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Referências encontradas : 464 [refinar]
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[PMID]:28818833
[Au] Autor:Inouye CY; Bae CL; Hayes KN
[Ad] Endereço:Department of Biological Sciences, California State University, East Bay, Hayward, California; caron.inouye@csueastbay.edu.
[Ti] Título:Using whiteboards to support college students' learning of complex physiological concepts.
[So] Source:Adv Physiol Educ;41(3):478-484, 2017 Sep 01.
[Is] ISSN:1522-1229
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Research underscores the importance of retrieval-based practice and application of knowledge for meaningful learning. However, the didactic lecture format continues to persist in traditional university physiology courses. A strategy called whiteboarding, where students use handheld dry erase boards and work in small groups to actively retrieve, discuss, and apply concepts presented in the lecture, has the potential to address challenges associated with actively engaging students in science courses for greater learning. The purpose of this study was to empirically examine the potential benefits of whiteboarding for increasing students' understanding of animal physiology concepts. Student performance on physiology questions assessing concepts taught using lecture only vs. concepts taught using lecture and whiteboarding were compared within the term that whiteboarding was used, as well as across whiteboard and lecture-only terms taught by the same instructor. Results showed that when whiteboarding was incorporated in the course, student performance on items that assessed concepts corresponding to the whiteboarding activities were significantly higher compared with performance on items that assessed concepts taught through lecture only. These patterns in student performance were found within and across terms. Taken together, findings point to whiteboarding as an effective tool that can be integrated in traditional lecture courses to promote students' understanding of physiology.
[Mh] Termos MeSH primário: Educação/métodos
Fisiologia/educação
Universidades/normas
[Mh] Termos MeSH secundário: Animais
Compreensão
Educação/normas
Educação/tendências
Seres Humanos
Aprendizagem
Fenômenos Fisiológicos
Fisiologia/tendências
Estudantes
Universidades/tendências
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171103
[Lr] Data última revisão:
171103
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170819
[St] Status:MEDLINE
[do] DOI:10.1152/advan.00202.2016


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[PMID]:28442478
[Au] Autor:Michael J; Martinkova P; McFarland J; Wright A; Cliff W; Modell H; Wenderoth MP
[Ad] Endereço:Department of Molecular Biophysics and Physiology, Rush Medical College, Chicago, Illinois; jmichael40@gmail.com.
[Ti] Título:Validating a conceptual framework for the core concept of "cell-cell communication".
[So] Source:Adv Physiol Educ;41(2):260-265, 2017 Jun 01.
[Is] ISSN:1522-1229
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:We have created and validated a conceptual framework for the core physiology concept of "cell-cell communication." The conceptual framework is composed of 51 items arranged in a hierarchy that is, in some instances, four levels deep. We have validated it with input from faculty who teach at a wide variety of institutional types. All items making up the framework were deemed essential to moderately important. However, some of the main ideas were clearly judged to be more important than others. Furthermore, the lower in the hierarchy an item is, the less important it is thought to be. Finally, there was no significant difference in the ratings given by faculty at different types of institutions.
[Mh] Termos MeSH primário: Comunicação Celular
Modelos Biológicos
Fenômenos Fisiológicos
Fisiologia/educação
[Mh] Termos MeSH secundário: Docentes
Seres Humanos
Reprodutibilidade dos Testes
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171103
[Lr] Data última revisão:
171103
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170427
[St] Status:MEDLINE
[do] DOI:10.1152/advan.00100.2016


