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[PMID]:28115407
[Au] Autor:De Jonge C
[Ad] Endereço:Andrology Program, University of Minnesota Medical Center, 606 24th Avenue South, Suite 525, Minneapolis, MN 55454, USA.
[Ti] Título:Biological basis for human capacitation-revisited.
[So] Source:Hum Reprod Update;23(3):289-299, 2017 May 01.
[Is] ISSN:1460-2369
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: A little more than a decade ago a review entitled 'Biological basis for human capacitation' was published. A primary conclusion of the review was that with all the technological advances that have been made since the first experiments demonstrated the in vivo requirement of capacitation for fertilization, very little progress had since been made, most significantly for human. OBJECTIVE AND RATIONALE: The present review was carried out to provide an update on the biological basis for human capacitation. It briefly revisits the original schema, presents a review of the literature that urged research interest in human sperm capacitation and puts under the spotlight the original definition of capacitation balanced against the limitations of experiments in vitro to characterize a complex process that necessarily mandates a female component, and very recent findings in the mouse. It also includes proposed considerations for new thinking regarding capacitation, and progress toward understanding the biology of human capacitation. SEARCH METHODS: The PubMed, Google Scholar and Scopus literature databases were reviewed extensively using inclusive, broad and multispecies search terms without publication date limitation. OUTCOMES: Comprehensive screening of the literature database showed that no papers regarding human sperm capacitation in vivo have been published in the past 20 years. Recent experiments in the mouse have provided compelling and unanticipated data regarding capacitation and in vivo fertilization. Questions were posed and addressed regarding: stimuli for initiation of capacitation, capacitation relative to the cumulus-oocyte complex, comparison between in vivo and in vitro capacitation, and potential species-specific differences in location and timing of capacitation. WIDER IMPLICATIONS: There has been no progress on the in vivo biology of human sperm capacitation since before the turn of the century. Human IVF and its technologies may likely have inhibited, and continue to hold back, any future in vivo experiments that would address one or more questions regarding acquisition of fertilizing capacity in human. The limiting factor for progress in the area is access to funding and human subjects.
[Mh] Termos MeSH primário: Capacitação Espermática/fisiologia
Espermatozoides/fisiologia
[Mh] Termos MeSH secundário: Animais
Pesquisa Biomédica
Feminino
Seres Humanos
Masculino
Camundongos
Editoração/estatística & dados numéricos
Coelhos
Transporte Espermático/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171002
[Lr] Data última revisão:
171002
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170125
[St] Status:MEDLINE
[do] DOI:10.1093/humupd/dmw048


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[PMID]:27807895
[Au] Autor:Rowlison T; Ottinger MA; Comizzoli P
[Ad] Endereço:Smithsonian Conservation Biology Institute, Washington, DC, USA.
[Ti] Título:Deciphering the mechanisms involving cenexin, ninein and centriolin in sperm maturation during epididymal transit in the domestic cat.
[So] Source:Reprod Domest Anim;52 Suppl 2:193-196, 2017 Apr.
[Is] ISSN:1439-0531
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:The sperm centrosome is an essential organelle with a key role in organizing the sperm aster for proper syngamy and formation of the first mitotic spindle. The sperm cell acquires the functional capability during epididymal transit by incorporation of key factors. The objective of the study was to identify these key maturation proteins, such as ninein and centriolin as well as cenexin-a scaffold protein that serves to bind ninein and centriolin. Epididymal samples were dissected from 17 adult cat testes (>1 year old) and spermatozoa were extracted from the different regions, including rete testis, caput, corpus, cauda and vas deferens. Tissue samples and sperm cells were fixed separately in 4% paraformaldehyde before immunostaining with anticenexin, ninein or centriolin antibodies. Results showed that the proportion of sperm cells with cenexin localized at the centrosome progressively increased along the tract with the lowest percentage of stained cells in the testis (mean = 45%) and highest in the cauda (mean = 81%). Although not significant, the intensity of cenexin immunofluorescence in positive cells increased twofold from the testis to vas deferens. There was no significant difference in the proportion of sperm labelled with centriolin or ninein (ranges of 21%-26% and 33%-48% between segments, respectively) or the intensity (±58% and ±63% change as compared to testis, respectively). Cenexin may serve as a scaffold protein for centriolin and ninein, as the vast majority of spermatozoa only displayed colocalization of these proteins when cenexin was also present (mean = 85% and 91% colocalization, respectively). In summary, these results could be applied to future efforts to create an in vitro culture system capable of rescuing the impaired centrosome of an infertile male, with particular potential for wild felid conservation.
