Base de dados : MEDLINE
Pesquisa : G07.203.300.525 [Categoria DeCS]
Referências encontradas : 163 [refinar]
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  1 / 163 MEDLINE  
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[PMID]:29430882
[Au] Autor:Pivovarov YP; Milushkina OY; Tikhonova YL; Aksenova OI; Kalinovskaya MV
[Ti] Título:[Chemical pollution of baby food products in the Russian Federation].
[So] Source:Gig Sanit;95(8):707-11, 2016.
[Is] ISSN:0016-9900
[Cp] País de publicação:Russia (Federation)
[La] Idioma:rus
[Ab] Resumo:One of the main problems of nutrition of children and adolescents is to assess chemical contamination of baby food products and the establishment of the relation with the health of the child population. With the entering different chemical compounds in the body of the child there can be observed disorders of the nervous, urinary, cardiovascular system, gastrointestinal tract, as well as metabolic deteriorations, degenerative processes in parenchymal organs and bone destruction. The aim of the study was to analyze data on chemical contamination of baby food products in the Russian Federation for 2012-2014. The analysis was executed on the data of Federal Information Fund of social and hygienic monitoring of the Russian Federation. There were identified priority pollutants (toxic elements, nitrites, nitrates, nitrosamines, pesticides, hydroxymethylfurfural, mycotoxins) and risk areas (the Lipetsk region, the Krasnodar Territory, the Republic of Adygea, city of Moscow, Tatarstan, the Kabardino-Balkar Republic, the Ryazan region). There are detected contamination levels not exceeding MAC (in the dynamics of the three years offollow up, on average 22%), requiring their hygienic assessment. There were determined the baby food products containing most common occurred chemical contaminants: fruits and vegetables products, canned products, canned meat, cereals, dairy products, liquid and adapted and partially adapted milk formalas. Identified data indicate to a need for further studies of chemical substances in products for children's nutrition in order to establish the causal relationships with a various diseases and the substantiation of methodological approaches to the risk assessment of combined exposure to chemical contaminants in concentrations up to the MPC on health of children, including infants.
[Mh] Termos MeSH primário: Poluentes Ambientais
Análise de Alimentos
Alimentos Especializados
[Mh] Termos MeSH secundário: Adolescente
Criança
Fenômenos Fisiológicos da Nutrição Infantil
Poluentes Ambientais/análise
Poluentes Ambientais/normas
Análise de Alimentos/métodos
Análise de Alimentos/normas
Qualidade dos Alimentos
Alimentos Especializados/análise
Alimentos Especializados/normas
Seres Humanos
Lactente
Política Nutricional
Federação Russa
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Environmental Pollutants)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180301
[Lr] Data última revisão:
180301
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180213
[St] Status:MEDLINE


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[PMID]:29377659
[Au] Autor:Sharafetdinov KK; Plotnikova OA; Churicheva AM; Pilipenko VV; Alekseeva RI; Sentsova TB; Maltsev GY; Kochetkova AA; Vorobyova VM; Vorobyova IS
[Ti] Título:Assessment of efficacy of specialized food products with modified carbohydrate profile in patients with type 2 diabetes.
[So] Source:Vopr Pitan;85(6):103-9, 2016.
[Is] ISSN:0042-8833
[Cp] País de publicação:Russia (Federation)
[La] Idioma:rus
[Ab] Resumo:Objective - To evaluate the effect of diet therapy with the inclusion of specialized food product with a modified carbohydrate profile (fruit jelly) on glycemic and metabolic parameters in patients with type 2 diabetes mellitus. The study included 45 patients (aged 35 to 69 years) with type 2 diabetes with concomitant obesity I-III degree. The study was conducted in two stages. The first phase evaluated the effect of jelly intake on postprandial glycemia with determination of blood glucose levels on an empty stomach and 30, 60, 120 and 180 minutes after consumption of fruit jelly with maltitol, pectin and sublimated raspberry juice and traditional marmalade with fructose (control), containing 25 g of digestible carbohydrates. In the second phase the effectiveness of combination therapy during 2 weeks of the inclusion of fruit jelly with a modified carbohydrate profile in a standard hypocaloric diet (1550 kcal/day) has been assessed. It has been shown that the dynamics of postprandial glycemia in patients with type 2 diabetes after the consumption of fruit jelly with a modified carbohydrate profile was comparable to the dynamics of blood glucose after eating traditional marmalade with fructose. Inclusion of fruit jelly with a modified carbohydrate profile in the standard diet therapy of patients with type 2 diabetes during 2 weeks was accompanied by positive dynamics of carbohydrate and lipid metabolism, as well as a decrease in the content of lipid peroxidation products in blood plasma: reducing the level of conjugated dienes and malondialdehyde averaged 15.2 and 17.4% from baseline (p<0.05), respectively, while content of lipid peroxidation products in blood plasma did not changed in patients from the control group.
