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  1 / 15079 MEDLINE  
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[PMID]:28448633
[Au] Autor:Scoffield JA; Duan D; Zhu F; Wu H
[Ad] Endereço:Department of Pediatric Dentistry, School of Dentistry, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
[Ti] Título:A commensal streptococcus hijacks a Pseudomonas aeruginosa exopolysaccharide to promote biofilm formation.
[So] Source:PLoS Pathog;13(4):e1006300, 2017 Apr.
[Is] ISSN:1553-7374
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Pseudomonas aeruginosa causes devastating chronic pulmonary infections in cystic fibrosis (CF) patients. Although the CF airway is inhabited by diverse species of microorganisms interlaced within a biofilm, many studies focus on the sole contribution of P. aeruginosa pathogenesis in CF morbidity. More recently, oral commensal streptococci have been identified as cohabitants of the CF lung, but few studies have explored the role these bacteria play within the CF biofilm. We examined the interaction between P. aeruginosa and oral commensal streptococci within a dual species biofilm. Here we report that the CF P. aeruginosa isolate, FRD1, enhances biofilm formation and colonization of Drosophila melanogaster by the oral commensal Streptococcus parasanguinis. Moreover, production of the P. aeruginosa exopolysaccharide, alginate, is required for the promotion of S. parasanguinis biofilm formation and colonization. However, P. aeruginosa is not promoted in the dual species biofilm. Furthermore, we show that the streptococcal adhesin, BapA1, mediates alginate-dependent enhancement of the S. parasanguinis biofilm in vitro, and BapA1 along with another adhesin, Fap1, are required for the in vivo colonization of S. parasanguinis in the presence of FRD1. Taken together, our study highlights a new association between streptococcal adhesins and P. aeruginosa alginate, and reveals a mechanism by which S. parasanguinis potentially colonizes the CF lung and interferes with the pathogenesis of P. aeruginosa.
[Mh] Termos MeSH primário: Biofilmes
Fibrose Cística/microbiologia
Polissacarídeos Bacterianos/metabolismo
Infecções por Pseudomonas/microbiologia
Pseudomonas aeruginosa/fisiologia
[Mh] Termos MeSH secundário: Adesinas Bacterianas/genética
Adesinas Bacterianas/metabolismo
Animais
Drosophila melanogaster
Seres Humanos
Pseudomonas aeruginosa/genética
Pseudomonas aeruginosa/crescimento & desenvolvimento
Pseudomonas aeruginosa/isolamento & purificação
Sistema Respiratório/microbiologia
Simbiose
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Adhesins, Bacterial); 0 (Polysaccharides, Bacterial); 128531-82-8 (exopolysaccharide, Pseudomonas)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:180306
[Lr] Data última revisão:
180306
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170428
[St] Status:MEDLINE
[do] DOI:10.1371/journal.ppat.1006300


  2 / 15079 MEDLINE  
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[PMID]:29367525
[Au] Autor:Tanemoto S; Sujino T; Kanai T
[Ad] Endereço:Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine.
[Ti] Título:[Intestinal immune response is regulated by gut microbe].
[So] Source:Nihon Rinsho Meneki Gakkai Kaishi;40(6):408-415, 2017.
[Is] ISSN:1349-7413
[Cp] País de publicação:Japan
[La] Idioma:jpn
[Ab] Resumo:  Human Intestine has a diverse population of bacteria which induces pathogens to disrupt not only the intestinal homeostasis but whole body immune systems. Dysbiosis, the abnormal proliferation and reduction of the microbiota, breaks down the homeostasis of the immunity and metabolisms in the host. The evolution of the microbiota analysis technology contributed to reveal the molecular biological complex interaction between the microbiota and its host systemically as well as locally. Because several diseases are caused by the dysbiosis, fecal transplantation would be the new therapeutic target for them. It has been investigated in some intestinal diseases such as CD infection, or inflammatory bowel disease. Here, we review these symbiotic interactions and the current state for the clinical application.
