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[PMID]:28391765
[Au] Autor:Kwiecien SY; McHugh MP; Howatson G
[Ad] Endereço:a Nicholas Institute of Sports Medicine and Athletic Trauma , Lenox Hill Hospital , New York , NY , USA.
[Ti] Título:The efficacy of cooling with phase change material for the treatment of exercise-induced muscle damage: pilot study.
[So] Source:J Sports Sci;36(4):407-413, 2018 Feb.
[Is] ISSN:1466-447X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Post-exercise cryotherapy treatments are typically short duration interventions. This study examined the efficacy of prolonged cooling using phase change material (PCM) on strength loss and pain after eccentric exercise. Eight adults performed 120 bilateral eccentric quadriceps contractions (90% MVC). Immediately afterwards, frozen PCM packs (15°C) were placed over the quadriceps, with room temperature PCM packs on the contralateral quadriceps. Skin temperature was recorded continually (6 h PCM application). Isometric quadriceps strength and soreness were assessed before, 24, 48, 72 and 96 h post-exercise. The protocol was repeated 5 months later, with room temperature PCM applied to both legs. There were three treatments: legs treated with 15°C PCM packs (direct cooling), legs treated with room temperature PCM packs contralateral to the 15°C PCM packs (systemic cooling), and legs tested 5 months later both treated with room temperature PCM packs (control). Skin temperature was 9°C-10°C lower with direct cooling versus systemic cooling and control (P < 0.01). Strength loss and soreness were less (P < 0.05) with direct cooling versus systemic cooling and control (strength 101%, 94%, 93%, respectively; pain 1.0, 2.3, 2.7, respectively). Six hours of PCM cooling was well tolerated and reduced strength loss and pain after damaging exercise.
[Mh] Termos MeSH primário: Crioterapia/métodos
Exercício/fisiologia
Força Muscular/fisiologia
Mialgia/prevenção & controle
Músculo Quadríceps/lesões
Músculo Quadríceps/fisiologia
[Mh] Termos MeSH secundário: Adulto
Feminino
Seres Humanos
Masculino
Projetos Piloto
Recuperação de Função Fisiológica
Temperatura Cutânea
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180302
[Lr] Data última revisão:
180302
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170411
[St] Status:MEDLINE
[do] DOI:10.1080/02640414.2017.1312492


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[PMID]:29357373
[Au] Autor:Maley MJ; Minett GM; Bach AJE; Zietek SA; Stewart KL; Stewart IB
[Ad] Endereço:Institute of Health and Biomedical Innovation, School of Exercise and Nutrition Sciences, Queensland University of Technology, Brisbane, Australia.
[Ti] Título:Internal and external cooling methods and their effect on body temperature, thermal perception and dexterity.
[So] Source:PLoS One;13(1):e0191416, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: The present study aimed to compare a range of cooling methods possibly utilised by occupational workers, focusing on their effect on body temperature, perception and manual dexterity. METHODS: Ten male participants completed eight trials involving 30 min of seated rest followed by 30 min of cooling or control of no cooling (CON) (34°C, 58% relative humidity). The cooling methods utilised were: ice cooling vest (CV0), phase change cooling vest melting at 14°C (CV14), evaporative cooling vest (CVEV), arm immersion in 10°C water (AI), portable water-perfused suit (WPS), heliox inhalation (HE) and ice slushy ingestion (SL). Immediately before and after cooling, participants were assessed for fine (Purdue pegboard task) and gross (grip and pinch strength) manual dexterity. Rectal and skin temperature, as well as thermal sensation and comfort, were monitored throughout. RESULTS: Compared with CON, SL was the only method to reduce rectal temperature (P = 0.012). All externally applied cooling methods reduced skin temperature (P<0.05), though CV0 resulted in the lowest skin temperature versus other cooling methods. Participants felt cooler with CV0, CV14, WPS, AI and SL (P<0.05). AI significantly impaired Purdue pegboard performance (P = 0.001), but did not affect grip or pinch strength (P>0.05). CONCLUSION: The present study observed that ice ingestion or ice applied to the skin produced the greatest effect on rectal and skin temperature, respectively. AI should not be utilised if workers require subsequent fine manual dexterity. These results will help inform future studies investigating appropriate pre-cooling methods for the occupational worker.
[Mh] Termos MeSH primário: Temperatura Corporal
Gelo
Sensação Térmica
[Mh] Termos MeSH secundário: Adulto
Feminino
Seres Humanos
Masculino
Temperatura Cutânea
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T; RESEARCH SUPPORT, U.S. GOV'T, NON-P.H.S.
