Base de dados : MEDLINE
Pesquisa : G05.342 [Categoria DeCS]
Referências encontradas : 796 [refinar]
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[PMID]:29369562
[Au] Autor:Sulimova GE; Voronkova VN; Perchun AV; Gorlov IF; Randelin AV; Slozhenkina MI; Zlobina EY
[Ti] Título:[Characterization of the Russian beef cattle breed gene pools using inter simple sequence repeat DNA analysis (ISSR analysis)].
[So] Source:Genetika;52(9):1081-8, 2016 Sep.
[Is] ISSN:0016-6758
[Cp] País de publicação:Russia (Federation)
[La] Idioma:rus
[Ab] Resumo:The gene pools of beef cattle breeds bred in Russia were characterized on the basis of inter simple sequence repeat DNA analysis (ISSR analysis). Samples of Aberdeen Angus, Kalmyk, and Kazakh Whitehead breeds from Russia, as well as of Hereford breed, hybrids of Kazakh Whitehead and Hereford breeds, and Kazakh Whitehead breed from the Republic of Kazakhstan, were examined. In the examined breeds, 27 AG-ISSR fragments were identified, 25 of which were polymorphic. The examined breeds were different both in the fragment profiles (the presence/absence of individual ISSR fragments) and in their frequencies. It was demonstrated that the hybrid animals lacked some ISSR fragments that were present with high frequencies in parental forms, suggesting considerable genome rearrangement in the hybrid animals (at the regions of microsatellite localization) in crossings of the individuals from different breeds. The level of genetic diversity in Russian beef breeds was consistent with the values typical of farmed populations (breeds). The genetic diversity parameters assessed by applying Nei's gene diversity index and the Shannon index varied from 0.0218 to 0.0605 and from 0.0225 to 0.0819, respectively. The highest Shannon index value was detected in the Kalmyk breed (0.0837) and Kazakh Whitehead breed from Russia (0.0819), and the highest level of Nei's gene diversity index was found in the Kalmyk breed (0.0562) and in both populations of the Kazakh Whitehead breed (0.0509 and 0.0605). The high level of genetic similarity (according to Nei) was revealed between Russian beef cattle breeds and Hereford cattle: 0.839 (for the Kazakh Whitehead breed from Russia) and 0.769 (for the Kalmyk breed).
[Mh] Termos MeSH primário: Bovinos/genética
Pool Gênico
Variação Genética
Sequências Repetitivas de Ácido Nucleico
[Mh] Termos MeSH secundário: Animais
Federação Russa
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180205
[Lr] Data última revisão:
180205
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180126
[St] Status:MEDLINE


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[PMID]:29190287
[Au] Autor:Hu B; Zeng LP; Yang XL; Ge XY; Zhang W; Li B; Xie JZ; Shen XR; Zhang YZ; Wang N; Luo DS; Zheng XS; Wang MN; Daszak P; Wang LF; Cui J; Shi ZL
[Ad] Endereço:CAS Key Laboratory of Special Pathogens and Biosafety, Center for Emerging Infectious Diseases of Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.
[Ti] Título:Discovery of a rich gene pool of bat SARS-related coronaviruses provides new insights into the origin of SARS coronavirus.
[So] Source:PLoS Pathog;13(11):e1006698, 2017 Nov.