[Mh] Termos MeSH primário: Microbioma Gastrointestinal/imunologia
Microbioma Gastrointestinal/fisiologia
Intestinos/imunologia
Intestinos/microbiologia
[Mh] Termos MeSH secundário: Disbiose/imunologia
Disbiose/microbiologia
Disbiose/terapia
Transplante de Microbiota Fecal
Homeostase/imunologia
Seres Humanos
Doenças Inflamatórias Intestinais/imunologia
Doenças Inflamatórias Intestinais/microbiologia
Doenças Inflamatórias Intestinais/terapia
Simbiose
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180227
[Lr] Data última revisão:
180227
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180126
[St] Status:MEDLINE
[do] DOI:10.2177/jsci.40.408


  3 / 15079 MEDLINE  
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[PMID]:29241035
[Au] Autor:Lopez CA; Skaar EP
[Ad] Endereço:Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.
[Ti] Título:Crossed Wires: Interspecies Interference Blocks Pathogen Colonization.
[So] Source:Cell Host Microbe;22(6):721-723, 2017 12 13.
[Is] ISSN:1934-6069
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Commensal bacteria protect against invading pathogens using many strategies. In this issue of Cell Host & Microbe, Paharik et al. (2017) find that a commensal blocks Staphylococcus aureus colonization by producing a signal to shut down virulence.
[Mh] Termos MeSH primário: Infecções Estafilocócicas/microbiologia
Staphylococcus aureus
[Mh] Termos MeSH secundário: Seres Humanos
Simbiose
Virulência
Fatores de Virulência
[Pt] Tipo de publicação:JOURNAL ARTICLE; COMMENT
[Nm] Nome de substância:
0 (Virulence Factors)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180227
[Lr] Data última revisão:
180227
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171215
[St] Status:MEDLINE


  4 / 15079 MEDLINE  
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[PMID]:29346449
[Au] Autor:Chrostek E; Teixeira L
[Ad] Endereço:Instituto Gulbenkian de Ciência, Oeiras, Portugal.
[Ti] Título:Within host selection for faster replicating bacterial symbionts.
[So] Source:PLoS One;13(1):e0191530, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Wolbachia is a widespread, intracellular symbiont of arthropods, able to induce reproductive distortions and antiviral protection in insects. Wolbachia can also be pathogenic, as is the case with wMelPop, a virulent variant of the endosymbiont of Drosophila melanogaster. An extensive genomic amplification of the 20kb region encompassing eight Wolbachia genes, called Octomom, is responsible for wMelPop virulence. The Octomom copy number in wMelPop can be highly variable between individual D. melanogaster flies, even when comparing siblings arising from a single female. Moreover, Octomom copy number can change rapidly between generations. These data suggest an intra-host variability in Octomom copy number between Wolbachia cells. Since wMelPop Wolbachia with different Octomom copy numbers grow at different rates, we hypothesized that selection could act on this intra-host variability. Here we tested if total Octomom copy number changes during the lifespan of individual Drosophila hosts, revealing selection for different Wolbachia populations. We performed a time course analysis of Octomom amplification in flies whose mothers were controlled for Octomom copy number. We show that despite the Octomom copy number being relatively stable it increases slightly throughout D. melanogaster adult life. This indicates that there is selection acting on the intra-host variation in the Octomom copy number over the lifespan of individual hosts. This within host selection for faster replicating bacterial symbionts may be in conflict with between host selection against highly pathogenic Wolbachia.