[Nm] Nome de substância:
0 (Ice)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180226
[Lr] Data última revisão:
180226
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180123
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0191416


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[PMID]:29338262
[Au] Autor:Ashigai H; Taniguchi Y; Matsukura Y; Ikeshima E; Nakashima K; Mizutani M; Yajima H
[Ad] Endereço:Research Laboratories for Health Science & Food Technologies, Kirin Co., Ltd. , 1-17-5 Namamugi, Tsurumi-ku, Yokohama 230-8628, Japan.
[Ti] Título:Roasted Barley Extract Affects Blood Flow in the Rat Tail and Increases Cutaneous Blood Flow and Skin Temperature in Humans.
[So] Source:J Agric Food Chem;66(5):1251-1257, 2018 Feb 07.
[Is] ISSN:1520-5118
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Roasted barley extract (RBE, "Mugicha") is a traditional Japanese beverage reported to improve blood viscosity and affect food functionality. RBE is suggested to contain 2,5-diketopiperazines, which are the functional component with neuroprotective and immunostimulatory effects that are produced in food through roasting. In this study, we investigated the effects of RBE on blood circulation, both clinically and in rats. At first, we confirmed five 2,5-diketopiperazine derivatives in RBE by LC-MS analysis. Secondarily, we revealed that RBE affects blood flow in the rat tail and compared the efficacy on rat tail blood flow among five 2,5-diketopiperazines in RBE. Especially, cyclo(d-Phe-l-Pro) was the most effective in increasing blood flow in the rat tail. We also researched the mechanism of cyclo(d-Phe-l-Pro) with rat aorta study. As a result, we confirmed that cyclo(d-Phe-l-Pro) has an effect on vasodilatation through the release of nitric oxide in the vascular endothelium. Finally, we also confirmed that RBE affects cutaneous blood flow and increases skin temperature in humans.
[Mh] Termos MeSH primário: Hordeum/química
Temperatura Alta
Extratos Vegetais/farmacologia
Temperatura Cutânea/efeitos dos fármacos
Pele/irrigação sanguínea
Cauda/irrigação sanguínea
[Mh] Termos MeSH secundário: Adulto
Animais
Velocidade do Fluxo Sanguíneo/efeitos dos fármacos
Dicetopiperazinas/análise
Dicetopiperazinas/farmacologia
Método Duplo-Cego
Feminino
Manipulação de Alimentos/métodos
Seres Humanos
Japão
Fluxometria por Laser-Doppler
Masculino
Placebos
Ratos
Ratos Wistar
Organismos Livres de Patógenos Específicos
Vasodilatação/efeitos dos fármacos
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Diketopiperazines); 0 (Placebos); 0 (Plant Extracts); 240L69DTV7 (2,5-dioxopiperazine)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180226
[Lr] Data última revisão:
180226
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180118
[St] Status:MEDLINE
[do] DOI:10.1021/acs.jafc.7b04930


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[PMID]:27167826
[Au] Autor:Okamoto-Mizuno K; Mizuno K; Shirakawa S
[Ad] Endereço:a Kansei Fukushi Research Center , Tohoku Fukushi University , Miyagi , Japan.
[Ti] Título:Sleep and Skin Temperature in Preschool Children and Their Mothers.
[So] Source:Behav Sleep Med;16(1):64-78, 2018 Jan-Feb.
[Is] ISSN:1540-2010
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The purpose of this study was to investigate and compare sleep and skin temperature (Tsk) of preschool children with those of their mothers. The subjects included 18 pairs of preschool children and their mothers. The actigraphic measurement of sleep, Tsk, heart rate, bedroom climate, and the microclimate temperature and humidity (bed climate) were measured. Proximal and distal Tsk, the temperature gradient of distal and proximal Tsk (DPG), and bed climate temperature were significantly lower in the children. Approximately 70% of the children slept without bed covering. Heat dissipation during sleep in preschool children may primarily rely on the proximal Tsk. The lower Tsk than adults, and behavioral thermoregulation, may be important for sleep in preschoolers.
