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[PMID]:29424210
[Au] Autor:Dotsenko VA; Kononenko IA; Mosiychuk LV; Argunova EV; Dolotov SA; Sirotkin OG
[Ti] Título:[Features of consumption of vitamins and foods enriched with biologically active substances by Petersburgers].
[So] Source:Gig Sanit;95(5):479-83, 2016.
[Is] ISSN:0016-9900
[Cp] País de publicação:Russia (Federation)
[La] Idioma:rus
[Ab] Resumo:Purpose. To study and evaluate the use of vitamins and products enriched with biologically active substances by the residents of St. Petersburg. The study was conducted with the use of the questionnaire survey method of 1200 Petersburgers. Results. A third of residents (35.5 per cent) never used enriched food products in nutrition. The majority of St. Petersburgers (59.3%) when cooking do not use iodized salt or do it rarely. While the use of salt increases with the age. Inclusion of vitamins in the diet fails to be widely distributed among the citizens: monthly they are used by only 20.3% of citizen, 2 times a year - 28.2% and only during illness - 17.7%. One third of the population (33.8 percent) never takes vitamins in the form of tablets, syrups, solutions, etc. Conclusion. The analysis indicates the need to improve the nutrition of Petersburgers to reduce risk factors for diseases by improving health literacy in organized units for healthy nutrition on the base of Health Centers or clinics in St. Petersburg.
[Mh] Termos MeSH primário: Deficiências Nutricionais
Alimentos Fortificados/utilização
Valor Nutritivo
[Mh] Termos MeSH secundário: Adulto
Idoso
Deficiências Nutricionais/epidemiologia
Deficiências Nutricionais/prevenção & controle
Feminino
Seres Humanos
Masculino
Meia-Idade
Estado Nutricional
Saúde Pública/métodos
Saúde Pública/estatística & dados numéricos
Federação Russa/epidemiologia
Fatores Socioeconômicos
Inquéritos e Questionários
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180301
[Lr] Data última revisão:
180301
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180210
[St] Status:MEDLINE


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[PMID]:29370249
[Au] Autor:Stougaard M; Damm P; Frederiksen P; Jacobsen R; Heitmann BL
[Ad] Endereço:Research Unit for Dietary Studies at the Parker Institute and Department of Clinical Epidemiology, Bispebjerg og Frederiksberg Hospital, The Capital Region, Copenhagen, Denmark.
[Ti] Título:Extra vitamin D from fortification and the risk of preeclampsia: The D-tect Study.
[So] Source:PLoS One;13(1):e0191288, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The objective of the study was to examine if exposure to extra vitamin D from food fortification was associated with a decrease in the risk of preeclampsia. The study was based on a natural experiment exploring the effect of the abolition of the Danish mandatory vitamin D fortification of margarine in 1985. The effect of the extra vitamin D (1.25µg vitamin D/100 g margarine) was examined by comparing preeclampsia risk in women who have been exposed or unexposed to extra vitamin D from the fortified margarine during pregnancy, and who gave birth in the period from June 1983 to August 1988. The Danish National Patient Registry allowed the identification of pregnancies complicated by preeclampsia. The study included 73,237 women who gave birth during 1983-1988. We found no association between exposure to vitamin D fortification during pregnancy and the risk of any of the pregnancy related hypertensive disorders, including preeclampsia: Odds ratios (OR, 95%) for all hypertensive pregnancy related disorders among exposed vs. unexposed women was (OR 1.04, 95%CI: 0.98,1.10). In conclusion, the extra vitamin D from the mandatory vitamin D fortification did not influence the risk of preeclampsia.
[Mh] Termos MeSH primário: Alimentos Fortificados
Pré-Eclâmpsia/prevenção & controle
Vitamina D/farmacologia
[Mh] Termos MeSH secundário: Adulto
Relação Dose-Resposta a Droga
Feminino
Seres Humanos
Gravidez
Risco
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
1406-16-2 (Vitamin D)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180226
[Lr] Data última revisão:
180226
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180126
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0191288


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[PMID]:29381288
[Au] Autor:Kodentsova VM
[Ti] Título:[About food fortification with vitamins].