[Mh] Termos MeSH primário: Drosophila melanogaster/microbiologia
Interações Hospedeiro-Patógeno
Simbiose
Wolbachia/crescimento & desenvolvimento
[Mh] Termos MeSH secundário: Animais
Genes Bacterianos
Virulência/genética
Wolbachia/genética
Wolbachia/patogenicidade
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180223
[Lr] Data última revisão:
180223
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180119
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0191530


  5 / 15079 MEDLINE  
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[PMID]:29202309
[Au] Autor:Grimonprez A; Molza A; Laurent MCZ; Mansot JL; Gros O
[Ad] Endereço:Sorbonne Universités, UPMC Univ Paris 06, Univ Antilles Guyane, Univ Nice Sophia Antipolis, CNRS, Evolution Paris Seine-Institut de Biologie Paris Seine (EPS-IBPS), 75005 Paris, France. Electronic address: Adrien.Grimonprez@etu.univ-antilles.fr.
[Ti] Título:Thioautotrophic ectosymbiosis in Pseudovorticella sp., a peritrich ciliate species colonizing wood falls in marine mangrove.
[So] Source:Eur J Protistol;62:43-55, 2018 Feb.
[Is] ISSN:1618-0429
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Ciliates represent a diversified group of protists known to establish symbioses with prokaryotic micro-organisms. They are mainly phagotrophs and symbiotic relationships with bacteria can give them an important advantage in chemosynthetic environments. The aim of this study is to describe the thiotrophic association that occurs between the peritrich ciliate Pseudovorticella sp. and potential sulfur-oxidizing bacteria. Investigations at microscopic scale (LM, SEM, TEM) showed ectosymbiotic bacteria covering the surface of the body of Pseudovorticella sp. According to 16S rDNA phylogenetic analysis, these ectosymbiotic bacteria belong to γ-proteobacteria and are phylogenetically close to the symbiont of the recently described Zoothamnium ignavum, which inhabits shallow-water wood falls. FISH experiments, using symbiont specific probes, clearly indicate that these ectosymbiotic bacteria are also ingested into food vacuoles. Electron lucent granules observed in TEM in the cytoplasm of the ectosymbiotic bacteria have been identified as sulfur granules by Raman microspectrometry analyses. Raman microspectrometry analyses confirmed the thiotrophic nature of this relationship already suggested by the results obtained by TEM and phylogeny. A complete sulfur map was then performed to investigate the sulfur distribution in the zooid. Results show that the relationship between this protist and its bacterial partner is a thiotrophic ectosymbiosis.
[Mh] Termos MeSH primário: Organismos Aquáticos/fisiologia
Fenômenos Fisiológicos Bacterianos
Oligoimenóforos/microbiologia
Simbiose
[Mh] Termos MeSH secundário: Organismos Aquáticos/genética
Bactérias/genética
Bactérias/ultraestrutura
DNA Ribossômico/genética
Oligoimenóforos/genética
Oligoimenóforos/fisiologia
Oligoimenóforos/ultraestrutura
Filogenia
RNA Ribossômico 16S/genética
Madeira/microbiologia
Madeira/parasitologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Ribosomal); 0 (RNA, Ribosomal, 16S)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180223
[Lr] Data última revisão:
180223
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171205
[St] Status:MEDLINE


  6 / 15079 MEDLINE  
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[PMID]:29358578
[Au] Autor:Bonneau M; Atyame C; Beji M; Justy F; Cohen-Gonsaud M; Sicard M; Weill M
[Ad] Endereço:Institut des Sciences de l'Evolution de Montpellier (ISEM), UMR CNRS-IRD-EPHE-Université de Montpellier, Place Eugène Bataillon, 34095, Montpellier, France.
[Ti] Título:Culex pipiens crossing type diversity is governed by an amplified and polymorphic operon of Wolbachia.
[So] Source:Nat Commun;9(1):319, 2018 01 22.
[Is] ISSN:2041-1723
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Culex pipiens mosquitoes are infected with Wolbachia (wPip) that cause an important diversity of cytoplasmic incompatibilities (CIs). Functional transgenic studies have implicated the cidA-cidB operon from wPip and its homolog in wMel in CI between infected Drosophila males and uninfected females. However, the genetic basis of the CI diversity induced by different Wolbachia strains was unknown. We show here that the remarkable diversity of CI in the C. pipiens complex is due to the presence, in all tested wPip genomes, of several copies of the cidA-cidB operon, which undergoes diversification through recombination events. In 183 isofemale lines of C. pipiens collected worldwide, specific variations of the cidA-cidB gene repertoires are found to match crossing types. The diversification of cidA-cidB is consistent with the hypothesis of a toxin-antitoxin system in which the gene cidB co-diversifies with the gene cidA, particularly in putative domains of reciprocal interactions.