[Is] ISSN:1553-7374
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:A large number of SARS-related coronaviruses (SARSr-CoV) have been detected in horseshoe bats since 2005 in different areas of China. However, these bat SARSr-CoVs show sequence differences from SARS coronavirus (SARS-CoV) in different genes (S, ORF8, ORF3, etc) and are considered unlikely to represent the direct progenitor of SARS-CoV. Herein, we report the findings of our 5-year surveillance of SARSr-CoVs in a cave inhabited by multiple species of horseshoe bats in Yunnan Province, China. The full-length genomes of 11 newly discovered SARSr-CoV strains, together with our previous findings, reveals that the SARSr-CoVs circulating in this single location are highly diverse in the S gene, ORF3 and ORF8. Importantly, strains with high genetic similarity to SARS-CoV in the hypervariable N-terminal domain (NTD) and receptor-binding domain (RBD) of the S1 gene, the ORF3 and ORF8 region, respectively, were all discovered in this cave. In addition, we report the first discovery of bat SARSr-CoVs highly similar to human SARS-CoV in ORF3b and in the split ORF8a and 8b. Moreover, SARSr-CoV strains from this cave were more closely related to SARS-CoV in the non-structural protein genes ORF1a and 1b compared with those detected elsewhere. Recombination analysis shows evidence of frequent recombination events within the S gene and around the ORF8 between these SARSr-CoVs. We hypothesize that the direct progenitor of SARS-CoV may have originated after sequential recombination events between the precursors of these SARSr-CoVs. Cell entry studies demonstrated that three newly identified SARSr-CoVs with different S protein sequences are all able to use human ACE2 as the receptor, further exhibiting the close relationship between strains in this cave and SARS-CoV. This work provides new insights into the origin and evolution of SARS-CoV and highlights the necessity of preparedness for future emergence of SARS-like diseases.
[Mh] Termos MeSH primário: Quirópteros/virologia
Pool Gênico
Genoma Viral/genética
Vírus da SARS/genética
Síndrome Respiratória Aguda Grave/virologia
[Mh] Termos MeSH secundário: Sequência de Aminoácidos/genética
Animais
Infecções por Coronavirus/virologia
Evolução Molecular
Seres Humanos
Recombinação Genética/genética
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171219
[Lr] Data última revisão:
171219
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171201
[St] Status:MEDLINE
[do] DOI:10.1371/journal.ppat.1006698


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[PMID]:28407192
[Au] Autor:Kim SR; Kim KY; Jeong JS; Kim MJ; Kim KH; Choi KH; Kim I
[Ad] Endereço:Department of Agricultural Biology, National Academy of Agricultural Science, Rural Development Administration, Wanju-gun, Republic of Korea.
[Ti] Título:Population genetic characterization of the Japanese oak silkmoth, Antheraea yamamai (Lepidoptera: Saturniidae), using novel microsatellite markers and mitochondrial DNA gene sequences.
[So] Source:Genet Mol Res;16(2), 2017 Apr 13.
[Is] ISSN:1676-5680
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:The Japanese oak silkmoth, Antheraea yamamai Guérin-Méneville, 1861 (Lepidoptera: Saturniidae), is an important natural resource of industrial value for silk fiber production. Owing to a lack of geographic and population genetic information, systematic domestication of An. yamamai has not been possible yet. In this study, 10 microsatellite markers developed using next-generation sequencing and two mitochondrial DNA (mtDNA) gene sequences (COI and ND4) were used to investigate the genetic variation and geographic structure of An. yamamai populations in South Korea. The two mtDNA gene sequences revealed very low total genetic variation and, consequently, low geographic variation, validating the use of more variable molecular markers. Genotyping of 76 An. yamamai individuals from nine localities in South Korea showed that the observed number of alleles at each locus ranged from 3 to 26, the polymorphism information content was 0.2990-0.9014, the observed and expected heterozygosities were 0.3252-0.9076 and 0.2500-0.9054, respectively, and F was -0.654-0.520. The population-based F , F , R , and global Mantel tests all suggested that the An. yamamai populations were overall well-interconnected, suggesting that any population can be used as a genetic source for domestication. Nevertheless, STRUCTURE analyses using microsatellite data and mtDNA sequences indicated the presence of two genetic pools in many populations, although a plausible explanation for this observation requires further studies.
[Mh] Termos MeSH primário: Bombyx/genética
DNA Mitocondrial/genética
Repetições de Microssatélites
Polimorfismo Genético
[Mh] Termos MeSH secundário: Animais
Pool Gênico
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Mitochondrial)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170504
[Lr] Data última revisão:
170504
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170414
[St] Status:MEDLINE
[do] DOI:10.4238/gmr16029608


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[PMID]:28286223
[Au] Autor:Corrigan S; Maisano Delser P; Eddy C; Duffy C; Yang L; Li C; Bazinet AL; Mona S; Naylor GJ
[Ad] Endereço:Department of Biology, College of Charleston, Charleston SC, USA. Electronic address: corrigansl@cofc.edu.