[So] Source:Vopr Pitan;85(4):87-90, 2016.
[Is] ISSN:0042-8833
[Cp] País de publicação:Russia (Federation)
[La] Idioma:rus
[Ab] Resumo:Criticism of attempts to enrich foods (mainly dairy products) with vitamins by adding mashed or concentrates of fresh berries and vegetables has been reviewed. Concept "enriched (fortified) product" has been considered. It has been shown that the addition of fruits and vegetables, which are a source of vitamin C, does not increase the content of B vitamins to a level that meets the criteria for fortified foods. The differences in the regulations concerning to the degree of enrichment of foods are discussed. Development of specific educational programs to increase knowledge about vitamins is required not only for the population but also for scientific and medical professionals. Keywords: enriched with vitamins (fortified) product, fresh berries, vegetables.
[Mh] Termos MeSH primário: Ácido Ascórbico
Alimentos Fortificados
Complexo Vitamínico B
[Mh] Termos MeSH secundário: Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
12001-76-2 (Vitamin B Complex); PQ6CK8PD0R (Ascorbic Acid)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180216
[Lr] Data última revisão:
180216
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180131
[St] Status:MEDLINE


  4 / 8570 MEDLINE  
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[PMID]:29381016
[Au] Autor:Ancheva IA
[Ti] Título:[Functional food in pregnancy].
[So] Source:Vopr Pitan;85(4):22-8, 2016.
[Is] ISSN:0042-8833
[Cp] País de publicação:Russia (Federation)
[La] Idioma:rus
[Mh] Termos MeSH primário: Alimentos Fortificados
Micronutrientes/administração & dosagem
Parto/fisiologia
Gravidez/fisiologia
Fenômenos Fisiológicos da Nutrição Pré-Natal/fisiologia
Probióticos/administração & dosagem
[Mh] Termos MeSH secundário: Feminino
Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Micronutrients)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180216
[Lr] Data última revisão:
180216
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180131
[St] Status:MEDLINE


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[PMID]:29376307
[Au] Autor:Nilova LP; Pilipenko TV
[Ti] Título:[Evaluation of antioxidant properties of enriched bakery products in experiment on laboratory animals].
[So] Source:Vopr Pitan;85(6):39-47, 2016.
[Is] ISSN:0042-8833
[Cp] País de publicação:Russia (Federation)
[La] Idioma:rus
[Ab] Resumo:The purpose was to study the effect of enriched bakery products in the diet of rats on indicators of prooxidant-antioxidant system of blood serum. Experiment was carried out on male Wistar rats with initial weight 140-180 g. After a quarantine during the preparatory period rats for 14 days were accustomed to the partial (50%) replacement of the standard diet by bakery products with standard compound­ing. Then, 7 groups of rats were formed: the 1st group of rats (control group, n=10) continued to receive bakery products of a standard composition; groups with the 2nd on 7th (experimental, n=8 in everyone) received enriched bakery products: the 2nd group - with blueberry powder; the 3rd group - with mountain ash powder; the 4th group - with sea-buckthorn powder; the 5th group - with flour of a pine nut; the 6th group - with rice bran oil; the 7th group - with pumpkin oil. The intensity of free radical oxidation and antioxidant activity (by chemiluminescence method), activity of superoxide dismutase and level of secondary oxidation products reacted with thiobarbituric acid (by spectrophotometry) were monitored in rat blood serum. It has been shown that the use of bakery products with different compounding in the animal diet had different effects on indicators of prooxidant-antioxidant system of blood serum. Bakery products containing sea buckthorn pomace powder, flour of pine nut and rice bran oil reduced intensity of free radical oxidation in rat blood serum by 36.0, 24.6 and 18.8%, respectively. It is suggested that bakery products containing flour of pine nut products brake a free radical oxidation in rat blood serum in case of simultaneous content of natural antioxidants and melanoidins. The anthocyanins of powder from blueberry berries can render antioxidant effect and slow down formation of by-products of oxidation. No statistically significant change on indicators of prooxidant-antioxidant system of blood serum of rats treated with bakery products with rowan powder or pumpkin oil was found, that may be due to animal refusal to eat such products.