[Mh] Termos MeSH primário: Proteínas de Bactérias/genética
Culex/microbiologia
Drosophila melanogaster/microbiologia
Genoma Bacteriano
Óperon
Wolbachia/genética
[Mh] Termos MeSH secundário: Sequência de Aminoácidos
Animais
Proteínas de Bactérias/metabolismo
Sequência de Bases
Cruzamentos Genéticos
Culex/genética
Drosophila melanogaster/genética
Feminino
Especificidade de Hospedeiro
Masculino
Polimorfismo Genético
Alinhamento de Sequência
Homologia de Sequência de Aminoácidos
Simbiose/genética
Sistemas Toxina-Antitoxina/genética
Wolbachia/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Bacterial Proteins)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180222
[Lr] Data última revisão:
180222
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180124
[St] Status:MEDLINE
[do] DOI:10.1038/s41467-017-02749-w


  7 / 15079 MEDLINE  
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[PMID]:29321473
[Au] Autor:Zobel M; Davison J; Edwards ME; Brochmann C; Coissac E; Taberlet P; Willerslev E; Moora M
[Ad] Endereço:Department of Botany, Institute of Ecology and Earth Sciences, University of Tartu, 40 Lai Street, 51005, Tartu, Estonia.
[Ti] Título:Ancient environmental DNA reveals shifts in dominant mutualisms during the late Quaternary.
[So] Source:Nat Commun;9(1):139, 2018 01 10.
[Is] ISSN:2041-1723
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:DNA-based snapshots of ancient vegetation have shown that the composition of high-latitude plant communities changed considerably during the late Quaternary. However, parallel changes in biotic interactions remain largely uninvestigated. Here we show how mutualisms involving plants and heterotrophic organisms varied during the last 50,000 years. During 50-25 ka BP, a cool period featuring stadial-interstadial fluctuations, arbuscular mycorrhizal and non-N-fixing plants predominated. During 25-15 ka BP, a cold, dry interval, the representation of ectomycorrhizal, non-mycorrhizal and facultatively mycorrhizal plants increased, while that of N-fixing plants decreased further. From 15 ka BP, which marks the transition to and establishment of the Holocene interglaciation, representation of arbuscular mycorrhizal plants decreased further, while that of ectomycorrhizal, non-mycorrhizal, N-fixing and wind-pollinated plants increased. These changes in the mutualist trait structure of vegetation may reflect responses to historical environmental conditions that are without current analogue, or biogeographic processes, such as spatial decoupling of mutualist partners.
[Mh] Termos MeSH primário: Evolução Biológica
DNA Antigo/análise
Micorrizas/genética
Plantas/genética
Simbiose
[Mh] Termos MeSH secundário: Ciclo do Carbono/fisiologia
Dióxido de Carbono/química
Dióxido de Carbono/metabolismo
Clima
Ecossistema
Meio Ambiente
História Antiga
Micorrizas/classificação
Nitrogênio/química
Nitrogênio/metabolismo
Fixação de Nitrogênio/fisiologia
Plantas/classificação
Polinização/fisiologia
Datação Radiométrica
[Pt] Tipo de publicação:HISTORICAL ARTICLE; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (DNA, Ancient); 142M471B3J (Carbon Dioxide); N762921K75 (Nitrogen)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180222
[Lr] Data última revisão:
180222
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180112
[St] Status:MEDLINE
[do] DOI:10.1038/s41467-017-02421-3


  8 / 15079 MEDLINE  
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[PMID]:29292470
[Au] Autor:Kehelpannala C; Kumar NS; Jayasinghe L; Araya H; Fujimoto Y
[Ad] Endereço:National Institute of Fundamental Studies, Hantana Road, Kandy, Sri Lanka.