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[PMID]:28414779
[Au] Autor:Ye J; Wen B
[Ad] Endereço:Center for Integrative Conservation, Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences, Mengla, Yunnan, China.
[Ti] Título:Seed germination in relation to the invasiveness in spiny amaranth and edible amaranth in Xishuangbanna, SW China.
[So] Source:PLoS One;12(4):e0175948, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Both spiny and edible amaranths (Amaranthus spinosus and A. tricolor) are exotic annuals in China that produce numerous small seeds every year. Spiny amaranth has become a successful invader and a troublesome weed in Xishuangbanna, but edible amaranth has not, although it is widely grown as a vegetable there. As seed germination is one of the most important life-stages contributing to the ability of a plant to become invasive, we conducted experiments to compare the effects of high temperature and water stress on seed germination in two varieties each of spiny amaranth and edible amaranth. Overall, the seeds of both amaranth species exhibited adaptation to high temperature and water stress, including tolerance to ground temperatures of 70°C for air-dried seeds, which is consistent with their behavior in their native ranges in the tropics. As expected, the invasive spiny amaranth seeds exhibited higher tolerance to both continuous and daily periodic high-temperature treatment at 45°C, and to imbibition-desiccation treatment, compared to edible amaranth seeds. Unexpectedly, edible amaranth seeds exhibited higher germination at extreme temperatures (10°C, 15°C, and 40°C), and at lower water potential (below -0.6 MPa). It is likely that cultivation of edible amaranth has selected seed traits that include rapid germination and germination under stressful conditions, either of which, under natural conditions, may result in the death of most germinating edible amaranth seeds and prevent them from becoming invasive weeds in Xishuangbanna. This study suggests that rapid germination and high germination under stress conditions-excellent seed traits for crops and for many invasive species-might be a disadvantage under natural conditions if these traits are asynchronous with natural local conditions that support successful germination.
[Mh] Termos MeSH primário: Amaranthus/crescimento & desenvolvimento
Germinação/fisiologia
Plantas Daninhas/crescimento & desenvolvimento
Sementes/crescimento & desenvolvimento
[Mh] Termos MeSH secundário: Adaptação Fisiológica/fisiologia
Fenômenos Biológicos
China
Desidratação/fisiopatologia
Temperatura Alta
Espécies Introduzidas
Fenômenos Fisiológicos/fisiologia
Água
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
059QF0KO0R (Water)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170505
[Lr] Data última revisão:
170505
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170418
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0175948


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[PMID]:28345793
[Au] Autor:Ehrmann M; Kaiser M
[Ad] Endereço:Microbiology, ZMB, Faculty of Biology, University of Duisburg-Essen, Universitätsstrasse 2, 45117, Essen, Germany.
[Ti] Título:Small Molecules from Deep within the Gut.
[So] Source:Chembiochem;18(11):967-968, 2017 Jun 01.
[Is] ISSN:1439-7633
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Although the influence of the human microbiome on host functions is widely recognized, the underlying molecular mechanisms are still largely unknown. A recent study by the Fischbach group now provides an experimental workflow for characterizing and evaluating the impact of microbiome-derived small molecules on host physiology.
[Mh] Termos MeSH primário: Microbiota/fisiologia
Fenômenos Fisiológicos/fisiologia
[Mh] Termos MeSH secundário: Seres Humanos
Metagenômica/métodos
Família Multigênica
Peptídeo Sintases/análise
Peptídeo Sintases/genética
Inibidores de Proteases
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Protease Inhibitors); EC 6.3.2.- (Peptide Synthases); EC 6.3.2.- (non-ribosomal peptide synthase)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170721
[Lr] Data última revisão:
170721
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170328
[St] Status:MEDLINE
[do] DOI:10.1002/cbic.201700165


