frente à Saúde
Neoplasias Encefálicas/psicologia
Estudos de Casos e Controles
Feminino
Glioblastoma/psicologia
Seres Humanos
Masculino
Meia-Idade
Autoeficácia
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Radioisotopes)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171030
[Lr] Data última revisão:
171030
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170614
[St] Status:MEDLINE
[do] DOI:10.1080/07347332.2017.1340390


  10 / 2424 MEDLINE  
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[PMID]:28565963
[Au] Autor:de Toledo SM; Buonanno M; Harris AL; Azzam EI
[Ad] Endereço:a Department of Radiology , RUTGERS New Jersey Medical School Cancer Center , Newark , NJ , USA.
[Ti] Título:Genomic instability induced in distant progeny of bystander cells depends on the connexins expressed in the irradiated cells.
[So] Source:Int J Radiat Biol;93(10):1182-1194, 2017 Oct.
[Is] ISSN:1362-3095
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:PURPOSE: To examine the time window during which intercellular signaling though gap junctions mediates non-targeted (bystander) effects induced by moderate doses of ionizing radiation; and to investigate the impact of gap junction communication on genomic instability in distant progeny of bystander cells. MATERIALS AND METHODS: A layered cell culture system was developed to investigate the propagation of harmful effects from irradiated normal or tumor cells that express specific connexins to contiguous bystander normal human fibroblasts. Irradiated cells were exposed to moderate mean absorbed doses from 3.7 MeV α particle, 1000 MeV/u iron ions, 600 MeV/u silicon ions, or Cs γ rays. Following 5 h of co-culture, pure populations of bystander cells, unexposed to secondary radiation, were isolated and DNA damage and oxidative stress was assessed in them and in their distant progeny (20-25 population doublings). RESULTS: Increased frequency of micronucleus formation and enhanced oxidative changes were observed in bystander cells co-cultured with confluent cells exposed to either sparsely ionizing ( Cs γ rays) or densely ionizing (α particles, energetic iron or silicon ions) radiations. The irradiated cells propagated signals leading to biological changes in bystander cells within 1 h of irradiation, and the effect required cellular coupling by gap junctions. Notably, the distant progeny of isolated bystander cells also exhibited increased levels of spontaneous micronuclei. This effect was dependent on the type of junctional channels that coupled the irradiated donor cells with the bystander cells. Previous work showed that gap junctions composed of connexin26 (Cx26) or connexin43 (Cx43) mediate toxic bystander effects within 5 h of co-culture, whereas gap junctions composed of connexin32 (Cx32) mediate protective effects. In contrast, the long-term progeny of bystander cells expressing Cx26 or Cx43 did not display elevated DNA damage, whereas those coupled by Cx32 had enhanced DNA damage. CONCLUSIONS: In response to moderate doses from either sparsely or densely ionizing radiations, toxic and protective effects are rapidly communicated to bystander cells through gap junctions. We infer that bystander cells damaged by the initial co-culture (expressing Cx26 or Cx43) die or undergo proliferative arrest, but that the bystander cells that were initially protected (expressing Cx32) express DNA damage upon sequential passaging. Together, the results inform the roles that intercellular communication play under stress conditions, and aid assessment of the health risks of exposure to ionizing radiation. Identification of the communicated molecules may enhance the efficacy of radiotherapy and help attenuate its debilitating side-effects.
[Mh] Termos MeSH primário: Efeito Espectador/efeitos da radiação
Conexinas/metabolismo
Regulação da Expressão Gênica/efeitos da radiação
Instabilidade Genômica/efeitos da radiação
[Mh] Termos MeSH secundário: Partículas alfa/efeitos adversos
Dano ao DNA
Relação Dose-Resposta à Radiação
Fibroblastos/citologia
Fibroblastos/efeitos da radiação
Junções Comunicantes/metabolismo
Junções Comunicantes/efeitos da radiação
Seres Humanos
Espaço Intracelular/metabolismo
Espaço Intracelular/efeitos da radiação
Oxirredução/efeitos da radiação
Permeabilidade/efeitos da radiação
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Connexins)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171010
[Lr] Data última revisão:
171010
[Sb] Subgrupo de revista:IM; S
[Da] Data de entrada para processamento:170602
[St] Status:MEDLINE
[do] DOI:10.1080/09553002.2017.1334980



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