[Ti] Título:Naphthoquinone Metabolites Produced by Monacrosporium ambrosium, the Ectosymbiotic Fungus of Tea Shot-Hole Borer, Euwallacea fornicatus, in Stems of Tea, Camellia sinensis.
[So] Source:J Chem Ecol;44(1):95-101, 2018 Jan.
[Is] ISSN:1573-1561
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The tea shot-hole borer beetle (TSHB, Euwallacea fornicatus) causes serious damage in plantations of tea, Camellia sinensis var. assamica, in Sri Lanka and South India. TSHB is found in symbiotic association with the ambrosia fungus, Monacrosporium ambrosium (syn. Fusarium ambrosium), in galleries located within stems of tea bushes. M. ambrosium is known to be the sole food source of TSHB. Six naphthoquinones produced during spore germination in a laboratory culture broth of M. ambrosium were isolated and identified as dihydroanhydrojavanicin, anhydrojavanicin, javanicin, 5,8-dihydroxy-2-methyl-3-(2-oxopropyl)naphthalene-1,4-dione, anhydrofusarubin and solaniol. Chloroform extracts of tea stems with red-colored galleries occupied by TSHB contained UV active compounds similar to the above naphthoquinones. Laboratory assays demonstrated that the combined ethyl acetate extracts of the fungal culture broth and mycelium inhibited the growth of endophytic fungi Pestalotiopsis camelliae and Phoma multirostrata, which were also isolated from tea stems. Thus, pigmented naphthoquinones secreted by M. ambrosium during spore germination may prevent other fungi from invading TSHB galleries in tea stems. The antifungal nature of the naphthoquinone extract suggests that it protects the habitat of TSHB. We propose that the TSHB fungal ectosymbiont M. ambrosium provides not only the food and sterol skeleton necessary for the development of the beetle during its larval stages, but also serves as a producer of fungal inhibitors that help to preserve the purity of the fungal garden of TSHB.
[Mh] Termos MeSH primário: Ascomicetos/química
Camellia sinensis/microbiologia
Coleópteros/microbiologia
Naftoquinonas/análise
[Mh] Termos MeSH secundário: Animais
Antifúngicos/química
Antifúngicos/isolamento & purificação
Antifúngicos/farmacologia
Ascomicetos/efeitos dos fármacos
Ascomicetos/fisiologia
Camellia sinensis/crescimento & desenvolvimento
Clorofórmio/química
Ecossistema
Espectroscopia de Ressonância Magnética
Naftoquinonas/isolamento & purificação
Naftoquinonas/farmacologia
Caules de Planta/química
Caules de Planta/microbiologia
Esporos Fúngicos/química
Esporos Fúngicos/crescimento & desenvolvimento
Simbiose
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antifungal Agents); 0 (Naphthoquinones); 7V31YC746X (Chloroform)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180221
[Lr] Data última revisão:
180221
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180103
[St] Status:MEDLINE
[do] DOI:10.1007/s10886-017-0913-1


  9 / 15079 MEDLINE  
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[PMID]:29250744
[Au] Autor:Yadav P; Desireddy S; Kasinathan S; Bessière JM; Borges RM
[Ad] Endereço:Centre for Ecological Sciences, Indian Institute of Science, Bangalore, 560012, India.
[Ti] Título:History Matters: Oviposition Resource Acceptance in an Exploiter of a Nursery Pollination Mutualism.
[So] Source:J Chem Ecol;44(1):18-28, 2018 Jan.