[Ti] Título:Historical introgression drives pervasive mitochondrial admixture between two species of pelagic sharks.
[So] Source:Mol Phylogenet Evol;110:122-126, 2017 May.
[Is] ISSN:1095-9513
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:We use a genomic sampling of both nuclear and mitochondrial DNA markers to examine a pattern of genetic admixture between Carcharhinus galapagensis (Galapagos sharks) and Carcharhinus obscurus (dusky sharks), two well-known and closely related sharks that have been recognized as valid species for more than 100years. We describe widespread mitochondrial-nuclear discordance in which these species are readily distinguishable based on 2152 nuclear single nucleotide polymorphisms from 910 independent autosomal regions, but show pervasive mitochondrial admixture. The species are superficially morphologically cryptic as adults but show marked differences in internal anatomy, as well as niche separation. There was no indication of ongoing hybridization between the species. We conclude that the observed mitochondrial-nuclear discordance is likely due to historical mitochondrial introgression following a range expansion.
[Mh] Termos MeSH primário: Pool Gênico
Mitocôndrias/genética
Tubarões/genética
[Mh] Termos MeSH secundário: Animais
DNA Mitocondrial/genética
Ecossistema
Geografia
Haplótipos/genética
Filogenia
Especificidade da Espécie
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Mitochondrial)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170918
[Lr] Data última revisão:
170918
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170314
[St] Status:MEDLINE


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[PMID]:28233217
[Au] Autor:Dachapak S; Somta P; Poonchaivilaisak S; Yimram T; Srinives P
[Ad] Endereço:Department of Agronomy, Faculty of Agriculture at Kamphaeng Saen, Kasetsart University, Nakhon Pathom, 73140, Thailand.
[Ti] Título:Genetic diversity and structure of the zombi pea (Vigna vexillata (L.) A. Rich) gene pool based on SSR marker analysis.
[So] Source:Genetica;145(2):189-200, 2017 Apr.
[Is] ISSN:1573-6857
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Zombi pea (Vigna vexillata (L.) A. Rich) is an underutilized legume species and a useful gene source for resistance to biotic and abiotic stresses, although there is little understanding on its genetic diversity and structure. In this study, 422 (408 wild and 14 cultivated) accessions of zombi pea from diverse origins (201 from Africa, 126 from America, 85 from Australia, 5 from Asia and 5 from unknown origin) were analyzed with 20 simple sequence repeat (SSR) markers to determine its genetic diversity and genetic structure. The SSR markers detected 273 alleles in total with a mean of 13.6 alleles per locus. Polymorphism information content values of the markers varied from 0.58 to 0.90 with an average of 0.76. Overall gene diversity was 0.715. Gene diversity and average allelic richness was highest in Africa (0.749 and 8.08, respectively) and lowest in America (0.435 and 4.10, respectively). Nei's genetic distance analysis revealed that the highest distance was between wild Australia and cultivated Africa (0.559), followed by wild West Africa and wild Australia (0.415). STRUCTURE, neighbor-joining (NJ), and principal coordinate analyses consistently showed that these zombi pea accessions were clustered into three major groups, viz. America, Africa and Asia, and Australia. NJ tree also suggested that American and Australian accessions are originated from East African zombi peas, and that the cultivated accessions from Africa and Asia were genetically distinct, while those from America were clustered with some cultivated accessions from Africa. These results suggest that Africa is the center of origin and diversity of zombi pea, and that domestication of this pea took place more than once in different regions.