[Mh] Termos MeSH primário: Gatos
Proteínas de Ciclo Celular/fisiologia
Proteínas do Citoesqueleto/fisiologia
Proteínas de Choque Térmico/fisiologia
Maturação do Esperma/fisiologia
Transporte Espermático/fisiologia
[Mh] Termos MeSH secundário: Animais
Epididimo/citologia
Masculino
Espermatozoides/fisiologia
Testículo/citologia
Ducto Deferente/citologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Cell Cycle Proteins); 0 (Cytoskeletal Proteins); 0 (Heat-Shock Proteins)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170906
[Lr] Data última revisão:
170906
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161104
[St] Status:MEDLINE
[do] DOI:10.1111/rda.12831


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[PMID]:27624988
[Au] Autor:García-Vázquez FA; Gadea J; Matás C; Holt WV
[Ad] Endereço:Department of Physiology, Faculty of Veterinary Science, International Excellence Campus for Higher Education and Research "Campus Mare Nostrum", University of Murcia, Murcia 30100, Spain.
[Ti] Título:Importance of sperm morphology during sperm transport and fertilization in mammals.
[So] Source:Asian J Androl;18(6):844-850, 2016 Nov-Dec.
[Is] ISSN:1745-7262
[Cp] País de publicação:China
[La] Idioma:eng
[Ab] Resumo:After natural or artificial insemination, the spermatozoon starts a journey from the site of deposition to the place of fertilization. However, only a small subset of the spermatozoa deposited achieves their goal: to reach and fertilize the egg. Factors involved in controlling sperm transport and fertilization include the female reproductive tract environment, cell-cell interactions, gene expression, and phenotypic sperm traits. Some of the significant determinants of fertilization are known (i.e., motility or DNA status), but many sperm traits are still indecipherable. One example is the influence of sperm dimensions and shape upon transport within the female genital tract towards the oocyte. Biophysical associations between sperm size and motility may influence the progression of spermatozoa through the female reproductive tract, but uncertainties remain concerning how sperm morphology influences the fertilization process, and whether only the sperm dimensions per se are involved. Moreover, such explanations do not allow the possibility that the female tract is capable of distinguishing fertile spermatozoa on the basis of their morphology, as seems to be the case with biochemical, molecular, and genetic properties. This review focuses on the influence of sperm size and shape in evolution and their putative role in sperm transport and selection within the uterus and the ability to fertilize the oocyte.
[Mh] Termos MeSH primário: Fertilização/fisiologia
Transporte Espermático/fisiologia
Interações Espermatozoide-Óvulo/fisiologia
Espermatozoides/citologia
[Mh] Termos MeSH secundário: Animais
Forma Celular/fisiologia
Feminino
Seres Humanos
Masculino
Mamíferos
Motilidade Espermática/fisiologia
Cauda do Espermatozoide/fisiologia
Espermatozoides/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160915
[St] Status:MEDLINE
[do] DOI:10.4103/1008-682X.186880


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[PMID]:27222348
[Au] Autor:Gautier C; Barrier-Battut I; Guénon I; Goux D; Delalande C; Bouraïma-Lelong H
[Ad] Endereço:Normandie Univ, France; UNICAEN, EA2608, OeReCa, F-14032 Caen, France; USC-INRA 1377, F-14032 Caen, France.
[Ti] Título:Implication of the estrogen receptors GPER, ESR1, ESR2 in post-testicular maturations of equine spermatozoa.
[So] Source:Gen Comp Endocrinol;233:100-108, 2016 Jul 01.