[Mh] Termos MeSH primário: Metabolismo dos Carboidratos/efeitos dos fármacos
Carboidratos da Dieta/administração & dosagem
Alimentos Especializados
Metabolismo dos Lipídeos/efeitos dos fármacos
Obesidade
[Mh] Termos MeSH secundário: Adulto
Idoso
Diabetes Mellitus Tipo 2/dietoterapia
Diabetes Mellitus Tipo 2/metabolismo
Diabetes Mellitus Tipo 2/patologia
Feminino
Seres Humanos
Masculino
Meia-Idade
Obesidade/dietoterapia
Obesidade/metabolismo
Obesidade/patologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Dietary Carbohydrates)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180216
[Lr] Data última revisão:
180216
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180130
[St] Status:MEDLINE


  3 / 163 MEDLINE  
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[PMID]:28946309
[Au] Autor:Milesevic J; Samaniego L; Kiely M; Glibetic M; Roe M; Finglas P
[Ad] Endereço:EuroFIR AISBL, Brussels, Belgium; Institute for Medical Research, University of Belgrade, Serbia; Faculty of Technology, University of Novi Sad, Serbia. Electronic address: jelena.milesevic@gmail.com.
[Ti] Título:Specialized food composition dataset for vitamin D content in foods based on European standards: Application to dietary intake assessment.
[So] Source:Food Chem;240:544-549, 2018 Feb 01.
[Is] ISSN:0308-8146
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:A review of national nutrition surveys from 2000 to date, demonstrated high prevalence of vitamin D intakes below the EFSA Adequate Intake (AI) (<15µg/d vitamin D) in adults across Europe. Dietary assessment and modelling are required to monitor efficacy and safety of ongoing strategic vitamin D fortification. To support these studies, a specialized vitamin D food composition dataset, based on EuroFIR standards, was compiled. The FoodEXplorer™ tool was used to retrieve well documented analytical data for vitamin D and arrange the data into two datasets - European (8 European countries, 981 data values) and US (1836 data values). Data were classified, using the LanguaL™, FoodEX2 and ODIN classification systems and ranked according to quality criteria. Significant differences in the content, quality of data values, missing data on vitamin D and 25(OH)D and documentation of analytical methods were observed. The dataset is available through the EuroFIR platform.
[Mh] Termos MeSH primário: Vitamina D/análise
[Mh] Termos MeSH secundário: Europa (Continente)
Alimentos Fortificados
Alimentos Especializados
Seres Humanos
Vitaminas
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Vitamins); 1406-16-2 (Vitamin D)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171128
[Lr] Data última revisão:
171128
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170927
[St] Status:MEDLINE


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[PMID]:28098769
[Au] Autor:Haro-Vicente JF; Bernal-Cava MJ; Lopez-Fernandez A; Ros-Berruezo G; Bodenstab S; Sanchez-Siles LM
[Ad] Endereço:Department of Research and Development, Hero Group, Alcantarilla, Murcia 30820, Spain. jfrancisco.haro@hero.es.
[Ti] Título:Sensory Acceptability of Infant Cereals with Whole Grain in Infants and Young Children.
[So] Source:Nutrients;9(1), 2017 Jan 13.