[Is] ISSN:1573-1561
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:In the fig-fig wasp nursery pollination system, parasitic wasps, such as gallers and parasitoids that oviposit from the exterior into the fig syconium (globular, enclosed inflorescence) are expected to use a variety of chemical cues for successful location of their hidden hosts. Behavioral assays were performed with freshly eclosed naive galler wasps. Syconia with different oviposition histories, i.e. with or without prior oviposition, were presented to wasps in no-choice assays and the time taken to the first oviposition attempt was recorded. The wasps exhibited a preference for syconia previously exposed to conspecifics for oviposition over unexposed syconia. Additionally, syconia exposed to oviposition by heterospecific wasps were also preferred for oviposition over unexposed syconia indicating that wasps recognise and respond to interspecific cues. Wasps also aggregated for oviposition on syconia previously exposed to oviposition by conspecifics. We investigated chemical cues that wasps may employ in accepting an oviposition resource by analyzing syconial volatile profiles, chemical footprints left by wasps on syconia, and syconial surface hydrocarbons. The volatile profile of a syconium is influenced by the identity of wasps developing within and may be used to identify suitable host syconia at long range whereas close range preference seems to exploit wasp footprints that alter syconium surface hydrocarbon profiles. These cues act as indicators of the oviposition history of the syconium, thereby helping wasps in their oviposition decisions.
[Mh] Termos MeSH primário: Polinização/fisiologia
Vespas/fisiologia
[Mh] Termos MeSH secundário: Animais
Frutas/química
Frutas/metabolismo
Frutas/parasitologia
Oviposição/fisiologia
Plantas/química
Plantas/metabolismo
Plantas/parasitologia
Simbiose
Compostos Orgânicos Voláteis/química
Vespas/crescimento & desenvolvimento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Volatile Organic Compounds)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180221
[Lr] Data última revisão:
180221
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171219
[St] Status:MEDLINE
[do] DOI:10.1007/s10886-017-0914-0


  10 / 15079 MEDLINE  
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[PMID]:28464391
[Au] Autor:Lawrence SA; Floge SA; Davy JE; Davy SK; Wilson WH
[Ad] Endereço:School of Biological Sciences, Victoria University of Wellington, Wellington, 6140, New Zealand.
[Ti] Título:Exploratory analysis of Symbiodinium transcriptomes reveals potential latent infection by large dsDNA viruses.
[So] Source:Environ Microbiol;19(10):3909-3919, 2017 Oct.
[Is] ISSN:1462-2920
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Coral reefs are in decline worldwide. Much of this decline is attributable to mass coral bleaching events and disease outbreaks, both of which are linked to anthropogenic climate change. Despite increased research effort, much remains unknown about these phenomena, especially the causative agents of many coral diseases. In particular, coral-associated viruses have received little attention, and their potential roles in coral diseases are largely unknown. Previous microscopy studies have produced evidence of viral infections in Symbiodinium, the endosymbiotic algae critical for coral survival, and more recently molecular evidence of Symbiodinium-infecting viruses has emerged from metagenomic studies of corals. Here, we took an exploratory whole-transcriptome approach to virus gene discovery in three different Symbiodinium cultures. An array of virus-like genes was found in each of the transcriptomes, with the majority apparently belonging to the nucleocytoplasmic large DNA viruses. Upregulation of virus-like gene expression following stress experiments indicated that Symbiodinium cells may host latent or persistent viral infections that are induced via stress. This was supported by analysis of host gene expression, which showed changes consistent with viral infection after exposure to stress. If these results can be replicated in Symbiodinium cells in hospite, they could help to explain the breakdown of the coral-Symbiodinium symbiosis, and possibly some of the numerous coral diseases that have yet to be assigned a causative agent.
[Mh] Termos MeSH primário: Vírus de DNA/genética
Dinoflagelados/genética
Dinoflagelados/virologia
Transcriptoma/genética
[Mh] Termos MeSH secundário: Animais
Antozoários/fisiologia
Mudança Climática
Recifes de Corais
Simbiose/genética
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180221
[Lr] Data última revisão:
180221
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170503
[St] Status:MEDLINE
[do] DOI:10.1111/1462-2920.13782



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