[Mh] Termos MeSH primário: Antioxidantes/metabolismo
Pão
Alimentos Fortificados
Radicais Livres/sangue
[Mh] Termos MeSH secundário: Animais
Masculino
Ratos
Ratos Wistar
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antioxidants); 0 (Free Radicals)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180216
[Lr] Data última revisão:
180216
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180130
[St] Status:MEDLINE


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[PMID]:29327584
[Au] Autor:Si X; Shang W; Zhou Z; Shui G; Lam SM; Blanchard C; Strappe P
[Ad] Endereço:Key Laboratory of Food Nutrition and Safety, Ministry of Education, Tianjin University of Science and Technology , Tianjin 300457, China.
[Ti] Título:Gamma-aminobutyric Acid Enriched Rice Bran Diet Attenuates Insulin Resistance and Balances Energy Expenditure via Modification of Gut Microbiota and Short-Chain Fatty Acids.
[So] Source:J Agric Food Chem;66(4):881-890, 2018 Jan 31.
[Is] ISSN:1520-5118
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:In this study, gamma-aminobutyric acid (GABA) enriched rice bran (ERB) was supplemented to obese rats to investigate the attenuation of metabolic syndromes induced by high-fat diet. ERB-containing diet stimulated butyrate and propionate production by promoting Anaerostipes, Anaerostipes sp., and associated synthesizing enzymes. This altered short-chain fatty acid (SCFA) distribution further enhanced circulatory levels of leptin and glucagon-like peptide-1, controlling food intake by downregulating orexigenic factors. Together with the enhanced fatty acid ß-oxidation highlighted by Prkaa2, Ppara, and Scd1 expression via AMPK signaling pathway and nonalcoholic fatty liver disease pathway, energy expenditure was positively modulated. Serum lipid compositions showed ERB supplement exhibited a more efficient effect on lowering serum sphingolipids, which was closely associated with the status of insulin resistance. Consistently, genes of Ppp2r3b and Prkcg, involved in the function of ceramides in blocking insulin action, were also downregulated following ERB intervention. Enriched GABA and phenolic acids were supposed to be responsible for the health-beneficial effects.
[Mh] Termos MeSH primário: Metabolismo Energético/efeitos dos fármacos
Alimentos Fortificados
Microbioma Gastrointestinal/efeitos dos fármacos
Resistência à Insulina
Oryza
Ácido gama-Aminobutírico/administração & dosagem
[Mh] Termos MeSH secundário: Tecido Adiposo/metabolismo
Animais
Ceramidas/fisiologia
DNA/análise
Dieta
Dieta Hiperlipídica
Ácidos Graxos Voláteis/sangue
Microbioma Gastrointestinal/fisiologia
Peptídeo 1 Semelhante ao Glucagon/sangue
Leptina/sangue
Fígado/metabolismo
Masculino
Síndrome Metabólica/etiologia
Síndrome Metabólica/prevenção & controle
Obesidade/terapia
Ratos
Ratos Sprague-Dawley
Sementes
Esfingolipídeos/sangue
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Ceramides); 0 (Fatty Acids, Volatile); 0 (Leptin); 0 (Sphingolipids); 56-12-2 (gamma-Aminobutyric Acid); 89750-14-1 (Glucagon-Like Peptide 1); 9007-49-2 (DNA)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180212
[Lr] Data última revisão:
180212
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180113
[St] Status:MEDLINE
[do] DOI:10.1021/acs.jafc.7b04994


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[PMID]:28746725
[Au] Autor:Duizer LM; Diana A; Rathomi HS; Luftimas DE; Rahmannia S; Santi W; Nugraha GI; Haszard JJ; Gibson RS; Houghton LA
[Ad] Endereço:Dept. of Food Science, Univ. of Guelph, Canada, N1G 2W1.