[Mh] Termos MeSH primário: Pool Gênico
Variação Genética
Repetições de Microssatélites/genética
Vigna/genética
[Mh] Termos MeSH secundário: África
Alelos
Austrália
Genética Populacional
Genótipo
Geografia
Filogenia
Especificidade da Espécie
Vigna/classificação
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1703
[Cu] Atualização por classe:171020
[Lr] Data última revisão:
171020
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170225
[St] Status:MEDLINE
[do] DOI:10.1007/s10709-017-9957-y


  6 / 796 MEDLINE  
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[PMID]:28178233
[Au] Autor:Jarvis DE; Ho YS; Lightfoot DJ; Schmöckel SM; Li B; Borm TJ; Ohyanagi H; Mineta K; Michell CT; Saber N; Kharbatia NM; Rupper RR; Sharp AR; Dally N; Boughton BA; Woo YH; Gao G; Schijlen EG; Guo X; Momin AA; Negrão S; Al-Babili S; Gehring C; Roessner U; Jung C; Murphy K; Arold ST; Gojobori T; Linden CG; van Loo EN; Jellen EN; Maughan PJ; Tester M
[Ad] Endereço:King Abdullah University of Science and Technology (KAUST), Biological and Environmental Sciences &Engineering Division (BESE), Thuwal, 23955-6900, Saudi Arabia.
[Ti] Título:The genome of Chenopodium quinoa.
[So] Source:Nature;542(7641):307-312, 2017 02 16.
[Is] ISSN:1476-4687
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Chenopodium quinoa (quinoa) is a highly nutritious grain identified as an important crop to improve world food security. Unfortunately, few resources are available to facilitate its genetic improvement. Here we report the assembly of a high-quality, chromosome-scale reference genome sequence for quinoa, which was produced using single-molecule real-time sequencing in combination with optical, chromosome-contact and genetic maps. We also report the sequencing of two diploids from the ancestral gene pools of quinoa, which enables the identification of sub-genomes in quinoa, and reduced-coverage genome sequences for 22 other samples of the allotetraploid goosefoot complex. The genome sequence facilitated the identification of the transcription factor likely to control the production of anti-nutritional triterpenoid saponins found in quinoa seeds, including a mutation that appears to cause alternative splicing and a premature stop codon in sweet quinoa strains. These genomic resources are an important first step towards the genetic improvement of quinoa.
[Mh] Termos MeSH primário: Chenopodium quinoa/genética
Genoma de Planta/genética
[Mh] Termos MeSH secundário: Processamento Alternativo/genética
Diploide
Evolução Molecular
Pool Gênico
Anotação de Sequência Molecular
Mutação
Poliploidia
Saponinas/biossíntese
Análise de Sequência de DNA
Fatores de Transcrição/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T; RESEARCH SUPPORT, U.S. GOV'T, NON-P.H.S.
[Nm] Nome de substância:
0 (Saponins); 0 (Transcription Factors)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170814
[Lr] Data última revisão:
170814
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170209
[St] Status:MEDLINE
[do] DOI:10.1038/nature21370


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[PMID]:28094447
[Au] Autor:Luzuriaga-Neira A; Villacís-Rivas G; Cueva-Castillo F; Escudero-Sánchez G; Ulloa-Nuñez A; Rubilar-Quezada M; Monteiro R; Miller MR; Beja-Pereira A
[Ad] Endereço:Centro de Investigação em Biodiversidade e Recursos Genéticos (CIBIO-InBIO), Universidade do Porto, Campus Agrário de Vairão, Rua Padre Armando Quintas 7, 4485-661, Vairão, Portugal.
[Ti] Título:On the origins and genetic diversity of South American chickens: one step closer.
[So] Source:Anim Genet;48(3):353-357, 2017 Jun.
[Is] ISSN:1365-2052
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Local chicken populations are a major source of food in the rural areas of South America. However, very little is known about their genetic composition and diversity. Here, we analyzed five populations from South America to investigate their maternal genetic origin and diversity, hoping to mitigate the lack of information on local chicken populations from this region. We also included three populations of chicken from the Iberian Peninsula and one from Easter Island, which are potential sources of the first chickens introduced in South America. The obtained sequencing data from South American chickens indicate the presence of four haplogroups (A, B, E and D) that can be further subdivided into nine sub-haplogroups. Of these, four (B1, D1a, E1a(b), E1b) were absent from local Iberian Peninsula chickens and one (D1a) was present only on Easter Island. The presence of the sub-haplogroups A1a(b) and E1a(b) in South America, previously only observed in Eastern Asia, and the significant population differentiation between Iberian Peninsula and South American populations, suggest a second maternal source of the extant genetic pool in South American chickens.