[Mh] Termos MeSH primário: Mães
Temperatura Cutânea
Sono/fisiologia
[Mh] Termos MeSH secundário: Actigrafia
Adulto
Regulação da Temperatura Corporal/fisiologia
Pré-Escolar
Feminino
Frequência Cardíaca
Seres Humanos
Umidade
Masculino
Temperatura Ambiente
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1712
[Cu] Atualização por classe:180216
[Lr] Data última revisão:
180216
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160512
[St] Status:MEDLINE
[do] DOI:10.1080/15402002.2016.1173552


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[PMID]:28452865
[Au] Autor:Meade RD; Kenny GP
[Ad] Endereço:Human and Environmental Physiology Research Unit, School of Human Kinetics, University of Ottawa, Montpetit Hall, Ottawa, CANADA.
[Ti] Título:Are All Heat Loads Created Equal?
[So] Source:Med Sci Sports Exerc;49(9):1796-1804, 2017 Sep.
[Is] ISSN:1530-0315
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PURPOSE: We evaluated physiological responses during exercise at a fixed evaporative requirement for heat balance (Ereq) but varying combinations of metabolic and environmental heat load. METHODS: Nine healthy, physically active males (age: 46 ± 8 yr) performed four experimental sessions consisting of 75 min of semirecumbent cycling at various ambient temperatures. Whole-body dry heat loss (direct calorimetry) was monitored continuously as was heat production (indirect calorimetry), which was adjusted to achieve an Ereq of 400 W. The resultant metabolic heat productions and ambient temperatures for the sessions were as follows: (i) 440 W and 30°C (440 [30]), (ii) 388 W and 35°C (388 [35]), (iii) 317 W and 40°C (317 [40]), and (iv) 258 W and 45°C (258 [45]). Whole-body evaporative heat loss was determined via direct calorimetry. Esophageal (Tes) and mean skin (Tsk) temperatures as well as HR were monitored continuously. Mean body temperature (Tb) was calculated from Tes and Tsk. Physiological strain index (PSI) was determined from Tes and HR. RESULTS: End-exercise evaporative heat loss and Tb were similar between conditions (both P ≥ 0.48). Tes was greater in 440 [30] (37.67°C ± 0.04°C) and 388 [35] (37.58°C ± 0.07°C) relative to both 317 [40] (37.35°C ± 0.06°C) and 258 [45] (37.20°C ± 0.07°C; all P ≤ 0.05). Further, Tsk was different between each condition (440 [30], 33.85°C ± 0.16°C; 388 [35], 34.53°C ± 0.08°C; 317 [40], 35.67°C ± 0.07°C; and 258 [45], 36.54°C ± 0.08°C; all P < 0.01). In 440 [30], HR was elevated by about 13 and 18 bpm relative to 317 [40] and 258 [45], respectively (both P < 0.01). Finally, PSI was greater in both 440 [30] and 388 [35] compared with 317 [40] and 258 [45] (all P ≤ 0.04). CONCLUSIONS: Exercise at a fixed Ereq resulted in similar evaporative heat loss and Tb. However, the Tes, Tsk, HR, and PSI responses varied depending on the relative contribution of metabolic and environmental heat load.
[Mh] Termos MeSH primário: Exercício/fisiologia
Temperatura Alta
Sudorese/fisiologia
[Mh] Termos MeSH secundário: Adulto
Temperatura Corporal/fisiologia
Calorimetria
Calorimetria Indireta
Esôfago/fisiologia
Frequência Cardíaca/fisiologia
Seres Humanos
Masculino
Meia-Idade
Temperatura Cutânea/fisiologia
Termometria/métodos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180108
[Lr] Data última revisão:
180108
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170429
[St] Status:MEDLINE
[do] DOI:10.1249/MSS.0000000000001309


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[PMID]:28467200
[Au] Autor:Santesson P; Lins PE; Kalani M; Adamson U; Lelic I; von Wendt G; Fagrell B; Jörneskog G
[Ad] Endereço:1 Microcirculatory Laboratory, Division of Medicine, Department of Clinical Sciences, Karolinska Institutet, Danderyd Hospital, Stockholm, Sweden.
[Ti] Título:Skin microvascular function in patients with type 1 diabetes: An observational study from the onset of diabetes.
[So] Source:Diab Vasc Dis Res;14(3):191-199, 2017 May.