[Is] ISSN:2072-6643
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:In many countries, infant cereals are one of the first foods introduced during the complementary feeding stage. These cereals are usually made with refined cereal flours, even though several health benefits have been linked to the intake of whole grain cereals. Prior evidence suggests that food preferences are developed at early stages of life, and may persist in later childhood and adulthood. Our aim was to test whether an infant cereal with 30% of whole grain was similarly accepted both by parents and infants in comparison to a similar cereal made from refined flour. A total of 81 infants between 4 and 24 months old were included in the study. Parent-infant pairs participated in an 8-day experimental study. Acceptance was rated on hedonic scales (4-points for infants and 7-points for parents). Other attributes like color, smell, and taste were evaluated by the parents. Acceptability for infant cereals with whole grain and refined cereals was very similar both for infants (2.30 ± 0.12 and 2.32 ± 0.11, = 0.606) and parents (6.1 ± 0.8 and 6.0 ± 0.9, = 0.494). Therefore, our findings show that there is an opportunity to introduce whole grain cereals to infants, including those who are already used to consuming refined infant cereals, thereby accelerating the exposure of whole grain in early life.
[Mh] Termos MeSH primário: Comportamento do Consumidor
Alimentos Especializados
Paladar
Grãos Integrais/química
[Mh] Termos MeSH secundário: Adulto
Pré-Escolar
Feminino
Farinha
Preferências Alimentares
Seres Humanos
Lactente
Fórmulas Infantis/química
Fenômenos Fisiológicos da Nutrição do Lactente
Masculino
Leite Humano
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170613
[Lr] Data última revisão:
170613
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170119
[St] Status:MEDLINE


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[PMID]:28031190
[Au] Autor:Rytter MJ; Babirekere-Iriso E; Namusoke H; Christensen VB; Michaelsen KF; Ritz C; Mortensen CG; Mupere E; Friis H
[Ad] Endereço:Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark; marenrytter@hotmail.com.
[Ti] Título:Risk factors for death in children during inpatient treatment of severe acute malnutrition: a prospective cohort study.
[So] Source:Am J Clin Nutr;105(2):494-502, 2017 Feb.
[Is] ISSN:1938-3207
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Children who receive in-hospital treatment of severe acute malnutrition often have high mortality rates, and the reasons are not well understood. OBJECTIVE: We assessed risk factors for death in children who were treated for malnutrition in a hospital. DESIGN: In a prospective observational study of 120 children who were receiving in-hospital treatment of severe acute malnutrition in Uganda with therapeutic formulas F-75 and F-100, we collected data on symptoms, clinical findings, plasma markers of refeeding syndrome (electrolytes and phosphate), and acute phase reactants, and recorded the nutritional therapy given in hospital. RESULTS: Seventeen children (14%) died. Clinical risk factors for death were the presence of oral thrush (HR: 5.0; 95% CI: 1.6, 15.2), a caretaker-reported severity of illness on a visual analog scale (HR: 1.7; 95% CI: 1.1, 2.6), impaired consciousness (HR: 16.7; 95% CI: 3.1, 90.4), and a capillary refill time >2 s (HR: 3.9; 95% CI: 1.4, 11.3). HIV infection was not associated with mortality (HR: 3.0; 95% CI: 0.7, 12.4), which was most likely due to low power. Biochemical risk factors were a plasma C-reactive protein concentration >15 mg/L on admission and low plasma phosphate that was measured on day 2 (HR: 8.7; 95% CI: 2.5, 30.1), particularly in edematous children. The replacement of F-75 with unfortified rice porridge to ameliorate diarrhea was associated with a higher risk of death, particularly if given during the first 2 d (HR: 5.0; 95% CI: 1.9, 13.3), which was an association that remained after adjustment for potential confounders (HR: 69.5; 95% CI: 7.0, 694.6). CONCLUSIONS: Refeeding syndrome may occur in children who are treated for malnutrition, even with moderately low plasma phosphate, and, in particular, in children with edematous malnutrition. The replacement of F-75 with unfortified rice porridge is associated with increased risk of death, which is possibly mediated by lowering plasma phosphate. The identified clinical risk factors may potentially improve the triage of children with malnutrition. This trial was registered at www.isrctn.com as ISRCTN55092738.