[Ti] Título:An Acceptability Trial of Desiccated Beef Liver and Meat Powder as Potential Fortifiers of Complementary Diets of Young Children in Indonesia.
[So] Source:J Food Sci;82(9):2206-2212, 2017 Sep.
[Is] ISSN:1750-3841
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The addition of desiccated beef liver to infant and young child complementary foods can be used to overcome nutrient deficits, however its acceptability is unknown. We conducted a series of studies to test the acceptability of complementary foods fortified with either powdered beef liver, beef meat, beef liver + meat or placebo among 96 Indonesian children aged 12 to 23 mo. This was achieved by determining liking of a single test food with added study powder, followed by a 2-wk home trial and focus group discussions to assess liking during repeated consumption of the study powders added to daily meals. The test food with added beef powders were well liked by mothers, with liking scores never falling below neutral on a 7-point scale. After home use, mothers reported that their children moderately liked their meals with added powder, with scores ranging between 3.3 and 3.5 on a 5-point scale. With the exception of lower liking for the combination beef liver + meat powder, there were no detectable differences in mothers' overall perception of child's liking between the placebo and any of the study powders. The low disappearance rate of the study powders during the home trial was a concern, with mothers reporting a strong smell and fishy odor as the major reason why children did not like their meals. Nonetheless, mothers declared they would continue using the powder on account of the nutritional value and perceived health benefits. Strategies are underway to minimize the level of fishy odor in the beef liver powder.
[Mh] Termos MeSH primário: Comportamento do Consumidor
Alimentos Fortificados/análise
Alimentos Infantis/análise
Fígado/química
Carne/análise
[Mh] Termos MeSH secundário: Animais
Bovinos
Feminino
Seres Humanos
Indonésia
Lactente
Fígado/metabolismo
Masculino
Valor Nutritivo
Pós/química
[Pt] Tipo de publicação:CLINICAL TRIAL, PHASE I; CLINICAL TRIAL, PHASE II; JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Powders)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180212
[Lr] Data última revisão:
180212
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170727
[St] Status:MEDLINE
[do] DOI:10.1111/1750-3841.13807


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[PMID]:29353552
[Au] Autor:Verhoef H; Teshome E; Prentice AM
[Ad] Endereço:MRC Unit The Gambia, Atlantic Boulevard, Fajara, Gambia. hans.verhoef@icloud.com.
[Ti] Título:Micronutrient powders to combat anaemia in young children: do they work?
[So] Source:BMC Med;16(1):7, 2018 01 22.
[Is] ISSN:1741-7015
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:In 2016, the World Health Organization (WHO) recommended point-of-use fortification of complementary foods with iron-containing micronutrient powders to improve iron status and reduce anaemia in children at risk of anaemia. This recommendation continues to be debated. In a recent trial among Kenyan children aged 12-36 months, we found no evidence that daily point-of-use fortification was efficacious in improving haemoglobin concentration or plasma iron markers. An updated meta-analysis indicated that, on average, in an arbitrarily selected setting and with adherence as obtained under trial conditions, one may expect a small increase in haemoglobin concentration in preschool children, with the upper limit of the 95% CI virtually excluding an effect beyond 5.5 g/L. In the present paper, we elaborate on the interpretation of these findings and the meta-analyses that formed the basis for the WHO guidelines. In particular, we draw attention to the phenomenon that small group differences in the distribution of continuous outcomes (haemoglobin concentration, ferritin concentrations) can give a false impression of relatively large effects on the prevalence of the dichotomised outcomes (anaemia, iron deficiency).Please see related articles: https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-017-0839-z , https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-017-0867-8.