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[PMID]:28328950
[Au] Autor:Schmitz S; Tacke S; Guth B; Henke J
[Ad] Endereço:Department of Nonclinical Drug Safety, Biological Laboratory Service, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany.
[Ti] Título:Repeated anaesthesia with isoflurane and medetomidine-midazolam-fentanyl in guinea pigs and its influence on physiological parameters.
[So] Source:PLoS One;12(3):e0174423, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Repeated anaesthesia may be required in experimental protocols and in daily veterinary practice, but anaesthesia is known to alter physiological parameters in GPs (Cavia porcellus, GPs). This study investigated the effects of repeated anaesthesia with either medetomidine-midazolam-fentanyl (MMF) or isoflurane (Iso) on physiological parameters in the GP. Twelve GPs were repeatedly administered with MMF or Iso in two anaesthesia sets. One set consisted of six 40-min anaesthesias, performed over 3 weeks (2 per week); the anaesthetic used first was randomized. Prior to Iso anaesthesia, atropine was injected. MMF anaesthesia was antagonized with AFN (atipamezole-flumazenil-naloxone). Abdominally implanted radio-telemetry devices recorded the mean arterial blood pressure (MAP), heart rate (HR) and core body temperature continuously. Additionally, respiratory rate, blood glucose and body weight were assessed. An operable state could be achieved and maintained for 40 min in all GPs. During the surgical tolerance with MMF, the GPs showed a large MAP range between the individuals. In the MMF wake- up phase, the time was shortened until the righting reflex (RR) returned and that occurred at lower MAP and HR values. Repeated Iso anaesthesia led to an increasing HR during induction (anaesthesias 2-6), non-surgical tolerance (anaesthesias 3-6) and surgical tolerance (anaesthesias 4, 6). Both anaesthetics may be used repeatedly, as repeating the anaesthesias resulted in only slightly different physiological parameters, compared to those seen with single anaesthesias. The regular atropine premedication induced HR increases and repeated MMF anaesthesia resulted in a metabolism increase which led to the faster return of RR. Nevertheless, Iso's anaesthesia effects of strong respiratory depression and severe hypotension remained. Based on this increased anaesthesia risk with Iso, MMF anaesthesia is preferable for repeated use in GPs.
[Mh] Termos MeSH primário: Fentanila/administração & dosagem
Isoflurano/administração & dosagem
Medetomidina/administração & dosagem
Midazolam/administração & dosagem
Fenômenos Fisiológicos/efeitos dos fármacos
[Mh] Termos MeSH secundário: Anestesia/métodos
Anestésicos Combinados/administração & dosagem
Animais
Glicemia/efeitos dos fármacos
Pressão Sanguínea/efeitos dos fármacos
Cobaias
Frequência Cardíaca/efeitos dos fármacos
Masculino
Taxa Respiratória/efeitos dos fármacos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anesthetics, Combined); 0 (Blood Glucose); CYS9AKD70P (Isoflurane); MR15E85MQM (Medetomidine); R60L0SM5BC (Midazolam); UF599785JZ (Fentanyl)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170822
[Lr] Data última revisão:
170822
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170323
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0174423


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[PMID]:28268055
[Au] Autor:Engwall M; Fridh I; Jutengren G; Bergbom I; Sterner A; Lindahl B
[Ad] Endereço:Faculty of Caring Sciences, Work Life & Social Welfare, University of Borås, SE-50190 Borås, Sweden; Sahlgrenska Academy, Gothenburg University and the Institute of Health & Caring Sciences, Arvid Wallgrens Backe 1, SE 41346 Gothenburg, Sweden. Electronic address: marie.engwall@hb.se.
[Ti] Título:The effect of cycled lighting in the intensive care unit on sleep, activity and physiological parameters: A pilot study.
[So] Source:Intensive Crit Care Nurs;41:26-32, 2017 Aug.
[Is] ISSN:1532-4036
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Patients in intensive care suffer from severe illnesses or injuries and from symptoms related to care and treatments. Environmental factors, such as lighting at night, can disturb patients' circadian rhythms. The aim was to investigate whether patients displayed circadian rhythms and whether a cycled lighting intervention would impact it. In this pilot study (N=60), a cycled lighting intervention in a two-bed patient room was conducted. An ordinary hospital room functioned as the control. Patient activity, heart rate, mean arterial pressure and body temperature were recorded. All data were collected during the patients' final 24h in the intensive care unit. There was a significant difference between day and night patient activity within but not between conditions. Heart rates differed between day and night significantly for patients in the ordinary room but not in the intervention room or between conditions. Body temperature was lowest at night for all patients with no significant difference between conditions. Patients in both conditions had a natural circadian rhythm; and the cycled lighting intervention showed no significant impact. As the sample size was small, a larger repeated measures study should be conducted to determine if other types of lighting or environmental factors can impact patients' well-being.
[Mh] Termos MeSH primário: Iluminação/efeitos adversos
Fenômenos Fisiológicos
Sono
[Mh] Termos MeSH secundário: Idoso
Ritmo Circadiano
Feminino
Seres Humanos
Unidades de Terapia Intensiva/organização & administração
Unidades de Terapia Intensiva/normas
Masculino
Meia-Idade
Projetos Piloto
Fatores de Tempo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171002
[Lr] Data última revisão:
171002
[Sb] Subgrupo de revista:N
[Da] Data de entrada para processamento:170308
[St] Status:MEDLINE