[Is] ISSN:1752-8984
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The development of disturbances in skin microcirculation in type 1 diabetes is not well characterised. We assessed skin microcirculation longitudinally from the onset of diabetes up to 29 years of duration to investigate when such disturbances start. MATERIAL AND METHODS: Seventeen adult patients with type 1 diabetes participated. Skin microvascular function in digit IV of the left hand was investigated by laser Doppler fluxmetry (LDF, arbitrary units [AU]). LDF was carried out at rest and following one-min arterial occlusion. Time to peak LDF (s) and percentage increase of LDF (post-occlusive reactive hyperaemia, PRH%) were determined. Retinopathy was assessed from fundus photographs or ophthalmoscopic recordings. RESULTS: Skin microvascular function remained normal during the first five years. Compared with baseline and a non-diabetic reference group, time to peak LDF was prolonged after 7-9 years of diabetes ( p < 0.01). PRH% was lower than in the reference group after 7-9 years ( p < 0.01), and lower than baseline after 24-29 years of diabetes ( p < 0.05). All but one patient developed retinopathy and the first signs were found after 10 years of diabetes. CONCLUSIONS: Functional disturbances in total skin microcirculation were observed after seven years in patients with type 1 diabetes and preceded diabetic complications such as retinopathy.
[Mh] Termos MeSH primário: Diabetes Mellitus Tipo 1/complicações
Angiopatias Diabéticas/etiologia
Microcirculação
Microvasos/fisiopatologia
Pele/irrigação sanguínea
[Mh] Termos MeSH secundário: Adulto
Velocidade do Fluxo Sanguíneo
Estudos de Casos e Controles
Diabetes Mellitus Tipo 1/diagnóstico
Diabetes Mellitus Tipo 1/fisiopatologia
Angiopatias Diabéticas/diagnóstico
Angiopatias Diabéticas/fisiopatologia
Neuropatias Diabéticas/diagnóstico
Neuropatias Diabéticas/etiologia
Retinopatia Diabética/diagnóstico
Retinopatia Diabética/etiologia
Progressão da Doença
Feminino
Seres Humanos
Fluxometria por Laser-Doppler
Estudos Longitudinais
Masculino
Meia-Idade
Oftalmoscopia
Estudos Prospectivos
Fluxo Sanguíneo Regional
Fatores de Risco
Temperatura Cutânea
Fatores de Tempo
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; OBSERVATIONAL STUDY
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171219
[Lr] Data última revisão:
171219
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170504
[St] Status:MEDLINE
[do] DOI:10.1177/1479164117694463


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[PMID]:28922392
[Au] Autor:Kosonogov V; De Zorzi L; Honoré J; Martínez-Velázquez ES; Nandrino JL; Martinez-Selva JM; Sequeira H
[Ad] Endereço:School of Psychology, University of Murcia, Murcia, Spain.
[Ti] Título:Facial thermal variations: A new marker of emotional arousal.
[So] Source:PLoS One;12(9):e0183592, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Functional infrared thermal imaging (fITI) is considered a promising method to measure emotional autonomic responses through facial cutaneous thermal variations. However, the facial thermal response to emotions still needs to be investigated within the framework of the dimensional approach to emotions. The main aim of this study was to assess how the facial thermal variations index the emotional arousal and valence dimensions of visual stimuli. Twenty-four participants were presented with three groups of standardized emotional pictures (unpleasant, neutral and pleasant) from the International Affective Picture System. Facial temperature was recorded at the nose tip, an important region of interest for facial thermal variations, and compared to electrodermal responses, a robust index of emotional arousal. Both types of responses were also compared to subjective ratings of pictures. An emotional arousal effect was found on the amplitude and latency of thermal responses and on the amplitude and frequency of electrodermal responses. The participants showed greater thermal and dermal responses to emotional than to neutral pictures with no difference between pleasant and unpleasant ones. Thermal responses correlated and the dermal ones tended to correlate with subjective ratings. Finally, in the emotional conditions compared to the neutral one, the frequency of simultaneous thermal and dermal responses increased while both thermal or dermal isolated responses decreased. Overall, this study brings convergent arguments to consider fITI as a promising method reflecting the arousal dimension of emotional stimulation and, consequently, as a credible alternative to the classical recording of electrodermal activity. The present research provides an original way to unveil autonomic implication in emotional processes and opens new perspectives to measure them in touchless conditions.
[Mh] Termos MeSH primário: Nível de Alerta/fisiologia
Emoções/fisiologia
Face/fisiologia
Imagem Tridimensional
Temperatura Cutânea/fisiologia
[Mh] Termos MeSH secundário: Adulto
Feminino
Seres Humanos
Masculino
[Pt] Tipo de publicação:CLINICAL TRIAL; JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171016
[Lr] Data última revisão:
171016
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170919
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0183592


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[PMID]:28704150
[Au] Autor:Power G; Moore Z; O'Connor T
[Ad] Endereço:Community Registered General Nurse, HSE Carlow/Kilkenny, Ireland.