[Mh] Termos MeSH primário: Anemia Ferropriva/sangue
Micronutrientes/deficiência
[Mh] Termos MeSH secundário: Anemia/sangue
Suplementos Nutricionais
Alimentos Fortificados
Hemoglobinas
Seres Humanos
Quênia/epidemiologia
Pós
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T; COMMENT
[Nm] Nome de substância:
0 (Hemoglobins); 0 (Micronutrients); 0 (Powders)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180201
[Lr] Data última revisão:
180201
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180123
[St] Status:MEDLINE
[do] DOI:10.1186/s12916-017-0998-y


  9 / 8570 MEDLINE  
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[PMID]:28449690
[Au] Autor:Teshome EM; Andang'o PEA; Osoti V; Terwel SR; Otieno W; Demir AY; Prentice AM; Verhoef H
[Ad] Endereço:MRCG Keneba at MRC Unit, Banjul, The Gambia. Emily.teshome@lshtm.ac.uk.
[Ti] Título:Daily home fortification with iron as ferrous fumarate versus NaFeEDTA: a randomised, placebo-controlled, non-inferiority trial in Kenyan children.
[So] Source:BMC Med;15(1):89, 2017 04 28.
[Is] ISSN:1741-7015
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: We aimed to show the non-inferiority of home fortification with a daily dose of 3 mg iron in the form of iron as ferric sodium ethylenediaminetetraacetate (NaFeEDTA) compared with 12.5 mg iron as encapsulated ferrous fumarate in Kenyan children aged 12-36 months. In addition, we updated a recent meta-analysis to assess the efficacy of home fortification with iron-containing powders, with a view to examining diversity in trial results. METHODS: We gave chemoprevention by dihydroartemisinin-piperaquine, albendazole and praziquantel to 338 afebrile children with haemoglobin concentration ≥70 g/L. We randomly allocated them to daily home fortification for 30 days with either placebo, 3 mg iron as NaFeEDTA or 12.5 mg iron as encapsulated ferrous fumarate. We assessed haemoglobin concentration (primary outcome), plasma iron markers, plasma inflammation markers and Plasmodium infection in samples collected at baseline and after 30 days of intervention. We conducted a meta-analysis of randomised controlled trials in pre-school children to assess the effect of home fortification with iron-containing powders on anaemia and haemoglobin concentration at end of intervention. RESULTS: A total of 315 children completed the 30-day intervention period. At baseline, 66.9% of children had inflammation (plasma C-reactive protein concentration >5 mg/L or plasma α -acid glycoprotein concentration >1.0 g/L); in those without inflammation, 42.5% were iron deficient. There was no evidence, either in per protocol analysis or intention-to-treat analysis, that home fortification with either of the iron interventions improved haemoglobin concentration, plasma ferritin concentration, plasma transferrin receptor concentration or erythrocyte zinc protoporphyrin-haem ratio. We also found no evidence of effect modification by iron status, anaemia status and inflammation status at baseline. In the meta-analysis, the effect on haemoglobin concentration was highly heterogeneous between trials (I : 84.1%; p value for test of heterogeneity: <0.0001). CONCLUSIONS: In this population, home fortification with either 3 mg iron as NaFeEDTA or 12.5 mg iron as encapsulated ferrous fumarate was insufficiently efficacious to assess non-inferiority of 3 mg iron as NaFeEDTA compared to 12.5 mg iron as encapsulated ferrous fumarate. Our finding of heterogeneity between trial results should stimulate subgroup analysis or meta-regression to identify population-specific factors that determine efficacy. TRIAL REGISTRATION: The trial was registered with ClinicalTrials.gov ( NCT02073149 ) on 25 February 2014.