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[PMID]:28153443
[Au] Autor:Pecquerie L; Lika K
[Ad] Endereço:Institut de Recherche pour le Développement, Laboratoire des Sciences de l'Environnement Marin, IUEM, rue Dumont d'Urville, 29280 Plouzané, France. Electronic address: laure.pecquerie@ird.fr.
[Ti] Título:Is reproduction limiting growth?: Comment on "Physics of metabolic organization" by Marko Jusup et al.
[So] Source:Phys Life Rev;20:75-77, 2017 03.
[Is] ISSN:1873-1457
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Mh] Termos MeSH primário: Metabolismo Energético
Reprodução
[Mh] Termos MeSH secundário: Fenômenos Bioquímicos
Seres Humanos
Física
Fenômenos Fisiológicos
[Pt] Tipo de publicação:JOURNAL ARTICLE; COMMENT
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171026
[Lr] Data última revisão:
171026
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170204
[St] Status:MEDLINE


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[PMID]:28094149
[Au] Autor:Maino JL; Kearney MR
[Ad] Endereço:School of BioSciences, The University of Melbourne, Victoria 3010, Australia. Electronic address: jamesmaino@gmail.com.
[Ti] Título:The universality of the von Bertalanffy growth curve: Comment on: "Physics of metabolic organization" by Marko Jusup et al.
[So] Source:Phys Life Rev;20:63-65, 2017 03.
[Is] ISSN:1873-1457
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Mh] Termos MeSH primário: Física
Fenômenos Fisiológicos
[Mh] Termos MeSH secundário: Fenômenos Bioquímicos
Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE; COMMENT
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171026
[Lr] Data última revisão:
171026
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170118
[St] Status:MEDLINE


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[PMID]:28052062
[Au] Autor:Sáenz JB; Mills JC
[Ad] Endereço:Division of Gastroenterology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri 63110, USA.
[Ti] Título:Biological techniques: Stomach growth in a dish.
[So] Source:Nature;541(7636):160-161, 2017 01 12.
[Is] ISSN:1476-4687
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Fenômenos Fisiológicos
[Mh] Termos MeSH secundário: Seres Humanos
Estômago
[Pt] Tipo de publicação:NEWS; COMMENT
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170922
[Lr] Data última revisão:
170922
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170105
[St] Status:MEDLINE
[do] DOI:10.1038/nature21110


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[PMID]:27864923
[Au] Autor:Hardwick RN; Viergever C; Chen AE; Nguyen DG
[Ad] Endereço:Organovo Holdings Inc, San Diego, California, USA.
[Ti] Título:3D bioengineered tissues: From advancements in in vitro safety to new horizons in disease modeling.
[So] Source:Clin Pharmacol Ther;101(4):453-457, 2017 Apr.
[Is] ISSN:1532-6535
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Research aimed at more fully emulating human biology in vitro has rapidly progressed in recent years with advancements in 3D tissue engineering and microphysiological systems. The initial target of such systems has been directed towards drug and chemical safety assessment, with the goal of improving sensitivity and predictive capabilities. Here we discuss recent developments of in vitro organ culture systems, and their future applications in modeling human disease.
[Mh] Termos MeSH primário: Modelos Animais de Doenças
Engenharia Tecidual/tendências
[Mh] Termos MeSH secundário: Animais
Seres Humanos
Imagem Tridimensional
Fenômenos Fisiológicos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170516
[Lr] Data última revisão:
170516
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:161120
[St] Status:MEDLINE
[do] DOI:10.1002/cpt.569



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