[Mh] Termos MeSH primário: Pacientes Internados
Desnutrição Aguda Grave/mortalidade
Desnutrição Aguda Grave/terapia
[Mh] Termos MeSH secundário: Proteína C-Reativa/metabolismo
Pré-Escolar
Diarreia/terapia
Feminino
Seguimentos
Alimentos Especializados
Infecções por HIV/mortalidade
Infecções por HIV/terapia
Seres Humanos
Lactente
Masculino
Fosfatos/administração & dosagem
Fosfatos/sangue
Estudos Prospectivos
Síndrome da Realimentação/mortalidade
Síndrome da Realimentação/terapia
Fatores de Risco
Uganda
[Pt] Tipo de publicação:JOURNAL ARTICLE; OBSERVATIONAL STUDY
[Nm] Nome de substância:
0 (Phosphates); 9007-41-4 (C-Reactive Protein)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170627
[Lr] Data última revisão:
170627
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:161230
[St] Status:MEDLINE
[do] DOI:10.3945/ajcn.116.140822


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[PMID]:27727008
[Au] Autor:Zingone F; Bucci C; Iovino P; Ciacci C
[Ad] Endereço:Celiac Center, Gastrointestinal Unit, AOU S. Giovanni di Dio e Ruggi d'Aragona, University of Salerno, Salerno, Italy. Electronic address: fabiana.zingone@outlook.com.
[Ti] Título:Consumption of milk and dairy products: Facts and figures.
[So] Source:Nutrition;33:322-325, 2017 Jan.
[Is] ISSN:1873-1244
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: Consumption of milk has been declining sharply in recent decades, particularly in developed countries. One of the reasons for this decline is the diagnosis or perception of lactose intolerance. The aim of this study was to investigate average consumption of milk and dairy products in the Campania region of Italy, one of the main producers of dairy products in the country. METHODS: Individuals aged 18 to 75 y and living in Campania were invited to answer an online questionnaire regarding their average consumption of milk and dairy products. The questionnaire was posted on the public access hospital site, as well as on several Facebook pages of friends and hospital personnel. RESULTS: The study found that 22.2% (260 of 1173) of responders from Campania do not drink milk, and 18.1% (213 of 1173) drink lactose-free milk, mainly because of gastrointestinal symptoms. The vast majority of the sample population chose to avoid consuming milk without undergoing the breath test for lactose intolerance or consulting a doctor. Women and underweight people drink more lactose-free milk than milk containing lactose. The population sample does not avoid dairy products; rather, they seem to be consumed quite frequently. CONCLUSION: The data support the need for mandatory implementation of a nutritional campaign to increase understanding regarding, for example, unnecessary avoidance of milk and excessive consumption of cheese.
[Mh] Termos MeSH primário: Laticínios
Dieta
Leite
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Animais
Estudos de Coortes
Laticínios/efeitos adversos
Dieta/etnologia
Inquéritos sobre Dietas
Feminino
Alimentos Especializados
Seres Humanos
Internet
Itália
Intolerância à Lactose/dietoterapia
Intolerância à Lactose/fisiopatologia
Masculino
Meia-Idade
Leite/efeitos adversos
Autorrelato
Caracteres Sexuais
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161012
[St] Status:MEDLINE


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[PMID]:26252442
[Au] Autor:Corstens MN; Berton-Carabin CC; de Vries R; Troost FJ; Masclee AA; Schroën K
[Ad] Endereço:a Department of Agrotechnology & Food Sciences , Food Process Engineering Group, Wageningen University and Research Center , Wageningen , The Netherlands.
[Ti] Título:Food-grade micro-encapsulation systems that may induce satiety via delayed lipolysis: A review.
[So] Source:Crit Rev Food Sci Nutr;57(10):2218-2244, 2017 Jul 03.