[Mh] Termos MeSH primário: Galinhas/genética
Variação Genética
Genética Populacional
[Mh] Termos MeSH secundário: Animais
DNA Mitocondrial/genética
Pool Gênico
Haplótipos
Filogenia
Análise de Sequência de DNA/veterinária
América do Sul
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Mitochondrial)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170524
[Lr] Data última revisão:
170524
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170118
[St] Status:MEDLINE
[do] DOI:10.1111/age.12537


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[PMID]:27744489
[Au] Autor:Dhaka N; Rout K; Yadava SK; Sodhi YS; Gupta V; Pental D; Pradhan AK
[Ad] Endereço:Department of Genetics, University of Delhi South Campus, Benito Juarez Road, New Delhi, 110021, India.
[Ti] Título:Genetic dissection of seed weight by QTL analysis and detection of allelic variation in Indian and east European gene pool lines of Brassica juncea.
[So] Source:Theor Appl Genet;130(2):293-307, 2017 Feb.
[Is] ISSN:1432-2242
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:KEY MESSAGE: Seed weight QTL identified in different populations were synthesized into consensus QTL which were shown to harbor candidate genes by in silico mapping. Allelic variation inferred would be useful in breeding B. juncea lines with high seed weight. Seed weight is an important yield influencing trait in oilseed Brassicas and is a multigenic trait. Among the oilseed Brassicas, Brassica juncea harbors the maximum phenotypic variation wherein thousand seed weight varies from around 2.0 g to more than 7.0 g. In this study, we have undertaken quantitative trait locus/quantitative trait loci (QTL) analysis of seed weight in B. juncea using four bi-parental doubled-haploid populations. These four populations were derived from six lines (three Indian and three east European lines) with parental phenotypic values for thousand seed weight ranging from 2.0 to 7.6 g in different environments. Multi-environment QTL analysis of the four populations identified a total of 65 QTL ranging from 10 to 25 in each population. Meta-analysis of these component QTL of the four populations identified six 'consensus' QTL (C-QTL) in A3, A7, A10 and B3 by merging 33 of the 65 component Tsw QTL from different bi-parental populations. Allelic diversity analysis of these six C-QTL showed that Indian lines, Pusajaikisan and Varuna, hold the most positive allele in all the six C-QTL. In silico mapping of candidate genes with the consensus QTL localized 11 genes known to influence seed weight in Arabidopsis thaliana and also showed conserved crucifer blocks harboring seed weight QTL between the A subgenomes of B. juncea and B. rapa. These findings pave the way for a better understanding of the genetics of seed weight in the oilseed crop B. juncea and reveal the scope available for improvement of seed weight through marker-assisted breeding.
[Mh] Termos MeSH primário: Pool Gênico
Mostardeira/genética
Locos de Características Quantitativas
Sementes/crescimento & desenvolvimento
[Mh] Termos MeSH secundário: Alelos
Mapeamento Cromossômico
Sequência Consenso
Epistasia Genética
Genética Populacional
Haploidia
Mostardeira/crescimento & desenvolvimento
Fenótipo
Sementes/genética
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170917
[Lr] Data última revisão:
170917
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161017
[St] Status:MEDLINE
[do] DOI:10.1007/s00122-016-2811-2


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[PMID]:27744413
[Au] Autor:Arauna LR; Mendoza-Revilla J; Mas-Sandoval A; Izaabel H; Bekada A; Benhamamouch S; Fadhlaoui-Zid K; Zalloua P; Hellenthal G; Comas D
[Ad] Endereço:Departament de Ciències Experimentals i de la Salut, Institute of Evolutionary Biology (CSIC-UPF), Universitat Pompeu Fabra, Barcelona, Spain.
[Ti] Título:Recent Historical Migrations Have Shaped the Gene Pool of Arabs and Berbers in North Africa.
[So] Source:Mol Biol Evol;34(2):318-329, 2017 Feb 01.