[Is] ISSN:1095-6840
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Estrogen receptors ESR1, ESR2 and GPER are present on mature ejaculated horse spermatozoa, suggesting these cells as putative targets for estrogens. Indeed, spermatozoa are exposed to high level of estrogens during the transit in the male and female genital tracts but their roles are not investigated. So, we evaluated in vitro the role of 17ß-estradiol during post-testicular maturations: regulation of motility, capacitation and acrosome reaction. Moreover according to the pseudo-seasonal breeder status of the stallion, we analyzed the putative seasonal variations in the presence of ESRs in spermatozoa. We showed that ESRs are more present on stallion sperm during the breeding season. We showed that capacitation and acrosome reaction are independent of estradiol action in horse. Estradiol can weakly modulate the motility and this effect is strictly associated with GPER and not with ESR1 and ESR2. The subcellular localization of GPER in the neck on stallion sperm is coherent with this effect. It seems that estrogens are not major regulators of sperm maturations associated to mare genital tract, so they could act during the epididymal maturations.
[Mh] Termos MeSH primário: Receptor alfa de Estrogênio/fisiologia
Receptor beta de Estrogênio/fisiologia
Cavalos/fisiologia
Receptores Acoplados a Proteínas-G/fisiologia
Capacitação Espermática
Maturação do Esperma
[Mh] Termos MeSH secundário: Reação Acrossômica/efeitos dos fármacos
Animais
Epididimo/efeitos dos fármacos
Epididimo/metabolismo
Estradiol/farmacologia
Receptor alfa de Estrogênio/metabolismo
Receptor beta de Estrogênio/metabolismo
Feminino
Cavalos/genética
Masculino
Receptores Estrogênicos/metabolismo
Receptores Estrogênicos/fisiologia
Receptores Acoplados a Proteínas-G/metabolismo
Capacitação Espermática/efeitos dos fármacos
Maturação do Esperma/efeitos dos fármacos
Maturação do Esperma/fisiologia
Motilidade Espermática/efeitos dos fármacos
Transporte Espermático/efeitos dos fármacos
Espermatozoides/efeitos dos fármacos
Espermatozoides/metabolismo
Espermatozoides/fisiologia
Distribuição Tecidual
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Estrogen Receptor alpha); 0 (Estrogen Receptor beta); 0 (Receptors, Estrogen); 0 (Receptors, G-Protein-Coupled); 4TI98Z838E (Estradiol)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:171027
[Lr] Data última revisão:
171027
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160526
[St] Status:MEDLINE


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[PMID]:26963046
[Au] Autor:Dacheux JL; Dacheux F; Druart X
[Ad] Endereço:INRA, CNRS, Université de Tours, Haras Nationaux, SPARC (Station de Physiologie de la Reproduction et des Comportements), 37380, Nouzilly, France. Electronic address: jean-louis.dacheux@orange.fr.
[Ti] Título:Epididymal protein markers and fertility.
[So] Source:Anim Reprod Sci;169:76-87, 2016 Jun.
[Is] ISSN:1873-2232
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:The last stages of male gamete differentiation occur outside the gonad in a specific environment controlled by the epididymal epithelium. All the fundamental characteristics of a fertile spermatozoon are acquired sequentially during transit through the epididymal tubule. Full understanding of the mechanisms involved in these gamete modifications is a key to understanding and controlling such important stages in male fertility. With the development of new large scale technologies, large amounts of information give hope of identifying the fundamental elements involved in such cellular events and of being able to obtain some markers predictive of male fertility that would be valuable both in human and/or animal reproduction.
[Mh] Termos MeSH primário: Epididimo/metabolismo
Regulação da Expressão Gênica/fisiologia
Espermatogênese/fisiologia
Espermatozoides/fisiologia
[Mh] Termos MeSH secundário: Animais
Biomarcadores
Diferenciação Celular/fisiologia
Masculino
Especificidade da Espécie
Maturação do Esperma/fisiologia
Motilidade Espermática/fisiologia
Transporte Espermático/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Biomarkers)
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170119
[Lr] Data última revisão:
170119
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160311
[St] Status:MEDLINE


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[PMID]:26382022
[Au] Autor:Kölle S
[Ad] Endereço:Health Sciences Centre, UCD School of Medicine & Medical Science, University College Dublin, Belfield, Dublin 4, Ireland.
[Ti] Título:Transport, Distribution and Elimination of Mammalian Sperm Following Natural Mating and Insemination.
[So] Source:Reprod Domest Anim;50 Suppl 3:2-6, 2015 Sep.