[Mh] Termos MeSH primário: Anemia Ferropriva/prevenção & controle
Compostos Férricos/uso terapêutico
Compostos Ferrosos/uso terapêutico
Alimentos Fortificados
[Mh] Termos MeSH secundário: Anemia Ferropriva/sangue
Proteína C-Reativa
Pré-Escolar
Método Duplo-Cego
Ácido Edético/uso terapêutico
Feminino
Ferritinas
Seres Humanos
Lactente
Ferro/sangue
Quênia/epidemiologia
Malária
Masculino
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Ferric Compounds); 0 (Ferrous Compounds); 9007-41-4 (C-Reactive Protein); 9007-73-2 (Ferritins); 9G34HU7RV0 (Edetic Acid); E1UOL152H7 (Iron); KJ3C78Y22Z (Fe(III)-EDTA); R5L488RY0Q (ferrous fumarate)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:180128
[Lr] Data última revisão:
180128
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170429
[Cl] Clinical Trial:ClinicalTrial
[St] Status:MEDLINE
[do] DOI:10.1186/s12916-017-0839-z


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[PMID]:28468891
[Au] Autor:Monnard A; Moretti D; Zeder C; Steingötter A; Zimmermann MB
[Ad] Endereço:Department of Health Sciences and Technology, Laboratory of Human Nutrition, ETH Zürich, Zurich, Switzerland; and.
[Ti] Título:The effect of lipids, a lipid-rich ready-to-use therapeutic food, or a phytase on iron absorption from maize-based meals fortified with micronutrient powders.
[So] Source:Am J Clin Nutr;105(6):1521-1527, 2017 Jun.
[Is] ISSN:1938-3207
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Ready-to-use-therapeutic foods (RUTFs) high in lipid, protein, and iron are used to treat malnutrition. Lipids increase gastric residence time, which could increase iron absorption, particularly from poorly soluble iron compounds and in combination with phytase. The objectives were to ) assess the effect on iron absorption of a lipid emulsion given 20 min before or together with an iron-fortified maize meal and ) assess iron absorption from a micronutrient powder (MNP) given with a nutrient-dense RUTF and/or a microbial phytase. A total of 41 women participated in 3 studies. They consumed a maize meal fortified with isotopically labeled ferrous sulfate (FeSO ; study 1) or ferric pyrophosphate (FePP; study 2). In studies 1 and 2, a lipid emulsion was given with or 20 min before the meal. In study 3, with the use of a 2 × 2 factorial design, subjects consumed a maize meal fortified with an MNP containing labeled FeSO (MNP) given with an RUTF (MNP+RUTF), with a phytase (MNP+phytase), or both (MNP+RUTF+phytase). Iron absorption was assessed by isotope incorporation in erythrocytes 14 d after the test meals. The lipid emulsion given either before or with the meal significantly increased iron absorption from FePP by 2.55-fold (95% CI: 1.48-, 4.37-fold; = 0.001) but not from FeSO There was a trend to increase iron absorption with the MNP+RUTF meal, which did not reach significance (1.21-fold; 95% CI: 0.92-, 1.61-fold; = 0.060). The addition of phytase to MNP and MNP+RUTF significantly increased iron absorption by 1.85-fold (95% CI: 1.49-, 2.29-fold; < 0.001), with no interaction between phytase and RUTF. In iron-fortified maize-based meals, the addition of lipids more than doubles iron absorption from FePP. Our results suggest the possibility of an enhancing effect on iron absorption of lipid-rich RUTFs, but more research is needed to determine this. This trial was registered at clinicaltrials.gov as NCT01991626.
[Mh] Termos MeSH primário: 6-Fitase/farmacologia
Alimentos Fortificados
Absorção Intestinal/efeitos dos fármacos
Ferro na Dieta/sangue
Ferro/sangue
Lipídeos/farmacologia
Micronutrientes/sangue
[Mh] Termos MeSH secundário: Adulto
Suplementos Nutricionais
Difosfatos/sangue
Eritrócitos/metabolismo
Feminino
Ferritinas/sangue
Seres Humanos
Refeições
Pós
Adulto Jovem
Zea mays
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Diphosphates); 0 (Iron, Dietary); 0 (Lipids); 0 (Micronutrients); 0 (Powders); 9007-73-2 (Ferritins); E1UOL152H7 (Iron); EC 3.1.3.26 (6-Phytase); QK8899250F (ferric pyrophosphate)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:180121
[Lr] Data última revisão:
180121
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170505
[Cl] Clinical Trial:ClinicalTrial
[St] Status:MEDLINE
[do] DOI:10.3945/ajcn.116.142976



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