[Is] ISSN:1549-7852
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The increasing prevalence of overweight and obesity requires new, effective prevention and treatment strategies. One approach to reduce energy intake is by developing novel foods with increased satiating properties, which may be accomplished by slowing down lipolysis to deliver substrates to the ileum, thereby enhancing natural gut-brain signaling pathways of satiety that are normally induced by meal intake. To develop slow release food additives, their processing in the gastrointestinal tract has to be understood; therefore, we start from a general description of the digestive system and relate that to in vitro modeling, satiety, and lipolytic mechanisms. The effects of physicochemical lipid composition, encapsulation matrix, and interfacial structure on lipolysis are emphasized. We give an overview of techniques and materials used, and discuss partitioning, which may be a key factor for encapsulation performance. Targeted release capsules that delay lipolysis form a real challenge because of the high efficiency of the digestive system; hardly any proof was found that intact orally ingested lipids can be released in the ileum and thereby induce satiety. We expect that this challenge could be tackled with structured o/w-emulsion-based systems that have some protection against lipase, e.g., by hindering bile salt adsorption and/or delaying lipase diffusion.
[Mh] Termos MeSH primário: Gorduras na Dieta/administração & dosagem
Digestão
Regulação para Baixo
Alimentos Especializados
Lipólise
Modelos Biológicos
Sobrepeso/dietoterapia
[Mh] Termos MeSH secundário: Animais
Depressores do Apetite/administração & dosagem
Depressores do Apetite/metabolismo
Depressores do Apetite/uso terapêutico
Gorduras na Dieta/metabolismo
Gorduras na Dieta/uso terapêutico
Emulsões
Ingestão de Energia
Aditivos Alimentares/metabolismo
Aditivos Alimentares/uso terapêutico
Tecnologia de Alimentos/tendências
Seres Humanos
Absorção Intestinal
Sobrepeso/metabolismo
Resposta de Saciedade
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Appetite Depressants); 0 (Dietary Fats); 0 (Emulsions); 0 (Food Additives)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170815
[Lr] Data última revisão:
170815
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150808
[St] Status:MEDLINE
[do] DOI:10.1080/10408398.2015.1057634


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[PMID]:27989253
[Au] Autor:Keane KM; Haskell-Ramsay CF; Veasey RC; Howatson G
[Ad] Endereço:1Department of Sport, Exercise and Rehabilitation, Faculty of Health and Life Sciences,Northumbria University,Newcastle Upon Tyne NE1 8ST,UK.
[Ti] Título:Montmorency Tart cherries (Prunus cerasus L.) modulate vascular function acutely, in the absence of improvement in cognitive performance.
[So] Source:Br J Nutr;116(11):1935-1944, 2016 Dec.
[Is] ISSN:1475-2662
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Cerebral blood volume and metabolism of oxygen decline as part of human ageing, and this has been previously shown to be related to cognitive decline. There is some evidence to suggest that polyphenol-rich foods can play an important role in delaying the onset or halting the progression of age-related health disorders such as CVD and Alzheimer's disease and to improve cognitive function. In the present study, an acute, placebo-controlled, double-blinded, cross-over, randomised Latin-square design study with a washout period of at least 14 d was conducted on twenty-seven, middle-aged (defined as 45-60 years) volunteers. Participants received either a 60 ml dose of Montmorency tart cherry concentrate (MC), which contained 68·0 (sd 0·26) mg cyanidin-3-glucoside/l, 160·75 (sd 0·55) mean gallic acid equivalent/l and 0·59 (sd 0·02) mean Trolox equivalent/l, respectively, or a placebo. Cerebrovascular responses, cognitive performance and blood pressure were assessed at baseline and 1, 2, 3 and 5 h following consumption. There were significant differences in concentrations of total Hb and oxygenated Hb during the task period 1 h after MC consumption (P≤0·05). Furthermore, MC consumption significantly lowered systolic blood pressure (P≤0·05) over a period of 3 h, with peak reductions of 6±2 mmHg at 1 h after MC consumption relative to the placebo. Cognitive function and mood were not affected. These results show that a single dose of MC concentrate can modulate certain variables of vascular function; however, this does not translate to improvements in cognition or mood.