[Is] ISSN:1439-0531
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:The integrity of transport, distribution and elimination of sperm in the female genital tract plays a pivotal role for successful reproduction in mammals. At coitus, millions or billions of sperm are deposited either into the anterior vagina (human, primates), the cervix (most mammalian species) or the uterus (pig). In most species, the first anatomical barrier is the cervix, where spermatozoa with poor morphology and motility are filtered out by sticking to the cervical mucus. The second anatomical barrier is the uterotubal junction (UTJ) with its tortuous and narrow lumen. Finally, only a few thousand sperm enter the oviduct and less than 100 sperm reach the site of fertilization. As soon as the sperm enter the oviduct, they form a sperm reservoir enabling them to stay vital and maintain fertilizing capacity for 3-4 days (cow, horse) up to several months (bats). After ovulation, mammalian sperm show hyperactivation which allows them to detach from the tubal epithelium and migrate to the site of fertilization. This review will focus on recent insights of sperm transport, sperm storage and sperm-oviduct interaction in mammals which have been gained by live cell imaging in cows and mice under near in vivo conditions. Detailed knowledge of the biology of spermatozoa within the female genital tract creates the basis for new therapeutic concepts for male subfertility and infertility - an essential prerequisite to increase success rates in assisted reproduction.
[Mh] Termos MeSH primário: Cruzamento
Inseminação
Mamíferos
Transporte Espermático/fisiologia
Espermatozoides/fisiologia
[Mh] Termos MeSH secundário: Animais
Bovinos
Muco do Colo Uterino
Colo do Útero
Copulação
Tubas Uterinas
Feminino
Fertilização
Masculino
Camundongos
Ovulação/fisiologia
Interações Espermatozoide-Óvulo
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1606
[Cu] Atualização por classe:150919
[Lr] Data última revisão:
150919
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150919
[St] Status:MEDLINE
[do] DOI:10.1111/rda.12576


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[PMID]:26119829
[Au] Autor:García-Vázquez FA; Hernández-Caravaca I; Matás C; Soriano-Úbeda C; Abril-Sánchez S; Izquierdo-Rico MJ
[Ad] Endereço:Department of Physiology, Faculty of Veterinary Science, International Excellence Campus for Higher Education and Research "Campus Mare Nostrum", University of Murcia, Murcia 30100, Spain.
[Ti] Título:Morphological study of boar sperm during their passage through the female genital tract.
[So] Source:J Reprod Dev;61(5):407-13, 2015.
[Is] ISSN:1348-4400
[Cp] País de publicação:Japan
[La] Idioma:eng
[Ab] Resumo:Once deposited in the female tract, sperm face a series of challenges that must be overcome to ensure the presence of an adequate normal sperm population close to the site of fertilization. Our aim was to evaluate the influence of the uterine milieu on boar sperm morphology. In experiment 1, sperm morphology was evaluated in the backflow (60 min after insemination) and within the uterotubal junction (UTJ) (collected ~24 h after insemination) following intrauterine sperm deposition (n = 6) and compared with the morphology of the sperm in the insemination dose. In experiment 2, the influence of the uterine fluid (UF) on sperm morphological modifications was evaluated. For this purpose, ejaculated (n = 4) and epididymal (n = 4) sperm were in vitro incubated with or without UF for 2 and 24 h. In both experiments, sperm were classified as normal, having a cytoplasmic droplet (proximal or distal) or having tail defects. The results of experiment 1 pointed to an increase in morphologically abnormal sperm collected in the backflow (27.70%) and a reduction of the same in the UTJ (2.12%) compared with the insemination dose (17.75%) (P < 0.05). In experiment 2, incubation of ejaculated sperm with UF did not provoke any morphological modifications; however, when epididymal sperm were incubated with UF, a pronounced increase in the percentage of normal sperm was evident after 24 h compared with the initial dose (from 25.77% to 53.58%, P < 0.05), mainly due to distal cytoplasmatic droplet shedding (53.22 vs. 20.20%). In conclusion, almost all the sperm that colonize the UTJ had a normal morphology, with part of the abnormal sperm having been discarded in the backflow and part selected/modified on their way to the oviduct. UF seems to influence cytoplasmic distal droplet removal, as demonstrated previously in seminal plasma.