[Ti] Título:Measurement of pH, exudate composition and temperature in wound healing: a systematic review.
[So] Source:J Wound Care;26(7):381-397, 2017 Jul 02.
[Is] ISSN:0969-0700
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To assess the potential of measurements of pH, exudate composition and temperature in wounds to predict healing outcomes and to identify the methods that are employed to measure them. METHOD: A systematic review based on the outcomes of a search strategy of quantitative primary research published in the English language was conducted. Inclusion criteria limited studies to those involving in vivo and human participants with an existing or intentionally provoked wound, defined as 'a break in the epithelial integrity of the skin', and excluded in vitro and animal studies. Data synthesis and analysis was performed using structured narrative summaries of each included study arranged by concept, pH, exudate composition and temperature. The Evidence Based Literature (EBL) Critical Appraisal Checklist was implemented to appraise the quality of the included studies. RESULTS: A total of 23 studies, three for pH (mean quality score 54.48%), 12 for exudate composition (mean quality score 46.54%) and eight for temperature (mean quality score 36.66%), were assessed as eligible for inclusion in this review. Findings suggest that reduced pH levels in wounds, from alkaline towards acidic, are associated with improvements in wound condition. Metalloproteinase-9 (MMP-9), matrix metalloproteinase-2 (MMP-2), tissue inhibitor of metalloproteinase (TIMP), neutrophil elastase (NE) and albumin, in descending order, were the most frequently measured analytes in wounds. MMP-9 emerged as the analyte which offers the most potential as a biomarker of wound healing, with elevated levels observed in acute or non-healing wounds and decreasing levels in wounds progressing in healing. Combined measures of different exudate components, such as MMP/TIMP ratios, also appeared to offer substantial potential to indicate wound healing. Finally, temperature measurements are highest in non-healing, worsening or acute wounds and decrease as wounds progress towards healing. Methods used to measure pH, exudate composition and temperature varied greatly and, despite noting some similarities, the studies often yielded significantly contrasting results. Furthermore, a limitation to the generalisability of the findings was the overall quality scores of the research studies, which appeared suboptimal. CONCLUSION: Despite some promising findings, there was insufficient evidence to confidently recommend the use of any of these measures as predictors of wound healing. pH measurement appeared as the most practical method for use in clinical practice to indicate wound healing outcomes. Further research is required to increase the strength of evidence and develop a greater understanding of wound healing dynamics.
[Mh] Termos MeSH primário: Biomarcadores/metabolismo
Exsudatos e Transudatos/metabolismo
Temperatura Cutânea
Cicatrização
Ferimentos e Lesões
[Mh] Termos MeSH secundário: Albuminas/metabolismo
Exsudatos e Transudatos/química
Seres Humanos
Concentração de Íons de Hidrogênio
Elastase de Leucócito/metabolismo
Metaloproteinase 2 da Matriz/metabolismo
Metaloproteinase 9 da Matriz/metabolismo
Temperatura Ambiente
Inibidores Teciduais de Metaloproteinases/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Albumins); 0 (Biomarkers); 0 (Tissue Inhibitor of Metalloproteinases); EC 3.4.21.37 (Leukocyte Elastase); EC 3.4.24.24 (MMP2 protein, human); EC 3.4.24.24 (Matrix Metalloproteinase 2); EC 3.4.24.35 (MMP9 protein, human); EC 3.4.24.35 (Matrix Metalloproteinase 9)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170926
[Lr] Data última revisão:
170926
[Sb] Subgrupo de revista:N
[Da] Data de entrada para processamento:170714
[St] Status:MEDLINE
[do] DOI:10.12968/jowc.2017.26.7.381


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[PMID]:28701321
[Au] Autor:Barrett KT; Daubenspeck JA; Wilson RJA
[Ad] Endereço:Department of Physiology and Pharmacology, Hotchkiss Brain Institute and Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada; and.
[Ti] Título:Pituitary adenylate cyclase-activating polypeptide drives cardiorespiratory responses to heat stress in neonatal mice.
[So] Source:Am J Physiol Regul Integr Comp Physiol;313(4):R385-R394, 2017 Oct 01.