[Mh] Termos MeSH primário: Vasos Sanguíneos/fisiologia
Circulação Cerebrovascular
Alimentos Especializados
Sucos de Frutas e Vegetais
Pré-Hipertensão/prevenção & controle
Prunus avium
Doenças Vasculares/prevenção & controle
[Mh] Termos MeSH secundário: Vasos Sanguíneos/fisiopatologia
Disfunção Cognitiva/sangue
Disfunção Cognitiva/diagnóstico por imagem
Disfunção Cognitiva/fisiopatologia
Disfunção Cognitiva/prevenção & controle
Estudos Cross-Over
Método Duplo-Cego
Inglaterra
Feminino
Hemoglobinas/análise
Hemoglobinas/química
Seres Humanos
Masculino
Fadiga Mental/sangue
Fadiga Mental/diagnóstico por imagem
Fadiga Mental/fisiopatologia
Fadiga Mental/prevenção & controle
Meia-Idade
Transtornos do Humor/sangue
Transtornos do Humor/diagnóstico por imagem
Transtornos do Humor/fisiopatologia
Transtornos do Humor/prevenção & controle
Oxirredução
Córtex Pré-Frontal/irrigação sanguínea
Córtex Pré-Frontal/diagnóstico por imagem
Pré-Hipertensão/sangue
Pré-Hipertensão/fisiopatologia
Análise e Desempenho de Tarefas
Ultrassonografia Doppler Transcraniana
Doenças Vasculares/sangue
Doenças Vasculares/diagnóstico por imagem
Doenças Vasculares/fisiopatologia
[Pt] Tipo de publicação:CLINICAL TRIAL; JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Hemoglobins)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170515
[Lr] Data última revisão:
170515
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161220
[St] Status:MEDLINE
[do] DOI:10.1017/S0007114516004177


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[PMID]:27809945
[Au] Autor:Chungchunlam SM; Henare SJ; Ganesh S; Moughan PJ
[Ad] Endereço:1Riddet Institute,Massey University,Private Bag 11-222,Palmerston North 4442,New Zealand.
[Ti] Título:Effect of whey protein and a free amino acid mixture simulating whey protein on measures of satiety in normal-weight women.
[So] Source:Br J Nutr;116(9):1666-1673, 2016 Nov.
[Is] ISSN:1475-2662
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Dietary protein is considered more satiating than carbohydrate, and whey protein is more satiating than other protein sources. The purported satiating effect of whey protein may be due to direct effects of the unique mixture of proteins in whey, due to the effects of peptides released upon digestion and/or its amino acid composition. The objective of the present study was to compare the satiating effects of intact whey protein isolate (WPI) or a free amino acid mixture (AAM) simulating the amino acid composition of the WPI. A single-blind completely randomised block design included twenty, healthy, adult women (age 24·2 (sem 0·8) years) of normal weight (BMI 22·7 (sem 0·4) kg/m2). Following consumption of isoenergetic (approximately 1800 kJ) preload meals enriched (52 g amino acid equivalent) with WPI or AAM, consumption of an ad libitum test meal 120 min later and subjective feelings of appetite using visual analogue scales (VAS) were determined. There were no significant differences (P=0·24) in the ad libitum test meal intakes between the WPI (268·5 (sem 27·3) g) and the AAM (238·4 (sem 22·7) g) preload meals. Subjective VAS ratings of appetite did not differ significantly between the WPI and the AAM preload meals (P>0·05). Intact whey protein and a free AAM simulating the whey protein showed similar effects on satiety. This suggests that the satiating effect of whey protein may be related to its specific amino acid composition.