[Mh] Termos MeSH primário: Secreções Corporais/fisiologia
Tubas Uterinas/fisiologia
Transporte Espermático
Espermatozoides/citologia
Sus scrofa/fisiologia
Útero/fisiologia
[Mh] Termos MeSH secundário: Matadouros
Animais
Animais Endogâmicos
Secreções Corporais/secreção
Forma Celular
Senescência Celular
Cruzamentos Genéticos
Estruturas Citoplasmáticas
Ejaculação
Epididimo/citologia
Tubas Uterinas/secreção
Feminino
Inseminação Artificial/veterinária
Masculino
Análise do Sêmen/veterinária
Espanha
Espermatozoides/fisiologia
Útero/secreção
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1608
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150630
[St] Status:MEDLINE
[do] DOI:10.1262/jrd.2014-170


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[PMID]:25645087
[Au] Autor:Cavariani MM; de Almeida Kiguti LR; de Lima Rosa J; de Araújo Leite GA; Silva PV; Pupo AS; De Grava Kempinas W
[Ad] Endereço:Department of Morphology, Institute of Biosciences, UNESP - Univ. Estadual Paulista, Botucatu, São Paulo, Brazil.
[Ti] Título:Bupropion treatment increases epididymal contractility and impairs sperm quality with no effects on the epididymal sperm transit time of male rats.
[So] Source:J Appl Toxicol;35(9):1007-16, 2015 Sep.
[Is] ISSN:1099-1263
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Bupropion is a dopamine (DA) and norepinephrine (NE) reuptake inhibitor used as smoking cessation and antidepressant drug with a lower incidence of male sexual dysfunction. We showed previously that sibutramine, a norepinephrine/serotonine reuptake inhibitor, reduced male rat fertility. As there are no studies evaluating the impact of bupropion treatment on spermatic parameters and male fertility, we evaluated the effects of bupropion treatment (15 and 30 mg kg(-1), 30 days) on sexual behavior, spermatic parameters and fertility of male Wistar rats and on the epididymal duct in vitro contractility. Bupropion 15 mg kg(-1) increased the serum luteinizing hormone level and the epididymal duct contractility, but the sperm quality was not affected. At 30 mg kg(-1) bupropion impaired sperm quality increasing the incidence of non-progressive sperm. The male sexual behavior and fertility were not modified at both bupropion doses. These results, in rats, suggest the importance of studies evaluating the effects of bupropion on the human male sperm quality.
[Mh] Termos MeSH primário: Bupropiona/toxicidade
Inibidores da Captação de Dopamina/toxicidade
Epididimo/efeitos dos fármacos
Contração Muscular/efeitos dos fármacos
Transporte Espermático/efeitos dos fármacos
Espermatozoides/efeitos dos fármacos
[Mh] Termos MeSH secundário: Animais
Epididimo/fisiopatologia
Feminino
Fertilidade/efeitos dos fármacos
Hormônio Luteinizante/sangue
Masculino
Tamanho do Órgão/efeitos dos fármacos
Ratos Wistar
Comportamento Sexual Animal/efeitos dos fármacos
Contagem de Espermatozoides
Motilidade Espermática/efeitos dos fármacos
Espermatozoides/patologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Dopamine Uptake Inhibitors); 01ZG3TPX31 (Bupropion); 9002-67-9 (Luteinizing Hormone)
[Em] Mês de entrada:1605
[Cu] Atualização por classe:150727
[Lr] Data última revisão:
150727
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150204
[St] Status:MEDLINE
[do] DOI:10.1002/jat.3089


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[PMID]:25153439
[Au] Autor:Lejeune H; Lapoirie M; Brosse A; Cuzin B; Giscard d'Estaing S; Plotton I
[Ad] Endereço:Inserm U846, service de médecine de la reproduction, laboratoire de biologie de la reproduction, université Claude-Bernard Lyon 1, hôpital Femme-Mère-Enfant, CHU de Lyon, hospices civils de Lyon, 59, boulevard Pinel, 69500 Bron, France. Electronic address: herve.lejeune@chu-lyon.fr.
[Ti] Título:[Medical optimisation of sperm retrieval in non obstructive azoospermia].
[Ti] Título:Optimisation médicale du recueil de spermatozoïdes dans les azoospermies non obstructives..
[So] Source:Gynecol Obstet Fertil;42(9):640-3, 2014 Sep.