[Is] ISSN:1522-1490
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP) has emerged as a principal and rate-limiting regulator of physiological stress responses in adult rodents and has been implicated in sudden infant death syndrome (SIDS). Recent studies show that PACAP plays a role in neonatal cardiorespiratory responses to hypoxia, hypercapnia, and hypothermia, but not hyperthermia, which is often associated with SIDS. Here we tested the hypothesis that, consistent with a role in SIDS, PACAP is involved in regulating the neonatal cardiorespiratory responses to severe heat. To address this, we used head-out plethysmography and surface ECG electrodes to study the cardiorespiratory physiology of conscious neonatal PACAP-null and wild-type mice at ambient temperatures of 32°C (baseline) and 40°C (heat stress). We also assessed body surface temperature as an indicator of cutaneous heat loss. Our results show that wild-type neonatal mice respond to heat stress by increasing ventilation ( = 0.007) and associated expired CO ( = 0.041), heart rate ( < 0.001), and cutaneous heat loss ( < 0.001). In PACAP-null neonates, this heat response is impaired, as indicated by a decrease in ventilation ( = 0.04) and associated expired CO ( = 0.006) and a blunted increase in heart rate ( = 0.001) and cutaneous heat loss ( = 0.0002). In addition, heart rate variability at baseline was lower in PACAP-null neonates than wild-type controls ( < 0.01). These results suggest that, during heat stress, PACAP is important for neonatal cardiorespiratory responses that help regulate body temperature. Abnormal PACAP regulation could, therefore, contribute to neonatal disorders in which the autonomic response to stress is impaired, such as SIDS.
[Mh] Termos MeSH primário: Regulação da Temperatura Corporal/fisiologia
Aptidão Cardiorrespiratória/fisiologia
Frequência Cardíaca/fisiologia
Resposta ao Choque Térmico/fisiologia
Polipeptídeo Hipofisário Ativador de Adenilato Ciclase/metabolismo
[Mh] Termos MeSH secundário: Animais
Animais Recém-Nascidos
Ativação Enzimática
Feminino
Masculino
Camundongos
Camundongos Knockout
Fatores Sexuais
Temperatura Cutânea/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Pituitary Adenylate Cyclase-Activating Polypeptide)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171006
[Lr] Data última revisão:
171006
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170714
[St] Status:MEDLINE
[do] DOI:10.1152/ajpregu.00118.2017


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[PMID]:28691581
[Au] Autor:Whitworth-Turner C; Di Michele R; Muir I; Gregson W; Drust B
[Ad] Endereço:a Football Exchange, Research Institute for Sport and Exercise Sciences , Liverpool John Moores University , Liverpool , UK.
[Ti] Título:A shower before bedtime may improve the sleep onset latency of youth soccer players.
[So] Source:Eur J Sport Sci;17(9):1119-1128, 2017 Oct.
[Is] ISSN:1536-7290
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:During the competitive season, soccer players are likely exposed to numerous factors that may disrupt the process of sleep. The current investigation looked to evaluate a practical sleep hygiene strategy (10-min showering at ∼40°C before lights out), within a group of 11 youth soccer players in comparison to normal sleeping conditions (control). Each condition consisted of three days within a randomised crossover trial design. Sleep information was collected using a commercial wireless bedside sleep monitor. Measures of skin temperature were evaluated using iButton skin thermistors to establish both distal and proximal skin temperatures and distal to proximal gradient. The shower intervention elevated distal skin temperature by 1.1°C (95% CI: 0.1-2.1°C, p = .04) on average prior to lights out. The elevation in distal temperature was also present during the first 30-min following lights out (1.0°C, 95% CI: 0.4-1.6°C, p < .01). The distal to proximal gradient also showed a significant effect between the conditions within the first 30-min after lights out (0.7°C, 95% CI: 0.3-1.2°C, p < .01). On average the sleep latency of the youth soccer players was -7-min lower (95% CI: -13 to -2 min, p < .01) and sleep efficiency +2% higher (95% CI: 1-3%; p < .01) in the shower condition. These findings demonstrate that a warm shower performed before lights out may offer a practical strategy to promote thermoregulatory changes that may advance sleep onset latency and improve sleep efficiency in athletes.
[Mh] Termos MeSH primário: Banhos
Higiene do Sono
Sono/fisiologia
Futebol
[Mh] Termos MeSH secundário: Adolescente
Atletas
Estudos Cross-Over
Seres Humanos
Masculino
Polissonografia
Temperatura Cutânea
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171002
[Lr] Data última revisão:
171002
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170711
[St] Status:MEDLINE
[do] DOI:10.1080/17461391.2017.1346147



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