[Is] ISSN:1537-1719
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:North Africa is characterized by its diverse cultural and linguistic groups and its genetic heterogeneity. Genomic data has shown an amalgam of components mixed since pre-Holocean times. Though no differences have been found in uniparental and classical markers between Berbers and Arabs, the two main ethnic groups in the region, the scanty genomic data available have highlighted the singularity of Berbers. We characterize the genetic heterogeneity of North African groups, focusing on the putative differences of Berbers and Arabs, and estimate migration dates. We analyze genome-wide autosomal data in five Berber and six Arab groups, and compare them to Middle Easterns, sub-Saharans, and Europeans. Haplotype-based methods show a lack of correlation between geographical and genetic populations, and a high degree of genetic heterogeneity, without strong differences between Berbers and Arabs. Berbers enclose genetically diverse groups, from isolated endogamous groups with high autochthonous component frequencies, large homozygosity runs and low effective population sizes, to admixed groups with high frequencies of sub-Saharan and Middle Eastern components. Admixture time estimates show a complex pattern of recent historical migrations, with a peak around the 7th century C.E. coincident with the Arabization of the region; sub-Saharan migrations since the 1st century B.C. in agreement with Roman slave trade; and a strong migration in the 17th century C.E., coincident with a huge impact of the trans-Atlantic and trans-Saharan trade of sub-Saharan slaves in the Modern Era. The genetic complexity found should be taken into account when selecting reference groups in population genetics and biomedical studies.
[Mh] Termos MeSH primário: Grupo com Ancestrais do Continente Africano/genética
Árabes/genética
Pool Gênico
[Mh] Termos MeSH secundário: África do Norte
DNA Mitocondrial/genética
Grupo com Ancestrais do Continente Europeu/genética
Frequência do Gene
Variação Genética
Genética Populacional
Haplótipos
Migração Humana
Seres Humanos
Polimorfismo de Nucleotídeo Único
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Mitochondrial)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:171025
[Lr] Data última revisão:
171025
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161017
[St] Status:MEDLINE
[do] DOI:10.1093/molbev/msw218


  10 / 796 MEDLINE  
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[PMID]:27246811
[Au] Autor:Zhao J; Liu FE; Lin S; Liu ZZ; Sun ZY; Wu XM; Zhang HQ
[Ad] Endereço:a The Key Laboratory of Biomedical Information Engineering of Ministry of Education , Department of Biological Science and Engineering, School of Life Science and Technology, Xi'an Jiaotong University , Xi'an , PR China.
[Ti] Título:Investigation on maternal lineage of a Neolithic group from northern Shaanxi based on ancient DNA.
[So] Source:Mitochondrial DNA A DNA Mapp Seq Anal;28(5):732-739, 2017 Sep.
[Is] ISSN:2470-1408
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:A magnetic bead purification method was successfully used to extract ancient DNA from the skeletal remains of 10 specimens excavated from Wuzhuangguoliang (Wzhgl) site, which was located in northern Shaanxi. The multidimensional scaling (MDS) and analysis of molecular variance approach (AMOVA) revealed that ancient Wzhgl people bored a very high similarity to southern Han Chinese. By constructing the MJ-network of various modern people including Han Chinese and Japanese, the phylogenetic analysis indicated that the Wzhgl population had close maternal distance with ancient Shandong and Xinjiang people. These findings indicated that Wzhgl contributed to the gene pool of Han Chinese and modern Japanese. In addition, population migration and interflow between Wzhgl people and ancient Shandong or Xinjiang probably occurred in Neolithic period.
[Mh] Termos MeSH primário: Grupo com Ancestrais do Continente Asiático/genética
DNA Antigo/análise
DNA Mitocondrial/análise
Análise de Sequência de DNA/métodos
[Mh] Termos MeSH secundário: Grupo com Ancestrais do Continente Asiático/etnologia
China/etnologia
Pool Gênico
Seres Humanos
Japão/etnologia
Filogenia
Análise de Componente Principal
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Ancient); 0 (DNA, Mitochondrial)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170919
[Lr] Data última revisão:
170919
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160602
[St] Status:MEDLINE
[do] DOI:10.1080/24701394.2016.1177039



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