[Mh] Termos MeSH primário: Aminoácidos/administração & dosagem
Depressores do Apetite/administração & dosagem
Desjejum
Condimentos
Alimentos Especializados
Resposta de Saciedade
Proteínas do Soro do Leite/administração & dosagem
[Mh] Termos MeSH secundário: Adulto
Aminoácidos/efeitos adversos
Animais
Depressores do Apetite/efeitos adversos
Condimentos/efeitos adversos
Ingestão de Energia
Feminino
Preferências Alimentares
Alimentos Formulados/efeitos adversos
Alimentos Especializados/efeitos adversos
Seres Humanos
Almoço
Nova Zelândia
Período Pós-Prandial
Autorrelato
Método Simples-Cego
Proteínas do Soro do Leite/efeitos adversos
Adulto Jovem
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Amino Acids); 0 (Appetite Depressants); 0 (Whey Proteins)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170522
[Lr] Data última revisão:
170522
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161105
[St] Status:MEDLINE


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Fotocópia
[PMID]:27737722
[Au] Autor:Ulven SM; Leder L; Elind E; Ottestad I; Christensen JJ; Telle-Hansen VH; Skjetne AJ; Raael E; Sheikh NA; Holck M; Torvik K; Lamglait A; Thyholt K; Byfuglien MG; Granlund L; Andersen LF; Holven KB
[Ad] Endereço:1Department of Health, Nutrition and Management, Faculty of Health Sciences,Oslo and Akershus University College of Applied Sciences,PO Box 4,St. Olavsplass,0130 Oslo,Norway.
[Ti] Título:Exchanging a few commercial, regularly consumed food items with improved fat quality reduces total cholesterol and LDL-cholesterol: a double-blind, randomised controlled trial.
[So] Source:Br J Nutr;116(8):1383-1393, 2016 Oct.
[Is] ISSN:1475-2662
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The healthy Nordic diet has been previously shown to have health beneficial effects among subjects at risk of CVD. However, the extent of food changes needed to achieve these effects is less explored. The aim of the present study was to investigate the effects of exchanging a few commercially available, regularly consumed key food items (e.g. spread on bread, fat for cooking, cheese, bread and cereals) with improved fat quality on total cholesterol, LDL-cholesterol and inflammatory markers in a double-blind randomised, controlled trial. In total, 115 moderately hypercholesterolaemic, non-statin-treated adults (25-70 years) were randomly assigned to an experimental diet group (Ex-diet group) or control diet group (C-diet group) for 8 weeks with commercially available food items with different fatty acid composition (replacing SFA with mostly n-6 PUFA). In the Ex-diet group, serum total cholesterol (P<0·001) and LDL-cholesterol (P<0·001) were reduced after 8 weeks, compared with the C-diet group. The difference in change between the two groups at the end of the study was -9 and -11 % in total cholesterol and LDL-cholesterol, respectively. No difference in change in plasma levels of inflammatory markers (high-sensitive C-reactive protein, IL-6, soluble TNF receptor 1 and interferon-γ) was observed between the groups. In conclusion, exchanging a few regularly consumed food items with improved fat quality reduces total cholesterol, with no negative effect on levels of inflammatory markers. This shows that an exchange of a few commercially available food items was easy and manageable and led to clinically relevant cholesterol reduction, potentially affecting future CVD risk.
[Mh] Termos MeSH primário: Doenças Cardiovasculares/prevenção & controle
LDL-Colesterol/sangue
Colesterol/sangue
Ácidos Graxos Ômega-6/uso terapêutico
Alimentos Especializados
Dieta Saudável
Hipercolesterolemia/dietoterapia
[Mh] Termos MeSH secundário: Adulto
Idoso
Doenças Cardiovasculares/epidemiologia
Doenças Cardiovasculares/etnologia
Doenças Cardiovasculares/etiologia
Dieta Hiperlipídica/efeitos adversos
Dieta Hiperlipídica/economia
Dieta Hiperlipídica/etnologia
Método Duplo-Cego
Ácidos Graxos Ômega-6/administração & dosagem
Ácidos Graxos Ômega-6/economia
Feminino
Seguimentos
Qualidade dos Alimentos
Alimentos Especializados/economia
Dieta Saudável/economia
Dieta Saudável/etnologia
Seres Humanos
Hipercolesterolemia/sangue
Hipercolesterolemia/etnologia
Hipercolesterolemia/fisiopatologia
Perda de Seguimento
Masculino
Meia-Idade
Noruega/epidemiologia
Pacientes Desistentes do Tratamento
Fatores de Risco
Índice de Gravidade de Doença
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Cholesterol, LDL); 0 (Fatty Acids, Omega-6); 97C5T2UQ7J (Cholesterol)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170519
[Lr] Data última revisão:
170519
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161015
[St] Status:MEDLINE



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