[Is] ISSN:1769-6682
[Cp] País de publicação:France
[La] Idioma:fre
[Ab] Resumo:Medical optimisation of sperm retrieval in non-obstructive azoospermia is reviewed. Gonadotropin treatment of hypogonadotropic hypogonadism allows obtaining sperms in the ejaculate in about 90% of cases provided the duration of treatment was long enough. TESE is indicated in case of persistent azoospermia at 2 years of continuous treatment. Some publications reported a possible effect of hormonal treatments (FSH, hCG, anti-estrogens, aromatase inhibitors) in primary spermatogenic failure, but mainly in cases selected for their favourable histology and normal hormonal levels. The effect on unselected cases remains doubtful. Conversely, the effect of the treatment of varicoceles is significant. Other medical treatments or advises need further investigations.
[Mh] Termos MeSH primário: Azoospermia/complicações
Infertilidade Masculina/terapia
Recuperação Espermática
[Mh] Termos MeSH secundário: Azoospermia/tratamento farmacológico
Hormônio Foliculoestimulante/administração & dosagem
Seres Humanos
Hipogonadismo/complicações
Hipogonadismo/tratamento farmacológico
Infertilidade Masculina/etiologia
Masculino
Injeções de Esperma Intracitoplásmicas
Transporte Espermático
Espermatogênese
Testículo/citologia
[Pt] Tipo de publicação:ENGLISH ABSTRACT; JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
9002-68-0 (Follicle Stimulating Hormone)
[Em] Mês de entrada:1504
[Cu] Atualização por classe:140901
[Lr] Data última revisão:
140901
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140826
[St] Status:MEDLINE


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[PMID]:24895185
[Au] Autor:Lipke E; Ramírez MJ; Michalik P
[Ad] Endereço:Zoological Institute and Museum, Ernst-Moritz-Arndt University of Greifswald, J.-S.-Bach-Straße 11/12, Greifswald, D-17489, Germany.
[Ti] Título:Ultrastructure of spermatozoa of Orsolobidae (Haplogynae, Araneae) with implications on the evolution of sperm transfer forms in Dysderoidea.
[So] Source:J Morphol;275(11):1238-57, 2014 Nov.
[Is] ISSN:1097-4687
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Haplogynae are highly diverse with respect to the primary male genital system and sperm characteristics. Additionally, all sperm transfer forms (STF) known for spiders are present. Besides individually transferred sperm (cleistospermia), sperm are transferred as conjugates, both primary (synspermia) and secondary sperm conjugates (coenospermia, rouleaux) occur. Nevertheless, the ultrastructure of spermatozoa and STF are described for few Haplogynae and often only one representative species was studied, resulting in a superficial insight in the evolution of these traits. To elucidate the evolution of STF within Haplogynae we investigated representatives of four genera of the dysderoid family Orsolobidae. Our data show the presence of synspermia (Orsolobus, Osornolobus, Hickmanolobus, and Tasmanoonops) and also cleistospermia (Osornolobus). The occurrence of different STF within one family or even genus has not been described for any other spider taxon so far. Moreover, the synspermia of species of Tasmanoonops and Hickmanolobus were not covered by a secretion sheath suggesting a previously unknown strategy of transferring sperm that is possibly related to sperm residency time or female triggered processes after copulation. Based on serial ultrathin sectioning and subsequent 3D-reconstruction, we obtained detailed measurements revealing remarkable size differences of STF. To evaluate the previously suggested correlation with the most distal region of the spermophor inside the embolus (intromittent part of the copulatory organ) we measured the diameter of the spermophor using micro-computed X-ray tomography data to obtain corresponding morphometric parameters. Based on these data only two species show similarity in STF and spermophor diameter.
[Mh] Termos MeSH primário: Genitália Masculina/anatomia & histologia
Espermatozoides/ultraestrutura
Aranhas/anatomia & histologia
[Mh] Termos MeSH secundário: Animais
Evolução Biológica
Núcleo Celular/ultraestrutura
Copulação
Genitália Masculina/diagnóstico por imagem
Genitália Masculina/ultraestrutura
Imagem Tridimensional
Corpos de Inclusão/ultraestrutura
Masculino
Especificidade da Espécie
Transporte Espermático
Espermatogênese
Aranhas/classificação
Aranhas/fisiologia
Tomografia Computadorizada por Raios X
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1412
[Cu] Atualização por classe:161125
[Lr] Data última revisão:
161125
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140605
[St] Status:MEDLINE
[do] DOI:10.1002/jmor.20298



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